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Reviewers, Volume 4* (1990) The Editors would like to thank the Editorial Board and the following scientists who were kind enough to review papers and provide advice during 1990. Your help has been invaluable and is greatly appreciated.
*From November 1, 15, 1990
1989 to November
Aaronson, Stuart Abelson, John Acheson, Nicholas Adhya, Sankar Aloni, Y. Alt, Fred Anderson, Phil Martinez Arias, Alfonso Arndt, Kim Artavanis-Tsakonas, Spyros Ausubel, Frederick Baker, Bruce Baltimore, David Bard, J. Bautch, Victoria Beach, David Bedinger, P. Belasco, foel Bentley, D. Berk, Arnold Bernstein, Alan Bert, Arnold Bevan, Michael Biggin, Mark Bingham, Paul Bird, Adrian Bishop, Michael Blackburn, Elizabeth Blau, Helen Bogenhagen, Daniel Borst, Piet Bothwell, Al Brandhorst, Bruce Brawerman, George Britt, Anne Broach, James Brockes, J. Brown, Donald Buchman, Andrew Burhans, William Burr, Ben Calame, Kathryn Calendar, Richard Carlson, Mary Ann Carroll, Sean Cepko, Connie Chalfie, Martin Chater, Keith Childs, Geoff Chory, Joanne Clayton, David Clements, J.B. Cleveland, Donald Coen, Enrico
Coffin, John Cole, Michael Copeland, Neil Costantini, Frank Cozzarelli, Nicholas Crabtree, Gerald Craig, Elizabeth Cross, Fred Cullen, Bryan R. Curran, Tom Davidson, D. Davidson, Eric Davis, Mark DePamphilis, Melvin L. Desplan, Claude Deutsche:, Murray Devreotes, Peter Dexter, M. Di Maio, Dan DiNardo, Stephen Dreyfuss, Gideon Duboule, Denis Dunaway, Marietta Dynan, William Earnshaw, William Echols, Harrison Ehrenfeld, Ellie Eichele, Gregor Eicher, Eva Eisenman, Robert Elgin, Sarah Emerson, Charles Engel, Douglas Evans, Ron Fan, Hung Federoff, Nina Fields, Stanley Finnegan, D. Finney, Mike Firtel, Richard Frendewey, David Freundlich, Marty Friedman, David Fristrom, James Fuchs, Elaine Futcher, Bruce Fyrberg, Eric Gallimore, Phil Ganem, Don Garber, Richard Gaynor, Richard Gehring, Walter Geiduschek, E.P. Gelbart, William Gellert, Martin Georgeopoulos, Constantine Gergen, Peter Gerisch, Gunter Gilman, Mike Glover, David Gold, Larry Gonzalez, F. Goodman, Corey Gordon, C.
Gottesman, Susan Gralla, Jay Graves, Barbara Green, Howard Green, Michael Greenberg, Michael Greenblatt, Jack Greene, Warner Greenstein, Michael Greenwald, Ira Greider, Carol Grindley, Nigel Gross, Carol Grosschedl, Rudi Groudine, Mark Gruss, Peter Gurdon, John Guthrie, Christine Hamlin, Joyce Hanafusa, Hidesaburo Hansen, Ulla Harland, Richard Hauscka, Steve Hayward, Gary Hearing, Patrick Heintz, Nat Helfman, David Hernandez, Nouria Hershey, John Herskowitz, Ira Higgins, C. Hirmebusch, Allan Hirsh, Jay Hopkins, Nancy Horowitz, Ira Howard, Ken Howley, Peter Huen, D. Hughes, Steve Hunt, Tim Hunter, Tony Ingham, Phillip Jackson, I. Jan, Yuh-Nung Johnson, Alexander Johnson, Peter Joho, Keith Jolicouer, Paul Jones, Katherine Joyner, Alex Kadesch, Tom Kadonaga, James Kaiser, Dale Kao, C. Cheng Karan, James Karin, Michael Kam, J.
Kedinger, Claude Keller, Walter Kelly Tom Kessin, Richard Kieff, Elliot Kingston, Robert Kirschner, M.
GENES & DEVELOPMENT 2409
Kleckner, Nancy Klessig, Daniel Klobutcher, Larry Knowles, Barbara Kolodner, Richard Komberg, Roger Komberg, Thomas Kouzarides, T. Krainer, Adrian Krasnow, Mark Krumlauf, Robb Kucherlapati, Radu Laithe, R.
Lamb, Christopher J. Lambowitz, Alan Lamond, A. Landy, Arthur Lane, David Lawrence, Peter Lehman, Ruth Lengyel, Peter Levin, Joshua Levine, Amold Levine, Michael Levy, Michael Ley Timothy Lilley, D. Lindahl, Lasse Linney, Elwood Lonssdale, Loomis, Bill Losick, Richard Lovell-Badge, Robin Luktenhaus, Joe Lund, Elsabet MacDonald, Paul MacDonald, Ray Mak, Tak Maniatis, Tom Martienssen, Rob Martin, Gail Marzluff, William F. Matrisian, Lynn Matton, D. McClure, William McCormick, Shelia McGhee, James McKeown, Michael McMahon, Andrew Melton, Douglas Meyer, Barbara Meyerowitz, Elliott Moore, Claire Moran, Betty Morimoto, Richard Mount, Steve Mller, Martin Muller, R. Nabel, Gary Nadal-Ginard, Bernardo Neidhardt, F. Nemer, Martin
Nevins, Joseph Newton, Austin Nienhuis, Arthur Nurse, Paul O'Hare, Peter Odenwald, Ward Olson, Eric Osley, Mary Ann Parada, Luis Pardue, Mary Lou Parker, Malcolm Paule, Marvin Peebles, Craig Pelham, Hugh Peterlin, Matija Piatt, Terry Postlethwait, J. Prives, Carol Proudfoot, Nicholas J Raff, E.G. Ransone, Lynn Ready, Donald Reed, Steve Reeder, Ronald H. Reik, W. Rice, Andrew Rigby, Peter Rio, Don Risser, Rex Roberts, Jeff Robertson, Liz Roeder, Robert Rosbash, Michael Rosenberg, Naomi Rosenfeld, M, Geoff Rossant, Janet Rubin, Gerry Ruvkun, Gary Sachs, Alan Saedler, H. Sapienza, Carmen Sassone-Corsi, Paolo Schaap, Pauline Schedl, Paul Schibler, Ueli Schpbach, Trudi Schutz, G. Segraves, William Setlow, Peter Sharp, Phillip Shenk, Thomas Sherr, Charles Sherratt, David Shimkets, L. Shulman, LaDonne Shur, Barry Silhavy, Tom Simons, Robert Sippel, E.
Skowronski, Jacek Slack, Jonathan
Smith, Alan Smith, J. Somerville, Christopher Sonenberg, Nahum Spradling, Allan Sprague, George Stamatov-Annopoulous, G. Stanley, Pamela Stark, George Steitz, Joan Stellar, Herman Stenlund, Arne Sternglanz, Rolf Stevenin, F.J. Steward, Ruth Stiles, Chuck Stillman, Bruce Strickland, Sidney Struhl, Gary Struhl, Kevin Surani, M. Azim Szostak, Jack Tatchell, Kelly Tegtmeyer, Peter Thorner, Jeremy Thummel, Carl Tilly, Kit
Timberlake, William E. Tonegawa, Susumu Townes, Timothy Travers, A.A. Treizenberg, Steve Ullrich, Axel Ullu, Elizabetta Vassalli, J.D., Verma, Inder Wahl, Geoffrey Warner, Jonathan R. Wasylyk, C. Weatherall, D. Weinberg, Robert Weiner, Alan Weintraub, Harold M. Wensink, Pieter Werb, Zina Westphal, Henry Wickens, Marvin Wickner, Sue Wieschaus, Eric Wigler, Mike Wilkinson, D. Williams, Jeff Willison, Keith Winston, Fred Wolgemuth, Deborah Wright, Christopher Yamamoto, Keith Yaniv, Moshe Young, Michael Young, Richard Ziff, Edward Zipursky, Lawrence
2410 GENES & DEVELOPMENT
Advertisers, Volume 4 Academic Press
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Wiley-Liss Books
GENES & DEVELOPMENT 2411
Author Index, Volume 4 (1990) Abelson, J., 1185 Abmayr, S.M., 2086 Abrams, L., 835 Adhya, S., 410 Admon, A., 822, 1741 Affolter, M., 1224 Agabian, N., 2121 Ahmed, Y.F, 1014 Ahn, M.-H, 1611 Albert, V.R, 43 Alessi, D., 2210 Ali, Z , 1079 Ammerer, G., 299 Antoniou, M., 1007 Apelian, D., 1396 Ares, Jr., M., 2132 Arias, A.M., 2086 Artavanis-Tsakonas, S., 464, 2169, 21^ Ashbumer, M., 905 Ayyub, H., 1588 Azpiazu, N., 2098 Baeuerle, P.A., 1975 Bailly, M., 401 Baker, B.S., 89, 789 Baker, N.E., 1848 Ball, Jr., A.R., 1677 Baltz, T., 1374 Banroques, J., 1185 Barbacid, M., 683 Barberis, A., 849 Barkan, A., 331 Barras, E., 1528 Easier, K., 728 Bate, M., 2086 Baumhueter, S., 372 Beach, D., 9 Beckmann, H., 167 Bednarz, A.L., 2366 Behringer, R.R., 380 Bell, S.P., 943 Benchimol, S., 1 Bender, W., 1573 Benzer, S., 806 Berg, P., 157 Berget, S.M., 1552 Berk, A.J., 151 Bernstein, A., 390 Bernstein, S.I., 885 Berte, C , 1528 Bettler, D., 1688 Beug, H., 1650, 1663 Bier, E., 190 Binkley, J., 1790 Blackman, R.K., 1114 Blochlinger, K., 1322 Bodmer, R., 1322 Boeke, J.D., 324 Bonner, A.S., 1701 Boocock, M.R., 2366 Bordonn, R., 1185, 2264 Bos, T.J., 1677 Boshart, M., 1437 Botchan, M.R., 123 Botstein, D., 2252
Bottomly, K., 1304 Boulukos, K.E., 401 Brady, C , 390 Brandhorst, B.P., 111 Breitenbach, M., 1775 Brennan, T.J., 582 Brice, M., 1637 Bnll, S.J., 968 Brinster, R.L., 380 Britten, R.J., 1999 Briza, P., 1775 Broide, R.S., 695 Brow, D.A., 1345 Brown, B.D., 1925 Brown, D.D., 1107, 1602, 1917 Brown, J.L., 624 Bryner, R.S., 667 Buchman, A.R., 503 Burgess, R.R,, 2048 Busslinger, M., 849 Calame, K., 1404 Calzone, F.J., 1999 Camerini-Otero, C.S., 1951 Camerini-Otero, R.D., 1951 Campbell, P.L., 1252 Capaci, T.M., 1516 Carcamo, J., 1611 Carding, S.R., 1304 Carlson, L.M., 536 Carpenter, R., 1483 Carpousis, A.J., 873 Celada, A., 1451 Chambon, P., 137 Chan, K., 63 Chang., C.H.W., 1677 Chaplin, D., 978. Chapman, A.L., 18 Chasman, D.I., 503 Chen, C.-H., 1365 Cho, K.W.Y., 1910 Chojkier, M., 1541 Chua, N.-H., 1899 Cianetti, L., 180 Clark, CD. , 2252 Cochrane, A.W., 1357 Coen, E.S., 1483 Collier, V.L., 885 Conboy, M.J., 1128 Conley, P.B., 372 Connell, L., 1862 Conway, G.C., 1158 Corces, V.G., 1505 Cortes, P., 1611 Costa, R.H., 1427 Courtois, C , 372 Crabtree, G.R., 372, 1823 Craven, M.G., 2210 Cullen, B.R., 1014 Dale, M., 2157 Darby, M.K., 1602 Darnell, J.E., Jr., 1427, 2353 Davidson, E.H., 1999 Davis, R.W., 157, 740 de Bisschop, N., 955
De Robertis, E.M., 1910 Decker, G., I l l Deininger, P.L., 2333 Dellmg, U., 1365 Descombes, P., 1541 Diederich, R.J., 2188 Dillon, P.J., 1357 Din, S.-u., 968 Dohrmann, C , 2098 Dolan, J.W., 492 Draper, B.W., 932 Driscoll, M.C., 1637 Dubnau, D., 860 Dubnau, E., 860 Duffy, J.B., 1701 Duncan, 1., 1936 Dutta, A., 243 Eaton, S., 1068 Echols, H., 410 Edwards, C.A., 372 Edwards, D.R., 2308 Edwards, K.A., 885 Eichele, G., 1267 Eichinger, D.J., 324 Eisen, R , 1374 Eisenman, R.N., 2025, 2235 Eldon, E.D., 111 Elledge, S.J., 157, 740 Ellinger, A., 1775 Ellisman, M.H., 806 Elsholtz, H.P., 43 Emerson, Jr., C.P., 567 Engle, J.D., 1650 Enver, T., 1637 Epner, E., 1637 Errede, B., 1862 Evans, M.J., 1023 Fairman, M.P., 968 Falvey, E., 1541 Fan, C.-M., 29 Fey, S., 1528 Fields, S. 492 Fiering, S., 1823 Finkelstein, R., 1516 Finn, L.A., 98 Firtel, R.A., 18, 419, 596 Fleming, R.J., 464,2188 Flenniken, A.M., 1094 Flint, J., 1611 Fodor, E., 1035 Forrester, L., 390 Forrester, W.C, 1637 Fortini, M.E., 444 Fox, C.A., 2287 Frasch, M., 2098 Fredrickson, T.N., 233 Freeling, M., 331 Freimuth, P., 1197 Fridell, R.A., 559 Friedel, C , 1688 Friedman, A.D., 1416 Friedman, D.I., 2210 Fromental, C , 137 Fu, X.-Y., 1753
Fuchs, E., 1985 Gallic, D.R., 1149 Ganem, D., 764 Gavin, B.J., 2319 Gehring, W.J., 1224 Gelbart, W.M., 1114 Gergen, J.P., 1701 Ghysdael, J., 401, 1663 Giddens, E., 390 Giglio, L.M., 2146 Giroud, C , 1374 Gizang-Ginsberg, E., 477 Glineur, C , 1663 Gober, J.W., 1494 Gold, L., 1790 Golemis, E., 233 Goodman, C.S., 2169 Goodstein, M., 1999 Gottesman, S., 2036 Grabowski, P.J., 1172 Graves, B.J., 667, 1451 Graves, M.K., 372 Green, M.R., 2376 Greenberg, M.E., 255 Greene, W.C, 1014, 1875 Gregor, P.D., 1730 Grimaila, R., 1114 Gross, C.A., 2202 Grosveld, F., 1007, 2075 Groudine, M., 75, 1637 Guarente, L., 1714 Gunderson, S.I., 2048 Gunther, C.V., 667, 1451 Guthrie, C , 1185, 1345, 2264 Ha, I., 1611 Haasch, D., 978 Haber, R., 410 Fiaberstroh, L., 596 Hafen, E., 728 Hagman, J., 978 Hake, L.E., 63 Hama, C , 1079 Hanafusa, H., 243 Hanly, S.M., 1014 Hansen, U., 287 Harland, R.M., 932, 1925 Hart, A .C, 1835 Hartley, J.W., 233 Hartshome, T., 2121 Hartz, D., 1790 Hausner, T.-P., 2146 Hayday, A.C, 1304 Hayward, W.S., 75 Heath, J.K., 2308 Heberlein, U., 712 Helfman, D.M., 98 Hennessy, K.M., 2252 Hernandez, N., 2061 Herrero-Sanchez, C , 1528 Herzenberg, L.A., 1823 Higgs, D.R., 1588 Hirai, H., 2342 Hjorth, A.L., 419 Ho, W.Y.-W., 1197
2412 GENES & DEVELOPMENT
Hoffmann, A., 1141 Hoffmann, F.M., 1114, 2011 Hoffmann, H.M., 1172 Hogness, D.S., 204 Hollingsworth, T., 1790 Holloway, J.M., 695 Holmgren, R.A., 1053 Hopkins, N., 233 Horikoshi, M., 1141, 1899 Horvitz, H.R., 357 Howard, G., 1316 Hsieh, P., 1951 Hu, Y.-F., 1741 Huang, H.-C, 287 Hughes, S.H., 1462 Humphries, E.H., 536 Hunt, T., 2157 Igel, A.H., 2132 Ingraham, H.A., 695 Inouye, S., 1396 Irick, H.A., 1114 Iwasaki, K., 2299 Jackson, S.P., 659 Jacobs, J.R., 2169 Jacques, J.-P., 1801 Jan, L.Y., 190, 1322 Jan, Y.N., 190, 1322 Jang, S.K., 1560 Jantzen, H.-M., 943 Jarman, A.P., 1588 Jasin, M., 157 Jenkinson, E.J., 1304 Johal, L., 2061 Johnson, F.B., 1044 Johnson, L.L., 2210 Johnson, T.M., 1316 Joho, K.E., 1602 Jones, R.W, 1252 Jordan, C.T., 220 Kadesch, T , 167 Kafatos, F.C., 1128 Kaiser, D., 896 Kal, A.J., 1964 Kania, M.A., 1701 Karch, F., 1573 Karim, F.D., 1451 Kasai, Y., 1611 Kassis, J.A., 433 Katagiri, F., 1899 Kedes., L., 1811 Keller, S.A., 1316 Kellerman, K.A., 1936 Kelly, A.M., 1462 Kessler, D.S., 1753 Kim, S.H., 1602 Kim, S.K., 357, 896 Kimmel, B.E., 712 King, D.L., 1128 Kingston, R., 1304 Klein, W.H., 111 Klemsz, M.J., 1451 Knuth, M.W., 2048 Ko, L.J., 1650 Kobr, M., 1528 Kolodziej, P.A., 313 Komberg, R.D., 503
