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Rese
arch
Nee
ds fo
r Hig
h-th
roug
hput
As
sess
men
t of E
nviro
nmen
tal C
onta
min
ants
, an
d Su
stai
nabl
e M
olec
ular
Des
ign
and
Alte
rnat
ives
Anal
ysis
of C
hem
ical P
rodu
cts
Brya
n W
. Bro
oks
Bayl
or U
nive
rsity
Uni
ted
Nat
ions
Glo
bal G
oals
ww
w.gl
obal
goal
s.or
g
ww
w.gl
obal
goal
s.or
g
12.4
“By
2020
, ach
ieve
the
envi
ronm
enta
lly
soun
d m
anag
emen
t of c
hem
ical
s an
d al
l was
tes
thro
ugho
ut th
eir l
ife c
ycle
, in
acc
orda
nce
with
agr
eed
inte
rnat
iona
l fra
mew
orks
, and
sig
nific
antly
redu
ce
thei
r rel
ease
to a
ir, w
ater
and
soi
l in
orde
r to
min
imiz
e th
eir a
dver
se
impa
cts
on h
uman
hea
lth a
nd th
e en
viro
nmen
t”
12.5
“By
2030
, sub
stan
tially
redu
ce w
aste
ge
nera
tion
thro
ugh
prev
entio
n,
redu
ctio
n, re
cycl
ing
and
reus
e”
Why
now
?-O
ther
dis
cipl
ines
(e.g
., co
nser
vatio
n bi
olog
y,
agric
ultu
re) h
ave
bene
fited
from
hor
izon
sca
nnin
g ex
erci
ses
-Env
ironm
enta
l sci
ence
has
resp
onde
d to
man
y is
sues
, ye
t has
not
und
erta
ken
such
a p
rosp
ectiv
e ac
tivity
-Ans
wer
s to
env
ironm
enta
l que
stio
ns a
re n
eede
d…
But
whi
ch o
nes?
WHY
GLO
BAL
HORI
ZON
SCAN
NING
?
Inte
rest
from
fund
ers
and
gove
rnm
ents
in re
sults
from
big
que
stio
nex
erci
ses,
but
als
o in
the
proc
ess…
•
Ofte
n go
vern
men
t em
ploy
ees
prov
ide
inpu
t in
ques
tion
deve
lopm
ent p
roce
ss –
polic
y vo
ice
to h
elp
dire
ct a
nd s
hape
rese
arch
age
nda
Thes
e ex
erci
ses
can
have
mul
tiple
impa
cts
•U
K M
arin
e Sc
ienc
e St
rate
gy &
Agr
icul
tura
l po
licy
–ve
rbat
im u
se o
f Sut
herla
nd•
Thes
e ar
e in
here
ntly
bot
tom
-up
exer
cise
sR
udd
et a
l. 20
14. I
EA
M
KEY LESSON
S
Inte
rest
from
fund
ers
and
gove
rnm
ents
in re
sults
from
big
que
stio
nex
erci
ses,
but
als
o in
the
proc
ess…
•
Ofte
n go
vern
men
t em
ploy
ees
prov
ide
inpu
t in
ques
tion
deve
lopm
ent p
roce
ss –
polic
y vo
ice
to h
elp
dire
ct a
nd s
hape
rese
arch
age
nda
Thes
e ex
erci
ses
can
have
mul
tiple
impa
cts
•U
K M
arin
e Sc
ienc
e St
rate
gy &
Agr
icul
tura
l po
licy
–ve
rbat
im u
se o
f Sut
herla
nd•
Thes
e ar
e in
here
ntly
bot
tom
-up
exer
cise
s –
pote
ntia
lly m
ore
legi
timac
yR
udd
et a
l. 20
14. I
EA
M
KEY LESSON
S
-Nu
mer
ous
glob
al c
halle
nges
and
opp
ortu
nitie
s ex
ist to
ac
hiev
e su
stai
nabl
e en
viro
nmen
tal
qual
ity a
nd e
cosy
stem
inte
grity
-En
viro
nmen
tal s
cienc
e ha
s re
spon
ded
to m
any
issue
s, b
ut
has
not u
nder
take
n a
pros
pect
ive
activ
ity to
iden
tify
stra
tegi
c gl
obal
rese
arch
nee
ds
Broo
ks e
t al 2
013
WHY
GLO
BAL
HORI
ZON
SCAN
NING
?
-Th
e Gl
obal
Hor
izon
Scan
ning
Pro
ject
ai
ms
to id
entif
y im
porta
nt
envi
ronm
enta
l qua
lity
rese
arch
ne
eds
-Re
sear
ch q
uest
ions
iden
tifie
d in
th
is pr
ojec
t, if
answ
ered
, wou
ld
mar
kedl
y ad
vanc
e m
ore
sust
aina
ble
envi
ronm
enta
l qua
lity
over
the
next
dec
ade
Broo
ks e
t al 2
013
WHY
GLO
BAL
HORI
ZON
SCAN
NING
?
