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Scientific Programme| 3 November 2011 |

3 November 2011 (Thursday)

1:00 pm Registration

Exhibition Area Seminar Room 1-2

Poster Session - Psychosocial OncologyChairperson: Sunny KS Liu, Society for the Promotion of Hospice Care, HKAdjudicator: Afaf Girgis, University of New South Wales, Australia

Free Paper Session – BiomedicineChairperson: Maria L Lung, The University of Hong Kong, HK

Abstract no. Abstract no.

2:00 pm –2:05 pm

A73 A Pilot Study to Explore the Experiences of Applying Dignity Therapy on Chinese Palliative Patients in Hong KongNHY Ng

2:00 pm –2:10 pm

A69 Health-related Quality of Life in Childhood Cancer SurvivorsDKL Cheuk, AKS Chiang, SY Ha and GCF Chan

2:05 pm –2:10 pm

A74 Audit of End of Life Care Checklist for Dying Patients in the Palliative Care UnitPT Lam, HY Ng, WY Cheung, KK Cheung and MW Leung

2:10 pm –2:15 pm

A75 Audit on Dyspnoea Control in a Palliative Care UnitSS Kwan, PT Lam and D Chao

2:10 pm –2:20 pm

A48 Co-localization of Migrationassociated Proteins in Proliferative Mitochondria of Lung Cancer A549 Cells upon Epithelial-mesenchymal TransitionZ Chen, T Wang, X Yin, G Yu, Y Chen, R Le, J Guo and QY He

2:15 pm –2:20 pm

A80 Getting Inside their Brains: Exploring the Psycho-social Needs and Employment-related Concerns of Chinese Childhood Brain Tumor SurvivorsPOK Ng, PPY Leung and CLW Chan

2:20 pm –2:25 pm

A84 The Grief and Guilt Experience among Bereaved College StudentsJ Li, C Chan and A Chow

2:20 pm –2:30 pm

A4 Bayesian Adaptive Designs for Early-Phase Oncology TrialsG Yin

2:25 pm –2:30 pm

A85 To Eat or Not to Eat? A Preliminary Study on the Dietary Restrictions of Chinese Breast Cancer Patients under Adjuvant TreatmentPHY Lo, TOT Sham, RTH Ho and IKM Cheung

2:30 pm –2:40 pm

A50 A Study of the Role of Aldehyde Dehydrogenase (ALDH) in Acute Myeloid Leukemia (AML)MY Ho, HC Han, HCH Chow, TK Fung andAYH Leung

2:40 pm –2:50 pm

A49 Who will Benefit from Prophylactic Cranial Irradiation? A Case Series of 289 Limited Stage Small Cell Lung CancerTHP Tai, M Jancewicz, A Assouline, C Krzisch, K Joseph and E Yu

3:00 pm Coffee Break

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Scientific Programme 3 November 2011 Continued

3 November 2011 (Thursday)

Seminar Room 3 Seminar Room 1-2

Young Investigator Award – Psychosocial OncologyChairperson: Sunny KS Liu, Society for the Promotion of Hospice Care, HKAdjudicators: Afaf Girgis, University of New South Wales, AustraliaEsther Mok, The Hong Kong Polytechnic University, HK

Young Investigator Award – BiomedicineChairperson: Maria L Lung, The University of Hong Kong, HKAdjudicators: Yuzhuo Wang, University of British Columbia, CanadaWai-Keung Leung, The University of Hong Kong, HK

Abstract no. Abstract no.

3:30 pm –3:40 pm

A82 Living and Dying with Dignity: An Action Plan for Palliative Long-Term-Care in Hong KongAHY Ho and CLW Chan

A54 Targeting JAK/STAT Pathway in Acute Myeloid Leukemia (AML) – A Potential Therapeutic Strategy and its Link to WNT PathwayHHC Han, CH Man, TK Fung, ACH Ma, HCH Chowand AYH Leung

3:40 pm –3:50 pm

A76 Change Patterns in Supportive Care Needs among Women Diagnosed with AdvancedBreast CancerA Au, WWT Lam, J Tsang, TK Yau, I Soong, W Yeo,J Suen, WM Ho, KY Wong, A Kwong, D Suen, WK Sze, A Ng, A Girgis and R Fielding