Komberg, T.B., 1068, 1079 Kovelman, R., 646 Kozak, D., 1158 Krainer, A.R., 1158 Krmer, H., 1835 Krasnow, M.A., 1044 Kretzner, L., 1766 Krinke, L., 2223 Kris, R.M., 955 Krisch, H.M., 873 Kristie, T.M., 2383 KrolJ, K.L., 1053 Kronert, W.A., 885 Kronstad, J.W., 1384 Kukowska-Latallo, J.F., 1288 Kulesh, D., 835 Kulozik, A., 1252 Kunkel, B., 525 Kuo, C.J., 372 Kuo, H.-c, 1172 Kyes, S., 1304 La Brousse, F.C., 567 Labhart, P., 269 Lagrou, C, 401 Lai, E., 1427, 2353 Lam, L., 1688 Landick, R., 1623 Lane, D.P., 1 LaPointe, J.W., 503 Larsen, R.D., 1288 Lasko, P.F., 905 Laspia, M.F., 2397 Lau, Y.-F.C, 63 Leask, A., 1985 Lee, D.N., 1623 Lemischka, I.R., 220 Leonard, M.W., 1650 Leong, S.A., 1384 Lepesant, J.-A., 922 LeSrange, R.C., 75 Levy, D.E., 1753 Liao, S.-M., 313 Liao, X., 1766 Lichtsteiner, S., 1541 Lida, J., 1588 Lillie, J.W., 2376 Lindenbaum, M.H., 2075 Litvin, O., 1427 Logan, S.K., 613 Lorch, Y., 503 Losick, R., 525 Lowe, J.B., 1288 Lue, N.F., 503 Luscher, B., 1741, 2025, 2235 MacDonald, C.C, 2112 Mach, B., 1528 Madhani, H.D., 2264 Maki, R.A., 1451 Maldonado, E., 1611 Malim, M.H., 1014 Manak, J.R., 955 Mandai, N., 410 Maniatis, T., 29, 2086 Manley, J.L., 2112 Mariani, B.D., 1128 Martienssen, R., 331
Martm, D.I.K., 1886 Martm, K.J., 2376 Martin-Zanca, D., 683 Masucci, J.D., 2011 Mathews, M.B., 2397 Mattila, P.S., 1823 Mattox, W., 789 Mattson, D.M., 1936 McCormack, W.T., 536, 548 McDonagh, K.T., 993 McKearm, D.M., 2242 McKercher, S.R., 1451 McKnight, S.L., 1416 McMahon, A.P., 2319 McMahon, J.A., 2319 McStay, B., 1240 Meijer, L., 9 Meisler, M.H., 1316 Meister, A., 1035 Mendel, D.B., 372 Mercola, M., 2333 Mermod, N., 1741 Michel, F., 777 Michelson, A.M., 2086 Miltenberger, R.J., 2011 Mitsunobu, F., 1677 Mlodzik, M., 1848 Monteclaro, F.S., 1677 Montpetit, I .C, 111 Mooney, J.L., 1473 Moran, L., 752 Morham, S.G., 515 Mudd, E.A., 873 Mulligan, G.J., 98 Nagamine, C.M., 63 Nagoshi, R.N., 89 Nair, R.P., 1288 Nairn, CM. , 1357 Nasim, F.-u.H., 1172 Nelson, C., 1035 Netter, P., 777 Ney, P.A., 993 Nguyen, T., I l l Nguyen-Huu, M.C., 180 Nichols, J., 2308 Nienhuis, A.W., 993 Nishimura, T., 1677 Nitsch, D., 1437 Niwa, M., 1552 Nolan, G.P., 1823 Norris, D., 752 Northrop, J.P., 1823 Novak, U., 75 Nye, J.A., 667, 1451 O'Donnell, P.T., 885 Olesen, J.T., 1714 Olsen, H.S., 1357 Olson, E.N., 582, 1454 Olson, E.R., 2210 Orenic, T.V., 1053 Orkin, S.H., 1650, 1886 Oshima, R.G., 835 Osley, M.A., 752 Owen, J.J.T., 1304 Padgett, R.W., 1114 Paidhungat, M., 1835
Palmer, M.J., 789 Palmiter, R.D., 380 Papayannopoulou, T., 1637 Pape, L.K., 52 Parada, L.F., 683 Parsell, D.A., 277 Patel, N., 822 Pears, C., 419 Peifer, M., 1209 Penchev, R., 860 Perkins, K.K., 822 Perrimon, N., 1516 Peschle, C , 180 Pfeifer, G.P., 1277 Pick, L., 1224 Platero, J.S., 1404 Pognonec, P., 401 Pollock, J.A., 806 Pondaven, P., 9 Porter, J., 2333 Postema, C.E., 536 Pret, A.-M., 559 Pretorius, I.-M., 1588 Prezioso, V.R., 1427 Prywes, R., 955 Rathjen, P.D., 2308 Ratnasabapathy, R., 2061 Rebay, I., 464 Reed, S.I., 1332 Reeder, R.H., 269, 1240 Reinberg, D., 1611 Reith, A.D., 390 Reith, W., 1528 Renjifo, B., 233 Rhodes, N., 1862 Rice, A.P., 2397 Richardson, H.E., 1332 Riggs, A.D., 1277 Rivera, V.M., 255 Rochette-Egly, C., 137 Roeder, R.G., 646, 1141, 1730, 1899 Roman, C., 1404 Rosbash, M., 1766 Roscigno, R.F., 98 Rose, S.D., 1552 Rosen, C.A., 1357, 1365 Rosenberg, M., 1985 Rosenberg, M.P., 1316 Rosenfeld, M.G., 43, 695 Rothberg, J.M., 2169 Rottapel, R., 390 Roy, S., 1365 Rubin, G.M., 444, 712, 1848 Rudin, CM. , 978 Russell, P., 1332 Russnak, R., 764 Rutter, W.J., 1035 Ryan, T.M., 380 Saffer, J.D., 659 Sariban, E., 401 Sartorelli, v., 1811 Sauer, R.T., 277 Sawadogo, M., 1730 Scarpulla, R.C, 1023 Schaack, J., 1197 Schibler, U., 1541
GENES & DEVELOPMENT 2413
Schier, A., 1224 Schmid, A., 1688 Schmidt, M.C., 151 Schmidt-Glenewinkel, T., 1224 Schroeder, S., 1141 Schutz, G., 1437 Schweisguth, F., 922 Scott, M.P., 624 Scottgale, T .N , 464, 2188 Searles, L.L, 559 Segal, D , 1114 Segall, J, 1775 Segraves, W.A., 204 Seraphin, B , 1766 Shamah, S.M, 2333 Shapiro, L, 1494 Sharma, S.B, 344 Sharp, P.A, 2383 Sharpe, J, 1588 Shea, M J , 1128 Sheldon, M , 2061 Shen, L.-P, 1035 Sheng,M, 255 Shenk, T , 1197, 2112 Sherratt, D J , 2366 Shi, Y.-B., 1107 Shub, D.A, 777 Shuman, J, 1404 Shuman, S, 515 Signer, E.B, 344 Silacci, P , 1528 Silber, K.R, 277 Simmons, D .M, 695 Singer, V.L, 636 Sive, H.L, 932 Sladek, F.M, 2353 Slusarski, D .C , 1053 Smith, A.G, 2308 Smith, E , 1427
Smith, I , 860 Smith, M.R, 1875 Smoller, D , 1688 Smouse, D , 1516 Sollner-Webb, B, 52 Sonenberg, N , 1365 Sonoda, S, 624 Sorrentino, B.P, 993 Spana, C , 1505 Spears, P.A, 1172 Speck, N.A., 233 Spencer, C.A., 75 Spradling, A.C., 1516, 2242 St. Johnston, R.D., 1114 Standart, N., 2157 Steigerwald, S.D., 1277 Stenlund, A., 123 Stewart, A.F., 1437 Stewart, E., 2157 Stewart, J., 1623 Stiles, CD. , 2333 Stillman, B., 968 Stoeckle, M.Y., 243 Storb, U., 978 Stragier, P., 525 Straus, D., 2202 Struhl, K., 636 Stueland, C.S., 1332 Su, L.-K., 167 Su, W., 410 Sundin, O.H., 1267 Sundseth, R., 287 Susskind, M.M., 1801 Sutrave, P., 1462 Swanson, L.W., 695 Takagaki, Y., 2112 Tanguay, R.L., 1277 Taylor, W.C., 331 Temin, H.M., 2299
Thz, N., 1999 Thiebaud, P., 1999 Thomas, J., 1332 Thompson, C.B., 536, 548 Thon, G., 1374 Thummel, C.S., 1451 Thurston, S.J., 659 Tjian, R., 822, 943, 1741 Tomlinson, A., 728 Toth, S., 2308 Townes, T.M., 380 Treacy, M.N., 43 Trun, N.J,, 2036 Tuggle, C.K., 180 Turk, C, 372 Ueda, H., 624 Urban, M.B., 1975 Umess, L.D., 1451 Valdizan, M.C., 111 Van Beveren, C., 1451 vander Vliet, P.C, 1964 Van Vactor, Jr., D.L., 1835 Varmus, H.E., 2342 Vamum, S.M., 2278 Vassar, R., 1985 Veals, S.A., 1753 Verrijzer, C.P., 1964 Vincent. A., 922 Vitelh, L., 849 Vogt, P.K, 1677 Voss, J.W., 695 Walbot, V, 1149 Walter, W., 2202 Wang, C., 2333 Wang, C.K., 1141 Weber, K.S., 98 Webster, K.A., 1811 Weiffenbach, B., 1573 Weih, F., 1437
Weil, P.A., 1141 Weiner, A.M., 2146 Weinrauch, Y., 860 Weintraub, H., 932 Wensink, P.C., 613 Wickens, M., 2287 Widenhom, K., 849 Wieschaus, E., 1209 Williams, B.R.G., 1094 Williams, J.G., 419 Wilusz, J., 2112 Wimmer, E., 1560 Windle, J.J., 52 Wobbe, C.R., 636 Wood, W.G., 1588 Woodham, J.P., 1252 Wormington, W.M., 2278 Woychik, N.A., 313 Wu, C., 624 Wulff, D.L., 2223 Xu, M.-Q., 777 Xu, T., 464 Yager, L.N., 1473 Yamamoto, M., 1650 Yamazaki, K.-i., 1899 Yaoita, Y., 1917 Yedvobnick, B., 1688 Yen, D., 728 Young, R.A., 313 Zakany, J., 180 Zenke, M., 1663 Zhong, W., 2353 Ziff, E.B., 477 Zipursky, S.L., 1835
2414 GENES & DEVELOPMENT
Subject Index, Volume 4 (1990)
Abdominal A [abdA] gene, Diosophila BX-C, expression in embryos (Karch et al.), 1573-1587
Achaete-scute complex, Diosophila sea expression (Mlodzik et al.), 1848-1861
Adenovirus E lA-med ia t ed s t i m u l a t i o n of VAj
transcript ion (Kovelman and Roeder), 646-658
IVa2 promoter, TATA-like sequences required for TFIID-dependent transcription (Carcamo et al.), 1611-1622
terminal protein, mediates binding to nuclear matrix (Schaack et al.), 1197-1208
transcription, DNA binding to nuclear m a t r i x ( S c h a a c k e t a l . ) , 1197-1208
Adenovirus (Ad2), El A proteins, repression of enhansons (Rochette-Eglyetal.) , 137-150
Albumin promoter, D elements, LAP binding to (Descombes et al.), 1541-1551
Alpha-globin gene family, human, upstream positive regulatory region (Higgs et al.), 1588-1601
Alternative splicing Diosophila sex determination tia-2
RNA (Mattox et al.), 789-805 and RNA structural changes (Nasim
e t a l ) , 1172-1184 Amylase gene, r egu la to ry e l e m e n t
(Keller et al), 1316-1321 Antigen SSEA-1, embryonic, stage-spe
cific (Kukowska-Latallo et al.), 1288-1303
Antigenic variation, trypanosome VSG genes (Thon et al.), 1374-1383
Antiiihinum majus, floral homeot ic muta t ions produced by tran-sposon-mutagenesis (Carpenter andCoen), 1483-1493
Antisense RNA bacter iophage \ OOP (Krinke and
Wulff), 2223-2233 u n m a s k s c l am o o c y t e m a t e r n a l
m R N A ( S t a n d a r t e t a l . ) , 2157-2168
A n t i t e r m i n a t i o n , X N - m e d i a t e d (Friedman et al.), 2210-2222
Apolipoprotein Clll gene, and HNF-4-binding activity (Sladek et al.), 2353-2365
AP-1 binding sites Diosophila, dFRA and dJRA (Perkins
et al.), 822-834 in human p-globin dominant control
region (Ney et al.), 993-1006 AP-4 transcription factor, dimerization
domains (Hu et al), 1741-1752 ASF-1, tobacco nuclear factor (Katagiri
eta].), 1899-1909 Aspergillus nidulans, light-independent
c o n i d i a t i o n ( M o o n e y a n d Yager), 1473-1482
Autogenous regulation, S. ceievisiae his-tone locus (H2A-H2B) (Moran et al), 752-763
Autoregula t ion , Diosophila ftz enhancers (Pick et al.), 1224-1239
Avian erythroblastosis virus (AEV), v-eibA oncogene (Glineur et al.), 1663-1676
Axis formation, Xenopus laevis positional information (Cho and Ro-
bertis), 1910-1916 X. laevis, RA-sensitive period (Sive et
al), 932-942 Axon pathways, formation requires Dio
sophila slit protein (Rothenberg etal.), 2169-2187
B
B block promoter element, U6 snRNA gene e x p r e s s i o n (Brow and Guthrie), 1345-1356
Bacillus subtilis excision of sigK intervening element
(Kunkel et al.), 525-535 genetic competence regulatory gene
(Weinrauch et al.), 860-872 Bacteriophage X, OOP antisense RNA
and cIl-O mRNA (Krinke and Wulff), 2223-2233
Bacteriophage T4 Group 1 intron, 3 ' splice site selection
(Mitchel et al), 777-788 mRNA decay (Mudd et al.), 873-881
Bag-of-maibles [bam], gene, Diosophila gametogenesis (McKearin and Spradling), 2242-2251
Base -pa i r ing , b e t w e e n U2 and U6 s n R N A ( H a u s n e r e t a l . ) , 2146-2156
B-cell development, bursa of Fabricius, rearranged chicken V ^ genes (McCormack and Thompson), 5 4 8 - 5 5 8 , (Ca r l son et al .) , 536-547
B-cell-specific transcription factor, BSAP (Barberis et al.), 849-859
Beta-galactosidase, transcriptional activation, threshold event (Fiering etal.), 1823-1834
Beta-globin gene, dominant control region (Ney et
al), 993-1006 gene, dominant control region-pro
moter interactions (Antoniou and Grosveld), 1007-1013
gene family, dominant control region
(DCR) (Higgs et al.), 1588-1601 locus, LAR deletion causes chromatin
and replication alterations (Forrester et al.), 1637-1649
Bithorax Complex (BX-C), Diosophila, abdA express ion in embryos (Karch et al.), 1573-1587
Blastoderm cellularization, Diosophila, role of sry (Schweisguth et al.), 922-931
Boss gene, Diosophila retinal cell fate (Hart etal.), 1835-1847
Bovine papilloma virus (BPV-1), promoter repression by E2 trans-activator (Stenlund and Bot-chan), 123-136
BoxA sequence, importance in X N-mediated antitermination reaction (Friedman et al.), 2210-2222
Burkitt 's lymphoma, promoter-dependen t t r a n s c r i p t i o n b lock of c-myc (Spencer et al.), 75-88
Bursa of Fabricius, B-cell development rearranged chicken VLI gene (Carlson
et al.), 536-547 , (McCormack and Thompson), 548-558
c-ets-2 gene induction (chicken macrophages), in response to cMGF, LPS, and PKC activators (Bou-lukos etal.), 401-409
C-factor transmission, M. xanthus, requires cell motil i ty (Kim and Kaiser), 896-904
c-/os activation, of K18 enhancer (Oshima
et al.), 835-848 proto-oncogene
SRF enhanced DNA binding (Manak et al.), 955-967
transcriptional repression (Rivera et al.), 255-268
c-Fos, and regulation of TH gene (Gi-z a n g - G i n s b e r g a n d Z i f f ) , 477-491
c-/un ac t i va t i on , of K18 e n h a n c e r (Oshima et al.), 835-848
c-Jun protein, transformation requirements (Bos et al.), 1677-1687
c-kit point mutations, W mutant mice, and d e v e l o p m e n t a l de fec t s (Reith et al.), 390-400
c-myc p romote r -dependen t t ranscr ip t ion
block (Spencer et al.), 75-88 -related DNA-binding protein, USF
(Gregor et al.), 1730-1740 c-src, dominant negative SH2 mutants
