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SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS B.Sc. (DEGREE) COURSE IN MICROBIOLOGY UNDER UGC-CBCS SYSTEM 2019

SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

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Page 1: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

SISTER NIVEDITA UNIVERSITY

SYLLABUS

FOR

THREE YEARS B.Sc. (DEGREE) COURSE

IN

MICROBIOLOGY

UNDER

UGC-CBCS SYSTEM

2019

Page 2: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Credit Distribution

Name of Department: Microbiology

Name of the UG program: B.Sc. (Hons.)

Duration of program: 6 Semester (3 years)

Head/ In-Charge of the department: Rajat Pal

Semester Credit

CC DSE GE AECC SEC USC Total/ Sem

1st 12 6 4 2 1 2 27

2nd 12 6 4 2 1 2 27

3rd 12 6 4 1 23

4th 12 6 4 1 23

5th 18 18

6th 18 18

Total Credit / Course 84 24 16 4 4 4

Total Credit 136

CC: Core Courses; GE: General Elective; AECC: Ability Enhancement Compulsory Course; SEC: Skill

Enhancement Courses; DSE: Discipline Specific Elective; USC: University specified course

Page 3: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

B.Sc. Microbiology (H) Course Structure

Category Course name Code Credit Teaching Scheme

L T P

Semester – I

CC – 1 Fundamentals of Biology 115211 6 4 0 4

CC – 2 Molecular Biology 115212 6 4 0 4

DSE – 1 Fundamentals of Chemistry 116211 6 4 0 4

GE – 1 Generic Elective * 4 3 1 0

AECC – 1 Communicative English 121115 2 2 0 0

SEC – 1 Mentored Seminar – I 115311 1 1 0 0

USC – I Foreign Language I (German/ Spanish/ Japanese) 127111/

127112/

127113

2 2 0 0

Total Credit = 27 Teaching Hour = 33

Semester – II

CC – 3 Bacteriology and Virology 115221 6 4 0 4

CC – 4 Bioenergetics and Metabolism 115222 6 4 0 4

DSE – 2 Biosafety and Bioethics 114123 2 2 0 0

DSE – 3 Bioinstrumentation Techniques 115123 4 3 1 0

GE – 2 Generic Elective * 4 3 1 0

AECC – 2 Environmental Science 115124 2 2 0 0

SEC – 2 Mentored Seminar – II 115321 1 1 0 0

USC – 2 Foreign Language II (German/ Spanish/ Japanese) 127121/

127122/

127123

2 2 0 0

Total Credit = 27 Teaching Hour = 31

Semester – III

CC – 5 Microbial genetics 115231 6 4 0 4

CC – 6 Recombinant DNA technology 115232 6 4 0 4

DSE – 4 Essential Physics 117233 6 4 0 4

GE – 3 Generic Elective * 4 3 1 0

SEC – 3 Mentored Seminar – III 115331 1 1 0 0

Total Credit = 23 Teaching Hour = 29

Semester – IV

CC – 7 Principles of Immunology 115241 6 4 0 4

CC – 8 Medical Microbiology and Drug delivery 115242 6 4 0 4

DSE – 5 Biostatistics and Bioinformatics 115243 6 4 0 4

GE – 4 Generic Elective * 4 3 1 0

SEC – 4 Mentored Seminar – IV 115341 1 1 0 0

Total Credit = 23 Teaching Hour = 29

Semester –V

CC – 9 Eukaryotic Microbiology 115251 6 4 0 4

CC – 10 Industrial and Food Microbiology 115252 6 4 0 4

CC - 11 Bacterial diversity 115253 6 4 0 4

Total Credit = 18 Teaching Hour = 24

Semester – VI

CC – 12 Sum-up Course 115261 6 4 0 4

CC – 13 Project 115363 12 0 0 24

Total Credit = 18 Teaching Hour = 32

Page 4: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

CORE COURSES (CC)

Page 5: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

First Semester

Course: CC1 – Fundamentals of Biology

Credit: 6 (4L-0T-2P)

Component: Theory

Module 1:

Unit 1: Organization in Nature: [8 L]

The Scientific Method; Linnaean hierarchical classification system; Evolution as a Unifying

Theme of Life; Origins of Life: Early Chemical and Biological Evolution; Oparin-Haldane model;

Miller-Urey experiment; Structure of Water; Properties of water.

Unit 2: Physical Foundations: [8 L]

Living Organisms Exist in a dynamic steady state; Macromolecules are major constituents of Cell;

Three-Dimensional Structure determined by Configuration and Conformation; Stereospecific

interactions between biomolecules; The flow of electrons provides energy for organisms; Energy

coupling links reactions in Biology-Enzymes promote sequences of chemical reactions;

Metabolism regulate and achieve balance and economy.

Unit 3: Evolutionary Foundations: [8 L]

Changes in the Hereditary instructions allow evolution; Chemical evolution can be simulated in

the laboratory; Abiogenesis; The First Cell Was Probably a Chemoheterotroph; Eukaryotic cells

evolved from prokaryotes in several stages; Molecular Anatomy Reveals Evolutionary

Relationships; population genetics.

Module 2:

Unit 1: Cellular structure and function: [10 L]

Prokaryotic and eukaryotic cell structure. Difference between prokaryotic and eukaryotic cell,

Plant and animal cell, Cell envelop, Cell organelles and their functions.

Unit 2: Transport across the membrane: [8 L]

Passive diffusion, facilitated diffusion & active transport - (definition and examples); gradient of

chemical potential as driving force in transport, equilibria and transport across membranes;

diffusion, osmosis, sedimentation, osmotic pressure. Donnan equilibrium, diffusion potential,

membrane potential. Channel protein and porins.

Unit 3: Cell cycle and cell division: [10 L]

Eukaryotic cycle definition and its regulation, phases of cell cycle, Cell division and its

significance, types of cell division, Mitosis and meiosis, different stages of cell division,

Page 6: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Unit 4: Cell signaling: [8 L]

Signaling molecules and their receptors. Function of cell surface receptors. Pathways of

intracellular receptors – Cyclic AMP pathway, cyclic GMP and MAP kinase pathway.

Component: Practical

1. Preparation of buffers. Concepts of molarity,molality

2. pH measurements

3. pH Titration of the Glycine HCl solution

4. RBC count using hemocytometer

5. DNA absorption spectra

6. Gram staining of bacteria

7. Estimation of blood glucose.

8. Assay of salivary amylase.

9. Isolation of lecithin, identification by TLC, and its estimation.

10. Estimation of protein and sugar.

Readings:

1. Principles of Biochemistry A. Lehninger.

2.Molecular Biology of the Cell B.Alberts et al.

Page 7: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: CC2 – Molecular Biology

Credit: 6 (4L-0T-2P)

Component: Theory

Module 1:

Unit 1: Forces in Biomolecules: [2 L]

Types of interaction between atoms, van der Waals interactions, Coulombic, dipole-dipole,

hydrophobic interaction, hydrogen bond.

Unit 2: Carbohydrates: [8 L]

Definition, classification and structural concept of: Monosaccharides: Hexoses (only Glucose),

Pentoses (Ribose, Ribulose, Xylose) Disaccharides: Sucrose, Lactose, Maltose Amino Sugars:

Glucosamine, Muramic Acid Inversion (hydrolysis) of cane sugar. Chemical reactions of

monosaccharides (glucose & fructose i.e., aldose and ketose) with HN03, Br2 - water, HI04,

Phenylhydrazine. Principle of chemical estimation of sugar. Anomeric effect (Methylation effect).

Polysaccharides: Chemical structure of Starch (αamylose, amylopectin), glycogen & cellulose.

Smith degradation and enzymichydrolosis of α-amylose & amylopectin.

Unit 2: Amino Acids: [6 L]

Definition, classification, structure, stereochemistry of amino acids; Physico-chemical properties

(Ionization & Biuret reaction) of amino acids. Amphoteric molecule, Zwitterion, pK values;

Isoelectric point, Electrophoresis. Separation of amino acids by-Ion-exchange, Gel filtration, Paper

Chromatography and Thin Layer Chromatography. Peptides: peptide bond, biologically important

peptides (glutathione, oxytocin-important functions).

Unit 3: Proteins: [6 L]

Classification (Primary, Secondary, Tertiary, Quaternary- definition, examples). Ramchandran

plot. Types of proteins: i) Fibrous (α -helix, β - sheet, e.g. collagen): definition and structure. ii)

Globular: definition & examples. iii) Simple proteins and conjugated protein: definition &

examples—physical denaturation and renaturation, Protein folding.

Unit 5: Lipids: [6 L]

Definition, nomenclature, classification - (simple, complex, derived lipids - structure & example)

phospholipids, glycolipids, - (structure, composition); Soap, surfactants, fatty acid. hydrolysis,

saponification, saponification number, I2 number, acetylation, acetyl number, volatile fatty acid

number - definition and related problems, Isomerism - cis-trans isomerism. Fatty acids: Saturated

(palmitic acid, stearic acid), unsaturated (oleic acid): Structure of free fatty acids. General chemical

reaction of fatty acids - esterification. Hydrogenation and halogenations

Page 8: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Module 2:

Unit 1: Nucleic acid: [8 L]

Purine, pyrimidine - definition and structure. Nucleoside, nucleotide: definition and structure.

DNA & RNA: Double helical structure. A-DNA, B-DNA & Z-DNA (structure and differences).

Chemical Properties: Hydrolysis (acid, alkali), enzymatic hydrolysis of DNA. General structure

and types of RNA (tRNA, mRNA, rRNA). Hyperchromic effect. Cot curve, Tm.

Unit 2: DNA Replication: [8 L]

Types and functions of DNA polymerases in Prokaryote and Eukaryote. Replication in prokaryote

and Eukaryote. Proof reading activity, 5’-> 3’ exonuclease activity, topoisomerase activity,

Telomeric DNA replication and Plasmid Replication-theta model, strand displacement model and

rolling circle model.

Unit 3: Transcription: [8 L]

Fine structure of prokaryotic and eukaryotic gene, structure and function of the promoters in

mRNA, rRNA, tRNA genes. RNA polymerases in prokaryote and eukaryote, types and function.

Transcription of mRNA, rRNA, and tRNA genes in Prokaryote and eukaryote. Post transcriptional

processing of mRNA – 5’capping, splicing (including different types), polyadenylation and RNA

editing.

Unit 4: Translation: [8 L]

Genetic code and Wobble hypothesis. T-RNA structure and function, Translation in prokaryote

and eukaryote. Post translational modifications.

Component: Practical

1. Study a representative plant and animal cell by microscopy.

2. Study of the structure of cell organelles through electronmicrographs.

3. Cytochemical staining of DNA –Feulgen.

4. Demonstration of the presence of mitochondria in striated muscle cells/ cheek epithelial

cell using vital stain Janus Green-B.

5. Study of polyploidy in Onion root tip by colchicine treatment.

6. Identification and study of cancer cells by photomicrographs.

7. Study of different stages of Mitosis.

8. Study of different stages of Meiosis by permanent slides.

9. Plasmolysis experiment.

10. Visualization of Biological Macromolecules by RasMol/Pymol/ymol

Page 9: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Readings:

1. Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, David

Morgan, Martin Raff, Keith Roberts, and Peter Walter.

2. The Cell: A Molecular Approach. Geoffrey M. Cooper, Robert E. Hausman.

3. Essential Cell Biology-Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander

D.Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter.

Page 10: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Second Semester

Course: CC3 – Bacteriology and Virology

Credit: 6 (4L-0T-2P)

Component: Theory

Module 1:

Unit 1: Morphology of Bacteria: [8 L]

Size and shape of bacteria, cell membrane, cell wall, outer membrane, Mesosomes, Slime layer

and capsule, bacterial flagella, chemotaxis, genetic material, vacuoles, storage granules,

ribosomes, endospores, plasmids, cytoskeletal elements. Different staining methods to observe

bacterial cells, Principle of Gram Staining.

Unit 2: Effect of environment upon bacteria: [6 L]

Effect of temperature, effect of ultra violet radiation, effect of osmotic pressure, effect of pH, effect

of surface tension, effect of oxygen.

Unit 3: Bacterial reproduction: [6 L]

Binary fission, conidia formation, cyst formation, budding, fragmentation, akinetes.

Unit 4: Bacterial growth and nutrition: [8 L]

Bacterial growth curve and its stages. Interpretation of growth curve, concept of generation time,

growth measurement techniques, Physical factors influencing growth - Temperature. pH, osmotic

pressure, salt concentration, bacterial nutrition, bacterial classification according to nutritional

requirements, Nutritional types (definition and example) - Photoautotrophs, Photoorganotrophs,

Chemolithotrophs (ammonia, nitrite, sulfur, hydrogen, iron oxidizing bacteria);

Chemoorganotrophs.

Unit 5: Antibiotic: [10 L]

Different methods to control bacterial growth. Discovery of antibiotic, characteristics of

antibiotics, Mode of action, cell wall inhibitors: Penicillins, Ampicillin, Cephalosporins,

Cycloserine, Bacitracin, Vancomycin, Cell membrane inhibitors: Polymyxins, Gramicidins,

Tyrocidines, nucleic acid and protein synthesis inhibitor: Streptomycin, Tetracyclines,

Chloramphenicol, Erythromycin. Antifungal antibiotics, Antitumor antibiotics, Development of

resistance to antibiotics, microbial assay of antibiotics.

