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Next Generation Sequencing Congress
Day 1 Steam 1:
Part 1: NGS And Future Directions
• Delivering Genomic-based Precision based Medicine
• Multi Omics Data Integration and Whole Genome
Sequencing Data Analysis
Part 2: Long Read Sequencing For Human Genomes And
De Novo Studies
Technological updates
• Identification of structural variants and improvements
in the characterisation of genetic variation
• Implications on biological mapping
• De novo cluster of long reads by gene from
transcriptomics
• Library Prep for Haplotype Phasing and De Novo
Sequencing
Other applications – whole length transcript and direct RNA
sequencing and alternative splicing
Day 2 Steam 1:
Part 1: Delivering Genomic Based Medicine
Accuracy, cost and coverage of short and long read
sequencing
• Pharmacogenomics and Genomic Based Medicine
• Clinical Cytogenetics: The Need For Nucleotide Resolution
Part 2: Short and Long Read Sequencing in the Clinic
• Applications in the Clinic Applications of Short and Long
Read Sequencing in Oncology, Immuno- oncology,
Cardiology and metabolic Diseases
• Precision Surveillance Of Multidrug-Resistant
Organisms And Infection Control Practice
Single Cell Analysis Congress
Day 1 Stream 2: Spatial Omics
Spatial Transcriptomics , Genomics and Spatial Profiling
• Integrating single-cell RNA-Seq with spatial transcriptomics
• Spatial cell atlases using in situ sequencing
• Barcoded solid-phase RNA capture for Spatial
Transcriptomics profiling
• Single-molecule RNA FISH method
• Digital Spatial Profiling- combining RNA sequencing and
protein profiling
Other Technologies
Imaging technology for detection and addressing challenges of
human samples versus mouse based samples
Day 1 Stream 3:
Part 1- Single Cell ‘Omics Analysis: Current And Emerging
Tools
Single cell multi - omics analysis
• Omics Analysis On Basic Science
• Genomics
• Transcriptomics
• Proteomics
• Epigenomics
Part 2: Single Cell in Clinical Use – Applications &
Diagnostic Development
Single Cell Therapeutic applications:
• neurology and immuno-oncology
• Single cell diagnostic development and clinical
applications
• Studies of Single Cell in Clinical Use - oncology,
• Emerging and Novel Tools: Microfludics, nanotechnology
and Imaging technologies
Single Cell Analysis Congress
Day 2 Stream 1: Single-Cell Analysis In Drug Discovery and
Development
Case studies: Oncology, Immunotherapy, Neurodegenerative,
Autoimmune and Rare diseases using multi-omics approaches
Pharma and academic focus –
• Single cell in discovery and development for target
validation
• Single Cell Analysis in T Cell and Antibody development
• Spatially resolved omics in drug discovery and validation
Day 2 Stream 2: Single Cell Analysis: Overcoming
Challenges
Challenge 1: Sample preparation, Cell Isolation and
Purification for single cell analysis
High Throughput Protein to Protein Interaction and Single Cell
Genomics
Challenge 2: bioinformatics:
• Statistical analysis of single cell data
• Cluster statistical methods for single cell analysis
• Dealing with multiomics data coming from single cell
analysis
Day One Interactive Workshop:
Discussion workshop: Accuracy, cost and coverage of short
and long read sequencing
Day Two Interactive Workshop:
Spatial Transcriptomics
Ideal for those who work in Single Cell Sample Preparation
and Bioinformatics
If you’re on Twitter, make sure to follow us
@NGSUSCongress and join the Congress conversation
on #NGSUS20
For more information please contact [email protected]
Confirmed Speakers 2020
Bruce Aronow
Cincinnati Children's
Hospital Medical Center
Brian Dougherty