of ( H i r a i a n d V a r m u s ) , 2342-2352
GENES & DEVELOPMENT 2415
C/EBP DNA-binding protein, homology to
I g / E B P - 1 ( R o m a n e t a l . ) , 1404-1415
homology to LAP (Descombes et al.),
1541-1551 trans-activation domains (Friedman
and McKnight), 1416-1426 Caenorhabditis elegans, lin-10 gene and
vulval cell lineage (Kim and Horvitz), 357-371
cAMP, and TAT gene transcription rate (WeithetaL), 1437-1449
cAMP response elements (CREs), within H T L V - 1 LTR ( S m i t h a n d Greene), 1875-1885
cAMP-dependent protein kinase A, Dic-tyostelium development (Firtel and Chapman), 18-28
cAMP-regulated gene, Dictyostelium SP60 (Haberstroh and Firtel), 596-612
Camphor res is tance , E. coli al tered ploidy mutants (Trun and Got-tesman), 2036-2047
Cap-independent translation, of EMCV v i r u s (Jang a n d W i m m e r ) , 1560-1572
Carboxy-terminal determinants, intracel lular prote in degradat ion (Parsell et al.), 277-286
Cardiac human actin gene, muscle-specific expression, requirements of (Sartorelli et al.), 1811-1822
Casein kinase II (CKIl), enhances SRF D N A binding (Manak et al.), 955-967
Cauliflov^^er mosaic virus (CaMV), activation sequence-1 (as-1) elem e n t ( K a t a g i r i e t a l . ) , 1899-1909
Caulobacter, fla gene transcription, IFiF requires (Gober and Shapiro), 1494-1504
CCAAT element , HAP2/3/4 binding forms transcriptional activation complex (Olesen and Guarente), 1714-1729
CCAAT-binding factor, serum and v-sic increase level of (Dutta et al.j, 243-254
CD4 locus, human, gene targeting by epitope addition (Jasin et al.), 157-166
CDC46 protein localization, S. ceievi-siae ( H e n n e s s y e t a l . ) , 2252-2263
C e l l - c e l l i n t e r a c t i o n s , Drosophila retina, boss protein (Hart et al.), 1835-1847
Cell-cel l signaling, M. xanthus C-factor transmission (Kim and Kaiser), 896-904
Cell cycle conservation of control mechanisms
in eukaryotic organisms (Richardson et al.), 1332-1344
and DNA replication (Salah-ud-Din et al), 968-977
£. coli, altered ploidy mutants (Trun and Gottesman), 2036-2047
Cell fate C. elegans lin-10 gene and vulval cell
l ineage (Kim and Horvi tz) , 357-371
determination, Dwsophila photoreceptors, ectopic expression of rough (Easier et al.), 728-739
Dwsophila retina, boss gene (Hart et al), 1835-1847
m u s c l e d e v e l o p m e n t ( O l s o n ) , 1454-1461 Commentary
progression, ribonucleotide reductase (Elledge and Davis), 740-751
Cell division cycle, S. cerevisiae CDC46 protein localization (Hennessy et al), 2252-2263
Cell moti l i ty , and M. xanthus C-sig-n a l i n g (Kim a n d K a i s e r ) , 896-904
Cell-specific expression, pancreatic enhancer function (Nelson et al.), 1035-1043
Cell-specific transcription HNF-3A (Lai et al.), 1427-1436 yeast STEll protein kinase (Rhodes et
al), 1862-1874 Cellularization, of Dwsophila blasto
derm embryo (Schweisguth et al.), 922-931
Central nervous system Dwsophila, and otd locus (Finkelstein
e t a l ) , 1516-1527 rostrocaudal domains (Tuggle et al.),
180-189 Chaopt ic gene, Drosophila photore
ceptor neurons (Pollack et al.), 806-821
Chick, homeo box genes and hindbrain segmentation (Sundin and Ei-chele), 1267-1276
Chicken embryo fibroblasts (CEFs), t ransformat ion by c-Jun and v-Jun (Bos et al.), 1677-1687
Chicken myelomonocytic growth factor.
See cMGF. Chorion gene regulation, Dwsophila,
promoter-binding factors (Shea e t a l ) , 1128-1140
Chromatin structure human (3-globin gene affected by LAR
d e l e t i o n (For res te r et al .) , 1637-1649
of U A S Q , influenced by GRF2 yeast p r o t e i n ( C h a s m a n et a l . ) , 503-514
cII-O mRNA, RNase-dependent hydrolysis mediated by X OOP anti-sense RNA (Krinke and Wulff), 2223-2233
Ciliogenesis, and expression of S. pui-puratus Spec3 gene (Eldon et ah), 111-122
cis-regulatory sites, sea urchin Cyllla, Sped, Cyl, and SM50 genes (Thiebaud et al.), 1999-2010
CKSl homologs (human), of S. ceievi-siae CKSl and S. pombe sukl"^ (Richardson et al.), 1332-1344
Class II X box, regulatory factor RFX (ReithetaL), 1528-1540
Clonal dynamics, of mouse hemato-poeitic system (Jordan and Le-mischka), 221-232
cMGF (chicken myelomonocytic growth factor), and Ets2 expression in macrophages (Boulukos et al.), 401-409
Common core proteins. See Sm proteins C o m p a r t m e n t a l i z a t i o n , B. subtilis
sigma-factors and sporulation (Kunkel et al.), 525-535
Compound eye {Dwsophila melano-gaster), cis-acting requirements of Rh3 and Rh4 genes (Fortini and Rubin), 444-463
Conidiation, l ight-dependent, Aspergillus nidulans (Mooney and Yager), 1473-1482
CpG island, of X-linked PGK-1 promoter (Pfeifer et al), 1277-1287
CRE (cAMP-responsive e lement) , of TAT gene, pro te in-DNA inter-a c t i o n s ( W e i t h e t a l . ) , 1437-1449
CREB/ATF, Tax protein trans-activation (Smith and Greene), 1875-1885
Cross-linking, U2/U6 snRNAs (Hausner et al), 2146-2156
Cstf (cleavage-stimulation factor) multi-subunit factor, polyadenylation of mammalian pre-mRNA (Ta-kagakietaL), 2112-2120
Cubitus interruptus Dominant (ci-D], Drosophila
locus, compartment-specific express ion (Eaton and Kornberg), 1069-1077
segment polarity gene (Orenic et al.), 1053-1067
Cut locus, Drosophila, sensory organ development (Biocklinger et al.), 1322-1331
Cyclin (phosphorylated), subunit of act i ve M-phase - spec i f i c H I K (Pondaven et al.), 9 -17
Cyclin A mRNA, masked message in clam oocytes (Standart et al.), 2157-2168
Cyst formation, Drosophila and bag-of-marbles gene (McKearin and Spradling), 2242-2251
Cytochrome c promoter, NRF-1 recognition site (Evans and ScarpuUa) 1023-1034
Cy toch rome P-450 superfamily, homology to yeas t D1T2 gene p r o d u c t ( B r i z a e t a l . ) , 1775-1789
2416 GENES & DEVELOPMENT
DBA-binding protein, yeast GRF2 binds to UASc ( C h a s m a n et al .) , 503-514
Deadenylation of maternal mRNAs oocyte maturation (Fox and Wickens),
2287-2298 oocyte maturation (Vamum and Wor-
mington), 2278-2286 Decapentaplegic [dpp] gene, Drosophila
i m a g i n a l d i s k s (Masucc i et al .) , 2011-2023
molecular organization of (St. Johnston et al.), 1114-1127
Diabetes, mice, amylase gene expression (Keller et al.), 1316-1321
Dictyostelium development, cAMP-dependent pro
t e i n k i n a s e A ( F i r t e l a n d Chapman), 18-28
regulation of cAMP-inducible genes (Hjorth et al.), 419-432
role of trans-acting factor GNF in regu l a t i o n of (H jo r th et a l . ) , 419-432
spore coat SP60, cis-acting regulatory reg ions of (Habers t roh and Firtel), 596-612
Differentiation inhibiting activity (DLA), controls stem cell populations (Rathjen et al.), 2308-2318
Dikaryon, plant pathogen, U. maydis ( K r o n s t a d a n d L e o n g ) , 1384-1395
Dimerization specificity, transcription f a c t o r A P - 4 ( H u e t a l . ) , 1741-1752
Dimethyl sulfoxide (DMSO), induction of globin genes in t ransients (Campbell et al.), 1252-1266
DlTl and DIT2 genes, yeast spore wall m a t u r a t i o n (Briza e t a l . ) , 1775-1789
Di tyros ine , S, cerevisiae spore wall (Briza et al.), 1775-1789
DNA, triple helix, formed by recom-binase proteins (Hsieh et al.), 1951-1963
DNA bending, and prote in-DNA interac t ions (Spana and Corces), 1505-1515
DNA binding, of SRF, enhanced by CKIl (Manak et al.), 955-967
DNA helix, stereo-specific requirements for transcription (Pape et al.), 52-61
DNA looping, and gal operon (£. coli) re-p r e s s i o n ( M a n d a l e t a l . ) , 410-418
DNA methylation, CpG islands (Pfeifer etal.), 1277-1287
DNA modification, of Mu transposable element in maize (Martienssen etal.), 331-343
DNA rearrangement, B. subtilis sigK re
a r rangement (Kunkel et al.), 525-535
DNA replication, and cell-cycle-regulated protein phosophorylation (Salah-ud-Din et al.), 968-977
DNA replication, human p-globin gene, affected by LAR deletion (Forrester et al), 1637-1649
DNA replication, S. cerevisiae CDC46 protein localization (Hennessy et al.), 2252-2263
DNA synthesis, and ribonucleotide reductase activity (Elledge and Davis), 740-751
DNA topoisomerase I, mutant alleles of ( M o r h a m a n d S h u m a n ) , 515-524
DNA tumor viruses, p53, oncogene and anti-oncogene (Lane and Ben-chimol), 1-8 Review
DNase hypersensitivity, in murine immunog lobu l in gamma locus (Hagman et al), 978-992
DNase I hypersensitive (HS) sites, and human globin gene switching (Behringer et al), 380-389
DNA-binding activity, cAMP regulation (Weith et al), 1437-1449
DNA-binding factors, sequence-specific myogenin (Brennan and Olson), 582-595
DNA-binding proteins C/EBP t r a n s - a c t i v a t i o n d o m a i n s
(F r i edman and McKnigh t ) , 1416-1426
c-myc-related family, USF (Gregor et al.), 1730-1740
Drosophila s l5 chorion gene (Shea et al), 1128-1140
erythroid GF-1 (NF-El/Eryf 1), transcriptional activator (Martin andOrkin), 1886-1898
E T S - d o m a i n ( K a r i m e t a l . ) , 1451-1453 Letter
/ tz -Fl , t ranscript ional activator of Drosophila ftz (Ueda et al.), 624-635
Ig/EBP-1 is homologous to C/EBP (Roman et al), 1404-1415
LAP and C/EBP sequence homology (Descombes et al.), 1541-1551
|xE3-binding protein TFE3 (Beckmarm e t a l ) , 167-179
Myb oncoprotein (LUscher and Ei-senman), 2235-2241 Review
novel domain of regulatory factor RFX (ReithetaL), 1528-1540
novel structure of HNF-3A (Lai et al.), 1427-1436
oct-1 POU-specific domain and POU homeo domain (Verrijzer et al.), 1964-1974
Pan-1 and Pan-2 (Nelson et al.), 1035-1043
plant transcription activator in human
s y s t e m ( K a t a g i r i e t a l . ) , 1899-1909
PRDII-BFl, zinc finger motifs of recognize same DNA sequence (Fan and Maniatis), 29 -42
sequence-specific, ets-related genes (Guntheretal . ) , 667-679
DNA-damaging agents, regulatory sub-units of ribonucleotide reductase induced by (Elledge and Davis), 740-751
DNA-nucleoprotein complex, and NGF regulation of TH gene (Gizang-Ginsberg and Ziff), 477-491
D o m i n a n t contro l region (DCR), p-globin
c l u s t e r , h u m a n (Higgs e t a l . ) , 1588-1601
globin, AP-1 sites fimction as inducib le e n h a n c e r (Ney et al .) , 993-1006
promoter interactions (Antoniou and Grosveld), 1007-1013
Dominant-negative mutants
of P D G F g e n e ( M e r c o l a et a l . ) , 2333-2341
SH2 m u t a n t s of c-src (Hirai and Varmus), 2342-2352
Dorsoventral axis, Drosophila, establishment of and Rho gene (Bier et al.), 190-203
Doublesex [dsx] gene [Drosophila], cis-acting mutations alter sex-specific RNA splicing pa t t e rns (Nagoshi and Baker), 89-110
Drosophila A P I protein, dFRA and dJRA (Perkins
et al.), 822-834 Bithorax Complex, abdA expression
in e m b r y o s (Karch et al .) , 1573-1587
CNS development, homeo domain protein encoded by otd (Finkel-s t e i n e t a l ) , 1516-1527
development, and E75 ecdysone-in-ducible gene (Segraves and Hog-ness), 204-219
dpp expression in imaginal disks (Ma
succi et aL), 2011-2023 gene structure (St. Johnston et al.),
1114-1127 dsx gene, sex-specific alternative RNA
splicing of (Nagoshi and Baker), 89-110
engrailed [en] gene, regulatory sequences that con
trol stripes (Kassis), 433-443 r eg ion - spec i f i c r e c o m b i n a t i o n
(HamaetaL), 1079-1093 represses ci-D in posterior compart
m e n t s (Eaton and Kornber), 1069-1077
exd affects homeo domain protein
GENES &. DEVELOPMENT 2417
f u n c t i o n (Peifer and Wies -chaus), 1209-1223
eye development and homeo domain rough expres
sion (Kimmel et al.), 712-727 reprogramming cell fate (Easier et
al.), 728-739 ftz gene
stability mutants (Kellerman et al.), 1936-1950
upstream element, autoregulation of independent enhancers (Pick etal.), 1225-1239
gametogenesis and bag-of-marbles gene (McKearin and Spradling), 2242-2251
h o m e o box gene S59 e x p r e s s i o n (Dohrmann et al), 2098-2111
maternal-effect gene, vasa (Lasko and Ashbumer), 905-921
MHC genes, alternative hinge regions (Collier et al.), 885-895
midline glia development and axon pathway formation require slit p r o t e i n (Rothenberg et al.), 2169-2187
nautilus [nau] gene, muscle pattern formation (Michelson et al.), 2086-2097
