2
Review of Evidence: Ayurvedic Practices for PT Andrea Lopasso, DPT, Dr. Beth Phillips, PT, DPA, Woody Somvichai, DPT, Shayan Safar, DPT, Bret Maddux, DPT, Nash Weinberg, DPT Department of Physical Therapy Introduction Physical therapist (PT) spend more time with patients than most health care providers allowing the time to educate patients about Complementary Integrative Therapies (CIT) and provide nutritional guidance towards healthy, often more cost-effective, treatment and prevention options with longer lasting results. As PTs in CA, we are legally allowed to give nutritional advice and APTA supports the use of evidence based CIT practices. Therefore this study delved into understanding the complexity of Ayurvedic Medicine and herbal physiological effects with applications to physical therapy. Ayurveda Practiced > 10,000 years Meaning: Life knowledge - healthy way of being Primary aim: prevent disease Holistic: focus on physical, emotional & spiritual health Objective: Guidance toward individual’s control of own health Align lifestyle/nutritional habits to seasons/cycles of nature Emphasis: proper digestion, assimilation & elimination proper diet in accordance with individual’s Dosha: physical/mental elements of Fire/”pita” – Wind/”vata” – Earth & Water/”Kapha” and time of day & year Component of “YOGA” Traditionally includes Ayurveda, meditation, asanas In Western world reduced to physical exercise Turmeric Purpose “The American Physical Therapy Association supports the continued use of evidence-based complementary and Integrative interventions in physical therapy practice.” Therefore, the relevance of this investigation of evidence is to bring Awareness and knowledge of other forms of therapies from which our patients can benefit. PTs are well positioned to bridge the east-west science gap. Patients/health care consumers are seeking alternatives that are: Cost efficient Safer for pain control to ↓ opioid epidemic Reduce excessive use of medications as people become more aware of the negative side-effects Ashwagandha Diabetes and Ayurveda Conclusion Due to the holistic nature of Ayurveda, the empirical reductionist research model that tends to isolate variables often cannot capture the magnitude of beneficial results found in the relationships of the many Ayurvedic variables and their synergistic effects. However, research shows strong evidence for herbal supplementation and its health benefits, many of which are directly applicable to PT, and all of which could be beneficial to our patient’s overall health and wellbeing. DPT curricula could be enriched by providing information on a variety of complimentary integrative therapies including Ayurveda as part of wellness and prevention and for additional referral options to benefit patients. Scope of Practice: California Practice Act allows giving nutritional advice as long as Chapter 5 Article 3 is posted at the clinic. https://www.ptbc.ca.gov/forms/law_reference_guide.pdf Strongest evidence: Modulates Anti-inflammatory Cytokines Decreases muscle pain post-exercise Improves muscle performance 1g as effective as pain medicine for arthritis decreasing PVAS Oregano Strongest evidence: Antibacterial, antiviral and antimicrobial dosage 2.0-2.5 μg/ml concentration Anti-inflammatory decreases inflammatory cytokines increases anti-inflammatory cytokines dosage 35-70 μg/ml concentration Anti-nociception extremely high doses needed up to 100 mg/Kg body weight Strongest evidence: Powerful adaptogen (↓ stress levels) Increases muscle strength and size Speeds up muscle recovery Prevents proliferative growth of tumors Promotes memory and mental capacity Protects from neurodegenerative disease Reduces biomarkers of clinical anxiety in the brain Immunomodulation in HIV patients Improved vitality (increased testosterone levels in middle aged and young male adults) Ayurvedic protocols Gentle yoga stretches followed by 15-20 minutes of meditation Proper sleep Walk 7.5 km daily Limit/eliminate animal products, refined sugar and white flours Increase fiber intake and specific spices Reduce stress, anxiety and anger Results Reduced Hb A1c Decrease or reversal glucose intolerance Reduced fasting glucose Reduces cholesterol and LDL Decreased weight Improved peripheral insulin activity Increased peripheral blood flow Improvement in self-reported well-being and specific health https://unsplash.com/photos/V0xp-dTS3z0 Everydayhealth.com References Available upon request: [email protected]

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Page 1: Review of Evidence: Ayurvedic Practices for PT

Review of Evidence: Ayurvedic Practices for PT

Andrea Lopasso, DPT, Dr. Beth Phillips, PT, DPA, Woody Somvichai, DPT,

Shayan Safar, DPT, Bret Maddux, DPT, Nash Weinberg, DPT

Department of Physical Therapy

Introduction

Physical therapist (PT) spend more time with patients than most health care providers

allowing the time to educate patients about Complementary Integrative Therapies (CIT)

and provide nutritional guidance towards healthy, often more cost-effective, treatment

and prevention options with longer lasting results. As PTs in CA, we are legally allowed

to give nutritional advice and APTA supports the use of evidence based CIT practices.