A38 Combined GEP Targeted Therapy and Chemotherapy Eradicated Human HCC in Orthotopic Mouse ModelNCL Wong, PFY Cheung and ST Cheun

3:50 pm –4:00 pm

A79 Eat, Taste, Love: Meaning Construction of Patients at their End-of-LifeMYJ Tam, POK Ng, PPY Leung, RSK Lo and CLW Chan

A90 Prolyl 4-hydroxylase, Beta Polypeptide (P4HB): A Potential Target for Overcoming Temozolomide Resistance in Human Malignant GliomaS Sun, JKS Pu and GKK Leung

4:00 pm –4:10 pm

A78 Dignity Amidst the Liminal Space betweenLiving and Dying: Suffering and Healing ofChinese Terminal Cancer PatientsAHY Ho and CLW Chan

A27 Downregulation of miR-199b-5p is Associated with Chemoresistance via Jagged1 in Human Ovarian CancerMX Liu, DW Chan and HYS Ngan

4:10 pm –4:20 pm

A77 Connectedness and Harmonization: Spirituality among End-Stage Cancer PatientsCHC Fong, PPY Leung, POK Ng, PMY Tse, J Leung, CLW Chan and RSK Lo

A57 Cyclin D1 Overexpression Supports Stable EBV Infection in Nasopharyngeal Epithelial CellsCM Tsang and SW Tsao

4:20 pm –4:30 pm

A81 Integrating a Body Mind Wellness Methodology Using White Light Visualization Technique in Adult Clients with Cancer in a Tertiary Care Cancer Center: A Pilot StudyP Gupta, S Paliwal, TP Thankachan and A Narayan

A51 Effect of Sorafenib Treatment inFLT3-ITD+ Acute Myeloid Leukemia: Mechanism of Non-responsive and Emergence of Novel ClonesCH Man, TK Fung, C Ho,HHC Han, HCH Chow, ACH Ma, WWL Choi, YL Kwong and AYH Leung

4:30 pm –4:40 pm

A83 Psychological Coping Outcomes of Chinese Breast Cancer Survivors: The Role of Trait Resilience and Cognitive AppraisalsAHY Wan, PPY Leung, RKY Liu and P Zhou

A42 Overexpression of miR106b Promotes Metastasis in Hepatocellular Carcinoma by Activating Epithelialmesenchymal Transition ProcessWL Yau, RWC Pang, TKW Lee, CSC Lam, JYH Wo, L Ng, JYK Chan, AKM Chow, KTP Ng, K Man and RTP Poon

4:40 pm –4:50 pm

A43 Potential DNA Double Strand Breaks (DSBs)Repair Mechanism Mediated Chemo-resistance in Hepatocellular CarcinomaST Yang and XQ Wang

4:50 pm –5:00 pm

A65 Semi-Automatic Lesion Tracking and Measuring Tool for Diagnosing and Evaluating Treatment Response of NPC from PET/CT ImagesRW Chan, T Chan and EX Wu

5:00 pm –5:10 pm

A20 A Novel Pathogenicity of Colorectal Cancer in Young Patients with MSI-H and Loss of MLH1 ExpressionC Li, ST Yuen, AKW Chan, WWY Tsui, ASY Chan, SY Leung and TL Chan

Deliberation by adjudicators on YIA. Deliberation by adjudicators on YIA.

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Scientific Programme| 4 November 2011 |

4 November 2011 (Friday)

Lecture Theatre 3

9:00 am Opening Ceremony

Welcoming address by Professor George SW Tsao, Director, Centre for Cancer Research, Li Ka Shing Faculty of Medicine, HKU

Presentation of Young Investigator Award and Poster Prize by Dr Wai-Lun Cheung, Director, Cluster Services, Hospital Authority and Professor Sum-Ping Lee, Dean, Li Ka Shing Faculty of Medicine, HKU

Officiating address by Dr Wai-Lun Cheung, Director, Cluster Services, Hospital Authority

Presentation of Souvenir to Guest-of-Honour by Professor Suet-Yi Leung, Deputy Director, Centre for Cancer Research, Li Ka Shing Faculty of Medicine, HKU

