WelcomeWelcome! We are thrilled to have you join us in Philadelphia today for Zoobiquity Conference 6. Experts in human and veterinary medicine, like yourself, are confronted with similar clinical challenges and shared diagnoses and this conference is designed to foster conversations and collaborations that can lead to new ways to diagnose, model, and treat diseases in all species. We are confident that you will leave this event with an increased awareness of and appreciation for the interconnectivity of health and medicine in animals and humans. Please take time throughout the day to talk with other practitioners and students, build bridges, and learn from each other. Though species may be different, our similarities far outweigh our differences and opening ourselves up to this can create excellent opportunities and improved health for animals and humans alike.

Continuing Veterinary Education CreditUp to 6.00 hours of continuing education credit are available for veterinarians and certified veterinary technicians through the Pennsylvania Veterinary Medical Association (PVMA). PVMA is an accredited provider of continuing education credit by the Pennsylvania State Board of Veterinary Medicine and the New York State Education Department.

Continuing Medical Education CreditThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of the Pennsylvania Medical Society and Pennsylvania Veterinary Medical Association. The Pennsylvania Medical Society is accredited by the ACCME to provide continuing medical education for physicians. The Pennsylvania Medical Society designates this live activity for a maximum of 6.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Faculty and all others who have the ability to control the content of continuing medical education activities sponsored by the Pennsylvania Medical Society are expected to disclose to the audience whether they do or do not have any real or apparent conflict(s) of interest or other relationships related to the content of their presentations.

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Saturday, April 2, 2016

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CME DisclosureThe following faculty members have disclosed that they have relevant financial relationships:

Faculty Name Company Name Nature of Relationship

Elizabeth Grice, PhD Jasnssen Research & Development Research Grant GOJO Industries Consultant

Kristy Weber, MD Roche Clinical Trial

None of the other planners and faculty have any relevant financial relationships to disclose.

Conference EvaluationA conference evaluation will be emailed to all participants following the conference. Physicians wishing to receive Category 1 credit must com-plete and sign the printed evaluation form in their registration packet and return it to the Zoobiquity registration desk by the conclusion of the event.

Badges Name badges are color coded as follows:

• Red Physicians and Medical Students

• Blue Veterinarians and Veterinary Students

• Orange Nurses and Nursing Students

• Yellow Certified Veterinary Technicians and Veterinary Assistants

• Green Allied Human Health Professionals

• Black Other/Non-Clinicians

• Clear Volunteers and Staff

Special Thanks!Special thanks to the Philadelphia Zoo

for providing one complimentary ticket to the zoo for each Zoobiquity Conference 6 registrant. Please stop by the Zoobiquity registration desk

anytime today to pick up your ticket.

Meet the Authors of Zoobiquity!Zoobiquity: The Astonishing Connection Between Human and Ani-mal Health

Books will be available for purchase during the morning sessions and the closing reception. Dr. Natterson-Horowitz and Kathryn Bowers will sign book copies during the reception beginning at 5:30pm.

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SPECIAL THANKS TO OUR GENEROUS SPONSORS

Schedule of Events—Saturday, April 2, 20167:00 – 7:50am Registration and Continental Breakfast

7:50 – 8:00am Welcome and Opening Remarks—Dr. Barbara Natterson-Horowitz, Professor of Medicine, UCLA Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles

8:00 – 8:25am Keynote Speaker: Comparative Medicine: Challenges and Opportunities—Dr. Stephanie Murphy, Director, Division of Comparative Medicine, National Institutes of Health

8:30 – 9:30am Case Presentation 1—Atopic Dermatitis and the Cutaneous Microbiome

9:40 – 10:40am Case Presentation 2—Sleep Apnea Causes and Pharmacotherapies

10:40 – 11:05am Break

11:00am – 12:00pm Case Presentation 3—Osteosarcoma Immunotherapy

12:00 – 12:30pm Closing Remarks; Instructions for Lunch and Rounds—Dr. Barbara Natterson-Horowitz

12:30 – 12:40pm Break into Groups for Rounds, Distribute Boxed Lunches

12:40 – 12:45pm Board Buses and Depart for Offsite Rounds Locations

1:30 – 4:30pm Afternoon Rounds at Hill Pavilion and Philadelphia Zoo

2:00 – 4:15pm Afternoon Rounds at New Bolton Center

4:30 – 5:15pm Buses Return from Philadelphia Zoo

4:15 – 5:30pm Buses Return from New Bolton Center

5:30 – 7:00pm Closing Reception at Smilow Center for Translational Medicine

Final Remarks—The Honorable Russell Redding, Secretary, Pennsylvania Department of Agriculture

