Upload
others
View
1
Download
0
Embed Size (px)
Citation preview
SCHWERPUNKT: Myome und Endometriose
Uterusmyome in der Schwangerschaft (S. 7–12)
L. K. Platzer, S.Wallwiener, M.Wallwiener
Literatur:
1. Qidwai GI et al. Jacoby, Obstetric outcomes in women with sonographically identified uterine
leiomyomata. Obstet Gynecol 2006; 107(2 Pt 1): 376–82
2. Exacoustos C & Rosati P. Ultrasound diagnosis of uterine myomas and complications in
pregnancy. Obstet Gynecol 1993; 82(1): 97–101
3. Strobelt N. et al. Natural history of uterine leiomyomas in pregnancy. J Ultrasound Med 1994;
13(5): 399–401
4. Laughlin SK et al. Prevalence of uterine leiomyomas in the first trimester of pregnancy: an
ultrasound-screening study. Obstet Gynecol 2009; 113(3): 630–5
5. Stout MJ et al. Leiomyomas at routine second-trimester ultrasound examination and adverse
obstetric outcomes. Obstet Gynecol 2010; 116(5): 1056–63
6. Terry KL et al. Reproductive characteristics and risk of uterine leiomyomata. Fertil Steril 2010;
94(7): 2703–7
7. Guo XC & Segars JH. The impact and management of fibroids for fertility: an evidence-based
approach. Obstet Gynecol Clin North Am 2012; 39(4): 521–33
8. Laughlin SK et al. Postpartum factors and natural fibroid regression. Am J Obstet Gynecol
2011; 204(6): 496 e1–6
9. Lam, SJ. The impact of fibroid characteristics on pregnancy outcome. Am J Obstet Gynecol
2014; 211(4): 395 e1–5
10. Rice, JP et al. The clinical significance of uterine leiomyomas in pregnancy. Am J Obstet
Gynecol 1989; 160(5 Pt 1): 1212–6
11. Cooper NP & Okolo S. Fibroids in pregnancy--common but poorly understood. Obstet
Gynecol Surv 2005; 60(2): 132–8
12. Muram D. Myomas of the uterus in pregnancy: ultrasonographic follow-up. Am J Obstet
Gynecol 1980; 138(1): 16–9
13. Segars JH et al. Proceedings from the Third National Institutes of Health International
Congress on Advances in Uterine Leiomyoma Research: comprehensive review, conference summary
and future recommendations. Hum Reprod Update 2014; 20(3): 309–33
14. Parker WH. Etiology, symptomatology, and diagnosis of uterine myomas. Fertil Steril; 2007;
87(4): 725–36
15. Katz, VL. Complications of uterine leiomyomas in pregnancy. Obstet Gynecol 1989. 73(4):
593–6
16. Dildy G Aet al. Indomethacin for the treatment of symptomatic leiomyoma uteri during
pregnancy. Am J Perinatol 1992; 9(3): 185–9
17. Benson CB et al. Outcome of pregnancies in women with uterine leiomyomas identified by
sonography in the first trimester. J Clin Ultrasound 2001; 29(5): 261–4
18. Wallach EE & Vu KK. Myomata uteri and infertility. Obstet Gynecol Clin North Am 1995;
22(4): 791–9
19. Blum M. Comparative study of serum CAP activity during pregnancy in malformed and
normal uterus. J Perinat Med 1978; 6(3): 165–8
20. Klatsky PC et al. Fibroids and reproductive outcomes: a systematic literature review from
conception to delivery. Am J Obstet Gynecol 2008; 198(4): 357–66
21. Girault A et al. Leiomyomatous uterus and preterm birth: an exposed/unexposed
monocentric cohort study. Am J Obstet Gynecol 2018; 219(4): 410 e1–410
22. Coronado GD et al. Complications in pregnancy, labor, and delivery with uterine leiomyomas:
a population-based study. Obstet Gynecol 2000. 95(5): 764–9
23. Winer-Muram HT. Uterine myomas in pregnancy. J Can Assoc Radiol 1984. 35(2): 168–70
24. Vergani P et al. Do uterine leiomyomas influence pregnancy outcome? Am J Perinatol, 1994;
