RNA nanotechnology for computer design and in vivo computation

by Meikang Qiu, Emil Khisamutdinov, Zhengyi Zhao, Cheryl Pan, Jeong-Woo Choi, Neocles B. Leontis, and Peixuan Guo

Philosophical Transactions AVolume 371(2000):20120310

October 13, 2013

©2013 by The Royal Society

Comparison of the electronic computer and a molecular-scale computer.

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

Logic-gate systems with Ag+ and Hg2+ ions as inputs and electrochemical signals as output detected by differential pulse voltammetry (DPV).

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

Historical outline of RNA nanotechnology.

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

Significance and uniqueness of RNA nanotechnology.

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

Fabrication of RNA nanoparticles.

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

Workflow diagram of functional RNA construction based on the pRNA molecule.

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

Illustration of toolkits to obtain RNA nanoparticles.

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

Application RNA nanotechnology for computer design.

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

AFM images of pRNA nanoparticles obtained by ‘hand-in-hand’ interaction following toolkit no. 1 [87].

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

AFM images of pRNA nanoparticles obtained by ‘foot-to-foot’ interaction following toolkit no. 2 [87].

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

AFM images of pRNA nanoparticles obtained by ‘foot-to-foot’ interaction following toolkit no. 3 [87].

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society

The development path of molecular-scale computing.

Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371:20120310

©2013 by The Royal Society