Product Information

Posaconazole is a triazole antifungal drug. Posaconazole works by disrupting the close packing of acyl chains of phospholipids, impairing the functions of certain membrane-bound enzyme systems such as ATPase and enzymes of the electron transport system and thus inhibiting growth of the fungi. It does this by blocking the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors. Posaconazole is significantly more potent at inhibiting 14-alpha demethylase than itraconazole. [1]

Biological Activity

[1] http://en.wikipedia.org/wiki/Posaconazole

[2] http://www.rxlist.com/noxafil-drug.htm

References

Novel Kinase Inhibitors for cell signaling & oncology research

S1257 Posaconazole

Technical Data:M.Wt:Formula:Solubility:Purity:Storage:CAS No.:

700.78C37H42F2N8O4

Unknown99%at -20℃ 2 years171228-49-2

Notes

NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.

Please inspect packages immediately upon

receipt and notify customer service within

3 days of delivery of any damage or

discrepancies.Our team will take quick and

appropriate action to correct any problem.

Goods ordered in error can only be accepted

for return if made within 3 days of delivery,

are unopened,have been stored correctly and

are in good condition. Should you wish to

return any item(s), prior authorization must

be received from our customer service team.

Returns accepted will be subject to a 30%

restocking charge.

For all product returns and product replace-

ments,please contact Selleck directly by

info@selleckchem.com or

+1-713-922-4115.

Please have on hand, the invoice number,

purchase order number,air bill number and

approximate date of shipment/receipt.

Fax: +1-713-796-9816

Toll Free: (877)796-6397-- USA and Canada only --

© Copyright 2010 Selleck chemicals.

Orders+1-713-922-4115

enquiry@selleckchem.com

Webwww.selleckchem.com

Tech Supporttech@selleckchem.com(chemistry support)

techbio@selleckchem.com(bio support)

Please visit www.selleckchem.com to download MSDS and CoA.

MSDS & CoA

Return Policy

Selleck Overnight Delivery Service

Specific storage and handling information for each product is indicated on the product datasheet. Most Selleckchem products, stored under

the recommended conditions, are stable for two year. Products are sometimes shipped at a temperature that differs from the recommended

storage temperature,most are recommended stored at -20 .Many products are stable in the short-term at temperatures that differ from that

required for long-term storage. We ensure that the product is shipped under conditions that will maintain the quality of the product, but save

you shipping charges by using the most economical storage conditons for an overnight shipment. Upon receipt of the product, follow the storage

recommendations on the product data sheet.

℃

Synonyms: Noxafil

N N O O

FF

NN

N

NN

N

O

HO