APRI L 2003 ■ VOLUME 13, NUMBER 4

Radiography RevealsMummy’s Secrets

Also Inside:■ PET Shows Promise in Early Detection of AD ■ RSNA Members and Subscribers Have Expanded Access to Scientific Literature■ MR Imaging Advances MS Diagnosis, Treatment■ New Report Released on Diagnostic Ultrasound ■ Mentors Key to Successful Research Career

Advance Registration for RSNA 2003

Begins April 28

RSNA NewsApril 2003 • Volume 13, Number 4

Published monthly by the Radiological Societyof North America, Inc., at 820 Jorie Blvd., Oak Brook, IL 60523-2251. Printed in the USA.

Periodicals postage pending mailing withpostage in Oak Brook, IL 60523, and addition-al mailing offices. POSTMASTER: Send address correction “changes” to: RSNA News, 820 JorieBlvd., Oak Brook, IL 60523-2251.

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Contents of RSNA News copyrighted ©2003 bythe Radiological Society of North America, Inc.

E X E C U T I V E E D I T O RJoseph Taylor

M A N A G I N G E D I T O RNatalie Olinger Boden

C O N T R I B U T I N G E D I T O RRobert E. Campbell, M.D.

E D I T O R I A L B O A R DSusan D. Wall, M.D.

Chair

Lawrence W. Bassett, M.D.Richard H. Cohan, M.D.Nancy A. Ellerbroek, M.D.David S. Hartman, M.D.Bruce L. McClennan, M.D.William T.C. Yuh, M.D., M.S.E.E.Robert R. Hattery, M.D.

Board LiaisonHedvig Hricak, M.D., Ph.D.

Board Liaison-designate

C O N T R I B U T I N G W R I T E R SStephen BarlasDennis ConnaughtonBruce K. DixonAmy Jenkins, M.S.C.Rita LietzMary E. NovakKen SchulzeMarilyn Idelman Soglin

G R A P H I C D E S I G N E RAdam Indyk

A D V I S O R SDave Fellers, C.A.E.

Executive Director

Roberta E. Arnold, M.A., M.H.P.E.Assistant Executive DirectorPublications and Communications

2 0 0 3 R S N A B O A R D O F D I R E C T O R SDavid H. Hussey, M.D.

Chairman

Robert R. Hattery, M.D.Liaison for Publications andCommunications

R. Gilbert Jost, M.D.Liaison for Annual Meeting and Technology

Theresa C. McLoud, M.D.Liaison for Education

Gary J. Becker, M.D.Liaison for Science

Hedvig Hricak, M.D., Ph.D.Liaison-designate for Publications andCommunications

Peggy J. Fritzsche, M.D.President

Brian C. Lentle, M.D.President-elect

Letters to the Editor:E-mail: rsnanews@rsna.orgFax: (630) 571-7837RSNA News820 Jorie Blvd.Oak Brook, IL 60523

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1 People in the News2 Announcements

Feature Articles 4 Radiography Reveals Mummy’s Secrets 6 PET Shows Promise in Early Detection of AD 8 MR Imaging Advances MS Diagnosis, Treatment10 New Report Released on Diagnostic Ultrasound 12 RSNA Members and Subscribers Have Expanded

Access to Scientific Literature

Funding Radiology’s Future17 Mentors Key to Successful Research Career19 Vanguard Spotlight: Siemens Medical Solutions3 Program and Grant Announcements20 R&E Foundation Donors

14 RSNA: Working for You15 Radiology in Public Focus22 Meeting Watch24 Exhibitor News25 www.rsna.org

APRI L 2003

1R S N A N E W SR S N A N E W S . O R G

PEOPLEINTHENEWS

Kington DeputyDirector of NIHRaynard S. Kington,M.D., Ph.D., M.B.A.,is the new deputydirector of the NationalInstitutes of Health(NIH). “I am delightedto have Dr. Kington atmy side as deputydirector during thiscritical time for bio-medical research,” saidNIH Director Elias A.Zerhouni, M.D. “Hehas shown great talentand has the right com-bination of skills andexperience to help theNIH move forward inthese revolutionarytimes for the biomed-ical sciences.”

Dr. Kingtonassumes the position held by RuthKirschstein, M.D., who is now a senior advi-sor to Dr. Zerhouni. Board certified in internalmedicine and public health and preventivemedicine, Dr. Kington has worked for the NIHOffice of Behavioral and Social SciencesResearch and the National Institute on AlcoholAbuse and Alcoholism. He previously servedas director of the Division of Health Examina-tion Statistics at the U.S. Centers for DiseaseControl and Prevention.

