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Reference Text Searching in SciFinder n hbz Online Meeting, June 29 th 2020 CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved. Your SciFinder n team Team contact: [email protected]

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Reference Text Searching in SciFindern

hbz Online Meeting, June 29th 2020

CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved.

Your SciFindern team

Team contact: [email protected]

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Agenda

• Introduction

• Natural language searching

• Operators and truncation

• Informed searching

• Handling results

2CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved.

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Agenda

• Introduction•

3CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved.

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SciFindern‘s reference search process

CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved. 4

Indexed Concept

Chemical name

Separator

Relevance ranking

Keyword

Result listSearch process

Keywords are meaningful words used by authors or inventor in their titles and abstracts. Sometimes an author may select the same words that match a CAS Concept and sometimes they call it slightly differently 

Concept terms are intellectually selected by CAS scientists to systematically capture relevant aspects of the publication

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Search example:PLA nanoparticles for drug delivery

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Polymer capsule

Inner core

Drug or drug conjugate

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Agenda

• Introduction

• Natural language searching•

6CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved.

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Search example: PLA nanoparticles for drug delivery Natural language search without operators or phrase search qualifiers

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Clearly the first hit is very relevantAlmost 100k answers found

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Why is this among the top records?

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'Drug delivery systems' exists as a concept

This concept is a subcategory of 'drug delivery systems'

Also 'nanoparticles' is part of the indexing

2 distinct keywords appear in the title

'PLA' found the chemical name, so substances show a hit as well

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The algorithm will find less relevant results too

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The drug concept indexing was hit, though only one of the two query terms from ‘drug delivery‘ was found

‘pla‘ also found substance names for polylactic acid, registered via the monomer as well as the structural repeating unit.

The nanoparticle search concept and delivery aspect were not found.

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Why do substance roles appear?

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As 'pla' is not identified as a concept or part of it, the search is extended to chemical names. Searching 'pla' as a substance name reveals what is searched behind the scenes. Publications with indexed polylactic acid will be retrieved without deliberately searching chemical names.

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Roles are linked to substances or substance classes

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Biological StudyAssigned to a substance in studies of the role of the substance in or its effect on biological molecules and systems (including organisms, organs, cells, and subcellular systems). Includes aspects such as metabolism, toxicity, occurrence, biological applications and composition.

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Get to know concepts which we retrieved with our search query

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Nanoparticles, pharmaceutical nanoparticles and drug delivery systems are among the top 5 concepts.

We found several very relevant nanoparticle‐related concepts

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Are there further relevant concepts?

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13

nano*Use wildcards within the search tab to find concepts containing words starting with 'nano'

If regarded as relevant we can consider searching nano* or remove this search concept from the basic query in a 2nd approach incl. operators and truncation

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Agenda

• Introduction

• Natural language searching

• Operators and truncation•

14CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved.

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Boolean operators

• Use parentheses to group logical expressions such as OR‘ed synonyms:(artificial or replacement) and skin

AND requires both concepts to be present within the document

OR requires either one or both concepts to be presentConnect synonyms with OR

NOT excludes documents from an answer setBe careful when using the NOT operator, you cannot always assess the context of document texts

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A AND B

A OR B

A NOT B

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Phrase Search and truncation

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• Terms enclosed in double quotes will be searched in the input orderE.g.: "drug delivery"

• Internal and right-hand truncation is available* replaces 0 to any number of characters? replaces 0 or 1 character

• Example for utilizing wildcardshemicellul* hemicellulose, hemicellulosic, hemicellolytic, hemicellulases

Please type special characters such as "" in SciFindern directly

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Agenda

• Introduction

• Natural language searching

• Operators and truncation

• Informed searching•

17CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved.

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Informed searching: Create a more focused basic result set

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(pla or polylactic*) and ("drug delivery" or "pharmaceutical nanoparticle")

Very common term in scientific and patent publications. Also retrieves a series of highly‐relevant concepts,. e.g.:‐ Drug delivery systems (4.7k)‐ Controlled‐release drug delivery systems (3.7k)‐ Targeted drug delivery systems (1,016)

Finds text hits and SRU and monomer‐related polylactic acid registrations

"Pharmaceutical nanoparticle" encodes the drug and the nanosize aspect, so should be searched as a separate keyword

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Load More Results – Best Practice

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Natural language search: No necessity to Load More Results

Informed search: Load More Results!