neurogenesis, sea gene (Mlodzik et al.), 1848-1861
neurogenic locus mastermind [mam] (SmoUer et al.), 1688-1700
Notch locus and earyl neurogenesis (Xu et al.), 464-475
ovarian enhancers of yolk prote in genes (Logan and Wensink) , 613-623
photoreceptor neurons, chaoptic gene (Pollack et al.), 806-821
Rho gene, dorsoventral axis establishm e n t and PNS deve lopment (Bier e t a l ) , 190-203
rhodopsin promoters, bipartite structu re of (Fortini and Rubin), 444-463
s l 5 chorion gene, promoter-binding factors (Shea et al.), 1128-1140
segment polarity gene, ci° (Orenic et al.), 1053-1068
segmentation gene, runt sequence and d i s t r i b u t i o n (Kania et al .) , 1701-1713
sensory organ development and cut l o c u s ( B l o c k l i n g e r e t a l . ) , 1322-1331
sry gene, blastoderm cellularization (Schweisguth et al.), 922-931
su(Hw) protein-gypsy DNA interact i o n ( S p a n a a n d C o r c e s ) , 1505-1515
retinal cell fate and boss gene (Hart et al), 1835-1847
tia-2 sex determination gene, alternative splicing (Mattox et al.), 789-805
UBX protein and transcriptional stimulation in vitro (Johnson and Krasnow), 1044-1052
vermilion {v) gene, 412 re t ro t ran-sposon insertion (Fridell et al.), 559-566
ElA adenovirus protein, synergy with HIV-1 T a t (Laspia et a l . ) , 2397-2408
ElA proteins, adenovirus-2 (Ad2), repress ion of e n h a n s o n s (Ro-chette-Egly et al.), 137-150
EAEIA adenovirus protein, transcriptional stimulation of VAj gene ( K o v e l m a n a n d R o e d e r ) , 646-658
E2 trans-activator (BPV-1), as transcriptional repressor (Stenlund and Botchan), 123-136
E75 ecdysone-inducible gene, Droso-phila (Segraves and Hogness), 204-219
Early response genes, avian c-ets-2 (Bou-lukos e t a l ) , 401-409
Ecdysone response, Diosophila, genetic regulatory hierarchy (Segraves and Hogness), 204-219
Ectodermal differentiation, and Droso-phila Senate gene (Fleming et al), 2188-2201
Ectopic expression, of Diosphila rough h o m e o d o m a i n p r o t e i n ( K i m m e l et al .) , 1X1-111, (Basler et al), 728-739
EGF domain, Drosophila extracellular slit protein (Rothenberg et al), 2169-2187
EGF locus, Drosophila Serrate gene (Fleming et al), 2188-2201
Electron transport chain, mammalian ( E v a n s a n d S c a r p u U a ) , 1023-1034
Embryogenesis, X. laevis, positional information (Cho and Robertis), 1910-1916
Embryoid bodies, globin gene expression (Lindenbaum and Grosveld), 2075-2085
Embryon ic e c t o d e r m cel ls , 5. pur-puratus, Spec3 protein localizes to cilia and Golgi complexes (Eldoneta l ) , 111-122
Embryonic stem (ES) cells, globin gene expression (Lindenbaum and Grosveld), 2075-2085
Encephalomyocardit is virus (EMCV), cap-independent translation of (Jang and Wimmer), 1560-1572
End (3') formation, U l snRNA gene (Gunderson et al), 2048-2060
Endoribonuclease activity, and X. laevis RNA s t a b i l i t y (Brown and Richard), 1925-1935
Engrailed {en] gene [Drosophila] and exd mutations (Peifer and Wies-
chaus), 1209-1223 regulatory sequences tha t control
stripes (Kassis), 433-443 represses c i - D in posterior compart
ments (Eaton and Romberg), 1069-1077
Engrailed promoter, Drosophila, and region-specific r ecombina t ion ( H a m a e t a l ) , 1079-1093
Enhancers AP-1 sites in dominant control region
(Ney et al), 993-1006 autoregulation of Drosophila ftz pro
tein (Pick et al), 1224-1239 core element, Moloney murine leu
kemia virus, disease specificity of (Speck et al), 233-242
i m m u n o g l o b u l i n g a m m a l o c u s (Hagman et al), 978-992
ovarian, of Drosophila yolk protein genes (Logan and Wensink) , 613-623
region-specific, in mammalian CNS (Tuggle et al), 180-189
within human K18 gene, activation of (Oshima et al), 835-848
Enhancer-binding factor El2, interaction with myogenin (Brennan and Olson), 582-595
Enhansons, Ad2 ElA repression of (Ro-chette-Egly et al), 137-150
env mRNA structural region (RRE), interaction with HFV-l Rev protein (Olsen et al), 1357-1364
Epitope addi t ion, gene target ing at human CD4 locus (Jasin et al), 157-166
Erythrocytes, expression of transcription factor NF-El (Yamamoto et al), 1650-1662
Erythroid cells, AP-1 sites in dominant con t ro l region (Ney et a l ) , 993-1006
Erythroid differentiation, gag/v-erhA p r o t e i n p h o s p h o r y l a t i o n (Glineur et al), 1663-1676
Erythroid t ranscr ip t ion factor, GF-1 (NF-El/Eryf 1), activation and DNA binding by (Martin and Orkin), 1886-1898
Escherichia coh carboxy-terminal determinants of in
tracellular degradation (Parsell et al), 277-286
cell cycle, al tered ploidy m u t a n t s ( T r u n a n d G o t t e s m a n ) , 2036-2047
heat shock gene expression (Strauss et
al), 2202-2209 RNA polymerase 3-subunit, termination-altering muta-
t i o n s ( L a n d i c k e t a l . ) , 1623-1636
pseudo- templa ted t ranscr ip t ion
2418 GENES & DEVELOPMENT
(Jacques and Sussk ind ) , 1801-1810
RNase E, role in T4 mRNA decay (Mudd et al.), 873-881
ets proto-oncogene family, MSV LTR promoter binding (Gunther et al.), 667-679
Ets2 expression, in chicken macrophages (Boulukos et al.), 401-409
ETS-domain, eukaryotic DNA-binding p r o t e i n s (Karim et a l . ) , 1451-1453 Letter
Even-skipped [eve], and Drosophila segmentation defects (Kellerman etal.), 1936-1950
Evolution, studies of testis-determining Y genes (Zfy-1 and Zfy-2] in genus Mus (Nagamine et al.), 63-74
Exradenticle [Exd] gene, Drosophila, mutation affects homeo domain protein function (Peifer and Wieschaus), 1209-1223
Extracellular matrix (ECM) deposition, mice, role of TIMP (Fleimiken and Williams), 1094-1106
Extracellular protein, Drosophila slit (Rothenberg et al.), 2169-2187
Eye development, Drosophila sea gene (Mlodzik et el), 1848-1861
F9 embryonal carcinoma cells, K18 in-tron activation (Oshima et al.), 835-848
FACS/Gal assay, NF-AT transcriptional a c t i v i t y (Fiering et al .) , 1823-1834
Fetal liver, TCR 78 gene expression (Carding et al.), 1304-1315
Finger DNA-binding proteins, erythroid factor GF-1 (NF-El/Eryf 1) (Martin and Orkin), 1886-1898
fix genes {R. meliloti), in planta, regulation of (Sharma and Signer), 344-356
Flagellar genes [fla], Caulobacter, transcription requires IHF (Gober and Shapiro), 1494-1504
Flourescence-activated cell sorter, analysis of NF-AT transcriptional activity among T cells (Fiering etal.), 1823-1834
Flower development. Antirrhinum mains homeotic mutations ( C a r p e n t e r and C o e n ) , 1483-1493
Fos-related protein, Drosophila AP-1 dFRA (Perkins et al.), 822-834
Fruiting body formation, M. xanthus ( A p e l i a n and I n o u y e ) , 1396-1403
Fucosyltransferase, Lewis blood group, determines SSEA-1 expression
(Kukowska-Latallo et al.), 1288-1303
Fushi tarazu [ftz], Drosophila autoregulation of independent en
hancers (Pick et al.), 1224-1239 stability mutants (Kellerman et al.),
1936-1950 transcriptional activator of (Ueda et
al.), 624-635 F-actin, and Drosophila sry protein
(Schweisguth et al), 922-931
GAL upstream activating sequence. See UASG
Galactose {gal] operon, E. coli, DNA looping and repression of (Mandal et al.), 410-418
Gametogenesis, Drosophila, initiated by bag-of-marbles gene (McKearin and Spradling), 2242-2251
Gamma delta RNA (78 RNA), activation of (Carding et al), 1304-1315
Gamma gene regulation, independent activation (Hagman et al.), 978-992
GBF, trans-acting GBRE binding factor (Hjorthetal.), 419-432
Gene batteries, sea urchin embryos (Thiebaud et al.), 1999-2010
Gene conversion chicken, VLl, donor preference and
polarity (McCormack and Thompson), 548-558
intrachromosomal, and rearranged chicken IgL V gene segment (Carlson et al.), 536-547
Gene targeting, at human CD4 locus (Jasin et al.), 157-166
Gene switching, globin, in vitro model (Lindenbaum and Grosveld), 2075-2085
Genetic competence, B. subtilis, regulatory gene (Weinrauch et al.), 860-872
Genetic interactions, Drosophila Notch locus (Xu et al.), 464-475
Genetic screening, of DNA topoiso-merase I m u t a n t a l le les ( M o r h a m and S h u m a n ) 515-524
Genomic sequencing, X-linked CpG island (Pfeifer et al.), 1277-1287
Ghox-lab homeo domain protein, chick, h i n d b r a i n s e g m e n t a t i o n ( S u n d i n and E i c h e l e ) , 1267-1276
Glial cells, Drosophila, and slit protein (Rothenberg et al), 2169-2187
Globin gene expression, transcriptional regulation
mechanisms, GF-1 (NF-El/ Eryf 1) erythroid factor (Martin and Orkin), 1886-1898
human induction by HMBA and DMSO
(Campbell et al), 1252-1266 gene switching, in transgenic mice
(Behringer et al.), 380-389 switching, in vitro model (Linden
b a u m a n d G r o s v e l d ) , 2075-2085
Golgi complexes, S. purpuratus embryonic ectoderm cells, and Spec3 protein (Eldon et al.j, 111-122
GRF2 yeast protein, binds to UASQ creating nucleosome-free region (Chasman et al.), 503-514
GRM factor, yeast, same as PRTF factor (Ammerer), 299-312
Group I introns, 3' splice site selection (Mitchel et al.), 777-788
Growth factors. See also Nerve growth factor
DIA/LIF controls stem cell popula-t i o n s ( R a t h j e n et a l . ) , 2308-2318
dominant-negative mutants of PDGF (Mercola et al), 2333-2341
mesoderm induced, X. laevis homeo box gene activation (Cho and Robertis), 1910-1916
H
Half-helical turn spacing changes, convert frog into mouse rDNA promoter (Pape et al.), 52-61
Heat shock proteins, £. coh DnaK, DnaJ, and GrpE, sigma^^ regulation (Straus et al.), 2202-2209
HeLa cells LSF (late SV40 factor) transcription
factor (Huang et al.), 287-298 purification of SF2 splicing factor
(Krainer et al.), 1158-1171 Helix-loop-helix
domain Drosophila nau gene (Michelson et
al.), 2086-2097 of myogenic regulatory factors
(Olson), 1454-1461 Commentary
USF regulatory DNA-binding protein (Gregor et al.), 1730-1740
motif, of TFE3 (Beckmann et al.), 167-179
protein, transcription factor AP-4 (Hu etal.), 1741-1752
Hematopoiesis (mice), clonal and systemic analysis (Jordan and Le-mischka), 220-232
Hematopoietic development, ES cell system (Lindenbaum and Grosveld), 2075-2085
Hepatitis B viruses, reverse transcription (Russnak and Ganem), 764-776
Hepatocyte-specific factor, HNF-3A, regulated transcriptionally (Lai et al.), 1427-1436
GENES & DEVELOPMENT 2419
Herpes simplex virus (HSV), interaction of TIF with Oct-1 POU subdo-mains (Kristie and Sharp), 2383-2396
Herpes virus family, pseudorabies IE p r o t e i n (Mar t in et a l . ) , 2376-2382
Heteromeric protein-protein interact ion , HAP2/3 /4 CCAAT-binding complex (Olesen and Guarente), 1714-1729
Hexamethylene bisacetamide (HMBA), induction of globin genes in transients (Campbell et al.), 1252-1266
Hindbrain development, chick, meta-meric pattern (Sundin and Ei-chele), 1267-1276
Histone genes, S. cerevisiae balanced syn thes i s (Moran et al.), 752-763
Histone HI kinase (HIK), M-phase-spe-cific, activation of (Pondaven et al.), 9-17
HIV-1 gene expression, combined effects of
trans-activators on (Laspia et al.), 2397-2408
LTR, inducer of short transcripts (1ST) (Ra tnasabapa thy et al.), 2061-2074
Rev, RNA response element (Ahmed etal.), 1014-1022
Rev protein, interaction w ith structured region within env mRNA (RRE) (Olsen et al), 1357-1364
TAR RNA, Tat binding (Roy et al.), 1365-1373
HNF-1 transcription factor, broadly acting homeo domain protein (Baumhueter et al.), 372-379
HNF-3A transcription factor, cell-specific regulation of (Lai et al.), 1427-1436
HNF-4 transcription factor, novel steroid receptor family member (Sladek et al.), 2353-2365
Homeo box Drosophila BX-C (Karch et al.),
1573-1587 of Oct-1 (Kris t ie and Sharp),
2383-2396 X. laevis Xlhbox2 mRNA stability
( B r o w n a n d R i c h a r d ) , 1925-1935
Homeo box genes chick hindbrain segmentation (Sundin
andEichele), 1267-1276 Drosophila S59 (Dohrmann et al.),
2098-2111 Drosophila rough, photoreceptor spec
ification (Basler et al.), 728-739 mammalian Hox-1.3 and Hox-5.1, and
region-specific enhancers (Tuggle et al.), 180-189
X. laevis, activation by mesoderm-in-
ducing growth factors and RA (Cho and Robertis), 1910-1916
