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Remaining Vital in aPandemic Prone World
Robert Breakey, M.D.June 14, 2020
Disclosure:
I have no actual or potential conflict of interest in relation to this
program/presentation
The Spanish Flu: 1918 = 500M infected, 50+M died…
Notable Epidemics and Pandemics in History:
430 BC Plague of Athens
541 Plague of Justinian
1346 The Black Death
1918 Spanish Flu (H1N1)
Notable Epidemics and Pandemics in History:
430 BC Plague of Athens
541 Plague of Justinian 971 years
1346 The Black Death 805 years
1918 Spanish Flu (H1N1) 572 years
1957 Asian Flu (H2N2)
1968 Hong Kong flu
1981 AIDS
2002 SARS
Notable Epidemics and Pandemics in History:
1957 Asian Flu (H2N2) 39 years
1968 Hong Kong flu 11 years
1981 AIDS 13 years
2002 SARS 21 years
Notable Epidemics and Pandemics in History:
Notable Epidemics and Pandemics in History:
2004 Avian Flu
2009 Swine flu (H1N1)
2011 MERS
2014 Ebola
2015 Zika
2020 COVID-19
Notable Epidemics and Pandemics in History:
2004 Avian Flu 2 years
2009 Swine flu (H1N1) 5 years
2011 MERS 2 years
2014 Ebola 3 years
2015 Zika 1 year
2020 COVID-19 5 years
So WHY are we now in a “Pandemic-Prone World”?
By all accounts, things should be Better as we have:
Sanitation services
Water chlorination
Sewage treatment plants
Understanding of the “Germ Theory”
Vaccines
Antibiotics
Modern medical care
Public Health Departments
So WHY are we now in a “Pandemic-Prone World”?
So WHY are we now in a “Pandemic-Prone World”?
Instead, things are worse as we have:
So WHY are we now in a “Pandemic-Prone World”?
Instead, things are worse as we have:
Jets
So WHY are we now in a “Pandemic-Prone World”?
Instead, things are worse as we have:
Jets
Wild Animal Wet Markets
and Factory Farms
So WHY are we now in a “Pandemic-Prone World”?
Instead, things are worse as we have:
Jets
Wild Animal Wet Markets
and Factory Farms
Chronic Disease Epidemics
So WHY are we now in a “Pandemic-Prone World”?
Instead, things are worse as we have:
Jets
So WHY are we now in a “Pandemic-Prone World”?
Instead, things are worse as we have:
Wild Animal Wet Markets
and Overcrowded Factory Farms
“Human Diseases” Originate in Animals
Tuberculosis - Goats
Measles, Smallpox – Cows
Whooping cough – Pigs
Typhoid Fever – Chickens
Ducks – Influenza
AIDS - Chimpanzees
“How Not to Die”: M. Greger, M.D., p. 79
Corona Virus Origin…
Corona Virus Origin…
Bats
.
.
4 of 7 Cause the Common Cold
Corona Virus Origin…
Bats
Civet Cats
SARS - 2002 .
.
HUMANS
Corona Virus Origin…
Bats
Civet Cats
SARS - 2002MERS - 2012
.
.
HUMANS
Camels
Corona Virus Origin…
Bats
Civet Cats
SARS - 2002MERS - 2012
.
.
COVID -19
HUMANS
PangolinCamels
Corona Virus Origin…
Corona Virus Origin…
Corona Virus Origin…
Our “Corona Virus Equivalent”breeding ground:
Our “Corona Virus Equivalent”breeding ground:
2009 Swine Flu 1.6M Confirmed cases700M to 1.4B likely infectedWith ~300,000 deaths
Our “Corona Virus Equivalent”breeding ground:
Mad Cow diseaseFrom Cannibalistic Feeding Practices
Our “Corona Virus Equivalent”breeding ground:
Avian Influenza H5N1• Rare but deadly Strains• 50% Fatal• 50 Billion+ Chicken
“incubators”
Our “Corona Virus Equivalent”breeding ground:
Bovine Leukemia Virus
Lab Invest. 1994 Sept;71(3):359-65
BLV and Breast Cancer
PLoS One, 2015, Sept 2;10(9) eo34304
National FDA Retail MeatSurvey 2011…
National FDA Retail MeatSurvey 2011…
“90% of retail chickenshowed evidence of contamination with fecal matter…
How Not to Die; Michael Greger, MD, 2015 p. 93
Animal Foods and Infections:Contaminated with Animal Fecal Matter:• Chicken = 90%•Ground Turkey = 91%•Ground Beef = 88%• Pork Chops = 80%
USDA. NARMS 2011 retail meat annual report
CDC 2015 report
Animal Foods and Infections:Contaminated with Animal Fecal Matter:• Chicken = 90%•Ground Turkey = 91%•Ground Beef = 88%• Pork Chops = 80%
USDA. NARMS 2011 retail meat annual report
48+ Million Sickened AnnuallyCDC 2015 report
Animal Foods and Infections:And to make things worse…Many of these bacteria are resistant to antibiotics since 80% of allantibiotics in America are fed to farmanimals…
In the Event of a Nuclear Attack:Duck And Cover!
