SEARCHING THE LITERATURE Jane W. Griffith, MSLS …wichita.kumc.edu/Documents/wichita/wcgme/Searching-the-Literature.pdfSEARCHING THE LITERATURE Jane W. Griffith, MSLS Biomedical Reference

SEARCHING THE LITERATURE

Jane W. Griffith, MSLS Biomedical Reference Librarian George J. Farha Medical Library

The University of Kansas School of Medicine-Wichita (316) 293-2629

[email protected]

WHAT YOU SHOULD KNOW AFTER THIS PRESENTATION:

Searching The Scientific Literature

1. What are the steps in planning your search?

2. What are the three methods in PubMed to search for a topic?

3. How do you place limits on a search in PubMed?

4. How do you retrieve your search history in PubMed?

5. What is the usefulness of

MDConsult

Cochrane Library

UpToDate

Clinicaltrials.gov

Grey Literature Collection

ISI Web of Knowledge

6. Who can help you with your literature searches?

Searching the Literature

Index

0:00 Introduction

8:33 Basic Search inPubMed

17:39 MeSH Search inPubMed

25:19 Clinical Trials.gov inPubMed

30:42 MDconsult

33:27 UpToDate

36:27 Google Scholar

38:00 Grey Literature

40:09 Web of Science

KU Medical School Home Page

http://wichita.kumc.edu

Farha Medical Library Home Page http://wichita.kumc.edu/library/

• Click Quick Links to display a list of frequently used information resources. L • Click Find a Book to use the online catalog or go to the E-journal page. • Click Subject Links to see evidence based medicine resources. • Click Publication Support to find Author Instructions for the journal where you

plan to submit your research article.

Click Library to see databases, full text journal links, and other information resources.

Searching the Literature page1

The Strategy: Planning Your Search

Define the information need and state it as a question or statement Stating your information need as a question or a statement helps you define it and understand the relationships between its component parts. Example: I want articles providing evidence of effectiveness of reducing house mites as a treatment for asthma in adults.

Break the question/ statement into its component concepts Identify the important concepts from the question. Example: 1) asthma, 2) treatment, 3) house mites 4) adults 5) evidence of effectiveness.

Identify synonyms for each concept

Consult the thesaurus for synonyms used in the database(s) which you plan to search. The Medline database contains Medical Subject Headings (MeSH). In PubMed, use the MeSH Database to use MeSH terms. Consider keywords, also, for concepts which are not found in the MeSH Database. Use the keywords in the PubMed’s Basic Search box at the top of the PubMed page.

Consider terms from the handout Search Terms for Retrieving Evidence Based Information.

Prioritize concepts Begin with the concept that is central to the question, then use the other concepts to narrow or limit the resulting retrieval. Example: Begin by looking up asthma, then narrow the search by looking for those records which also mention the therapy concept, then narrow by the house mites concept. Finally, limit retrieval to randomized controlled trial OR meta-analysis as a Publication Type (or other evidence based filter terms).

Use connecting terms to construct logical relationships between concepts

The basic connecting terms are AND, OR, and NOT. In PubMED, remember to capitalize all letters of the connecting terms.

Use AND when you want both terms to appear in the database records retrieved with your search. AND narrows the search.

For example, asthma AND mites will retrieve records (article information) with both concepts.

Use OR when you want any one of the terms to appear in the records. OR broadens a search. For example, “randomized controlled trial OR meta-analysis” will retrieve either type of study. Use NOT to retrieve articles which have one concept, but not the second.

Use the NOT connector with caution because it may eliminate some records which would be of value. For example, if you say NOT animal, you will probably eliminate some records which mention both human and animal.

Select the appropriate database(s) for the search

Select database(s) which are likely to contain information relating to your topic of interest. Example: If you have a psychiatric or psychological topic, you might consider running the search in both PubMed (including Medline) and PsycINFO (from the American Psychological Association).