Astra Zeneca
Franziska Michor
Dana-Farber Cancer
Institute
Chia-Lin Wei
The Jackson Laboratory
Bogdan Budnik
Harvard University
Esperanza Anguiano
BMS
Computational Biology
Molecular Biology
Molecular Diagnostics
Bioinformatics
Clinical Diagnostics Development
Long Read
Short Read
Single Cell Genomics
Single Cell Biology
Biochemistry
Single Cell Transcriptomics
Single Cell Proteomics
Drug Discovery
Translational Biomarkers
Diagnostics
NGS Platforms
Genome Sequencing
NGS Bioinformatics
Data Integration
Sample Preparation
Diagnostics Development
Single Cell RNA/DNA Sequencing
Microfluidic Solutions
Molecular Profiling
Protein Profiing
Single Cell Transcriptomics
Single Cell Proteomics
Meet Senior Decision Makers
350 delegates from leading research & academic institutions, clinical
research institutions as well as major pharmaceutical and biotech companies
will attend the event. Delegate job functions include:
Discover New Solutions
Formal and informal meeting opportunities offer delegates the chance to discuss
key solutions with leading service providers. Services to be discussed include:
Benefits to Attending
Hear from and meet with the key innovators in next generation sequencing, and single cell analysis. 2020 speakers include: Senior Director, Alnylam
Pharmaceuticals; Director, University of Illinois; Director, Massachusetts General Hospital
✓ Discuss the future of NGS and long lead sequencing, and benefit from critical discussions and thought-provoking presentations on Long read
sequencing For Human Genomes And De Novo Studies, Data analysis in denovo assembly and structural variants, Bioinformatics and mapping tools
✓ Deliver Genomic Based Medicine- Applications of long and short read sequencing in the Clinic
✓ Multi-Omic Single Cell Analysis - discuss and debate the critical challenges and opportunities in Genomic, Transcriptomics and Proteomics
✓ Benefit from updates and highlights in Spatial Transcriptomics, Genomics and Digital Spatial Profiling as well as implications on sample and data analysis.
✓ Discover the latest advancements in single cell analysis in drug discovery and development. The comprehensive agenda covers important areas such
as key therapeutic applications in oncology, neurology and immuno-oncology, and the latest diagnostics development
✓ Overcoming Challenges in library preparation, bioinformatics and multi-omic data integration
✓ Unparalleled networking opportunities. The two-day congress offers unrivalled networking opportunities, creating an interactive platform for high-level
scientific and business discussions. Participate in formal or informal discussions during our networking breaks and pre-organised 1-2-1 meetings
For more information please contact [email protected]
Confirmed and Reserved Speakers Include:
2020 Next Generation Sequencing USA Congress
• Cynthia Morton, Director of Cytogenetics, Harvard University
• Jane Wilkinson, Senior Director, Broad Genomics Alliance Management, Broad Institute at Harvard & Massachusetts Institute of Technology
• Chia-Lin Wei, Director of Genome Technology, The Jackson Laboratory
• Hank Wang, Professor of Clinical Pathology & Director of Microbiology, Virology & Molecular Diagnostics Laboratories, Westchester Medical Center
& New York Medical College
• Suzanne Leal, Sergievsky Family Professor of Neurological Sciences, Director - Center for Statistical Genetic - Columbia University
• Isidore Rigoutsos, Richard W. Hevner Professor of Computational Medicine, Director - Professor - Dept. of Pathology, Anatomy & Cell Biology,
Thomas Jefferson University