Raynard S. Kington,M.D., Ph.D., M.B.A.

Elias A. Zerhouni, M.D.

Jackson Named Interim Chair of RadiologyValerie P. Jackson, M.D., has been named interim chairman of theDepartment of Radiology at Indiana University in Indianapolis. Dr.Jackson, who delivered the Annual Oration in Diagnostic Radiology atRSNA 2002, has previously served as the John A. Campbell Professorof Radiology, director of the radiology residency program and chief ofthe breast radiology section. She is also president of the American Col-lege of Radiology.

Dr. Jackson succeeds Mervyn Cohen, M.B., Ch.B., who resignedthe chairmanship in December but remains in the department as aresearcher and pediatric radiology clinician.

Cox Appointed IMT Director The Academy of Molecular Imaging (AMI)has appointed Kay Cox as director of theInstitute for Molecular Technologies (IMT)—the industry arm of AMI. Cox will work withthe IMT chair and council on the growth ofcorporate membership and reimbursementefforts for AMI.

Rohrbaugh Directs Office of Technology TransferMark L. Rohrbaugh, Ph.D., J.D., has been appointed director of theOffice of Technology Transfer (OTT) in the Office of IntramuralResearch at NIH. Dr. Rohrbaugh will oversee the patenting and licens-ing of NIH inventions and will contribute to intramural and extramuraltechnology transfer policy. Before joining NIH in 1991, Dr. Rohrbaughconducted molecular and cell biology research at the University of Min-nesota and at two biotechnology companies in Minneapolis.

Awards for Academic ExcellenceThree radiologists received awards for academicexcellence in February at the Mexican Societyof Radiology and Imaging (SMRI) AnnualCourse of Radiology and Imaging. They are:Kenji Kimura, M.D., of Mexico Alberto Gómez del Campo, M.D., of Mexico,and Francisco Quiroz, M.D., of Milwaukee.

In addition, SMRI instituted named lecturesin honor of J. Manuel Cardoso, M.D., 2002RSNA second vice-president, and Carlos Man-zano Sierra, M.D., in recognition of their accomplishmentsand dedication to the field of radiology.

Kay Cox

J. Manuel Cardoso, M.D.

Valerie P. Jackson, M.D.

2 R S N A N E W S A P R I L 2 0 0 3

PEOPLEINTHENEWS

Slater Steps Down as Assistant Secretary for HealthEve Slater, M.D., is leaving her post asHHS assistant secretary for health. “EveSlater is a relentless advocate for thehealth and well-being of all Americans,”said Secretary Tommy G. Thompson. “Hertireless work on building the issues ofwomen’s health, HIV/AIDS, reducinghealth disparities, vaccinations, patientsafety, quality of healthcare and the use ofinformation technology in healthcarereform will leave a lasting legacy at HHS.”

Prior to serving as assistant secretary for health, Dr. Slaterwas a senior vice-president at Merck Research Laboratories andwas chief of the Hypertension Unit at Massachusetts GeneralHospital. Surgeon General Richard Carmona, M.D., M.P.H.,will be the acting assistant secretary for health during the searchfor a new assistant secretary.

Clancy Named Director of AHRQCarolyn M. Clancy, M.D.,has been appointed directorof the Department of Healthand Human Service’s (HHS)Agency for HealthcareResearch and Quality(AHRQ). The agency isresponsible for supportingresearch designed to improvethe quality of healthcare,reduce its cost, improve patient safety, decreasemedical errors and broaden access to essentialservices. Dr. Clancy, a graduate of Boston Col-lege and the University of Massachusetts Med-ical School, has served as acting director sinceMarch 2002. She is a general internist and healthservices researcher.

New Initiative Aims to Boost Develop-ment of Innovative Medical ProductsThe Food and Drug Administration has announced abroad initiative that will help make innovative medicaltechnologies available sooner while reducing the costsof developing safe and effective medical products andmaintaining the agency’s consumer protection stan-dards. The initiative affects all four FDA productreview areas (drugs, biologics, devices and veterinarymedicine) and will be developed in collaboration withother agencies and expert groups such as the NationalInstitutes of Health.

To view the report, go to www.fda.gov/bbs/topics/news/2003/beyond2002/report.html.

HIPAA Security Rule Takes EffectThe Security Standards of the Health Insurance Portability andAccountability Act (HIPAA) were published in final form in theFederal Register on February 20. All covered entities, includingphysicians who transmit standard transactions such as claims,must comply with the Security Rule by April 21, 2005.

