Section X 1/31

Senior-supervisors within the doctoral studies at the MUV Name of supervisor (LAST NAME, First name): Helbich, Thomas Organizational unit and subunit: Department of Biomedical Imaging and Image-guided Therapy, Division of General and Pediatric Radiology Studies (N094, N790): N094 Thematic Program: Medical Imaging Funding source for students to be supervised: EU-Grant FP7-ICT-2011-9;#601040, provided that the doctoral student is not already employed (full-time, 40h/week) at the Medical University of Vienna Third-party funding (select a max. of 5 starting with the most recent)

Period Organization (eg. FWF) Short title €/year

2015-

2016

EU-Grant: FP7-ICT-2011-9;#601040

Virtual Physiological Human: Personalized

Predictive Breast Cancer Therapy Through

Integrated Tissue Micro-Structure Modeling:

Member of the consortium

120.000

2015-

2017

CDL Christian Doppler Labour: Medical Radiation

Research for Radiation Oncology; WP 3 -

Functional pre-clinical and clinical imaging;

WP-Leader

100.000

2013-

2015

CCC-MUW Simultaneous multiparametric PET-MRI:

Improved diagnosis and advanced

radiotherapy treatment planning of prostate

cancer

46.000

2015-

2017

Science Fund of the

Austrian National Bank

Magnetic Resonance Tumor Vessel Architecture Mapping as a Novel Imaging Biomarker for the Assessment of Breast Tumors

65.000

Local, national and international co-operations (select a max. of 5 starting with the most recent)

Name (Last-, Firstname) Title of project

Section X 2/31

Current doctoral students (PhD)

Name (Last-, Firstname) Title of project

Spick Claudio Diffusion weighted imaging of the breast

Wengert Georg Automated quantitative MR breast density measurment

system

Former doctoral students (select a max. of 5 starting with the most recent)

Name (Last-, Firstname) Title of the doctoral thesis

Former diploma students (select a max. of 5 starting with the most recent)

Name (Last-, Firstname) Title of the diploma thesis

Stiglbauer Alexander Molecular imaging with ultrasound in animal models

Nagl Georg Die Wertigkeit der Tomosynthese bei Brustläsionen

Luft Nikolaus Final results of the Austrian imaging screening trial for familiar

breast cancer

Vogl Wolf Dieter Multiparametrische CAD bei MRT der Brust

Linhart Hans-Goerg Wertigkeit der c-Acetat PET im Vergleich zu PET7CT Other supervisions (select a max. of 5 starting with the most recent)

Name (Last-, Firstname) Kind of Supervision

Katja Pinker Clinical and research training (breast imaging), provision of

infrastructure, multiple publications

Christopher Riedl Clinical and research training (breast imaging), provision of

infrastructure, multiple publications

Section X 3/31

Julia Frühwald-Pallamar Clinical and research training (breast imaging), provision of

infrastructure, multiple publications

Publications with trained and supervised individuals as listed above as first-authors (reference all authors and provide the exact citation; the name of the applicant in bold letters; corresponding author underlined; e.g.: O'Connor V, El Far O, Bofill-Cardona E, Nanoff C, Freissmuth M,

Karschin A, Airas JM, Betz H, Boehm S. Science. 1999 Nov 5;286(5442):1180-4.) Spick C, Szolar DH, Baltzer PA, Tillich M, Reittner P, Preidler KW, Pinker-Domenig K, Helbich TH. Rate of malignancy in MRI-detected probably benign (BI-RADS 3) lesions. AJR Am J Roentgenol. 2014 Mar;202(3):684-9. Pinker K, Baltzer P, Bogner W, Leithner D, Trattnig S, Zaric O, Dubsky P, Bago-Horvath Z, Rudas M, Gruber S, Weber M, Helbich TH. Multiparametric MR Imaging with High-Resolution Dynamic Contrast-enhanced and Diffusion-weighted Imaging at 7 T Improves the Assessment of Breast Tumors: A Feasibility Study. Radiology. 2015 Aug;276(2):360-70. Pinker K, Bogner W, Baltzer P, Karanikas G, Magometschnigg H, Brader P, Gruber S, Bickel H, Dubsky P, Bago-Horvath Z, Bartsch R, Weber M, Trattnig S, Helbich TH. Improved differentiation of benign and malignant breast tumors with multiparametric 18fluorodeoxyglucose positron emission tomography magnetic resonance imaging: a feasibility study. Clin Cancer Res. 2014 Jul 1;20(13):3540-9. Pinker K, Bogner W, Baltzer P, Gruber S, Bickel H, Brueck B, Trattnig S, Weber M, Dubsky P, Bago-Horvath Z, Bartsch R, Helbich TH. Improved diagnostic accuracy with multiparametric magnetic resonance imaging of the breast using dynamic contrast-enhanced magnetic resonance imaging, diffusion-weighted imaging, and 3-dimensional proton magnetic resonance spectroscopic imaging. Invest Radiol. 2014 Jun;49(6):421-30. Pinker K, Bogner W, Baltzer P, Trattnig S, Gruber S, Abeyakoon O, Bernathova M, Zaric O, Dubsky P, Bago-Horvath Z, Weber M, Leithner D, Helbich TH. Clinical application of bilateral high temporal and spatial resolution dynamic contrast-enhanced magnetic resonance imaging of the breast at 7 T. Eur Radiol. 2014 Apr;24(4):913-20. doi: 10.1007/s00330-013-3075-8. Fruehwald-Pallamar J, Jantsch M, Pinker K, Hofmeister R, Semturs F, Piegler K, Staribacher D, Weber M, Helbich TH. Teleradiology with uncompressed digital mammograms: clinical assessment. Eur J Radiol. 2013 Mar;82(3):412-6. Riedl CC, Luft N, Bernhart C, Weber M, Bernathova M, Tea MK, Rudas M, Singer CF, Helbich TH. Triple-modality screening trial for familial breast cancer underlines the importance of magnetic resonance imaging and questions the role of mammography and ultrasound regardless of patient mutation status, age, and breast density. J Clin Oncol. 2015 Apr 1;33(10):1128-35.

Section X 4/31

Headline and description of the planned project: Virtual Physiological Human: Personalized Predictive Breast Cancer Therapy Through

Integrated Tissue Micro-Structure Modeling

Breast cancer is frequent and life threatening, but curable if detected early. Early detection

and comprehensive characterisation of findings require optimized imaging and image

understanding to maximise detection of significant disease while preventing overdiagnosis.

Personalised predictive modeling of breast cancer allows treatment stratification, preventing

unnecessary and unsuccessful treatments. VPH-PRISM addresses these key topics with

integrated multidisciplinary, multi-scale ICT modeling of breast tissue microstructure in the

context of environmental, genetic, and clinical factors.

Key challenges include establishment of combined biomarkers from the automated analysis

and spatial correlation of digital pathology and advanced breast imaging. Tissue

characterisation includes the peritumoral stroma, a key in tumour progression and therapy

response. Comprehensive clinical breast cancer phenotypes are extracted from

prospectively collected multidisciplinary data. Interactions of environmental and genetic

factors with specific breast tissue patterns are analysed in three large ongoing population-

based imaging cohorts. A standard breast model enables efficient, combined statistical

modeling of sparsely sampled and heterogeneous, large-scale data across disciplines,

scales, structures, time and patients.

Using the developed tools and models, and the data collected, we will:

• improve estimates of tumour spread to aid surgery and assess chemo- and

radiotherapeutic response

• optimise multi-modal imaging methods through biophysical forward modeling of image

formation for more

efficient phenotyping and imaging biomarkers

• predict personal risks for cancer progression and select optimal treatment strategies

VPH-PRISM will provide a proof of concept for multidisciplinary model based discovery of

environment-tissue interactions, quantitative drug efficacy assessment, surgery planning,

and treatment outcome prediction at early and advanced stages of breast cancer.

Section X 5/31

Curriculum Vitae

Name Thomas H. Helbich

Address: Schwindgasse 10/Top 15, 1040 Vienna

Personal Data

Date of Birth: 12.10.1963

Place of Birth: Hainburg a.d.Donau

Nationality Austria

Education See attached

from – to 1983-11/1989 Dr. med. univ. (MUW)

Add lines if needed

Career History See attached

Since 10/2008 Professor of Radiology, Medical University of Vienna

(MUW) Career History:

01.06.1990 – 31.07.1990 Internship, Heeresspital Wien 01.08.1990 – 31.07.1996 Residence, Dapartment of Radiology Medical University of Vienna, Rotation since 31.07.1996 Board certified Radiologist „Facharzt fuer

Medizinische Radiologie-Diagnostik“ since 1992 “Universitaetslektor”; Medical University of

Vienna 01.10.1996 – 10.06.1998 Research fellow, Department of Radiology

Center for Pharmaceutical and Molecular Imaging (CPMI), University of California San Francisco, USA

since 01.06.1998 Staff Position, Department of Radiology; Medical University of Vienna

since 20.05.1999 Habilitation „Universitaetsdozent fuer Radiologie“ Habilitationsschrift: „Stereotaktische und Ultraschall gezielte Brustbiopsie: experimentelle und klinische Untersuchung zur Optimierung der Technik“

10.01.1999 Associate Professor of Radiology; Medical University of Vienna

10.01.2000 – 04.30.2007 Chief Working group “Oncologic Imaging” (Women`s Imaging, Molecular Imaging) Department of Radiology; Surgical Diagnostic Division; Medical University of Vienna

