Roland van der Veen- Knots, Continued Fractions and DNA

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    Knots, Continued Fractions and DNA

    Roland van der Veen

    AiO Seminar Mathematics: Friday 17-11, 16:00-17:00, Room P.014

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    A knot is a circle embedded in space

    History of knot theory

    Rational tangles and continued fractions

    Classification of rational tangles and

    rational knots

    Application to DNA

    =

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    Peter Tait (1883)

    http://www-groups.dcs.st-and.ac.uk/~history/PictDisplay/Tait.html
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    Method: alternating knot diagrams

    Flype move:

    Tait Flyping Theorem (proven in 1990):

    Two alternating diagrams give rise to the

    same knot iff they are related by a sequence

    offlypes.

    T

    T

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    John Conway (1970)

    Tangles

    Rational tangles:Start with 0 and twist an oddnumber of times:

    right, down, right, down, right,

    Start with ,and twist an even number of times:down, right, down, right,

    0 T

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    Conways Classification Theorem

    Let S and T be two rational tangles with twist

    sequences s1,, sm and t1,, tn.

    S and T are equal iff [sm

    ,, s1] = [t

    n,, t

    1]

    [a ,b,c,d,e,f] is the

    continued fraction:

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    Proof, Louis Kauffman (2003)

    Imitate the arithmetic of continued fractionswith tangles:

    S T+ = S T

    -T is T with all crossings reversed

    3 -2 3 -2+ = 1

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    A rational tangle can be written as its own

    continued fraction!

    T

    = T-1

    22

    1

    2,3

    continued fraction: [3,2] = 3 +12

    3 +21 = =

    2,3

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    Every continued fraction has a unique canonical

    form: a positive/negative continued fraction of

    odd length.

    Tangles with equal fractions are equal:

    Bring the tangles into canonical form.

    The corresponding fractions are also incanonical form.

    The canonical form is unique for fractions, so

    the fractions are equal.

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    Conversely: Tangles with different

    fractions are different.

    Bring the fractions into canonical continued fraction

    form.

    Bring the tangles into canonical form. The forms look

    the same! The corresponding diagrams are alternating, so they

    are related by flypes (Tait flyping theorem).

    Flypes do not change the fraction. The fractions are assumed to be different, so the

    tangles are not the same.

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    Rational knots

    A rational knot is the closure of a rational tangle.

    T

    Theorem:

    cl(p/q) and cl(p/q) are equal iff

    1. p = p2. q = q (mod p) or qq = 1 (mod p)

    Notation: cl(T) = cl(3) =

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    Application to DNA

    X

    1.The DNA loop is twisted n times.2.The enzyme X replaces the tangle 0 by r.

    3.The result is the knot cl(10/7).

    4.Determine r without knowing n.

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    Enzyme X

    cl(1/n + r) the result is cl(10/7)

    nr + 1 = 10 and

    either n = 7 (mod 10) or 7n = 1 (mod 10) nr = 9, so n = 1, 3, 9.

    The possibilities are n = 3

    Enzyme X acts by replacing the 0 tangle by 3

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    The infinite golden braid