Recovered File 1

7/17/2019 Recovered File 1

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L/O/G/O

“Randomized Trial of Occlusive

Wrap for Heat Loss Prevention in

Preterm Infants”



“Randomized Trial of Occlusive Wrap for Heat Loss

Prevention in Preterm Infants”

Disusun Oleh:Fitrianindita

Ridwan Taufk

Pembimbing:

dr. Suherjati Setiyadi, Sp. A

BAGIAN/SMF ILMU !S!"ATAN ANA

FAULTAS !#$T!RAN UNI%!RSITAS MALA"A&ATI

RSU# 'IAMIS (A)A BARAT

TA"UN *+-



Intrdutin

www.themegallery.com

Very preterm infants areparticularly vulnerable to heat

loss because of:

Immature

Keratin deficientskin without

subcutaneousfat

Poor

vasomotorcontrol

increasedsurface area

to bodyweight ratio

Hypothermia has been recognizedas an independent risk factor for death

in newborn infants.




he application of occlusive wrap immediately after birth can reduce immediate postnatal evaporative heat loss.

Cramer et alEvaluated 3 small,randomized controlled trials

and 5 trials using historical controls

that studied the use of occlusive wra immediately

after !irth in infants !orn

at less than 33 wee"s# gestation.

$he conclution%

&ignificantly reduced the incidence of hyothermia

$he systematic review did not show a significant differencein mortality !etween wraed and unwraed infants.

to determine whether

the use of wraing immediately

after delivery would result in a difference in mortality



Methd0

'yothesized%• ()olyethylene occlusive wra alied immediately

after delivery to infants !orn at *+ /- to *- / -wee"s# gestation would result in decreased mortalitycomared with the conventional method of drying andthermal management.

)articiants%• 0andomized Controlled $rial 10C$2 at 3 articiating

4ermont Oford 6etwor" 14O62 centers 1enrollment

of 78 infants in each grou was lanned2.www.themegallery.com




)rimaryOutcome

9 :ll9cause mortality occurring !efore discharge from thehosital or months# corrected age, whichever camefirst.

9 $rial infants who remained hositalized at months#corrected age were coded as being alive.

&econdaryOutcomes

9 &econdary outcomes included !aseline temeratureta"en after cardioresiratory sta!ilization.

9 ;ncluded :gar scores, ', !ase deficit, and !loodressure and !lood glucose.

9 $he incidence of common comlications ofrematurity were comared.

9 :ll temeratures were aillary and ta"en with astandardized thermometer 1<edline =igital$hermometer, <unde9 lein, ;llinois2.

> !ectal temperatures were optional

and only taken when infants were not wrapped.> "#illary temperature on wrapped infants was taken over the wrap

to prevent opening the wrap and potential cooling of the infant.

> 0esiratory distress syndrome> ?ronchoulmonary dyslasia

> &eizures> )atent =uctus :rteriosus 1)=:2> 6ecrotizing enterocolitis,> Gastrointestinal erforation,> ;ntraventricular hemorrhage,> Cystic eriventricular leu"omalacia,

> )ulmonary hemorrhage,> 0etinoathy of rematurity,> &esis,> )neumothora



&tatistical :nalyses

&tratum 8% *+ /- wee"sto *5 /- wee"s

&tratum *% * /- wee"s

to *- / - wee"s

0esults were reortedwith O0 and their

associated 5@ C;.

&econdary outcomeswere comared !etweengrous using c* analyses

or t tests

:ll analyses used &:&

4ersion .* 1&:& ;nstitute,Cary, 6orth Carolina2 www.themegallery.com



L/O/G/O

hank $ou

$our %usiness &ompany slogan in here

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Recovered File 1