Group Photo and Lion Dance Performance

9:30 am HKICC LectureChairperson: George SW Tsao, The University of Hong Kong, HK

Integration of Traditional Chinese Medicine into Mainstream Cancer Treatment: Steps Needed For GlobalizationYung-Chi Cheng, Yale University School of Medicine, USA

10:30 am Coffee Break

Lecture Theatre 3 Lecture Theatre 4

11:00 am -12:30 pm

State-of-the-Art LectureBattling Cancer at All FrontsChairperson: James CS Chim, The University of Hong Kong, HK

State-of-the-Art LecturePsychosocial Oncology (HKCF)Chairperson: Katherine Chow, CancerLink Support Centre (Central), Hong Kong Cancer Fund, HK

11:00 am

Optimizing Molecular Targeted Therapy for Lung CancerTony SK Mok, The Chinese University of Hong Kong, HK

11:00 am

Is Anyone Caring for the Caregivers of Cancer Survivors?Afaf Girgis, University of New South Wales, Australia

State-of-the-Art LectureBattling Cancer at All FrontsChairperson: Paul BS Lai, The Chinese University of Hong Kong, HK

State-of-the-Art LecturePsychosocial Oncology (HKCF)Chairperson: Katherine Chow, CancerLink Support Centre (Central), Hong Kong Cancer Fund, HK

11:45 am

Multimodality Treatment of Liver CancerSheung-Tat Fan, The University of Hong Kong, HK

11:45 am

Laughter Therapy for Cancer Patients and their CarersEnda Junkins, Laughter Therapy Enterprises, USA

12:30 pm Lunch Symposium (12:45 pm – 2:00 pm) in Lecture Theatre 3

Paediatric Neuro-OncologyChairperson: Godfrey CF Chan, The University of Hong Kong, HK

12:45 pm

Childhood Brain Tumours: The Hong Kong ExperienceGodfrey CF Chan, The University of Hong Kong, HK

12:55 pm

Recent Advances in the Management of Childhood Brain TumoursEric Bouffet, University of Toronto, Canada

1:35 pm

Neurosurgical Aspect of Pediatric Brain TumourWilson WS Ho, Queen Mary Hospital, HK

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Scientific Programme 4 November 2011 Continued

4 November 2011 (Friday)

Lecture Theatre 3 Lecture Theatre 4 Seminar Room 1-2

2:00 pm –3:30 pm

SymposiumTraditional Chinese MedicineChairperson: Yao Tong, The University of Hong Kong, HK

SymposiumNursing Perspectives on Holistic Cancer CareChairpersons: Polly SL Chan, The University of Hong Kong, HKNga-Fan Shum, Queen Mary Hospital, HK

WorkshopPsychosocial Oncology (HKCF)Chairperson: Chris Ng, CancerLink Support Centre (Tin Shui Wai), Hong Kong Cancer Fund, HK

2:00 pmDiscover Anticancer Candidates from Chinese Medicines: From Screening Exploration to Mechanism StudiesYibin Feng, The University of Hong Kong, HK

2:30 pmMechanistic Investigation of the Anti-cancer and Anti-hyperlipidemia Effects of Gynostemma Triterpenoids Using Systems Biology ApproachWendy WL Hsiao, Hong Kong Baptist University, HK

2:00 pmMoving Beyond Words: Systematic Review of Body-Mind-Spirit Interventions and Exercise Qigong in Curative, Palliative and Rehabilitative Cancer CareCecilia LW Chan, The University of Hong Kong, HK

2:15 pmMoving Beyond Words: Dance Movement Therapy for Cancer PatientsRainbow TH Ho, The University of Hong Kong, HK

2:30 pmHealth-Care Professionals’ Perspective on Hope in the Palliative Care SettingLai-Ngor Chan, Haven of Hope Hospital, HK

2:45 pmA Retrospective Observational Study for the Prevention of Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell TransplantationSo-Kwan Fong, Queen Mary Hospital, HK

3:00 pmMeaning Focused-Intervention for Advanced Cancer PatientsTheresa TK Lai, Princess Margaret Hospital, HK