The largest and oldest association of public health professionals in the world, the American Public Health Association, has called for a moratorium on factory farming for nearly two decades. Its journal published an editorial entitled “The Chickens Come Home to Roost” that went beyond calling for a deintensification of the pork and poultry industries:
Michael Greger: nutritionfacts.org
“It is curious, therefore, given the pandemic threat, that changing the way humans treat animals, most basically ceasing to eat them, or at the very least, radically limiting the quantity of them that are eaten—is largely off the radar as a significant preventive measure. …
Michael Greger: nutritionfacts.org
… Such a change, if sufficiently adopted or imposed, could still reduce the chances of the much-feared influenza epidemic. It would be even more likely to prevent unknown future diseases that, in the absence of this change, may result from farming animals intensively and killing them for food. Yet humanity doesn’t even consider this option.”
Michael Greger: nutritionfacts.org
Example for Coronary Artery Disease:
Primary - Healthy DietSecondary – Low dose Aspirin after MITertiary – Cardiac Rehab
And for Pandemics:
Primary - Factory Farms / Wet MarketsSecondary – Chronic DiseaseTertiary – Jets
First Line of Defense:Prevent Exposure- CDC Guidelines:
• Wash your hands often• Avoid touching your eyes, nose, and mouth• Avoid close contact• Cover your mouth and nose with a cloth
face cover when around others• Cover coughs and sneezes• Clean and disinfect
2nd Line of Defense:A Strong Immune System
Basic Logic:
If A and B Then CCOVID Exposure High Risk of Severe
Chronic Disease
Basic Logic:
If A and B Then CCOVID Exposure High Risk of Severe
Chronic Disease
Basic Logic:
If A and B Then CCOVID Exposure High Risk of Severe
Chronic Disease
Death Certificates List“Co-Morbidities”
3rd Line of Defense:Avoid Obesity, Diabetes, CAD, HTN:
Just like to:Avoid Lung Cancer and COPD:
Leading cause of death and disability in the US:
The Standard American Diet1993:1. Tobacco2. Diet and Activity 3. Alcohol
JAMA. 1993;270:2207-12
2018:1.Dietary Risk2.Tobacco3.Chronic Diseases
JAMA. 2018;319(14):1444-1472
ANIMAL PLANT P
RO
CES
SED
UN
PR
OC
ESSE
D
These processedFAT / SALT / SUGAR
“foods” designed by “food chemists” to addict us are not really
food at all…
ANIMAL PLANT P
RO
CES
SED
UN
PR
OC
ESSE
D
What is “Food”?
Functional Nutrient ResearchTens of Thousands of Studies Document
that Optimal Diet Can…
Improve Performance
Heal Injuries
Increase Health
Increase Vitality
Improve Well-Being
Increase Longevity
What makes a food “Health Supporting”?
DesirableCharacteristics:
Plant Foods Animal Foods
Anti Oxidant Rich
High Fiber
Alkaline
Cholesterol Free
Anti Inflammatory
Phytonutrient Rich
Balanced /HealthyMacronutrients
Michael Greger, MD www.nutritionfacts.org
Michael Greger, MD www.nutritionfacts.org
The process of extracting
Energy from food is “messy”…
Free Radicals are formed…
Cellular Damage
Rapid Cell Aging
Organ Dysfunction
Proteins Denatured
Immune Response
Inflammation
DNA Damage
Mutations
Cancer
Endothelial Damage
Atheroma
CAD/Stroke
Free Radicals are highly reactive
Antioxidant Examples:
• Vitamin E
• Vitamin C
• Beta-carotene
• Lutein
• Lycopene
• Selenium
• Vitamin A
• 1000s of others
DesirableCharacteristics:
Plant Foods Animal Foods
Anti Oxidant Rich
High Fiber
Alkaline
Cholesterol Free
Anti Inflammatory
Phytonutrient Rich
Balanced /HealthyMacronutrients
Feed them Well and they Will: Support Immune function Support Hormone Balance Manage Toxins Nourish Your Colon Lower Inflammation Produce Nutrients Signal Satiety Aid Nutrient Absorption
Starve them and they Will: Inflame Colon Produce Toxins Increase Estrogens Increase Serum Cholesterol Induce Inflammation Create “Leaky Gut” Increase Autoimmune Disease Risk
And what do they eat?
How much fiber do we need?
