Spinal Cord for FBS

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    The spinal cord begin as a

    continuation

    of the medulla oblongata.

    In adults, 42-45cm in long

    Extend from the foramen magnum

    in theoccipital bone to the level of the

    L1 or L2(in adult)

    In newborn infants, it extends to

    the third or fourth lumbar vertebra

    Elongation of the spinal cord stops

    around age 4 or 5, but growthof the vertebral column continues

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    Enlarged in two regions :

    1. Cervical enlargment

    (C4-T1 segment ofthe spinal cord)

    2. Lumbosacral enlargment

    (T11-S1 segment of

    the spinal cord)

    The spinal cord occupies

    only the superiortwo thirds of the

    vertebral canal

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    The conus medullaris is tapering inferior end,

    terminate as high as T12 vertebrae or

    as low as L3 vertebrae

    Cauda equina is bundle ofspinal nerve roots

    arising from the lumbosacral enlargment & the

    medullary cone, caudal to the termination

    of the spinal cord resembles a horses tail

    filum terminale:

    -arising from the tip of the conus medullaris,

    descend among the spinal roots in the cauda equina

    -an anchor for the inferior end of spinal cord

    and the spinal meninges

    Two parts of filum terminale :1. Pial part / internal terminal filum

    2. Dural part/external terminal filum

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    Vertebral

    column

    Vertebralligament

    Meninges

    CSF

    Denticulateligament

    Cushion of fat &

    connective tissuelocated in epidural space

    Denticulate ligament :

    Triangular-shaped membranous extensions of

    the pia mater

    suspend the spinal cord in the middle of its duralsheath

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    Consist of dura mater, arachnoidmater & pia mater

    Spinal dura mater :

    Composed mainly of tough

    fibrous with some elastic tissue, is

    the outermost covering

    membrane of the spinal cord

    The spinal dura forms the spinal

    dural sac, a long tubular sheath

    within the vertebral canal.

    The sac is anchored inferiorly to

    the coccyx by the filum terminale

    The spinal dura mater isseparated from the periosteum-

    covered bone and the ligaments

    that form the walls of the vertebral

    canal by the epidural space.

    Content of epidural space :

    Fat, internal vertebral venous

    plexuses, root of spinal nerves

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    Spinal arachnoid mater :

    is a delicate, avascular membrane composed of fibrous and elastic tissue

    Their apposition is the dura-arachnoid interface , often erroneously referred toas the subdural space.

    The spinal arachnoid is separated from the pia mater on the surface of the

    spinal cord by the subarachnoid space.

    Content of subarachnoid space :CSF; radicular, segmental, medullary, andspinal arteries; veins; arachnoid trabeculae.

    The enlargement of the subarachnoid space in the dural sac, caudal to the

    conus medullaris and containing CSF and the cauda equina, is the lumbar

    cistern. It extends from the L2 vertebra to the second segment of the sacrum.

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    L2-S2

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    Spinal pia mater :

    the innermost covering membrane of the spinal cord, is thin and transparent,

    and closely follows all the surface features of the spinal cord

    The spinal pia also directly covers the roots of the spinal nerves and the

    spinal blood vessels. Inferior to the conus medullaris, the spinal pia continues

    as the filum terminale

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    The spinal cord is suspended in the dural sac by the

    filum terminale and the right and left denticulate

    ligaments

    Denticulate ligament (sawtooth) :

    Triangular-shaped membranous extensions of the pia

    mater

    suspend the spinal cord in the middle of its dural sheath

    The 20-22 sawtooth-like processes attach to the inner

    surface of the arachnoid-lined dural sac.

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    The arteries derive from :

    1.Vertebral artery

    2. Ascending cervical artery

    3. Deep cervical artery

    4. Intercostal artery5. Lumbar artery

    6. Lateral sacral artery

    7. Three longitudinal artery :

    An anterior spinal artery

    Two posterior spinal artery

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    The arteries derive from :

    8. Anterior segmental artery

    9. Posterior segmental artery

    10. The great anterior segmental

    medullary artery (ofAdamkiewicz)

    Contribute to the longitudinal

    artery

    The great anterior segmental

    medullary artery (ofAdamkiewicz) is the largest

    segmental medullary artery

    supply cervical & lumbosacral

    enlargment

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    The arteries derive from :

    11. Radicular artery

    At levels where there are no

    segmental medullary artery,radicular artery supplies the

    posterior & anterior roots of

    the spinal nerves

    Radicular artery are shown

    at only the cervical &thoracic level, but they also

    occur at the lumbar & sacral

    levels

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    The arteries derive from :

    12. Sulcal artery

    Arise from the anterior spinal

    artery & enter the spinal cordthrough anterior median

    fissure

    Supplies approximately two

    thirds of the cross sectional

    area of the spinal cord

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    1. three anterior spinal veins

    2. three posterior spinal veins

    Drain up to :

    1. 12 anterior medullary veins

    2. 12 posterior medullary veins

    3. radicular veins

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    The gray matter on each side of the spinal cord is subdivided into regions called

    horns.

    The gray matter consist of :

    The posterior (dorsal) gray horns

    The anterior (ventral) gray horns

    The lateral gray horns

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    contain cell bodies and axons of interneurons as well as axonsof incoming sensory neurons.

    The posterior(dorsal) gray

    horns

    contain somatic motor nuclei, which are clusters of cell bodiesof somatic motor neurons that provide nerve impulses forcontraction of skeletal muscles

    The anterior(ventral) gray

    horns

    present only in thoracic and upper lumbar segments of thespinal cord.

    contain autonomic motor nuclei, which are clusters of cellbodies of autonomic motor neurons that regulate the activityof cardiac muscle, smooth muscle, and glands.

    The lateralgray horns

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    The white matter on each side of the spinal cord is subdivided into regions called

    columns/ funiculus

    The white matter consist of :

    The posterior (dorsal) white columns /funiculus

    The anterior (ventral) white columns/funiculus The lateral white columns/funiculus

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    Each column in turn contains distinct bundles of axons

    having a common origin or destination and carrying similar

    information.

    These bundles, which may extend long distances up or

    down the spinal cord, are called tracts.

    Recall that tracts are bundles of axons in the CNS,whereas nerves are bundles of axons in the PNS

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    In transverse sections of the spinal cord, the anterior and posterior gray

    columns on each side are connected by a transverse gray commissure; the

    gray matter resembles the letter H

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    In the center of the gray commissure is situated the central canal.