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Safety Consideration Software limits on robot controller Limit switches on the robot “wrist” to prevent excess rotations Limit switches on the vertical travel Contact detection on upper arm of robot Enable button on hand pendant E-Stop button on hand controller Couch can lower for patient egress during power outage

Safety Consideration Software limits on robot controller Limit switches on the robot “wrist” to prevent excess rotations Limit switches on the vertical

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Safety Consideration

Software limits on robot controller Limit switches on the robot “wrist” to prevent excess

rotations Limit switches on the vertical travel Contact detection on upper arm of robot Enable button on hand pendant E-Stop button on hand controller Couch can lower for patient egress during power

outage

Case Study 2

Automated Motion Correction –

Tracking the Spine

Challenges of Spinal Treatments

The spine moves during treatment

Vertebrae can move independent of one

another

Rigid transformation is not valid in most

cases

Adjacent structures (spinal cord) necessitate

high precision and accuracy

Traditional Radiation Therapy

Difficult to adequately immobilize the patient, internal structures, & the target

Image guidance (IGRT) confirms treatment setup but no compensation for target movement during the treatment

Implanted markers can increase accuracy but introduce additional challenges Invasive Delays time-to-treatment

Non-invasively registers non-rigid and bony anatomy

landmarks

Internal markers or frames not required

Automatically tracks spine from DRR image pairs

Cervical, thoracic, lumbar and sacral

Sub-millimeter targeting accuracy, (0.52 +/- 0.22 mm)† ‡

† As measured in end-to-end testing. Reference: Muacevic, A., Staehler, M., Drexler, C., Wowra, B., Reiser, M. and Tonn, J. Technical description, phantom accuracy and clinical feasibility for fiducial-free frameless real-time image-guided spinal radiosurgery. J Neurosurgery Spine.‡ Xsight accuracy specification of .95 mm.

Spine Tracking

   

   

               

               

               

               

               

               

               

               

       

       

       

       

Step 3Step 2Step 1

How it Works…

Hierarchical Mesh Tracking

Identifies unique bony

structures

Enables registration of

non-rigid

skeletal

anatomy

Estimates local

displacements in

bony features

Live kV image

Image B

Image A

DRR (from CT) Displacement Field

How it Works…

Spine Tracking Animation

Case Study 3

Automated Motion Compensation –

Tracking Respriation

Respiratory Tracking

Challenges of respiratory motion

Respiratory-induced motion of

tumors causes significant

targeting uncertainty

• Lung, liver, and pancreas

Traditional radiation therapy

margins are not optimized for

high-dose radiosurgery

Traditional Radiation Therapy

Solutions for compensating for motion plagued with repeatability and compliance issues

Healthy tissues is unnecessarily treated

† Reference: Dieterich S, Taylor D, Chuang C, Wong K, Tang J, Kilby W, Main W. The CyberKnife Synchrony Respiratory Tracking System: Evaluation of Systematic Targeting Uncertainty. ‡Synchrony clinical accuracy specification of 1.5 mm for moving targets.

Respiratory Tracking

Tightly contoured beams following

tumor motion in real-time

Delivers throughout the respiratory

cycle without gating or breath-

holding

Instantly adapts to variations in

breathing patterns

Proven accuracy

Systemic error of 0.70 +/-

0.33mm† ‡

How It Works… (1)

Two features to form the basis for accuracy

Gold markers, implanted prior to treatment

LED markers on a special patient vest

How It Works… (2)

Prior to treatment start: creation of dynamic correlation model

Imaging system takes positions of markers at discrete points of time

LED’s are monitored in real time by a camera system

How It Works… (2)

Prior to treatment start: creation of dynamic correlation model

Markers are monitored in real time by a camera system

Imaging system takes positions of fiducials at discrete points of time

time

dis

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dis

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How It Works… (3)

This process repeats throughout the treatment, updating and correcting beam delivery based upon the patient’s current breathing pattern

time

dis

pla

cem

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dis

pla

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time

Synchrony Animation

Summary

There is a place for autonomous robotics in medicine

Special consideration must me taken to adapt to dynamic environment

Safety is most important requiring redundancy throughout

Greater demand for precision and accuracy will pave the way for future applications