Average American intake = 15 gm
Dietary Guidelines = 30 gm
Minimum Goal = 60 gm
Optimal = 100+ gm/ day
020406080
100120140160
Fiber (gm) / 2000 calories
Fiber (gm) / 2000 calories
Fiber (gm) / 2000 calories
Egg = 0
Cheese = 0
Olive Oil = 0
Chicken = 0
White Bread = 17
Walnut = 20
Minimum Goal = >30
Barley = 62
Blueberry = 84
Pinto Beans = 144
Broccoli = 152
Kale = 227
Starvation
Nourishment
Dietary Fiber and Risk of Disease David Donohue, MD
DesirableCharacteristics:
Plant Foods Animal Foods
Anti Oxidant Rich
High Fiber
Alkaline
Cholesterol Free
Anti Inflammatory
Phytonutrient Rich
Balanced /HealthyMacronutrients
Michael Greger: www.nutritionfacts.org
DesirableCharacteristics:
Plant Foods Animal Foods
Anti Oxidant Rich
High Fiber
Alkaline
Cholesterol Free
Anti Inflammatory
Phytonutrient Rich
Balanced /HealthyMacronutrients
AVERAGE CHOLESTEROL LEVELS
150
100
50
200
Pygmy Rural Rural AmericansChina Africa
GOAL
DesirableCharacteristics:
Plant Foods Animal Foods
Anti Oxidant Rich
High Fiber
Alkaline
Cholesterol Free
Anti Inflammatory
Phytonutrient Rich
Balanced /HealthyMacronutrients
Plant Foods: Anti-Inflammatory
• Anti-Oxidant Rich
• Support Healthy Microbiome
• Phytonutrient Rich
Animal Foods: Pro-Inflammatory
• Bacterial Endotoxins
• Heme Iron
• Aracidonic Acid
• Carnitine and Choline TMAO
Heme Iron Linked with: Diabetes -- Up 16% per mg Heart Disease -- Up 27% per mg Stroke – Up 16% high vs. low
quintile Cancer – Colon (12%), Breast (3%),
Lung (12%) per mg1) BMC Medicine, 2012; 10:119 2) Eur. J. Nutr. (2014) 53:395-400 3) Stroke, 2013; 44: 334-334 4) Cancer Eipidemiol Biomarkers Prev. 23(1) January, 2014
Heme Iron per 3 oz. Portion:
Clams – 23.8Oysters – 7.8Muscles – 5.7Venison – 2.8Ground Beef – 2.5Lamb Chop -- 2.1
https://hemochromatosishelp.com/heme-iron-vs-non-heme-iron/
INFLAMMATION
Diabetes
Heart Disease
Alzheimer’s
Neuro Degenerative
Auto Immune
Arthritis
Kidney Disease
Cancer
DesirableCharacteristics:
Plant Foods Animal Foods
Anti Oxidant Rich
High Fiber
Alkaline
Cholesterol Free
Anti Inflammatory
Phytonutrient Rich
Balanced /HealthyMacronutrients
Plants Contain Over 30,000 Disease Preventing “Phytonutrients”
Bioflavonoids
Lycopene
Polyphenols
Phytates
Isoflavones
Carotenoids
Retinols
Genistein
Sulphanes
Etc.
DesirableCharacteristics:
Plant Foods Animal Foods
Anti Oxidant Rich
High Fiber
Alkaline
Cholesterol Free
Anti Inflammatory
Phytonutrient Rich
Balanced /HealthyMacronutrients
Animal Foods Unbalanced
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
Optimal Beef Chicken Mackeral
Fats
Protein
CHO
Macronutrient Source: PROTEIN
Animal
• Acidic
• Allergenic
• Pro-Inflammatory:
Interleukins, CRP, Inflammatory Cytokines
• Stimulate IGF-1
Plant
• Alkaline
• Less Allergy
• Anti-Inflammatory
• No IGF-1 Stimulation
Macronutrient Source: FATS
Animal
• Cholesterol
• Saturated
• Trans Fats
• Heavy Metals & Contaminants
Plant
• No Cholesterol
• Less Saturated
• None
• Low Contaminants
Macronutrient Source: CARBS
Animal
• None or Sugar
• No Fiber
• Milk = Lactose / Galactose
Plant
• Rich in Complex
• High in Fiber
• No Lactose, small Galactose
Macronutrient Source
Plant Animal
Protein
Fats
Carbs
DesirableCharacteristics:
Plant Foods Animal Foods
Anti Oxidant Rich
High Fiber
Alkaline
Cholesterol Free
Anti Inflammatory
Phytonutrient Rich
Balanced /HealthyMacronutrients
Plant Foods: Animal Foods:
Health Supporting?