• Stuart A. Scott, Associate Professor, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, ,Division Head,
Pharmacogenomics, Director, Cytogenetics and Cytogenomics
• James Willey, Professor of Medicine and Pathology, George Isaac Chair for Cancer Research, University of Toledo
• Michael Heller, Professor, University of California, San Diego
• Rong Mao, Professor of Pathology, University of Utah School of Medicine, Medical Director, Molecular Genetics and Genomics, ARUP Laboratories
• Liudmila Sergeevna Mainzer, Technical Program Manager, Genomics, National Center for Supercomputing Applications, Research Assistant
Professor, Institute of Genomic Biology, University of Illinois
• Zhaohui Steve Qin, Associate Professor, Department of Biostatistics, Emory University
• Kiran Garimella, Senior Computational Scientist, Broad Institute
• Fritz Sedlazeck, Assistant Professor, Human Genome Sequencing Center, Baylor College of Medicine
• Cecilia CS Yeung, Assistant Professor - University of Washington, Dept. of Pathology, Medical Director - Molecular Oncology Laboratory, Fred
Hutchinson Cancer Research Center
For more information please contact [email protected]
Confirmed and Reserved Speakers Include: 2020 Single Cell Analysis Congress
• Brian Dougherty, Executive Director of Translational Medicine, AstraZeneca Oncology R&D
• Bin Li, Director, Computational Biology, Takeda
• Esperanza Anguiano, Associate Director, Clinical Genetics and Genomics, Translational Medicine, Bristol-Myers Squibb Company
• Jin Jen, Director, Sequencing Research, Celgene
• Shanrong Zhao, Director, Pfizer
• WADE DAVIS, Director Computational Genomics, Genomics Research Center (GRC), AbbVie
• Qu Zhang. Senior Scientist, MedImmune
• Kalpit Shah, Former Senior Research Investigator, Bristol-Myers Squibb
• Dann Huh, Senior Scientist, Biogen
• Giovanni Tonon, Director, Center for Translational Genomics and Bioinformatics, Head, Functional Genomics of Cancer Unit, Division of Experimental Oncology, San
Raffaele Scientific Institute
• Gregory Timp, Professor, Notre Dame University
• Suraj P. Bhat, Professor, Vision Molecular Biology Laboratory, Stein Eye Institute, University of California
• Charles Wang, Director, Center for Genomics, Professor, Department of Basic Sciences, Loma Linda University School Of Medicine
• Bruce Aronow, Co-Director, Cincinnati Children's Hospital Medical Center
• Bogdan Budnik, Director of Proteomics, Harvard University
• Rob Mitra, Alvin Goldfarb Distinguished Professor of Computational Biology, Professor of Genetics, MGI
• Vladimir Kiselev, Informatics Team Leader, Wellcome Trust Sanger Institute
• Franziska Michor, Professor of Computational Biology, Department of Data Sciences, Dana-Farber Cancer Institute
• David H. Perlman, Principal Scientist, Proteomics and Target Discovery Lead, Merck Research Labs Cambridge Exploratory Sciences Center
• Xiaowei Zhuang, Howard Hughes Medical Institute Investigator, David B. Arnold Jr. Professor of Science, Professor of Chemistry and Chemical Biology, Professor of
Physics, Harvard University
• Michael Kharas, Lab Head, Kharas Lab, Memorial Sloan Kettering Cancer Center
• Aubrey Thompson, Professor of Cancer Biology, Mayo Clinic, US
• Lihua Julie Zhu, Professor and Head of Bioinformatics Core, University of Massachusetts
• May Dongmei Wang, Professor, Director of Biomedical Big Data Initiative, Georgia Institute of Technology and Emory University
• Yu-Hwa Lo, Professor, Electrical and Computer Engineering, National Nanotechnology Coordinated Infrastructure (NNCI)
• Nikolai Slavov, Professor, Northeastern University
• Joel Voldman, Professor of Electrical Engineering, Associate Head, Electrical Engineering and Computer Science, MIT
