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2 minutes pour convaincre Sébastien JACQUET, PhD Delpharm Development Early Development Solutions Mob: 06 07 16 25 61 92100 Boulogne Billancourt [email protected]

Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

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Page 1: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Sébastien JACQUET, PhDDelpharm DevelopmentEarly Development Solutions

Mob: 06 07 16 25 6192100 Boulogne [email protected]

Page 2: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

DELPHARM

• French CDMO, 3400 employees, 500m€ Revenues

• Financial stability (100% Management owned)

• 3 Development Centers (90 employees), 12 manufacturing

sites in Europe

• Most dosage Forms (Liquid, Semi solid, Solid)

Page 3: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Early Development Solutions• Early formulation toolkit for poor solubility API (BCS Class II,IV)

• Non GMP pilot for fast and preliminary assay

• Small Scale Batch Size GMP Manufacturing (100g to 50kg)

• Ph1-3 Clinical Batch Supply

• Analytical Methods Development and Validation

• Stability studies

• Quality by Design (QbD) process development

• Regulatory Affairs and Packaging expert in-house

Page 4: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Delpharm Development• Geographical proximity (French sites)

• Start-up to big pharma partners

• Flexibility to access equipment

• Simple to advanced dosage forms (suspension, softgelcapsules, multilayers tablets…)

• Your partner of choice for DP Development from Lead Candidate to PhIII.

Page 5: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Timothé FLENETETISENSE SASGilet DECRO

[email protected]

Page 6: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

ETISENSE

• Start-up Deeptech - Spin-off de l’Université de Grenoble

• Spécialisée dans le développement de solutions de monitoring

physiologique non invasives et connectées

• 1er produit dédié au petit animal co-développé avec Sanofi R&D

• Brevet sur la mesure non invasive du Débit Cardiaque

Page 7: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Solution tout-en-un permettantle suivi de 3 fonctions

essentielles : cardiaque, respiratoire et activité

Sans chirurgie, sans contrainte de l’animal

Gilet breveté avec capteursintégrés + Logiciels d’analysede signaux utilisant des algorithmes d’IA

1er gilet Bluetooth avec pour petits animaux de laboratoire(rats, cochons d’inde, lapin)

Page 8: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

5 points clés à retenir• La télémétrie par gilet reconnue comme alternative aux techniques

invasives pour les études précliniques :

• Améliorer la qualité des données physiologiques in vivo en limitant le stress des animaux

• Combiner des études safety-pharmaco et toxicologie avec une solution Tout-En-1

• Economiser du temps et des moyens avec une solution simple et rapide à mettre en place

• Disponible aujourd’hui chez le rat

• Ouverts à partenariats pour d’autres espèces

Page 9: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Jean VIALLETCEO/CSOEarly in vivo preclinical studies

+33 476 549 51238700 La [email protected]

Page 10: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Efficacy

Evaluation

Target

Validation

Toxicity

Evaluation

Multi-CancerScreening

A UNIQUE IN VIVO ASSAY PLATFORMFOR YOUR ONCOLOGY DRUG CANDIDATES

• >350 studies for customers since 4 years

• >20,000 human xenografts in 2018

• Strong focus in Europe, US/Canada & Japan

• US Office in Boston/Cambridge

• Our customers:

o Academic Labs (42%)o Biotech (38%)o Mid-Size & Big Pharma (20%)

Page 11: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

The chicken embryo model

• 45 cancer models

• 17 cancer types

• New models every month

• PDX/CDX models

We also have set up dozens assays with modified cell lines for our customers.

Page 12: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Key points

Page 13: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Nathalie SOMKEEN EYE TechnologiesKEEN EYE Platform™ / Limitless custom algorithms for your specific (pre)clinical studies

+33 (0)1 53 46 27 01+33 (0)6 37 08 86 [email protected]

Page 14: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

KEEN EYE Technologies● We are a french health tech company developing innovative artificial intelligence

(AI) technologies for the Life Sciences

● Our goal is to support drug and biomarkers discovery and clinical diagnostics by putting the power of AI in the hands of medical professionals

● We are building the most advanced Machine Learning tool for Medical Imaging

analysis

● Our clients includes Biotechs, CROs and academics.

Page 15: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

KEEN EYE platform™● Based on our patented technology, you can access on-demand to your custom

algorithm(s) to quantify and discover biomarkers in your (pre)clinical Biomedical images.