11(5): 356–8
25. Sheiner E et al. Higher rates of tachysystole among patients with clinically apparent uterine
leiomyomas. Am J Obstet Gynecol 2004. 191(3): 945–8
26. Szamatowicz J et al. Fibromyomas and uterine contractions. Acta Obstet Gynecol Scand,
1997; 76(10): 973–6
27. Roberts WE et al. The impact of leiomyomas on pregnancy. Aust N Z J Obstet Gynaecol 1999;
39(1): 43–7
28. Graham JM et al. Limb reduction anomalies and early in utero limb compression. J Pediatr
1980. 96(6): 1052–6
29. Romero R et al. Fetal head deformation and congenital torticollis associated with a uterine
tumor. Am J Obstet Gynecol 1981; 141(7): 839–40
30. Matsunaga E & Shiota K, Ectopic pregnancy and myoma uteri: teratogenic effects and
maternal characteristics. Teratology 1980; 21(1): 61–9
31. Daniel S et al. Fetal exposure to nonsteroidal anti-inflammatory drugs and spontaneous
abortions. CMAJ 2014. 186(5): E177–82
32. Kwon SY et al. Management of severely painful uterine leiomyoma in a pregnant woman with
epidural block using a subcutaneous injection port. Acta Obstet Gynecol Scand 2014; 93(8): 839
33. Moridaira T et al. A case of continuous epidural anesthesia for pain relief in a pregnant
woman with uterine myoma in the second trimester of pregnancy. Masui 2013; 62(10): 1253–6
34. Tropeano G et al. Non-surgical management of uterine fibroids. Human Reproduction Update
2008. 14(3): 259–74
35. Walker WJ & McDowell SJ, Pregnancy after uterine artery embolization for leiomyomata: a
series of 56 completed pregnancies. American Journal of Obstetrics and Gynecology 2006; 195(5):
1266–71
36. Mara M et al. Midterm clinical and first reproductive results of a randomized controlled trial
comparing uterine fibroid embolization and myomectomy. Cardiovascular and Interventional
Radiology 2008; 31(1): 73–85
37. Goldberg J & Pereira L. Pregnancy outcomes following treatment for fibroids: uterine fibroid
embolization versus laparoscopic myomectomy. Current Opinion in Obstetrics and Gynecology 2006.
18(4): 402–6
38. Pron G et al. Pregnancy after uterine artery embolization for leiomyomata: the Ontario
multicenter trial. Obstetrics and Gynecology 2005. 105(1): 67–76
39. Pergialiotis V et al. Perioperative Complications of Cesarean Delivery Myomectomy: A Meta-
analysis. Obstet Gynecol 2017; 130(6): 1295–1303
40. Leach K et al. First trimester myomectomy as an alternative to termination of pregnancy in a
woman with a symptomatic uterine leiomyoma: a case report. J Med Case Rep 2011; 5(1): 571
41. De Carolis S et al. Uterine myomectomy in pregnant women. Fetal Diagn Ther 2001; 16(2):
116–9
42. Tower AM & Cronin B. Myomectomy after a vaginal delivery to treat postpartum hemorrhage
resulting from an intracavitary leiomyoma. Obstet Gynecol 2015; 125(5): 1110–3
43. Tian J & Hu W. Cervical leiomyomas in pregnancy: report of 17 cases. Aust N Z J Obstet
Gynaecol 2012; 52(3): 258–61
44. ACOG Committee Opinion No. 764: Medically Indicated Late-Preterm and Early-Term
Deliveries. Obstet Gynecol 2019; 133(2): e151–e155
Grüntee in der Frauenheilkunde (S. 14–17)
J. Huber
Literatur:
1. Baxter, GJ et al. Salicylic acid in soups prepared from organically and non-organically grown
vegetables. European journal of nutrition 2001; 40(6): 289–292
2. Na, HK & Surh YJ. Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by
the green tea polyphenol EGCG. Food and Chemical Toxicology 2008; 46(4): 1271–1278