Page 11: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Module 2:

Unit 1: Nature and Properties of Viruses: [10 L]

Introduction: Discovery of viruses, nature and definition of viruses, general properties, concept of

viroids, satellite viruses and Prions. Theories of viral origin. Structure of Viruses: Capsid

symmetry, enveloped and non-enveloped viruses. Isolation, purification and cultivation of viruses.

Viral taxonomy: Classification and nomenclature of different groups of viruses. Bacteriophages

Diversity, classification, one step multiplication curve, lytic and lysogenic phages (lambda phage)

concept of early and late proteins, regulation of transcription in lambda phage.

Unit 2: Viral Transmission and Replication: [12 L]

Modes of viral transmission: Persistent, non-persistent, vertical and horizontal. Salient features of

viral Nucleic acid: Unusual bases (TMV, T4 phage), overlapping genes (ɸX174, Hepatitis B virus),

alternate splicing (HIV), terminal redundancy (T4 phage), terminal cohesive ends (lambda phage),

partial double stranded genomes (Hepatitis B), long terminal repeats (retrovirus), segmented

(Influenza virus), and non-segmented genomes (picornavirus), capping and tailing (TMV). Viral

multiplication and replication strategies: Interaction of viruses with cellular receptors and entry of

viruses. Replication strategies of viruses as per Baltimore classification (phi X 174, Retroviridae,

Vaccinia, Picorna), Assembly with example of Polio virus and T4 phage, maturation and release

of virions.

Component: Practical

Preparation of different media: Synthetic Media, Complex media (Nutrient Agar,

McConkey agar).

Simple staining. Negative staining. Gram’s staining. Acid fast staining (permanent slide

only).

Capsule staining. Spore staining.

Isolation of pure cultures of bacteria by streaking method.

Serial dilution Estimation of CFU count by spread plate method/pour plate method.

cultivation, maintenance and preservation/ stocking of pure cultures;

Isolation and enumeration of bacteriophages (PFU) from water/sewage sample using

double agar layer technique.

Biochemical Characterization of Bacteria

Oxidation/Fermentation Test Catalase, Oxidase and Urease Tests IMViC test Hydrogen

Sulfide Test and Nitrate Reduction Test. Casein and Starch Hydrolysis

Isolation and characterization of plant microbes epiphytes

Preparation of RBC ghosts and determination of intrinsic proteins

Antibiotic assay.

Reading:

1. Fundamental Principles of Bacteriology by A.J. Salle

2. General Microbiology by R. Y. Stanier, Fifth edition.

3. Microbiology by M.J. Pelczar.

Page 12: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: CC4 – Bioenergetics and Metabolism

Credit: 6 (4L-0T-2P)

Component: Theory

Module 1:

Unit 1: Thermodynamics: [10 L]

Zero-th law, 1st law & 2nd law of thermodynamics: application in biological systems, Concept of

free energy, standard free energy change. Equilibrium constant; enthalpy; entropy; entropy: open

vs. dead cells, dissociation constant, protein unfolding, DNA denaturation, 1st order and second

order kinetics.

Unit 2: Enzymes: [10 L]

General properties, Nomenclature and classification; Co-factors definition and function with

special reference to the representative substances - a) Co-enzymes (NAD+, NADP+, Co-enzyme-

A, TPP, Pyridoxal phosphate); b) Prosthetic groups (FAD+ - Succinic dehydrogenase); c) Metal

ions: Zn2+, Mg2+, Fe2+, Fe3+, Mn2+ - required for enzyme action Enzyme Kinetics - Michaelis-

Menten equation; Enzyme Inhibition - Competitive-cite succinate on Malonate dehydrogenase as

example, Non-competitive - Cite lodoacetamide on triose phospate dehydrogenase and EDTA as

example; Suicide inactivation-action of penicillin on bacterial cell wall biosynthesis as an

example; Regulatory enzymes-Allosteric - Cite CTP on aspartate transcarbamylase as example;

Feedback inhibition - Cite Threonine to Isoleucine as example; Ribozyme (catalytic RNA) and

Abzyme (use of antibody as enzyme) - definition only.

Module 2:

Unit 1: Carbohydrate metabolism: [14 L]

Aerobic Respiration-Glycolysis (EMP-pathway) with energy production: entry of galactose &

fructose in EMP-path; TCA-cycle with energy production: pentose-phosphate pathway: Electron

Transport Chain (in brief) & ATP generation sites; ATP & ADP cycle (oxidationreduction

potential and electromotive force). Photophosphorylation, oxidative phosphorylation

(chemiosmotic theory); Anaerobic respiration - Utilizing NO2, Sulfur (SO4), CO2 as electron

acceptors; Stickland-reaction; Entner-Doudoroff pathway Fermentation - Glucose metabolism in

anaerobic condition general concept only Bacterial photosynthesis (Cyanobacteria and Green-

sulphur bacteria); Difference with eukaryotic photosynthesis.

Unit 2: Amino acid metabolism: [10 L]

Transamination, deamination, transmethylation and decarboxylation. Glucogenic and ketogenic

amino acids, Outline of Urea Cycle; Microbial metabolism of glycine, phenylalanine and lysine.

Page 13: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Unit 3: Purine and Pyrimidine metabolism: [8 L]

Synthesis of purines: elementary concept, source of the precursors of purines, ribose 5- phosphate;

synthesis of AMP and GMP from IMP-only preliminary idea; Importance of folic acid and target

of sulfonamides; Microbial reduction of purines to deoxy-purines: thioredoxine; Biosynthesis of

pyrimidines: Aspartate transcarbamoylase (ATCase); Origin of Thymine: importance of folic acid

(conceptual); Degradation of nucleotides: xanthines, uric acid; catabolites of pyrimidines: NAD

and Coenzyme A.

Unit 4: Lipid metabolism: [8 L]

Detailed account for oxidation of even-and odd-carbon numbered, saturated and unsaturated fatty

acids; Brief idea of fatty acid biosynthesis; Metabolism of Triglycerides and phospholipids.

Component:Practical

1. Study and plot the growth curve of E. coli by turbidometric method.

2. Calculations of generation time and specific growth rate of bacteria from the graph plotted

with the given data.

3. Effect of temperature on growth of E. coli.

4. Effect of pH on growth of E. coli.

5. Effect of salt concentration on growth of E. coli.

6. Effect of aeration on growth of E. coli.

7. Saponification number of oil.

Reading:

1. Lehninger Principles of Biochemistry.

2. Biochemistry by Stryer

3. Biochemistry by Voet and Voet.

Page 14: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Third Semester

Course: CC5 – Microbial Genetics

Credit: 6 (4L-0T-2P)

Component: Theory

Unit 1: DNA, gene and chromosome: [12 L]

Types of DNA sequences: repetitive and unique, Structure prokaryotics gene; genomic

organization in prokaryotes (nucleoid, DNA supercoiling, topoisomerases), Extrachromosomal

inheritance: Plasmids (genes found, copy number, compatibility). Episomes. Structure of

eucakryotic genes (description and experimental proofs), multigene family. Genome organization

(ARS, centromere, telomere, chromatin structure), various forms of repetitive DNA (satellite,

LINEs and SINEs), psedogenes. Extrachromosomal inheritance (mitochondria and plastids),

Nucleosome structure. Chromosome structure.

Unit 2: Transposones: [10 L]

Prokaryotic transposable elements – Insertion Sequences, composite and non-composite

transposons, Replicative and Non replicative transposition, Mu transposon Eukaryotic

transposable elements - Yeast (Ty retrotransposon), Drosophila (P elements), Maize (Ac/Ds) Uses

of transposons and transposition

Unit 3: Mutation and Repair: [12 L]

Spontaenous (Spontaneous mutation Luria - Delbruck's Fluctuation Test) and induced mutations,

Mutagenic agents - Physical, Chemical and Biological (Phage-mu). Genetic Techniques to detect

mutations in bacteria and fungi (isolation and characterization of nutritional auxotrophic

mutation); Different forms of mutations and how they arise (tautomeric shift, base analog,

alkylating agent, apurinic lesions, UV radiation and thymine dimers, replicational error); Ames

test is used the assess the mutagenecity of compounds. Repair: reversal of UV damage in

prokaryotes: photoreactivation, base excision and nucleotide excision repair, post replicational

repair, mismatch repair, SOS repair, error prone repair.

Unit 4: Bacterial Recombination: [14 L]

Transformation - Discovery, mechanism of natural competence Conjugation - Discovery,

mechanism, Hfr and F’ strains, Interrupted mating technique and time of entry mapping

Transduction - Generalized transduction, specialized transduction, LFT & HFT lysates, Mapping

by recombination and co-transduction of markers.

Unit 5: Operon system: [12 L]

Gene regulation and operon theory in prokaryotes, repressible operons, Inducible Operon, lac

operon, gal operon, trp operon,

Page 15: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Component: Practical

1. Preparation of Master and Replica Plates.

2. Study the effect of chemical (HNO2) and physical (UV) mutagens on bacterial cells.

3. Study survival curve of bacteria after exposure to ultraviolet (UV) light.

4. Isolation of Plasmid DNA from E.coli.

5. Study different conformations of plasmid DNA through Agaraose gel electrophoresis.

6. Demonstration of Bacterial Conjugation.

7. Demonstration of bacterial transformation and transduction.

8. Demonstration of AMES test.

Reading:

1. Watson JD, Baker TA, Bell SP et al. (2008) Molecular Biology of the Gene, 6th Ed., Benjamin

Cummings

2. Gardner EJ, Simmons MJ, Snustad DP (2008). Principles of Genetics. 8th Ed. Wiley-India

3. Russell PJ. (2009). i Genetics- A Molecular Approach. 3rd Ed, Benjamin Cummings

4. Sambrook J and Russell DW. (2001). Molecular Cloning: A Laboratory Manual. 4th Edition,

Cold Spring Harbour Laboratory press.

Page 16: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: CC6 – Recombinant DNA technology

Credit: 6 (4L-0T-2P)

Component: Theory

Unit 1: Molecular Cloning- Tools and Strategies: [10 L]

Cloning Tools; Restriction modification systems: Types I, II and III. Mode of action,

nomenclature, applications of Type II restriction enzymes in genetic engineering DNA modifying

enzymes and their applications: DNA polymerases. Terminal deoxynucleotidyl transferase,

kinases and phosphatases, and DNA ligases Cloning Vectors: Definition and Properties Plasmid

vectors: pBR and pUC series Bacteriophage lambda and M13 based vectors Cosmids, BACs,

YACs Use of linkers and adaptors Expression vectors: E. coli lac and T7 promoter-based vectors,

yeast YIp, YEp and YCp vectors, Baculovirus based vectors, mammalian SV40-based expression

vectors.

Unit 2: Methods in Molecular Cloning: [12 L]

Transformation of DNA: Chemical method, Electroporation, Gene delivery: Microinjection,

electroporation, biolistic method (gene gun), liposome and viralmediated delivery, Agrobacterium

- mediated delivery DNA, RNA and Protein analysis: Agarose gel electrophoresis, Southern - and

Northern - blotting techniques, dot blot, DNA microarray analysis, SDS-PAGE and Western

blotting.

Unit 3: DNA Amplification and DNA sequencing: [12 L]

PCR: Basics of PCR, RT-PCR, Real-Time PCR Sanger’s method of DNA Sequencing: traditional

and automated sequencing Primer walking and shotgun sequencing.

Unit 4: Construction and Screening of Genomic and cDNA libraries: [12 L]

Genomic and cDNA libraries: Preparation and uses, screening of libraries: Colony hybridization

and colony PCR, Chromosome walking and chromosome jumping.

Unit 5: Applications of Recombinant DNA Technology: [14 L]

Products of recombinant DNA technology: Products of human therapeutic interest - insulin, hGH,

antisense molecules. Bt transgenic - cotton, brinjal, Gene therapy, recombinant vaccines, protein

engineering and site directed mutagenesis.

Page 17: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Component: Practical

1. Preparation of competent cells for transformation.

2. Demonstration of Bacterial Transformation and calculation of transformation efficiency.

3. Digestion of DNA using restriction enzymes and analysis by agarose gel electrophoresis.

4. Ligation of DNA fragments.

5. Cloning of DNA insert and Blue white screening of recombinants.

6. Interpretation of sequencing gel electropherograms.

7. Designing of primers for DNA amplification.

8. Amplification of DNA by PCR.

9. Demonstration of Southern blotting.

Reading:

1. Brown TA. (2010). Gene Cloning and DNA Analysis. 6th edition. Blackwell Publishing,

Oxford, U.K.

2. Primrose SB and Twyman RM. (2006). Principles of Gene Manipulation and Genomics,

7th edition. Blackwell Publishing, Oxford, U.K.

Page 18: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Fourth Semester

Course: CC7 – Principles of Immunology

Credit: 6 (4L-0T-2P)

Component: Theory

Unit 1: Basic concept of immunology: [4 L]

Innate immunity, acquired immunity, humoral and cell-mediated immune response, B-cell and T-

cell.

Unit 2: Cells and Organs in immunology: [4 L]

Lymphoids cells, mononuclear cells, granulocytic cells, mast cells, dendritic cells, primary

lymphoid organs, lymphatic system, secondary lymphoid organs.

Unit 3: Antigen: [4 L]

Antigenicity and immunogenicity, Epitopes, properties of B-cell and T-cell epitopes, haptens and

mitogens.

Unit 4: Immunoglobulin: [4 L]

Basic structure of immunoglobulin, sequencing study, immunoglobulin fine structure, antigenic

determinants: isotypic, allotypic, idiotypic. Immunoglobulin classes, monoclonal antibodies.