© Keen Eye Technologies 2019

Studies

Platform™

Upload images

View analysis &

create reports

Internal

Collaborators

Scalable

environment

Real time

collaborative

system

View

Annotate

Analyse

External Collaborators

Share

Page 16: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

5 key points • Suited to any type of images (pathology, radiology, etc.) and any therapeutic

areas

• Easy-to-use and scalable user experiences

• Capabilities to support multiplex data analysis in medical images

• Explainable AI gives transparency to image features contributing to clinical

outcomes

• Regulatory compliant solutions

GLP ready*

for Pre-Clinical

Research

(EU)GDPR ready

IVD ready

Page 17: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Sofiane BELAIDLinkiLabCréée en janvier 2019Plateforme digitale de mise en relation d’acteurs scientifiques et techniques

06.25.82.55.63Villeurbanne (69100)[email protected]

Page 18: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

LinkiLab

Sofiane BELAID Samir BEGHDADI

Président Directeur Commercial

32 ans et Docteur-

Ingénieur en matériaux

innovants

Mes atouts

• Bonnes

connaissances du

monde de la R&D

• Management d’équipe

et de projet

• Réseaux dans le

domaine de la chimie

et des matériaux

33 ans et Ingénieur en

chimie

Mes atouts

• Bonne connaissance

des contrat de

partenariat

• Management d’équipe

• Connaissance des

techniques d’analyses

Sean BRYANS

Développeur Web

31 ans et développeur

web et application

Mes atouts

• Bonne connaissance

de plusieurs langages

informatiques

• Marketing en ligne

• Réseaux sociaux

Page 19: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

LinkiLabAvec LinkiLab, vous trouvez le bon prestataire en un clic !

Microscope

Je soumets ma demande

dans la plateforme

LinkiLab

Ma demande

est transmise à tous les

organismes enregistrés et

ayant un microscope.

A

B

C

Le client choisit librement son prestataire selon le coût, le délai, les avis,…et le note à son tour!

Page 20: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

5 points clés à retenir

Page 21: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Je vous remercie pour

votre attention!

www.linkilab.fr

Page 22: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Christophe DINIOROXCELL

3D Human reconstructedmodel of Small Intestine to evaluate formulations performance

+33 1 41 83 72 [email protected]

Page 23: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

OROXCELLCRO & PARTNESHIP BASED COMPANY :

❖PHARMA – FOOD HEALTH❖ DERMATO COSMETIC - MEDICAL DEVICE

❖15 years

❖ADME, TOX, Efficacy❖Screening to GLP compliant

Page 24: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

In Vitro Biopharmaceutical tool

0,0E+00

5,0E-06

1,0E-05

1,5E-05

2,0E-05

2,5E-05

3,0E-05

3,5E-05

4,0E-05

Pap

p c

m.s

-1

5 drug formulations tested in permeabilityAccross 3D Intestine

1- Drug Absorption in Human = f (formulation):

2- Improve Prediction of Oral Bioavailability : F= FA*FG*FH

Page 25: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

BCS Biowaiver for Drug Product/Generics

PropranololCaffeine

Metoprolol

SulfadiazineTolbutamide

Atenolol

Famotidine

ChlorothiazideXamoterol

GanciclovirAmdinocillin

Amiloride

Adult Formulationcapsule of 175 mg

Paediatric formulation

Sachet QSP 175 mg

0

20

40

60

80

100

-7 -6 -5 -4

Hu

man

dru

g a

bso

rbed

fra

ctio

n (

%)

Log Papp

Human Drug Fraction Absorbed % vs Papp in 3D Intestinal model

3- TEST BIOEQUIVALENCE OF DRUG PRODUCTS

Page 26: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Patrick Larcier, Pharm.D., MBA,PharmaLex arcDevelopment Consulting, Vigilance and Regulatory Affairs

+33 (0) 1 47 59 87 87Neuilly sur [email protected]

Page 27: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Supporting innovative products to towards Market Authorization.

Outsourcing of portfolio maintenance based on experienced and scalable resources

Both solutions offer services in a modular approach spanning your products needs through the entire lifecycle.

your partner for all services related to health agency obligations and legal requirements

Page 28: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Pre-investment

Asset evaluation & de-riskingplan definition (from both regulatory / access perspectives)

Asset profiling & strategic positioning

Biotech mapping, portfolio and / or asset analysis/ company capability assessment

Post-investment

Internal capabilities building / interim management / board membership

Regulatory strategy support and Due Diligence

Clinical /Safety strategy support

Market access / Pricing strategysupport and Due Diligence

Specific Offer to Biotechs & LS Investors

@ all investment & Life-Cycle stages

Expertise at key value check points (Regulatory /clinical & access strategic insights & operational support)

During investment

Corporate decisions(IPO, fundraising, partnering decision, patenting orientations, platform development decisions…)

Page 29: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

in 5 key points

• Local presence but International reach

• Recognized development expertise in various products (NCEs, Classical &

Complex biologics, vaccines, medical devices…)

• Assess, de-risking and leverage from a combined perspective (scientific,

regulatory & HTA / payers view point)

• Strong network of partners (incl. AFSSI members)