3. Ahn WS et al. Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical
lesions. European journal of cancer prevention 2003; 12(5): 383–390
4. Zhang W et al. Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis.
Medical science monitor: international medical journal of experimental and clinical research 2014;
20, 2142
5. Min NY et al. Selective death of cancer cells by preferential induction of reactive oxygen species in
response to (-)-epigallocatechin-3-gallate. Biochemical and biophysical research communications
2012; 421(1): 91–97
6. Gianfredi V et al. Sulforaphane and epigallocatechin gallate restore estrogen receptor Expression
by modulating epigenetic events in the breast cancer cell line MDA-MB-231: a systematic review and
meta-analysis. Lifestyle Genomics 2017; 10(3–4): 126–135
7. Rafieian-Kopaei M & Movahedi M. Breast cancer chemopreventive and chemotherapeutic effects
of Camellia Sinensis (green tea): an updated review. Electronic physician 2017; 9(2): 3838
8. Zhou Q et al. Green tea, black tea consumption and risk of endometrial cancer: a systematic review
and meta-analysis. Archives of gynecology and obstetrics 2016; 293(1): 143–155
9. Laschke MW et al. Epigallocatechin-3-gallate inhibits estrogen-induced activation of endometrial
cells in vitro and causes regression of endometriotic lesions in vivo. Human Reproduction 2008;
23(10): 2308–2318
10. Zhang D et al. Antiproliferative and proapoptotic effects of epigallocatechin gallate on human
leiomyoma cells. Fertility and sterility 2010, 94(5), 1887–1893
11. Ciebiera M et al.Alternative oral agents in prophylaxis and therapy of uterine fibroids—an up-to-
date review. International journal of molecular sciences 2017; 18(12): 2586
12. Guo M et al. Tea consumption may decrease the risk of osteoporosis: an updated meta-analysis
of observational studies. Nutrition Research 2017; 42, 1–10
13. Vázquez LC. Effects of green tea and its epigallocatechin (EGCG) content on body weight and fat
mass in humans: a systematic review. Nutr Hosp 2017; 34(3): 731–737. doi: 10.20960/nh.753
14. Liu YC. Modulation effect of tea consumption on gut microbiota. Applied Microbiology and
Biotechnology 2020; 104(3): 981–987
15. Wang S. Novel insights of dietary polyphenols and obesity. The Journal of nutritional biochemistry
2014, 25(1), 1–18
Operative Therapie der tief infiltrierenden Endometriose: eine Übersicht (S. 18–23)
R.Schmädecker, U. A. Ulrich
Literatur:
1. Reich H et al. Laparoscopic treatment of cul-de-sac obliteration secondary to retrocervical deep
fibrotic endometriosis. J Reprod Med 1991 Jul; 36(7): 516–22
2. Koninckx PR & Martin D. Treatment of deeply infiltrating endometriosis.
Curr Opin Obstet Gynecol 1994 Jun; 6(3): 231–41
3. Akladios C al. Is ileostomy always necessary following rectal resection for deep infiltrating
endometriosis? J Minim Invasive Gynecol 2015; 22(1): 103–9
4. Coccia ME & Rizzello F. Ultrasonographic staging: a new staging system for deep endometriosis.
Ann N Y Acad Sci 20111221: 61–9
5. Wolthuis AM et al. Bowel endometriosis: colorectal surgeon’s perspective in a multidisciplinary
surgical team. World J Gastroenterol 2014; 20(42): 15616–23
6. Wustlich M. Laparoskopisch-assistierte Sigmasegmentresektion bei Endometriose mit
Darmbeteiligung. Leipzig: Universität; 2002
7. Keckstein J et al. ENZIAN-Klassifikation der tief infiltrierenden Endometriose. Zentralbl Gynäkol
2003; 125: 291
8. Ulrich U et al. National German Guideline (S2k): Guideline for the diagnostic and treatment of
endometriosis: Long Version – AWMF Registry No. 015-045. Geburtshilfe Frauenheilkd 2014; 74(12):
1104–18
9. Ebert AD et al. Implementation of Certified Endometriosis Centers: 5-Year Experience in German-
Speaking Europe. Gynecol Obstet Invest 2013; 76 (1): 4–9
10. Hudelist G et al. Diagnostic accuracy of transvaginal ultrasound for non-invasive diagnosis of
bowel endometriosis: systematic review and meta-analysis. Ultrasound Obstet Gynecol 2011; 37(3):
257–63
11. Jacobson TZ et al. Laparoscopic surgery for pelvic pain associated with endometriosis. Cochrane
Database Syst Rev 2009; (4): CD001300
12. Abrão MS et al. Deep endometriosis infiltrating the recto-sigmoid: critical factors to consider
before management. Hum Reprod Update 2015; 21(3): 329–39
13. Kavallaris A et al. Laparoscopic nerve-sparing surgery of deep infiltrating endometriosis:
description of the technique and patients' outcome. Arch Gynecol Obstet. 2011; 284(1): 131–5
14. Ceccaroni M et al. Laparoscopic nerve-sparing transperitoneal approach for endometriosis
infiltrating the pelvic wall and somatic nerves: anatomical considerations and surgical technique.
Surg Radiol Anat 2010; 32(6): 601–4
15. Volpi E et al. Laparoscopic identification of pelvic nerves in patients with deep infiltrating
endometriosis. Surg Endosc 2004; 18(7): 1109–12
16. Alborzi S et al. A prospective, randomized study comparing laparoscopic ovarian cystectomy
versus fenestration and coagulation in patients with endometriomas. Fertil Steril 2004; 82(6): 1633–7
17. Hart RJ. Excisional surgery versus ablative surgery for ovarian endometriomata. Cochrane
Database Syst Rev 2008; (2) :CD004992
18. Donnez O & Roman H. Choosing the right surgical technique for deep endometriosis: shaving, disc
excision, or bowel resection? Fertil Steril. 2017; 108(6): 931–942
19. Maccagnano C et al. Ureteral endometriosis: proposal for a diagnostic and therapeutic algorithm
with a review of the literature. Urol Int 2013; 91(1): 1–9
20. Barra F et al. Ureteral endometriosis: a systematic review of epidemiology, pathogenesis,
diagnosis, treatment, risk of malignant transformation and fertility. Hum Reprod Update 2018; 24(6)
:710–730
21. Nezhat C et al. Multidisciplinary treatment for thoracic and abdominopelvic endometriosis. JSLS
2014; 18(3). pii: e2014.00312.