The Security Rule isintended to establish a levelof protection for protectedhealth information focusingon information transmittedand maintained electronically.The Security Rule specifies aseries of administrative, tech-nical and physical proceduresto assure the security of pro-tected health information.Although the previously pub-lished proposed rule includeda standard for electronic signatures, this version of the SecurityRule does not include the electronic signature standard require-ment. A final rule for electronic signatures will be published ata later date.

HIPAA Alert: Compliance date for privacy standard is April 14, 2003.

More Information■ Center for Medicare and Medic-

aid Serviceswww.cms.hhs.gov/hipaa/hipaa2/default.asp

■ American College of Radiologywww.acr.org/dyna/?doc=depart-ments/econ/hipaa/

■ American Medical AssociationHow to “HIPPA” – Top 10 Tips(Free publication)www.ama-assn.org/ama/pub/category/8158.html

SBT Changes Its NameThe Society for Biological Therapy (SBT) has changedits name to the International Society for Biological Ther-apy of Cancer (iSBTc). Michael Atkins, M.D., iSBTcpresident, says the newname better reflects thesociety’s position as aninternational leader in can-cer research and education.

ANNOUNCEMENTS

Carolyn M. Clancy, M.D.Eve Slater, M.D.

Send your submissions for People in the News to rsnanews@rsna.org, (630) 571-7837 fax, or RSNA News, 820 Jorie Blvd., OakBrook, IL 60523. Please include your full name and telephone number. You may also include a non-returnable color photo, 3x5 or

larger, or electronic photo in high-resolution (300 dpi or higher) TIFF or JPEG format (not embedded in a document). RSNA News maintains the right toaccept information for print based on membership status, newsworthiness and available print space.

3R S N A N E W SR S N A N E W S . O R G

ANNOUNCEMENTS

More First-Time Candidates Take ARRT Primary ExamThe American Registry of Radiolog-ic Technologists reports a 9.6 percentincrease in the number of first-timecandidates taking the ARRT primaryexamination during 2002. The mostnotable increases were in radiationtherapy (up 12.6 percent) and radi-ography (up 9.9 percent). A decreasewas noted in nuclear medicine tech-nology (down 5.1 percent).

A total of 9,080 first-time candi-dates took the examination. Thatcompares to 8,287 in 2001.

The full “Annual Report ofExaminations” is available atwww.arrt.org. Click on “Examina-tions” and then “Exam Statistics.”

2002 ARRT Exam Statistics SummaryCANDIDATES 1ST TIME CANDIDATES

ALL 1ST TIME AVG. SCORE PASS RATEExamination:Radiography 10,912 8,168 83.0 88%

Nuclear Medicine Technology 337 260 83.8 90%

Radiation Therapy 863 652 81.4 86%

Total 12,112 9,080

Cardiovascular-Interventional Technology 284 171 77.9 72%

Mammography 1,367 1,085 81.7 86%

Magnetic Resonance Imaging 1,883 1,099 80.1 77%

Computed Tomography 1,864 1,008 80.5 82%

Quality Management 69 42 78.6 71%

Sonography 28 18 70.1 28%

Vascular Sonography 13 10 80.9 80%

Bone Densitometry 214 185 80.0 81%

Total 5,722 3,618

Exam Scores and pass rates are for first-time candidates. (A score of 75 or greater is required to pass.)

RSNA is sponsoring a course for cur-rent and future academic chairs andleaders of private practice groups, July11-13, 2003, in Oak Brook, Ill. Duringthis 2½-day course, you will learnabout issues relevant to future leaders

in radiology, enablingyou to navigate the

obstacles each leader will face. Attendsessions on financial, quality control,billing, compliance and legal issues aswell as general strategies. Didacticmorning lectures are followed by split

interactive breakout sessions for aca-demic or private practice strategic plan-ning in the afternoon on Friday andSaturday.

Register online at www.rsna.org/education/shortcourses

Registration is $695 for RSNAmembers, $275 for RSNA members-in-training and $795 for non-members.For more information, contact theRSNA Education Center at (630) 368-3747 or ed-ctr@rsna.org.

Strategies for Running a Successful Radiology Practice

RegisterOnline!

RSNA:PROGRAM&GRANTANNOUNCEMENTS

RSNA is sponsoring this one-daycourse on May 31, 2003, at RSNAHeadquarters in Oak Brook,Ill. Paul J. Chang, M.D., ofthe University of PittsburghMedical Center, will takeparticipants through the process of:• Converting radiologic images into an

electronic format

• Editing images and text using lecturesoftware

• Operating a laptop dur-ing a lecture

Attendees will getpractical hands-on expe-

rience and personal instruction. ThePowerRAD 2003 course includes print-ed lecture notes and CD-ROM soft-

ware. Up to 7.25 AMA category 1 cred-it hours are available.