• Reactivity and flexibility

• ISO 9001:2015 certified and Accredited CIR (2016-2019)

Page 30: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Gilbert SKORSKIPHYLOGENEServices and RetD in genomics,

transcriptomics, proteomics, metabolomics, bioinformatics. +33466047799Bernis [email protected]

Votre LOGO

Page 31: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Routine labs:

Strong competition,

Small margins

Research labs:

High technicity,

High costs

PHYLOGENE:

High technicity and customized costs

GENOMICS

TRANSCRIPTOMICS

PROTEOMICS

METABOLOMICS

PCR, qPCR

Sequencing,

NGS

RT-qPCR,

RNAseq, ELISA

nanoLC-MS/MS

BIOINFORMATICSCORAVALIDTM

HolXploreTM

PHYLOGENE

ISO17025 COFRAC accreditated

Page 32: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Microbiota analysis expertise• Follow-up by quantitative PCRs of major species or genus, for example Staphylococcus sp. (Firmicutes),

Gives an answer such as « The product has/does not have an effect on tested genus » .

Time to delivery : 2 weeks

• Metagenomics comparative study of microbiome by NGSequencing 16S rDNAand/or ITS.

Gives answer in a report as : « The product/treatment does or does not impact the semi-quantitative composition and microbiome diversity».

Time to delivery : 10 weeks

• Metaproteomics comparative study of microbiome by relative quantification LC-MS/MS « shotgunproteomics » and bioinformatics/biostatistics dedicated data processing and analysis for microbiome :HolXploreTM

Gives answer in a report as : “ Effects of the product on functions and interactions of host and microbiome simultaneously ”

Time to delivery : 8-12 weeks for LC-MS/MS, 5 weeks for HolXploreTM

• Metabolomics in targeted way to sustain and confirm Metaproteomics

Page 33: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Keep in mind:• We love to listen and support our

customers to make them win. • We deliver innovative services

with customized prices and on time.

• Omics is set to become an increasingly important issue in the years ahead for life sciences.

• Proteomics, PTMs and metabolomics are the next steps

Same genome but different proteomes

Page 34: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Julien HugonProvepharm Life SolutionsLaboratoire Pharmaceutique & Prestataire de services

06 20 24 68 [email protected]

Page 35: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

PROVEPHARM LIFE SOLUTIONS• Fondé en 1998

• +35M€ de chiffre d’affaires

• +55 collaborateurs

• 5 produits sur le marché

• 2 laboratoires non GMP/pilotes

GMP petites molécules et

peptides

• Marchés stratégiques

• Colorants médicaux

• Médecine d’urgence

• Immunotherapies

• Maladies rares & orphelines

Page 36: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Ce que nous recherchons

• Des opportunités de partenariats

• M&A/licensing/co-développement/prestations de service

• Dans nos marchés stratégiques

• Colorants médicaux

• Médecine d’urgence

• Immunotherapies

• Maladies rares & orphelines

Page 37: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

4 points clés à retenir

• Laboratoire pharmaceutique indépendant

• A forte croissance

• A taille humaine

• En recherche de partenariat dans des marchés ciblés

Page 38: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Patrice ROOLROOWINVotre partenaire CMC

Tél. : +33 (0)6 61 95 34 50Ville : Riom (63)E-mail : [email protected]

Page 39: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

ROOWIN• 25 collaborateurs dont 23 scientifiques hautement qualifiés

• Equipements de premiers plans (Merck MSD) – 1600 m2

• CDMO dans le domaine de la chimie fine « small molecules »

• Quelques références de produits développés à partir du « Lead »

• Elafibranor® (GFT505) – GENFIT (France) – Phase 2a puis transfert à Seqens

• ABX464 – Abivax (France) – Phase 2a puis transfert à Seqens

• TK216 – Oncternal (USA San Diego) – Phase 1/2

Page 40: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

NOS SERVICES

• Drug discovery – Synthèse de nouvelles molécules/impuretés

• Développement de procédés

• Synthèse GMP

• Développement/validation de méthodes analytiques/Etudes

de stabilités

• Rédaction dossier règlementaire : IMPD/IND/DMF

Page 41: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

VOTRE ACCELERATEUR CMC

• Prestation intégrée de la partie CMC – 1 seul partenaire

• Protection de l’IP

• Pas de problèmes d’interfaces à gérer

• Gain de temps par l’absence de sélection de divers partenaires

• Efficience par la capitalisation de la connaissance dès le début du projet

• Qualité reconnue depuis 22 ans

Page 42: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Where machine learning, chemistry and biology meet

Guillaume BOLLOT, PhD, CSOMob. 06 78 08 51 32

[email protected]

