SCIENCENEWS & COMMENT -i

Trial Set to Focus on Peer Review

All Together for Quantum Computing

Australia: Science Holds On in NewBudget

DOE Gives $47 Million for CoreResearch

Chess: Web Pits One Against theWorld

Russian Science: New R&D ChiefAsserts His Authority

New 'Basic Research' Chief at NIH

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RESEARCH NEWS vm

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Debating the Big Questions

Protein Builds Second Skeleton

Drug's Link to Genes RevealsEstrogen's Many Sides

Three-Dimensional Images AreConjured in a Crystal Cube

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AMERICANASSOCIATION FOR THEADVANCEMENT OFSCIENCE

New Electron Emitters May Slim Down 1173Computer Displays

Crystallographers Pinpoint WhatGoes Where

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PERSPECTIVES

Synthetic Aperture Radar forGeodesyC. Meade and D. T. Sandwell

Trypanosome RNA Editing:ResolvedB. Sollner-Webb

Triggering Bacterial VirulenceP. A. Cotter and J. F. Miller

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RESEARCH ARTICLESA Three-Color, Solid-State, r 1185Three-Dimensional DisplayE. Downing, L. Hesselink, J. Ralson, R.Macfarlane

RNA Editing: A Mechanism for r 1189gRNA-Specified Uridylate Insertioninto Precursor mRNAM. L. Kable, S. D. Seiwert, S. Heidmann, K.Stuart

DEPARTMENTSTHIS WEEK IN SCIENCE 1149

EDITORIAL 1153HMOs and AHCs-In Defense ofTown and GownR. T. Rubin

LETTERS 1155Redundant Genome Sequencing?: J. E. Davies *Electrons and Sex: P. Abramson and S. D. Pinkerton* Predicting Career Success: M. O'Brecht and H.Friesen * Science: The Broader Context: A. Fausto-Sterling; M. Shodell; P. T. Macklem; A. Scheinman

SCIENCESCOPE 1161

RANDOM SAMPLES 1177The Next Hawaiian Island? * Stalling GangreneWith Gene Therapy * Trade Skirmish HobblesModelers

BOOK REVIEWS 1178Zapotec Civilization, reviewed by R. N. Zeitlin 9

Molecular Basis of Virus Evoluiion, D. M. Hillis aAlso Noteworthy * Books Received

AAAS NEWS & NOTES

PRODUCTS & MATERIALS

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AAAS Board of DirectorsRita R. Colwell Sheila Jasanoff William T. Golden * SCIENCE (ISSN 0036-8075) is published weekly on Friday, except the last week inRetiring President, Chairman William A. Lester Jr. Treasurer December, by the American Association for the Advancement of Science, 1200 New York

Jane Lubchenco Simon A. Levin Richard S. Nicholson Avenue, NW, Washington, DC 20005. Periodicals Mail postage (publication No. 484460) paid atPresident Marcia C. Linn Executive Officer Washington, DC, and additional mailing offices. Copyright © 1996 by the American Association for

Mildred S. DresselhausMichael J. Novacek ~~~the Advancement of Science. The title SCIENCE is a registered trademark of the AAAS. DomesticMildred S. Dresselhaus Michael J. Novacek individual membership ands asubscription (51 issues): $102 ($55 allocated to subscription). Domestic

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ISSN 0036-807530 AUGUST 1996VOLUME 273NUMBER 5279

1183, 1231& 1234Host-pathogen c_ross ,-,alk

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COVERSurface displacement since the 1992 Landers, Califor- upper left. Such deformation may be caused by pore fluidnia, earthquake obtained by interferometric processing of flow as pore pressure gradients induced by the earth-ERS-1 satellite radar images. Maximum range displace- quake deformation dissipate. Image width is -40 km. Seement of -5 cm (blue through red to green) is localized in page 1202 and the Perspective on imaging on pagestep-overs of the 1 992 surface break, from lower rght to 1 181. [Image: Courtesy of the Jet Propulsion Laboratory]