• Xianjun Dong, Director of Computational Neuroscience, Brigham and Women's Hospital
• Joshua Campbell, Co-Director of the Single Cell Sequencing Core and Assistant Professor, Boston University
• Guo-Cheng Yuan, Associate Professor, Dana-Farber Cancer Institute
• Abbas Rizvi, Associate Research Scientist, Maniatis Lab, Columbia’s Zuckerman Institute
• Sara Rouhanifard, Assistant Professor, Northeastern University
• Malte Kühnemund, CEO, CARTANA
• Mark Borodovsky, Director, Center for Bioinformatics & Computational Genomics, Georgia Tech and Emory University
For more information please contact [email protected]
2019 Next Generation Sequencing and Clinical Diagnostics & Single Cell Analysis Sponsors Included:
Bronze Sponsors:
Network And Programme Sponsors:
For more information please contact [email protected]
6th Annual Next Generation Sequencing & Single Cell Analysis USA Congress
Day One – 7 April 2020
07.30 – 08.20 Registration
08.20 – 08.25 Oxford Global’s Welcome Address
08.25 – 08.30 Chairperson’s Opening Address
6th Annual Next Generation Congress 6th Annual Single Cell Analysis Congress
08.30 – 09.00 Stream Keynote Address:
Genome Sequencing Data Analysis
CONFIRMED: Suzanne Leal, Sergievsky Family Professor
of Neurological Sciences, Director - Center for Statistical
Genetic - Columbia University
Stream Keynote Address:
A Multi-Center Cross-platform Benchmarking Study on scRNA-seq
• A multi-center cross-platform scRNA-seq study showing a large variation and batch effect existed across scRNA-seq
platforms/technologies and centers
• Batch correction is the critical in scRNA-seq study across different batch of experiments and the nature of biological
samples dictate the selection of best batch correction methods
• A large cross-platform/center scRNA-seq reference data consisting both mixed and non-mixed cells from two distinct
cell lines were generated for future benchmarking evaluation of new single-cell technologies and bioinformatics
algorithms
CONFIRMED: Charles Wang, Director, Center for Genomics, Professor, Department of Basic Sciences, Loma Linda
University School Of Medicine
6th Annual Next Generation Congress 6th Annual Single Cell Analysis Congress
Day 1 Steam 1
Part 1: Multi Omics Data Integration and Whole Genome
Sequencing Data Analysis
Day 1 Stream 2: Spatial Omics Day 1 Stream 3
Part 1: Single Cell Proteomics and Epigenomics
09.00 – 09.30 Stream Keynote Address:
Multi Omic Data Integration
RESERVED: Isidore Rigoutsos, Richard W. Hevner
Professor of Computational Medicine, Director
- Professor - Dept. of Pathology, Anatomy & Cell Biology,
Thomas Jefferson University
Stream Keynote Address:
A Multimodal Strategy for a Single Cell Atlas of the
Human Spinal Cord
RESERVED: Abbas Rizvi, Associate Research Scientist,
Maniatis lab, Columbia’s Zuckerman Institute
Stream Keynote Address: Single Cell Proteomics
CONFIRMED: Bogdan Budnik, Director of Proteomics,
Harvard University
09.30 – 10.00 Solution Provider Presentation
For sponsorship opportunities please contact
Solution Provider Presentation
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Solution Provider Presentation
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10.00 – 11.20 Morning Coffee & Refreshments, Poster Presentation Sessions, One to One Meetings x3
For more information please contact [email protected]
6th Annual Next Generation Sequencing & Single Cell Analysis USA Congress
Day One – 7 April 2020
11.20 – 11.50 Whole Genome Sequencing Data Analysis
CONFIRMED: Jane Wilkinson, Senior Director, Broad
Genomics Alliance Management, Broad Institute at