22. Roman H et al. Laparoscopic management of diaphragmatic endometriosis by three different
approaches. Fertil Steril 2016; 106(2): e1
23. Riiskjær M et al. Bowel Endometriosis Syndrome: a new scoring system for pelvic organ
dysfunction and quality of life. Hum Reprod 2017; 32(9): 1812–1818
24. Turco LC et al. Long-term evaluation of quality of life and gastrointestinal well-being after
segmental colo-rectal resection for deep infiltrating endometriosis (ENDO-RESECT QoL). Arch
Gynecol Obstet 2019. doi: 10.1007/s00404-019-05382-8
Endometriose und Infertilität – Ätiologie, Pathomechanismen und
Paradigmenwechsel in der Kinderwunschtherapie (S. 24–32)
M. Murtinger, B. Wirleitner, A. Damko, M. Schuff , F. Kentros, J. Okhowat, D. Spitzer
Literatur:
1. Zegers-Hochschild F et al. The International Glossary on Infertility and Fertility Care, 2017.
Hum Reprod 2017;32: 1786–1801
2. Shroen D: Disputatio Inauguralis Medica de Ulceribus Ulceri. 1690
3. Dunselman GA et al. ESHRE guideline: management of women with endometriosis. Hum
Reprod 2014; 29: 400–12
4. Johnston Taylor S. Underfunded, But Undeterred: Women Raise Money for Endometriosis
Research. Endometriosis Foundation of America 2018. (https://www.endofound.org/underfunded-
not-undeterred-women-raise-money-for-endometriosis-research). Zugegriffen: 15.01.2020
5. Sutton C & Jones K. Endometriosis. Cambridge University Press 2014; 1–8
6. Leyendecker G et al. The pathophysiology of endometriosis and adenomyosis: tissue injury
and repair. Arch Gynecol Obstet 2009; 280: 529–38
7. Saha R et al. Heritability of endometriosis. Fertil Steril 2015; 104: 947–952
8. Bougie O et al. Influence of race/ethnicity on prevalence and presentation of
endometriosis: a systematic review and meta-analysis. BJOG 2019; 126: 1104–1115
9. Fung JN & Montgomery GW. Genetics of endometriosis: State of the art on genetic risk
factors for endometriosis. Best Pract Res Clin Obstet Gynaecol 2018; 50: 61–71
10. Exacoustos C et al. Isolated Ovarian Endometrioma: A History Between Myth and Reality. J
Minim Invasive Gynecol 2018; 25: 884–891
11. Vercellini P et al. Is cystic ovarian endometriosis an asymmetric disease? Br J Obstet
Gynaecol 1998; 105: 1018–21
12. Gordts S et al. Pathogenesis of deep endometriosis. Fertil Steril 2017; 108: 872–885
13. American Society for Reproductive Medicine. Revised American Society for Reproductive
Medicine classification of endometriosis: 1996. Fertil Steril 1997; 67: 817–21
14. Mettler L & Semm K. Three step medical and surgical treatment of endometriosis. Ir J Med
Sci 1983; 152 Suppl 2: 26–8
15. Klugsberger B et al. Clinical Outcome after Colonic Resection in Women with Endometriosis
Biomed Res Int 2015; 2015: 514383
16. Adamson GD & Pasta DJ. Endometriosis fertility index: the new, validated endometriosis
staging system. Fertil Steril 2010 ;94: 1609–15
17. Buchweitz O et al. Interobserver variability in the diagnosis of minimal and mild
endometriosis. Eur J Obstet Gynecol Reprod Biol 2005; 122: 213–217
18. Kennedy S et al. ESHRE guideline for the diagnosis and treatment of endometriosis. Hum
Reprod 2005; 20: 2698–704
19. Nnoaham KE et al. Impact of endometriosis on quality of life and work productivity: a
multicenter study across ten countries. Fertil Steril 2011; 96: 366–373.e8.
