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1 | Casey Roberts Casey Roberts Willing to relocate [email protected] Summary of Qualifications Ensured projects and lab meet FDA, clinical GMP, GCP, and GLP regulations Worked with primary cell extraction, culture, reprogramming, and characterization Antibody verification and use to characterize cells Authored and maintained technical protocols, including SOPs Directly worked with senior executives to determine a projects patent eligibility including IP research presentations and patent searches Team lead of a 3 member group Presented at international conferences and to undergraduate and graduate student seminars Set up and helped work with QC to move projects into development Generate processes that could be scaled up or scaled down Basic knowledge Spanish, French, and Hebrew Education March 2015 Ph.D. Biomedical Research, Eastern Virginia Medical School, Norfolk, Virginia Mentor: Roy Ogle, Ph.D. (Chair of the School of Medical Diagnostic & Translational Sciences) LifeNet Health Advisor: Silvia Chen, PhD, MBA December 2011 M.S. Biomedical Research, Eastern Virginia Medical School, Norfolk, Virginia Mentor: Dr. Roy Ogle, Ph.D. (C.S.O. of LifeNet Health) December 2008 B.S. Biology and Minor in Chemistry, Christopher Newport University, Newport News, Virginia Research and Techniques 05/2011-03/2015 PhD, Eastern Virginia Medical School with Research at LifeNet Health’s Institute of Regenerative Medicine Investigated and developed an efficient differentiation system of induced pluripotent stem cells (iPSC) to endodermal, ectodermal, and mesodermal cell lineages for scale Set up a laboratory and lab equipment Set up and maintained flow cytometry equipment (Accuri C6) Characterized primary cells through quantitative and qualitative methods including cell imaging and gene expression analysis Verification of antibodies for use with flow cytometry, immunofluorescence, and western blotting Achieved project goals through project planning and budgeting with MS Office and SAP

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Page 1: Roberts.CV.Scientist

1 | C a s e y R o b e r t s

Casey Roberts

Willing to relocate

[email protected]

Summary of Qualifications

• Ensured projects and lab meet FDA, clinical GMP, GCP, and GLP regulations

• Worked with primary cell extraction, culture, reprogramming, and characterization

• Antibody verification and use to characterize cells

• Authored and maintained technical protocols, including SOPs

• Directly worked with senior executives to determine a projects patent eligibility including IP research

presentations and patent searches

• Team lead of a 3 member group

• Presented at international conferences and to undergraduate and graduate student seminars

• Set up and helped work with QC to move projects into development

• Generate processes that could be scaled up or scaled down

• Basic knowledge Spanish, French, and Hebrew

Education

March 2015 Ph.D. Biomedical Research, Eastern Virginia Medical School, Norfolk, Virginia

Mentor: Roy Ogle, Ph.D. (Chair of the School of Medical Diagnostic &

Translational Sciences)

LifeNet Health Advisor: Silvia Chen, PhD, MBA

December 2011 M.S. Biomedical Research, Eastern Virginia Medical School, Norfolk, Virginia

Mentor: Dr. Roy Ogle, Ph.D. (C.S.O. of LifeNet Health)

December 2008 B.S. Biology and Minor in Chemistry, Christopher Newport University,

Newport News, Virginia

Research and Techniques

05/2011-03/2015 PhD, Eastern Virginia Medical School with Research at LifeNet

Health’s Institute of Regenerative Medicine

Investigated and developed an efficient differentiation system of induced pluripotent stem cells

(iPSC) to endodermal, ectodermal, and mesodermal cell lineages for scale

Set up a laboratory and lab equipment

Set up and maintained flow cytometry equipment (Accuri C6)

Characterized primary cells through quantitative and qualitative methods including cell imaging and

gene expression analysis

Verification of antibodies for use with flow cytometry, immunofluorescence, and western blotting

Achieved project goals through project planning and budgeting with MS Office and SAP

Page 2: Roberts.CV.Scientist

2 | C a s e y R o b e r t s

Authored and maintained technical protocols, including SOPs

Determined patentability of projects by directly working with senior executives with IP research

presentations and patent searches

Team lead of a 2 member group that has characterized and researched developed iPSC lines