Afric
aLa
ngeb
aan,
Sou
th A
frica
Asia
Sing
apor
e, S
inga
pore
Aust
ralas
iaNe
lson,
New
Zea
land
Euro
peBa
rcel
ona,
Spa
inLa
tin A
mer
icaBu
enos
Aire
s, A
rgen
tina
North
Am
erica
Salt
Lake
City
, USA
Each
wor
ksho
p tri
chai
red
by e
xper
ts fr
om a
cade
mia
, go
vern
men
t and
bus
ines
s
THE
GLOB
AL W
ORKS
HOPS
Coup
led
Hum
an a
nd E
colo
gica
l Fra
mew
orks
Inte
grat
ive N
eeds
for P
ublic
Hea
lth a
nd th
e En
viron
men
t
Whi
ch c
hem
icals,
nat
ural
or s
ynth
etic,
par
ent
com
poun
ds o
r met
abol
ites,
are
the
mai
n dr
iver
s of
m
ixtur
e to
xicity
in h
uman
s an
d th
e en
viro
nmen
t?
Inhe
rent
Con
nect
ions
am
ong
Hum
an H
ealth
, Eco
syst
ems
and
Envi
ronm
enta
l Qua
lity
Urba
niza
tion
and
Conc
entra
tion
of C
hem
ical U
seUn
ders
tand
and
Man
age
Cum
ulat
ive S
tress
ors,
Mixt
ures
Whe
n an
d un
der w
hat c
ircum
stan
ces
do
inte
ract
ions
(e.g
., ec
olog
ical,
chem
ical,
phys
iolo
gica
l) oc
cur t
hat
are
not c
aptu
red
by c
urre
ntly
ac
cept
ed m
ixtur
e to
xicity
mod
els?
Glob
al M
egat
rend
s an
d En
viro
nmen
tal Q
ualit
y
S.R
. Bur
ket
ww
w.gl
obal
goal
s.or
g
11.6
“B
y 20
30, r
educ
e th
e ad
vers
e pe
r cap
ita
envi
ronm
enta
l im
pact
of c
ities
, inc
ludi
ng
by p
ayin
g sp
ecia
l atte
ntio
n to
air
qual
ity
and
mun
icip
al a
nd o
ther
was
te
man
agem
ent”
Adva
ncin
g hi
stor
ically
des
crip
tive
effo
rtsCo
mpa
rativ
e To
xicol
ogy,
Mol
ecul
ar In
itiat
ion
Even
ts,
Ecol
ogica
l Gen
omics
, Beh
avio
r, Hi
gh T
hrou
ghpu
t Tes
ting
How
do
we
crea
te h
igh-
thro
ughp
ut s
trate
gies
for
pred
ictin
g hu
man
and
eco
logi
cally
rele
vant
effe
cts
and
proc
esse
s (e
.g.,
beha
vior
, mul
tigen
erat
iona
l, de
laye
d an
d in
dire
ct e
ffect
s)?
Ecot
oxico
logy
and
Env
ironm
enta
l To
xicol
ogy
-Mat
ured
to
Mec
hani
stic
Scie
nces
Curre
nt E
nviro
nmen
tal A
sses
smen
t Con
cern
sNe
w m
odels
, ana
lytica
l too
ls ne
eded
to u
nder
stan
ding
fate
an
d ex
posu
re o
f hist
orica
l and
em
ergi
ng c
onta
min
ants
How
can
dat
a on
the
occu
rrenc
e of
con
tam
inan
ts o
f em
ergi
ng c
once
rn in
the
envi
ronm
ent a
nd q
ualit
y of
ec
osys
tem
s ex
pose
d to
thes
e co
ntam
inan
ts b
e us
ed
to d
eter
min
e w
heth
er c
urre
nt re
gula
tory
risk
as
sess
men
t sch
emes
are
effe
ctiv
e?
Envi
ronm
enta
l Ass
essm
ent a
nd
Effe
ctiv
e M
anag
emen
t
Adva
ncin
g su
stai
nabi
lity
thro
ugh
desig
nSu
bstit
utio
ns, a
ltern
ative
s and
the
ratio
nal d
esig
n of
less
ha
zard
ous c
hem
icals
How
can
we
bette
r man
age,
us
e an
d sh
are
data
gen
erat
ed
from
exis
ting
test
ing
stra
tegi
es
in o
rder
to d
evel
op m
ore
sust
aina
ble
and
safe
r pro
duct
s?
Gree
n Ch
emist
ry &
Eng
inee
ring
and
Envi
ronm
enta
l Qua
lity
Coi
shet
al 2
016.
AC
S S
usC
hem
Eng
Cor
rale
s et
al 2
017.
Che
mR
es T
oxic
ol
Adva
ncin
g su
stai
nabi
lity
thro
ugh
desig
nSu
bstit
utio
ns, a
ltern
ative
s and
the
ratio
nal d
esig
n of
less
ha
zard
ous c
hem
icals
How
can
we
impl
emen
t co
mpa
rativ
e ris
k as
sess
men
t, lif
e cy
cle a
naly
sis, a
nd ri
sk
bene
fit a
naly
sis in
ord
er to
id
entif
y an
d de
sign
mor
e su
stai
nabl
e al
tern
ativ
es?
Gree
n Ch
emist
ry &
Eng
inee
ring
and
Envi
ronm
enta
l Qua
lity
THA
NK
YO
U!