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5%
Birth
Hearing loss
Hypertension
Obesity
Smoking
Depression
Physical inactivity
Low social contact
Diabetes
8%
9%
5%
4%
3%
2%
1%
2%
1%
7%
Less education
Potentiallynon-modifiable
65%
Potentiallymodifiable
35%
Late life
Midlife
Early lifeHearing loss
Percentage reduction in new cases of dementiaif this risk is eliminated
HypertensionObesity
Smoking
DepressionPhysical inactivity
Social isolationDiabetes
8%
9%
5%
%
4%
3%
2%
1%
2%
1%
7%
Less education
Potentiallynon-modifiable
65%
Potentiallymodifiable
35%
The best science for better lives
The Lancet Commission presents a new life-course model showingpotentially modifiable, and non-modifiable, risk factors for dementia.
ApoE ε4 allele
Risk factors for dementia