Section X 6/31

01. 06.1999 – 31. 12.2001 Chief Senior Physican „Multidetector CT“: Department of Radiology; Surgical Diagnostic Division; Medical University of Vienna

01. 01.2002 – 30. 06.2002 Staff Rotation Angiography-Interventional Radiology (J. Lammer, MD, Prof. of Radiology, Vienna, General Hospital, Medical University of Vienna)

01.07.2002 – 30.04.2007 Chief Senior Physican MRI and Gynecological Imaging incl. Mammography: Department of Radiology; Surgical Diagnostic Division; Medical University of Vienna

01.12.2005 – 30.04.2007 Acting Chief: Department of Radiology; Surgical Diagnostic Division; Medical University of Vienna

01.01.2006 – 04.30.2007 Chief Qualitymanagement; Department of Radiology; Surgical Diagnostic Division; Medical University of Vienna

12.01.2005 – 04.30.2007 Vice-Division Head; Department of Radiology; Surgical Diagnostic Division; Medical University of Vienna

05.01.2007 – 09.30.2008 Professor of Radiology Chief of Breast Imaging Department of Radiology (PMH/MSH/UCH) University of Toronto, Ontario, Canada Since 10.01.2008 Professor of Radiology Vice Chair of the Department Director of Molecular and Gender Imaging Department of Biomedical Imaging and Image-

guided Therapy Medical University of Vienna

Vice Chair Division of General and Pediatric Radiology, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna

List of publications: Original articles:

1. Mallek R, Mostbeck G, Walter R, Helbich TH, Tscholakoff D. Duplex sonography of the celiac trunk and superior mesenteric artery: angiography correlation. Vasa Suppl. 1990;30:128. Impact: 0.230

2. Mallek R, Mostbeck GH, Kain R, Sunder-Plassmann G,

Helbich TH, Tscholakoff D. Polyetiology of renal allograft dysfunction. Does calculation of the resistive index still make sense? Acta Radiol. 1992 Sep;33(5):434-9. Impact: 0.736

Section X 7/31

3. Helbich TH, Stiglbauer R, Breitenseher M, Eichler I, Götz M, Schurawitzki H. High-resolution computed tomography of the lung in young patients with cystic fibrosis. Radiologe. 1993 Mar;33(3):142-6. Impact: 0.495

4. Helbich TH, Breitenseher M, Heinz-Peer G, Vergesslich K, Granditsch G, Kainberger

F. Color Doppler ultrasound of gallbladder varicose veins in children. A rare sign of portal hypertension. Ultraschall Med. 1994 Jun;15(3):126-30. Impact: 0.604

5. Heinz-Peer G, Helbich TH, Barnas U, Mayer G, Muehlbacher F, Mostbeck GH.

Renal cell carcinomas of donor origin in two kidney transplants from a single donor. Transplantation. 1995 Mar 27;59(6):912-3. Impact: 3.568

6. End A, Helbich TH, Wieser W, Dekan G, Klepetko W.

The pulmonary nodule after lung transplantation. Cause and outcome. Chest. 1995 May;107(5):1317-22. Impact: 3.418

7. Helbich TH, Mostbeck GH, Zontsich T, Heinz-Peer G, Cervenka P, Wohlschlager H,

Fitzal P, Wolf G. The experiences of a hospital radiology department with outside referrals for the preoperative marking of suspicious breast lesions. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1995 Jun;162(6):492-6. Impact: 0.901

8. Breitenseher M, Trattnig S, Kukla C, Gaebler C, Helbich TH, Haller J, Imhof H.

Trauma of the ligaments and tendons. Examination technique and detection in MRI. Radiologe. 1995 Jul;35(7):456-62. Impact: 0.495

9. Trattnig S, Breitenseher M, Haller J, Helbich TH, Gaebler C, Imhof H.

Tarsal tunnel syndrome. MRI diagnosis. Radiologe. 1995 Jul;35(7):468-72. Impact: 0.495

10. Breitenseher M, Graninger W, Helbich TH.

Case report: giant synovial osteochondromatosis in association with acromegaly. Clin Radiol. 1995 Sep;50(9):657-9. Impact:1.114

11. Heinz-Peer G, Mostbeck GH, Banyai S, Helbich TH, Turetschek K, Kainberger F.

Malignant neoplasms after kidney transplantation: value of an annual radiological screening program. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1995 Sep;163(3):250-5. Impact: 0.901

12. Pokieser P, Wohlschlager H, Hirschl MM, Seidler D, Böhm P, Kettenbach J, Helbich

TH, Laggner A, Scheiber V, Mostbeck GH. Evaluation system in assessing radiological examinations of clinical significance

Section X 8/31

for the patient. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1996 Jan;164(1):42-6. Impact: 0.901

13. Youssefzadeh S, Eibenberger K, Helbich TH, Jakesz R, Wolf G.

Use of resistance index for the diagnosis of breast tumours. Clin Radiol. 1996 Jun;51(6):418-20. Impact: 1.114

14. Helbich TH, Dantendorfer K, Mostbeck GH, Schick S, Wunderbaldinger P,

Amering M, Alexandrowicz R, Wolf G. Randomized comparison of sitting and prone positions for stereotactic fine-needle aspiration breast biopsy. Br J Surg. 1996 Sep;83(9):1252-5. Impact: 2.890

15. Helbich TH, Kainberger F, Erlacher L, Machold K.

Baker-Zysten: Sonographische Diagnostik Rheumatology in Europe 1997;26:100-4. Impact: 0.0

16. Wolf G, Helbich TH.

Mammographisches Erscheinungsbild des ductalen Carcinoma in situ und des multizentrischen Carcinoms. Acta Chirurgica Austriaca. 1997;3:111-4. Impact: 0.600

17. Helbich TH, Wojnarovsky C, Wunderbaldinger P, Heinz-Peer G, Eichler I, Herold CJ.

Pulmonary alveolar microlithiasis in children: radiographic and high-resolution CT findings. AJR Am J Roentgenol. 1997 Jan;168(1):63-5. Impact: 2.179

18. Helbich TH, Mallek R, Madl C, Wunderbaldinger P, Breitenseher M, Tscholakoff D,

Mostbeck GH. Sonomorphology of the gallbladder in critically ill patients. Value of a scoring system and follow-up examinations. Acta Radiol. 1997 Jan;38(1):129-34. Impact: 0.736

19. Dantendorfer K, Amering M, Bankier A, Helbich TH, Prayer D,

Youssefzadeh S, Alexandrowicz R, Imhof H, Katschnig H. A study of the effects of patient anxiety, perceptions and equipment on motion artifacts in magnetic resonance imaging. Magn Reson Imaging. 1997;15(3):301-6. Impact: 1.208

20. Staudenherz A, Abela C, Niederle B, Steiner E, Helbich TH, Puig S, Kaserer K,

Becherer A, Leitha T, Kletter K. Comparison and histopathological correlation of three parathyroid imaging methods in a population with a high prevalence of concomitant thyroid diseases. Eur J Nucl Med. 1997 Feb;24(2):143-9. Impact: 2.564

Section X 9/31

21. Kelkar PS, Helbich TH, Becherer A, Rudas M, Lehner R, Mostbeck GH. Solitary breast metastasis as the first sign of a squamous cell carcinoma of the cervix: imaging findings. Eur J Radiol. 1997 Feb;24(2):159-62. Impact: 0.537

22. Helbich TH, Becherer A, Trattnig S, Leitha T, Kelkar P, Seifert M, Gnant M,

Staudenherz A, Rudas M, Wolf G, Mostbeck GH. Differentiation of benign and malignant breast lesions: MR imaging versus Tc-99m sestamibi scintimammography. Radiology. 1997 Feb;202(2):421-9. Impact: 4.753

23. Helbich TH, Wunderbaldinger P, Plenk H, Deutinger M, Breitenseher M, Mostbeck

GH. The value of MRI in silicone granuloma of the breast. Eur J Radiol. 1997 Feb;24(2):155-8. Impact: 0.537

24. Breitenseher MJ, Haller J, Kukla C, Gaebler C, Kaider A, Fleischmann D, Helbich

TH, Trattnig S. MRI of the sinus tarsi in acute ankle sprain injuries. J Comput Assist Tomogr. 1997 Mar-Apr;21(2):274-9. Impact: 1.322

25. Helbich TH, Becherer A, Leitha T, Mostbeck GH.

Differentiation of benign and malignant breast lesions: MR imaging versus Tc-99m sestamibi scintimammography. Radiology. 1997; 205:285-6 (letter). Impact: 4.753

26. Helbich TH, Mayr W, Schick S, Youssefzadeh S, Rudas M, Taucher S, Wagner T,

Kelkar P, Wolf G, Thurnher M, Mostbeck GH. Coaxial technique: approach to breast core biopsies. Radiology. 1997 Jun;203(3):684-90. Impact: 4.753

27. Mueller M, Mader RM, Steiner B, Steger GG, Jansen B, Gnant M, Helbich TH,

Jakesz R, Eichler HG, Blöchl-Daum B. 5-fluorouracil kinetics in the interstitial tumor space: clinical response in breast cancer patients. Cancer Res. 1997 Jul 1;57(13):2598-601. Impact: 7.690

28. Kohlberger P, Helbich TH, Schaller A.

Delivery following surgically treated sacrococcygeal teratoma in the mother. Z Geburtshilfe Neonatol. 1997 Jul-Aug;201(4):148-51. Impact: 0.312

29. Wunderbaldinger P, Helbich TH, Dantendorfer K, Mostbeck GH, Turetschek K,

Memarsadeghi M, Amering M, Alexandrowicz R, Wolf G. Sitting or supine stereotaxic core biopsy of the breast? A comparison based on a randomized, prospective study. Radiologe. 1997 Aug;37(8):629-35.