Homeo domain, of oct-1 POU domain (Verrijzer et al), 1964-1974
Homeo domain proteins Drosophila
exd affects function of (Peifer and Wieschaus), 1209-1223
otd locus, necessary for CNS development (Finkelstein et al.), 1516-1527
rough, expression and misexpres-sion of (Kimmel et al .) , 712-727
HNF-1 transcription factor is broadly expressed (Baumhueter et al.), 372-379
Homeosis, Drosophila segmentation genes (Kellerman et al.), 1936-1950
Homeotic mutations, floral, in Antirrhinum majus (Carpenter and Coen), 1483-1493
Homologous recombination, intermediate three-stranded DNA (Hsieh et al.), 1951-1963
Hormonal regulation, Drosophila E75 ecdysone-inducible gene (Se-graves and Hogness), 204-219
HS sites (DNase I hypersensitive), and human globin gene switching (Behringer et al.), 380-389
HTLV-1 Rex, RNA response element (Ahmed
etal.), 1014-1022 tax gene mutants (Smith and Greene),
1875-1885 Hypersensitive sites, enhancer within
HSII (Ney et al.), 993-1006 H-2K'' gene promoter, PRDIl-BFl protein
binding to (Fan and Maniatis), 29-42
I
IE protein (pseudorabies virus), transcriptional activator (Martin et al), 2376-2382
IF3, E. coli translation initiation (Hartz etal.), 1790-1800
Imaginal disk development, Drosophila, and dpp gene (St. Johnston et al.), 1114-1127
Imaginal disks, Drosophila dpp expression (Masucci et al.), 2011-2023
Immediate early genes, c-/os transcriptional repression (Rivera et al.), 255-268
Immune response, MHC class II regulatory factor RFX (Reith et al.), 1528-1540
Immunoglobulin gamma locus, enhancers (Hagman et
al.), 978-992 genes, chicken V^ sequence diversity
as result of intrachromosomal
gene conversion (Carlson et al.), 536-547
genes, chicken, VLI pseudogene donor preference and polarity (McCor-mack and Thompson), 548-558
heavy-chain enhancer (IgH), \i.E3 motif (Beckmarm et al.), 167-179
transcription, Ig/EBP-1 is homologous to DNA-binding protein C/EBP (Roman et al.), 1404-1415
In vitro integration, of yeast Tyl retro-transposon (Eichinger and Boeke), 324-330
Induction, globin genes, by HMBA and DMSO (Campbell et al.), 1252-1266
Initiation E. coli, translation (Hartz et al.),
1790-1800 transcription, E. coli, RNA poly
merase (Jacques and Susskind), 1801-1810
Insulin-dependent element (IDE), pancreatic amylase gene (Keller et al.), 1316-1321
Integration host factor (IHF), transcriptional activation of fla genes ( G o b e r a n d S h a p i r o ) , 1494-1504
Interferon, regulation of ISGF3 nuclear translocation (Kessler et al.), 1753-1765
Interferon-stimulated gene factor-3 (ISGF3), nuclear translocation and DNA binding affinity of (Kessler et al.), 1753-1765
Interferon-p gene promoter (human), PRDII-BFl zinc finger motifs bind to regulatory domain of (Fan and Maniatis), 29-42
Interleukin-2, transcriptional activation (Fiering et al), 1823-1834
In vivo DMS footprinting, active and inactive X chromosome (Pfeifer et al.), 1277-1287
1ST (inducer of short transcripts), HIV-1 LTR (Ratnasabapathy et al.), 2061-2074
K
Kappa gene regulation, independent act iva t ion (Hagman et al.), 978-992
Keratin 18 gene, human, c-/os and c-jun activation of enhancer (Oshima et al.), 835-848
Keratinocytes, human epidermal keratin gene expression (Leask et al.), 1985-1998
Lac repressors (£. coli], and DNA looping in gal operon (Mandal et al.), 410-418
2420 GENES & DEVELOPMENT
Lambda repressor, proteolysis in £. coli (Parsell et al.), 277-286
LAP (liver transcriptional activator protein), sequence homology to C/EBP (Descombes et al.), 1541-1551
Leucine repeat elements, transcription factor AP-4 dimerization motif (Huetal.), 1741-1752
Leucine-rich repeats, Diosophila extracellular slit protein (Rothenberg et al.), 2169-2187
Leukemia inhibitory factor (LIF), controls stem cell populations (Rathjen et al.), 2308-2318
Lewis blood group, human, fucosyl-transfersase (Kukowska-La-talloetal.), 1288-1303
LF-Al DNA-binding activity, similarity to HNF-4 (Sladek et al.), 2353-2365
lin-10 gene (C. elegans], and vulval cell fates (Kim and Horvitz) , 357-371
Liver, transcriptional activator protein (LAP) (Descombes et al.), 1541-1551
Liver-specific gene expression, HNF-4 (Sladek et al.), 2353-2365
Locus activating region (LAR), deletion of human ^-globin locus (Forrester et aL), 1637-1649
Locus activation, HS sites and globin loci (Behringer et al), 380-389
Long terminal repeat (LTR), of RSV, transcription from (Dutta et al.), 243-254
Looping (DNA), and gal operon (£. coli] repression (Mandal et al,), 410-418
LSF HeLa transcription factor, two variant SV40 binding sites (Huang et al.), 287-298
Lymphoid-specific genes, and POU homeo domain protein Oct-2 (Elsholzetal.), 43-51
M
M6 and M9 alleles, SH2 mutants of c-src (Hirai and Varmus), 2342-2352
Macrophages (chicken), Ets2 expression in (Boulukos et al), 401-409
Maize, suppressible mutation (hcfl06) controlled by Mu transposable element (Martienssen et al.), 331-343
Major histocompatibility complex (MHC), class II regulatory factor RFX (Reith et al.), 1528-1540
Masking and unmasking, clam oocyte maternal mRNA (Standart et al), 2157-2168
Mastermind [mam] neurogenic locus, Diosophila (Smoller et al.), 1688-1700
Maternal mRNAs clam oocytes, unmasked by antisense
RNA ( S t a n d a r t et a l . ) , 2157-2168
deadenylation during Xenopus oocyte maturation (Vamum and Wor-mington), 2278-2286, (Fox and Wickens), 2287-2298
Maternal-effect gene, vasa protein posterior localization (Lasko and Ashbumer), 905-921
Mating response pathway, yeast, STEII protein kinase (Rhodes et al.), 1862-1874
Mating-specific promoter elements, yeast, and PRTF/GRM (Am-merer), 299-312
Mating-type locus, b, U. maydis (Kron-stad and Leong), 1384-1395
MCMl gene, yeast, encodes DNA-binding component of PRTF and GRM (Ammerer), 299-312
Mesoderm development, Diosophila nan gene, pattern formation (Michelson et al.), 2086-2097
Mesoderm induction, of X. laevis homeo box genes (Cho and Robertis), 1910-1916
Mesodermal cells, Diosophila homeo box gene S59 expression (Dohr-mannetal.), 2098-2111
Metamorphosis, X. laevis pancreatic gene regulation (Shi and
Brown), 1107-1113 and thyroid hormone receptor families
(Yaoita and Brown), 1917-1924 Mice, clonal dynamics of hematopoietic
system (Jordan and Lemischka), 220-232
Midgut cells, Diosophila homeo box gene S59 expression (Dohrmann etal), 2098-2111
Mitochondrial genetic system, NRF-1-binding sites (Evans and Scar-puUa), 1023-1034
Moloney murine leukemia virus, disease specificity of enhancer core element (Speck et al.), 233-242
Moloney murine sarcoma virus (MSV), long terminal repeat (LTR) promoter, proto-oncogene ets-1 binding (Gunther et al.), 667-679
Monoclonal antibody MAb24B10, specificity for Diosophila photoreceptors and neurons (Pollack et al.), 806-821
Morphogenesis, M. xanthus fruiting body, C-signaling (Kim and Kaiser), 896-904
Mouse development
stage-specific embryonic antigen SSEA-1 (Kukowska-Latallo et al.), 1288-1303
TIMP gene expression (Flenniken and Williams), 1094-1106
Wnt-l/int-1-related gene family (Gavin et al.), 2319-2332
dominant-negative mutant of PDGF g e n e ( M e r c o l a et a l . ) , 2333-2341
erythroleukemia cells (MELCs), transient transfection, HMBA increases globin gene expression (Campbell et al.), 1252-1266
TCR 78 gene expression (Carding et al.), 1304-1315
mRNA, TMV 3'-untranslated region (UTR) (Gallie and Walbot), 1149-1157
mRNA decay, bacteriophage T4, role of E. coli RNase E (Mudd et al.), 873-881
mRNA processing, polyadenylation factor Cstf (Takagaki et al.), 2112-2120
mRNA splicing, base-pairing between U2 and U6 snRNA (Hausner et al.), 2146-2156
MRP RNA gene, NRF-1-binding site (Evans and S c a r p u l l a ) , 1023-1034
Mu transposable element, DNA modification in maize (Martienssen et al.), 331-343
Multiallelic gene, U. maydis h mating-type locus (Kronstad and Leong), 1384-1395
Multigene family, NF-El (Yamamoto et aL), 1650-1662
Multisubunit factor Cstf, polyadenylation of mammalian pre-mRNA (Takagaki et al.), 2112-2120
Muscle creatine kinase (MCK) enhancer, af
finity of myogenin-E12 for (Brennan and Olson), 582-595
development Diosophila homeo box gene S59 ex
pression (Dohrmann et al.), 2098-2111
Diosophila nau gene, pattern formation (Michelson et al.), 2086-2097
Diosophila MHC genes, hinge regions (Collier etal.), 885-895
skeletal, and ski oncogene (Sutrave et aL), 1462-1472
Muscle-specific expression, human cardiac actin gene, requirements of (Sartorelli et al.), 1811-1822
Muscle-specific genes, interaction with myogenin-E12 (Brennan and Olson), 582-595
Muscle-specific transcription, and M y o D f a m i l y ( O l s o n ) , 1454-1461 Commentary
Myb oncoprotein, transcriptional regulation (Liischer and Eisenman), 2235-2241 Review
Myc, molecular function (review) (Liischer and Eisenman), 2025-2035
GENES &. DEVELOPMENT 2421
MyoD family, Drosophila nau gene (Mi-chelson et al.), 2086-2097
MyoD gene family and myogenesis (Olson), 1454-1461 Commentary
MyoDl, binding to human cardiac actin g e n e ( S a r t o r e l l i e t a l . ) , 1811-1822
Myogenesis Drosophila nau gene and pattern for
m a t i o n ( M i c h e l s o n et al .) , 2086-2097
quail qmfl expression (de la Brousse and Emerson), 567-581
Myogen ic regu la to ry genes , MyoD family (Olson), 1 4 5 4 - 1 4 6 1 Commentary
Myogenin, sequence-specif ic DNA-binding factor, interaction with muscle-specific genes (Brennan and Olson), 582-595
Myosin heavy chain (MHC) genes, Dio-sophila, alternate hinge regions (Collier et al), 885-895
Myotome formation, quail qmfl mRNA activation (de la Brousse and Emerson), 567-581
Myxococcus xanthus C-factor signaling, cell motili ty re
q u i r e d (Kim a n d K a i s e r ) , 896-904
development-specific factor (Apelian and Inouye), 1396-1403
M-phase-specific, histone HI kinase, ac-tiviation of (Pondaven et al.), 9 -17
N
Nerve growth factor (NGF), regulation of tyrosine hydroxylase gene (TH) (Gizang-Ginsberg and Ziff), 477-491
Neurogenesis, Drosophila characterization of mam (Smoller et
al.), 1688-1700 and Notch locus (Xu et al.), 464-475 sea gene (Mlodzik et al.), 1848-1861
Neurogenic gene, Drosophila Notch locus, interaction with Serrate-gene ( F l e m i n g e t a l . ) , 2188-2201
Neurogen ic locus, Drosophila mam (Smoller et al.), 1688-1700
Neurogenic loci [Drosophila], genetic interactions (Xu et al.), 464-475
Neuronal cells, Drosophila homeo box gene S59 expression (Dohrmann e t a l ) , 098-2111
NF-KB
Tax protein trans-activation (Smith and Greene), 1875-1885
transcription factor, interactions between three subunits of (Urban and Baeuerle), 1975-1984
NF-AT transcription factor, concentration threshold required for tran
scription initiation (Fiering et al.), 1823-1834
NF-El transcription factor, developmen-t a l l y r e g u l a t e d m u l t i g e n e fami ly ( Y a m a m o t o et al.), 1650-1662
nif genes [R. meliloti], in planta, regulat ion of (Sharma and Signer), 344-356
nod genes [R. meliloti], in planta, regulat ion of (Sharma and Signer), 344-356
Notch locus, Drosophila and early neurogenesis (Xu et al.),
464-475 interaction with EGF-containing Ser
rate locus (Fleming et al.), 2188-2201
NRF-1 trans-activator, activation of nuclear respiratory genes (Evans and ScarpuUa), 1023-1034
Nuclear matrix, adenovirus DNA associ-a t i o n ( S c h a a c k e t a l . ) , 1197-1208
Nuclear protein encoded by Drosophila mam neuro
genic locus (Smoller et al.), 1688-1700
encoded by Drosophila runt segment a t i o n gene (Kania et al.), 1701-1713
Nuclear respiratory genes, NRF-1 activation (Evans and Scarpulla), 1023-1034
Nuclear RNA polymerases (eukaryotic), common subunits of (Woychik etal.), 313-323
Nuclear translocation, of ISGF3, regulat ion by IFN (Kessler et al.), 1753-1765
Nut phage X sites, contain boxA transcription signal (Friedman et al.), 2210-2222
O
Octamer sequence, contact points with o c t - 1 ( V e r r i j z e r e t a l . ) , 1964-1974
Octamer-binding proteins, Oct-1 POU i n t e r a c t i o n w i t h HSV TIF (Kristie and Sharp), 2383-2396