Therefore this study delved into understanding the complexity of Ayurvedic Medicine

and herbal physiological effects with applications to physical therapy.

Ayurveda • Practiced > 10,000 years

• Meaning: Life knowledge - healthy way of being

• Primary aim: prevent disease

• Holistic: focus on physical, emotional & spiritual health

• Objective: • Guidance toward individual’s control of own health • Align lifestyle/nutritional habits to seasons/cycles of nature

• Emphasis: proper digestion, assimilation & elimination

• proper diet in accordance with • individual’s Dosha: physical/mental elements of Fire/”pita” – Wind/”vata” – Earth & Water/”Kapha” • and time of day & year

• Component of “YOGA” • Traditionally includes Ayurveda, meditation, asanas • In Western world reduced to physical exercise

Turmeric

Purpose

“The American Physical Therapy Association

supports the continued use of evidence-based

complementary and Integrative interventions in

physical therapy practice.” Therefore, the relevance

of this investigation of evidence is to bring

Awareness and knowledge of other forms of

therapies from which our patients can benefit.

PTs are well positioned to bridge the

east-west science gap.

Patients/health care consumers are seeking

alternatives that are:

• Cost efficient

• Safer for pain control to ↓ opioid epidemic

• Reduce excessive use of medications as people

become more aware of the negative side-effects

Ashwagandha

Diabetes and Ayurveda

Conclusion

Due to the holistic nature of Ayurveda, the empirical reductionist research model that tends to

isolate variables often cannot capture the magnitude of beneficial results found in the relationships

of the many Ayurvedic variables and their synergistic effects. However, research shows strong

evidence for herbal supplementation and its health benefits, many of which are directly applicable

to PT, and all of which could be beneficial to our patient’s overall health and wellbeing.

DPT curricula could be enriched by providing information on a variety of complimentary integrative

therapies including Ayurveda as part of wellness and prevention and for additional referral options

to benefit patients.

Scope of Practice: California Practice Act allows giving nutritional advice as long as Chapter 5

Article 3 is posted at the clinic. https://www.ptbc.ca.gov/forms/law_reference_guide.pdf

Strongest evidence:

• Modulates Anti-inflammatory Cytokines

• Decreases muscle pain post-exercise

• Improves muscle performance

• 1g as effective as pain medicine for arthritis

decreasing PVAS

Oregano

Strongest evidence:

• Antibacterial, antiviral and antimicrobial

dosage 2.0-2.5 µg/ml concentration

• Anti-inflammatory

decreases inflammatory cytokines

increases anti-inflammatory cytokines

dosage 35-70 µg/ml concentration

• Anti-nociception

extremely high doses needed

up to 100 mg/Kg body weight

Strongest evidence:

• Powerful adaptogen (↓ stress levels)

• Increases muscle strength and size

• Speeds up muscle recovery

• Prevents proliferative growth of tumors

• Promotes memory and mental capacity

• Protects from neurodegenerative disease

• Reduces biomarkers of clinical anxiety in the brain

• Immunomodulation in HIV patients

• Improved vitality (increased testosterone levels in

middle aged and young male adults)

Ayurvedic protocols

• Gentle yoga stretches followed by

15-20 minutes of meditation

• Proper sleep

• Walk 7.5 km daily

• Limit/eliminate animal products,

refined sugar and white flours

• Increase fiber intake and specific spices

• Reduce stress, anxiety and anger

Results

• Reduced Hb A1c

• Decrease or reversal glucose intolerance

• Reduced fasting glucose

• Reduces cholesterol and LDL

• Decreased weight

• Improved peripheral insulin activity

• Increased peripheral blood flow

• Improvement in self-reported well-being

and specific health

https://unsplash.com/photos/V0xp-dTS3z0

Everydayhealth.com

References – Available upon request: [email protected]

Page 2: Review of Evidence: Ayurvedic Practices for PT

REFERENCES

ASHWAGANDHA Singh, N., Bhalla, M., de Jager, P., & Gilca, M. (2011). An overview on ashwagandha: A Rasayana (Rejuvenator) of Ayurveda. African Journal of Traditional, Complementary and Alternative Medicines, 8(5S).

