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E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Prioritization in EWAR
Methodology and Objectives
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Objectives of this lecture
• To describe the rationale of prioritizing
diseases for EWAR
• To define the methodology of prioritization
• To give an example of how prioritization is
carried out by WHO
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Prioritization
Rationale
Methodology
Prioritizationexercise
Determining priorities is a process of
assessing the relative importance
or value of alternative concerns.
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Rationale
Methodology
Prioritizationexercise
Human and financial resources are limited
Public health risks change
over time
International context
Too many
diseases
impair
surveillance
Prioritization
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Past experiences
Rationale
Methodology
Prioritizationexercise
•All countries should review their list of priority
diseases for surveillance periodically,
•Adaptation of the Delphi
method using workshops
and combinations of
e-mail/mail and workshop
sessions.
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Prioritization Criteria1. Present burden of disease2. Case fatality ratio3. Epidemic potential4. Potential threat/emergence/changing
pattern5. Health gain opportunity
through public health activities6. Social and economic impact7. International regulations or
programmes for surveillance and control
8. Public perception
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
WHO-proposed adaptation of the Delphi method
Rationale
Methodology
Prioritizationexercise
a Steering Committee formulates a list of diseases,
and criteria to include/exclude diseases for surveillance
a Steering Committee formulates a list of diseases,
and criteria to include/exclude diseases for surveillance
list is presented in a workshop to a group of
key people involved in surveillance
list is presented in a workshop to a group of
key people involved in surveillance
Each participant scores the diseases against
the criteria
Each participant scores the diseases against
the criteria
A summary of results is used to assess with statistical parameters
group agreement
A summary of results is used to assess with statistical parameters
group agreement
Results are discussed in plenary and, if the group feels that there is not enough agreement,
a second round of scoring can be undertaken
Results are discussed in plenary and, if the group feels that there is not enough agreement,
a second round of scoring can be undertaken
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Steps in the WHO Prioritization exercise
• 1st step: Appointment steering
committee
• 2nd step: Preparation
• 3rd step: Prioritization workshop
• 4th step: Postworkshop activities
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
1st step: Appointment steering committee
• Suggested 8-12 members.– ministry of health executive director– head of the surveillance
department/unit– heads of ministry of health or other
ministry departments involved in surveillance
– WHO representative and/or other international partners
– other relevant partners.
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Tasks
Agree on the objective and approach
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
2nd step: Preparation of prioritization exercise
• Agreeing the approach for the
prioritization exercise
• Planning the implementation
• Preparing the score sheet
• Preparing the disease fact sheet
• Inviting the participants
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Example of score sheet for participants
Rationale
Methodology
Prioritizationexercise
Disease Burden CFR Epidemic potential
Potential threat
Effect PH
activities
Social &
economic
IHRPublic
perception
Anthrax
Brucella
Cholera
Dengue
Diphtheria
JE
Hepatitis A
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Step 3: Prioritization workshop
• Introduction to the workshop• Discussion and clarification of the
criteria and the disease list• First round of scoring• Ranking and summary of the results
– For each disease, sum of raw scores (criteria)
– Each disease has a total score => ranking of disease
– To show degree of consensus: median score, inter-quartile range
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Example of scoring results
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Step 3: Prioritization workshop
• Feedback and discussion
• Second (and subsequent rounds) of scoring
• Presentation of results
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Step 4: Post-workshop activities
• Report writing
• Report on prioritization to health authorities
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Next steps after prioritization
• To strengthen surveillance and response
activities
FOCUS should be on TOP priority
diseases.
• No real cut-off point: number of diseases
under surveillance adapted to needs and
resources
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Next steps after prioritization
• Low scoring diseases
– consider discontinuing surveillance efforts
– review surveillance objectives
– look for alternative ways to get
information
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Next steps after prioritization
• Priority diseases not under surveillance
• Priority diseases already under
surveillance
• For each priority disease, revise
– Lab capacity
– Training needs
– Guidelines
Rationale
Methodology
Prioritizationexercise
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
References• WHO guidelines. Setting priorities in communicable disease surveillance
WHO/CDS/EPR/LYO/2006.3 • Fink A, Kosecoff J, Chassin M, Brook R. Consensus methods: characteristics,
and guidelines for use. American Journal of Public Health Medicine, 1984, 74:979–983.
• Carter A. Establishing goals, techniques and priorities for national communicable disease surveillance. Canadian Journal of Infectious Disease, 1991, 2:37–40.
• Doherty J. Establishing priorities for national communicable disease surveillance. Canadian Journal of Infectious Disease, 2000, 11:21–24.
• Horby P, Rushdy A, Graham C, O'Mahony M. PHLS overview of communicable diseases 1999. Communicable Disease and Public Health, 2001, 4:8–17.
• Hubert B, Haury B. Orientations pour la révision des modalités de surveillance des maladies transmissibles en France. Bulletin Epidémiologique Hebdomadaire, 1996,
• Rushdy A, O'Mahony M. PHLS overview of communicable diseases 1997: results of a priority setting exercise. Communicable Disease Report, 1998, 8:1–12.
• Valenciano M. Définition des priorités dans le domaine des zoonoses non alimentaires 2000-2001. Institut de Veille Sanitaire, 2002 (http://www.invs.sante.fr/publications/2002/def_priorite_zoonoses)
• Weinberg J, Grimaud O, Newton L. Establishing priorities for European collaboration in communicable disease surveillance. European Journal of Public Health, 1999, 9:236–240.
E P I D E M I C A L E R T A N D R E S P O N S E SEARO –CSR Early Warning and Surveillance System Module
Question Time
1. Why should the prioritization exercise be conducted?
2. Do you agree with the WHO approach to prioritization?