20. Leyendecker G & Kunz A. Endometriose und Adenomyose. Zentralbl Gynakol 2005; 127:
288–294
21. Hamdan M et al. The impact of endometrioma on IVF/ICSI outcomes: a systematic review
and meta-analysis. Hum Reprod Update 2015; 21: 809–825
22. Muzii L et al. Antimüllerian Hormone Is Reduced in the Presence of Ovarian
Endometriomas: A Systematic Review and Meta-Analysis. Fertil Steril 2018; 110: 932–940
23. Yang C et al. Impact of ovarian endometrioma on ovarian responsiveness and IVF: a
systematic review and meta-analysis. Reprod Biomed Online 2015; 31: 9–19
24. Yılmaz Hanege B et al. Endometrioma and ovarian reserve: effects of endometriomata per
se and its surgical treatment on the ovarian reserve. Facts Views Vis Obgyn 2019; 11: 151–157
25. Harb HM et al. The effect of endometriosis on in vitro fertilisation outcome: a systematic
review and meta-analysis. BJOG 2013; 120: 1308–20
26. Borges E Jr et al. Endometriosis Affects Oocyte Morphology in Intracytoplasmic Sperm
Injection Cycles? JBRA Assist Reprod 2015; 19: 235–240
27. Shebl O et al. Oocyte competence in in vitro fertilization and intracytoplasmic sperm
injection patients suffering from endometriosis and its possible association with subsequent
treatment outcome: a matched case-control study. Acta Obstet Gynecol Scand 2017; 96: 736–744
28. Garrido N et al. The endometrium versus embryonic quality in endometriosis-related
infertility. Hum Reprod Update 2002; 8: 95–103
29. Kasapoglu I et al. Detrimental effects of endometriosis on oocyte morphology in
intracytoplasmic sperm injection cycles: a retrospective cohort study. Gynecol Endocrinol 2018; 34:
206–211
30. Shahine LK et al. Embryo quality before and after surgical treatment of endometriosis in
infertile patients. J Assist Reprod Genet 2009; 26: 69–73
31. Xu B et al. Oocyte quality is decreased in women with minimal or mild endometriosis. Sci
Rep 2015; 5: 10779
32. Demirel C et al. The Presence of Endometrioma Does Not Impair Time-Lapse Morphokinetic
Parameters and Quality of Embryos: A Study On Sibling Oocytes. Reprod Sci 2016; 23: 1053–7
33. Freis A et al. Relative Morphokinetics Assessed by Time-Lapse Imaging Are Altered in
Embryos From Patients With Endometriosis. Reprod Sci 2018; 25: 1279–1285
34. Yong PJ et al. Endometriosis and Ectopic Pregnancy: A Meta-analysis. J Minim Invasive
Gynecol pii: S1553-4650(19)31205-1.
35. Leyendecker G et al. The pathophysiology of endometriosis and adeno-myosis: tissue injury
and repair. Archives of gynecology and obstetrics 2009; 280: 529–38
36. Lessey BA & Kim JJ. Endometrial receptivity in the eutopic endometrium of women with
endometriosis: it is affected, and let me show you why. Fertil Steril 2017; 108: 19–27
37. Miravet-Valenciano J et al. Endometrial receptivity in eutopic endometrium in patients
with endometriosis: it is not affected, and let me show you why. Fertil Steril 2017; 108: 28–31
38. Jana SK et al. HOXA-11 mediated dysregulation of matrix remodeling during implantation
window in women with endometriosis. J Assist Reprod Genet 2013; 30: 1505–1512
39. Schmitz CR et al. Alterations in expression of endometrial milk fat globule-EGF factor 8
(MFG-E8) and leukemia inhibitory factor (LIF) in patients with infertility and endometriosis. JBRA
Assist Reprod 2017; 21: 313–320
40. Chen I et al. Association between surgically diagnosed endometriosis and adverse
pregnancy outcomes. Fertil Steril 2018; 109: 142–147
41. Younes G & Tulandi T. Effects of adenomyosis on in vitro fertilization treatment outcomes:
a meta-analysis. Fertil Steril 2017; 108: 483–490.e3
42. Barbosa MA et al. Impact of endometriosis and its staging on assisted reproduction
outcome: systematic review and meta-analysis. Ultrasound Obstet Gynecol 2014; 44: 261–78
43. Arbeitsgruppe „Leitlinie für die Diagnostik und Therapie der Endometriose“ der Deutschen,
Österreichischen, Schweizerischen und Tschechischen Gesellschaften für Gynäkologie und
Geburtshilfe unter Mitarbeit der Stiftung Endometrioseforschung (SEF) und der Europäischen
Endometriose Liga (EEL). Diagnostik und Therapie der Endometriose. AWMF Nr.: 015/045. 2013