Unit 5: Antigen antibody interaction: [6 L]

Antibody affinity, antibody avidity, cross- reactivity, precipitation reaction, agglutination reaction,

radioimmunoassay, ELISA, RIA, immunofluorescence.

Unit 6: Genetic recombination of immunoglobulin genes: [4 L]

Genetic model, multigene organization of immunoglobulin genes, variable region gene

rearrangements, class switching, regulation of immunoglobulin gene transcription.

Unit 7: Antigen processing and presentation: [6 L]

MHC molecules, antigen presenting cells, t-cell receptor, T-cell maturation, T-cell activation, T-

cell differentiation. Cytokines.

Unit 8: Compliment system: [6 L]

Compliment activation, classical pathway and alternative pathway, MAC formation.

Page 19: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Unit 9: Hypersensitivity: [4 L]

Different types of hypersensitive reactions. Type I, Type II, Type III and Type IV hypersensitivity.

Unit 10: Autoimmunity: [6 L]

Autoimmune diseases, Hashimoto’s thyroiditis, autoimmune anemia, Goodpasture’s syndrome,

Insulin dependent diabetes mellitus, graves diseases, myasthenia gravis, systemic lupus

erythematosus, multiple sclerosis, rheumatoid arthritis.

Unit 11: Vaccines: [4 L]

Active and passive immunization, whole-organism vaccines, recombinant vector vaccines, DNA

vaccines.

Unit 12: Cancer biology: [4 L]

Cause of cancer, symptoms, cure.

Unit 7: Chemotherapeutic agents: [4 L]

Uses of chemotherapeutic agents, dosage and toxicity, different classes of chemotherapeutic

agents, antiviral chemotherapeutic agents, synthetic chemotherapeutic agents, microbial

susceptibility to chemotherapeutic agents.

Unit 13: Plant Immunity: [4 L]

Disease resistance in plant, plant immune system, pattern-triggered immunity, effector-triggered

immunity, R gene and R proteins.

Component: Practical

1. Identification of human blood groups.

2. Perform Total Leukocyte Count of the given blood sample.

3. Perform Differential Leukocyte Count of the given blood sample.

4. Separate serum from the blood sample (demonstration).

5. Perform immunodiffusion by Ouchterlony method.

6. Perform DOT ELISA.

7. Perform immunoelectrophoresis.

8. Indirect/ Direct ELISA

9. Rocket electrophoresis test/ Immunoelectrophoresis

10. IgG digestion by papain/ pepsin

Page 20: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Reading:

1 Abbas AK, Lichtman AH, Pillai S. (2007). Cellular and Molecular Immunology.

6thedition Saunders Publication, Philadelphia.

2 Delves P, Martin S, Burton D, Roitt IM. (2006). Roitt’s Essential Immunology.

11thedition Wiley-Blackwell Scientific Publication, Oxford.

3 Goldsby RA, Kindt TJ, Osborne BA. (2007).

4 Kuby’s Immunology.6thedition W.H. Freeman and Company, New York.

Page 21: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: CC8 – Medical Microbiology and Drug Delivery

Credit: 6 (4L-0T-2P)

Component: Theory

Unit 1: Normal microflora of the human body and host pathogen interaction: [8 L]

Normal microflora of the human body: Importance of normal microflora, normal microflora of

skin, throat, gastrointestinal tract, urogenital tract Host pathogen interaction: Definitions -

Infection, Invasion, Pathogen, Pathogenicity, Virulence, Toxigenicity, Carriers and their types,

Opportunistic infections, Nosocomial infections. Transmission of infection, Pathophysiologic

effects of LPS.

Unit 2: Bacterial diseases: [8 L]

List of diseases of various organ systems and their causative agents. The following diseases in

detail with Symptoms, mode of transmission, prophylaxis and control Respiratory Diseases:

Streptococcus pyogenes, Haemophilusinfluenzae, Mycobacterium tuberculosis Gastrointestinal

Diseases: Escherichia coli, Salmonella typhi,Vibrio cholerae, Helicobacter pylori Others:

Staphylococcus aureus, Bacillus anthracis, Clostridium tetani, Treponema pallidum, Clostridium

difficie. Diphtheria, Tetanus, Cholera, Botulism, Listeriosis, Diarrhea, Tularemia, Brucellosis,

Neisserial disease, Staphylococcal disease, Streptococcal disease.

Unit 3: Viral diseases: [8 L]

List of diseases of various organ systems and their causative agents. The following diseases in

detail with Symptoms, mode of transmission, prophylaxis and control Polio, Herpes, Hepatitis,

Rabies, Dengue, AIDS, Influenza with brief description of swine flu, Ebola, Chikungunya,

Japanese Encephalitis.

Unit 4: Protozoan and fungal diseases: [8 L]

List of diseases of various organ systems and their causative agents. The following diseases in

detail with Symptoms, mode of transmission, prophylaxis and control, Malaria, Leishmaniasis.

Brief description of each of the following types of mycoses and one representative disease to be

studied with respect to transmission, symptoms and prevention, Cutaneous mycoses: Tinea pedis

(Athlete’s foot) Systemic mycoses: Histoplasmosis, Opportunistic mycoses: Candidiasis

Unit 5: Introduction to drugs and pharmacy: [8 L]

An overview and history of pharmaceutical industry. The business and the future of

Biopharmaceuticals. Drug regulation and control. Scope and applications of biotechnology in

pharmacy. Strategies for new drug discovery, finding a lead compound, combinatorial approaches

to new drug discovery, pre-clinical and clinical trials

Page 22: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Unit 6: Drug pharmacokinetics & pharmacodynamics: [8 L]

Routes of drug administration, membrane transport of drugs, absorption, distribution, metabolism

and excretion of drugs. Factors modifying drug action, mechanism of drug action on human beings,

receptor theory of drug action, pharmacogenomics, adverse effects of drugs and toxicology, Drug

interactions.

Unit 7: Drug Designing and delivery: [8 L]

Drug designing principles and methods, drug delivery techniques, liposomal method, nanoparticle

– mediated methods, drug targeting strategies,

Unit 8: Human – Microbe Coexistence: [4 L]

Microbes present in human gut and other parts of human body.

Component: Practical

1. Identify bacteria (any three of E. coli, Salmonella, Pseudomonas, Staphylococcus, Bacillus)

using laboratory strains on the basis of cultural, morphological and biochemical characteristics:

IMViC, TSI, nitrate reduction, urease production and catalase tests

2. Study of composition and use of important differential media for identification of bacteria: EMB

Agar, McConkey agar, Mannitol salt agar, Deoxycholate citrate agar, TCBS

3. Study of bacterial flora of skin by swab method

4. Perform antibacterial sensitivity by Kirby-Bauer method

5. Determination of minimal inhibitory concentration (MIC) of an antibiotic.

6. Study symptoms of the diseases with the help of photographs: Polio, anthrax, herpes, chicken

pox, HPV warts, AIDS (candidiasis), dermatomycoses (ring worms)

7. Study of various stages of malarial parasite in RBCs using permanent mounts.

8. Antibiotic Assay - Antimicrobial Sensitivity Test (Disc Diffusion Method)

9. Isolation of antibiotics producing bacteria.

10. Drug designing by computer software.

Reading:

Ananthanarayan R. and Paniker C.K.J. (2009) Textbook of Microbiology. 8th edition, University

Press Publication.

Page 23: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Fifth Semester

Course: CC9 – Eukaryotic Microbiology

Credit: 6 (4L-0T-2P)

Component: Theory

Unit 1: Protozoa: [8 L]

Introduction, structure and significance: Leishmania, Trichomonas, Entamoeba, Plasmodium,

cultivation of protozoa.

Unit 2: Algae: [8 L]

Distribution, morphology and classification (Smith) of Algae; Isolation from soil and water; algal

ecology, Media and methods used for culturing algae, measurement of algal growth, strain

selection and large scale cultivation, Symbiotic algae: Lichens, Coral reef and sea sponges.

Structure and reproduction of Spirogyra, Euglena, Exuviaella, Diatoms, Sargassam and Porphyra.

Unit 3: Biological and economic importance of algae: [4 L]

As primary producers and as commercial products [food, green energy (biofuel) and therapeutic

uses], heavy metal removal, immobilized and labeled algae; algal blooms and toxins.

Unit 4: Algal diversity from morphology to molecules: [8 L]

Importance of algae in production of algal pigments, biofuels, hydrogen production, important

bioactive molecules, role of algae in sustainable environment.

Unit 5: Fungi: [8 L]

Structure of Fungal cells and growth; Hyphae and non-motile unicells, motile cells, spores,

dormancy, growth of population and colonies, Mechanism of growth in Fungi, Measurement and

kinetics of growth, nutritional and environmental requirements; Prevention of fungal growth.

Heterothallism, parasexuality, sex hormones in fungi; physiological specialization, phylogeny of

fungi.

Unit 6: Fungal Systematics and Diversity: [8 L]

Implications of Molecular and Biochemical methods, rDNA analysis, RFLP, RAPD and other

fingerprinting techniques, fatty acids, polysachharides and lipids and role of secondary metabolites

in Systematics.

Unit 7: Mycorrhizal fungi: [8 L]

Diversity of endo and ectomycorrhizal fungi. Diversity of arbuscularmycorrhizal fungi. signaling,

penetration and colonization of roots, culturing and benefits and recent advances in the field of

mycorrhia.

Page 24: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Unit 8: Secondary metabolites from fungi: [8 L]

Terpenes, Non-robosomal peptides, hyrophobins, peptaibols, indole alkaloids, detailed emphasis

on poyketides.

Component: Practical

1. Isolation of fungus from soil.

2. Characterization of fungal colony isolated from soil.

3. Alcohol fermentation by yeast.

4. Observation of phytoplankton and zoo plankton from pond water.

Reading:

1. Fundamental Principles of Bacteriology by A.J. Salle.

2. Microbiology by M. J. Pelczar.

Page 25: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: CC10 – Industrial and Food Microbiology

Credit: 6 (4L-0T-2P)

Component: Theory

Module 1:

Unit 1: Isolation of industrially important microbial strains and fermentation media: [6 L]

Sources of industrially important microbes and methods for their isolation, preservation and

maintenance of industrial strains, strain improvement, Crude and synthetic media; molasses,

cornsteep liquor, sulphite waste liquor, whey, yeast extract and protein hydrolysates.

Unit 2: Fermentation processes: [8 L]

Types of fermentation processes - Solid-state and liquid-state (stationary and submerged)

fermentations; batch, fed-batch (eg. baker’s yeast) and continuous fermentations Components of a

typical bio-reactor, Types of bioreactors-Laboratory, pilot- scale and production fermenters,

constantly stirred tank and air-lift fermenters, Measurement and control of fermentation

parameters - pH, temperature, dissolved oxygen, foaming and aeration.

Unit 3: Down-stream processing: [4 L]

Cell disruption, filtration, centrifugation, solvent extraction, precipitation, lyophilization and

spray drying.

Unit 4: Production of industrial products: [10 L]

Citric acid, ethanol, penicillin, glutamic acid, Vitamin B12, Vinegar, Enzymes (amylase,

protease, lipase), wine.

Unit 5: Enzyme immobilization: [6 L]

Methods of immobilization, advantages and applications of immobilization, large scale

applications of immobilized enzymes.

Module 2:

Unit 1: Microbial spoilage of various foods: [8 L]

Principles, Spoilage of vegetables, fruits, meat, eggs, milk and butter, bread, canned Foods.

Unit 2: Principles and methods of food preservation: [8 L]

Principles, physical methods of food preservation: temperature (low, high, canning, drying),

irradiation, hydrostatic pressure, high voltage pulse, microwave processing and aseptic packaging,

Page 26: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

chemical methods of food preservation: salt, sugar, organic acids, SO2, nitrite and nitrates,

ethylene oxide, antibiotics and bacteriocins.

Unit 3: Fermented foods: [6 L]

Dairy starter cultures, fermented dairy products: yogurt, acidophilus milk, kumiss, kefir, dahi and

cheese, other fermented foods: dosa, sauerkraut, soy sauce and tampeh, Probiotics: Health benefits,

types of microorganisms used, probiotic foods available in market.

Unit 4: Design of Bioreactor: [4 L]

Component: Practical

1. MBRT of milk samples and their standard plate count.

2. Alkaline phosphatase test to check the efficiency of pasteurization of milk.

3. Isolation of any food borne bacteria from food products.

4. Isolation of spoilage microorganisms from spoiled vegetables/fruits.

5. Isolation of spoilage microorganisms from bread. 6. Preparation of Yogurt/Dahi.

6. Study different parts of fermenter

7. Microbial fermentations for the production and estimation (qualitative and quantitative) of:

(a) Enzymes: Amylase and Protease

(b) Amino acid: Glutamic acid

(c) Organic acid: Citric acid

(d) Alcohol: Ethanol

Reading:

1. Casida LE. (1991). Industrial Microbiology. 1st edition. Wiley Eastern Limited.

2. Patel A.H. (1996). Industrial Microbiology. 1st edition, Macmillan India Limited

3. Tortora GJ, Funke BR, and Case CL. (2008). Microbiology: An Introduction. 9th edition.

Pearson Education.