Sharma D, Roy V, Saraf A. An Update on Phytochemicals Analysis and Medicinal Prospects of Indian Herb Withania somnifera. Ambient Science. 2017;04(Sp1, & 02). doi:10.21276/ambi.2017.04.2.rv01.

Panossian A, Seo EJ, Efferth T. (2019) Effects of anti-inflammatory and adaptogenic effects of herbal extracts on isolated brain cells using systems biology. Phytomedicine. 2019 March 10: 152881.

Doi:10.1016/j.phymed.2019.152881

Maurya, S. P., Das, B. K., Singh, R., & Tyagi, S. (2019). Effect of Withania somnifer on CD38 expression on CD8 T lymphocytes among patients of HIV infection. Clinical Immunology.

doi:https://doi.org/10.1016/j.clim.2019.04.003

Ziegenfuss, T., Kedia, A., Sandrock, J., Raub, B., Kerksick, C., & Lopez, H. (2018). Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial. Nutrients, 10(11), 1807

Wankhede, S., Langade, D., Joshi, K., Sinha, S. R., & Bhattacharyya, S. (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. Journal of the International Society of Sports Nutrition, 12(1), 43.

Sharma D, Roy V, Saraf A. An Update on Phytochemicals Analysis and Medicinal Prospects of Indian Herb Withania somnifera. Ambient Science. 2017;04(Sp1, & 02). doi:10.21276/ambi.2017.04.2.rv01.

Panossian A, Seo EJ, Efferth T. (2019) Effects of anti-inflammatory and adaptogenic effects of herbal extracts on isolated brain cells using systems biology. Phytomedicine. 2019 March 10: 152881. Doi:10.1016/j.phymed.2019.152881

Maurya, S. P., Das, B. K., Singh, R., & Tyagi, S. (2019). Effect of Withania somnifer on CD38 expression on CD8 T lymphocytes among patients of HIV infection. Clinical Immunology. doi:https://doi.org/10.1016/j.clim.2019.04.003

Ziegenfuss, T., Kedia, A., Sandrock, J., Raub, B., Kerksick, C., & Lopez, H. (2018). Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial. Nutrients, 10(11), 1807

CARVACROL

Hammer KA, Carson CF, Riley TV. Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology. 1999;86(6):985-990. doi:10.1046/j.1365-2672.1999.00780.x.

Elgayyar M, Draughon F, Golden D, Mount J. Antimicrobial activity of essential oils from plants against selected pathogenic and saprophytic microorganisms. J Food Prot. 2001;64:1019Y1024.

Horne S. Oregano. The School of Modern Herbal Medicine. https://modernherbalmedicine.com/articles/oregano.html. Published June 19, 2013. Accessed March 24, 2020.

Guimarães AG, Oliveira GF, Melo MS, et al. Bioassay-guided Evaluation of Antioxidant and Antinociceptive Activities of Carvacrol. Basic & Clinical Pharmacology & Toxicology. 2010;107(6):949-957. doi:10.1111/j.1742-

7843.2010.00609.x.

Arigesavan K, Sudhandiran G. Carvacrol exhibits anti-oxidant and anti-inflammatory effects against 1, 2-dimethyl hydrazine plus dextran sodium sulfate induced inflammation associated carcinogenicity in the colon of Fischer

344 rats. Biochemical and Biophysical Research Communications. 2015;461(2):314-320. doi:10.1016/j.bbrc.2015.04.030.

Ocaña-Fuentes A, Arranz-Gutiérrez E, Señorans F, Reglero G. Supercritical fluid extraction of oregano (Origanum vulgare) essentials oils: Anti-inflammatory properties based on cytokine response on THP-1 macrophages. Food

and Chemical Toxicology. 2010;48(6):1568-1575. doi:10.1016/j.fct.2010.03.026.

Silva FV, Guimarães AG, Silva ER, et al. Anti-Inflammatory and Anti-Ulcer Activities of Carvacrol, a Monoterpene Present in the Essential Oil of Oregano. Journal of Medicinal Food. 2012;15(11):984-991.

doi:10.1089/jmf.2012.0102.