MORNING SESSIONS—8:30AM–12:30PM

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ARTHUR H. RUBENSTEIN AUDITORIUM SMILOW CENTER FOR TRANSLATIONAL RESEARCH

Atopic Dermatitis and the Cutaneous Microbiome—8:30–9:30amFACULTY:• Elizabeth Grice, PhD, Assistant Professor, Department of Dermatology,

Perelman School of Medicine, University of Pennsylvania• Charles Bradley, VMD, Lecturer, Department of Pathobiology, School of

Veterinary Medicine, University of Pennsylvania• Jennifer Gardner, MD, Assistant Professor of Dermatology, University of

Washington, School of Medicine

CASES:• Atopic dermatitis with secondary staphylococcal folliculitis in a

three-year-old female spayed French bulldog • Atopic dermatitis with secondary cutaneous staphylococcal overgrowth in a three-year-old girl

Sleep Apnea Causes and Pharmacotherapies—9:40–10:40amFACULTY:• Joan Hendricks, VMD, PhD, the Gilbert S. Kahn Dean, School of Veterinary

Medicine, University of Pennsylvania • Sigrid Veasey, MD, PhD, Professor, Department of Medicine, Perelman

School of Medicine, University of Pennsylvania

CASES:• Restless sleep and daytime hypersomnolence in a two-year-old male

English bulldog• Hypersomnolence, loud snoring, and obesity in a 40-year-old man

Osteosarcoma Immunotherapy—11:00am–12:00pmFACULTY:• Nicola Mason, BVetMed, PhD, Associate Professor of Medicine and

Pathobiology, School of Veterinary Medicine, University of Pennsylvania• Kristy Weber, MD, Professor, Department of Orthopaedic Surgery; Director

of the Sarcoma Program, Abramson Cancer Center; Chief of Orthopaedic Oncology, Perelman Center For Advanced Medicine

CASES:• Induction and effect of anti-tumor immunity in a nine-year-old male

castrated Labrador Retriever with osteosarcoma• Left distal femoral osteosarcoma with eventual metastatic disease to the

lung in an eight-year-old boy

Affective Aggression and ImpulsivityFACULTY:• CarloSiracusa,DVM,PhD,ClinicalAssistantProfessorofAnimalBehavior,

SchoolofVeterinaryMedicine,UniversityofPennsylvania• StephanieDeutsch,MD,ChildAbusePediatricsFellow,TheChildren’s

HospitalofPhiladelphia

CASES:• Recurrent,affectiveaggressionbetweentwofemale,mixed-breed

householddogs• Recurrent,intra-familialperpetrationofintimatepartnerviolence

Cleft Lip and PalateFACULTY:• MariaSoltero-Rivera,DVM,AdjunctAssistantProfessorofDentistryand

OralSurgery,SchoolofVeterinaryMedicine,UniversityofPennsylvania• JesseTaylor,MD,AttendingSurgeon,DivisionofPlasticand

ReconstructiveSurgery,Co-DirectoroftheCleftLipandPalateProgram,TheChildren’sHospitalofPhiladelphia

CASES:• Secondarycleftpalaterepairinajuveniledog• Cleftlipandpalaterepairinateenagepatient

Self Injury: Feather Plucking Behavior in Parrots and TrichotillomaniaFACULTY:• La’ToyaLatney,DVM,ServiceHead,ExoticCompanionAnimalMedicine,

SchoolofVeterinaryMedicine,UniversityofPennsylvania• MartinFranklin,PhD,AssociateProfessorofClinicalPsychologyinPsy-

chiatry;Director,ChildandAdolescentOCD,Tics,Trichotillomania,andAnxietyGroup(COTTAGe),PerelmanSchoolofMedicine,UniversityofPennsylvania

CASES:• 14-year-oldmaleintactAfricangreyparrotwithchronicfeather-picking

disorder• Trichotillomaniainaperson

HILLPAVILIONSCHOOLOFVETERINARYMEDICINE

AFTERNOON ROUNDS—1:30–4:30PM

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Atrial FibrillationFACULTY:• JoAnnSlack,DVM,AssociateProfessorofLargeAnimalCardiologyand

Ultrasound,SchoolofVeterinaryMedicine,UniversityofPennsylvania• RobertD.Schaller,DO,AssistantProfessorofClinicalMedicine,

PerelmanSchoolofMedicine,UniversityofPennsylvania

CASES:• Chronicatrialfibrillationinanupperlevelperformancehorse• Atrialfibrillationinaperson

