reserach final2012n.pptx

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    Students Scientific Research Society (SSRS)

    studies who are interested

    1-in doing research& advancement2- the students have the opportunity to get a deeper

    insight into the principles and methods of research,

    3 -to participate actively in research activities and torealize their own ideas and present results at the

    students and other meetings,

    4- satisfying thus their needs and interests that are not

    presented in the course of regular studies. knowledge

    in the areas of their own interest.

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    EXPERTISE OF THAT WELL BE AQUIRED BY THE

    (SSRS) GROUP

    Breeding and treatment of laboratory animals includingvarious surgical techniques, as well as different ways of

    administering/applying drugs and biologically active

    substances.Cell cultures and tissues: preparation and culturing of

    different types of cells

    How to use top quality electron microscopy instruments.,both scanning and transmission electron microscope as

    well as atomic force microscope AFM

    How to use different Scientific Methodology

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    INTRODUCTION TO RESEARCH

    (SCIENTIFIC INQUIRY)

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    WHAT IS RESEARCH?

    A voyage of discovery; A journey; An

    attitude ; An experience; A careful

    critical enquiry in seeking facts for

    principles.

    A It requires a clear goal

    It follows a specific course of action

    It is realistic in its assumptions

    It is performed by qualified personal

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    WHAT IS RESEARCH?

    research is an unusually stubborn

    (insistent) and persisting effort to

    think straight which involves thegathering and the intelligent use of

    relevant data

    H. M. Hamlin, What is Research? American

    Vocational Journal, September 1966.

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    A pursuit for an answer driven by a specific

    question or idea

    It requires a clear goal

    It follows a specific course of action It is realistic in its assumptions

    It is performed by qualified personal

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    Why scientific research?

    Advances of knowledge; fulfill curiosity

    Advances of civilization; improve life quality

    Financial reward?

    Fame?

    Hard work with little reward sometime;

    scientific research is not for everyone.

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    Research is not

    Just information gathering

    Rearranging of facts Good Research is based on several

    pillars:

    Vision

    Strategy

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    The very first few steps

    What is (are) the hypothesis or

    hypotheses to be proved or disproved?

    Why is this research? What are the objectives?

    How to do it?

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    RESEARCH

    The priority of Research

    should be directed to solvingproblems of society rather

    than publishing.

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    SELECTING A RESEARCH PROBLEM

    Selecting a research problem and defining it is

    perhaps the most difficult part of doing scientific

    research. For some of us, they come easy. For

    others, not so easy.

    Where do research problems come from?

    Personal experience/observation of the

    world.? There are no rules which limit what is a valid

    topic for research.

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    THERE ARE MANY SORTS OF QUESTIONS THAT

    RESEARCH CAN ADDRESS.

    l- A etiology: what caused this illness?

    2- Diagnosis: what does this test result mean in this patient?

    3-Prognosis: what is likely to happen to this patient?

    4-Harm: is having been exposed to this substance likely to do harm,

    and, if so, what?

    5- Effectiveness: is this treatment likely to help patients with this

    illness?

    6- Qualitative: what are the outcomes that are most important to

    patients with this condition?

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    THE IDEA

    One can come up with good ideas aboutclinical research based on gaps in existing

    knowledge Has question been asked before?

    If not, why?

    If so, how does my question or design add tothe existing literature?

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    THE SCIENTIFIC METHOD

    Hypothesis: groundwork,

    foundation; an unproven

    theory.

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    FORMULATING HYPOTHESES

    An hypothesis is an explicit (clear) statement bythe researcher of how phenomena of interest

    are related to one another.

    Characteristics of a good hypothesis It is an empirical (realistic )statement.

    It is reasonable.

    It is specific. It is testable.

    EARLY STEPS IN CLINICAL

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    EARLY STEPS IN CLINICAL

    RESEARCH

    The idea What topic interests you

    The hypothes is the possible answer you will try to

    prove or disprove.

    hypothesis is an educated guess about how things

    work. Most of the time a hypothesis is written like this:

    "If _____[I do this] _____, then _____[this]_____ will

    happen."

    independent variable++++===dependent variable

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    If I open the faucet [faucet opening size is the independentvariable], then it will increase the flow of water [flow of water is

    the dependent variable].

    "Raising the temperature of a cup of water [temperature is the

    independent variable] will increase the amount of sugar thatdissolves [the amount of sugar is the dependent variable]."

    "If a plant receives fertilizer [having fertilizer is the independent

    variable], then it will grow to be bigger than a plant that does not

    receive fertilizer [plant size is the dependent variable]."

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    .

    If plant leafcolor change is related to

    temperature , then exposing plants to lowtemperatures will result in changes in leaf color.

    Ultra violet light may cause skin cancer. If skin canceris related to ultraviolet light , then

    people with a high exposure to uv light will have

    a higher frequency of skin cancer.

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    FINDING THE RIGHT TARGET IS NOT EASY

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    FINDING THE RIGHT TARGET IS NOT EASYPARKINSONS DISEASE EXAMPLE:

    Parkinson's disease:

    a disease which causes

    deterioration of the

    central nervous system

    over a period of time.

    This disease often

    impairs the patients

    movement, speech, and

    other functions.

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    Ways of Knowing

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    DISSECTING THE DIMENSIONS OF RESEARCH :

    topic:

    technology: develop new vs use existing methods

    scope: study a single case vs a sample

    methodology: qualitative vs quantitative

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    Quantitative (measurable) Qualitative

    TWO APPROACHES TO RESEARCH

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    Quantitative

    Test theory

    Establish facts

    Show relationships

    Statistically describe

    Qualitative

    Understand theory

    Develop understanding

    Describe multiple realities

    GOALS

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    Quantitative

    Large

    Representative

    Random Selection

    Control Groups

    Qualitative

    Small

    Nonrepresentative

    Purposeful

    SAMPLE

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    Quantitative

    Experiments

    Qualitative

    Observation

    METHODS

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    WHICH APPROACH IS BEST?

    The problem you are studying determines which

    approach to take.

    One is not better than the other.

    However, some researchers tend to look down their

    nose at the qualitative researcher!

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    WHICH WOULD YOU SELECT?

    .

    Decide whether to approach this problem quantitatively orqualitatively

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    MIXED METHODS

    Some researchers used both

    qualitative and quantitative methods in

    a single study. This is known as amixed method approach.

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    THE END

    Dont be afraid of

    research. It can actually

    be fun!

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    Thank you