Register online at www.rsna.org/education/shortcourses

Registration is $199for RSNA members and $239 for non-members. For more information contactthe RSNA Education Center staff at(630) 368-3747 or ed-ctr@rsna.org.

PowerRAD 2003: Digital Image Management and Presentation

Digital Image Management and Presentation

PowerRAD2003: Register

Online!

Continued on page 18

4 R S N A N E W S A P R I L 2 0 0 3

FEATURE:RADIOLOGY

Using modern imaging technology,an international team ofresearchers has uncovered impor-

tant information about a 5,300-year-oldmummified human. The corpse, knownas the iceman, displays strikingly mod-ern anatomic features. The findings arepublished as an “Historical Perspec-tive” in the March issue of Radiology.

Two German hikers discovered theiceman in 1991 in a snowfield in aremote part of the Tyrolean Alps. Theiceman was remarkably intact afterexisting for five millennia covered byice and snow and preserved in a mum-mified state. The body was found facedown, frozen and encased in ice, exceptfor his head, neck, shoulders and upperback. Carbon dating showed the manlived 5,300 years ago. The possessionsfound with him, specifically a purecopper axe, indicate he lived during theCopper Age.

Once the mummy was freed fromthe ice, a team of scientists and radiolo-gists from Austria, Italy and the UnitedStates spent 10 years, from September1991 to June 2001, obtaining imagesusing conventional radiography,portable computed radiography and spi-ral CT.

“The purpose of the investigationwas to obtain standard medical imagesof the iceman using modern imagingmethods and then to interpret theimages in accordance with modernradiologic knowledge about humananatomy and disease conditions,” sayslead author William A. Murphy Jr.,M.D., professor of diagnostic radiologyand John S. Dunn Sr. DistinguishedChair of Radiology at the University ofTexas, M.D. Anderson Cancer Centerin Houston.

“Our aim was to learn as much as

possible about the ice-man through theseimages in a medicallyrelevant context,” Dr.Murphy says. “Theimaging team tried todetermine the basicanatomical features ofthe iceman and inter-pret these features in amanner that wouldreveal as much as pos-sible about the individ-ual, his life, his deathand his journey throughthe 5,300 years follow-ing his death.”

All this was donewithout damaging the remains.

What the Images ShowedThe hot Alpine sun and cold, dry airapparently mummified the corpse,while a glacier provided shelter. Radi-ographic images show evidence ofdegenerative arthritis, frostbite, vascu-

lar calcification, healed rib fractures,hairline skull fractures and a compres-sion deformity of the thorax probablyacquired while he was encased in theglacier.

“The finding ofmost general interestwas the discovery ofan arrowhead in theleft shoulderregion,” Dr. Murphynotes. Evidence of ahematoma in theadjacent tissues wasalso detected. Thesefindings suggest thearrow may havecaused vascularinjury and con-tributed to the ice-man’s death.

“I was veryimpressed that the

iceman was strikingly similar to 21stcentury humans in terms of mostanatomic features and his detectedmedical conditions, such as arthritisand calcified blood vessels. Theseobservations confirmed for me that5,300 years is an extremely short inter-val in terms of human evolution,” hesays. “The iceman is recent in thatregard. Still, the iceman is prehistoricin terms of the written record.”

A Unique MummyThe iceman is unique because no othermummies are known to exist from theCopper Age or earlier periods of humanevolution. “The discovery is even moreremarkable because all soft tissueswere preserved, as contrasted with theusual situation where only partial skele-tons are discovered,” he says.

The mummy was also found withpersonal belongings, including cloth-ing, arrows, a knife and an axe. “Thecombination of an intact human fromthe Copper Age with all his personalpossessions opens the way for a deeper

Radiography RevealsMummy’s Secrets

I was very impressed that the

iceman was strikingly similar to

21st century humans in terms

of most anatomic features and

his detected medical conditions,

such as arthritis and calcified

blood vessels. — William A. Murphy Jr., M.D.

William A. Murphy Jr., M.D.M.D. Anderson Cancer Center

5R S N A N E W SR S N A N E W S . O R G

and richer understanding than everbefore possible of human society dur-ing this period. Avenues of additionalinquiry will continue for years to come.Imaging will provide a means to helpanswer many future questions,” Dr.Murphy says.

When the iceman was alive,humans already lived in communities,knew the principles of agriculture, haddetailed knowledge of their environ-ment and even knew how to smelt cop-per, Dr. Murphy explains. “From thenuntil now, humans have shown relative-ly little anatomical change but haveexhibited rapid technological achieve-ment. Genetically, the iceman is sub-stantially the same as modern man.”