Section X 10/31

Impact: 0.495

30. Becherer A, Helbich TH, Staudenherz A, Jakesz R, Kubista E, Lehner R, Rudas M, Teleky B, Kletter K, Leitha T. The diagnostic value of planar and SPET scintimammography in different age groups. Nucl Med Commun. 1997 Aug;18(8):710-8. Impact: 1.028

31. Trattnig S, Breitenseher M, Kontaxis G, Helbich TH, Rand T, Imhof H.

GRASE: ultra-fast turbo gradient spin-echo sequence. A new approach to fast MR imaging of the musculoskeletal system. Acta Radiol. 1997 Sep;38(5):880-4. Impact: 0.736

32. Gasche C, Aslanidis C, Kain R, Exner M, Helbich TH, Dejaco C, Schmitz G, Ferenci

P. A novel variant of lysosomal acid lipase in cholesteryl ester storage disease associated with mild phenotype and improvement on lovastatin. J Hepatol. 1997 Oct;27(4):744-50. Impact: 4.816

33. Thurnher MM, Thurnher SA, Fleischmann D, Steuer A, Rieger A, Helbich TH,

Trattnig S, Schindler E, Hittmair K. Comparison of T2-weighted and fluid-attenuated inversion-recovery fast spinecho MR sequences in intracerebral AIDS-associated disease. AJNR Am J Neuroradiol. 1997 Oct;18(9):1601-9. Impact: 1.869

34. Youssefzadeh S, Eibenberger K, Helbich TH, Dorffner R, Dantendorfer K,

Breitenseher M, Wolf G. Reduction of adverse events in MRI of the breast by personal patient care. Clin Radiol. 1997 Nov;52(11):862-4. Impact: 1.114

35. Trattnig S, Breitenseher M, Pretterklieber M, Kontaxis G, Rand T, Helbich TH, Imhof

H. MR-guided joint puncture and real-time MR-assisted contrast media application. Acta Radiol. 1997 Nov;38(6):1047-9. Impact: 0.736

36. Helbich TH, Rudas M, Haitel A, Kohlberger PD, Thurnher M, Gnant M,

Wunderbaldinger P, Wolf G, Mostbeck GH. Evaluation of needle size for breast biopsy: comparison of 14-, 16-, and 18-gauge biopsy needles. AJR Am J Roentgenol. 1998 Jul;171(1):59-63. Impact: 2.179

37. Wolf G, Helbich TH.

Results of stereotactic guidance of breast excisional biopsy versus stereotactic core biopsy in occult breast lesions. Wien Med Wochenschr. 1998;148(14):316-20. Impact: 0.0

Section X 11/31

38. Trattnig S, Huber M, Breitenseher M, Trnka HJ, Rand T, Kaider A, Helbich TH, Imhof H, Resnick D. Imaging articular cartilage defects with 3D fat-suppressed echo planar imaging: comparison with conventional 3D fat-suppressed gradient echo sequence and correlation with histology. J Comput Assist Tomogr. 1998 Jan-Feb;22(1):8-14. Impact: 1.322

39. Helbich TH, Breitenseher M, Trattnig S, Nehrer S, Erlacher L, Kainberger F.

Sonomorphologic variants of popliteal cysts. J Clin Ultrasound. 1998 Mar-Apr;26(3):171-6. Impact: 0.573

40. Wagner TM, Möslinger RA, Muhr D, Langbauer G, Hirtenlehner K, Concin H, Doeller

W, Haid A, Lang AH, Mayer P, Ropp E, Kubista E, Amirimani B, Helbich TH, Becherer A, Scheiner O, Breiteneder H, Borg A, Devilee P, Oefner P, Zielinski C. BRCA1-related breast cancer in Austrian breast and ovarian cancer families: specific BRCA1 mutations and pathological characteristics. Int J Cancer. 1998 Jul 29;77(3):354-60. Impact: 4.375

41. Huber S, Helbich TH, Kettenbach J, Dock W, Zuna I, Delorme S.

Effects of a microbubble contrast agent on breast tumors: computer-assisted quantitative assessment with color Doppler US-early experience. Radiology. 1998 Aug;208(2):485-9. Impact: 4.753

42. Wunderbaldinger P, Helbich TH, Youssefzadeh-Dorffner S, Partik B, Turetschek K,

Wolf G. Ultrasound-controlled stereotactic breast biopsy: description and initial clinical results of a new breast biopsy device. Wien Med Wochenschr. 1998;148(14):325-30. Impact: 0.0

43. Sedivy R, Partik B, Helbich TH, Breitenecker G, Wolf G.

Stereotactic breast biopsy: comparison of vacuum punch biopsy versus high speed core biopsy. Wien Med Wochenschr. 1998;148(14):331-4. Impact: 0.0

44. Schick S, Steiner E, Gahleitner A, Böhm P, Helbich TH, Ba-Ssalamah A, Mostbeck

GH. Differentiation of benign and malignant tumors of the parotid gland: value of pulsed Doppler and color Doppler sonography. Eur Radiol. 1998;8(8):1462-7. Impact: 0.783

45. Zontsich T, Helbich TH, Wojnarovsky C, Eichler I, Herold CJ.

Pulmonary alveolar proteinosis in a child: HRCT findings before and after bronchoalveolar lavage. Eur Radiol. 1998;8(9):1680-2. Impact: 0.783

46. Helbich TH, Popow C, Dobner M, Wunderbaldinger P, Zekert M, Herold CJ.

New-born infants with severe hyaline membrane disease: radiological evaluation

Section X 12/31

during high frequency oscillatory versus conventional ventilation. Eur J Radiol. 1998 Oct;28(3):243-9. Impact: 0.537

47. Helbich TH, Rudas M, Böhm G, Huber S, Wagner T, Taucher S, Wolf G,

Mostbeck GH. Randomized in vitro and in vivo evaluation of different biopsy needles and devices for breast biopsy. Clin Radiol. 1999 Jan;54(1):56-62. Impact: 1.117

48. Helbich TH, Heinz-Peer G, Fleischmann D, Wojnarowski C,

Wunderbaldinger P, Huber S, Eichler I, Herold CJ. Evolution of CT findings in patients with cystic fibrosis. AJR Am J Roentgenol. 1999 Jul;173(1):81-8. Impact: 2.307

49. Helbich TH, Stadler A, Wolf G.

Staging of breast carcinoma. Value of diagnostic imaging. Radiologe. 1999 Jul;39(7):546-54. Impact: 0.621

50. Wunderbaldinger P, Schima W, Turetschek K, Helbich TH, Bankier AA, Herold CJ.

World Wide Web and Internet: applications for radiologists. Eur Radiol. 1999;9(6):1170-82. Impact: 0.897

51. Gossmann A, Okuhata Y, Shames DM, Helbich TH, Roberts TP, Wendland MF,

Huber S, Brasch RC. Prostate cancer tumor grade differentiation with dynamic contrast-enhanced MR imaging in the rat: comparison of macromolecular and small-molecular contrast media-preliminary experience. Radiology. 1999 Oct;213(1):265-72. Impact: 4.621

52. Helbich TH, Heinz-Peer G, Eichler I, Wunderbaldinger P, Götz M, Wojnarowski C,

Brasch RC, Herold CJ. Cystic fibrosis: CT assessment of lung involvement in children and adults. Radiology. 1999 Nov;213(2):537-44. Impact: 4.621

53. Wagner TM, Moslinger R, Langbauer G, Ahner R, Fleischmann E, Auterith A,

Friedmann A, Helbich TH, Zielinski C, Pittermann E, Seifert M, Oefner P. Attitude towards prophylactic surgery and effects of genetic counselling in families with BRCA mutations. Austrian Hereditary Breast and Ovarian Cancer Group. Br J Cancer. 2000 Apr;82(7):1249-53. Impact: 3.894

54. Kucera E, Helbich TH, Sliutz G, Joura EA.

The modern management of interstitial or intramural pregnancy. Is MRI and “alloyed” diagnostic gold standard or the real thing? Fertil Steril. 2000 May;73(5):1063-4. Impact: 3.483

Section X 13/31

55. Helbich TH, Gossman A, Mareski PA, Raduechel B, Roberts TP, Shames DM, Muehler M, Turetschek K, Brasch RC. A new polysaccharide macromolecular contrast agent for MR imaging: biodistribution and imaging characteristics. J Magn Reson Imaging. 2000 Jun;11(6):694-701. Impact: 1.302

56. Helbich TH.

Contrast-enhanced magnetic resonance imaging of the breast. Eur J Radiol. 2000 Jun;34(3):208-19. Impact: 0.822

57. Helbich TH.

Tumor diagnosis and contrast media. Eur J Radiol. 2000 Jun;34(3):147-226. Impact: 0.822

