Actilease®

Releasing micronutrients where they’re neededActilease® is an efficient microencapsulation technology.

Actilease® beadlets combine protection and easy handling of the active in your products, while improving its bioavailability.

For DSM, quality is a way of life. This is the core of Quality for Life™.

Quality for Life™ is the mark of quality, reliability and traceability. It means that DSM customers are getting the best ingredients, knowing the source on which they depend.

Quality for Life™ means sustainability. It symbolizes our commitment to our environment, consumers, our business partners, our people and the regulatory framework that governs our operations.

With the Quality for Life™ seal, we aim to ensure peace of mind for you and for your customers.

Combining stability and bioavailabilityThe Actilease® beadlet contains droplets of micronutrients in a protective food starch matrix, preventing tabletting losses and interactions with other compounds. Superior stability and a very low extrusion loss allow lower overages and smaller tablets. Meanwhile convenient handling characteristics are provided by the low hygroscopicity, excellent flowability and uniform particle size.

As consumer awareness about bioavailability grows, so does the need for more bioavailable ingredients and product forms. The Actilease® beadlet doesn’t just provide unrivaled protection for micronutrients, it actively releases them, too. When the beadlets reach the stomach, the protective matrix dissolves, releasing the micronutrient droplets, allowing them to be absorbed by the body.

This information is based on DSM’s current knowledge and only contains scientific and technical information for business to business use. DSM makes no representation or warranty of the accuracy, reliability, or completeness of the information and as to results to be obtained. Use of this information shall be at your discretion and risk. It does not relieve you of your obligation to comply with all applicable laws and regulations and to observe all third party rights. Nothing herein relieves you from carrying out your own suitability determinations and tests including the stability testing of the finished product. Country or region-specific information should also be considered when labelling or advertising to final consumers. The content of this document is subject to change without further notice. All trademarks listed in this brochure are either registered trademarks or trademarks of DSM in The Netherlands and/or other countries.

H0238 © DSM Nutritional Products Ltd 2015

Actilease®

For more information on Actilease®, visit www.dsm.com/human-nutrition or e-mail info.dnp@dsm.com

Actilease® beadlets have been meeting this requirement for decades. They contain micro-sized particles of lipophilic substances in a water soluble shell which combine high bioavailability with excellent stability, for more efficiency.

You’ll be finding the Actilease® beadlet technology in following product formulations:

Lowest stability loss of tablets resulting in

long shelf life

Dust-free powder with good

flowability

Superior disintegration leads to best dissolution making the active

available for human absorption

BEADLET

Plas

ma

lute

in (µ

M)

Time (days)

Actilease® FloraGLO® lutein

Competitive lutein

0.50

0.40

0.30

0.20

0.10

0-2 -1 0 1 2 3 4 5 6 7

*Time-course of plasma lutein concentrations (mean±SEM).Single doses of 20 mg lutein were ingested at time point zero.

Bioavailability of lutein from Actilease® beadlet is higher

FloraGlo® is a trademark of Kemin Industries Inc.