Embed Size (px)
DESCRIPTION
S1292 Chelerythrine Chloride is a benzophenanthridine alkaloid extracted from the plant Greater celandine (Chelidonium majus). It is a potent, selective, and cell-permeable PKC inhibitor (IC50 = 660 nM). It has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects.M.Wt: 384.83Formula: C21H18NO4.HClSolubility: UnknownPurity: >99%Storage: at -20℃ 2 yeaBiological Activity of Chelerythrine Chloride:Chelerythrine is a benzophenanthridine alkaloid extracted from the plant Greater celandine (Chelidonium majus). It is a potent, selective, and cell-permeable PKC inhibitor (IC50 = 660 nM). It has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. [1,2]References on Chelerythrine Chloride:[1] http://en.wikipedia.org/wiki/Chelerythrine [2] Herbert JM et al. Biochem Biophys Res Commun. 1990 Nov 15;172(3):993-9
Citation preview
Product Information
Chelerythrine is a benzophenanthridine alkaloid extracted from the plant Greater celandine (Chelidonium majus). It is a potent, selective, and cell-permeable PKC inhibitor (IC50 = 660 nM). It has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. [1,2]
Biological Activity
[1] http://en.wikipedia.org/wiki/Chelerythrine
[2] Herbert JM et al. Biochem Biophys Res Commun. 1990 Nov 15;172(3):993-9
References
Novel Kinase Inhibitors for cell signaling & oncology research
S1292 Chelerythrine Chloride
Technical Data:M.Wt:Formula:Solubility:Purity:Storage:CAS No.:
384.83C21H18NO4.HClUnknown99%at -20℃ 2 years34316-15-9
Notes
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
Please inspect packages immediately upon
receipt and notify customer service within
3 days of delivery of any damage or
discrepancies.Our team will take quick and
appropriate action to correct any problem.
Goods ordered in error can only be accepted
for return if made within 3 days of delivery,
are unopened,have been stored correctly and
are in good condition. Should you wish to
return any item(s), prior authorization must
be received from our customer service team.
Returns accepted will be subject to a 30%
restocking charge.
For all product returns and product replace-
ments,please contact Selleck directly by
+1-713-922-4115.
Please have on hand, the invoice number,
purchase order number,air bill number and
approximate date of shipment/receipt.
Fax: +1-713-796-9816
Toll Free: (877)796-6397-- USA and Canada only --
© Copyright 2010 Selleck chemicals.
Orders+1-713-922-4115
Webwww.selleckchem.com
Tech [email protected](chemistry support)
[email protected](bio support)
Please visit www.selleckchem.com to download MSDS and CoA.
MSDS & CoA
Return Policy
Selleck Overnight Delivery Service
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleckchem products, stored under
the recommended conditions, are stable for two year. Products are sometimes shipped at a temperature that differs from the recommended
storage temperature,most are recommended stored at -20 .Many products are stable in the short-term at temperatures that differ from that
required for long-term storage. We ensure that the product is shipped under conditions that will maintain the quality of the product, but save
you shipping charges by using the most economical storage conditons for an overnight shipment. Upon receipt of the product, follow the storage
recommendations on the product data sheet.
℃
N+Me
O
O
O
O Cl -
![Paroxetine suppresses recombinant human P2X7 responses · KN-62 [19], calmidazolium [20], chelerythrine [21], a tyrosine kinase inhibitor [22], SB203580 [23], DIDS [24], clemastine](https://img.pdfslide.us/doc/110x75/5f3666be62cca735e15dfa9e/paroxetine-suppresses-recombinant-human-p2x7-responses-kn-62-19-calmidazolium.jpg)