Page 27: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: CC11 – Bacterial Diversity

Credit: 6 (4L-0T-2P)

Component: Theory

Module 1:

Unit 1: Archaebacteria and Extremophilic bacteria: [6 L]

Characteristics of Archaebacteria, different classes of Archaebacteria, Methanogens: cell structure

and energy metabolism, Halophiles: cell structure and metabolism, Thermoacidophiles:

Sulfolobus, Thermoplasma and Thermoproteus group. Bacteria of extreme environments,

Thermophilic, Psycrophilic, Acidophilic, Alkaliphilic, Halophilic, Osmophilic, Barophilic,

Xerophilic, Radiorasistant and Hypolith.

Unit 2: Photosynthetic eubacteria: [4 L]

Cyanobacteria: Nitrogen fixation, anoxygenic photosynthesis, pigment synthesis, different groups

of Cyanobacteria, Purple bacteria: purple sulfur bacteria and purple non-sulfur bacteria, Green

bacteria: green sulfur bacteria and green non-sulfur bacteria.

Unit 3: Chemoautotrophic and Methophilic bacteria: [4 L]

Nitrifying bacteria, Sulfur oxidizers, Iron bacteria, Hydrogen bacteria, Carboxydobacteria,

Chemolithotrophic bacteria, Methophilic bacteria: metabolism and carbon assimilation,

methanotrophs and methylotrophs.

Unit 4: Gram negative aerobic and anaerobic bacteria: [4 L]

Aerobic Pseudomonads, Rhizobium group, Prosthecate bacteria, Azotobacter group, Acetic acid

bacteria, Sheathed bacteria, Spirillum group. Gram negative fermentative bacteria: Fumarate

respiration, Nitrate respiration, different groups of Gram negative anaerobic bacteria.The

Spirochetes, The Rikettsias, The Chlamydias.

Unit 5: Gliding eubacteria, Endospores forming bacteria and The Mollicutes: [6 L]

Myxobateria, Cytophaga group, Filamentous gliding chemoheterotrophs. The aerobic spore

forming bacteria and the anaerobic spore forming bacteria. Cellular structure, reproduction,

metabolism, Mycoplasma, Acholeplasma, Spiroplasma, Anaeroplasma, Ureaplasma.

Unit 8: The Actinomycetes: [4 L]

Characteristics of Actinomycetes: Motility, cell wall structure, mycelia actinomycetes, major

groups of actinomycetes.

Page 28: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Module 2:

Unit 1: Microbial Interactions: [4 L]

Microbe interactions: Mutualism, synergism, commensalism, competition, amensalism,

parasitism, predation, Microbe-Plant interaction: Symbiotic and non-symbiotic interactions,

Microbe-animal interaction: Microbes in ruminants,nematophagus fungi and symbiotic

luminescent bacteria.

Unit 2: Biogeochemical Cycling: [6 L]

Carbon cycle: Microbial degradation of cellulose, hemicelluloses, lignin and chitin, Nitrogen

cycle: Nitrogen fixation, ammonification, nitrification, denitrification and nitrate reduction,

Phosphorus cycle: Phosphate immobilization and solubilisation Sulphur cycle: Microbes involved

in sulfur cycle, Other elemental cycles: Iron and manganese.

Unit 3: Soil microbiology: [8 L]

Introduction to Soil microbiology, Properties of soil (Structure, texture, formation). Types and

significance of soil microbes, Bacteria, Fungi, Actinomycetes, Algae, Protozoa, Nematode and

Viruses, Factors affecting microbial population, Rhizosphere and Mycorrhizae, Interaction of

microbes, insects and rumen.

Unit 4: Air microbiology: [6 L]

Microbiology of air, Aeromicrobial pathways, Enumeration of bacteria from air, Air sampling

devices, Air sanitation, Air borne diseases.

Unit 5: Water microbiology: [8 L]

Microbiology of water, Potability of water quality, Indicator organisms, water purification,

waterborne diseases and their control measures, Microbiology of sewage, chemical and

biochemical characteristics of sewage, BOD & COD, Sewage treatment, Physical, chemical and

biological (trickling filter, activated sludge and oxidation pond) treatment, Disposable of wastes.

Component: Project

A project work should be done individually or in a group under the guidance of one faculty of

Microbiology department on Bacterial diversity after one Educational tour to any place of India.

The duration of tour will be at least 3-5 days at the spot depending upon the information/sample

collection of project work. The work will be documented & also presented by the candidate in

front of externals in a seminar.

Reading:

1. General Microbiology by R. Y. Stanier, Fifth edition.

2. Fundamental principles of bacteriology by A.J. Salle.

Page 29: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Sixth Semester

Course: CC12 – Sum-up course

Credit: 6 (4L-0T-4P)

Component: Theory

This course includes a sum-up of all core courses from last five semesters and an overall revision

will be offered to the students. Students may also have the opportunity to choose a specific unit

among the following list of units to emphasize on. They will be given special attention and training

for the chosen course. Students will be encouraged to write a review article, seminar presentation

and industrial interaction. Lecture hours will be distributed according to the selection of courses

by the student.

Unit 1: Biological macromolecules and their metabolism.

Unit 2: Central dogma and genetic information flow.

Unit 3: Bacterial cell structure and function, their interaction with human; pathogenicity and

diseases.

Unit 4: Immunology and medical approaches to fight against diseases.

Unit 5: Microbial genetics and recombinant DNA technology.

Unit 6: Microbial diversity in the environment.

Unit 7: Drug discovery, drug designing and drug delivery.

Page 30: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: CC13 – Microbiology Project

Credit: 12 (0L-0T-24P)

Component: Project

A research project work should be done individually under the guidance of one faculty of

Microbiology department at SNU or anywhere else on any topic related to the subject & can be

recorded as dissertation & also be presented by the candidate in front of external and internal

examiners in a seminar.

Page 31: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

DISCIPLINE SPECIFIC

ELECTIVES (DSE)

Page 32: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: DSE1 – Fundamentals of Chemistry

Credit: 6 (4L-0T-4P)

Component: Theory

Unit 1: Inorganic Chemistry I

Periodicity and Atomic Structure:

Development of Periodic Table, Light and Electromagnetic spectrum, Particle-like properties of

Electromagnetic Radiation: The Planck Equation, Wave-like properties of matter: The de Broglie

Equation,

Study of matter – its properties and behavior; Atomic Structure: Discovery of Electron by J J

Thomson, Bohr’s Theory, De Broglie Hypothesis, Heisenberg’s Uncertainty Principle.

Wave Functions and Quantum Numbers, The Shapes of Orbitals: s, p, d, f; Electron Configurations

and Periodic Table.

Unit 2: Organic Chemistry I

Organic Compounds: Structure and Bonding:

Classification and Nomenclature. Hybridization of orbitals and types of hybridization; Influence

of hybridization on bond properties; Shapes of molecules: methane, ethane, ethylene, acetylene,

water and carbon dioxide; Important bond parameters: Bond Length, Bond Angles, Bond Energy

Electronic Displacements and Polarity of bonds: Inductive, resonance, electromeric, mesomeric, hyperconjugation effects, H-bond and their

applications; Dipole moment.

Mechanism of organic reactions: Curved Arrow notation, drawing electron movements with arrows, half-headed and double headed

arrows, hemolytic and heterolytic bond breaking.

Types of organic reactions: substitution, addition, elimination, rearrangement

Types of reagents: electrophiles and nucleophiles

Reactive intermediates and their relative stability: Carbocations, Carbanions, Free radicals and

Carbenes

Unit 3: Physical Chemistry I

Concepts of Molarity, Molality and Normality

Thermodynamics-I: Intensive and extensive variables; state and path functions; isolated, closed and open

systems; Zeroth Law of Thermodynamics.

First Law of Thermodynamics: Work, Heat, Internal Energy, Heat Capacity, Concept of Enthalpy

H; Cp, Cv and their relation; calculations of q, w, U and H for reversible, irreversible and free

expansion of gases (ideal and van der Waals) under isothermal and adiabatic conditions.

Page 33: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Chemical Kinetics-I: Introduction to Rate law, order and molecularity; advancement of a reaction; differential and

integrated form of rate expressions up to second order reactions; Determination of order of a

reaction; Opposing reactions, consecutive reactions and parallel reactions

Conductance-I: Conductance and measurement of conductance; cell constant, specific and equivalent conductance,

molar conductance

Electrochemistry-I: Oxidation/reduction of ions based on half-cell potentials; Chemical cells, reversible and

irreversible cells; Electromotive force of a cell and its measurement, Nernst equation.

Ionic Equilibria: Strong, moderate and weak electrolytes; degree of ionization; factors affecting degree of

ionization; ionization constant and ionic product of water. Ionization of weak acids and bases;

Concept of pH, pKa, pKb; common ion effect; Salt hydrolysis-calculation of hydrolysis constant;

degree of hydrolysis and pH for different salts; Buffer solutions; Solubility and solubility product

of sparingly soluble salts – applications of solubility product principle.

Component: Practical

1. pH measurements, buffer preparation and Molarity Concept of different compounds:

pH Range: 4-5.6: sodium acetate/acetic acid buffer

pH Range: 7: di-sodium hydrogen phosphate/ mono- sodium hydrogen phosphate

pH Range: 9-10.8: sodium carbonate/sodium bi carbonate

2. Fun with Magic ink by NaHCO3

3. Different food colors analysis by spectrophotometer by Estimation of absorption maxima

4. Basics of chromatography

5. Strength comparison of different stomach antacids (active ingradients)

6. General acid base titration with suitable indicator

Reference Books:

1. Chemistry, 4th Edition by McMurry, J. and Fay, R.C., 2004, Pearson.

2. Organic Chemistry, 8th Edition by Leroy G. Wade, Junior, Pearson.

3. Physical Chemistry, P. Atkins and J. De Paul, 8th Edition (2006), International Student Edition,

Oxford University Press.

4. Basic Inorganic Chemistry, F. A Cotton, G. Wilkinson, and Paul L. Gaus, 3rd Edition (1995),

John Wiley & Sons, New York.

5. Chemistry for Degree Students, R. L. Madan, ISBN: 978-81-219-3230-1, S. Chand Publishing.

Page 34: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: DSE2 – Biosafety and Bioethics

Credit: 2 (2L-0T-0P)

Component: Theory

OBJECTIVES - This course will create awareness on the Biosafety and bioethics of

biotechnological processes.

Unit 1: Biosafety-Regulatory framework for GMOS in India

Regulatory framework in India governing GMOs-Recombinant DNA Advisory Committee

(RDAC), Institutional Biosafety Committee (IBC), Review Committee on Genetic Manipulation,

Genetic Engineering Approval Committee (GEAC), State Biosafety Coordination Committee

(SBCC), District Level Committee (DLC). Recombinant DNA Guidelines (1990), Revised

Guidelines for Research in Transgenic Plants (1998), Seed Policy (2002), Prevention Food

Adulteration Act (1955), The Food Safety and Standards Bill (2005), Plant Quarantine Order

(2003), Regulation for Import of GM Products Under Foreign Trade Policy (2006-2007), National

Environment Policy (2006). Rules for the manufacture, use/import/export and storage of hazardous

microorganisms/genetically engineered organisms or cells (Ministry of Environment and Forests

Notification, 1989).

Unit 2: Biosafety-Regulatory Framework for GMOS at International Level.

Convention of Biological Diversity (1992) – Cartagena Protocol on Biosafety – Objectives and

salient features of Cartagena Protocol – Advanced Information Agreement (AIA) procedure –

procedures for GMOs intended for direct use-risk assessment-risk management-handling,

transport, packaging and identification of GMOs-Biosafety Clearing House-unintentional

transboundary movement of GMOs-Benefits of becoming a party to the Cartagena Protocolstatus

of implementation in India.

Unit 3: Bioethics

What is bioethics? The legal and socioeconomic impacts of Biotechnology-Public education of

the process of biotechnology involved in generating new forms of life for informed decision-

making – ethical concerns of biotechnology research and innovation.

Unit 4: IPR and Patents:

Text/ Reference Books

1. Sasson A, Biotechnologies and Development, UNESCO Publications.

2. Singh K, Intellectual Property rights on Biotechnology, BCIL, New Delhi

3. Regulatory Framework for GMOs in India (2006) Ministry of Environment and Forest,

Government of India, New Delhi

4. Cartagena Protocol on Biosafety (2006) Ministry of Environment and Forest, Government of

India, New Delhi

Page 35: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: DSE3 – Bioinstrumentation Techniques

Credit: 4 (3L-1T-0P)

Component: Theory

Unit 1: Spectrophotometry:

Concept of electromagnetic radiations - UV, visible, IR. Orbital theory: Bonding and antibonding;

simple association of 1t orbital to form TT orbitals. Concept of chromophore - Wit's chromophore

theory, auxochorome, red shift, blue shift, Lambert-Beer's law - derivation & deviation;

absorptivity, line diagram & working principle of spectophotometer. Extinction co-efficient.

Instrumentation and application of UV and visible spectrophotometry, Light Scattering,

fluorescence spectroscopy, fluorescence energy transfer, NMR Spectroscopy, infrared

spectroscopy, CD spectroscopy.

Unit 2: X-ray crystallography:

X-ray diffraction, concept of different crystal structure, determination of crystal structure, Bragg

equation, reciprocal lattice, miller indices and unit cell.

Unit 3: Centrifugation:

Basic principle, relative centrifugal force (RCF), sedimentation and sedimentation co-efficient,

low and high speed centrifugation, Ultra centrifuge, preparative centrifugation, differential

centrifugation, density gradient centrifugation. Different types of rotors,

Unit 4: Chromatography:

Basic principle, paper chromatography, thin-layer chromatography, column chromatography,

absorption chromatography, Gas chromatography, ion-exchange chromatography, affinity

chromatography, high performance liquid chromatography, hydroxyapatite chromatography.

