24
0 50 100 150 200 250 300 350 400 450 o min 45 min 65 min Glutathione (nm oles/m g protein) Controls Practioners 0 0.5 1 1.5 2 2.5 o min 45 min 65 min Catalaseactivity(units/mgprotein/min) Controls Practioners 0 2 4 6 8 10 12 14 16 o min 45 min 65 min SODlevels(units/m l) Controls Practioners

Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Embed Size (px)

Citation preview

Page 1: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

0

50

100

150

200

250

300

350

400

450

o min 45 min 65 min

Glu

tath

ione

(nm

oles

/mg

prot

ein)

Controls

Practioners

0

0.5

1

1.5

2

2.5

o min 45 min 65 min

Cata

lase

activ

ity (u

nits

/mg

prot

ein/

min

)

Controls

Practioners

0

2

4

6

8

10

12

14

16

o min 45 min 65 min

SOD

leve

ls (u

nits

/ml)

Controls

Practioners

Page 2: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Sharma H, Sen S, Singh A, Bhardwaj NK,

Kochupillai V and Singh N.

Sudarshan Kriya practitioners exhibit better

antioxidant status and lower blood lactate levels

Biological Psychology

63: 281 - 291, 2003.

Page 3: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

SK & P : Effect : Immune system NK cells : 3 groups

• Those practising SK and P x at least 2 years

• Normal controls

• Cancer patients in remission Cancer patients in remission

• Controls Vs those practicing SK & P

NK cells : baseline, after 3 and 6 months. S.N. Das, Additional Prof., Biotechnology, AIIMS

Page 4: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

NK cells : Results

NK cells significantly higher in

SKY teachers Vs

normal & cancer patients (p<0.001)

Flowcytometry: N K Cells in P B

0

5

10

15

20

25

30

Normal subjects AOL teachers cancer aptients

% o

f cells

N K C ells in study & contro l arm

0

5

10

15

20

25

1 2 3 4

Sampling time (weeks)

% N

K ce

lls

Study arm

Control arm

Cancer patients in remission

Control Vs

practitioners of SK & P Vs

cancer pts in remission

Page 5: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Increase in NK cells and antioxidant defence

• May protect or delay the onset of several diseases

specifically age related diseases including cancer

• May slow down cancer progression

Page 6: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

SK & P : tobacco Cessation : 82 subjects

Day 6 : 53 / 82 = 65%

Month 2 : 63 individuals FU

23 Tobacco free

23/82 = 28%

Month 6 : 34 individuals FU

17 Tobacco free

17 /82 = 21%

Page 7: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Tobacco cessation through SK & P

• Cost effective

• No side effects

• Durable

• Urge to smoke disappears

• No effort or supervision required

Page 8: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Publication

Kochupillai V, Kumar P, Singh D et al.

Effect of rhythmic breathing (Sudarshan Kriya and Pranayam) on immune functions and tobacco addiction.

Annals New York Acad of Sciences. 1-11: 2005

Page 9: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Cholesterol study: Bangalore Medical

College Effect of Sudarshan Kriya Practise on

Serum Cholestrol

0

50

100

150

200

250

Normal 7 day SK 45 day SK

Ch

ole

stro

l (m

g%

)

Effect of Sudarshan Kriya Practise on Serum LDL Cholesterol

74.72

91.75

118.32

0

20

40

60

80

100

120

140

160

180

Normal 7 day SK 45 day SK

LD

L C

ho

lest

ero

l (m

g%

)

Effect of Sudarshan Kriya Practise on Serum HDL Cholesterol

51.5146.55

43.17

0

10

20

30

40

50

60

70

Normal 7 day SK 45 day SK

HD

L C

ho

lest

ero

l (m

g%

)

Total Cholesterol decreased

HDL increased (Good Cholesterol)

LDL decreased

(Bad Cholesterol)

Dr. Geetha

Page 10: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Tata Institute of Social Sciences: Research

• Participants: Management level

• Ambit corporate finance, Bacardi, Cadbury’s, Indian

oil, Mukand Steel, NTCP, Rallis India, Strategic

capital securities, Tata chemicals, World bank groups,

WHO Transasia Biochemicals

• Total participants: 543

underwent AOL workshop and learnt SK & P

Page 11: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Tata Institute Social Science: Research (Contd)

Improved state of mind= 88%

Improvement in dealing

with people = 60%

Handled stressful situation

better = 58%

Practicing SK & P:

Regularly = 58%

Recommended AOL

course to others = 60%

Page 12: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Health & Spirituality

• SK & P and meditation (spiritual practices):