Run the search, evaluate the retrieval, and modify the search as needed.


PubMed (Medline) http://www.ncbi.nlm.nih.gov/sites/entrez?dr=abstract&otool=kumclib

Connecting Terms 3 Methods to Search for a Topic (Capitalize ALL Letters)

1. Basic Search 2. MeSH Database AND 3. Clinical Queries (EBM)

OR

NOT

Basic Search #1

Click Limits to limit retrieval to English language, human, age, publication type, etc

MeSH Database #3

Clinical Queries (EBM) #3

MyNCBI

Advanced Search


Scientific Studies

Meta-Analysis/ Systematic Review

Randomized Controlled Trial

Cohort Study

Case-Control Study

Case Series

Case Report

Search Terms for Retrieving Evidence Based Information1

MeSH Terms2 Text Words2 Publication Types2

S T R E N G T H O F I N F E R E N C E


Therapy

Double-blind method Random allocation Placebos Treatment outcome Research design

Random* Randomized Double-blind Placebo Mask OR masked

Randomized controlled trial Multicenter study Clinical trial Meta-analysis

Diagnosis Sensitivity and specificity Predictive value of tests ROC curve False positive reactions False negative reactions

Sensitivity Specificity False reaction* Predictive value* ROC Likelihood ratio

Etiology/ Harm

Epidemiologic studies Case-control studies Retrospective studies Cohort studies Longitudinal studies Prospective studies Follow-up studies Cross-sectional studies Odds ratio Risk Causality Risk factors

Cohort Case control Risk Etiolog* OR aetiolog* Causation Causal Cause Random Randomized Randomised Randomly

Randomized controlled trial

Prognosis

Epidemiologic studies Cohort studies Longitudinal studies Follow-up studies Morbidity Mortality Incidence Prevalence Prognosis Disease progression Time factors

Prognosis OR prognoses Natural history Inception cohort Clinical course

Comparative and Clinical Studies

Comparative study

Clinical trial

Meta-Analysis

Metaanalysis Meta analysis Meta-analysis Overview

Meta-analysis

1Primary information source: McKibbon KA and Dilks CW, “Panning for Applied Clinical Research Gold,” Online 1993 Jul;17(4):105-108 2In PubMed, search for 1) MeSH terms with the MeSH Database, 2) for Text Words in the Basic Search Box, and 3) for Publication Types by clicking Limits, then selecting from Type of Article.

Clinical Trials.gov

http://clinicaltrials.gov/


This resource is accessible from any Internet connection without charge.

Provides information about federally and privately supported clinical research in human volunteers

Search Options • Search box • More options


MDConsult**

http://www.mdconsult.com

MDConsult offers a core clinical collection of full text books and journals. Also, it provides a search interface to PubMed (Medline) and other resources for clinicians.

** MDConsult is available to KU Medical School-Wichita affiliates on campus. Off campus access is available with VPN or with KUSM-W network logon.

Search for topic

Click tabs to learn which books and

journals are available in full text.


UpToDate**

http://www.uptodate.com

UpToDate is an evidence based, peer reviewed clinical information resource designed to get physicians concise, practical answers at the point of care. 7400 topic reviews in 13 medical specialties are written by 3800 physicians. The content goes through an extensive peer review process to ensure that the information and recommendations are accurate and reliable. It is fully referenced. Reviews are updated regularly. ** UpToDate is available to KU Medical School-Wichita affiliates on campus or off campus with VPN.

To begin, click Search


Grey Literature Collection

New York Academy of Medicine http://www.nyam.org/library/pages/grey_literature_report

The Grey Literature Report is a bimonthly publication of the New York Academy of Medicine Library which provides access to grey literature publications in public health. You may subscribe to receive the report or search the entire collection at once. It provides hyperlinks to the full text of the reports on the web. The service is free from any Internet connection. This resource provides access to many reports not indexed in PubMed, such as reports from the Rand Corporation, Kaiser Permanente, universities, and the World Health Organization.

