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Removing worn-out cells makes mice live longer and prosperAntiaging treatment shows promise for lengthening life spanBY TINA HESMAN SAEY 1:00PM, FEBRUARY 3, 201

!illing worn"o#t $ells helps mi%%le"age% mi$e li&e longer, healthierli&es, a new st#%' s#ggests(Remo&ing those worn"o#t or )senes$ent* $ells in$rease% the me%ianlife span of mi$e from 2+ to 2 per$ent o&er that of ro%ents in whi$hsenes$ent $ells -#ilt #p normall' with age, Ma'o .lini$ resear$hersreport online Fe-r#ar' 3 in Nature ( .learing senes$ent $ells alsoimpro&e% heart an% /i%ne' f#n$tion, the resear$hers fo#n%(

f the res#lts hol% #p in people, the' $o#l% lea% to an entirel' new wa'to treat aging, sa's gerontolog' an% $an$er resear$her ormanharpless at the Uni&ersit' of orth .arolina $hool of Me%i$ine in

.hapel ill( Most prospe$ti&e antiaging treatments wo#l% re4#irepeople to ta/e a %r#g for %e$a%es(

Random changes in ehavior speed acteria evolution.omp#ter mo%eling of how mi$ro-es m#tate $o#l% pro&i%e $l#es to -attling anti-ioti$ resistan$eBY !HRIS SAM"RAY

:00AM, FEBRUARY 1, 201Ran%om $hanges in mi$ro-es5 -eha&ior $an spee% #p e&ol#tion, anew st#%' shows(

6hese shifts 7 $alle% phenot'pe swit$hes 7 $an promote geneti$m#tations that help mi$ro-es -etter s#r&i&e their en&ironment,resear$hers report online 8an#ar' 19 at BioR i&(org( Un%erstan%inghow the mi$ro-es e&ol&e is )parti$#larl' important for anti-ioti$resistan$e,* sa's st#%' $oa#thor Bartlomie;

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A %e$line in o$ean mi ing %#e to warming s#rfa$e waters is to -lamefor that ph'toplan/ton pl#mmet, resear$hers propose online 8an#ar'19 in Geophysical Research Letters ( 6he mi ing of the o$ean5s la'ersferries ph'toplan/ton n#trients from the o$ean5s %ar/ %epths #p intothe s#nlit la'ers that the mini plants inha-it(

Immune s&stem gene leads to schi(ophrenia clueE $essi&e s'napse pr#ning lin/e% to protein &ariant

BY )A'RA SAN*ERS 12:G PM, 8A UARY 29, 201

From the tangle% we- of s$hi?ophrenia -iolog', s$ientists ha&ep#lle% o#t one tantali?ing threa%( Hariants of a protein thathelps snip $onne$tions -etween ner&e $ells in the -rain ma'$ontri-#te to the %isor%er, s$ientists report 8an#ar' 2 in Nature () t5s not the answer, -#t it5s an answer,* sa's ps'$hiatrist an%ne#ros$ientist enr' asrallah of aint o#is Uni&ersit' $hool ofMe%i$ine( 6he @n%ings gi&e s$ientists a $l#e that ma' help #nra&elmore insights into how s$hi?ophrenia ta/es hol% of the -rain, hesa's(

6he resear$h was spar/e% -' geneti$ st#%ies that i%enti@e% amammoth stret$h of I A on $hromosome as parti$#larl's#spi$io#s( .alle% the ma;or histo$ompati-ili t' $omple , or M ., this

I A $h#n/ $arries information #se% -' the imm#ne s'stem to help i%entif' in&a%ers(

Tracking health is no sweat with new device

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Ji/a &ir#s is ;#st the latest mos4#ito"-orne %isease to rea$h the Ameri$as( Ieng#e fe&er $a#ses se&ere hea%a$hes, ;oint an% m#s$le pain an% other s'mptoms( t $an -e %ea%l'( )Ieng#e hit with a &engean$e in the 590s,* Fa#$i notes(

e is %ire$tor of the ational nstit#te of Allerg' an% nfe$tio#s Iiseases in Bethes%a, M%(

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6he small, -l#ish +yprino(on (ia#olis @sh inha-its Ie&ils ole, a$ollapse% $a&ern @lle% with water in the Mo;a&e Iesert( 6o e plainhow @sh got into s#$h hostile terrain, -iologists ha&e spe$#late%that +! (ia#olis an% some relate% lo$al p#p@shes in the area%es$en% from resi%ents of an$ient -o%ies of water that%isappeare% from the region more than 10,000 'ears ago( As thosewaters re$e%e%, @shes too/ ref#ge where the' $o#l%, the i%eagoes( B' now, %es$en%ants ha&e a%apte% to o%% remnant ha-itatsof wetter %a's(

6hat int#iti&el' appealing stor', howe&er, %oes not @t with hintsfrom new geneti$ e&i%en$e, sa's .hristopher Martin of the

Uni&ersit' of orth .arolina at .hapel ill( 6he Ie&ils ole p#p@shappears to ha&e re$entl' share% genes with %esert p#p@shes that li&e in springs or other water' pla$es 7 perhaps-etween 10G an% >G0 'ears ago( o the Ie&ils ole p#p@sh ma' not ha&e -een reall' isolate% as a spe$ies as long ason$e tho#ght( An% it ma' not e&en ha&e mo&e% in to its water' hole in the %esert re$entl', Martin an% $olleag#es sa'

8an#ar' 2 in ,rocee(in's o) the Royal Society -!

http://rspb.royalsocietypublishing.org/lookup/doi/10.1098/rspb.2015.2334http://rspb.royalsocietypublishing.org/lookup/doi/10.1098/rspb.2015.2334