REPORTS __m WIin_iXmu_inu_u_u_uuuuuXumu_iL--

Phase and Morphology Changes 1196in Lipid Monolayers Induced by SP-BProtein and Its Amino-Terminal PeptideM. M. Lipp, K. Y. C. Lee, J. A. Zasadzinski,A. J. Waring

Attomole Protein Characterization 1199by Capillary Electrophoresis-MassSpectrometryG. A. Valaskovic, N. L. Kelleher, F. W.McLafferty

Postseismic Rebound in Fault rStep-Overs Caused by Pore Fluid FlowG. Peltzer, P. Rosen, F. Rogez, K. Hudnut

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The Metabolic Status of Some Late 1204Cretaceous Dinosaurs

J. A. Ruben, W. J. Hillenius, N. R. Geist, A.Leitch, T. D. Jones, P. J. Currie, J. R. Homer,G. Espe III

Enforcing Coherent Evolutilon inDissipative Quantum DynamicsJ. I. Cirac, T. Pellizzari, P. Zoller

Flux Line Lattice Melting Transitionin YBa2Cu306.94 Observed in SpecificHeat ExperimentsM. Roulin, A. Junod, E. Walker

Allel'ic Diversilty and Gene Genealogyat the Self-Incompatibility Locus in theSolanaceae

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A. D. Richman, M. K. Uyenoyama, J. R. Kohn

Forskolin Stimulation of Water andCation Permeability in AquaporinlWater ChannelsA. J. Yool, W. D. Stamer, J. W. Regan

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Luteinizing Hormone Deficiency and 1219Female Infertility in Mice Lacking theTranscription Factor NGFI-A (Egr-l)S. L. Lee, Y. Sadovsky, A. H. Swirnoff, J. A.Polish, P. Goda, G. Gavrilina, J. Milbrandt

Identification of an Estrogen r 1222Response Element Activated by Metabolitesof 1 713-Estradiol and RaloxifeneN. N. Yang, M. Venugopalan, S. Hardikar, A.Glasebrook

Tourette Syndrome: Prediction of 1225Phenotypic Variation in Monozygotic Twinsby Caudate Nucleus D2 Receptor BindingS. S. Wolf, D. W. Jones, M. B. Knable, J. G.Gorey, K. S. Lee, T. M. Hyde, R. Coppola, D.R. Weinberger

KUZ, a Conserved Metalloprotease- 1227Disintegrin Protein with Two Roles inDrosophila Neurogenesis

J. Rooke, D. Pan, T. Xu, G. M. Rubin

Modulation of Virulence Factor ! 1231Expression by Pathogen Target Cell Contact

J. Pettersson, R. Nordfelth, E. Dubinina, T.Bergman, M. Gustafsson, K. E. Magnusson, H.Wolf-Watz

Induction of Gene Expression in r: 1234Escherichia coli After Pilus-MediatedAdherence

J. P. Zhang and S. Normark

Pycnodysostosis, a Lysosomal Disease 1236Caused by Cathepsin K DeficiencyB. D. Gelb, G.-P. Shi, H. A. Chapman, R. J.Desnick

A Protein Farnesyl Transferase Involved 1239in Abscisic Acid Signal Transduction inArabidopsisS. Cutler, M. Ghassemian, D. Bonetta, S.Cooney, P. McCourt

TECHNICAL COMMENTSCD2: An Exception to the 1241Immunoglobulin Superfamily Concept?S. J. Davis and P. A. van der Merwe; E. L.Reinherz, J. Li, A. Smoylar, D. F. Wyss, M. H.Knoppers, K. J. Willis, A. R. N. Arulanandam,J. S. Choi, G. Wagner

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On the WebMovie of a three-color solid-state3D display by Downing et al.http://www.sciencemag.org/science/scripts/display/short/273/5279/1 1 85.htm

SCIENCE * VOL. 273 * 30 AUGUST 1996

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