Siemens Eclipse Cyclotron Development 2018 Users Meeting

Development Update

Siemens Eclipse Cyclotron

2018 Users Meeting

James H. Hinderer August 25, 2018

Unrestricted © Siemens Healthcare GmbH, 2018 MI-4098

What’s new for Siemens Cyclotrons?

Large Installed Base of Eclipse Cyclotrons

Large R&D Investment to Modernize Eclipse Cyclotron

Multiple Technology and Manufacturing Partnerships

New Cyclotron Service Support Offerings

Page 2 | Unrestricted © Siemens Healthcare GmbH, 2018 MI-4098

Operational excellence Dedicated service infrastructure

CSML Hub Singapore

APAC RSC Shanghai 1 FTE

SLC Hub Beijing

EU RSC Erlangen 5 FTE‘s

SLC CS HQ Shanghai 4 FTE‘s

CCS HSC Knoxville 6 FTE‘s

CSML Hub Frankfurt

CSML Hub Memphis

CCS Training Center Knoxville

USA RSC Knoxville 9 FTE‘s

Factory Trained Engineer (FTE)

Siemens customer care center • Call clarification & dispatch • Tech support • Remote diagnostics • Escalation to regional support center

(RSC)

Siemens customer service engineer • Factory trained and certified • Typical response time within ~24 hrs • Expert technical support provided by

headquarter support center (HSC)

Access to spare parts • 3 CSML global hubs • 1 SLC regional hub (Beijing)


Coming soon! Major updates for your Eclipse Cyclotron

The products/features (mentioned herein) are not yet commercially available. Due to regulatory reasons their future availability cannot be guaranteed. Data on file.

v5.0 Control System • Replaces the VME with a National Instruments cRIO controller • New modern user interface replaces Fix32 • 50% faster beam startup time and improved beam control • Strengthen system security with hardened Windows10 OS

v3.0 RF System • 12kW air-cooled RF system with 20% more power • High power RF tube with longer life • Digital controls and improved user feedback

High Output Ion Source • Updated internal penning source • Material and geometry changes to optimize H- ion production

New 18F Targetry Options • Aluminum target nose piece to replace Cu hex grid

for increased 18F yield

1

2

3

4


Modern user interface: v5.0 Cyclotron Control System Multiple new features to optimize performance

OLD - Fix32 UI NEW – v5.0 Control System UI

Operating System Windows XP Windows10

Beam Startup Time (post initialization) ~10min ~3min

Error/Warning Messages & PM notifications Yes

Beam control +/- 5uA +/- 1uA

Ion Source Positioning Manual Only

(hand controls) Auto (software)

& Manual

Target Pressure Check Yes.

To minimize blown targets

Beam SplitViewer Yes.

View history of beam splits

Automatic Data Logging

Yes. To Siemens SRS database

Automatic Extractor Foil Change Yes

X

X

X

X

X

The products/features (mentioned herein) are not yet commercially available. Due to regulatory reasons their future availability cannot be guaranteed. Data on file. Page 5 | Unrestricted © Siemens Healthcare GmbH, 2018 MI-4098

Eclipse v3.0 high power RF System Delivering 20% more RF power

RF Controller

New firmware Easier setup & better diagnostics

Digital display Higher reliability & more information

Intermediate Power Amp (IPA)

Digital display Higher reliability & more information

Higher power More headroom to drive final amp

No matching network Simplifies setup/reduces service complexity

12kW Final Power Amp

Indexed tuning Easier tuning

50Ω Final Input Simplifies setup

Increased structural strength Reduce failure rate and shipping damage

Increase output to 12 kW Increased headroom = fewer failures

RF Cabinet

High voltage power supply Increased output to support higher-output final amplifier


New High Power RF Cable with v3.0 RF System Rated at 37kW

The products/features (mentioned herein) are not yet commercially available. Due to regulatory reasons their future availability cannot be guaranteed. Data on file.

Flexibility Very Good

Attenuation Medium

Power Handling Very High

Temperature High


Updated internal penning Ion Source

Modified Top Flange Assembly

Modified Cooling System

Modified Emitter Housing

Anode/Puller & Cathode Changes


Internal source part changes Siemens partnered with D-Pace for source investigation

Description Test #

Arc Current

(A)

Arc Voltage

(kV)

Arc Power (kW)

Bias Voltage (kV)

Bias Current

(mA)

Total Target Current (μA)

Post to Foil

Trans. %

BOP (μA)

Target Current/ Arc Power

(Bigger is Better)

Cesium (Cs pill in lower cathode) 74 0.275 0.423 0.116 17.98 9.87 154.63 20.3% 925 1331

Anode, Threaded, Moly 67 0.264 0.526 0.139 17.65 5.93 153.96 18.8% 1050 1109

-10% Aperture Anode & Puller 40 0.271 0.566 0.154 17.20 4.75 152.37 20.6% 902 993

Standard Baseline Equipment 36 0.272 0.575 0.156 17.40 6.42 143.95 20.6% 840 923

The products/features (mentioned herein) are not yet commercially available. Due to regulatory reasons their future availability cannot be guaranteed. Data collected by Siemens Healthineers. Data on file. Page 9 | Unrestricted © Siemens Healthcare GmbH, 2018 MI-4098

Low work function for cesium = improved performance

Source: Scrivens, R.; “Electron and ion source for particle accelerators”, CERN, Geneva, Switzerland.

Cs Pill

Table 1: Parameters of sample cathode materials [1]

Parameters for mixed oxide (SrO/BaO) and CsO on W substrate depend critically on the the mixture and activation. Typical values are given.


Surface production of H- optimized with design changes Arc current fixed @ 0.27Amps for test cases

Target current starts at dual ~74µA and stays there.


New options for 18F HP Target Removal of hex grid gives increased saturation yield

Current design uses a copper nose piece with hex grid for Havar window support

• Hex grid prevents major window failure but copper gets highly activated which increases exposure when rebuilding target

Aluminum nose piece without hex grid option available • Aluminum doesn't get activated, but higher risk of window failure causing

distribution of activity and activated Havar material within the cyclotron– avoided by diligent PM schedule

Copper Spacer w/ Hex Grid (Stock)

Aluminum Spacer w/o Hex Grid


Enable more today with new Eclipse upgrades

• Baseline upgrade package with new v5.0 control system

• Lays the foundation for your needs now and into the future

• High power RF system with an updated ion source for 150uA of total target beam current

• Increase your 18F production by 25%

Eclipse VIEW

Eclipse HPlus

The products/features (mentioned herein) are not yet commercially available. Due to regulatory reasons their future availability cannot be guaranteed. Data provided from site runs at PETNET Raleigh-Durham, NC, USA location. Page 13 | Unrestricted © Siemens Healthcare GmbH, 2018 MI-4098


First RDS111/Eclipse Cyclotron installed at LBL in August 1996

Page 15 | Unrestricted © Siemens Healthcare GmbH, 2018 MI-4098 Image courtesy of Lawrence Berkley National Lab - https://berkeleynature.wordpress.com/tag/the-big-c/

https://berkeleynature.wordpress.com/tag/the-big-c/






”Siemens Healthineers” is considered a brand name. Its use is not intended to represent the legal entity to which this product is registered. Please contact your local Siemens organization for further details.

Unrestricted © Siemens Healthcare GmbH, 08.2018 MI-4098

James H. Hinderer Sr. Manager, R&D Cyclotron and Chemistry Solutions Molecular Imaging 810 Innovation Drive Knoxville, TN USA 37932 USA P +1 865-218-1669 E [email protected]

Thank You!

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Siemens Eclipse Cyclotron Development 2018 Users Meeting