Han X, Parker TL. Anti-inflammatory, tissue remodeling, immunomodulatory, and anticancer activities of oregano ( Origanum vulgare ) essential oil in a human skin disease model. Biochimie Open. 2017;4:73-77.

doi:10.1016/j.biopen.2017.02.005.

TURMERIC

Daily JW, Yang M, Park S. Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Med Food.

2016;19(8):717–729. doi:10.1089/jmf.2016.3705

Fernández-Lázaro D, Mielgo-Ayuso J, Seco Calvo J, Córdova Martínez A, Caballero García A, Fernandez-Lazaro CI., Modulation of Exercise-Induced Muscle Damage, Inflammation, and Oxidative Markers by

Curcumin Supplementation in a Physically Active Population: A Systematic Review, Nutrients 2020, 12(2), 501

doi.org/10.3990/nu120501

Aggarwal, B.B., Yuan, W., Li, S. and Gupta, S.C. (2013), Curcumin‐free turmeric exhibits anti‐inflammatory and anticancer activities: Identification of novel components of turmeric. Mol. Nutr. Food Res., 57: 1529-

1542. doi:10.1002/mnfr.201200838

Mishra LC. Health Care and Disease Management. In: Mishra LC, ed. Scientific Basis for Ayurvedic Therapies. New York, NY: CRC Press; 2004: 15-29.

Tirtha SS. The Ayurvedic Encyclopedia. Bayville, NY: Ayurvedic Holistic Center Press; 1998: 3-35.

OREGANO

Tsigarida E, Skandamis P, Nychas G-J. Behaviour of Listeria monocytogenes and autochthonous flora on meat stored under aerobic, vacuum and modified atmosphere packaging conditions with or without the presence of

oregano essential oil at 5 oC. Journal of Applied Microbiology. 2000;89(6):901-909. doi:10.1046/j.1365-2672.2000.01170.x.

Paster N, Menasherov M, Ravid U, Juven B. Antifungal Activity of Oregano and Thyme Essential Oils Applied as Fumigants Against Fungi Attacking Stored Grain. Journal of Food Protection. 1995;58(1):81-85. doi:10.4315/0362-

028x-58.1.81.

Lambert R, Skandamis P, Coote P, Nychas G-J. A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol. Journal of Applied Microbiology. 2001;91(3):453-462.

doi:10.1046/j.1365-2672.2001.01428.x.

Melo FHC, Rios ERV, Rocha NFM, et al. Antinociceptive activity of carvacrol (5-isopropyl-2-methylphenol) in mice. Journal of Pharmacy and Pharmacology. 2012;64(12):1722-1729. doi:10.1111/j.2042-7158.2012.01552.x.

Singletary K. Oregano. Nutrition Today. 2010;45(3):129-138. doi:10.1097/nt.0b013e3181dec789.

Rostro-Alanis MDJ, Báez-González J, Torres-Alvarez C, Parra-Saldívar R, Rodriguez-Rodriguez J, Castillo S. Chemical Composition and Biological Activities of Oregano Essential Oil and Its Fractions Obtained by Vacuum

Distillation. Molecules. 2019;24(10):1904. doi:10.3390/molecules24101904.

Bukovská A, Cikoš Š, Juhás Š, Il’Ková G, Rehák P, Koppel J. Effects of a Combination of Thyme and Oregano Essential Oils on TNBS-Induced Colitis in Mice. Mediators of Inflammation. 2007;2007:1-9. doi:10.1155/2007/23296.

Dundar E, Olgun EG, Isiksoy S, Kurkcuoglu M, Baser KHC, Bal C. The effects of intra-rectal and intra-peritoneal application of Origanum onites L. essential oil on 2,4,6-trinitrobenzenesulfonic acid-induced colitis in the rat.

Experimental and Toxicologic Pathology. 2008;59(6):399-408. doi:10.1016/j.etp.2007.11.009.

DIABETES Elder, C., Aickin, M., Bauer, V., Cairns, J. and Vuckovic, N., 2006. Randomized Trial of a Whole-System Ayurvedic Protocol for Type 2 Diabetes. Alternative Therapies in Health and Medicine, 12(5).

Sharma, R. and Pk, P., 2014. Diet and Lifestyle Guidelines for Diabetes: Evidence Based Ayurvedic Perspective. Romanian Journal of Diabetes Nutrition and Metabolic Diseases, 21(4).