Harvard & Massachusetts Institute of Technology
Biotagging of Specific Cell Populations in Zebrafish
Reveals Gene Regulatory Logic Encoded in the Nuclear
Transcriptome
CONFIRMED: Scott E. Fraser, Provost Professor of
Biology and Bioengineering, Elizabeth Garrett
Professor of Convergent Biosciences, Director of
Science Initiatives, University of Southern California,
Translational Imaging Center
Single Cell Proteomics by Mass Spectrometry
CONFIRMED: Nikolai Slavov, Assistant Professor,
Northeastern University
11.50-12.20 The Performance Optimization for Next Generation
Sequencing Analysis In Clinical Environment
CONFIRMED: Liudmila Sergeevna Mainzer, Technical
Program Manager, Genomics, National Center for
Supercomputing Applications, Research Assistant
Professor, Institute of Genomic Biology, University of
Illinois
Barcoded Solid-Phase RNA Capture For Spatial
Transcriptomics Profiling
CONFIRMED: Esperanza Anguiano, Associate Director,
Clinical Genetics and Genomics, Translational
Medicine, Bristol-Myers Squibb Company
Single Cell ‘Omics Case Studies And Therapeutic
Applications: Epigenomics
CONFIRMED: Giovanni Tonon, Director, Center for
Translational Genomics and Bioinformatics, Head,
Functional Genomics of Cancer Unit, Division of
Experimental Oncology, San Raffaele Scientific Institute
12.20 – 12.50
Solution Provider Presentation
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Solution Provider Presentation
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12.50 – 13.50 Lunch, Poster Presentation Sessions
PART 2: Future Directions In Long Read Sequencing For
Human Genomes And De Novo Studies
FEATURED STREAM: Spatial Transcriptomics
Part 2: Single Cell in Clinical Use – Applications &
Diagnostic Development
13.50 – 14.20 Long Read Sequencing - Technological Updates
Identification Of Structural Variants And Improvements
In The Characterisation Of Genetic Variation
CONFIRMED: Chia-Lin Wei, Director of Genome
Technology, The Jackson Laboratory
Single-Cell Transcriptome Imaging And Cell Atlas Of
Complex Tissues
CONFIRMED: Xiaowei Zhuang, Howard Hughes Medical
Institute Investigator, David B. Arnold Jr. Professor of
Science, Professor of Chemistry and Chemical Biology,
Professor of Physics, Harvard University
Hidden Heterogeneity And Circadian-Controlled Cell Fate
Inferred From Single Cell Lineages
CONFIRMED: Franziska Michor, Professor of
Computational Biology, Department of Data Sciences,
Dana-Farber Cancer Institute
For more information please contact [email protected]
14.20 – 14.50 Investigating Fusion Genes and Breakpoints in
Cancer Genome
CONFIRMED: Cecilia CS Yeung, Assistant Professor -
University of Washington, Dept. of Pathology, Medical
Director - Molecular Oncology Laboratory, Fred
Hutchinson Cancer Research Center
Spatial Analysis of Single Fiber Cells of the Developing
Ocular Lens Reveals Regulated Heterogeneity of Gene
Expression
CONFIRMED: Suraj P. Bhat, Professor, Vision Molecular
Biology Laboratory, Stein Eye Institute, University of
California
Reproducible Data Analysis Pipeline for Clinical
Translation
CONFIRMED: May Dongmei Wang, Professor, Director of
Biomedical Big Data Initiative, Georgia Institute of
Technology and Emory University
14.50 – 15.20
Solution Provider Presentation
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Solution Provider Presentation
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Solution Provider Presentation
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15.20 – 16.20 Afternoon refreshments, Poster Presentation Sessions, One to One Meetings x2
16.20 – 16.50 Bioinformatics And Mapping Tools
CONFIRMED: Zhaohui Steve Qin, Associate Professor,