Oct-1 (octamer-binding protein), POU-spec i f ic d o m a i n s and POU homeo domain (Verrijzer et al.), 1964-1974
Oct-2, POU homeo-domain prote in , lymphoid-specific gene expression (Elsholz et al.), 43-51
Oligosaccharide antigen, SSEA-1 (Ku-k o w s k a - L a t a l l o e t a l . ) , 1288-1303
O m m a t i d i a l a s s e m b l y , Drosphila (Kimmel et al.), 712-727
Oncogenes myc ( L i i s c h e r a n d E i s e n m a n ) ,
2025-2035 Review
and p53 gene (Lane and Benchimol), 1-8 Review
ski and skeletal muscle growth (Su-traveet al.), 1462-1472
v-erbA, phosphorylation of protein required for function (Glineur et al.), 1663-1676
v-jun and c-jun (Bos et al.), 1677-1687 Oncopro te in , Myb (Liischer and Ei
senman), 2235-2241 Review Orthodenticle [otd] locus, Drosophila,
encodes homeo domain protein necessary for CNS development (Finkelstein et al.), 1516-1527
Ovarian enhancers. See Enhancers
P element integration, Drosophila engrailed region (Hama et al,), 1079-1093
p34cdc2 (dephosphorylated), subunit of active M-phase-specific HIK (Pondaven et al.), 9 -17
p53 gene, oncogene and anti-oncogene (Lane and Benchimol), 1-8 Review
Pair-rule gene, Drosophila runt (Kania et
al), 1701-1713 Pancreas
amylase gene expression in diabetic mice (Keller et al.), 1316-1321
-specific gene expression enhancer reg-u l a t i o n ( N e l s o n e t a l . ) , 1035-1043
X. laevis, changes during metamorp h o s i s (Sh i a n d B r o w n ) , 1107-1113
Pancreatic nuclear protein, PTFl, and amylase gene expression (Keller e t a l ) , 1316-1321
Pattern formation, Drosophila and dpp gene (St. Johnston et al.),
1114-1127 i m a g i n a l d i s k s (Masucc i et al .) ,
2011-2023 muscle development (Michelson et
al.), 2086-2097 sea e x p r e s s i o n (Mlodz ik et al .) ,
1848-1861 Peripheral nervous system, Drosophila
Drosophila development, and Rho gene (Bier et al.), 190-203
sea gene (Mlodzik et al.), 1848-1861 sensory organ development (Block-
linger et al.), 1322-1331 Phage X, termination and antitermina-
t i o n ( F r i e d m a n e t a l . ) , 2210-2222
P h a g e P22 , m u t a n t sar p r o m o t e r ( J a c q u e s a n d S u s s k i n d ) , 1801-1810
Phenotypic screening, of DNA topoiso-m e r a s e I m u t a n t a l l e l e s ( M o r h a m a n d S h u m a n ) , 515-524
2422 GENES & DEVELOPMENT
Pheromone response, yeast, and overproduct ion of STE12 protein (Dolan and Fields), 492-502
Phosphoglycerate kinase-1 (PGK-1) gene, h u m a n X-linked CpG island (Pfeifer et al.), 1277-1287
Phosphorylation, oncogene v-erbA protein product (Glineur et al.), 1663-1676
Photoinduced development, A. nidulans c o n i d i a t i o n s (Mooney and Yager), 1473-1482
Photoreceptor cells, Drosophila compound eye (Fortini and Rubin),
444-463 neuron, chaoptic gene (Pollack et al.),
806-821 sub type spec i f ica t ion and rough
(Kimmel et al.), 712-727 P i tu i t a ry - spec i f i c genes , and POU
homeo domain protein Pit-1 (Elsholz et al.), 43 -51
Pit-1, POU homeo domain protein, pituitary-specific gene expression (Elsholz et al.), 43 -51
Plant pathogen, U. maydis, h locus mul-tiallelic recognition (Kronstad and Leong), 1384-1395
Plant transcription activator, in human s y s t e m ( K a t a g i r i e t a l . ) , 1899-1909
Platelet-derived growth factor (PDGF) gene, dominant-negat ive mut a n t s of ( M e r c o l a et a l . ) , 2333-2341
Ploidy, (altered) mutants, camphor resistant , £. coli (Trun and Got-tesman), 2036-2047
Pole cells, Dwsophila (Lasko and Ash-burner), 905-921
Poly (A) sites, differential site selection, hepa
titis B (Russnak and Ganem), 764-776
removal of maternal mRNAs, oocyte maturation (Vamum and Wor-mington), 2278-2286, (Fox and Wickens), 2287-2298
tail, TMV RNA pseudoknot substitutes for (Gallic and Walbot), 1149-1157
Polyadenylation distance-dependent (cap site to poly(A)
s i te) ( Iwasak i and T e m i n ) , 2299-2307
factor CstF, required for mammalian mRNA processing (Takagaki et al.), 2112-2120
masking proteins (Standart et al.),
2157-2168 stimulated by upstream intron (Niwa
etal.), 1552-1559 Polymerase III promoter element, and
t r a n s c r i p t i o n of y e a s t U6 s n R N A g e n e ( B r o w a n d Guthrie), 1345-1356
Polytene chromosome puffing, Drosophila, and ecdysone hormone ( S e g r a v e s a n d H o g n e s s ) , 204-219
Positional information, Drosophila ima-ginal disk dpp gene (Masucci et al.), 2011-2023
Posterior group genes, Drosophila vasa ( L a s k o a n d A s h b u r n e r ) , 905-921
POU domain of oct-1 binding protein (Verrijzer et
al), 1964-1974 POU-specific box and POU homeo
box of Oct-1 (Kristie and Sharp), 2383-2396
POU homeo domain proteins Pit-1 and Oct-2, binding sites (Elsholz
e t a l ) , 43-51 t ranscr ip t iona l ac t ivators (Baum-
hueter et al.), 372-379 PRDll-BFl DNA binding protein, human
l F N - 3 gene p r o m o t e r , z inc finger motifs of (Fan and Man-iatis), 29 -42
Preinitiation complexes, human, activated by plant DNA-binding p r o t e i n ( K a t a g i r i e t a l . ) , 1899-1909
Preprotachykinin pre-mRNA, alternative splicing of (Nasim et al.), 1172-1184
Prespore gene, Dictyostelium SP60, cAMP regulated (Haberstroh andFirtel), 596-612
Pre-mRNA alternative splicing of (Nasim et al.),
1172-1184 interaction of splicing and polyadeny
la t ion factors (Niwa et al.), 1552-1559
polyadenylation, cleavage-stimulation factor (CstF) (Takagaki et al.), 2112-2120
splicing RNA-protein and protein-protein
interactions (Bordonne et al.), 1185-1196
yeast, role of Ul snRNA (Liao et al.), 1766-1774
Promoters p-globin gene, dominant control re
gion interactions (Antoniou and Grosveld), 1007-1013
BPV-1 PI, repression of by E2 trans-activator (Stenlund and Bot-chan), 123-136
D. melanogaster rhodopsin genes, bipart i te s t ructure (Fortini and Rubin), 444-463
eukaryotic, TATA element replacements (Singer et al.), 636-645
human IFN-p gene, protein binding to regulatory domain (Fan and Maniatis), 29 -42
interaction with terminator, X. laevis
r ibosomal DNA (McStay and Reeder), 1240-1251
recognition, eukaryotic cells (Bell et al), 943-954
Ul snRNA, in vitro transcription init i a t i o n ( G u n d e r s o n et al .) , 2048-2060
Promoter-dependent, transcription elong a t i o n b l o c k a g e of c - m y c (Spencer et al.), 75-88
Protein degradation, intracellular, car-boxy-terminal determinants of (Parsell et al.), 277-286
Prote in-DNA interactions Drosophila su(Hw) p r o t e i n - g y p s y
D N A (Spana and C o r c e s ) , 1505-1515
MyoD, SRF, and Spl with human cardiac actin gene (Sartorelli et al.), 1811-1822
Protein kinase (PKC activators), and Ets2 expression in chicken macrophages (Boulukos et al.), 401-409
Protein kinase A (PKA), cAMP-depen-dent, Dictyostelium developm e n t (Firtel and Chapman) , 18-28
Pro te in l oca l i za t ion , S. cerevisiae C D C 4 6 (F iennessy et a l . ) , 2252-2263
Protein phosphorylation, cell cycle regula ted, and D N A rep l i ca t ion (Salah-ud-Din et al.), 968-977
Protein-protein interactions DNA looping in E. coli gal operon
(Mandal et al.), 410-418 Oct-1/TIF/Cl factor complex (Kristie
and Sharp), 2383-2396 Proteolytic determinants, of lambda re
pressor in E. coli (Parsell et al.), 277-286
Pro to -oncogenes . See also specific names
c-kit, point m u t a t i o n s in W mice (Reith et al.), 390-400
Wnt-l/im-1 (Gavin et al.), 2319-2332 Proto-oncoprotein ets-l, sequence-spe
cif ic D N A - b i n d i n g p r o t e i n (Gunther etal.), 667-679
PRTF factor, yeast, same as GRM factor (Ammerer), 299-312
PSE, of human U l snRNA gene (Gunderson et al.), 2048-2060
Pseudogene segments, chicken VLI donor prefer
e n c e for ( M c C o r m a c k and Thompson), 548-558
Trypanosomes, recombination yields o rde red e x p r e s s i o n of VSG genes (Thon et al.), 1374-1383
Pseudoknots. See RNA pseudoknots Pseudorabies virus, IE protein transcrip
tional activation (Martin et al.), 2376-2382
Pseudo-templated transcription, by E.
GENES & DEVELOPMENT 2423
coli RNA polymerase (Jacques and Susskind), 1801-1810
qmfl, myogenic regulatory gene, expression in quail embryos (de la Brousse and Emerson), 5 6 7 -581
rDNA promoter, frog, half helical turn spacing changes (Pape et al.), 52-61
RecA protein, homologous recombination (Hsieh et al), 1951-1963
R e c o m b i n a s e p ro t e in s , and t r ip le -stranded DNA (Hsieh et al.), 1951-1963
Recombination region-specific, Drosophila engrailed
p r o m o t e r ( H a m a e t a l . ) , 1079-1093
s i te -a l ignment (Tn3 res/resolvase) (Bednarz et al), 2366-2375
Regulatory proteins, hel ix- loop-hel ix group, USF (Gregor et al.), 1730-1740
Regulatory factor RFX, of MHC class II, DNA-binding and dimerization d o m a i n ( R e i t h e t a l . ) , 1528-1540
Regulatory region, positive upstream, human globin genes (Higgs et al.), 1588-1601
Replication factor (RF-A), cell-cycle-regulated phosophorylation (Salah-ud-Din et al.), 968-977
Repression, of enhanson activity, by A2 El A proteins (Rochette-Egly et al.), 137-150
Repressor, of transcription, E2 trans-activator (Stenlund and Botchan), 123-136
Resolution selectivity, Tn3 res recombina t ion s i te (Bednarz et al.), 2366-2375
Resolvase, Tn3 res site alignment (Bednarz et al.), 2366-2375
Retina, Drosophila photoreceptor neurons, chaoptic gene (Pollack et al.), 806-821
Retinoic acid (RA) act ivat ion of X. laevis homeo box
g e n e s ( C h o a n d R o b e r t i s ) , 1910-1916
X. laevis, axis formation alteration (Sive et al), 932-942
Retrotransposon, 412 insertion, Drosophila vermilion
(v) gene (Fridell et al.), 559-566 Drosophila gypsy interaction (Spana
and Corces), 1505-1515 Tyi transposition, specific terminal
s t ructure required (Eichinger and Boeke), 324-330
Retroviral pathogenesis, mouse C-type (Speck et al.), 233-242
Retroviruses, SNV, distance-dependent polyadenylation (Iwasaki and Temin), 2299-2307
Rev prote in , HIV-1 (Ahmed et al.), 1014-1022
interaction with RRE RNA (Olsen et al.), 1357-1364
Reverse transcription t r a n s c r i p t i o n h e p a t i t i s B v i ruses
(Russnak and Ganem), 764-776 and yeast Tyl transposition (Eichinger
and Boeke), 324-330 Rex protein, HTLV-1 (Ahmed et al.),
1014-1022 Rhizobium meliloti, symbiotic genes, in
planta, regulation of (Sharma and Signer ), 344-356
Rhodopsin genes [Drosophila melano-gaster], b i p a r t i t e p r o m o t e r structure (Fortini and Rubin), 444-463
Rhomboid (Rho), Drosophila gene, dor-soventral axis es tabl ishment and PNS development (Bier et al), 190-203
Rhombomeres, chick hindbrain segmenta t ion (Sundin and Eichele), 1267-1276
R ibonuc l ea se E, degrada t ion of T4 mRNA (Mudd et al), 873-881
Ribonucleotide reductase, regulatory subunits of (Elledge and Davis), 740-751
R i b o n u c l e o t i d e r e d u c t a s e m R N A , masked message in clam ooc y t e s ( S t a n d a r t e t a l . ) , 2157-2168
Ribosomal genes, RNA 3'-end formation and transcription termination are separable events (Labhart and Reeder), 269-276
Ribosomal internal entry, translation of E M C V m R N A ( J a n g a n d Wimmer), 1560-1572
RNA -binding protein, involvement in cap-
i n d e p e n d e n t t r a n s l a t i o n of EMCV (Jang and Wimmer ) , 1560-1572
3'-end formation in X. laevis (Labhart and Reeder), 169-176
localization, subcellular chaoptic gene (Pollack et al.), 806-821
pol 1, species specific recognition (Bell et al.), 943-954
polymerase p-subunit (£. coli], t ranscript ion
pausing and termination (Lan-d i c k e t a l ) , 1623-1636
E. coh, pseudo-templated transcript ion (Jacques and Susskind) 1801-1810
eukaryotic, common subuni ts of (Woychiketal.), 313-323
polymerase I eukaryot ic , t r anscr ip t iona l ma
chinery (Pape et al.), 52 -61 X. laevis, terminator-promoter in
teraction (McStay and Reeder), 1240-1251
polymerase 11, orientation dependent recogni t ion of AD IVa2 promoter initiator (Carcamo et al.), 1611-1622
polymerase 111 inhibition by Sarkosyl (Kovelman
and Roeder), 646-658 and U6 snRNA gene expression
(Brow and Guthrie), 1345-1356 yeast , t r ansc r ip t iona l in i t i a t ion
(Singer et al.), 636-645 processing, and 3'-end formation in X.
