Resource BinderResource BinderSBI 4USBI 4U

E: HomeostasisE: Homeostasis

Alessia, Laura, Paul, & Sheena

AGENDAAGENDA

Essential Question Hook Unit Plan Historical Topic: History of Homeostatic Systems Dry Lab Wet Lab STSE Culminating Activity Recent Research: Article Analysis and Forum

Essential QuestionEssential Question

“What is the effect on homeostasis of the introduction of performance-enhancing drugs?”

HookHookMouse Party

– Introduces homeostasis of neural systems– Important hook for STSE Activity– http://learn.genetics.utah.edu/content/addiction/drugs/mouse.html

– Not meant to endorse drug use!

Dry LabDry Lab

The Urinary System Exposed!– the urinary system– feedback mechanisms– water balance– effects of alcohol

links to the STSE activity!

Image from http://www.cic-caracas.org/departments/science/Topic12.php

Dry lab – Part ADry lab – Part A

NaCl

NaCl, urea, H2O

H2OH2O, HCO3-, NaCl, K+, nutrients

H+, NH3

H+, K+ NaCl, H2O, HCO3-

Dry lab – Part BDry lab – Part B Comparing solutes in plasma, nephron and urine Sample question: What happened to the levels of urea

and ammonia after filtration? Explain why this occurs.

Table 1. Concentrations of solutes in the Bowman's capsule, glomerulus, loop of Henle and collecting duct in g/100 mL (from Nelson 2003)

Solute Bowman’s capsule Glomerulus Loop of Henle Collecting duct

protein 0 0.8 0 0

urea 0.05 0.05 1.5 2

glucose 0.1 no data 0 0

chloride (Cl-) 0.37 no data no data 0.6

ammonia (NH3)0.0001 0.0001 0.0001 0.04

substance X 0 9.15 0 0

Dry lab – Part CDry lab – Part CAntidiuretic hormone (ADH)Negative feedback systemEffect of alcohol on ADH and urine

formation

Wet LabWet Lab

STSE Culminating ActivitySTSE Culminating Activity

Article Analysis and ForumArticle Analysis and Forum