Department of Biostatistics, Emory University
Spatial Transcriptomics Analysis Pipeline
CONFIRMED: Guo-Cheng Yuan, Associate Professor, of
Computational Biology and Bioinformatics, Dana-
Farber Cancer Institute
Translation To Diagnostic And Therapeutic
Applications
CONFIRMED: Brian Dougherty, Executive Director of
Translational Medicine, AstraZeneca Oncology R&D
16.50 – 17.20 Cloud-Native Methods For Long Read SV Discovery In
Human Genomes
CONFIRMED: Kiran Garimella, Senior Computational
Scientist, Broad Institute
Tool Development to Enable Spatial Transcriptomics
Research
CONFIRMED: Yu-Hwa Lo, William SC Chang
Professor, Electrical and Computer Engineering, UCSD
Method for Dynamically Detecting Secretions from
Single Cells Using a Nanopore
CONFIRMED: Gregory Timp, Professor, Notre Dame
University
17.20 – 17.50 Whole Genome Sequencing in Cohort for
Cardiovascular Patients - Data Analysis Case Study
Using Nanopore Sequencing
CONFIRMED: Fritz Sedlazeck, Assistant Professor,
Human Genome Sequencing Center, Baylor College of
Medicine
ClampFISH And 3D Single-Cell Protein Atlas
CONFIRMED: Sara Rouhanifard, Assistant Professor,
Northeastern University
RNA Regulators Of Self-Renewal In Both Normal And
Leukemic Hematopoiesis
CONFIRMED: Michael Kharas, Lab Head, Kharas Lab,
Memorial Sloan Kettering Cancer Center
17.50 – 18.20 Developing Benchmarks for Challenging Variants With
Long Reads
RESERVED: Chi-Ming Li , Principal Scientist – Genome
Analysis Unit, Center of Excellence for NGS and Single
Cell Genomic Analysis
Spatial Cell Atlases with Next Generation In Situ
Sequencing • The “next generation in situ sequencing” (NGISS) has an
increased sensitivity and signal/noise and works on a larger
range of target RNA and sample types
• NGISS generates spatial cell atlases in high throughput and is
applicable on a range of tissue samples
• Spatial cell type maps on human brain tissue samples
CONFIRMED: Malte Kühnemund, CEO, CARTANA
Case Study: Pioneering Single Cell Technologies To
Advance Brain Repair
CONFIRMED: Ana Martin-Villalba, Professor, German
Cancer Research Centre
19.00 End of Day One & Networking Drinks
For more information please contact [email protected]
6th Annual Next Generation Sequencing & Single Cell Analysis USA Congress
Day Two – 8 April 2020
Next Generation Sequencing Single Cell Analysis
08.00 – 09.30 INTERACTIVE WORKSHOP: Accuracy, Cost And Coverage Of Short And Long Read
Sequencing
• Applications for long and short read
• Integration of short and long read technologies
• Comparison of Accuracy, Cost And Coverage Of Short And Long Read Sequencing
CONFIRMED:
Moderator: Stuart A. Scott, Associate Professor, Department of Genetics and
Genomic Sciences, Icahn School of Medicine at Mount Sinai, ,Division Head,
Pharmacogenomics, Director, Cytogenetics and Cytogenomics
Panellists:
Cynthia Morton, Director of Cytogenetics, Harvard University
James Willey, Professor of Medicine and Pathology, George Isaac Chair for Cancer
Research, University of Toledo
INTERACTIVE WORKSHOP: Spatial Transcriptomics
Spatial Transcriptomics allows the sequencing of the complete transcriptomes
from barcoded regions of intact tissue. The technology has the potential to
answer a wide range of biological questions concerning cellular function, but
analysis of the data presents a number of challenges which are not met by
existing analysis tools. The workshop aims to cover topics ranging from the
challenges of using Spatial Transcriptomics tools and technology in sample
preparation, data analysis and visualization. It also includes Mining the
transcriptome using spatial transcriptomics.
