Resources for “South-South” Cooperation

Lymphatic Filariasis LaboratoryCentro de Ciências Biológicas

Universidade Federal de AlagoasMaceió, Alagoas State, Brazil

Prof. Gilberto Fontes Profa Eliana M. Mauricio da Rocha

Lymphatic Filariasis Elimination in the Americas5th Regional Program Review Group (RPRG) Meeting

(San José, Costa Rica, 27 October 2005)

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Lymphatic Filariasis

in Maceió

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Centro de Ciências BiológicasUniversidade Federal de Alagoas

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Centro de Ciências BiológicasUniversidade Federal de Alagoas

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Lymphatic Filariasis LaboratoryCentro de Ciências BiológicasUniversidade Federal de Alagoas

History

1990

Survey of Army SoldiersDra Gerusa Dreyer & Staff: 2 mf +

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Lymphatic Filariasis LaboratoryCentro de Ciências Biológicas

Universidade Federal de Alagoas

Epidemiological Study of LF in Maceió

- Survey of microfilariae carriers (Maceió): 72 mf + (Students)

- Distribution of LF endemic in Maceió: 3 city sectors

- Distribution of LF in Alagoas State: Maceió - Epidemiological study of LF in Maceió:

Human infection, entomological studies.

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Maceió

• Endemic infectious diseases • Small number of researchers • Few Health PG programs• Laboratory: Undergraduate students

from Medicine, Pharmacy, Biology, Nursing, Nutrition

Lymphatic Filariasis LaboratoryCentro de Ciências Biológicas

Universidade Federal de Alagoas

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Epidemiology

Entomology

Diagnostics

1990–2005: 525 undergraduate students, interns, fellows (CNPq / FAPEAL / UFAL / SMS)

Clinical Studies

Treatment

Health Education

Lymphatic Filariasis LaboratoryCentro de Ciências Biológicas

Universidade Federal de Alagoas

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Part of the Trainees TeamPart of the Trainees Team LF - MaceióLF - Maceió

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Part of the Trainees TeamPart of the Trainees Team LF - MaceióLF - Maceió

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Lymphatic Filariasis LaboratoryCentro de Ciências BiológicasUniversidade Federal de Alagoas

Field Activities Survey of the general population Health information Nighttime blood collection

• Finger prick• Venous blood collection

Treatment and patient follow-up Child Survey - ICT Card Test

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Previous registryThick blood smear

Fieldwork

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Microscopy examination

Database EPI-info

Membrane filtration

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Endemic area

Canal (Reginaldo)

Lymphatic Filariasis LaboratoryCentro de Ciências Biológicas

Universidade Federal de Alagoas

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Surveys: Maceió, Alagoas

1999 2,821 examined 21 microfilaremics (0.74%)

2000 12,669 examined 69 microfilaremics (0.54%)

2001 13,544 examined 66 microfilaremics (0.49%)

2002 24,159 examined 23 microfilaremics (0.10%)

2003 7,450 examined 6 microfilaremics (0.08%)

2004

2005

6,715 examined

7,553 examined -

4 microfilaremics

0 microfilaremic

(0.06%)

(0.00%)

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Collaborations

- Fundação Nacional de Saúde (FUNASA)

- Ministério da Saúde do Brasil / Secretaria da Vigilância em Saúde (MS/SVS)

- Secretaria Municipal de Saúde de Maceió . LF Elimination Program

- Centro de Pesquisas René Rachou, FioCruz . Standardization of Polymerase Chain Reaction

(PCR)

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Collaborations- Secretaria Estadual de Saúde de Belém . Thick Blood Smear Evaluation ( 2001–2003) . Children’s ICT card . Xenomonitoring for PCR

- Secretaria Estadual de Saúde da Bahia . Xenomonitoring for PCR (2005)

- Centro de Pesquisas Aggeu Magalhães, FioCruz

. Surveys and follow-up . Immunological studies for antigenemia

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Collaborations

- OPAS/OMS (PAHO/WHO-Brazil)

- ICT card surveys

- An integrated, community based approach in the control of soil transmitted worms

- COMBI Project (Communication of Behavioural Impact) in LF area

- IPK Cuba (Luis Fonte): PCR Entamoeba

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Collaborations

- PCR Leishmania and PCR Entamoeba- PhD thesis UFPE

- Experimental antimalarial chemotherapy- Natural products

Postgraduate Health Program at UFAL (September 2005)

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