Smart solutions for faster product and process innovation InsightFaraday A New Approach to Boosting R&D Productivity

Smart solutions for faster product and process innovation

InsightFaraday

A New Approach to Boosting R&D

Productivity


Our Purpose

To promote the development and exploitation of

high throughput technologies (HTT) to enable

increased R&D productivity

Leaner laboratory processes

Efficient use of valuable R&D resource

Faster Innovation


Office in Runcorn, Cheshire

Core partner is LGC

Customers include:

The Operation

Universities

HTT user companiesChemical, Agrochem, Pharmaceutical, Home & Personal Care, Biotech, R&D service providers...

HTT suppliers


Lean Lab ?


High Throughput Lab

How ?

How Much ?

£ £ £ $ $ $ € € €


High Throughput Technologies

Tools for boosting R&D productivity

Software DoE in-silico simulation LIMS Control Mass data handling Data mining Multivariate statistics Data visualisation

Hardware Robots Electronics Parallel (micro)reactors Precision dosing Measurement devices Storage systems Tags & readers Bespoke automation

Interdisciplinary

Disruptive


LabSmart Laboratory Audit Service Facilitating the use of HTT Capitalising on Investment Maximising Cost Benefit

…boosting R&D productivity


Insight’s Laboratory Audit

Produce figures for improved R&D productivity

Convince senior management to invest in HTT


Step 1Map the laboratory work flow identify unit operations and resources

Step 2Run the LabSmart™ model - validate for current data

calculate sample throughput monitor resource utilisation identify bottle neck operations

Step 3Identify options for increasing throughput

Step 4Model “high-throughput” scenarios Find optimum solution (cost & throughput)

The Audit Process


A Laboratory Case Study

(LGC POET team)


Situation September 2003

Good Sample numbers increasing rapidly

Bad Turnaround times were increasing Costs were increasing Internal delivery conflicts Erosion of quality Customer dissatisfaction

Danger of losing the contract


Approach

New Management structure

First team to undergo LabSmart Audit

Concentrated on:>work flows>data transfers>sample preparation>analytical methods (repeat rates, time,

cost)> logistics>customer needs


Improvement Plan

Aims:Reduce turnaround timesEliminate backlogReturn to profit

S O N D J F M A M J J ALaboratory AuditRelocationMethod DevelopmentLIMSInstallation & validation of equipment

Activity2003 2004


Original LaboratoryJob Duration (hrs)

0:00:00

48:00:00

96:00:00

144:00:00

192:00:00

240:00:00

288:00:00

336:00:00

384:00:00

432:00:00

480:00:00

1 5 9 13 17 21 25 29 33 37 41 45 49 53 57 61 65 69 73 77 81 85 89 93 97 101

105

109

113

117

121

125

129

133

137

141

145

149


Optimised LaboratoryJob Duration (hrs)

0:00:00

48:00:00

96:00:00

144:00:00

192:00:00

240:00:00

288:00:00

336:00:00

384:00:00

1 5 9 13 17 21 25 29 33 37 41 45 49 53 57 61 65 69 73 77 81 85 89 93 97 101

105

109

113

117

121

125

129

133

137

141

145

149


Operational Improvements

Laboratory space -60m2 (1.5 modules)

Turnaround times 5-10 from >60 days

Capacity Doubled (>200 p/m)

Backlog From over 250 to Nil

40% reduction in staff costs (13.5 to 8.5 FTE)

Leaner, cheaper processes


Analytical Improvements

Data transfers reduced by 70%

All instruments running on same data acquisition system

Sample preparation time cut

Faster analytical methods

Sample volume required cut by 80%

LIMS automated invoicing

Higher reproducibility & improved quality


Result

Payback in 4 Months

Increased Customer Satisfaction

Increased Employee Satisfaction


Application Areas

Sector- specialty chemicals- home & personal care- life sciences- materials- ….

Applications- formulation- synthesis- measurement- process development- ….

Technology- new platforms- physical measurement- data handling- modelling- …. What can HTT do for you?

Documents

Smart solutions for faster product and process innovation InsightFaraday A New Approach to Boosting R&D Productivity