Ensured projects meet clinical GMP (Good manufacturing practice) and GLP (Good lab practice)

regulations

Collaborated with Research Scientists on various projects

03/2010-05/2011 Master’s Student, Dr. Roy Ogle Lab

Investigated the role of adipose extracellular matrix in adipose stem cell culture and differentiation

Designed experiments and wrote mock NIH grant proposals

01/2010-03/2010 Master’s Student Lab Rotation, Dr. Larry Sanford

Performed experiments and analyses for neurological sleep studies

10/2009-12/2009 Master’s Student Lab Rotation, Dr. Elena Galkina

Performed experiments for atherosclerosis and immunology studies

Publications:

Roberts C, Chen S, Toole A, Francis M, Ogle RA, Sola N, Ogle RC, Sachs P Efficient generation of

therapeutic quantities of MSCs from osteoblast-derived iPSCs. (Under Revision at Journal of Stem

Cells Translational Medicine).

Roberts C, Chen S, Toole A, Sola N, Francis M, Ogle RA, Sachs P and Ogle RC Derivation,

differentiation, and growth of definitive endodermal cells from reprogrammed donor cells.

(Submitted to Journal of Stem Cells and Regenerative Medicine).

Breathwaite E, Dutta S, Sachs PC, Roberts C, Chen S, Ogle RC, and Francis MP. Decellularized Human

Placenta for Therapeutic Somatic and Stem Cell Cultures, and Complex Extracellular Matrix

Proteomics. Prepared for Nature Biotech. (Under Review by LifeNet Health for intellectual

property).

Rough RR, Breathwaite E, Sachs PC, Roberts C, Chen S, Ogle RC and Francis MP. Electrospun Human

Extracellular Matrix Support Induced Pluripotent Stem Cell and Neuron Cultures. Preparated for

“Biomaterials.” (Under Review by LifeNet Health for intellectual property).

Oral Presentations at Conferences and Organizations:

Roberts, C., Chen, S., Toole, A., Sola, N., Sachs, P., and Ogle, R.C. Reprogramming, and differentiation

of human donor cells. LifeNet Health Quality Control 04/2014

Roberts, C., Chen, S., Sachs, P., and Ogle, R.C. Reprogramming donor cells and differentiation to

definitive endodermal cells. CNU Seminar 03/2014

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3 | C a s e y R o b e r t s

Roberts, C., Chen, S., Toole, A., Sachs, P., and Ogle, R.C. Osteoblast-derived iPSCs generate

mesodermal and endodermal cell types. EVMS Graduate Student Symposium 03/2014

Roberts, C., Ogle, R.A., Chen, S., Sachs, P., and Ogle, R.C. Poster: Derivation, differentiation, and

growth of definitive endodermal cells from reprogrammed donor cells. ISSCR, Boston, 06/2013

Roberts, C., Sachs, P., Chen, S., Ogle, R.C. Poster: Differentiation and culture of induced pluripotent

stem cells to definitive endodermal cells EVMS Research Day, 10/2012

Roberts, C., Ogle, R.A., Ogle, R.C. The Adipose Tissue Extracellular Matrix Role on Adipose Stem Cell

Differentiation. International Federation for Adipose Therapeutics and Science at the 2011

conference, 11/2011

Roberts, C., Ogle, R.A., Ogle, R.C. Regenerative Medicine and Adipose Tissue. Biomedical Sciences

Student Organization Meeting, 02/2011

Certifications

HIPAA, CITI, LATA, RS 2000 X-Ray Irradiator training

Software Proficiencies

Android & Windows and Apple operating systems; Microsoft Project, Powerpoint, Excel, Word,

Outlook; SPSS statistical software; Adobe Photoshop, ImageJ, EndNote, Zeiss Zen image acquisition and

analysis, GraphPad Prism 6, BLAST, & PubMed; Thomson Innovation patent search engine.

Societies

BioFlorida Society

Virginia Biotechnology Association

Tissue Engineering and Regenerative Medicine International Society

International Society of Stem Cell Research

American Society for Cell Biology

Biomedical Sciences Student Organization, Eastern Virginia Medical School, Treasurer and Vice

President

Languages

English (Native Speaker)

French (Advanced)

Spanish (Beginner)