Unit 5: Electrophoresis:

Migration of an ion, factors affecting electrophoretic mobility, free electrophoresis, paper

electrophoresis, cellulose acetate electrophoresis, gel electrophoresis, two-dimensional gel

electrophoresis, pulse-field gel electrophoresis, capillary electrophoresis.

Unit 6: Microscope:

Microscope discovery, basic design of Microscope, Principle of Microscopy, Different

components of light waves, Resolving power; Numerical aperture, Chromatic Aberration, types of

Microscopes: light microscope, bright-field, dark-field, phase-contrast, invert microscope,

confocal microscope, fluorescent microscope, electron microscope (TEM and SEM).

Page 36: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: DSE4 – Essential Physics

Credit: 6 (4L-0T-4P)

Component: Theory

Module 1: General Properties of Matter

Unit 1: Elasticity: Continuum model of matter: Elastic properties, Hooke’s law, Flexural rigidity:

bending of beams loaded at the centre.

Unit 2: Surface Tension: Molecular model of matter: Surface Tension, Surface energy, the angle

of contact between surfaces, capillary phenomena, excess pressure on a curved liquid membrane,

dependence of surface tension on external factors.

Unit 3: Fluid Dynamics and Viscosity: Ideal fluids: Streamlines and flowlines, equations of

continuity, Euler’s equation of motion, streamline flow, Bernoulli’s equation and its application.

Newtonian and non-Newtonian fluids, coefficient of viscosity, critical velocity, Reynold’s

number.

Module 2: Elements of Modern Physics

Unit 1: Brief introduction to Quantum Mechanics: The limitations of existing theories of

blackbody radiation: Planck’s hypothesis and its successes, Einstein’s explanation of the

photoelectric effect – validation of the quantum nature of radiation (photon). Existence of discrete

energy states within atoms: Franck and Hertz experiments, De Broglie’s explanation. Classical vs.

Quantum Particles.

Unit 2: Nuclear Physics & Radioactivity: Nuclear Structure, Nuclear radioactivity: Alpha, Beta

and Gamma emissions. Alpha decay and spontaneous fission, nuclear reactions.

Unit 3: Laser Physics: Spontaneous and stimulated emission. Einstein’s A and B coefficients.

Basic components of a laser: active medium, optical resonator, pumping source. Threshold

condition for oscillation. Different types of laser and their operational principles.

Unit 4: Fiber Optics: Advantages of glass fibres. The coherent bundle. Numerical aperture. Ray

propagation in step-index and graded-index fibers. Effect of material dispersion. Multimode fibers

and single mode fibers.

Component: Practical

1. Young’s modulus.

2. Modulus of Rigidity.

3. Determination of viscosity of liquid by Stoke’s method.

4. Measurement of Planck’s constant using black body radiation and photo-detector.

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5. Photo-electric effect: photo current versus intensity and wavelength of light; maximum energy

of photo-electrons versus frequency of light.

6. To determine work function of material of filament of directly heated vacuum diode.

7. To determine (1) wavelength and (2) angular spread of diode laser using plane diffraction

grating.

8.To study the power-current characteristics of a diode laser.

References:

1. General Properties of Matter, Newman and Searle

2. Classical Mechanics and General Properties of Matter, D.P.Roychowdhuri and S.N.Maiti 3. Elements of Properties of Matter, D. S. Mathur.

4. Concepts of Modern Physics, A.Beiser

5. Introduction to Atomic and Nuclear Physics, Semat and Albright, Springlink

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Course: DSE5 – Biostatistics and Bioinformatics

Credit: 6 (4L-0T-2P)

Component: Theory

Module 1:

Unit 1:

Types of Data, Collection of data; Primary & Secondary data, Classification and Graphical

representation of Statistical data.Measures of central tendency and Dispersion. Measures of

Skewness and Kurtosis.

Unit 2:

Probability classical & axiomatic definition of probability, Theorems on total and compound

probability), Elementary ideas of Binomial, Poisson and Normal distributions.

Unit 3:

Methods of sampling, confidence level, critical region, testing of hypothesis and standard error,

large sample test and small sample test. Problems on test of significance, t-test, chi-square test for

goodness of fit and analysis of variance (ANOVA).

Unit 4:

Correlation and Regression.Emphasis on examples from Biological Sciences. Basic introduction

to Multivariate statistics. Curve fitting.

Unit 5:

R Programing.

Module 2:

Unit 1: Introduction to Bioinformatics and Biological Databases:

Biological databases - nucleic acid, genome, protein sequence and structure, gene expression

databases, Database of metabolic pathways, Mode of data storage - File formats - FASTA,

Genbank and Uniprot, Data submission & retrieval from NCBI, EMBL, DDBJ, Uniprot, PDB.

Unit 2: Sequence Alignments, Phylogeny and Phylogenetic trees:

Local and Global Sequence alignment, pairwise and multiple sequence alignment. Scoring an

alignment, scoring matrices, PAM & BLOSUM series of matrices Types of phylogenetic trees,

Different approaches of phylogenetic tree construction - UPGMA, Neighbor joining, Maximum

Parsomony, Maximum likelihood.

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Unit 3: Protein Structure Predictions:

Protein 3D modeling by web based server.

Component: Practical

1. Isolation of protein by column chromatography.

2. DNA gel electrophoresis

3. Protein gel electrophoresis.

4. Cellular fractionation by centrifugation.

5. Sequence retrieval from NCBI in FASTA format.

6. Performing BLAST

7. Drawing of phylogenetic tree and its analysis

8. Protein structure viewing by Rasmol.

9. Molecular structure design by Avogadro.

10. Validation of Protein 3D model.

11. Statistical Analysis by “R”.

Reading:

1. Biophysical chemistry by Upadhyay, Upadhyay and Nath.

2. Bioinformatics by Lesk

3. Bioinformatics by Attwood.

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GENERIC ELECTIVES (GE)

Page 41: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

COURSES OFFERED BY DIFFERENT DEPARTMENTS AS GENERAL ELECTIVE

SUBJECT FOR UNDER GRADUATE STUDENTS

DEPARTMENT COURSE

ENGLISH

THE STUDY OF SCRIPTS (FOR ODD SEMSTER)

TRANSLATION STUDIES (FOR EVEN

SEMESTER)

COMPUTER SCIENCE BASICS OF COMPUTER SCIENCE (FOR FIRST

SEMESTER)

DATA STRUCTURE (FOR 4TH SEMESTER)

OBJECT ORIENTED PROGRAMMING (FOR 5TH

SEMESTER)

DATABASE MANAGEMENT SYSTEMS (DBMS)

(FOR 6TH SEMESTER)

BIOTECHNOLOGY BIOTECHNOLOGY IN HUMAN WELFARE (FOR

ODD SEMESTER)

FUNDAMENTALS OF DEVELOPMENTAL

BIOLOGY (FOR EVEN SEMESTER)

MASS COMUNICATION AND JOURNALISM BASICS OF JOURNALISM (FOR ODD SEMESTER)

SCIENTIFIC REPORT WRITING AND EDITING

(FOR EVEN SEMESTER)

HOSPITALITY AND TOURISM

ADMINISTRATION

HOSPITALITY & TOURISM

ENTREPRENEURSHIP (FOR ODD SEMESTER)

PERSONALITY DEVELOPMENT (FOR EVEN

SEMESTER)

MICROBIOLOGY

MOLECULAR SECRETS OF LIFE (FOR ODD

SEMESTER)

INTRODUCTION TO FORENSIC SCIENCE (FOR

EVEN SEMESTER)

ECONOMICS

ECONOMIC HISTORY OF INDIA (FOR ODD

SEMESTER)

ECONOMIC DEVELOPMENT (FOR EVEN

SEMESTER)

CHEMISTRY FUNDAMENTALS OF CHEMISTRY(FOR ODD

SEMESTER)

STEREOCHEMISTRY AND CONFORMATION

(FOR EVEN SEMESTER)

PHYSICS

WHERE DO YOU LIVE? A JOURNEY THOUGH

OUR GORGEOUS UNIVERSE (FOR ODD

SEMESTER)

HISTORY AND PHILOSOPHY OF SCIENCE

MANAGEMENT

ORGANIZATIONAL BEHAVIOR (FOR ODD

SEMESTER)

BUSINESS STRATEGY (FOR EVEN SEMESTER)

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DEPARTMENT: ENGLISH

COURSE: GE – THE STUDY OF SCRIPTS (FOR ODD SEMSTER)

1. Course Objectives:

This course intends to acquaint the students with the ancient scripts of the bronze as well as the iron

age civilizations that are awaiting decipherment, especially the Linear A and B scripts, the

enigmatic Indus Valley Civilization Script (IVCS), the Rongorongo script and the Egyptian script

that however, has been deciphered. It will trace the history of the study of these scripts and shall

look into the modern computational methods and the latest discoveries in the field of

computational and cognitive linguistics that have been used to study them.

2. Course Outcomes:

After taking this course, students are expected to gain an understanding of the basic orthography as

well as the real problems that lie in the path of decipherment of the same and also understand the

various research methods employed to study them.

Unit I: The History of Language Decipherment:

Decipherment and the underlying theory, first and second order language, the concept of underlying

language, famous linguists, structuralism and structural linguistics, Chomsky and the cognitive

revolution, ethnography, archaeology and the study of scripts.

Unit II: Scripts: An Introduction

Linear A and B, Rongorongo, IVC, Egyptian.

Unit III: The Indus Valley Script—Detailed Study

Problems posed by short inscriptions and orthography, the proto-Dravidian Hypothesis, Iravathan

Mahadevan’s concordance of the IVC signs, Asko Parpola and his hypothesis, Nisha Yadav’s and

Rajesh Rao’s observations, the study of select seals from Dholavira and Harappa, the Dholavira

sign board, the possible reasons for the decline of the script, IVC painted pottery, the

‘Pashupatinath’ seal, the dancing girl and female iconography, trade practices and the IVC script,

the anti-literate hypothesis: S. Farmer et al. , animal figurines in the seals, seals found in

Mesopotamia: issues.

Unit IV: Modern techniques to study the IVC script:

The idea of conditional entropy, recent advances in computational linguistics, the use of sound

silencing, AI and decipherment, the Chennai team and deep neural networks, efforts in IIT

Kharagpur to understand the disappearance of the civilization and the script through climate

modelling simulation, other relevant techniques.

Select Readings:

1) Robinson, Andrew, Lost Languages: The Enigma of World’s Undeciphered Scripts. New York:

Mac-Graw-Hill, 2005.

2) Shendge, Malati J, Unsealing the Indus Script: Anatomy of its Decipherment. New Delhi:

Atlantic, 2010.

3) Yule, George, The Study of Language. New Delhi: CUP, [2007?].

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COURSE: GE – TRANSLATION STUDIES (FOR EVEN SEMESTER)

1. Course Objectives:

After taking this course, the students are expected to understand the nuances of translation and the act

of transcreation itself that often takes into account the fact that the translator has to possess a sound

understanding of both the language and the general vocabulary of the target text and the source

text.

2. Course Outcomes:

After going through the course, the students are expected to understand the theory and the praxis of

the very enterprise of transcreation.

Unit I: Transcreation: Theory and History

The history of translation and the emergence of translation studies, translation as a discipline in ancient

Greece and Rome, translation in India, the theory of translation, translation or transcreation?

Unit II: Translation: Issues at Work

Translation and the issue of vocabulary, the ‘loss’ of meaning during the act of translation, ‘good’ and

‘bad’ translation, the issue of copyright © in translation, translation as a profession.

Unit III: Transcreation : Practice 1

Translating from select texts into English (from Bengali to English and Hindi to English and vice

versa).

Unit IV: Transcreation: Practice 2

The concept of computer/ machine translation and the use of software and translation blogs and

services.

Select Readings:

Munday, Jeremy. Introducing Translation Studies: Theories and Applications. New York; London:

Routledge, 2012.

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DEPARTMENT: COMPUTER SCIENCE

COURSE: GE – BASICS OF COMPUTER SCIENCE (FOR FIRST SEMESTER)

Unit 1: Data representation (4 Lectures):

Data vs Information: Bit, byte number system: binary, octal, hexadecimal, 1’s, 2’s complement

arithmetic, digital logic: AND, OR etc.

Unit 2: General problem Solving concepts (6 Lectures):

Algorithm and Flowchart for problem solving with Sequential Logic Structure, Decisions and

Loops, time & space complexity; Imperative languages: Introduction to imperative language;

syntax and constructs of a specific language (ANSI C).

Unit 3: Human Computer Interface: (7 Lectures):

Types of software, operating system as user interface, utility programs; Computing systems:

hardware & software, Architecture & organization history: von Neumann Architecture: memory,

processor, I/O; BIOS, Booting, Application software, system software, introduction of

programming languages: brief overview of Pascal, FORTRAN, and BASIC.

Unit 4: Devices:(6 Lectures):

Input and output devices (with connections and practical demo), keyboard, mouse, joystick,

scanner, OCR, OMR, bar code reader, web camera, monitor, printer, plotter Memory: Primary,

secondary, auxiliary memory, RAM, ROM, cache memory, hard disks, optical disks.

Unit 5: Computer Organisation and Architecture: (5 Lectures):

C.P.U., registers, system bus, main memory unit, cache memory, Inside a computer, SMPS,

Motherboard, Ports and Interfaces, expansion cards, ribbon cables, memory chips, processors.