Enter keywords here to search the entire Grey Literature Collection.

Use AND, OR, or NOT to separate individual terms when keyword searching

To search for a phrase, enclose the words in quotation marks: “communication barriers”


ISI Web of Knowledge Including Web of Science

Link from the Farha Medical Library Web Page Databases on the Web

Affiliates of the KU Medical School at Wichita may use this resource while on campus or off campus with VPN or network logon. Tutorial at: http://www.isinet.com/tutorials/webofscience/index.html

To look up a journal’s Impact Factor, select Additional Resources, then Journal Citation Reports

Select Cited Reference Search to learn which articles have cited your article.

Log Out when you are done


National Library of Medicine

http://www.nlm.nih.gov/

Click here for Health Services Research tools listed on next page.

Click here to see a list of resources available.


Health Services Research & Public Health Information Programs (National Library of Medicine)

http://www.nlm.nih.gov/hsrph.html

Search for datasets or instruments/ indices used in health services research, behavioral and social sciences and public health.

Search for (or browse) research projects in progress

Search PubMed for Healthy People 2010 topics

Search PubMed for a topic and limit by Health Services Research Category (Appropriateness Process Assessment, Outcomes Assessment, Costs, Economics, and Qualitative Research).


University of Kansas School of Medicine at Wichita George J. Farha Medical Library

1010 N. Kansas Wichita, KS 67214-3199

(316) 293-2629; Fax (316) 293-2608 Web Page: http://wichita.kumc.edu/library

The Farha Medical Library provides information, instructional resources and support services to KU School of Medicine students, residents, physicians, faculty, and staff. The library provides access to 13,000 e-journals, electronic books through MDConsult and AccessMedicine, plus a core collection of printed medical books, study guides, and journals. Bibliographic and full text information can be obtained from various online database systems. The computer lab with 13 computers provides access for affiliates of the KU School of Medicine to the Internet, e-mail, databases, statistical softwares, the Microsoft Office Suite, and EndNote bibliographic management software. Three study rooms on the lower level have computers with a networked printer. DATABASES WITH LINKS TO FULL TEXT BOOKS AND JOURNAL ARTICLES ON THE WEB • PubMed • MDConsult • UpToDate • International Pharmaceutical Abstracts (OVID) • PsycInfo (CSA) • Access Medicine • Access Surgery • Web of Science • KU Medical Libraries Catalog http://catalog.library.kumc.edu/ LIBRARY HOURS Monday – Friday 8:00 a.m.-5:00 p.m. REFERENCE HOURS Monday – Friday 8:00 a.m.-5:00 p.m. Professional staff members are available to assist with: Information resource consultation • Online database searches • Assistance with software applications in the computer lab (e.g., EndNote or

PowerPoint) • Informal training in database searching (e.g., PubMed) CIRCULATION KU School of Medicine faculty, residents, students, and staff have full check out privileges. INTERLIBRARY LOAN/ DOCUMENT DELIVERY • Books and journal articles not available in the Farha Library may be borrowed. • Library staff will provide copies of articles from our journals for faculty and

residents at $2.00 per article. EQUIPMENT/ FACILITIES • Computer lab: 13 computers with Internet connections, networked printers and 1 scanner • Wireless access • 3 study rooms (each with a computer and networked printer) • Photocopier – coin operated: 10 cents/page CONTACTS Jane Griffith, MSLS, Assistant Director Reference, Literature searches Patty Shay, Library Assistant Interlibrary Loan Susan Clark, Library Assistant Reference, Interlibrary Loan Angie Shepherd, Administrative Specialist Circulation Marianne Eyles, Administrative Assistant Circulation

Via Christi Regional Medical Center Via Christi Libraries


St. Francis Campus Library St. Joseph Campus Library 929 N. St. Francis 3600 E. Harry Wichita, KS 67214 Wichita, KS 67218 (316) 268-5979 (316) 689-5376 Fax (316) 268-8694 Fax (316)691-6721

Library Web Page: http://www.via-christi.org/rmclibrary

USER POLICY

FULL LIBRARY PRIVILEGES are extended to all employees, attending staff physicians, and residents on rotation at Via Christi Regional Medical Center. Limited privileges are available for medical students and other health care professionals in the community.