Genopole Entreprises4, rue Pierre Fontaine

Evry

Laboratory SABNPUniversité d’Evry

Lab. 01 69 47 01 76

Page 43: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

6 employees : molecular modeling / artificial intelligence / experimental

2013 Sales revenues 900 k€ CA

They trust us

They support us

Page 44: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Insight of computational tools for compound discovery

Page 45: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

To remember

• High expertise

• Cloud computing facilities

• Programming skills

• Protein-Protein interaction platform

• Engaged

Agrément CIR

Page 46: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Bruno Tillier, CEOSynthelisProduction de protéines par système acellulaire (cell-free)

06 11 19 21 47Grenoble - La [email protected]

Page 47: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Synthelis

• Une équipe

• Une technologie propriétaire

• + 90% de succès d’expression, 85% de protéines actives

• Des services pour nos clients:

• + 70 clients: pharma, biotech et académiques

Page 48: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Technologie de bioproduction cell-free

• Système cell-free optimisé (coûts et performance) prêt à être

industrialisé.

Page 49: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

5 points clés à retenir

Technologie de rupture pour révolutionner la bioproduction

Rapide pour réduire le « Time to Clinic » et « Time to Market »

Flexible pour réduire le « Footprint » et s’adapter aux besoins

Performante pour améliorer drastiquement les rendements

Economique

Page 50: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Murielle DORSOUNITHER DEVELOPPEMENT BORDEAUX

Mob: +33 6 13 79 19 59Le Haillan (33)[email protected]

Page 51: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

CHINAWuhan

USARochester, NY

BRAZILBarretosSao Paulo

FRANCEAmiensBordeauxColomiersCoutancesGannat Paris

Production Commercial Office Innovation & development

GLOBAL ORGANIZATION

Page 52: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

• Filiale du groupe UNITHER PHARMACEUTICALS, CDMO

• Leader Mondial sur la technologie Blow-Fill-Seal (BFS) et pionnier pour les sticks liquides notamment

• UDB en quelques mots

• Centre d’excellence en développement pharmaceutique (analytique et galénique)

• Plus de 25 ans d’expérience

• Etablissement pharmaceutique aux normes BPF autorisé par l’ANSM & ANSES

UNITHER DEVELOPPEMENT BORDEAUX

Page 53: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

UNITHER DEVELOPPEMENT BORDEAUX

Plant

1800 m250 PersonsEuropean GMP

Page 54: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

READY-TO-USE - ORAL DOSAGE FORMS

ODtech® est une plateforme multiservice offrant des technologies galeniquesinnovantes et notamment par les formes orales, en unidose et prêtes-à-l’emploi, facilitant l’observance du patient.

*y compris les formulations transmuqueuses par voie buccale

54

Orodispersible

Stick-Pack Poudre

100mg<<1000mg

MELANGE ORO-DISPERSIBLE

AVEC / SANS

particules fonctionnalisées

Orodispersible

Stick-Pack liquid*

> 1000mg

AVEC / SANS

particules fonctionnalisées

Orodispersible

Comprimé

< 100mg

COMPRIME ORO-DISPERSIBLE

AVEC / SANS

particules fonctionnalisées

Page 55: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

5 points clés à retenir

• Une solution centrée sur le benefice patient:

• La moitié de la population rencontre des difficultés dans la prise des traitements par voie orale (Population gériatrique et pédiatrique notamment)*

• Une solution technologique différenciante

• Une expertise en formulation – formes conventionnelles et innovantes

• Une technologie pouvant être adaptée à différents types de principes actifs

• Un process continu sur 1 seul site

FormulationDéveloppement pharmaceutique

Support Annalytique

Etudes de stabilité ICH

Support au transfert industriel

Page 56: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

Yolande MisseriUROSPHEREUrolead, a new platform for preclinical uro-oncology

+33 (0)561 555 [email protected]

Votre LOGO

Page 57: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

UROSPHERE

• Research company founded in 2004, certified ISO9001:2015

• Specialized in preclinical models in Urogenital diseases

• Focused from functional urology, inflammation and pain to cancer

• Large network of clinics and hospitals to obtain human tissues

• More than 300 compounds tested for >100 companies

Page 58: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Urolead: an integrated platform from cells to human tumors

Page 59: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

5 key points to keep in mind

• A unique platform dedicated to preclinical uro-oncology

• A unique biobank of patient-derived-xenografts

• From PoC to full preclinical development

• Flexibility/ adaptability/ customized studies

• A highly-skilled team associated to a network of experts

Page 60: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

2 minutes pour convaincre

IVOSEV VladimirVectorBuilder GmbH

+33781174643Valence, [email protected]

Page 61: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

VectorBuilder

Page 62: Sébastien JACQUET, PhD Delpharm Development Early ...€¦ · KEEN EYE Technologies We are a french health tech company developing innovative artificial intelligence (AI) technologies

Points clés à retenir