58. Kinkel K, Helbich TH, Esserman LJ, Barclay J, Schwerin EH, Sickles EA, Hylton NM.

Dynamic high-spatial-resolution MR imaging of suspicious breast lesions: diagnostic criteria and interobserver variability. AJR Am J Roentgenol. 2000 Jul;175(1):35-43. Impact: 1.863

59. Huber S, Medl M, Helbich TH, Taucher S, Wagner T, Rudas M, Zuna I, Delorme S.

Locally advanced breast carcinoma: computer assisted semiquantitative analysis of color Doppler ultrasonography in the evaluation of tumor response to neoadjuvant chemotherapy. J Ultrasound Med. 2000 Sep;19(9):601-7. Impact: 0.966

60. Kucera E, Helbich TH, Klem I, Schurz B, Sliutz G, Leodolter S, Joura EA.

Systemic methotrexate treatment of interstitial pregnancy: magnetic resonance imaging (MRI) as a valuable tool for monitoring treatment. Wien Klin Wochenschr. 2000 Sep 15;112(17):772-5. Impact: 0.774

61. Löwe C, Fuchsjaeger M, Helbich TH.

Einflussfaktoren auf die Qualitaet von Mammographien Wien Klin Wochenschr. 2000 Sep 15;112(17):41-5. Impact: 0.774

62. Gossmann A, Helbich TH, Mesiano S, Shames DM, Wendland MF, Roberts TP,

Ferrara N, Jaffe RB, Brasch RC. Magnetic resonance imaging in an experimental model of human ovarian cancer demonstrating altered microvascular permeability after inhibition of vascular endothelial growth factor. Am J Obstet Gynecol. 2000 Oct;183(4):956-63. Impact: 2.518

63. Helbich TH.

Women's imaging: a challenge for radiology in Austria Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2000 Oct;172(10):238. Impact: 1.005

Section X 14/31

64. Helbich TH, Roberts TP, Gossmann A, Wendland MF, Shames DM, Adachi M, Yang S, Huber S, Daldrup H, Brasch RC. Quantitative gadopentetate-enhanced MRI of breast tumors: testing of different analytic methods. Magn Reson Med. 2000 Dec;44(6):915-24. Impact: 3.121

65. Helbich TH.

Mehr ueber die Mamma mittels MRT. Krebs:Hilfe. 2000. Impact: 0.0

66. Helbich TH.

Role of imaging modalities in cystic fibrosis. Monatsschrift Kinderheilkunde. 2001;3:246-58. Impact: 0.206

67. Jackman RJ, Burbank F, Parker SH, Evans WP 3rd, Lechner MC, Richardson TR,

Smid AA, Borofsky HB, Lee CH, Goldstein HM, Schilling KJ, Wray AB, Brem RF, Helbich TH, Lehrer DE, Adler SJ. Stereotactic breast biopsy of nonpalpable lesions: determinants of ductal carcinoma in situ underestimation rates. Radiology. 2001 Feb;218(2):497-502. Impact: 4.759

68. Turetschek K, Huber S, Floyd E, Helbich TH, Roberts TP, hames DMTarlo KS,

Wendland MF, Brasch RC. MR imaging characterization of microvessels in experimental breast tumors by using a particulate contrast agent with histopathologic correlation. Radiology. 2001 Feb;218(2):562-9. Impact: 4.759

69. Funovics M, Schamp S, Helbich TH, Lackner B, Wunderbaldinger P, Fuchsjaeger M,

Lechner G, Wolf G. Evaluation of a computer-assisted diagnosis system in breast carcinoma. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2001 Mar;173(3):218-23. Impact: 1.454

70. Helbich TH.

Localization and biopsy of breast lesions by magnetic resonance imaging guidance. J Magn Reson Imaging. 2001 Jun;13(6):903-11. Impact: 2.410

71. Wunderbaldinger P, Helbich TH, Partik B, Turetschek K, Wolf G.

First experience with a new dedicated ultrasound system for computer-guided large-core breast biopsy. Eur Radiol. 2001;11(12):2460-4. Impact: 1.321

72. Turetschek K, Floyd E, Helbich TH, Roberts TP, Shames DM, Wendland MF, Carter

WO, Brasch RC. MRI assessment of microvascular characteristics in experimental breast tumors using a new blood pool contrast agent (MS-325) with correlations to

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histopathology. J Magn Reson Imaging. 2001 Sep;14(3):237-42. Impact: 2.410

73. Partik B, Mallek R, Rudas M, Pokieser P, Wunderbaldinger P, Helbich TH.

Malignant and benign diseases of the breast in 41 male patients: mammography, sonography and pathohistological correlations. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2001 Nov;173(11):1012-8. Impact: 1.454

74. Heinz-Peer G, Helbich TH.

Urological and nephrological emergency: value of diagnostic imaging. Wien Med Wochenschr. 2001;151(21-23):560-4. Impact: 0.0

75. Kaindl E, Umek W, Heinz-Peer G, Helbich TH.

Diagnostic imaging in gynecological emergencies. Wien Med Wochenschr. 2001;151(21-23):568-72. Impact: 0.0

76. Kainberger F, Schima W, Helbich TH, Lechner G.

Radiological management in emergency and trauma medicine. Wien Med Wochenschr. 2001;151(21-23):483-4. Impact: 0.0

77. Kainberger F, Helbich TH, Grampp S, Heinz-Peer G, Schima W, Lechner G.

”Women’s imaging”: an integral diagnostic concept. Wien Med Wochenschr. 2001;151(21-23):546-7. Impact: 0.0

78. Herneth AM, Pokieser P, Philipp MO, Bader TR, Helbich TH, Mallek R,

Mostbeck GH. Role of Doppler sonography in the evaluation of accessory spleens after splenectomy. J Ultrasound Med. 2001 Dec;20(12):1347-51. Impact: 1.258

79. Fuchsjaeger MH, Helbich TH.

Das duktale In-situ-Karzinom der Mamma: eine diagnostische Herausforderung. Wiener MedWochenschr, 2002;152:69-73. Impact: 0.0

80. Helbich TH, Fuchsjaeger TH.

Mammographisches Referenzzentrum im Verbund mit einem Brustzentrum. Wiener MedWochenschr, 2002;152:82-84. Impact: 0.0

81. Gossmann A, Helbich TH, Kuriyama N, Ostrowitzki S, Roberts TP, Shames DM, van

Bruggen N, Wendland MF, Israel MA, Brasch RC. Dynamic contrast-enhanced magnetic resonance imaging as a surrogate marker of tumor response to anti-angiogenic therapy in a xenograft model of glioblastoma multiforme. J Magn Reson Imaging. 2002 Mar;15(3):233-40. Impact: 2.479

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82. Helbich TH, Buchberger W, Rudas M; Austrian Breast Imaging Study Group (ABISG). Stereotactically and sonographically guided vacuum-assisted breast biopsy: a national consensus for Austria. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2002 Apr;174(4):517-22. Impact: 1.669

83. Helbich TH, Roberts TP, Rollins MD, Shames DM, Turetschek K, Hopf HW, Muehler

M, Hunt TK, Brasch RC. Noninvasive assessment of wound-healing angiogenesis with contrast-enhanced MRI. Acad Radiol. 2002 May;9 Suppl 1:S145-7. Impact: 1.459

84. Pfarl G, Helbich TH, Riedl CC, Rudas M, Wagner T, Memarsadeghi M, Lomoschitz F.

Stereotactic needle breast biopsy: Diagnostic reliability of various biopsy systems and needle sizes. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2002 May;174(5):614-9. Impact: 1.669

85. Turetschek K, Huber S, Helbich TH, Floyd E, Tarlo KS, Roberts TP, Shames DM,

Wendland MF, Brasch RC. Dynamic MRI enhanced with albumin-(Gd-DTPA)30 or ultrasmall superparamagnetic iron oxide particles (NC100150 injection) for the measurement of microvessel permeability in experimental breast tumors. Acad Radiol. 2002 May;9 Suppl 1:S112-4. Impact: 1.459

86. Hörmann M, Puig S, Prokesch SR, Partik B, Helbich TH.

MR imaging of the normal appendix in children. Eur Radiol. 2002 Sep;12(9):2313-6. Epub 2002 May 09. Impact: 1.370

87. Wunderbaldinger P, Wolf G, Turetschek K, Helbich TH.

Comparison of sitting versus prone position for stereotactic large-core breast biopsy in surgically proven lesions. AJR Am J Roentgenol. 2002 May;178(5):1221-5. Impact: 2.424

88. Roberts TP, Helbich TH, Ley S, Turetschek K, Wendland MF, Shames DM, Brasch

RC. Utility (or not) of Gd-DTPA-based dynamic MRI for breast cancer diagnosis and grading. Acad Radiol. 2002 May;9 Suppl 1:S261-5. Impact: 1.459

89. Partik B, Rand T, Pretterklieber ML, Voracek M, Hömann M, Helbich TH.

Patterns of gadopentetate-enhanced MR imaging of radiocarpal joints of healthy subjects. AJR Am J Roentgenol. 2002 Jul;179(1):193-7. Impact: 2.424

90. Csapo B, Széles J, Helbich TH, Klarhöfer M, Balassy C, Pammer J, Obermair A.

Histopathologic correlation of high-resolution magnetic resonance imaging of

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human cervical tissue samples at 3 tesla: validation of a technique. Invest Radiol. 2002 Jul;37(7):381-5. Impact: 2.670

