Reference population is Europeon men 35-79

Is 42-57% attributable to genetics

12 loci are used to calculate the risk of prostate cancer

Increased risk of prostate cancer = rs1447295

Decreased risk of prostate cancer = rs1447295 fd

Risk of alzeimers for greg = 12.6%

1 snp is used to calculate the risk for this disease. But it has variants.

APOE gene

Greg mendel – haplotype V

Haplotype V originated in Iberia during the ice age

Lily mendel – H3

Haplotype h3 originated from the near east and then expanded throughout Europe toward the end of the ice age.

Greg – haplotype I1 from Europe

Lil does not have a haplotype

Greg Neanderthal ancestry – 2.6%

Lily Neanderthal ancestry – 2.8%

The adh1B gene is on chromosome 4

Accounts for 19 SNPs for the gene

A no call means no call

No call means that it failed.

The snp if located on chromosome 15

Lily has a genotype of AC

Greg has a genotype of AA

Snp rs762551

All

Allele frequency – A – 63%

G – 37%

Genotype a/a = 0.412

Genotype a/c = 0.436

Genotype c/c = 0.152

Africa

0.562

0.438

0.322

0.480

0.198

America

0.758

0.242

0.591

0.334

0.075

Asia

0.673

0.327

0.454

0.437

0.109

Europe

0.680

0.320

0.475

0.410

0.115