Unit 6: Overview of Emerging Technologies: (4 Lectures)

Bluetooth, cloud computing, big data, data mining, mobile computing and embedded systems.

Unit 7: Use of Computers in Education and Research: (4 Lectures)

Data analysis, Heterogeneous storage, e-Library, Google Scholar, Domain specific packages such

as SPSS, Mathematica etc.

Reference Books: 1. A. Goel, Computer Fundamentals, Pearson Education, 2010.

2. P. Aksoy, L. DeNardis, Introduction to Information Technology, Cengage Learning, 2006

3. P. K.Sinha, P. Sinha, Fundamentals of Computers, BPB Publishers, 2007.

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COURSE: GE – DATA STRUCTURE (FOR 4TH SEMESTER)

(36 LECTURES); L-T-P: 3-0-2

Module 1: (8 Lectures)

Introduction: Basic Terminologies: Elementary Data Organizations, Data Structure

Operations: insertion, deletion, traversal Searching: Linear Search and Binary Search

Techniques and their complexity analysis.

Module 2: (10 Lectures)

Stacks and Queues: ADT Stack and its operations: Algorithms and their complexity

analysis, Applications of Stacks: Expression Conversion and evaluation – corresponding

algorithms and complexity analysis. ADT queue, Types of Queue: Simple Queue, Circular

Queue, Priority Queue; Operations on each types of Queues

Module 3: (10 Lectures)

Linked Lists: Singly linked lists: Representation in memory, Algorithms of several

operations: Traversing, Searching, Insertion into, Deletion from linked list; Linked

representation of Stack and Queue, Header nodes, Doubly linked list

Trees: Basic Tree Terminologies, Different types of Trees: Binary Tree, Threaded Binary

Tree, Binary Search Tree, AVL Tree; Tree operations on each of the trees

Module 4: (10 Lectures)

Sorting and Hashing: Objective and properties of different sorting algorithms: Selection

Sort, Bubble Sort, Insertion Sort, Quick Sort, Merge Sort, Heap Sort;

Suggested books:

1. “Fundamentals of Data Structures”, Illustrated Edition by Ellis Horowitz, Sartaj Sahni,

Computer Science Press.

Suggested reference books:

1. Algorithms, Data Structures, and Problem Solving with C++”, Illustrated

Edition by Mark Allen Weiss, Addison-Wesley Publishing Company

2. “How to Solve it by Computer”, 2nd Impression by R. G. Dromey, Pearson

Education.

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COURSE: GE – OBJECT ORIENTED PROGRAMMING (FOR 5TH SEMESTER)

(30 Lectures); L-T-P: 3-0-2

Module 1: Abstract data types and their specification. How to implement an ADT. Concrete state

space, concrete invariant, abstraction function. Implementing operations, illustrated by the Text

example. Features of object-oriented programming. Encapsulation, object identity, polymorphism

– but not inheritance. Inheritance in OO design. [10L]

Module 2: Design patterns. Introduction and classification. The iterator pattern. Model-view-

controller pattern. Commands as methods and as objects. Implementing OO language features.

Memory management. Generic types and collections [12L]

Module 3: The software development process. The concepts should be practised using Java. [8L]

Suggested books

1. Barbara Liskov, Program Development in Java, Addison-Wesley, 2001

Suggested reference books

1. Any book on Core Java 2. Any book on C++

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COURSE: GE – DATABASE MANAGEMENT SYSTEMS (DBMS) (FOR 6TH

SEMESTER)

(36 Lectures); L-T-P: 3-0-2

Module 1: (10L)

Database system architecture: Data Abstraction, Data Independence, Data Definition Language

(DDL), Data Manipulation Language (DML). Data models: Entity-relationship model, network

model, relational and object oriented data models, integrity constraints, data manipulation

operations.

Module 2: (10L)

Relational query languages: Relational algebra, Tuple and domain relational calculus, SQL3, DDL

and DML constructs, Open source and Commercial DBMS - MYSQL, ORACLE, DB2, SQL

server. Relational database design: Domain and data dependency, Armstrong's axioms, Normal

forms, Dependency preservation, Lossless design. Query processing and optimization: Evaluation

of relational algebra expressions, Query equivalence, Join strategies, Query optimization

algorithms.

Module 3: (6L)

Storage strategies: Indices, hashing.

Module 4: (10L) Transaction processing: Concurrency control, ACID property, Serializability of

scheduling, Locking and timestamp based schedulers, Multi-version and optimistic Concurrency

Control schemes, Database recovery.

Suggested books:

1. “Database System Concepts”, 6th Edition by Abraham Silberschatz, Henry F. Korth, S.

Sudarshan, McGraw-Hill.

Suggested reference books:

1 “Principles of Database and Knowledge – Base Systems”, Vol 1 by J. D. Ullman, Computer

Science Press.

2 “Fundamentals of Database Systems”, 5th Edition by R. Elmasri and S. Navathe, Pearson

Education 3 “Foundations of Databases”, Reprint by Serge Abiteboul, Richard Hull, Victor Vianu,

Addison-Wesley

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DEPARTMENT: BIOTECHNOLOGY

COURSE: GE – BIOTECHNOLOGY IN HUMAN WELFARE (FOR ODD SEMESTER)

PURPOSE

The course will provide a basic knowledge of applications of Biotechnology in industrial and

medical fields

Unit 1: Environmental Biotechnology

Water and waste water treatment process: Current community drinking water treatment process

disinfection of water (chlorination and ozonation), primary, secondary and advanced treatment of

sewage (domestic waste water), Definition and concept of: biodegradation, bio deterioration and

biotransformation. Biodegradation of plastic, pesticides and hydrocarbons Bioremediation,

Bioleaching, Biosorption, Biopesticides, Biofertilizers, Biofuels, Biosensors, Bioindicators,

Biodegradable plastics

Unit II: Xenobiotic and recalcitrant compounds Bioaccumulation and biomagnification. Assessment of water and wastewater quality: Concept of

COD, DO and BOD. Indicators of faecal pollution and MPN and MFtechnique for coliforms.

Significance and principal of IMViC.

UNIT III: Industrial Biotechnology

Basic Principles of Industrial Biotechnology: Important commercial products produced by

microorganisms and GMOs and their applications. Microbes in industry – foods from

microorganism (vinegar and cheese). production of citric acid, amylases, proteases, vitamin B12,

beer, wine, biogas, methane, hydrogen.

Unit IV: Food Biotechnology

Production and types of cheese, microorganisms as food –production of mushroom and spirulina,

assessment of microbiological quality of various foods. Industrial awareness: Quality control and

quality assurance in food and pharamaceutical industry, concept of current good manufacturing

practices in pharmaceutical industry

Unit V: Agricultural Biotechnology

crop improvement, herbicide resistance, insect resistance, virus resistance, plants as bioreactors.

Genetic modification in Agriculture –transgenic plants, genetically modified foods, application,

future applications, ecological impact of transgenic plants

Page 49: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

COURSE: GE – FUNDAMENTALS OF DEVELOPMENTAL BIOLOGY (FOR EVEN

SEMESTER)

PURPOSE-

This course presents the genetic, cellular and molecular mechanisms involved in the

development of animal embryology

Unit I: Gametogenesis and Fertilization

Definition, scope & historical perspective of development Biology, Gametogenesis –

Spermatogenesis, Oogenesis Fertilization - Definition, mechanism, types of fertilization. Different

types of eggs on the basis of yolk.

Unit II: Early embryonic development

Cleavage: Definition, types, patterns & mechanism Blastulation: Process, types & mechanism

Gastrulation: Morphogenetic movements– epiboly, emboly, extension, invagination, convergence,

de-lamination. Formation & differentiation of primary germ layers, Fate Maps in early embryos.

Unit III: Embryonic Differentiation

Differentiation: Cell commitment and determination- the epigenetic landscape: a model of

determination and differentiation, control of differentiation at the level of genome, transcription

and post-translation level Concept of embryonic induction: Primary, secondary & tertiary

embryonic induction, Neural induction and induction of vertebrate lens.

Unit IV: Organogenesis

Neurulation, notogenesis, development of vertebrate eye. Fate of different primary germlayers

Development of behaviour: constancy & plasticity, Extra embryonic membranes, placenta in

Mammals

.

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DEPARTMENT: MASS COMUNICATION AND JOURNALISM

COURSE: GE – BASICS OF JOURNALISM (FOR ODD SEMESTER)

Pre requisites: Basic Knowledge of 12th grade communicative English.

Course Objective:

1.Gain an overview of news journalism’s public service role in a democratic society

2.Become familiar with fundamental principles of journalism, such as truth-telling, watchdog

reporting,

accuracy, courage, tolerance, justice, minimizing harm

3.Learn basics of journalism law, history and ethics

Course Outcome:

Demonstrate critical thinking skills necessary to collect, evaluate, organize and disseminate news

1.Analyze relative newsworthiness of various fact sets, using elements of newsworthiness

(proximity, interest, importance, impact, timeliness)

2.Write a simple news using set of facts

3.Distinguish news from infotainment, public relations, advertising and non-journalistic

blogging, as well as the difference between news and opinion

Unit 1: Understanding News Ingredients of news meaning, definition, nature The news process:

from the event to the reader (how news is carried from event to reader) Hard news vs. Soft news,

basic components of a news story Attribution, embargo, verification, balance and fairness,

brevity, dateline, credit line, byline.

Unit 2: Tabloid press Language of news- Robert Gunning: Principles of clear writing, Rudolf

Flesch formula- skills to write news.

Unit 3: Understanding the structure and construction of news Organizing a news story, 5W‘s and

1H, Inverted pyramid Criteria for news worthiness, principles of news selection, importance of

research in news, sources of news, use of internet

Unit 4: Different mediums-a comparison Language and principles of writing: Basic differences

between the print, electronic and online journalism Citizen journalism

Unit 5: Role of Media in a Democracy Responsibility to Society press and Democracy

Contemporary debates and issues relating to media Ethics in journalism, debates discussion and

practical writing /Viva.

Books/References

1. Bruce D. Itule and Douglas A. Anderson. News writing and reporting for today’s

media; McGraw Hill Publication, 2000. –

2. M.L. Stein, Susan Paterno& R. Christopher Burnett. News writer’s Handbook: An

Introduction to Journalism; Blackwell Publishing,2006.

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3. George Rodmann. Mass Media in a Changing World; Mcgraw Hill Publication,2007.

4. Carole Flemming and Emma Hemmingway. An Introduction to Journalism; Vistaar

Publications,2006. Richard Keeble. The Newspaper’s Handbook; Routledge

Publication,2006.

5. JohnHohenberg: Professional Journalists; Thomson Learning.

6. M.V. Kamath: Professional Journalism; Vikas Publishing, New Delhi.

COURSE: GE – SCIENTIFIC REPORT WRITING AND EDITING (FOR EVEN

SEMESTER)

Course Overview

Science and technology profoundly shape our lives, changing the way we communicate with

others, the kinds of careers we will have, and the quality of our natural environment. When science

and technology move from laboratory to corporate boardroom to Media houses writing is involved

in every step in this process. This course will focus on the writing that constitute science and

technology. We will explore the writing done by scientists, technologists, will examine how

writing circulates through society journalism, press releases, policy makers, citizens.

Course Outcome

• Use writing for the purposes of reflection, action, and participation in academic inquiry

• Work within a repertoire of genres and modes—including digital media—to meet appropriate

rhetorical purposes

• Exercise a flexible repertoire of invention, arrangement, and revision strategies

• Engage in reading for the purposes of reflection, critical analysis, decision-making, and inquiry

• Demonstrate the ability to locate, critically evaluate, and employ a variety of sources for a range

of purposes

• Synthesize external data and documentary sources into your own writing with greater awareness

of proper citation

Unit 1: (4 Lectures)

Introduction to Science Writer Profile; Stories about Scientists; Introduction to New Discovery

Story; Science communication models - problems, its solutions; writing science as news; engaging

writing style; Article analysis – structure, style, voice, narrative.

Unit 2: (8 Lectures)

Writing from science journals; Language goals in scientific writing; reporting on new research;

explanatory writing; Avoiding jargon; New discovery story analysis, Introduction to Feature

Article, Explanatory features; Ethics in writing.

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Unit 3: (6 Lectures)

Select a recent healthcare research study and find both the original study published in a biomedical

journal and another (non-academic) article written about the study findings; Target Audience-Who

is the audience? Purpose of the article; Bibliographic Database Searching and Citation

Management Software; Fact-checking

Unit 4: (8 Lectures)

Interviewing a scientist; Questionnaire Design; Prepare Press releases; Workshopping ideas;

Presentations and Posters; Presentation Slides; Presenting Research; Grant Proposals; Writing

Abstracts; Writing Thesis and Capstone Documents; Survey: Schedule, Sample; Tools of Data

Collection

Unit 5: (6 Lectures)

Planning for print-size, anatomy, grid, design; Format, typography, copy, pictures, advertisements;

Plotting text: headlines, editing pictures, captions; Page-making; Technology and Print; layout,

use of graphics and photographs; Printing Processes: Traditional vs modern; Desk Top Publishing:

Quark Express, Coral Draw, Photoshop

Unit 6: (6 Lectures)

Online Story Package – Use of text, photos, video, audio, graphics; working together to tell a story;

Types of Multimedia Content; Supporting Text; Story Pitch; Search Operators; Database;

Hyperlink; Rule of Thirds; Rendering; Authenticity; In-Depth Story

REQUIRED TEXTBOOK(S):

1. Alley, Michael. The Craft of Scientific Writing, third edition. New York: Springer, 2009.

ISBN: 0387947663 ISBN-13: 9780387947662

2. Alley, Michael. The Craft of Scientific Presentations, second edition. New York: Springer,

2013. ISBN: 1441982787 ISBN-13: 9781441982780

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DEPARTMENT: HOSPITALITY AND TOURISM ADMINISTRATION

COURSE: GE – HOSPITALITY & TOURISM ENTREPRENEURSHIP (FOR ODD

SEMESTER)

UNIT 1: 08 LECTURES

Introduction to Entrepreneurship Development: Definition of entrepreneurship-emergence of

entrepreneurial classes-theories of entrepreneurship-role of socio-economic environment-

characteristics of entrepreneur-leadership, risk taking, decision-making & business planning.