91. Pfarl G, Helbich TH.

Breast Imaging Reporting and Data System (BI-RADS) – German version. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2002 Jul;174(7):921-6. Impact: 1.669

92. Krestan CR, Riedl C, Memarsadeghi M, Rudas M, Pfarl G, Helbich TH.

3D-power Doppler ultrasound of breast lesions with a microbubble contrast agent. Acad Radiol. 2002 Aug;9 Suppl 2:S384-5. Impact: 1.459

93. Brasch RC, Gossmann A, Helbich TH, Kuriyama N, Roberts TP, Shames DM, van

Bruggen N, Wendland MF, Israel MA. Can a small-molecular gadolinium contrast agent be applied successfully with dynamic MRI to quantitatively define brain tumor microvascular responses to angiogenesis inhibition? Acad Radiol. 2002 Aug;9 Suppl 2:S326-7. Impact: 1.459

94. Daldrup-Link HE, Kaiser A, Link TM, Settles M, Helbich TH, Werner M, Roberts TP,

Rummeny EJ. Comparison between gadopentetate and feruglose (Clariscan)-enhanced MR-mammography: preliminary clinical experience. Acad Radiol. 2002 Aug;9 Suppl 2:S343-7. Impact: 1.459

95. Partik BL, Stadler A, Schamp S, Koller A, Voracek M, Heinz-Peer G, Helbich TH.

3D versus 2D ultrasound: accuracy of volume measurement in human cadaver kidneys. Invest Radiol. 2002 Sep;37(9):489-95. Impact: 2.670

96. Riedl C, Helbich TH, Pfarl G, Memarsadeghi M, Wagner T, Rudas M, Fuchsjaeger M.

Comparison of wire versus carbon localization of non-palpable breast lesions. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2002 Sep;174(9):1126-31. Impact: 1.669

97. Ba-Ssalamah A, Schima W, Schmook MT, Linnau KF, Schibany N, Helbich TH,

Reimer P, Laengle F, Wrba F, Kurtaran A, Ryan M, Mann FA. Atypical focal nodular hyperplasia of the liver: imaging features of nonspecific and liver-specific MR contrast agents. AJR Am J Roentgenol. 2002 Dec;179(6):1447-56. Impact: 2.424

98. Pfarl G, Helbich TH, Riedl C, Wagner T, Gnant M, Rudas M, Liberman L.

Stereotactic 11-gauge vacuum-assisted breast biopsy: a validation study. AJR Am J Roentgenol. 2002 Dec;179(6):1503-7. Impact: 2.424

99. Fuchsjaeger MH, Helbich TH, Ringl H, Funovics MA, Rudas M, Riedl C, Pfarl G.

Electrical impedance scanning in the differentiation of suspicious breast lesions:

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comparison with mammography, ultrasound and histopathology. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2002 Dec;174(12):1522-9. Impact: 1.669

100. Bloch BN, Helbich TH, Heinz-Peer G.

Prostatic carcinoma: current status of diagnostic imaging. Wien Med Wochenschr. 2002;(113):89-91. Impact: 0.0

101. Hörmann M, Scharitzer M, Stadler A, Pokieser P, Puig S, Helbich TH.

Ultrasound of the appendix in children: is the child too obese? Eur Radiol. 2003 Jun;13(6):1428-31. Impact: 1.969

102. Wimmer-Puchinger B, Guld S, Helbich TH, Kubista E, Salzer H.

Der Kluegere sieht nach. Geburtshilfe und Frauenheilkunde. 2003,10:1073-6. Impact: 0.0

103. Partik BL, Leung AN, Mueller MR, Breitenseher M, Eckersberger F, Dekan G,

Helbich TH, Metz V. Using a dedicated lung-marker system for localization of pulmonary nodules before thoracoscopic surgery. AJR Am J Roentgenol. 2003 Mar;180(3):805-9. Impact: 2.474

104. Memarsadeghi M, Pfarl G, Riedl C, Wagner T, Rudas M, Helbich TH.

Value of 14-gauge ultrasound-guided large-core needle biopsy of breast lesions: own results in comparison with the literature. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2003 Mar;175(3):374-80. Impact: 1.786

105. Daldrup-Link HE, Rydland J, Helbich TH, Bjornerud A, Turetschek K, Kvistad KA,

Kaindl E, Link TM, Staudacher K, Shames D, Brasch RC, Haraldseth O, Rummeny EJ. Quantification of breast tumor microvascular permeability with feruglose-enhanced MR imaging: initial phase II multicenter trial. Radiology. 2003 Dec;229(3):885-92. Impact: 4.815

106. Fuchsjaeger M, Philipp MO, Löwe C, Helbich TH.

Bildgebende Diagnostik bei Galaktorrhoe Wien Klin Wochenschr. 2003 Nov;115(19-20):33-9. Impact: 0.774

107. Daldrup-Link HE, Kaiser A, Helbich TH, Werner M, Bjornerud A, Link

TM,Rummeny EJ. Macromolecular contrast medium (feruglose) versus small molecular contrast medium (gadopentetate) enhanced magnetic resonance imaging: differentiation of benign and malignant breast lesions. Acad Radiol. 2003 Nov;10(11):1237-46. Impact: 1.409

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108. Pfarl G, Helbich TH. Standardisierter mammographischer Befund. Gynaekologie & Geburtshilfe. 2003,1:16-7. Impact: 0.0

109. Bloch BN, Helbich TH.

Prostatakarzinom: Neues aus der Bildgebung Krebs:Hilfe. 2003;2:18. Impact: 0.0

110. Helbich TH, Pfarl G.

Biopsie von Brustlaesionen Krebs:Hilfe. 2003;4:16. Impact: 0.0

111. Lang EK, Thomas R, Davis R, Myers L, Sabel A, Macchia R, Gayle B, Watson R,

Cho T, Richter F, Lechner G, Marberger M, Helbich TH. Multiphasic helical computerized tomography for the assessment of microscopic hematuria: a prospective study. J Urol. 2004 Jan;171(1):237-43. Impact: 3.713

112. Helbich TH.

Leitlinien fuer die Diagnose und Therapie des Mamakarzinoms” Leitlinien fuer die Oesterreichische Gesellschaft der Gynaekologen, 2004. Impact: 0.0

113. Helbich TH.

MR-Tomographie fuer Hochrisikopatientinnen. Krebs:Hilfe. 2004;3:9. Impact: 0.0

114. Helbich TH.

Mammakarzinom. Oesterreichische Aerztezeitung, March 2004;5:26-35. Impact: 0.0

115. Helbich TH.

Computed Tomography Laser Mammography – CTLM. European Hospital, Vol 13, Issue 3/04. Impact: 0.0

116. Helbich TH, Matzek W, Fuchsjaeger M.

Stereotactic and ultrasound-guided breast biopsy. Eur Radiol. 2004 Mar;14(3):383-93. Impact: 2.364

117. Schueller G, Neumann K, Helbich TH, Riemer H, Backfrieder W, Sertl K, Pittner B,

Herold CJ. HRCT and bronchial asthma: visualization of the pathophysiologic changes of the pulmonary parenchyma after inhalation provocation. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2004 Mar;176(3):335-41. Impact: 1.767

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118. Graf O, Helbich TH, Fuchsjaeger M, Hopf G, Morgun M, Graf C, Mallek R. Ultrasound follow-up of palpable solid, probably benign breast lesions BI-RADS category III. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2004 Mar;176(9):1251-6. Impact: 1.767

119. Helbich TH, Fuchsjaeger M, Runge VM.

Special issue "recent advances in breast imaging". Invest Radiol. 2004 May;39(5):249. Impact: 2.320

120. Lomoschitz F, Helbich TH, Rudas M, Pfarl G, Linnau K, Stadler A, Jackman R.

Stereotactic 11-gauge vacuum-assisted breast biopsy: infkluence of number specimens on diagnostic accuracy. Radiology. 2004 Sep;232(3):897-903. Impact: 5.076

121. Schueller G, Neumann K, Helbich TH, Riemer H, Backfrieder W, Sertl K, Herold

CJ. Bronchial reactivity in hyperresponsive patients and healthy individuals: demonstration with high resolution computed tomography. Eur J Radiol. 2004 Nov;52(2):151-6. Impact: 1.745

122. Graf O, Helbich TH, Fuchsjaeger M, Hopf G, Morgun M, Graf C, Mallek R, Sickles

EA. Follow-up of palpable circumscribed noncalcified solid breast masses mammography and US: can biopbsy be averted. Radiology. 2004 Dec; 233(3):850-6. Impact: 5.076

123. Kettenbach J, Helbich TH, Huber S, Zuna I, Dock W.

Computer-assisted quantitative assessment of power Doppler US: effects of microbubble contrast agent in the differentiation of breast tumors. Eur J Radiol. 2005 Feb;53(2):238-44. Impact: 1.888

124. Helbich TH.

Qualitaetszertifikat Mammadiagnostik – Guetesiegel fuer Mammographie. AErzte Woche, Fokus Radiologie, Mai 2005. Impact: 0.0

125. Memarsadeghi M, Heinz-Peer G, Helbich TH, Schaefer-Prokop C, Kramer G,

Scharitzer M, Prokop M. Unenhanced multidetector row CT in patients suspected of having urinary stone disease: effect of section width on diagnosis. Radiology. 2005 May;235(2):530-6. Impact: 5.377

