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Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M. Martín, Juan A. López, Raquel del Toro, Abel Sánchez-Aguilera, Lorena Arranz, Daniel Martín-Pérez, María Suárez-Lledó, Pedro Marín, Melissa Van Pel, Willem E. Fibbe, Jesús Vázquez, Stefan Scheding, Álvaro Urbano-Ispizúa, Simón Méndez-Ferrer Cell Reports Volume 3, Issue 5, Pages 1714-1724 (May 2013) DOI: 10.1016/j.celrep.2013.03.041 Copyright © 2013 The Authors Terms and Conditions

Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

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Page 1: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion 

Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M. Martín, Juan A. López, Raquel del Toro, Abel Sánchez-Aguilera, Lorena Arranz, Daniel Martín-Pérez, María Suárez-Lledó, Pedro Marín, Melissa Van Pel, Willem E. Fibbe, Jesús Vázquez, Stefan

Scheding, Álvaro Urbano-Ispizúa, Simón Méndez-Ferrer 

Cell Reports Volume 3, Issue 5, Pages 1714-1724 (May 2013)

DOI: 10.1016/j.celrep.2013.03.041

Copyright © 2013 The Authors Terms and Conditions

Page 2: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure 1

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 3: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure 2

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 4: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure 3

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 5: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure 4

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 6: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure 5

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 7: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure 6

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 8: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure S1

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 9: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure S2

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 10: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure S3

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 11: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure S4

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 12: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Figure S5

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions

Page 13: Self-Renewing Human Bone Marrow Mesenspheres Promote Hematopoietic Stem Cell Expansion Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M

Cell Reports 2013 3, 1714-1724DOI: (10.1016/j.celrep.2013.03.041) Copyright © 2013 The Authors Terms and Conditions