SKYLUXTM Low-Protein-Binding-PP...Hong Kong : +852 - 23190918 Shanghai : +86-13710121239 Guangzhou : + 86-20-83362402 E-mail : [email protected] Website: SKYLUXTM …

SKYLUXTM Low-Protein-Binding-PP

Less Lost Protein

For More Reliable Proteomics

Dec., 2019

Proteomics & Protein research

Proteomic is a growing field of interest.

To study protein function is often possible to know the effect of a particular protein on development or a physiological function by introducing it into an organism.

The rising impact of proteomics on clinical and industrial research, academic and research institutions are integrating proteomics as an important parts of their course curriculum.

SKYLUXTM Low Protein Binding PPLess Lost Protein For More Reliable Proteomics

SKYLUX is trademark of DragonChem Limited

Protein Research

A major issue faced is the loss of protein to polypropylene tubes,

as well to other plastic containers.

Chart : https://www.semanticscholar.org



Study Result : Protein adsorption properties are varies on different plastic resins

Pro

tein

Lo

ss R

ate

%

Chart : https://jpharmsci.org



0

10

20

30

40

50

60

70

80

90

100

0hr 24hr 48hr 72hr 96hr

PP-1

PP-2

PP-3

PP-4

PP-5

Pro

tein

Re

cove

ry R

ate

Time of protein storage (Hour)

Protein recovery rate test of untreated PP storage tube

Source : AVI

Study Result : Protein recovery rate is low at 20%

on an untreated PP storage tube after 96 hours


Innovative product

SKYLUX Low-Protein-Binding Polypropylene(PP) Resin is developed by DragonChem Limited

With SKYLUX Low-Protein-Binding-PP Resin, protein recovery rate

of consumables for proteomics and protein research could be maximized and consequently protein loss could be minimized

Benefits with SKYLUX Low-Protein-Binding-PP

✓No post-treatments are deeded on end-products

✓No additives are needed on consumable manufacturing

✓Conventional injection machines can be used

✓Conventional mold can be used

✓Food contact safe

✓Low extractables



Innovative Technology (Patent Pending)

SKYLUX PP low protein binding

PP is a re-engineered polymer in formulation



Innovative technology : Test Result

Protein Stain Quick Test for 10minutes(The darker color the more protein residual are )

Tube made of SKYLUX LP810 Low Protein Binding Tube in the market



BSA Adsorption Study on chip samples




BSA Adsorption Study on chip samples(concentration : 0.124g/ml) Test by : AVI




0.00%

0.50%

1.00%

1.50%

2.00%

2.50%

3.00%

3.50%

24hr 48hr 72hr

Random PP 1.5ml tube SKYLUX LP810 1.5ml tube

BSA Adsorption Study (Average result of 10 tubes)

BS

A R

esi

du

al R

ate

(BSA Concentration : 1mg/ml)

Tested by AVI




94.50%

95.00%

95.50%

96.00%

96.50%

97.00%

97.50%

98.00%

98.50%

99.00%

99.50%

24hr 72hr

Import 1.5ml tube

SKYLUX 1.5ml tube

Nanodrop BSA Recovery Study on 1.5ml tubes

Test by : Bang Fei

Re

cove

ry R

ate




56.00%

58.00%

60.00%

62.00%

64.00%

66.00%

68.00%

70.00%

24hr 7days

Import 1.5ml tube

SKYLUX 1.5ml tube

Bradford BSA Recovery Study on 1.5ml tubes

Re

cove

ry R

ate

Test by : Bang Fei




Characteristics of SKYLUX Low Protein Binding PP LP810

◆Good Heat Resistant ◆ High Transparency

◆ Good Rigidity ◆ Low Extractables

Property Unit Test Method Test Condition LP810

Melt Flow Index dg/min ASTM D1238 230℃×2.16Kg 10

Specific Gravity g/cm3 ASTM D792 0.9

Tensile Elongation at Break % ASTM D638 23℃ 10

Tensile Strength at Yield kg/cm2 ASTM D638 350

Flexural Modulus kg/cm2 ASTM D790 23℃ 14000

Notched Izod Impact Strength kg-cm/cm ASTM D256 23℃/3.2mm 5

Heat Deflection Temperature ℃ ASTM D648 95

Vicat Softening Temperature ℃ ASTM D1525 130


Application of SKYLUX Low Protein Binding PP

1.5ml & 2.0ml Low Protein Binding Micro Centrifuge Tubes

made with SKYLUX LP810

Source : www.bangfeibio.com

Characteristics :

✓ High protein sample recovery rate

✓ Free of surface coating✓ Free of DNA、DNase、Rnase✓ Free of PCR inhibitors✓ Centrifuge speed up to

30,000RCF✓ Autoclavable & Disposable



Potential application of SKYLUX Low Protein Binding PP

Preparation and/or Storage for

Proteins, Peptides, Antibodies …

Photo : http://proteomicsnews.blogspot.com , www.pasteur-kh.org




Housing of Low Protein Binding Cartridge/Syringe Filters

for better performance

Photo : www.jetbiofil.com

Photo : http://www.hqoptimalfilters.com




Consumables for protein purification and isolation researches




Immune Cell & Stem Cell storage :

To ensure the function and activity of the cells are not significantly affected



New SKYLUX Low Protein Binding PP are under developing …

Gamma Resistant

Homo/Random PP

Blow Molding Super High Impact, Izod Impact = HDPE

High Transparent Random PP

Super High Flow

(MI:50-70) Homo PP



Application development of SKYLUX Low Protein Binding PP

for your need !

Collaboration Win-Win



Inquiry & Technical Support :

Hong Kong : +852 - 23190918

Shanghai : +86-13710121239

Guangzhou : + 86-20-83362402

E-mail : [email protected]

Website : www.dragonchem.com



mailto:[email protected]

http://www.dragonchem.com/

Documents

SKYLUXTM Low-Protein-Binding-PP...Hong Kong : +852 - 23190918 Shanghai : +86-13710121239 Guangzhou : + 86-20-83362402 E-mail : [email protected] Website: SKYLUXTM …