laevis (Labhart and Reeder), 269-276
pseudoknot , TMV, subs t i t u t e s for poly(A) tail (Gallic and Walbot), 1149-1157
response elements, HTLV-1 Rex and HlV-1 Rev (Ahmed et al .) , 1014-1022
secondary s t ruc tu re , and RNA response elements (Ahmed et al.), 1014-1022
short transcript synthesis by HIV-1 LTR (Ratnasabapathy et al.), 2061-2074
splicing alternative, Drosophila MHC genes
(Collier et al.), 885-895 Drosophila dsx gene, sex-specific
patterns and cis-acting mutations (Nagoshi and Baker),89-110
SF2 spl icing factor, pur i f icat ion from HeLa cells (Krainer et al.), 1158-1171
3 ' splice site selection (Mitchel et al), 777-788
s t a b i l i t y , X. laevis h o m e o box Xlhbox2 m R N A (Brown and Richard), 1925-1935
U2, secondary structure (Hartshome and Agabian), 2121-2131
RNase Ill-dependent hydrolysis, of Xcll-O mRNA (Krinke and Wulff), 2223-2233
Rough expression, and Drosophila eye deve lopment (Basler et al.), 7 2 8 - 7 3 9 , ( K i m m e l et a l . j , 712-727
Rous sarcoma virus (RSV), transcription f rom LTR ( D u t t a e t a l . ) , 243-254
RPB5, 6, and 8, RNA subunit genes, isolation and characterization of (Woychik et al.), 313-323
rpob gene, E. coli, termination-altering m u t a t i o n s (Landick et al.), 1623-1636
RRE RNA, interaction with HIV-1 Rev
2424 GENES & DEVELOPMENT
p r o t e i n ( O l s e n e t a l . ) , 1357-1364
rRNA transcription, and multiprotein complex (Bell et al), 943-954
Runt segmentation gene, Diosophila, s e q u e n c e and d i s t r i b u t i o n (Kania et al.), 1701-1713
S59 homeo box gene, Diosophila, expression in mesoderm, CNS, and midgut (Dohrmarm et al.), 2098-2111
Saccharomyces ceievisiae. See also Yeast
CDC46 prote in local iza t ion (Hen-nessy et al.), 2252-2263
genes (DlTl and DIT2) required for spore wall formation (Briza et al.), 1775-1789
HAP2/3/4 CCAAT transcriptional activation complex (Olesen and Guarente), 1714-1729
human CKSl homologs (Richardson et al), 1332-1344
histone synthesis, balancing (Moran et al), 752-763
mating response pathway, STEII gene (Rhodes et al.), 1862-1874
RPB5, 6 and 8 genes, encode RNA polymerase common subunits (Woychik et al.), 313-323
STE12 overproduction and transcript iona l induc t ion (Dolan and Fields), 492-502
TATA element replacement (Singer et al.), 636-645
TFIID functional domain conserved in S. pombe (Hoffmann et al.), 1141-1148
Tyl t r a n s p o s i t i o n (Eichinger and Boeke), 324-330
U l snRNA m u t a t i o n (Liao et al.), 1766-1774
U6 and U4 snRNA (Madhani et al), 2264-2277
U6 snRNA gene expression (Brow and Guthrie), 1345-1356
Sarkosyl, RNA polymerase III initiation ( K o v e l m a n a n d R o e d e r ) , 646-658
Scabrous gene, Diosophila neurogenesis (Mlodzik et al.), 1848-1861
Schizosaccharomyces pombe sucl+ (Richardson et al.), 1332-1344 TFIID functional domain, homology
to S. ceievisiae (Hoffmann et al.), 1141-1148
Sea urchin. See also Stiongylocentiotus puipuiatus
embryos, intersecting gene batteries (Thiebaud et al.), 1999-2010
TSAP, mammmalian homolog BSAP (Barberis et al.), 849-859
Secondary structure, U2 RNA (Hart-
s h o r n e a n d A g a b i a n ) , 2121-2131
Segment polarity gene, Diosophila cP (Orenic et al.), 1053-1067 en gene, control of stripes (Kassis),
433-443 Segmental identity, Diosophila, affected
by exd gene (Peifer and Wies-chaus), 1209-1223
Segmentation gene, Diosophila. See also specific genes
ftz, transcriptional activator of (Ueda et al), 624-635
ftz stability mutants (Kellerman et al.), 1936-1950
lunt sequence and distribution (Kania etal.), 1701-1713
Segmentation, chick hindbrain (Sundin andEichele), 1267-1276
Sensory organ development, Diosophila cut locus (Blocklinger et al.), 1322-1331
Sequence conservat ion, TFIID functional domain, S. ceievisiae and S. pombe (Hoffmann et al.), 1141-1148
Serendipity alpha (srya) gene, Diosophila, role in blastoderm cellu-larization (Schweisguth et al.), 922-931
Senate gene, Diosophila EGF-con-taining locus (Fleming et al.), 2188-2201
Serum, increased CCAAT-binding factor level (Dutta et al.), 243-254
Serum a lbumin gene, ac t iva t ion by C / E B P ( F r i e d m a n a n d McKnight), 1416-1426
Serum induction, of PRDII-BFl mRNA (Fan and Maniatis), 29-42
Serum response element (SRE), and c-/os transcriptional regulation (Rivera et al.), 255-268
Serum response factor (SRF) binding to human cardiac a-actin gene
(Sartorelli et al), 1811-1822 CKIl e n h a n c e s D N A b i n d i n g of
(Manak et al.), 955-967 Sevenless gene, and Diosophila lough
e x p r e s s i o n (Eas ie r e t a l . ) , 7 2 8 - 7 3 9 , (K immel et al .) , 712-727
Sex determination, Diosophila Diosophila dsx mutations and disrup
tion of RNA processing (Na-goshi and Baker), 89-110
tra-2 gene (Mattox et al.), 789-805 SF2 splicing factor, purification from
HeLa cel ls (Krainer et al.), 1158-1171
SH2 m u t a n t s , of c-src (Hira i and Varmus), 2342-2352
Sigma^^, E. coli, concentration regulated by heat shock proteins (Strauss et al.), 2202-2209
Sigma factors
Bacillus subtihs sigma* and sporula-tion (Kimkel et al.), 525-535
M. xanthus, development-specif ic ( A p e l i a n a n d I n o u y e ) , 1396-1403
Signal transduction systems, bacterial similarity to B. subtilis regulatory gene (Weinrauch et al.), 860-872
Signal transduction c A M P - m e d i a t e d ( W e i t h e t a l . ) ,
1437-1449 I F N - a s y s t e m ( K e s s l e r e t a l . ) ,
1753-1765 M. xanthus C-factor transmission re
quires cell motil i ty (Kim and Kaiser), 896-904
mice, by transmembrane protein tyros ine k ina se s (Rei th et al.), 390-400
yeast STEII protein kinase (Rhodes et al.), 1862-1874
Signaling peptides, mouse Wnt-l/int-1-related gene family (Gavin et al.), 2319-2332
Site-specific recombination, Tn3 res/re-s o l v a s e ( B e d n a r z e t a l . ) ; 2366-2375
Skeletal muscle growth, and ski oncogene (Sutrave et al.), 1462-1472
ski oncogene , and ske l e t a l m u s c l e g r o w t h ( S u t r a v e e t a l . ) , 1462-1472
Slit protein, Diosophila midline glia development and axon pathways (Rothenberg et al.), 2169-2187
Sm proteins, interaction with snRNAs (Bordonne et al.), 1185-1196
snRNA, base-pairing between U2 and U6 (Hausner et al.). 2146-2156
snRNPs, S. ceievisiae, in vivo assembly (Bordonne et al.), 1185-1196
Somites, developmental expression of q u a i l qmfl m R N A (de la Brousse and Emerson), 567-581
Spl binding to human cardiac a-actin gene
(SartoreUi et al.), 1811-1822 transcription fator, SV40 activation of
(Saffer et al.), 659-666 SP60 spore coat protein, Dictyostehum,
cis-acting regulatory regions of ( H a b e r s t r o h a n d F i r t e l ) , 596-612
Spec3 (S. puipuiatus] protein localization, cilia and Golgi complexes of embryoriic ectoderm (Eldon etal.), 111-122
Species selectivity, and rDNA transcription (Pape et al.), 52-61
Spermatogenesis , express ion of Zfy genes (Nagamine et al.), 63 -74
Spleen necrosis virus (SNV), distance-dependent polyadenylation (Iwa-saki and Temin), 2299-2307
Splice site selection, and al ternat ive
GENES & DEVELOPMENT 2425
splicing of pre-mRNA (Nasim etal.), 1172-1184
Spliceosome assembly, SF2 splicing factor (Krainer
etal.), 1158-1171 snRNA base-pairing interactions
(Hausner et al.), 2146-2156 Splicing
apparatus, eukaryotic cells, and snRNA (Ares and Igel), 2132-2145
Diosophila retrotransposon from exon (Fridell et al.), 559-566
factor, SF2, purification from HeLa cells (Krainer et al), 1158-1171
interaction with polyadenylation (Niwaetal.), 1552-1559
RNA-protein and protein-protein interactions (Bordonne et al.), 1185-1196
S. ceievisiae, multiple roles for U6 snRNA (Madhani et al.), 2264-2277
tians and cis systems (Hartshome and Agabian), 2121-2131
Sporulation Bacillus subtilis, and sigma^ tran
scription factor (Kunkel et al.), 525-535
role of B. subtilis regulatory gene product (Weinrauch et al.), 860-872
S. cerevisiae, spore wall maturation (Briza et al.), 1775-1789
Stage-specific embryonic antigen jSSEA-1), murine, cell-surface oligosaccharide (Kukowska-Latallo etal.), 1288-1303
STE12 yeast protein, overproduction yields increased transcription from pheromone-inducible genes (Dolan and Fields), 492-502
STEII protein kinase, yeast, cell-type-specific transcription and signal transduction (Rhodes et al.), 1862-1874
Stem cells, hematopoiesis in mice (Jordan and Lemischka) , 220-232
Stem cell differentiation, control by DIA/LIF (Rathjen et al.), 2308-2318
Stem-loop structure, snRNA (Ares and Igel), 2132-2145
Steroid hormone, ecdysone, and Dioso-hila polytene chromosome puffing (Segraves and Hogness), 204-219
Steroid hormone receptor, Diosophila CFl transcription factor (Shea etal.), 1128-1140
Steroid receptor superfamily and Diosophila E75 proteins (Segraves
and Hogness), 204-219 HNF-4 transcription factor (Sladek et
al), 2353-2365
Stiongylocentiotus puipuiatus, Spec3 protein localization (Eldon et al.), 111-122
SunY intron, bacteriophage T4 (Mitchel etal.), 777-788
Suppressible mutation (hcfl06), induced by Robertson's Mutator in maize (Martienssen et al.), 331-343
Suppression, of Diosophila veimilion (v) gene alleles (Fridell et al.), 559-566
SV40 activation of Spl (Saffer et al.),
659-666 enhancer, repression by ElA gene
products (Rochette-Egly et al.), 137-150
large-T antigen and p53 binding (Lane and Benchimol), 1-8 Review
late promoter, binding of transcription factor LSF (Huang et al.), 287-298
Symbiotic genes {R. meliloti), in planta, regulation of (Sharma and Signer), 344-356
Synergy between trans-activators (Tat and ElA), regulation of HlV-1 gene expression (Laspia et al.), 2397-2408
T antigen, SV40, alteration of Spl activity at mRNA level (Saffer et al.), 659-666
T cells, human, gene targeting at CD4 locus (Jasin et al.), 157-166
T lymphocytes, activation (Fiering et al.), 1823-1834
TAR element, and Tat trans-activation (Ra tnasabapa thy et al.) , 2061-2074
TAR RNA sequence, HlV-1, Tat binding (Roy etal.), 1365-1373
TAT gene, transcription and cAMP-stimulated protein binding (Weith et al.), 1437-1449
Tat protein binding to HlV-1 TAR RNA (Roy et
al.), 1365-1373 trans-activation via TAR, HIV-l gene
expression (Ratnasabapathy et al.), 2061-2074
Tat trans-activator, regulation of HIV-l gene expression (Laspia et al.), 2397-2408
TATA box, TFIID (5. ceievisiae and S. pombe] binding (Hoffmann et al.), 1141-1148
TATA element, yeast, replacement of and transcriptional initiation (Singer et al.), 636-645
TATA motif, and TFIID-dependent transcription from AD IVa2 prom o t e r (Carcamo et a l . ) , 1611-1622
Tax gene, HTLV-1, mutants of (Smith and Greene), 1875-1885
Temporal specificity, of globin gene ex-p r e s s i o n , and HS s i t e s (Behringer et al.), 380-389
Termination elements, X laevis, ribo-somal genes (McStay and Reeder), 1240-1251
Termination signal, phage X boxA (Friedman et al.), 2210-2222
Testis determination, candidate Y genes [Zfy-l and Zfy-2] expression in mice (Nagamine et al.), 63-74
TFE3. See Transcription factor E3 TFIIA, Xenopus, synthesis in somatic
cells vs oocytes (Kim et al.), 1602-1610
TFIID S. ceievisiae, functional domain con
served in S. pombe (Hoffmann etal.), 1141-1148
TATA-binding protein, involvement in transcription from Ad IVa2 promoter (Carcamo et a l ) , 1611-1622
TGAla, tobacco DNA-binding protein, and transcription activation mechanism (Katagiri et al.), 1899-1909
TGF-p family, secreted protein product encoded by Diosophila dpp gene (St. Johnston et al.), 1114-1127
Thymic development, TCR yb gene ex-press ion (Carding et al.), 1304-1315
Thyroid hormone (TH) receptor genes, correlation of expres
sion with amphibian metamorphosis (Yaoita and Brown), 1917-1924
X. laevis, pancreatic gene regulation (Shi and Brown), 1107-1113
Thy-1/CD4 gene fusion, and homologous recombination (Jasin et al.), 157-166
TIMP gene, mouse, developmental expression (Flenniken and Williams), 1094-1106
Tissue inhibitor of metalloproteins. See TIMP
Tissue-specific expression, human cardiac a-actin gene, requirements of (SartoreUi et al.), 1811-1822
Tn3 res recombination site, resolvase binding sites (Bednarz et al.), 2366-2375
Tobacco mosaic virus, 3'-untranslated region (UTR) (Gallie and Walbot), 1149-1157
Topoisomerase I, DNA, mutant alleles of (Morham and Shuman), 515-524
Trans-acting factor GBF, and cAMP-in-ducible Dictyostelium genes (Hjorth et al.), 419-432
Trans-activation
2426 GENES & DEVELOPMENT
HTLV-1 Tax p ro t e in (Smith and Greene), 1875-1885
HTLV-1 Tat-mediated (Roy et al.), 1365-1373
by NF-El multigene family (Yama-m o t o e t al.), 1650-1662
of se rum a lbumin gene by C/EBP ( F r i e d m a n and M c K n i g h t ) , 1416-1426
Trans-activator NRF-1, activation of nuclear respira
tory genes (Evans and Scar-puUa), 1023-1034
synergy between HIV-1 Tat and Ad ElA (Laspia et al), 2397-2408
Transcription activation of human cardiac a-actin
g e n e ( S a r t o r e l l i e t a l . ) , 1811-1822
activation mechanism, plant activator in human system (Katagiri et al.), 1899-1909
balanced synthesis of histone locus (Moran et al), 752-763
developmental ly regulated, Droso-phila Fos related AP-1 (Perkins et al.), 822-834
E3, binding specificity for (jiE3 site of IgH enhancer (Beckmann et al.), 167-179