Obesity and Aggression: The Dilemma of Fat and Happy vs. Lean and MeanFACULTY:• TomParsons,VMD,PhD,AssociateProfessorofSwineProduction

Medicine,SchoolofVeterinaryMedicine,UniversityofPennsylvania• TanjaKral,AssociateProfessorofNutritionalSciences,Schoolof

Nursing,UniversityofPennsylvania

CASES:• Managingnutritionalandbehavioralneedsofdomesticatedpigswhen

housedingroups• Cognitive,sensory,andnutritionalcontrolsofappetiteandeatingin

childrenandadultsandtheirrelevancetoobesity

Tour of New Bolton CenterLocatedon700acresinChesterCounty,Pennsylvania,PennVet’sNewBoltonCenteristheUniversityofPennsylvania,SchoolofVeterinaryMedi-cine’slargeanimalhospitalandcampus.NewBoltonCenterhospitalhan-dlesmorethan4,000patientvisitsperyear,whileitsfieldserviceveterinar-ianstreatmorethan37,000patientsonlocalfarms.NewBoltonCenterisaleaderinveterinarymedicine,rangingfromprimarycarethroughthemostcomplicatedandsophisticatedmedicalandsurgicaltechniques.Cliniciansareboard-certifiedinspecialtiesincludinglargeanimalinternalmedicine,cardiology,neurology,ophthalmology,reproduction,sportsmedicine,surgery,andemergencyandcriticalcare.Knownforitspioneeringworkindiagnosticimaging,NewBoltonCenterrecentlyinstalledandisdevelopingprotocolsforarevolutionaryrobotics-controlledimagingsystemforuseinthestandingandmovinghorse.Aleaderinorthopedicsurgery,NewBoltonCenterhasapoolrecoverysystemforhorsesawakingfromanesthesiaaftercomplexfracturerepairsurgeries.Thehospitalfeaturesastate-of-the-art,biosecurecriticalcarecenter,dividedtoaccommodatecolicpatientsononesideandpatientsbeingtreatedforinfectiousdiseasesontheother.NewBoltonCenter’scampusalsoincludesextensivediagnosticandresearchlaboratories,aswellasaswinecenter,aworkingdairy,andapoultryunitthatprovidevaluableresearchfortheagricultureindustry.TheMarshakDairyhas180milkingcows,whichproduceatotalof1,500gallonsofmilkperday.TheSwineTeachingandResearchCenter,homefor200sowsandtheirpiglets,featuresanopenhousingmodelthatallowssowsmorefreedomofmovementthantraditionalgestationstalls.

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NEWBOLTONCENTERSCHOOLOFVETERINARYMEDICINE

AFTERNOON ROUNDS—2:00–4:15PM

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PHILADELPHIAZOO

AFTERNOON ROUNDS—1:30–4:30PM

Great Ape Cardiology and Management of Cardiac DiseaseFACULTY:• TimGeoroff,VMD,AssociateVeterinarian,PhiladelphiaZoo• GreggPressman,MD,AssociateDirector,CardiovascularDiseases

FellowshipProgram;AssociateDirector,EchocardiographyLaboratory,EinsteinMedicalCenter

CASES:• Managementofcardiomyopathyina30-year-oldadultmalesilver-

backwesternlowlandgorilla• Managementofcardiomyopathyandcongestiveheartfailureina

57-year-oldmaleadulthuman

Severe Enteritis in a Pediatric PatientFACULTY:• KeithC.Hinshaw,DVM,DirectorofAnimalHealth,PhiladelphiaZoo• LouisM.Bell,MD,ChiefoftheDivisionofGeneralPediatrics,

TheChildren’sHospitalofPhiladelphia

CASES:• Severeenteritisandassociatedcomplicationsinan18-month-old

Coquerel’ssifaka(Propithecuscoquereli)• Severeenteritisandassociatedcomplicationsinafive-month-old

humaninfantwithbloodydiarrheaandseizures

Behavioral Variation in Response to Exposure to a Novel EnvironmentFACULTY:• MariekeC.Gartner,PhD,AnimalBehaviorandWell-Being

PostdoctoralResearchFellow,PhiladelphiaZoo• MargaretC.Souders,PhD,AssistantProfessorofHumanGenetics,

SchoolofNursing,UniversityofPennsylvania;PediatricNursePractitioner,DepartmentofChildandAdolescentPsychiatryandBehavioralSciences,TheChildren’sHospitalofPhiladelphia

CASES:• Behavioralchangesinanimalswithaccesstoanoveltrailsystem• Theeffectofnovelenvironmentsonnon-verbalchildren,particularly

thosediagnosedwithAutismSpectrumDisorder