Day 2 Stream 1
PART 1: Long Read Sequencing and Short Read
Sequencing for Implementation of Genomic Medicine
Day 2 Stream 1: Single-Cell Analysis In Drug
Discovery and Development
Day 2 Stream 2: Single Cell Analysis: Overcoming
Challenges
09.30 – 10.00 Delivering Genomic-based Precision based Medicine
CONFIRMED: Stuart A. Scott, Associate Professor,
Department of Genetics and Genomic Sciences, Icahn
School of Medicine at Mount Sinai, Division Head,
Pharmacogenomics, Director, Cytogenetics and
Cytogenomics
Case Studies: Oncology, Immunotherapy,
Neurodegenerative, Autoimmune And Rare
Diseases Using Multi-Omics Approaches
CONFIRMED: Bin Li, Director, Computational
Biology, Takeda
Microfluidic Tools For Monitoring The Immune System
CONFIRMED: Joel Voldman, Professor of Electrical
Engineering, Associate Head, Electrical Engineering and
Computer Science, MIT
10.00 – 11.00 Morning Coffee & Refreshments, Poster Presentation Sessions, One to One Meetings x2
11.0 – 11.30 Solution Provider Presentation
Presentations on Long Read Platforms & Data Analysis
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Solution Provider Presentation
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Solution Provider Presentation
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For more information please contact [email protected]
6th Annual Next Generation Sequencing & Single Cell Analysis USA Congress Day Two – 8 April 2020
11.30 – 12.00 Solution Provider Presentation
Genome Visualization and Analysis
For sponsorship opportunities please contact
Solution Provider Presentation
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Solution Provider Presentation
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12.00 – 12.30 A Time To Sequence In Clinical Cytogenetics: The Need
For Nucleotide Resolution
CONFIRMED: Cynthia Morton, Director of Cytogenetics,
Harvard University
Case Study: Single-Nuclei RNAseq In Human Brain
Neurons
CONFIRMED: Xianjun Dong, Director of
Computational Neuroscience, Brigham and
Women's Hospital
Biological Network Analyses Of Single Cell Data To Learn
About Intercellular Regulatory Biology Of Tissues And
Diseases
CONFIRMED: Bruce Aronow, Professor, UC Department of
Pediatrics, Cincinnati Children's Hospital Medical Center
12.30 – 13.30 Lunch, Poster Presentation Sessions
13.30 – 14.00
NGS and Delivering Genomic Based Medicine (TBA)
CONFIRMED: James Willey, Professor of Medicine and
Pathology, George Isaac Chair for Cancer Research,
University of Toledo
Single Cell RNAseq In Drug Development
CONFIRMED: Jin Jen, Director, Sequencing Research,
Celgene
Panel Discussion – Choosing Among Alternative Single
Cell Protocols And Technologies
• 10x, CellSeq, NucSeq, ATAC-Seq, and Spatial Seq
Technologies
• Platform Options and Inter-technology comparisons
• Sampling approaches and the effects of
development, aging, disease on sample integrity
• Validation methodologies at the level of gene, cell,
tissue
• Disease profiling versus normal tissues
• How do alternative technologies provide distinct
biological insights into cell lineages, tissues,
diseases
Moderator: Bruce Aronow, Professor, UC Department of
Pediatrics, Cincinnati Children's Hospital Medical Center
CONFIRMED:
• Charles Wang, Director, Center for Genomics,
Professor, Department of Basic Sciences, Loma Linda
University School Of Medicine
• WADE DAVIS, Director Computational Genomics,
Genomics Research Center (GRC), Abbvie
For more information please contact [email protected]
6th Annual Next Generation Sequencing and Clinical Diagnostics & Single Cell Analysis Congress
Day Two – 8 April 2020
Part 2: Short and Long Read Sequencing – Applications in
the Clinic
Single-Cell Analysis In Drug Discovery and
Development
Single Cell Analysis: Emerging Trends and Technologies in
Single Cell Analysis
14.00 – 14.30 Sudden Cardiac Death Prevention With Molecular
Diagnosis
CONFIRMED: Rong Mao, Professor of Pathology,
University of Utah School of Medicine, Medical Director,
Molecular Genetics and Genomics, ARUP Laboratories
To Investigate The Transition And Diversity Spectrum
Of Innate Lymphoid Cells In Human Mucosal Tissues
By scRNA-seq
• Introduction to innate lymphoid cells (ILCs) and
its sub-classes
• RNA velocity to predict the future state of
individual cells
Transition among different ILC subsets by
CONFIRMED: Shanrong Zhao, Director, Computational
Biology and Bioinformatics, Pfizer Inc.
Gene Regulation (TBC)
CONFIRMED: Vladimir Kiselev, Informatics Team Leader,
Wellcome Trust Sanger Institute
14.30 – 15.00 Nature of Cell Free DNA in Cancer Patient Blood Samples
We have been investigating the nature of cell free (cf) DNA in
cancer patient blood samples. In particular looking for the
presence of mutations in the higher molecular weight cf-DNA
that is often found in cancer patient blood samples. Using a
new electrokinetic device (ACE chip, Biological Dynamics, San
Diego, CA) now allows sample to answer Multi-Omic analysis
of exosome and extracellular vesicle (EV) biomarkers as well
as cell free (cf) DNA and RNA from the “same” 20-50 µL blood,
plasma or serum sample.