elongation, promoter-dependent block of c-myc (Spencer et al.), 75-88
gal operon (£. coli], repression of and DNA looping (Mandal et al.), 410-418
HeLa LSF, b inds t w o SV40 s i tes (Huang et al.), 287-298
HNF-1, broadly acting homeo domain prote in (Baumhueter et al.), 372-379
in i t i a t ion , funct ional downs t ream TATA motif (Carcamo et al.), 1611-1622
in v i t ro in i t i a t ion , of U l snRNA (Gunderson et al.), 2048-2060
keratinocyte-specific gene expression (Leask et al), 1985-1998
from LTR of RSV (Dut ta et al.), 243-254
pseudo-templated, by E. coli RNA polymerase (Jacques and Suss-kind), 1801-1810
role of RNA polymerase subun i t s (Woychik et al.), 313-323
t e r m i n a t i o n and an t i t e rmina t ion , phage X. (F r i edman et al .) , 2210-2222
termination and pausing, altered by mutations in E. coli rpob gene (Landick et al), 1623-1636
Transcr ipt ion factors. See also individual names
Transcription factor AP-4 dimerization domains (Hu et al.),
1741-1752 B-cell lineage-specific (BSAP), TSAP
m a m m m a l i a n homolog (Bar-beris et al.), 849-859
concentration threshold required for transcription initiation (Fiering etal.), 1823-1834
Drosophila, CFl and CF2 bind to s l5 chorion promoter (Shea et al.), 1128-1140
HNF-4, novel steroid receptor family m e m b e r ( S l a d e k e t a l . ) , 2353-2365
m e c h a n i s m s (Berk and Schmidt ) , 151-155 Meeting Review
NF-KB (Hagman et al.), 978-992 N F - K B , subunit interactions (Urban
and Baeuerle), 1975-1984 oct-1 binding to octamer sequence
(Verrijzer et al.), 1964-1974 PSEl of U l snRNA promoter (Gun
derson et al.), 2048-2060 Spl, SV40 activation of (Saffer et al.),
659-666 SRF enhanced DNA binding (Manak
et al.), 955-967 TFIIIC and TFIIIB (Brow and Guthrie),
1341-1356 tissue-specific expression of NF-El
multigene family (Yamamoto et al.), 1650-1662
spec ie s spec i f i c i t y (Bell et al .) , 943-954
Transcription initiation RNA polymerase III, mhib i t ion by
S a r k o s y l ( K o v e l m a n a n d Roeder), 646-658
TFIID, S. cerevisiae and S. pombe sequence conservation (Hoffmann e t a l ) , 1141-1148
Transcription termination mechanism of in X. laevis (Labhart
and Reeder), 269-276 RNA polymerase I, te rminator-pro
moter interaction (McStay and Reeder), 1240-1251
Transcriptional activation complex, yeast HAP2/3/4 CCAAT
( O l e s e n a n d G u a r e n t e ) , 1714-1729
byLAP(Descombesetal .) , 1541-1551 by pseudorab ies v i rus IE p ro te in
(Martin et al.), 2376-2382 and TATA e l e m e n t r e p l a c e m e n t
(Singer et al.), 636-645 t h r e s h o l d e v e n t (Fier ing et al . ) ,
1823-1834 Transcriptional activator
erythroid factor GF-1 (NF-El/Eryf 1) (Martin and Orkin), 1886-1898
ets-l (Gunther et al.), 667-679 mul t imer ic , ISGF3 (Kessler et al.),
1753-1765 Transcriptional control, cell-specific reg
ulation of HNF-3A (Lai et al.), 1427-1436
Transcriptional elongation, stabilization causes HlV-l Ta t -Ad ElA syn
ergy (Laspia et al.), 2397-2408 Transcriptional induction, yeast, and
STE12 overproduction (Dolan and Fields), 492-502
Transcriptional regulation c A M P - m e d i a t e d (Wei th et a l . ) ,
1437-1449 Myb oncoprotein (Luscher and Ei-
senmanj, 2235-2241 Review Transcriptional repression
of C-/OS (Rivera et al.), 255-268 by E2 trans-activator on BPV-1 PI pro
moter (Stenlund and Botchan), 123-136
Transcriptional stimulation, in vitro, by Drosophila UBX (Johnson and Krasnow), 1044-1052
Transformation c-Jun and v-Jun (Bos et al.), 1677-1687 by SIC (Hirai and Varmus), 2342-2352
TiansfoTmeT-2 [tia-2] gene, Drosophila, alternative splicing (Mattox et al.), 789-805
Trans fo rming g rowth fac tor -p . See
TGF-p Transgenic Drosophila
constructs, engrailed-lacZ (Hama et al.), 1079-1093
en/lacZ fusion genes, control of en stripes (Kassis), 433-443
Transgenic mice globin (human), gene switching in
(Behringer et al.), 380-389 human a-globin genes and regulatory
region (Higgs et al.), 1588-1601 and insulin function (Keller et al.),
1316-1321 ski expression and skeletal muscle
(Sutrave et al), 1462-1472 T I M P - i a c Z fusion gene (Flenniken
and Williams), 1094-1106 Translation
cap-independent translation of EMCV (Jang and Wimmer), 1560-1572
E. coli, in i t i a to r tRNA, in i t i a t ion codon, and IF3 (Hartz et al.), 1790-1800
Translational activation, masked ma-temal mRNA (Standart et al.), 2157-2168
Translational efficiency, and nonpolya-denylated mRNAs (Gallic and Walbot), 1149-1157
Translational regulation poly(A) removal during Xenopus oo
c y t e m a t u r a t i o n (Fox and Wickens), 2287-2298
poly(A) removal during Xenopus oocyte maturat ion (Varnum and Wormington), 2278-2286
Transmembrane receptor c-kit (W mutant mice), point mutations in kinase domains of (Reith et al.), 390-400
Transposable element, DNA modificat i on of Mu in ma ize (Mar-
GENES & DEVELOPMENT 2427
tienssen et al.), 331-343 Transposition, of yeast Tyl retrotran-
sposon (Eichinger and Boeke), 324-330
Transposon fusions, Tn5-gusA promoter/probe construct and R. meliloti gene r egu l a t i on (Sharma and Signer), 344-356
Transposon mutagenesis. Antirrhinum majus floral development (Carpenter and Coen), 1483-1493
Transthyretin (TTR) gene, and HNF-4-binding activity (Sladek et al.), 2353-2365
tRNA, E. coli translation initiation (Hartz et al.), 1790-1800
Trypanosomatids, secondary structure of U2 RNAs (Hartshome and Agabian), 2121-2131
Trypanosome, VSG genes, ordered expression of (Thon et al.), 1374-1383
Trypsin, X. laevis, developmental and thyroxine-dependent regulation of (Shi and Brown), 1107-1113
Tyrosine kinase c-ldt, point mutations in W mice (Reith et al.), 390-400
Tyrosine hydroxylase (TH) gene, regulation of by nerve growth factor (NGF) (Gizang-Ginsberg and Ziff), 477-491
T-cell receptor (TCR), 78 gene expression (Carding et al.), 1304-1315
U
Ul snRNA promoter, in vitro transcription initiation (Gunderson et al.), 2048-2060
Ul snRNA sequences, yeast, contribution to Ul snRNP function (Liaoetal.), 1766-1774
U2 RNA, secondary structure (Hart-s h o r n e a n d A g a b i a n ) , 2121-2131
U2 snRNA, stem-loop structures (Ares and Igel), 2132-2145
U4 snRNA, S. cerevisiae, association with U6 snRNA (Madhani et al.), 2264-2277
U6 snRNA gene expression, B block pro-moter e lement (Brow and Guthrie), 1345-1356
U6 snRNA, S. cerevisiac,multiple roles of (Madhani et al.), 2264-2277
U A S Q (GAL upstream activating sequence), chromatin structure of influenced by GRF2 yeast protein (Chasman et al.), 503-514
UBF-SLl complexes, and rRNA promoter selectivity (Bell et al.), 943-954
UBX protein, Diosophila, transcriptional stimulation in vitro
( [ohnson and Krasnow) , 1044-1052
Ultiabithorax [Ubx], Diosophila, similarity to abdA (Karch et al.), 1573-1587
USF regulatory protein, c-myc-related with helix-loop-helix domain (Gregor et al.), 1730-1740
Ustilago maydis, plant pathogen, b locus multiallelic recombination (Kronstad and Leong), 1384-1395
v-erbA oncogene, phosphorylation of protein required for function (Glineur et al.), 1663-1676
v-Jun, as compared to c-Jun in inducing cell transformation (Bos et al.), 1677-1687
v-src, increase CCAAT-binding factor level (Dutta et al.), 243-254
VAi adenovirus gene, ElA-mediated transcriptional initiation (Ko-velman and Roeder), 646-658
Vaccinia topoisomerase, genetic screen for mutan t s (Morham and Shuman), 515-524
Variable surface glycoproteins (VSGs), Trypanosome, ordered expression of (Thon et al.), 1374-1383
Vasa maternal-effect gene, posterior localization (Lasko and Ash-bumer), 905-921
Virus induction, of PRDII-BFl mRNA (Fan and Maniatis), 29-42
Vulval development, C. elegans Un-lO gene (Kim and Horv i tz ) , 357-371
W
W locus (mice), and c-kit point mutation (Reith et al.), 390-400
Wnt-l/int-l-related gene family, fetal and adult mouse development (Gavin etal.), 2319-2332
Xenopus laevis deadenylation of maternal mRNAs
(Varnum and Wormington), 2278-2286
dominant-negative mutant of PDGF g e n e ( M e r c o l a e t a l . ) , 2333-2341
homeo box gene activation (Cho and Robertis), 1910-1916
homeo box Xlhbox2 mRNA stability ( B r o w n a n d R i c h a r d ) , 1925-1935
metamorphosis and thyroid hormone receptor gene expression (Yaoita and Brown), 1917-1924
oocytes, deadenylation of maternal mRNAs (Fox and Wickens), 2287-2298
pancreatic gene regulation (Shi and Brown), 1107-1113
primary axis formation, RA-sensitive period (Sive et al.), 932-942
ribosomal genes, transcription termination mechanism (Labhart and Reeder), 269-276
RNA polymerase I, terminator-promoter interaction (McStay and Reeder), 1240-1251
TFIIIA synthesis, somatic cells and oocytes (Kim et al.), 1602-1610
X-linked gene, human PGK-1, CpG island (Pfeifer et al.), 1277-1287
Yeast, PRTF/GRM, purification and cloning (Ammerer), 299-312. See also Saccharomyces cerevisiae
Yolk protein genes (ypl and yp2), Droso-phila, ovarian enhancers of (Logan and Wensink), 613-623
Zfy genes, candidate testis-determining Y genes, expression in mice (Nagamine et al.), 63-74
Zinc finger domain steroid receptor superfamily (Sladek et
al.), 2353-2365 Tax protein, nuclear localization
(Smith and Greene), 1875-1885 Zinc finger motifs, of PRDII-BFl DNA
binding protein (Fan and Man-iaris), 29-42
Zinc finger protein C2H2 family, Diosophila CF2 tran
scription factor (Shea et al.), 1128-1140
DNA bending and binding specificity (Spana and Corces), 1505-1515
Diosophila segmentation ci' protein sequence similarity (Orenic et aL), 1053-1067
encoded by testis determining Zfy-1 and Zfy-2 genes (Nagamine et aL), 63-74
TFEA synthesis in Xenopus (Kim et aL), 1602-1610
Zygotic genes, Drosophila en gene, control of stripes (Kassis), 433-443
Zygotic dorsoventral genes, Rho, and Drosophila neural development (Bier et al.), 190-203
2428 GENES & DEVELOPMENT
Cold Spring Harbor Laboratory 1991 Meeting Schedule
THE ROLE OF ISOFORM DIVERSITY IN CYTOSKELETAL FUNCTIONS, AprU 24 - 28
Henry Epstein, Baylor College of Medicine Donald Fischman, Cornell University David Helfman, Cold Spring Harbor Laboratory
STRESS PROTEINS & THE HEAT SHOCK RESPONSE April 29 - May 2
Costa Georgopoulos, University of Utah Richnrd Morimoto, Northwestern University
GENOME MAPPING & SEQUENCING, May 8 -12 Charles Cantor, DOE, Human Genome Project Maynard Olson, Washington University School of Medicine Richard Roberts, Cold Spring Harbor Laboratory
RNA PROCESSING, May 15 -19 Chris Greer, University of California, Irvine James Manley, Columbia University Alan Weiner, Yale University School of Medicine
RNA TUMOR VIRUSES, May 21 - 26 John Coffin, Tufts University School of Medicine Irvin Chen, University of California, Los Angeles
SYMPOSIUM: THE CELL CYCLE, May 29 - June 5 David Beach, Cold Spring Harbor Laboratory Bruce Stillman, Cold Spring Harbor Laboratory
James D. Watson, Cold Spring Harbor Laboratory YEAST CELL BIOLOGY, August 14 -18
John Pringle, University of Michigan Steven Reed, Scripps Clinic & Research Foundation
MOLECULAR GENETICS OF BACTERIA & PHAGES August 20 • 25
Susan Gottesman, National Institutes of Health, NIH Lucia Rothman-Denes, University of Chicago Mimi Susskind, University of Southern California
REGULATION OF EUKARYOTIC mRNA TRANSCRIPTION August 28 - September 1
Winship Herr, Cold Spring Harbor Laboratory Robert Tjian, University of California, Berkeley Keith Yamamoto, University of California, San Francisco
EUKARYOTIC DNA REPUCATION, September 4 - 8 Thomas Kelly, Johns Hopkins University Bruce Stillman, Cold Spring Harbor Laboratory
SYNTHESIS OF RIBOSOMES, September 11-15 Lasse Lindahl, University of Rochester Edward Morgan, Roswell Park Memorial Institute Robert Perry, Fox Chase Cancer Center Barbara Sollner-Webb, Johns Hopkins University Jonathan Warner, Albert Einstein College of Medicine
MODERN APPROACHES TO NEW VACCINES INCLUDING PREVENTION OF AIDS, September 19 - 23
Frederick Brown, University of Surrey Robert Chanock, National Institutes of Health, NIAID Harold Ginsberg, Columbia University College ofP&S Richard Lemer, Research Institute of Scripps Clinic
MOLECULAR NEUROBIOLOGY OF DROSOPHILA September 25 - 29
Ralph Greenspan, Roche Institute of Molecular Biology John Palka, University of Washington
MOLECULAR BIOLOGY OF SIGNAL TRANSDUCTION IN PLANTS, October 2 - 6
Frederick Ausubel, Whitehead Institute Nam-Hai Chua, The Rockefeller University Gerald Fink, Whitehead Institute Venkatesan Sundaresan, Cold Spring Harbor Laboratory
FOR INFORMATION AND APPUCATIONS WRITE TO: %"»o '% MEETINGS OFFICE
r-c\ \ COLD SPRING HARBOR LABORATORY L b r l j j COLD SPRING HARBOR, NY 11724
^EN i '' 516-367-834€ FAX-516-367-8846
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ICN Radiochemicals Division of ICN Biomedicals, Inc. P.O. Box 19536 Irvine, CA 92713 (800) 854-0530
Now available from ICN Biomedicals, Inc., Chloramphenicol, D-threo-[1.2-'' C] for monitoring promoter activity in promoter CAT fusion.
Chloramphenicol Is a substrate for the bacterial enzyme Chloramphenicol Acetyltransferose (CAT). Quantitation of the acetylated product has become a standard measurement of promoter activity in transfected mammalian cells of promoter sequences linked to the CAT gene.
Reader Service No. 530