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www.labortechnik.com Page 1/2 LTF Labortechnik GmbH & Co. KG • Hattnauer Straße 18 • D-88142 Wasserburg/Bodensee • Tel. +49 (0) 83 82 / 98 52-0 • Fax +49 (0) 83 82 / 98 52-32 [email protected] • www.labortechnik.com LG_088_E 06/2018 Subject to technical changes and errors. Software Real–Time cell growth logging 3D graphical representaon of OD or growth rate over me over unit ● Pause opon ● Save/Load opon ● Report opon: PDF and Excel ● Connect up to 12 units (recommended) simultaneously to 1 computer ● Remote monitoring opon (requires internet connecon) ● Cycling/Profiling opons ● User manual calibraon possibility for most cells RTS-8 is a personal bioreactor that ulizes patented Re- verseSpin® technology that applies non-invasive, mecha- nically driven, low energy consumpon, innovave type of agitaon where cell suspension is mixed by the single- use falcon bioreactor tube rotaon around its axis with a change of direcon of rotaon moon resulng in highly efficient mixing and oxygenaon for aerobic culvaon. Combined with a nearinfrared opcal system it is possible to register cell growth kinecs non-invasively in real me. Features ● Parallel culvaon enables to save me and resources for bioprocess opmizaon ● Individually controlled bioreactor accelerates opmizaon process ● Possibility to culvate microaerophilic and obligate anaerobic microorganisms (not strict anaerobic condions) ● Reverse–Spin® mixing principle enables non-invasive biomass measurement in real me ● Near-infrared opcal system makes it possible to register cell growth kinecs ● Free of charge soſtware for storage, demonstraon and analysis of data in real me ● Compact design with low profile and small footprint for personal applicaon ● Temperature control for bioprocess applicaons ● Acve cooling for rapid temperature control, e.g. for temperature fluctuaon experiments ● Task profiling for process automazaon ● Cloud data storage to remotely monitor the process of culvaon while at home or using a mobile phones RTS-8 Multi-channel Bioreactor With real time biomass, pH and pO 2 measurement Benefits RTS mixing principle has a number of advantages, e.g. automac balancing, defoaming single-use, etc., but one of the more important points is that, due to the individual rotaon principle and thermostang of each bioreactor tube, different condions for supporng the temperature (from 4 to 70°C) and aeraon condions can be applied (from anaerobic to aerobic). Applications ● Fermentaon real me growth kinecs ● Clone candidate screening ● Protein expression ● Temperature stress and fluctuaon experiments ● Media screening and opmizaon ● Growth characterizaon ● Inhibion and toxicity tests ● Strain quality control

RTS-8 Multi-channel Bioreactor - Labortechnik

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Page 1: RTS-8 Multi-channel Bioreactor - Labortechnik

www.labortechnik.com

Page 1/2

LTF Labortechnik GmbH & Co. KG • Hattnauer Straße 18 • D-88142 Wasserburg/Bodensee • Tel. +49 (0) 83 82 / 98 52-0 • Fax +49 (0) 83 82 / 98 [email protected] • www.labortechnik.com

LG_0

88_E

06/

2018

S

ubje

ct to

tech

nica

l cha

nges

and

err

ors.

Software● Real–Time cell growth logging● 3D graphical representati on of OD or growth rate over ti me over unit● Pause opti on● Save/Load opti on● Report opti on: PDF and Excel● Connect up to 12 units (recommended) simultaneously to 1 computer● Remote monitoring opti on (requires internet connecti on)● Cycling/Profi ling opti ons● User manual calibrati on possibility for most cells

RTS-8 is a personal bioreactor that uti lizes patented Re-verseSpin® technology that applies non-invasive, mecha-nically driven, low energy consumpti on, innovati ve type of agitati on where cell suspension is mixed by the single-use falcon bioreactor tube rotati on around its axis with a change of directi on of rotati on moti on resulti ng in highly effi cient mixing and oxygenati on for aerobic culti vati on. Combined with a nearinfrared opti cal system it is possible to register cell growth kineti cs non-invasively in real ti me.

Features● Parallel culti vati on enables to save ti me and resources for bioprocess opti mizati on● Individually controlled bioreactor accelerates opti mizati on process● Possibility to culti vate microaerophilic and obligate anaerobic microorganisms (not strict anaerobic conditi ons)● Reverse–Spin® mixing principle enables non-invasive biomass measurement in real ti me● Near-infrared opti cal system makes it possible to register cell growth kineti cs ● Free of charge soft ware for storage, demonstrati on and analysis of data in real ti me● Compact design with low profi le and small footprint for personal applicati on ● Temperature control for bioprocess applicati ons● Acti ve cooling for rapid temperature control, e.g. for temperature fl uctuati on experiments● Task profi ling for process automati zati on● Cloud data storage to remotely monitor the process of culti vati on while at home or using a mobile phones

RTS-8 Multi-channel BioreactorWith real time biomass, pH and pO2 measurement

Benefi tsRTS mixing principle has a number of advantages, e.g. automati c balancing, defoaming single-use, etc., but one of the more important points is that, due to the individual rotati on principle and thermostati ng of each bioreactor tube, diff erent conditi ons for supporti ng the temperature (from 4 to 70°C) and aerati on conditi ons can be applied (from anaerobic to aerobic).

Applications● Fermentati on real ti me growth kineti cs● Clone candidate screening● Protein expression● Temperature stress and fl uctuati on experiments● Media screening and opti mizati on● Growth characterizati on● Inhibiti on and toxicity tests● Strain quality control

Page 2: RTS-8 Multi-channel Bioreactor - Labortechnik

LTF Labortechnik GmbH & Co. KG • Hattnauer Straße 18 • D-88142 Wasserburg/Bodensee • Tel. +49 (0) 83 82 / 98 52-0 • Fax +49 (0) 83 82 / 98 [email protected] • www.labortechnik.com

www.labortechnik.com

Page 2/2

Measurement range 0–100 OD600

Measurement wavelength (λ) 850 ± 15 nm

Light source Laser

Measurement periodicity per hour 1-60

Temperature setting range +4°C – +60°C

Temperature control range 15°C below ambient up to +60°C

Heating/coolling rate 0,5°C/min

Sample volume 3 – 50 ml

Speed control range 50 – 2700 rpm

Max. number of units connectedwith the software 12 (recommended)

Display LCD

Minimum PC requirements Intel/AMD Processor, 1 GB RAM, Windows XP* /Vista/7/8/8.1, 2.0 USB port

Optimal PC requirementsIntel/AMD Processor, 3 GB RAM Windows XP*/Vista/7/8/8.1/10,

USB 2.0 port *not guaranteed because OS not supported by producer

Dimensions (W×D×H) 330 x 580 x 320 mm

Weight 15 kg

Internal power supply Input AC 240 V 50/60 Hz; Output DC 12 V

O2 sensor

Range 0 – 100%

Accuracy ± 0.01% O2 at 0.21%, ± 0.1% O2 at 20.9%

Drift < 0.015% O2 per Day

Temperature range up to 40°C

pH sensor

Range pH 4.0 – pH 8.5

Accuracy ± 0.05 pH at pH 7 with onepoint calibration, ± 0.10 pH at pH 7 with precalibration

Drift < 0.005 pH per Day

Temperature range pH up to 40°C

Specification

RTS-8 Multi-channel BioreactorWith real time biomass, pH and pO2 measurement

LG_0

88_E

06/

2018

S

ubje

ct to

tech

nica

l cha

nges

and

err

ors.