126. Helbich TH.

Breast Imaging Reporting and data system (BI-RADSTM) Lehr- und Lernzielkatalog der Medizinischen Universitaet Wien, May 2005. Impact: 0.0

Section X 21/31

127. Floery D, Helbich TH, Riedl CC, Jaromi S, Weber M, Leodolter S, Fuchsjaeger MH. Characterization of benign and malignant breast lesions with computed tomography laser mammography (CTLM): initial experience. Invest Radiol. 2005 Jun;40(6):328-35. Impact: 3.173

128. Riedl CC, Jaromi S, Foery D, Pfarl G, Fuchsjaeger MH, Helbich TH.

Potential of dose reduction after marker placement with full-field digital mammography. Invest Radiol. 2005 Jun;40(6):343-8. Impact: 3.173

129. Floery D, Helbich TH.

MR breast imaging guides interventional procedures. Diagnostic Imaging Supplement, Focus on ECR 2005 June/July 2005. Impact: 0.0

130. Fuchsjaeger MH, Floery D, Reiner CS, Rudas M, Riedl CC, Helbich TH.

The negative predictive value of electrical impedance scanning in BIRADS category IV breast lesions. Invest Radiol. 2005 Jul;40(7):478-85 Impact: 3.173

131. Riedl CC, Pfarl G, Memarsadeghi M, Wagner T, Fitzal F, Rudas M,

Helbich TH. Lesion Miss Rates and False-Negative Rates for 1115 Consecutive Cases of Stereotactically Guided Needle-localized Open Breast Biopsy with Long-term Follow-up. Radiology 2005 Dec; 237(3):847-53. Impact: 5.377

132. Helbich TH.

Qualitaetsmanagement in der Radiologie. Jatros Radiologie, Jahrgang 4, October 3/2005. Impact: 0.0

133. Schueller G, Kaindl E, Matzek W, Semturs F, Schueller-Weidekamm C, Helbich

TH. Image quality of a wet laser printer versus a paper printer for full-field digital mammograms. AJR 2006 Jan; 186(1):38-43 Impact: 2.117

134. Fitzal F, Sporn E, Draxler W, Mittelböck M, Taucher S, Rudas M, Riedl O, Helbich

TH., Jakesz R, Gnant M. Preoperative Core Needle Biopsy does not Increase Local Recurrence Rate in Breast Cancer Patients. Breast Cancer Research and Treatment 2006, May;97(1):9-15; 24 Impact: 3.310

135. Dimopoulos J, Scharf G, Berger D, Lang S, Goldner G, Helbich TH, Pötter R

Systematic evaluation of MRI findings in different stages of teatment of cervical cancer: potential of MRI on delineation of target, pathoanatomic structures, and organs at risk.

Section X 22/31

Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1380-8. Impact: 4.297

136. Helbich TH, Kubista E, Leodolter S, Luschin-Ebengreuth G, Marth C, Menzel C,

Mueller-Holzner D, Reiner-Concin A, Rudas M, Salzer H, Sedlmayer F, Sevelda P, Wagner T Leitlinien zum Mammakarzinom – Arbeitsgemeinschaft Gynaekologische Onkologie Oesterreichische Aerztezeitung, Mai 2006. Impact: 0.0

137. Graf O, Helbich TH, Hopf G, Graf C, Sickles E.

Probably benign breast masses at ultrasound: is follow up an acceptable alternative to biopsy? Radiology 2007 Jul;244(1):87-93. Impact: 5.251

138. Floery D, Helbich TH MRI-Guided percutaneous biopsy of breast lesions: materials, techniques, success rates, and management in patients with suspected radiologic-pathologic mismatch Magn Reson Imaging Clin N Am. 2006 Aug;14(3):411-25. Impact: 1.580

139. Memarsadeghi M, Riedl CC, Kaneider A, Galid A, Rudas M, Matzek W,

Helbich TH Axillary lymph node metastases in patients with breast carcinomas: assessment with nonenhanced versus uspio-enhanced MR imaging. Radiology 2006 Nov;241(2):367-77. Impact: 5.251

140. Schueller G, Kaindl E, Langenberger H, Stadler A, Schueller-Weidekamm C,

Semturs F, Helbich TH Validation of image quality in full-field digital mammography: Is the replacement of wet by dry laser printers justified? Eur J Radiol. 2007 May; 62(2):267-72. Impact: 1.915

141. Wallis M, Tarvidon A, Helbich TH, Schreer I

Guidelines from the European Society of Breast Imaging for diagnostic interventional breast procedures. Eur Radiol. 2007 Feb;17(2):581-8. Impact: 3.405

142. Bloch BN, Furman-Haran E, Helbich TH, Lenkinski RE, Degani H, Kratzik C,

Susani M, Haitel A, Jaromi S, Ngo L, Rofsky NM Accurate Determination of Extracapsular Extension in Prostate Cancer using High Spatial Resolution Dynamic Contrast Enhanced and T2-W Magnetic Resonance Imaging: Initial Results. Radiology. 2007 Oct; 245(1):176-85. Impact: 5.561

143. Helbich TH.

Mammographie-Screening. Gyn-Aktiv. 2/2007. Impact: 0.0

Section X 23/31

144. Horak F Jr, Moeller A, Singer F, Straub D, Höller B, Helbich TH, Schneider B,

Eichler I, Wildhaber JH, Hall GL. Longitudinal monitoring of pediatric cystic fibrosis lung disease using nitrite in exhaled breath condensate. Pediatr Pulmonol. 2007 Dec;42(12):1198-206. Impact: 1.076

145. Riedl CC, Ponhold L, Flöry D, Weber M, Kroiss R, Wagner T, Fuchsjaeger M,

Helbich TH. Magnetic resonance imaging of the breast improves detection of invasive cancer, preinvasive cancer, and premalignant lesions during surveillance of women at high risk for breast cancer. Clin Cancer Res. 2007 Oct 15;13(20):6144-52. Impact: 7.827

146. Benditte-Klepetko H, Leisser V, Paternostro-Sluga T, Rakos M, Trattnig S,

Helbich TH, Schemper M, Deutinger M. Hypertrophy of the breast: a problem of beauty or health? J Womens Health (Larchmt). 2007 Sep;16(7):1062-9. Impact: 1.522

147. Memarsadeghi M, Schaefer-Prokop C, Prokop M, Helbich TH, Seitz CC,

Noebauer-Huhmann IM, Heinz-Peer G. Unenhanced MDCT in patients with suspected urinary stone disease: do coronal reformations improve diagnostic performance? AJR Am J Roentgenol. 2007 Aug;189(2):W60-4. Impact: 2.470

148. Bloch BN, Lenkinski RE, Helbich TH, Ngo L, Oismueller R, Jaromi S, Kubin K,

Hawliczek R, Kaplan ID, Rofsky NM. Prostate postbrachytherapy seed distribution: comparison of high-resolution, contrast-enhanced, T1- and T2-weighted endorectal magnetic resonance imaging versus computed tomography: initial experience. Int J Radiat Oncol Biol Phys. 2007 Sep 1;69(1):70-8. Impact: 4.290

149. Gruber R, Bernt R, Helbich TH.

Cost-Effectiveness of Percutaneous Core Needle Breast Biopsy (CNBB) Versus Open Surgical Biopsy (OSB) of Nonpalpable Breast Lesions: Metaanalysis and Cost Evaluation for German-Speaking Countries. Rofo. 2008; 180(2):134-42. Impact: 1.639

150. Riedl Ch, Helbich TH.

MRT zeigt signifikante Vorteile gegenueber der Mammographie. Gyn-Aktiv. 2008/02, 12. Impact: 0.0

151. Schueller G, Jaromi S, Ponhold L, Fuchsjaeger M, Memarsadeghi M, Rudas M,

Weber M, Liberman L, Helbich TH. US-guided 14-gauge core-needle breast biopsy: results of a validation study in 1352 cases. Radiology. 2008 Aug:248(2):406-13.

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Impact: 5.996 152. Schueller G, Riedl CC, Mallek R, Eibenberger K, Langenberger H, Kaindl E,

Kulinna-Cosentini C, Rudas M, Helbich TH. Image Quality, lesion detection, and diagnostic efficacy in digital mammography: Full-field digital mammography versus computed radiography-based mammography using digital storage phosphor plates. Eur J Radiol. 2008 Sep; 67(3):487-96 Impact: 2.339

153. Schueller G, Schueller-Weidekamm C, Helbich TH.

Accuracy of ultrasound-guided, large-core needle breast biopsy. Eur Radiol. 2008 Sept;18(9):1761-73. Impact: 3.651

154. Pfarl G, Helbich TH.

Entscheidungsorientiertes Befundsystem fuer Mammographie, Ultraschall und MRT. Breast Imaging Reporting and Data System (BI-RADS). Gyn-Aktiv. 2008/06, 12. Impact: 0.0

155. Helbich TH, Gruber R.

Ultraschall in der Mammadiagnostik. Up-date zur Nomenklatur der zystischen Brustlaesionen. OERG-News. 04-2009. Impact: 0.0

156. Flöry D, Fuchsjaeger MW, Weisman CF, Helbich TH.

Advances in breast imaging: a dilemma or progress? Recent Results Cancer Res. 2009; 173:159-81 Impact: 1.43

157. Schueller G, Schueller-Weidekamm C, Pinker K, Memarsadeghi M, Weber M,

Helbich TH Comparison of 5-megapixel cathode ray tube monitors and 5-megapixel liquid crystal monitors for soft-copy reading in full-field digital mammography. Eur J Radiol. 2010 Oct; 76(1):68-72. Impact: 2.645

158. Dimopoulos JC, Schirl G, Baldinger A, Helbich TH, Poetter R.

MRI assessment of cervical cancer for adaptive radiotherapy. Strahlenther Onkol. 2009 May;185(5):282-7. Impact: 3.776

159. Reiner CS, Helbich TH, Rudas M, Ponhold L, Riedl CC, Kropf N, Fuchsjaeger MH.

Can galactography-guided stereotactic, 11-gauge, vacuum-assisted breast biopsy of intraductal lesions serve as an alternative to surgical biopsy? Eur Radiol. 2009 Dec; 19(12):2878-85. Impact: 3.589

160. Bogner W, Gruber S, Pinker K, Grabner G, Stadlbauer A, Weber M, Moser E,

Helbich TH, Trattnig S.