3:15 pmImproving End of Life Care in Acute Care Wards: Challenges and Roles of Different Health Care ProfessionalsSteven WK Siu, Queen Mary Hospital, HK

3:30 pmQ&A Session

2:00 pmOptimising Quality of Care for People Across the Cancer Journey: A Needs-based ApproachAfaf Girgis, University of New South Wales, Australia

State-of-the-Art LectureTraditional Chinese MedicineChairperson: Yao Tong, The University of Hong Kong, HK

3:00 pmHerbs Therapy in Pancreatic CancerLuming Liu, Fudan University, China

3:30 pm Coffee Break

Lecture Theatre 3 Lecture Theatre 4 Seminar Room 1-2

4:00 pm –5:30 pm

SymposiumCancer Pain ManagementChairperson: Michael G Irwin, The University of Hong Kong, HK

SymposiumPublic Health Perspectives on Cancer Treatment and ControlChairperson: Wendy WT Lam, The University of Hong Kong, HK

WorkshopPsychosocial Oncology (HKCF)Chairperson: Chris Ng, CancerLink Support Centre (Tin Shui Wai), Hong Kong Cancer Fund, HK

4:00 pmPathogenesis of Cancer PainMichael G Irwin, The University of Hong Kong, HK

4:30 pmGeneral Management of Cancer PainChi-Wai Cheung, The University of Hong Kong, HK

4:00 pmEpidemiological Characteristics of HPV Infection and Cervical Cancer in Hong KongPaul KS Chan, The Chinese University of Hong Kong, HK

4:30 pmResource Allocation for Breast Cancer Prevention and Care in Hong KongIrene OL Wong, The University of Hong Kong, HK

4:00 pmLaughter Therapy for Cancer Patients and their CarersEnda Junkins, Laughter TherapyEnterprises, USA

5:00 pmInterventional Procedures for Cancer Pain ManagementSteven Wong, Queen ElizabethHospital, HK

5:00 pmContemporary Epidemiology of Nasopharyngeal Carcinoma: A Life Course PerspectiveWill YH Chan, The University of Hong Kong, HK

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Scientific Programme| 5 November 2011 |

5 November 2011 (Saturday)

Lecture Theatre 3

9:30 am CCR LectureChairperson: Zhenguo Wu, The Hong Kong University of Science and Technology, HK

Circulating MicroRNA, Secreted MicroRNA and Exogenous Plant MicroRNAChen-Yu Zhang, Nanjing University, China

10:30 am Coffee BreakSponsored by Novartis Pharmaceuticals (HK) Limited

Lecture Theatre 3 Lecture Theatre 4

11:00 am -12:30pm

State-of-the-Art LectureTumour MicroenvironmentChairperson: George SW Tsao, The University of Hong Kong, HK

State-of-the-Art LecturePsychosocial Oncology (SPHC)Chairperson: Thomas KS Wong, The Chinese University of Hong Kong – Tung Wah Group of Hospitals Community College, HK

11:00 am

Next Generation Living Tumour Models for Discovery, Drug Development and BeyondYuzhuo Wang, University of British Columbia, Canada

11:00 am

Improving Palliative Care Patient Outcomes Across the Health SystemDavid Currow, Cancer Institute NSW, Australia

State-of-the-Art LectureTumour MicroenvironmentChairperson: George SW Tsao, The University of Hong Kong, HK

SymposiumPsychosocial Oncology (SPHC)Chairperson: Thomas KS Wong, The Chinese University of Hong Kong – Tung Wah Group of Hospitals Community College, HK

11:45 am

Adipokines – Toward the Molecular Dissection of Interactions Between Stromal Adipocytes and Breast Cancer CellsYu Wang, The University of Hong Kong, HK

11:45 noon

Impact of Palliative Care on Advanced Cancer Patients in Hong KongMichael MK Sham, Grantham Hospital, HK

12:05 noon

What Heals in the End-of-life? Spiritual Intervention for Advanced Cancer Patients in the Chinese Cultural ContextPamela PY Leung, The University of Hong Kong, HK

12:25 pm

Q&A Session

12:30 pm –2:00 pm

Lunch Symposium (12:45 pm – 1:45 pm) in Lecture Theatre 4

SPHC Overseas Sponsorship Recipients’ Sharing SessionChairperson: Betty Fung, Society for the Promotion of Hospice Care, HK