44. Schweppe KJ. Therapie der Endometriose unter Berücksichtigung der Aktivitätsgrade. Der
Gynäkologe. 2002; 35: 255–261
45. Elizur SE et al. Cryopreservation of oocytes in a young woman with severe and
symptomatic endometriosis: a new indication for fertility preservation. Fertil Steril 2009; 91:
293.e1-293.e3
Zusatzthema: Wechseljahrsbeschwerden
Phytopharmaka bei Wechseljahrsbeschwerden: Wirksamkeit und Nutzen-Risiko-
Abwägung (S. 33–39)
K. Jenett-Siems
Literatur:
1. Boblitz N. Therapie klimakterischer Beschwerden mit Cimicifuga racemosa: Erkenntnisse zu Wirkung und Wirksamkeit. J
Menopause 2002; 9: 20–25
2. Wuttke W, Seidlová-Wuttke D, Gorkow C. The Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind
placebo-controlled study: effects on menopause symptoms and bone markers. Maturitas 2003; 44: 67–77
3. Wuttke W, Raus K, Gorkow C. Efficacy and tolerability of the Black cohosh (Actaea racemosa) ethanolic extract BNO 1055 on
climacteric complaints: A double-blind, placebo- and conjugated estrogens-controlled study. Maturitas 2006; 55S: 83–91
4. Osmers R, Friede M, Liske E, Schnitker J, Freudenstein J, Henneicke-von Zepelin HH. Efficacy and safety of isopropanolic
black cohosh extract for climacteric symptoms. Obstet Gynecol 2005; 105: 1074–1083
5. Frei-Kleiner S, Schaffner W, Rahlfs VW, Bodmer C, Birkhäuser M. Cimicifuga racemosa dried ethanolic extract in menopausal
disorders: a double-blind placebo-controlled clinical trial. Maturitas 2005; 51: 397–404
6. Schellenberg R, Saller R, Hess L, Melzer J, Zimmermann C, Drewe J, et al. Dose-Dependent Effects of the Cimicifuga racemosa
Extract Ze 450 in the Treatment of Climacteric Complaints: A Randomized, Placebo-Controlled Study. Evid Based Complement
Alternat Med 2012; 2012: 260301
7. Newton KM, Reed SD, LaCroix AZ, Grothaus LC, Ehrlich K, Guiltinan J. Treatment of vasomotor symptoms of menopause with
black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med 2006; 145: 869–879
8. Geller SE, Shulman LP, van Breemen RB, Banuvar S, Zhou Y, Epstein G, et al. Safety and efficacy of black cohosh and red
clover for the management of vasomotor symptoms: a randomized controlled trial. Menopause 2009; 16: 1156–1166
9. Pockaj BA, Loprinzi CL, Sloan JA, Novotny PJ, Barton DL, Hagenmaier A, et al. Pilot evaluation of black cohosh for the treatment
of hot flashes in women. Cancer Invest 2004; 22: 515–521
10. Pockaj BA, Gallagher JG, Loprinzi CL, Stella PJ, Barton DL, Sloan JA, et al. Phase III doubleblind, randomized, placebo-
controlled crossover trial of black cohosh in the management of hot flashes: NCCTG Trial N01CC1. J Clin Oncol 2006; 24:
2836–2841
11. Jacobson JS, Troxel AB, Evans J, Klaus L, Vahdat L, Kinne D, et al. Randomized trial of black cohosh for the treatment of hot
flashes among women with a history of breast cancer. J Clin Oncol 2001; 19: 2739–2745
12. Tanmahasamut P, Vichinsartvichai P, Rattanachaiyanont M, Techatraisak K, Dangrat C, Sardod P. Cimicifuga racemosa extract
for relieving menopausal symptoms: a randomized controlled trial. Climacteric 2015; 18: 79–85
13. Shahnazi M, Nahaee J, Mohammad-Alizadeh-Charandabi S, Bayatipayan S. Effect of black cohosh (cimicifuga racemosa) on
vasomotor symptoms in postmenopausal women: a randomized clinical trial. J Caring Sci 2013; 2: 105–113
14. Uebelhack R, Blohmer JU, Graubaum HJ, Busch R, Gruenwald J, Wernecke KD. Black cohosh and St. John’s wort for
climacteric complaints: a randomized trial. Obstet Gynecol 2006; 107: 247–255
15. Chung DJ, Kim HY, Park KH, Jeong KA, Lee SK, Lee YI, et al. Black cohosh and St. John’s wort (GYNO-Plus) for climacteric
symptoms. Yonsei Med J 2007; 48: 289–294
16. Leach MJ, Moore V. Black cohosh (Cimicifuga spp.) for menopausal symptoms. Cochrane Database Syst Rev 2012; 9:
CD007244
17. Franco OH, Cowdhury R, Troup J, Voortman T, Kunutsor S, Kavousi M, et al. Use of Plant-Based Therapies and Menopausal
Symptoms: A Systematic Review and Meta-analysis. JAMA 2016; 315: 2554–2563
18. Laakmann E, Grajecki D, Doege K, zu Eulenburg C, Buhling KJ. Efficacy of Cimicifuga racemosa, Hypericum perforatum and
Agnus castus in the treatment of climacteric complaints: a systematic review. Gynecol Endocrinol 2012; 28: 703–709