Scope in tourism. Introduction to entrepreneur and entrepreneurship.

UNIT 2: 08 LECTURES

Opportunity analysis: External environmental analysis (economic, social & technological)-

competitive factors-legal requirements for establishment of a new unit related to tourism & raising

of funds-venture capital sources & documentation required.

UNIT 3: 08 LECTURES

Entrepreneurial Behaviour: Innovation and entrepreneur, entrepreneurial behaviour &

psychological theories.

UNIT 4: 08 LECTURES

Entrepreneurial Development Program (EDP): EDPs & their role, relevance and

achievements-role of Government in organizing EDPs-evolution of EDPs. Social responsibility in

business.

UNIT 5: 10 LECTURES

Role of Entrepreneur: Role of an entrepreneur in economic growth as an innovator, generation

of employment opportunities, complementing economic growth, bringing about social stability &

balanced regional development of industries with emphasis on tourism, foreign earnings etc.

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COURSE: GE – PERSONALITY DEVELOPMENT (FOR EVEN SEMESTER)

Unit I- 4 lectures

Introduction to bio data, features of a bio data, types of bio data, importance of bio data,

specifications, preparation of bio data.

Unit II- 4 lectures

Group discussion: importance, participation, rules to be followed, listening skills, do’s and don’ts

Personal interview: Self introduction, expressing yourself, understanding the interviewers’ need,

do’s and don’ts

Unit III- 4 lectures

Grooming and hygiene: basic grooming ideas, self-check of grooming, healthy practices.

Unit IV- 6 lectures

Speech on a given topic (extempore speech); presentation Skills; public speaking.

Time Management; Organizational Skills; Stress management; Team Building Skills; Change

management.

Unit V- 4 lectures

Table manners, telephone etiquettes, body language

Page 55: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

DEPARTMENT: MICROBIOLOGY

COURSE: GE – MOLECULAR SECRETS OF LIFE (FOR ODD SEMESTER)

Unit 1: Origin of Life:

Formation of life, Concept of Biogenesis and abiogenesis, Miller-Urey experiment, properties of

water, contribution of scientists to the journey of biology, Discovery of microscope and its types.

Theories of evolution, Contribution of Lamarck and Darwin.

Unit 2: Cell structure and function:

Prokaryotic and eukaryotic cell structure. Difference between prokaryotic and eukaryotic cell,

Plant and animal cell, Cell envelop, Cell organelles and their functions. Eukaryotic cycle definition

and its regulation, phases of cell cycle, Cell division and its significance, types of cell division,

Mitosis and meiosis, different stages of cell division.

Unit 3: Biodiversity and classification:

Classification living organisms, nomenclature system, Characteristics of different classes of

organisms, Three domains of life,

Unit 4: Macromolecules of life:

Carbohydrates and sugars, amino acids and proteins, enzymes, Lipids, Nucleic acid (both DNA

and RNA)

Unit 5: Information flow in life:

Concept of gene and chromosome, Replication, Transcription, Translation, Methods of gene

transfer in prokaryotes like Transformation, Transduction and Conjugation, Operon concept,

Mutation.

Unit 6: Metabolic pathways in life:

Carbohydrate metabolism – glycolysis, TCA cycle, oxidative phosphorylation. Amino acid

metabolism and urea cycle, Fatty acid metabolism – β oxidation of saturated and unsaturated

fatty acids, photosynthesis.

Page 56: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

COURSE: GE – INTRODUCTION TO FORENSIC SCIENCE (FOR EVEN SEMESTER)

Unit 1: History of Development of Forensic Science in India:

Functions of forensic science. Historical aspects of forensic science. Definitions and concepts in

forensic science. Scope of forensic science. Need of forensic science. Basic principles of forensic

science. Frye case and Daubert standard.

Unit 2: Tools and Techniques in Forensic Science:

Branches of forensic science. Forensic science in international perspectives, including set up of

INTERPOL and FBI. Duties of forensic scientists. Data depiction. Report writing.

Unit 3: Organizational set up of Forensic Science Laboratories in India

Hierarchical set up of Central Forensic Science Laboratories, State Forensic Science Laboratories,

Government Examiners of Questioned Documents, Fingerprint Bureaus, National Crime Records

Bureau, Police & Detective Training Schools, Bureau of Police Research & Development,

Directorate of Forensic Science and Mobile Crime Laboratories. Police Academies. Police dogs.

Services of crime laboratories. Basic services and optional services.

Unit 4: Instrumentation:

Sample preparation for chromatographic and spectroscopic evidence. Chromatographic methods.

Fundamental principles and forensic applications of thin layer chromatography, gas

chromatography and liquid chromatography. Spectroscopic methods. Fundamental principles and

forensic applications of Ultravioletvisible spectroscopy, infrared spectroscopy, atomic absorption

spectroscopy, atomic emission spectroscopy and mass spectroscopy. X-ray spectrometry.

Colorimetric analysis and Lambert-Beer law. Electrophoresis – fundamental principles and

forensic applications. Neutron activation analysis – fundamental principles and forensic

applications.

Unit 5: Basics of Criminology:

Definition, aims and scope. Theories of criminal behavior – classical, positivist, sociological.

Criminal anthropology. Criminal profiling. Understanding modus operandi. Investigative strategy.

Role of media.

Unit 6: Basics of Fingerprinting:

Introduction and history, with special reference to India. Biological basis of fingerprints.

Formation of ridges. Fundamental principles of fingerprinting. Types of fingerprints. Fingerprint

patterns. Fingerprint characters/minutiae. Plain and rolled fingerprints. Classification and

cataloguing of fingerprint record. Automated Fingerprint Identification System. Significance of

poroscopy and edgeoscopy.

Unit 7: Biological Evidence:

Nature and importance of biological evidence. Significance of hair evidence. Transfer, persistence

and recovery of hair evidence. Structure of human hair. Comparison of hair samples. Morphology

and biochemistry of human hair. Comparison of human and animal hair. Types and identification

of microbial organisms of forensic significance. Identification of wood, leaves, pollens and juices

as botanical evidence. Diatoms and their forensic significance.

Page 57: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

DEPARTMENT: ECONOMICS

COURSE: GE – ECONOMIC HISTORY OF INDIA (FOR ODD SEMESTER)

Course Description

Using appropriate analytical frameworks, this course reviews major trends in economic indicators

and policy debates in India in the post-Independence period, with particular emphasis on paradigm

shifts and turning points. Given the rapid changes taking place in India, the reading list will have

to be updated annually.

Course Outline

Unit 1: Economic Development since Independence

Major features of the economy at independence; growth and development under different policy

regimes-goals, constraints, institutions and policy framework; an assessment of performance-

sustainability and regional contrasts; structural change, savings and investment.

Unit 2: Population and Human Development

Demographic trends and issues; education; health and malnutrition.

Unit 3; Growth and Distribution

Trends and policies in poverty; inequality and unemployment

Unit 4: Policies and Performance in Agriculture

Growth; productivity; agrarian structure and technology; capital formation; trade; pricing and

procurement.

Unit 4: Policies and Performance in Industry

Growth; productivity; diversification; small scale industries; public sector; competition policy;

foreign investment.

Unit 6: Trends and Performance in Services

Readings:

1. Kaushik Basu, 2009, ―China and India: Idiosyncratic Paths to High Growth, Economic

and Political Weekly, September.

2. Himanshu. 2011, ―Employment Trends in India: A Re-examination, Economic

and Political Weekly, September.

3. Rama Baru et al, 2010, ―Inequities in Access to Health Services in India: Caste,

Class and Region, Economic and Political Weekly, September.

4. Geeta G. Kingdon, 2007, ―The Progress of School Education in India, Oxford

Review of Economic Policy

Page 58: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

COURSE: GE – ECONOMIC DEVELOPMENT (FOR EVEN SEMESTER)

Unit 1: Meanings and nature of development – economic growth, redistribution from growth and

capabilities approach to development, Objectives of development, Measures of development –

Purchasing power parity and Per capita income as an index of development, difference between

growth and development, human development index, developing economy – features, Introduction

to concept of sustainable development,

Unit 2: Factors in economic development - Land: Ownership and tenancy system – fixed rent

contract and share cropping, role of agriculture in development, barriers to agricultural

development and land reforms, Labour – Population and Labor force growth, casual and long term

labor, permanent labor market, Capital: Role of capital accumulation in economic development.

Significance of capital-output ratio, role of technology and technological progress, learning,

human capital, Natural Capital & concept of investment.

Unit 3: Population and Development - Concepts of Population: definitions of fertility, mortality,

birthrates, death rates, fertility rate, life expectancy, infant mortality rate, youth dependency ratio.

Theory of demographic transition

Unit 4: Development strategies - Complementarity and Coordination, Poverty Trap of Nurkse and

Big Push theory of Rosenstein-Rodan , Linkages – backward and forward; linkages, policy and

big push,,

Choice of technology and choice of scale (large vs small) and criteria for investment, Gains from

trade, sustainable development strategies.

Unit 5: Development in a Labour surplus economy - The concept of economic dualism, Disguised

Unemployment, The Informal Sector, Rural-urban migration of labour – Harris-Todaro model,

development in natural resource rich contest

Unit 6: Development, Inequality and poverty - Meaning of inequality, inequality measures, Lorenz

Curve, Range, Coefficient of variation, Gini-coefficient, Kuznet’s Inverted U hypothesis. Poverty,

relative and absolute deprivation with respect to income, Poverty line, Poverty measures – Head

count ratio, Poverty gap ratio, Income gap ratio, Human Poverty Index. Social dimensions of

poverty – rural poverty, women and ethnic minorities and indigenous populations

References:

Development Economics Debraj Ray

Development Economics Hayami

Page 59: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

DEPARTMENT: CHEMISTRY

COURSE: GE – FUNDAMENTALS OF CHEMISTRY (FOR ODD SEMESTER)

Unit 1: Basic concepts of Organic Chemistry

Fundamentals and Applications:

Basic Organic Chemistry Concepts: introduction to organic molecules and functional groups understanding

organic reactions, atomic orbitals, hybridization, orbital representation of methane, ethane, ethyne and

benzene.

Polarity of bonds: Inductive, resonance and steric effects hyper conjugation, and their influence on acidity

and basicity of organic compounds.

Green Chemistry introduction and principles.

Unit 2: Basic concepts of Physical Chemistry

Zeroth Law of Thermodynamics: Equilibrium, State Functions, Temperature, Equations of State.

First Law of Thermodynamics: Work, Heat, Internal Energy, Heat Capacity, Concept of Enthalpy.

Open thermodynamics.

Solutions: Molarity, Normality, Partial Molar Quantities, Ideal Solutions, Non Ideal Solutions, Electrolytes,

Ionic activity and the Debye Huckel Theory, Colligative properties.

Reaction Kinetics: Reaction Rates, Rate Laws, Application.

Unit 3: Basic concepts of Inorganic Chemistry

Atomic Structure & Study of matter:

Study of matter – its properties and behavior; Atomic Structure: Discovery of Electron by J J Thomson, Bohr’s

Theory, De Broglie Hypothesis, Heisenberg’s Uncertainty Principle.

Page 60: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

COURSE: GE – STEREOCHEMISTRY AND CONFORMATION (FOR EVEN

SEMESTER)

Unit 1: Stereochemistry

Introduction, Chirality, Concepts of Isomerism, Types of Isomerism: Structural and Stereoisomerism.

(R) and (S) Nomenclature of asymmetric carbon atoms.

Optical Isomerism or Enantiomerism, Optical Activity.

Biological discrimination of enantiomers.

Racemic mixtures, Enantiomeric excess, Optical purity.

Fischer Projections and their use.

Diastereomers, stereochemistry of molecules with two or more asymmetric carbons.

Geometrical isomerism: cis–trans and, syn-anti isomerism and E/Z notations.

Unit 2 - Conformation

Cycloalkanes and Conformational Isomerism,

Conformational analysis of ethane and n-butane,

Conformation analysis of alkanes: Relative stability, Axial and Equatorial bonds.

Energy diagrams of cyclohexane: Chair, Boat and Twist boat forms; Relative stability with energy

diagrams.

Page 61: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

DEPARTMENT: PHYSICS

COURSE: GE – WHERE DO YOU LIVE? A JOURNEY THOUGH OUR GORGEOUS

UNIVERSE (FOR ODD SEMESTER)

Unit 1: Radiation from stars: spectral lines and their formation; stellar atmosphere.

Unit 2: Telescopes and other detectors.

Unit 3: Special relativity - Basic ideas.

Unit 4: Stellar parameters; Binary stars.