Δ ~ 80k answers!Several search concepts missing in these answers

Δ < 1k results, butrelevant answers

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Filters are related to an answer set and will disappear when not part the answers

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All PLA‐related search aspects are also reflected in CAS roles, i.e.:‐ Biological studies‐ Nanoscale‐ (Pharmaceutical) Uses

Av. at my institution allows to limit to directly available papers

If we indexed formulations, their purpose is available as a filer too

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Use concepts for refining

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Use search within for most comprehensive results

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Exclude chitosan from your results: Option 1 – NOT

CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved. 23

(pla or polylactic*) and ("drug delivery" or "pharmaceutical nanoparticle") not chitosan*

(pla or polylactic*) and ("drug delivery" or "pharmaceutical nanoparticle")

(!) Issue: A new search has to be initiated, filter settings will be lost

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Exclude chitosan from your results: Option 2 – Search Within: NOT

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Repeat parts of the query present in all answers, then add NOT

(!) Do not start Search Within queries with an operator

This way, you can keep filter settings but still limit results

The term is required rather than excluded, e.g. AND is used

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Exclude chitosan from your results: Option 3 – Combine

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(pla or polylactic*) and ("drug delivery" or "pharmaceutical nanoparticle") chitosan*

1 2

Save searches first Perform search and save query

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Exclude chitosan from your results: Option 3 – Combine (cont.)

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Exclude chitosan from your results: Option 3 – Combine (cont.)

CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved. 27

This combined set can be saved as well

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Focus on patents related to sustained-release nanoparticles

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Open detailed record in new browser instance, e.g. by ctrl+left clicking on title

You can add max. 3 Search Within refinements 

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Display indexed locations of substances with PatentPak

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Click PatentPak link below substance of interst to jump to the location of this specific  compound 

Click any desired PatentPak link from the bibliographic details

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The Interactive Viewer shows this biodegradable polymer is claimed

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Want to kow more about the polymer defined in claim 1? Just scroll up.

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Further PatentPak options

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. . .

. . .

PDF+ contains a table of indexed substances and substance markers in the text

PDF is the plain full‐text. Both PDFs are text‐searchable.

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Search structure and text simultaneously

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Make sure you search references

As Drawn or Substructure results  can be selected after the search

Further polymers are retrieved

The application will be defined by our text search

Different stereoisomers of polylactide are retrieved with the structure search Using polylact* instead of polylactic* in our text search would find the most common polylactide‐related publications

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Advanced Search

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Click link to open Advanced Search page

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Agenda

• Introduction

• Natural language searching

• Operators and truncation

• Informed searching

• Handling results

34CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved.

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Dowload results, share results, create alert

CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved. 35

File Type and Display detail selection define which sections are exported

Limits: xlsx, .ris, .txt,  Up to 1000 results

Limits: .rtf, .pdfSummary = up to 1000 resultsDetails = up to 100 results 

Select Result Details to add further record sections

Checkmark records prior to downloading, sharing or saving to keep only the these references

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Share results and Save/Create alert

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'Email Results' pastes the link to the results of the search query to your default email application

Save allows you to save the search query and set up an alert. 'As available' will be as frequent as every database update

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Coming end of July: CAplus and Medline records will be merged

CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved. 37

For identical publications only one record is available, indicated by 'CAplus and MEDLINE'

CAplus Concepts as well as Medical Subject headings from MEDLINE are available in the unified record

Both IDs appear

Bibliographic datamostly  comes from CAplus

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Summary

• SciFindern's system power allows to start with millions of answers and refine results sequentially

• Natural language searches include relevant results but may lack precision• Logical operators, phrase search and wildcard qualifiers allow to

create precise text queries to find more relevant answers• Concepts are an ideal tool to efficiently focus searches on specific scientific

areas• Simultaneous structure and text searching exploits the value of substance

indexing and text retrieval capabilities with a single search

CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved. 38

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Reference Text Searching in SciFindern

hbz Online Meeting, June 29th 2020

CAS is a division of the American Chemical Society. Copyright 2020 American Chemical Society. All rights reserved.

Your SciFindern team

Team contact: [email protected]

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Thank you for your kind attention- additional resources/support

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• Videos:– SciFinder-n short trainings (Ø 10-15 Minutes recorded)

• https://www.cas.org/hbz/schulungseite– SciFinder-n extended trainings (Ø 30 Minutes recoded- life sessions with Q and A)

• https://www.cas.org/about/events/scifinder-webinars• PDF material:

– SciFinder-n quick reference card• https://www.cas.org/sites/default/files/documents/SciFinder-n-ReferenceCard-HBZ.pdf

– Differences SF Web and SciFinder-n incl. examples for all science areas• https://www.cas.org/sites/default/files/documents/HBZ-online-meeting0320final-rev.pdf

– SciFinder-n tutorial in German (big thank you! to the team at Univ Jena!)• https://pinguin.biologie.uni-jena.de/pub3/1SciFinder-n/SciFinderNAnleitung.pdf

For your individual Online training session please contact [email protected] your team, your co-scientists, your students, all of your BS or MS class