CONFIRMED: Michael Heller, Professor, University of
California, San Diego, Distinguished Scientist - Knight
Cancer Institute at Oregon Health & Science University
(OHSU), Center for Cancer Early Detection and Research
Single Cell CRISPR + Single Cell RNAseq in Drug
Discovery = A Powerful Combination
• Challenges in CRISPR Pooled Screening
• Application of combination single cell CRISPR + Single
Cell RNAeq
• Examples of questions that can be addressed with
this approach
CONFIRMED: WADE DAVIS, Director Computational
Genomics, Genomics Research Center (GRC), AbbVie
Using Single Nucleotide Variations of Single-Cell RNA-Seq
to Identify Subpopulation and Genotype-phenotype Links
RESERVED: Lana Garmire, Director of Bioinformatics Core
and Associate Professor, University of Michigan
15.00 – 15.30 Afternoon Refreshments, Poster Presentation Sessions
15.30 – 16.00 NGS For Precision Surveillance Of Multidrug-Resistant
Organisms And Infection Control Practice
CONFIRMED: Hank Wang, Professor of Clinical Pathology
& Director of Microbiology, Virology & Molecular
Diagnostics Laboratories, Westchester Medical Center &
New York Medical College
Single Cell In Discovery For Immuno-oncology
CONFIRMED: Qu Zhang. Senior Scientist, MedImmune
Overcoming Bioinformatics Challenges
CONFIRMED: Rob Mitra, Alvin Goldfarb Distinguished
Professor of Computational Biology, Professor of
Genetics, MGI
For more information please contact [email protected]
6th Annual Next Generation Sequencing and Clinical Diagnostics & Single Cell Analysis Congress
Day Two – 8 April 2020
Part 2: Short and Long Read Sequencing – Applications
in the Clinic
Single-Cell Analysis In Drug Discovery and
Development
Single Cell Analysis: Emerging Trends and Technologies in
Single Cell Analysis
16.00 – 16.30 Molecular Diagnostics Development
RESERVED: Andrea Ferreira-Gonzalez, Chair of the
Molecular Diagnostics Division and Director of the
Molecular Diagnostics Laboratory, VCU Health
Single Cell Proteomics and Drug Discovery
CONFIRMED: David H. Perlman, Principal Scientist,
Proteomics and Target Discovery Lead, Merck
Research Labs Cambridge Exploratory Sciences Center
Develop Machine Learning Algorithms For Computational
Analysis Of Biological Sequences: DNA, RNA And Proteins.
Our Primary Focus Is On Prediction Of Protein-Coding
Genes And Regulatory Sites In Genomic DNA
CONFIRMED: Mark Borodovsky, Director, Center for
Bioinformatics & Computational Genomics, Georgia Tech
and Emory University
16.30 – 17.00 Applications in the Clinic Applications of Long Read
Sequencing in Oncology and Immuno- oncology
Exploring Tumor Microenvironment & Disease
Modeling Using Single Cell RNASeq
CONFIRMED: Kalpit Shah, Former Senior Research
Investigator, Bristol-Myers Squibb
Overcoming Bioinformatics Challenges
CONFIRMED: Lihua Julie Zhu, Professor and Head of
Bioinformatics Core, University of Massachusetts
17.00 - 17.30 Illuminating Bacterial Epigenomes to Characterize
Pathogens and Microbiome
Single-Nucleus RNA-Seq Study On Human Spinal
Cords From ALS Patients (And Control) For Target
Discovery
CONFIRMED: Dann Huh, Senior Scientist, Biogen
Dealing With Multi- omics Data Coming From Single Cell
Analysis
CONFIRMED: Joshua Campbell, Co-Director of the Single
Cell Sequencing Core and Assistant Professor, Boston
University
17.30 End Of Conference