Unit 5: Main sequence stars and their structure; Nuclear processes in stars; End points of stellar

evolution; White dwarfs, Neutron stars and Black holes.

Unit 6: Interstellar medium and star formation.

Unit 7: Cluster of stars.

Unit 8: Galaxies.

Unit 9: Universe on large scale: an overview.

Unit 10: Cosmological moles for a homogeneous and isotropic universe.

Unit 11: Early Universe.

References:

1. The Physical Universe: an introduction to Astronomy - Frank H. Shu

2. Cosmos - Carl Sagan

3. Fundamental Astronomy - H. Karttunen et. al

Page 62: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

COURSE: GE – HISTORY AND PHILOSOPHY OF SCIENCE (FOR EVEN

SEMESTER)

Unit 1: What is Science?

Unit 2: Scientific Reasoning.

Unit 3: Explanation in Science.

Unit 4: Realism and Anti-realism.

Unit 5: Scientific change and Scientific evolution.

Unit 6: Philosophical problems in physics, biology and psychology.

Unit 7: Science and its critics.

Unit 8: Conclusions.

References:

1. Science order and creativity -D. Bohm and D. Peat

2. Understanding Philosophy of Science - J. Ladyman

3. Philosophy of Science: A Contemporary introduction - A. Rosenberg

Page 63: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

DEPPARTMENT: MANAGEMENT

COURSE: GE - ORGANIZATIONAL BEHAVIOR (FOR ODD SEMESTER)

1) Organization- the concept.

2) Human behavior- concepts and practice.

3) Leadership and leadership styles.

4) Motivation- theory and practice.

5) Communication.

6) Individual and Group dynamics.

7) OB and decision making.

8) Presentation and case studies.

COURSE: GE - BUSINESS STRATEGY (FOR EVEN SEMESTER)

1) Concept of business strategy- reactive, preactive and proactive strategies.

2) McKinsey 7S framework.

3) Impact of environment in strategy formulation.

4) Mega, Micro and relevant environment.

5) The strategic management pyramid.

6) Swot analysis.

7) BCG growth share matrix.

Page 64: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

SKILL ENHANCEMENT

COURSE (SEC)

Page 65: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: SEC1 – Mentored Seminar I

Credit: 1 (1L-0T-0P)

In this course, every student has to prepare presentations during the first semester under the

guidance of any faculty of the department who will mentor the student’s work. The students are

taught how to prepare a presentation, how to deliver seminar and to make them comfortable in

answering the questions asked to them during the interactive session. At the end of the semester,

the student has to deliver a lecture on a specific topic.

Page 66: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: SEC2 – Mentored Seminar II

Credit: 1 (1L-0T-0P)

In this course, every student has to prepare presentations during the second semester under the

guidance of any faculty of the department who will mentor the student’s work. The students are

taught how to prepare a presentation, how to deliver seminar and to make them comfortable in

answering the questions asked to them during the interactive session. At the end of the semester,

the student has to deliver a lecture on a specific topic

Page 67: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: SEC3 – Mentored Seminar III

Credit: 1 (1L-0T-0P)

In this course, every student has to prepare presentations during the third semester under the

guidance of any faculty of the department who will mentor the student’s work. The students are

taught how to prepare a presentation, how to deliver seminar and to make them comfortable in

answering the questions asked to them during the interactive session. At the end of the semester,

the student has to deliver a lecture on a specific topic

Page 68: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: SEC4 – Mentored Seminar IV

Credit: 1 (1L-0T-0P)

In this course, every student has to prepare presentations during the fourth semester under the

guidance of any faculty of the department who will mentor the student’s work. The students are

taught how to prepare a presentation, how to deliver seminar and to make them comfortable in

answering the questions asked to them during the interactive session. At the end of the semester,

the student has to deliver a lecture on a specific topic

Page 69: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

ABILITY ENHANCEMENT

COMPULSORY COURSES

(AECC)

Page 70: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: AECC1 – Communicative English

Credit: 2 (2L-0T-0P)

Component: Theory

Unit 1 - Functional grammar Tenses: basic forms and use; sentence formation; common errors; parts of speech, direct and

reported speech structures and voices

Unit 2 - Letter Writing Job application; business letter; editorial letter; email

Unit 3 - Essay Writing Overall argument; consistent logic; main points; paragraphs; introduction & conclusion

Unit 4 - Report Writing Manuscript; memo

Unit 5 - Precis Writing Understanding main points; inculcating precision; reducing to basics

Unit 6 - Note Making

Unit 7 - Other Kinds of Texts Notice; Circular; Agenda; Minutes

Unit 8 - Presentation Skills Soft skills; relevance of content; knowledge and confidence

Unit 9 - Group Discussion The basic structure of GD's; workshops to develop participation and team-work skills

Unit 10 - Role play What is 'role play'? identifying and understanding one's role; workshops

Unit 11 - Developing Interview Skills The "Do's & Don'ts" of Interviews; verbal proficiency; personality development; mock-interviews

References:

Nilanjana Gupta - Communicate with Confidence (Anthem Press, 2011)

Barun Mitra - Effective Technical Communication: Guide for Scientists and Engineers (OUP,

2006)

Page 71: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: AECC1 – Environmental Science

Credit: 2 (2L-0T-0P)

Component: Theory

Unit 1: Environment and its components:

Definition, Geographical distribution of environment, Environmental chemistry, Atmosphere and

its composition.

Unit 2: Forest resources:

Use and over exploitation, deforestation, timber extraction, mining, dams and their effects on

forests, tribal people.

Unit 3: Water resources:

Use and over-utilization of surface and ground water, floods, drought, conflicts over water,

dams- benefits and problems.

Unit 4: Food resources:

World food problems, changes caused by agriculture and over-grazing, effects of modern

agriculture, fertilizer and pesticides, water logging, salinity.

Unit 5: Energy resources:

Growing energy needs, renewable and non-renewable energy resources, use of alternative energy

sources.

Unit 6: Land resources:

Land as a resource, land degradation, man induced landslides, soil erosion and desertification.

Unit 7: Ecosystem, Biodiversity and its Conservation:

Concept of ecosystem, structure and function of ecosystem, Energy flow, Bio-geological cycles,

Introduction to biodiversity, genetic diversity, species diversity, ecological diversity,

Biogeographical classification of India, Biodiversity Hot-spots, conservation of biodiversity.

Unit 8: Environmental Pollution:

Definition, cause and effect of pollution, Control measures of pollution, Air pollution, Water

pollution, Soil pollution, Noise pollution, Solid waste management, Disaster management, role of

the society to control pollution.

Unit 9: Environmental issues, Laws and ethics:

Water conservation, climate change: cause and effect, global warming, acid rain, ozone layer

depletion, hazardous material industries, Wasteland reclamation, Environment protection act, Air

(prevention and control of pollution) act, Water (prevention and control of pollution) act, Wildlife

protection act, Forest conservation act, issues involved in enforcement of environment legislation,

Public awareness.

Page 72: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

UNIVERSITY SPECIFIED

COURSE (USC)

Page 73: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: USC1 – Foreign Language –I (German)

Credit: 2 (2L-0T-0P)

Component: Theory

Lesson 1

Speech acts:

Greetings and farewells

1st, 2nd and 3rd person introduction.

Speaking about other persons

Numbers till 20

Exchanging telephone numbers and E-mail addresses.

How to spell a word?

Speaking about countries and languages.

Grammar: W-Questions and declarative sentences, personal pronouns- I.

Vocabulary: Numbers, countries and languages.

Lesson 2:

Speech acts:

Speaking about hobbies.

Weekdays and weekends.

Speaking about work, profession and working hours.

Numbers above 20

Seasons

Making profiles on the internet

Grammar: Definitive articles, verbs and personal pronouns-II, yes/no questions, plurals, verbs

'haben’ and ‘sein’.

Vocabulary: Hobbies, Days of the week, numbers from 20, months of the year, seasons

Lesson 3

Speech acts:

To name places and buildings

To ask questions about places

Picture stories

To enquire about things

Transportation

Concept of international words

Grammar: Articles for nouns, definite articles, indefinite articles, negative articles, imperative

sentences.

Vocabulary: Places and buildings, transportation, directions.

Page 74: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: USC1 – Foreign Language –I (Spanish)

Credit: 2 (2L-0T-0P)

Component: Theory

1. Introduction, Alphabets

2. Vocabulary (Relatives, Fruits, Flowers, Colours, Food, Dress, Days of Week, Month,

year etc.)

3. Numbers

4. Noun

5. Subject Pronoun

6. Indicative Mood

7. Verbs: - Regular

8. Verbs Irregular: - Ser, Estar, Tener, Haber, poder, poner etc.

9. Verbs Irregular: - Stem Changing (e to ie), (e to i), (o to ue)

10. Adjective: -Regular Comparative and Superlative

11. Reflexive Verb

12. Object Pronoun

13. Preposition

14. Demonstrative Adjective

15. Possesive Adjective

16. Possesive Pronoun

17. Por and Para

18. Past Tense: - Preterite

19. Audio

20. Conversation

Page 75: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: USC1 – Foreign Language I (Japanese)

Credit: 2 (2L-0T-0P)

Component: Theory:

a. Course Title: Japanese Language Course

b. Learning Objectives:

Can understand and use familiar everyday expressions and very basic phrases aimed at the

satisfaction of needs of a concrete type.

Can introduce him/herself and others and can ask and answer questions about personal details

such as where he/she lives, people he/she knows and things he/she has.

Can interact in a simple way provided the other person talks slowly and clearly and is

prepared to help.

Text Books:

① Marugoto: Japanese language and culture Starter A1 Coursebook for communicative

language competences (Goyal Publisher & Distributer Pvt Ltd. New Delhi)

② Marugoto: Japanese language and culture Starter A1 Coursebook for communicative

language activities (Goyal Publisher & Distributer Pvt Ltd. New Delhi)

1. Japanese Script & Greetings

Hiragana (Japanese Native Script)

Katakana (Foreign Script)

Kanji

Exchange greetings in Japanese

2. Japanese Vocabulary

Country Names, Languages, Occupations, Family, People, Numbers

Food, Drinks, Food for Lunch, Easting Places

Home, Furniture, Places to visit Near buy, Rooms, Things in the room

Daily routines, Time, Free-time activities, Places, Calendar

3. Basic Conversation & Grammar

4. Listening, Reading and Writing activities in Japanese

Self-introduction

My Family

Favorite Food

My family's breakfast

My breakfast, My lunch

My home, My room

My daily life

My week's schedule

Page 76: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: USC2 – Foreign Language II (German)

Credit: 2 (2L-0T-0P)

Component: Theory

Lesson 4:

Speech acts: Talk about food, planning a shopping, conversations during shipping, conversations

in a Restaurant, understanding texts with W-Questions.

Grammar: Positions in a sentence, sentence structure, ‘Akkusativ’ and 'Akkusativ'-verbs.

Vocabulary: meals, groceries, beverages, shops and businesses.

Lesson 5:

Speech acts: Understanding of time and to call, informations with date and time, talking about

family, planning an appointment, to apologise for delay, cancellation of an appointment over the

telephone.

Grammar: Informations with date and time with prepositions 'um’, 'am’, 'von’……. ‘bis’,

possessive articles, Modal verbs,

Vocabulary: Daily routine, time, family.

Lesson 6:

Speech acts: Planning something together, to speak about birthdays, to receive and send

invitations, talk about events, finding of particular informations in a text.

Grammar: separable verbs, preposition 'für’ for ‘Akkusativ’, personal pronouns, past tense of

'haben’ and 'sein’.

Vocabularies: Hobbies, food, beverages, passion and events

Page 77: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: USC2 – Foreign Language II (Spanish)

Credit: 2 (2L-0T-0P)

Component: Theory

1. Gustar , Encantar, Doler Verb

2. Some More irregular Verbs- Saber , Conocer , querer, hacer etc

3. Past Tense:- Preterite indefinido

4. Audio

5. Conversation

6. Comprehension

7. Picture description

8. Letter Writing

9. Paragraph Writing

10. Form Filling

Page 78: SISTER NIVEDITA UNIVERSITY SYLLABUS FOR THREE YEARS …B.Sc. Microbiology (H) Course Structure Category Course name Code Credit Teaching Scheme L T P Semester – I CC – 1 Fundamentals

Course: USC2 – Foreign Language II (Japanese)

Credit: 2 (2L-0T-0P)

Component: Theory

a. Course Title: Japanese Language Course

b. Learning Objectives:

Can understand and use familiar everyday expressions and very basic phrases aimed at the

satisfaction of needs of a concrete type.

Can introduce him/herself and others and can ask and answer questions about personal details

such as where he/she lives, people he/she knows and things he/she has.

Can interact in a simple way provided the other person talks slowly and clearly and is

prepared to help.

d. Text Books:

① Marugoto: Japanese language and culture Starter A1 Coursebook for communicative

language competences (Goyal Publisher & Distributer Pvt Ltd. New Delhi)

② Marugoto: Japanese language and culture Starter A1 Coursebook for communicative

language activities (Goyal Publisher & Distributer Pvt Ltd. New Delhi)

1. Japanese Script

Kanji

2. Japanese Vocabulary

Hobbies (sports, films, music, etc.), Places, Events, Calendar

Transport, Places in Town, Locations

Souvenirs, Counting Numbers, Clothes, Prices

Holiday activities

3. Conversation & Grammar

4. Listening, Reading and Writing activities in Japanese

My hobby

My town

My shopping last week

Clothes that I like

My Holiday trip

Experiences in Japan