– elimination of stress, anxiety

– allow free flow of neuropeptides and receptors:

molecules of emotions

• Better Immune status and antioxidant defense

• Freedom from addiction (tobacco & alcohol)

• Healthier body and healthier mind

Page 13: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

World Conference : Expanding Paradigms:

Science, Consciousness and Spirituality

February 24th & 25th 2006

Summary : Research Presentations

Page 14: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

SKY : Wellness effect 109 subjects 56 SKY vs 53 control (relaxed x 15 min) After 6 weeks of practice SKY gr • Lower anxiety, depression and stress • Higher degree of optimism • Perceived the practices as a positive event • Strong relaxation response – stress reduction Dr. Fahlri,

Prof. Molecular and Cell Biology, Univ. of Oslo, Norway

Page 15: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

SK : Effect on gene expression

• SK affects stress related signaling/ metabolic pathways

• 3 fold higher levels of glutathione in SKY practitioners

• Also higher levels of Catalase, glutathione N transferase and

glutathione peroxidase in RNA in SKY practitioners as

observed by RT – PCR.

• Increase in HTERT in SK practitioners : indicates delayed

senescence – longer life span

• Decrease in beta 2, C Myc and C-fos –

Suggests better protection against cancer

Dr. Neeta Singh, AIIMS

Page 16: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

SKY : Heart rate variability

• Improved heart rate variability within 6 days of practice

of SK and P

Dr. Narendra Bhardwaj &

Dr. KK Deepak,

Prof. Physiology, AIIMS

Page 17: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Post Traumatic stress disorder

• Combination of Asanas, Pranayam,

meditation, yoga nidra, Chanting,

Reflection on yoga philosophy etc.

highly efficient, cheap, safe and self

administrable processes

• Multi component yoga intervention

(MCY1) most – effective Dr. Janis Carter Psychiatrist, Brisbane, Australia

Page 18: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Breath, water and sound (BWS) program : PTSD

• BWS program offered to tsunami victims

– 80 subjects each

• BWS program

• BWS & Traumatic Incidence Reduction

• controls

• BWS group significantly reduced

scores for PTSD and depression

– Addition of TIR showed no further

benefits

Teresa Descilo,

Trauma Specialist,

Executive Director Victim Service Center, Miami, FL

Page 19: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

SKY : effect on clinicians • American oncologists: burnout feeling : 56 %

• Dealing with dying patients,

• Breaking bad news to very sick

• End of life issues

• MD Anderson Cancer Center - AOL program

– Faculty

• Favorable effects

• Greater sense of well being

• Release of tension and anxiety

• Feeling of more control over their work

Wendell Taylor, Lata More, PhD.Janis Apted, MLS

Univ. of Texas, Health Science Center, Houston

Page 20: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Were there any changes in the following?

Worse No Change

Slightly Better

Better Much Better

Anxiety/ Tension 0% 4 % 25 % 38 % 33 %

Ability to Stay Calm 0% 4% 25 % 42 % 29 %

Mood 0% 12 % 12 % 50 % 25 %

Ability to Focus 0% 12 % 38 % 46 % 4 %

Relationships Outside Work

0% 21 % 38 % 29 % 12 %

Feelings of Stress 0% 4 % 21 % 38 % 38 %

Sleep 0% 25 % 25 % 33 % 17 %

Anger/ Frustration 0% 17 % 25 % 42 % 17 %

Closeness w/ Coworkers

0% 38 % 33 % 21 % 8 %

Optimism 0% 12 % 33 % 29 % 25 %

Page 21: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

SKY : Effect on occupational stress and anxiety : Executive

and othersSixty software workers vs. controls

• Significant reduction: anxiety score • Improvement in stress coping skills

Dr. Vedamurthachar

NIMHANS, Bangalore, India

Page 22: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

SKY : Breast Cancer

• Two independent studies – Arielle Warner – Palo Alto,CA– Manju Sengar : AIIMS, Delhi

• Significant improvement (p< 0.0001) – Quality of life – Spiritual well being – Positive state of mind– Perceived stress – Decreased stress symptoms – Increase in NK cells – Side effect of chemotherapy reduced

Page 23: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Perfect HealthBody without disease

Breath without quiver

Mind without stress

Intellect without obsession

Memory without trauma

Ego which can accept all

self without sorrow

H H Sri Sri Ravi Shankar

Page 24: Sharma H, Sen S, Singh A, Bhardwaj NK, Kochupillai V and Singh N. Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate

Sri Sri Global Meditating Doctor’s Association

(Sri Sri GMDA)

Forms available

Life membership Rs. 500/-