19. Beer AM, Neff A. Differentiated evaluation of extract-specific evidence on Cimicifuga racemosa’s efficacy and safety for
climacteric complaints. Evid Based Complement Alternat Med 2013; 2013: 860602
20. Teschke R. Black cohosh and suspected hepatotoxicity: inconsistencies, confounding variables, and prospective use of a
diagnostic causality algorithm: a critical review. Menopause 2010; 17: 426–440
21. Naser B, Schnitker J, Minkin MJ, de Arriba SG, Nolte KU, Osmers R. Suspected black cohosh hepatotoxicity: no evidence by meta-
analysis of randomized controlled clinical trials for isopropanolic black cohosh extract. Menopause 2011; 18: 366–375
22. Fritz H, Seely D, McGowan J, Skidmore B, Fernandes R, Kennedy DA, et al. Black cohosh and breast cancer: a systematic
review. Integr Cancer Ther 2014; 13: 12–29
23. Vollmer G, Papke A, Zierau O. Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role
of estrogen receptors. Chin Med 2010; 5: 7
24. Wober J, Möller F, Richter T, Unger C, Weigt C, Jandausch A, et al. Activation of estrogen receptor-beta by a special extract of
Rheum rhaponticum (ERr 731), its aglycones and structurally related compounds. J Steroid Biochem Mol Biol 2007; 107: 191–
201
25. Möller F, Zierau O, Jandausch A, Rettenberger R, Kaszkin-Bettag M, Vollmer G. Subtype-specific activation of estrogen
receptors by a special extract of Rheum rhaponticum (ERr 731), its aglycones and structurally related compounds in U2OS
human osteosarcoma cells. Phytomedicine 2007; 14: 716–726
26. Heger M, Ventskovskiy BM, Borzenko I, Kneis KC, Rettenberger R, Kaszkin-Bettag M, et al. Efficacy and safety of a special extract
of Rheum rhaponticum (ERr731) in perimenopausal women with climacteric complaints: a 12 week randomized, doubleblind,
placebo-controlled trial. Menopause 2006; 13: 744–759
27. Kaszkin-Bettag M, Ventskovskiy BM, Kravchenko A, Rettenberger R, Richardson A, Heger PW, et al. The special extract ERr
731 of the roots of Rheum rhaponticum decreases anxiety and improves health state and general well-being in perimenopausal
women. Menopause 2007; 14: 270–283
28. Kaszkin-Bettag M, Ventskovskiy B, Solskyy S, Beck S, Hasper I, Kravchenko A, et al. Confirmation of the efficacy of ERr 731
in perimenopausal women with menopausal symptoms. Altern Ther Health Med 2009; 15: 24–34.
29. Kaszkin-Bettag M, Beck S, Richardson A, Heger PW, Beer AM. Efficacy of the special extract ERr 731 from rhapontic rhubarb
for menopausal complaints: a 6-month open observational study. Altern Ther Health Med 2008; 14: 32–38
30. Hasper I, Ventskovskiy BM, Rettenberger R, Heger PW, Riley DS, Kaszkin-Bettag M. Long-term efficacy and safety of the
special extract ERr 731 of Rheum rhaponticum in perimenopausal women with climacteric complaints. Menopause 2009; 16:
117–131
Korasion
Endometriose in der Adoleszenz (S. 40–43)
N. Frumkin, R. Isermann, R. Schmädecker, U. A. Ulrich
Literatur:
1. Nnoaham KE et al. Impact of endometriosis on quality of life and work productivity: a multicenter
study across ten countries. Fertil Steril 2011; 96: 366–73
2. Soliman AM et al. “Factors associated with time to endometrioses diagnosis in the United States” J
Womens Health (Larchmt) 2017; 26: 788–97
3. Janssen E et al. Prevalence of endometriosis diagnosed by laparoscopy in adolescents with
dysmenorrhea or chronic pelvic pain: a systematic review Hum Reprod Update 2013; 19:570–82
4. Laufer MR et al. Prevalence of Endometriosis in Adolescent Girls With Chronic Pelvic Pain Not
Responding to Conventional Therapy. J Pediatr Adolesc Gynecol 1997; 10: 199–202
5. Sampson, J. The development of the implantation theory for the origin of peritoneal
endometriosis. Am. J. Obstet Gynecol 1940; 40: 549–557
6. Brosens I et al. Neonatal uterine bleeding as antecedent of pelvic endometriosis. Hum Reprod
2013; 28: 2893–7
7. Meyer R. Über den Stand der Frage der Adenomyositis und Adenome im allgemeinen und
insbesondere über Adenomyositis seroepithelialis und Adenomyometritis sarcomatosa. Zbl Gynäkol
1919; 43: 745–50
8. von Recklinghausen F. Adenomyomas and cystadenomas of the wall of the uterus and tube: their