12:45 pm

Introduction

12:55 pm

Sharing on Educational Trip in London for Multi-Professional Week at St Christopher’s Hospice and Clinical Attachment at St Joseph’s HospiceTai-Chung Lam, Tuen Mun Hospital, HK

1:15 pm

Sharing on Educational Trip in London for Clinical Attachment at St Christopher’s HospiceCarol CY Cheng, Society for the Promotion of Hospice Care, HK

1:35 pm

Q & A Session

[Sponsored by The TUYF Charitable Trust]

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Scientific Programme 5 November 2011 Continued

5 November 2011 (Saturday)

Lecture Theatre 3 Lecture Theatre 4 Seminar Room 1-2

2:00 pm –3:30 pm

State-of-the-Art LectureCancer Diagnosis – The Role of Family MedicineChairperson: Jun Liang, The Hong Kong College of Family Physicians, HK

Educational SymposiumCancer BiologyChairpersons: Pek-Lan Khong, The University of Hong Kong, HKMaria P Wong, The University of Hong Kong, HK

WorkshopPsychosocial Oncology(SPHC)Chairperson: Annie OL Kwok, Caritas Medical Centre, HK

2:00 pm

Earlier Cancer Diagnosis - How can Family Medicine Contribute?Jon Emery, The University of Western Australia, Australia

2:00 pm

Epithelial-Mesenchymal Transition (EMT) and HCC MetastasisXin-Yuan Guan, The University of Hong Kong, HK

2:30 pm

Inflammation and CancerKwan Man, The University of Hong Kong, HK

3:00 pm

Molecular Basis of Positron Emission Tomography in CancerDavid WC Yeung, The University ofHong Kong, HK

2:00 pm

Conducting Clinical Research in Palliative CareDavid Currow, Cancer Institute NSW,Australia

SymposiumCancer Diagnosis – The Role of Family MedicineChairperson: Jun Liang, The Hong Kong College of Family Physicians, HK

3:00 pm

Early Diagnosis of Nasopharyngeal Carcinoma in Primary CareJun Liang, The Hong Kong College of Family Physicians, HK

3:30 pm Coffee BreakSponsored by Novartis Pharmaceuticals (HK) Limited

Lecture Theatre 3 Lecture Theatre 4 Seminar Room 1-2

4:00 pm –5:30 pm

State-of-the-Art LectureGynaecological CancerChairperson: Karen KL Chan, The University of Hong Kong, HK

SymposiumGastrointestinal OncologyChairpersons: Wai-Keung Leung, The University of Hong Kong, HKThomas CC Yau, The University ofHong Kong, HK

WorkshopPsychosocial Oncology(SPHC)Chairperson: Yvonne Mak, Bradbury Hospice, HK

4:00 pm

What Determines the Uptake of Clinical Research Findings into Clinical PracticeEdward L Trimble, National Cancer Institute, USA

4:00 pm

Translational Aspects of Novel Therapeutics for Hepatocellular CarcinomaGhassan K Abou-Alfa, MemorialSloan-Kettering Cancer Center, USA[Sponsored by Bayer HealthCare Ltd]

4:35 pm

New Developments in the Treatment of Pancreas AdenocarcinomaEileen M O’Reilly, MemorialSloan-Kettering Cancer Center, USA[Sponsored by GlaxoSmithKline Ltd]

5:10 pm

Management of Refractory Colorectal Cancer: What is on the Horizon?Thomas CC Yau, The University of Hong Kong, HK

4:00 pm

Narrative Therapy on Palliative Patients and their FamiliesValda WC Cho, Caritas Medical Centre, HK

Honoring Life through Narrative JourneyCatherine YC Tsang, Bradbury Hospice, HK

SymposiumGynaecological CancerChairperson: Karen KL Chan,The University of Hong Kong, HK

4:40 pm

What is the Optimal Treatment in Advanced Ovarian Cancer?Ka-Yu Tse, Queen Mary Hospital, HK

5:05 pm

Brachytherapy for Cancer of Cervix: Advances and ObstaclesSteven WK Siu, Queen Mary Hospital, HK