Section X 25/31

Diffusion-weighted MR for Differentiation of Breast Lesions at 3.0 T: How Does Selection of Diffusion Protocols Affect Diagnosis? Radiology 2009 Nov; 253(2):341-51. Impact: 6.669

161. Pinker K, Grabner G, Bogner W, Gruber S, Szomolanyi P, Trattnig S, Heinz-Peer

G, Weber M, Fitzal F, Pluschnig U, Rudas M, Helbich TH. A combined high temporal and high spatial resolution 3 Tesla MR imaging protocol for the assessment of breast lesions: initial results. Invest Radiol. 2009 Sep; 44(9):553-8. Impact: 4.850

162. Wimmer-Puchinger B, Eger K, Helbich TH. Organized, quality-assured early detection of breast cancer: Challenges and success of the Vienna mammography pilot project, “I look after myself“ (Organisierte, qualitaetsgesicherte Brustkrebstfrueherkennung: Herausforderungen und Erfolge des Wiener mammographiemodellprojektes “ich schau auf mich”. Breast Care 2009; 4(5):342-343 Impact: 0.0

163. Sadaf A, Crystal P, Scaranelo A, Helbich TH.

Performance of computer-aided detection applied to full-field digital mammography in detection of breast cancer. Eur J Radiol. 2011 Mar; 77(3):457. Impact: 2.645

164. Pinker K, Stadlbauer A, Bogner W, Gruber S, Helbich TH. Molecular imaging of cancer: MR spectroscopy and beyond. Eur J Radiol. 2010 May; (Epub ahead of print). Impact: 2.941

165. Sardanelli F, Boetes C, Borisch B, Decker T, Federico M, Gilbert FJ, Helbich TH,

Heywang-Köbrunner SH, Kaiser WA, Kerin MJ, Mansel RE, Marotti L, Martincich L, Mauriac L, Meijers-Heijboer H, Orecchia R, Panizza P, Ponti A, Purushotham AD, Regitnig P, Del Turco MR, Thibault F, Wilson R. Magnetic resonance imaging of the breast: recommendations from the EUSOMA working group. Eur J Cancer. 2010 May;46(8):1296-316. Impact: 4.121

166. Scaranelo AM, Crystal P, Bukhanov K, Helbich TH.

Sensitivity of a direct computer-aided detection system in full-field digital mammography for detection of microcalcifications not associated with mass or architectural distortion. Can. Assoc. Radiol J. 2010 Jun;61(3):162-9 Impact: 0.400

167. Gruber R, Walter E, Helbich TH.

Cost comparison between ultrasound-guided 14g large core breast biopsy and open surgical biopsy: an analysis for Austria. Eur J Radiol 2010 Jun; 74(3):519-524 Impact: 2.941

168. Pinker K, Karanikas G, Helbich TH.

Funktionelle und molekulare Bildgebung bei Brusttumoren.

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OERG-News 2010 Oktober Impact: 0.0

169. Pinker K, Brader P, Karanikas G, El-Rabadi K, Bogner W, Gruber S, Reisegger M,

Helbich TH. Funktionelle und molekulare Bildgebung bei Brusttumoren. Der Radiologe, 2010 Nov; 50(11):1030-8 Impact: 0.523

170. Gruber R, Riedl CC, Reisegger M, Pinker K, Sturm E, Semturs F, Helbich TH.

Perspektiven der Digitalen Mammographie-Plattform. Der Radiologe, 2010 Nov; 50 (11):999-1007 Impact: 0.523

171. Helbich TH, Reiser M, Schlossbauer T, Imhof H.

Neue Entwicklung in der Brustdiagnostik. Der Radiologie, 2010 Nov; 50(11):954 Impact: 0.523

172. Semturs F, Sturm E, Gruber R, Helbich TH.

Physikalische Aspekte der verschiedenen Tomosynthese-Systeme. Der Radiologe, 2010 Nov; 50 (11):982-90 Impact: 0.523

173. Riedl C, Ponhold L, Gruber R, Pinker K, Helbich TH.

Neues zum Hochrisikomammascreening. Der Radiologe, 2010 Nov; 50 (11):955-6, 958-63 Impact: 0.523

174. Reisegger M, Schueller G, Gruber R, Pinker K, Riedl C, Helbich TH. Bildgebung molekularer Strukturen der Brust mit neuen Sonographietechniken. Der Radiologe, 2010 Nov; 50 (11):1014-21 Impact: 0.523

175. Pinker K, Brader P, Karanikas G, El-Rabadi K, Bogner W, Gruber S, Reisegger M, Trattnig S, Helbich TH. Functional and molecular imaging of breast tumors. Der Radiologe, 2010 Nov; 50(11):1030-8 Impact: 0.523

176. Riedl C, Helbich TH. Neue Richtlinien zum Hochrisiko-Mammascreening. Gyn-Aktiv 4/2010 Impact: 0.0

177. Boetes C, Helbich TH, Heywang-Köbrunner S, Ikeda D, Morris E, Sardanelli F. Breast Magnetic Resonance Imaging Breast Care 2010;5:425-429 Impact: 0.36

178. Riedl C, Helbich TH. Neue Richtlinien zum Hochrisiko-Mammascreening. Universum Innere Medizin 10/10 Impact: 0.0

Section X 27/31

179. Gruber R, Walter E, Helbich TH. Impact of stereotactic 11-g vacuum-assisted breast biopsy on cost of diagnosis in Austria. Eur J Radiol. 2011 Jan;77(1):131-6 Impact: 2.94

180. Kundu A, Peterlik H, Krssak M, Bytzek A, Pashkunova-Martic I, Arion V, Helbich

TH, Keppler B. Strategies for the covalent conjugation of a bifunctional chelating agent to albumin: Sythesis and characterization of potential MRI contrast agents. J Inorg Biochem. 2011 Feb; 105(2):250-5 Impact: 3.386

181. Crystal P, Sadaf A, Bukhanov K, McCready D, O’Malley F, Helbich TH. High-risk lesions diagnosed at MRI-guided vacuum-assisted breast biopsy: can underestimation be predicted? Eur. Radiology, 2011 Mar;21(3):582-9 Impact: 3.389

182. Pinker K, Bogner W, Gruber S, Brader P, Trattnig S, Karanikas G, Helbich TH. Molecular Imaging in Breast Cancer – Potential Future Aspects. Breast Care 2011;6:110-119 Impact: 0.36

183. Fueger BJ, Helbich TH, Schernthaner M, Zbyn S, Linhart HG, Stiglbauer A, Doan A, Pinker K, Geinz G, Padhani AR, Brader P. Diagnose importance of multiparametric magnetic resonance tomography for prostate cancer. Radiologe 2011 Nov; 51(11):947-54 Impact: 0.483

184. Schernthaner M, Helbich TH, Fueger BJ, Margreiter M, Memarsadeghi M, Stiglbauer A, Linhart HG, Doan A, Pinker K, Brader P. Magnetic resonance tomography-guided interventional procedure for diagnosis of prostate cancer. Radiologe 2011 Nov; 51(11):962-8 Impact: 0.483

185. Helbich TH, Reiser M, Herold CJ, Delorme S. What is new in prostate imaging? Radiologe 2011 Nov; 51(11):921 Impact: 0.483

186. Gruber S, Debski BK, Pinker K, Chmelik M, Grabner G, Helbich TH, Trattnig S, Bogner W. Three dimensional proton magnetic resonance spectroscopic imaging (3D-MRSI) for differentation of benign and malignant breast lesions at 3 Tesla. Radiology 2011 Dec; 261(3):752-61 Impact: 6.06

187. Pinker-Domenig K, Bogner W, Gruber S, Bickel H, Duffy S, Schernthaner M, Dubsky P, Pluschnig U, Rudas M, Trattnig S, Helbich TH. High resolution MRI of the breast at 3 T: which BI-RADS® descriptors are most strongly associated with the diagnosis of breast cancer? Eur Radiol. 2012 Feb; 22(2):322-30

Section X 28/31

Impact: 3.589

188. Sardanelli F, Helbich TH. Mammography: EUSOBI recommendations for women’s information. Insights Imaging 2012 Feb; 3(1):7-10 Impact: 0.0