ANIMAL PLANT P
RO
CES
SED
UN
PR
OC
ESSE
D
The “New 4 Food Groups”
Vegetables
Fruits
Whole Grains
Beans
Heart Disease
Diabetes
Stroke
Hypertension
Arthritis
Osteoporosis
Obesity
Chronic Kidney Disease
Breast Cancer
Colon Cancer
Prostate Cancer
Arthritis
Gall Stones
Kidney Stones
Alzheimer's
Diverticulosis
Etc.
“Diseases of Affluence”
“Food Borne Chronic Disease” Heart Disease
Diabetes
Stroke
Hypertension
Arthritis
Osteoporosis
Obesity
Chronic Kidney Disease
Breast Cancer
Colon Cancer
Prostate Cancer
Arthritis
Gall Stones
Kidney Stones
Alzheimer's
Diverticulosis
Etc.
“An Ounce of
Prevention…
Is worth much more
than a Pound of Cure”
Prevention Pays: Seat Belts
COVID-19 as of 5/17/20
World USA Percent of Total
ConfirmedPositive
4.7 Million 1.5 Million 32%
Deaths 312 Thousand 90 Thousand 29%
Population 7.8 Billion 331 Million 4%
“Food Borne Chronic Disease”
Cardiovascular Disease – 1/3 of all US deaths
Diabetes (30M) / Pre-Diabetes (84M)
Approaching 50% of the population
Hypertension -- 1 in 3 adults
Obesity -- 41% with BMI 28 or greater
= 6x increase risk of severe COVID-19
57%32%
11%
% of Calories
Processed Animal WFPB
Standard American Diet (SAD)
PCRM: www.pcrm.org
% of Calories WFPB
10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85 90 95100
RED = Incite and AccelerateOrange = Later, Slower Progression
Yellow = Mitigate and ArrestGreen = Prevent and Reverse
Chronic Disease Risk- Diet
% WFPB
10 15 20 25 30 35 40 45 50 55 60 65 70 75 80 85 90 95100
Diabetes Reversal – Lab Results
12/8/15
HbA1c 11.7
Fasting Glucose 287
Cholesterol 258
Triglycerides 843
Microalbumen 39
Diabetes Reversal – Lab Results
12/8/15 4/19/16
HbA1c 11.7
Fasting Glucose 287
Cholesterol 258
Triglycerides 843
Microalbumins 39
4/19/16
5.6
4/19/16
5.6
102
4/19/16
5.6
102
161
4/19/16
5.6
102
161
262
4/19/16
5.6
102
161
262
16
Type 2 Diabetes
Insulin ineffective
Sugar builds up in blood
Cells are starving…in the face of plenty
Type 2 Diabetes
What is Gumming up the locks?
Intramyocellular Lipid
Chicken
CAUTION…Lifestyle changes can work so well
that you may need to quickly lower your medications to prevent low blood pressure or low blood sugar. Work closely with your doctor as you proceed on this journey.
Dr Neal Barnard: PCRM, 2018
Dr Neal Barnard: PCRM, 2018
US Adults With Diabetes
Key Take Home Point:
Key Take Home Point:Chicken and Cheese arekey drivers of our
Diabetes Epidemic
+ =
Plaque in
Arteries
Reversing Heart Disease…
J Fam Pract. 2014 Jul;63(7):356-364b
Paul Chatlin…
Dr. Kim Williams:Chair of Cardiology,Rush Universityand Immediatepast president ACC
“There are two kinds of Cardiologists in the world: Those who are vegan, and those who haven’t read the data…”
Not “All or Nothing”
No “Threshold Effect”
The more you do – the greater your gain
The earlier you start the better
But it’s NEVER TOO LATE
General Principles:
Kaiser:“Physicians should consider recommending a plant-based diet to all their patients, especially those patients with high blood pressure, diabetes, cardiovascular disease, or obesity.”
When people nourish their mind and body with health supporting Whole Plant Based foods… and avoid toxic animal and processed foods…
They Feel, Look and Perform Better!
Every Day Eating WFPB Saves:
• 1100 Gallons of Water• 45 pounds of Grain• 30 sq. ft. of Forest• 10 pounds of CO2• 1 Animal’s Life
SummaryKey Take Home Points:
3 Stages of a Cancer:
• Incite
• Promote
• Metastasis
3 Stages of a Pandemic:
• Incite – Viral MutationNo Factory Farms
• Promote – Chronic DiseaseWFPB Lifestyle + No Smoke
• Metastasis – Social SpreadStay Home
Additional Resources: PBNSG.org NutritionFacts.org PCRM.org ForksOverKnives.com ChickpeaAndBean.com VegMichigan.org FoodRevolution.org PlantricianProject.org P-POD.org
www.PBNSG.org
Dr. Michael Greger
www.nutritionfacts.org
July 24-26, 2020
www.P-POD.org
Has been in Raleigh, NC
Virtual in 2020!
When you have your Health
you have 1,000 dreams…
And when you don’t, you have one...
Questions?