NURSING STUDENTS from affiliated undergraduate and graduate programs may utilize resources within the Library. They do not have regular library and interlibrary loan privileges.

ATTORNEYS must have permission from Via Christi’s legal counsel to use materials within the Library.

PATIENT/ FAMILY MEMBERS and other non-professional requests will be referred to the Marcus Health Center located at the St. Francis Campus. Designated computers with Internet access are also available at the Libraries on each campus. LIBRARY HOURS St. Francis Campus/St. Joseph Campus Monday - Friday, 8:00 AM - 4:30 PM

SERVICES Circulation

Books: Four weeks with renewals unless requested by another patron. Journals: Back issues – 1 week. Current journals are not checked out. Reference Medical bibliographic searching tools are web-based through Ebsco Publishing Services Inc. to provide access to MEDLINE, CINAHL, Cochrane Database of Systematic Reviews, et al. Other databases include UpToDate, ACP PIER, STAT!REF, Anatomy TV, and Micromedex. Residents on rotation at Via Christi may request a User ID and Password list for off campus access to various databases and online journal packages through the Library homepage (http://www.via-christi.org/rmclibrary) by filling out the “Request Access” inter-active form. Additional Information Interlibrary Loan:

Local interlibrary loans are provided without charge and are turned-around within 3-5 working days. Turn-around time can be as long as two weeks. Please specify if an article request is for urgent patient care. Out-of-town requests can normally be found for free. Patrons are responsible for out-of-town requests with charges.

Library Online Catalog: Includes holdings of both the St. Francis and St. Joseph Campus libraries. The web-based library catalog is available through links on the Library homepage listed above.

Photocopy Machines: All patrons are responsible for their own photocopying needs. Students are charged 10 cents per page. Staff is unable to photocopy articles for patrons.

Audio-Visual Equipment: Available for check-out, including laptops and computer projectors. Internet Terminals:

Available for patron use at no charge. However, printing of material not related to medical research will be charged at 10 cents per page.

Library Contacts: St. Francis Campus - 268-5979 St. Joseph Campus - 689-5376

Sue Fleming, Medical Librarian Cam Gentry, Medical Librarian Kristin Sen, Manager Cheri Sellers, Asst. Librarian


D. Cramer Reed Health Science Library Wesley Medical Center

550 N. Hillside Wichita, Ks 67214

(316) 962-2715

(316) 962-7215 (fax) [email protected]

The D. Cramer Reed Health Science Library is located on the third floor of Building 7 (Critical Care Building) of the medical center. The library is open to medical staff, residents, medical students, Wesley employees, and health science students. The library maintains a large collection of medical, nursing, and allied health monographs and journals. The library features the Ovid electronic system, which includes Medline, CINAHL, EMB Reviews, and many full text journals. LIBRARY HOURS Reed Library is open 9:00 a.m. to 4:30 p.m., Monday through Friday. The library is closed Saturday, Sunday, and major holidays. SERVICES CIRCULATION

Check out privileges are available to medical staff, residents, medical students, and Wesley employees. Books in the general collection circulate for two weeks, with two renewals. Journals, reference, and reserve materials do not circulate.

INTERLIBRARY LOAN Interlibrary loans are available to medical staff, residents, medical students, and Wesley employees. Many items may be obtained without cost.

OTHER SERVICES Reed Library has an online text catalog available at: http://maple.cybertoolsforlibraries.com/cgi-bin/CyberHTML?MCKBBNHO A public photocopier is available. CONTACTS Leslie James and Jane Tanner, Librarians
