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7/31/2019 Regeneration and Repair
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REGENERATION AND REPAIR
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HORMONES = estrogen, progesterone, somatotropin, insulin
EGF bFGFPDGF VEGF
IL-1 and IL-2 TNF
TIGF NGF
Macrophage Derived Growth Factors
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SEEN IN: Cell Surfaces, Basement Membranes and
Pericellular Matrices
MADE BY: Fibroblasts, Endothelial Cells and Monocytes
IN WOUND HEALING
Facilitate migration of epithelium
Chemotactic for monocytes
Chemotactic for fibroblasts
Stimulate endothelial migration and
organization
Release bFGF from monocytes
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