189. Pinker K, Stadlbauer A, Bogner W, Gruber S, Helbich TH. Molecular imaging of cancer: MR spectroscopy and beyond. Eur J Radiol. 2012 Mar; 81(3):566-77 Impact : 2.94

190. Singer CF, Tea MK, Pristauz G, Hubalek M, Rappaport C, Riedl C, Helbich TH. Guideline for the prevention and early detection of breast and ovarian cancer in high risk patients, particularly in women from HBOC (hereditary breast and ovarian cancer) families. Wien Klin Wochenschr 2012 May; 124(9-10):334-9 Impact: 0.813

191. Gruber R, Jaromi S, Rudas M, Pfarl G, Riedl CC, Flösy D, Graf O, Sickles EA,

Helbich TH. Histologic work-up of non-palpable breast lesions classified as probably benign at initial mammography and/or ultrasound (BI-RADS category 3). Eur J Radiol, in press 2012 Impact: 2.94

192. Bogner W, Pinker K, Bickel H, Chmelik M, Weber M, Helbich TH, Trattnig S, Gruber S. Readout-Segmented Echo-planar Imaging Improves the Diagnostic Performance of Diffusion-weighted MR Imaging Breast Examinations at 3.0 T. Radiology 2012 April; 263(1):64-76 Impact: 6.06

193. Ponhold L, Bickel H, Pinker K, Helbich TH. Mammography screening and follow-up of breast cancer. Emirates Journal of Medical Sciences in press 2012 Impact: 0.0

194. Fruehwald-Pallamar J, Jantsch M, Pinker K, Hofmeister R, Semturs F, Piegler K, Staribacher D, Weber M, Helbich TH. Teleradiology with uncompressed digital mammograms: clinical assessment. Eur J Radiol, in press 2012 Impact: 2.94

195. Helbich TH. Brustkrebs: Mein Krebs ist nicht dein Krebs – Personalisierte Therapie und individuelle Betreuung besonders wichtig. Jatros 2012/4; 30 Impact: 0

196. Magometschnigg HF, Helbich TH, Brader P, Abeyakoon O, Baltzer P, Füger B, Wengert G, Polanec S, Bickel H, Pinker K. Molecular Imaging fort he Characterization of Breast Tumors. Expert Review for Anticancer Therapy, 2013, in review Impact: 2.066

Section X 29/31

197. Pinker K, Bickel H, Helbich TH, Gruber S, Dubsky P, Pluschnig U, Rudas M, Bao-

Horvath Z, Weber M, Trattnig S, Bogner W. Combined contrast-enhanced magnetic resonance and diffusion-weighted imaging reading adapted tot he „Breast Imaging Reporting and Data System“ for multiparametric 3-T imaging of breast leasons. Eur Radiol 2013 Jul;23(7):1791-802 Impact: 3.589

198. Gartlehner G, Thaler K, Chapman A, Kaminski-Hartenthaler A, Berzaczy D, Van Noord MG, Helbich TH. Mammography in combination with breast ultrasonography versus mammography for breast cancer screening in women at average risk. Cochrane Database Syst Rev. 2013 Apr 30;4 Impact: 5.703

199. Gartlehner G, Thaler KJ, Chapman A, Kaminski A, Berzaczy D, Van Noord MG, Helbich TH. Adjunct ultrasonography for breast cancer screening in women at average risk: a systematic review. Int J Evid Based Healthc. 2013 Jun;11(2):87-93 Impact: ??

200. Polanec SH, Helbich TH, Margreiter M, Klingler HC, Kubin K, Susani M, Pinker-Domenig K, Brader P. Magnetic Resonance Imaging-Guided Prostate Biopsy: Institutional Analysis and Systematic Review. RöFo, 2014 Feb. Impact: 1.97

201. Pinker-Domenig K, Bogner W, Baltzer P, Trattnig S, Gruber S, Abeyakoon O, Bernnathova M, Zaric O, Dubsky P, Bago-Horvath Z, Weber M, Leithner D, Helbich TH. Clinical Application of Bilateral High Temporal and Spatial Resolution Dynamic Contrast-Enhanced MR Imaging of the Breast at 7T. European Radiology 2014;24(4):913-20 Impact: 3.589

202. Polanec SH, Brader P, Pinker-Domenig K, Helbich TH. Die Wertigkeit des (multiparametrischen) MRT in der diagnose und im Staging. SPECTRUM Urologie 2013; 20-21, 2/2012 Impact: 0.0

203. Spick C, Pinker-Domenig K, Rudas M, Helbich TH, Baltzer PA. MRI-only lesions: application of diffusion-weighted imaging obviates unnecessary MR-guided breast biopsies. Eur Radiol 2014 Jun;24(6):1204 Impact: 3.589

204. Pinker K, Bogner W, Baltzer P, Gruber S, Bickel H, Brueck B, Trattnig S, Weber M, Dubsky P, Bago-Horvath Z, Bartsch R, Helbich TH. Improved Diagnostic Accuracy with Multiparametric Magnetic Resonance Imaging of the Breast Using Dynamic Contrast-Enhanced Magnitic Resonance Imaging Diffusion-weighted Imaging and 3-dimensional Proton Magnetic Resonance Spectroscopic Imaging.

Section X 30/31

Invest Radiol 2014 Jun;49(6):421 Impact:4.850

205. Pinker K, Helbich TH, Magometschnigg H, Fueger B, Baltzer P. Molecular breast imaging: an update Radiologe 2014;54(3):241-53 Impact: 0.483

206. Spick C, Szolar DH, Baltzer PA, Tillich M, Reittner P, Preidler KW, Pinker-Domenig K, Helbich TH. Rate of malignancy in MRI-detected probably benign (BI-RADS 3) lesions. AJR Am J Roentgenol 2014;202(3):684-9

Impact: 2.470

207. Clauser P, Pinker K, Helbich TH, Kapetas P, Bernathova M, Baltzer P. Fat saturation in dynamic breast MRI at 3 Tesla: is the Dixon technique superior to spectral fat saturation? A visual grading characteristics study. Eur Radiol 2014 Sep;24(9):2213-9 Impact: 3.589

208. Pinker K, Bogner W, Baltzer P, Karanikas G, Magometschnigg H, Brader P, Gruber S, Bickel H, Dubsky P, Bago-Horvath Z, Bartsch R, Weger M, Trattnig S, Helbich TH. Improved Differentiation of Benign and malignant Breast Tumors with Multiparametric 18Fluorodeoxyglucose Positron Emission Tomoraphy Magnetic Resonance Imaging: A Feasibility Study. Clin Cancer Res. 2014 Jul 1;20(13):3540-0 Impact: 7.827

209. Zbyn S, Krssak M, Memarsadeghi M, Gholami B, Haitel A, Weber M, Helbich TH. Trattnig S, Moser E, Gruber S. Technical Note: Evaluation of the Uncertainties in (Choline+Creatine)/Citrate Ratios Measured by Proton MR Spectroscopic Imaging in Patients Suspicious for Prostate Cancer. Röfo 2014 Ju; 186(7):698-702 Impact: 0.0

210. Lindenblatt N, El-Rabadi K, Helbich TH, Czembirek H, Deutinger M, Benditte-Klepetko H. Correlation between MRI results and intraoperative findings in patients with silicone breast implants. Int J Womens Health 2014 Jul 30;6:703-9 Impact: 0.0

211. Bogner W, Pinker K, Zaric O, Baltzer P, Minarikova L, Porter D, Bago-Horvath Z, Dubsky P, Helbich TH, Trattnig S, Gruber S. Bilateral Diffusion-weighted MR Imaging of Breast tumors with Submilimeter Resolution Using Readout-segmented Echo-planar Imaging at 7T. Radiology, 2014 Oct 23:122340 Impact: 6.06

212. Wengert GJ, Helbich TH, Vogl WD, Baltzer P, Langs G, Weber M, Bogner W, Gruber S, Trattnig S, Pinker K.

Section X 31/31

Introduction of an Automated User-Independent Quantitative Volumetric Magnetic Resonance Imaging Breast Density Measurement System Using the Dixon Sequence: Comparison With Mammographic Breast Density Assessment. Invest Radiol 2014 Oct 20 Impact: 4.85

213. Minarikova L, Gruber S, Bogner W, Pinker-Domenig K, Baltzer PA, Helbich TH, Trattnig S, Chmelik M. Dixon imaging-based partial volume correction improves quantification of choline detected by breast 3D-MRSI. Eur Radiol. 2014 Sept. 14 Impact: 3.589

214. Riedl C, Luft N, Bernhart C, Weber M, Bernathova M, Tea MKM, Rudas M, Singer C, Helbich TH. Triple Modality Screening Trial for Familial Breast Cancer Underlines the Importance of MRI and Questions the Role of Mammography and Ultrasound Regardless of Patient Mutation Status, Age, and Breast Density. JCO 2015 in press Impact: 19.06

215. Pinker K, Baltzer P, bogner W, Leithner D, Trattnig S, Zaric O, Dubsky P, Bago-Horvath Z, Rudas M, Gruber S, Weber M, Helbich TH. Implementation of Multiparametric Magnetic Resonance Imaging with High-Resolution Dynamic Contrast-Enhanced and diffusion-Weighted Magnetic Resonance Imaging at 7T Improves the Assessment of Breast Tumors: A Feasibility Study. Radiology 2015 in press Impact: 6.06