origin as remnants of the wolffian body. Wien Klin Wochenschr 1896; 8: 530
9. Leyendecker G et al. Die Archimetra als neues morphologisch-funktionelles Konzept des Uterus
sowie als Ort der Primärerkrankung bei Endometriose. Repro Med 1999; 15: 356–71
10. Sampson J. The escape of foreign material from the uterine cavity into the uterine veins.” Am J
Obstet Gynecol 1918; 78: 161–175
11. Ochsenbein N & Mueller M. Endometriose: Pathogenese, Symptomatik und Diagnostik.
Gynäkologie 2006; 03: 5–8
12. Sampson J. Metastatic or embolic endometriosis due to the menstrual dissemination of
endometrial tissue into the venous circulation. Am. J. Pathology 1927; 3: 93–110
13. Mueller M. et al.: 2,3,7,8-Tetra-chlorodibenzo-p-dioxin increases glycodelin gene and protein
expression in human endometrium. J Clin Endocrinol Metab 2005; 90: 4809–4815
14. Dun EC et al. Endometriosis in adolescents“ JSLS 2015; 19, e2015.00019
15. Marsh EE, Laufer MR. Endometriosis in premenarcheal girls who do not have an associated
obstructive anomaly. Fertil Steril 2005; 83: 758–760
16. Stuparich M, Donnellan N, Sanfilippo J. Endometriosis in the Adolescent Patient. Semin Reprod
Med. 2017; 35: 102–109
17. Matalliotakis M et al. Endometriosis in Adolescent and Young Girls: Report on a Series of 55
Cases. J Pediatr Adolesc Gynecol 2017; 30: 568–570
18. Hickey M & Balen A. Menstrual disorders in adolescence: investigation and management. Hum
Reprod Update 2003; 9: 493–504
19. Smorgick N et al. Advanced Stage Endometriosis in Adolescents and Young Women. J Pediatr
Adolesc Gynecol 2014, 27: 320–23
20. Schuster M & Mackeen D. Fetal endometriosis: a case report. Fertil Steril 2015; 103: 160–3
21. Marsh CA et al. Uterine remnants and pelvic pain in females with Mayer-Rokitansky-Küster-
Hauser syndrome. J Pediatr Adolesc Gynecol. 2013; 26: 199–202
22. De Sanctis V et al. Primary Dysmenorrhea in Adolescents: Prevalence, Impact and Recent
Knowledge. Pediatr Endocrinol Rev. 2015; 13: 512–20
23. Gerschultz KL et al. Extended cycling of combined hormonal contraceptives in adolescents:
physician views and prescribing practices. J Adolesc Health 2007; 40: 151–7
24. Stavroulis AI et al. Laparoscopic treatment of endometriosis in teenagers. Eur J Obstet Gynecol
Reprod Biol. 2006; 125: 248–50
25. Yeung P et al. Complete laparoscopic excision of endometriosis in teenagers: is postoperative
hormonal suppression necessary? Fertil Steril 2011; 95: 1909–12
26. Chapron C et al. Markers of adult endometriosis detectable in adolescence” J Pediatr Adoesc
Gynecol 2011; 24: 7–12
27. Hanssens S et al. Endometriosis in women under 25: a specific management? Minerva Med 2015;
106: 123–31
28. Tandoi I et al. High rate of endometriosis recurrence in young women. J Pediatr Adolesc Gynecol
2011; 24: 376–9
29. Ventolini G et al. Endometriosis in adolescence: A long-term follow-up fecundability assessment.
RBEJ 2005; 3: 1–4
30 Liu X et al. Patterns of and risk factors for recurrence in women with ovarian endometriomas.
Obstet Gynecol 2007, 109: 1411–20
31 Melin A et al. Endometriosis and the risk of cancer with special emphasis on ovarian cancer. Hum
Reprod 2006; 21: 1237–42
32 Zannoni L et al. Dysmenorrhea, absenteeism from school, and symptoms suspicious for
endometriosis in adolescents. J Pediatr Adolesc Gynecol 2014; 27: 258–65