Role of RadiologyRadiography was critical to the studyof the iceman because it was the onlyway to evaluate the mummy in a non-destructive way.

“Radiography revealed normalanatomy and alterations of anatomywith no risk or damage to the mummyor to the scientists studying iceman,”says Dr. Murphy. “It permitted themanufacture of plastic models for addi-tional investigation. In addition, itshowed internal features without needfor an autopsy. Radiography providedinsights for new queries and maps forfuture minimally invasive testing.”

In a larger context, Dr. Murphybelieves that the modern role of radiog-raphy in the evaluation of early manincludes the ability to:• Survey remains nondestructively for

anatomic features• Reveal hidden features or nonhuman

artifacts• Provide maps for future investigations

and methods for precise measure-ments

• Allow comparisons between imagesof similar anatomic sites from varioussets of remains

• Facilitate the development of largedatabases for comparative purposes

Figure 1. Radiograph shows variableshrinkage of the brain. Frontal view ofthe head (obtained on May 25, 1993,with the body in the supine position)shows the shrunken brain surrounded bydura mater (arrows) that did not shrinkas much as the brain did. Note the falxcerebri (arrowheads) within the inter-hemispheric fissure. The brain exhibitsvariable opacity, probably due to varia-tion in the physical and chemical alter-ations that accompanied an intermittentor inhomogeneous mummificationprocess.

Figure 2. Photograph of the mummy’schest and abdomen (obtained in Septem-ber 1991) dramatically illustrates theseverity of dehydration and anterior tho-racic collapse. The ribs have rotated in acaudal direction and are pressed againstthe spine, as is the sternum. The left armis extended across the chest and is heldin that position by the brittle dehydratedand frozen tissues.

Figure 4. Detail of the right hip joint froma transverse CT section (obtained on May3, 1994) shows evidence of osteoarthritis,as manifested by proliferative bone(arrows), osteosclerosis, and small roundsubarticular lucent areas. True joint spacewidth cannot be determined because dehy-dration of the hyaline articular cartilagecaused artificial narrowing.

Figure 3. Detail of the teeth from a later-al radiograph of the skull (obtained onMay 25, 1993) shows that all teeth areworn and flattened, presumably frommechanisms of wear specific to thelifestyle of the iceman. Note absence ofthird molars (X = expected molar posi-tions).

Continued on page 11 (Radiology 2003; 226:614-626) © 2003 RSNA. Reprinted with permission.

6 R S N A N E W S A P R I L 2 0 0 3

PET Shows Promise inEarly Detection of AD

Is positron emission tomography(PET) ready for routine use in thedetection of Alzheimer disease (AD),

and should Medicare reimburse thecosts? As discussion heats up over theissue, those who advocate for PET resttheir case primarily on a November 7,2001, study in The Journal of theAmerican Medical Association (JAMA).Authors of the international study of300 patients conclude, “In patients pre-senting with cognitive symptoms ofdementia, regional brain metabolismwas a sensitive indicator of AD and ofneurodegenerative disease in general. Anegative PET scan indicated that patho-logic progression of cognitive impair-ment during the mean three-year fol-low-up was unlikely to occur.”

PET revealed progressive dementiawith a sensitivity of 93 percent and aspecificity of 76 percent. Amongpatients with neuropathologically baseddiagnoses, PET identified patients withAD and patients with any neurodegen-erative disease with a sensitivity of 94percent and specificities of 73 percentand 78 percent, respectively.

The study isespecially importantbecause the federalCenters for Medicareand Medicaid Ser-vices (CMS) is con-sidering whether topay for this particu-lar use of PET. Earli-er this year, theMedicare CoverageAdvisory Committee (MCAC) recom-mended against approving PET for ADdetection, and a final decision by CMSis pending.

Among politicians advocating forMedicare coverage of PET use in

Alzheimer is U.S. Senator Ted Stevens(R-Alaska), who calls Medicare’sreview “an enormous bureaucraticprocess delay” and “a colossal waste oftaxpayers’ money.” Senator Stevensalso says that Medicare approval ofPET diagnosis of AD would stimulatefurther PET research and improve thediagnosis of brain disease.

But a CMSspokesman tells RSNANews, “The JAMAarticle did not demon-strate that theapproved treatmentsfor AD are better aftera diagnosis made witha PET scan versus adiagnosis made in theusual fashion by fol-

lowing guidelines of the AmericanAcademy of Neurology (AAN).”

The Alzheimer’s Association isamong the medical societies wantingmore data before making a final deci-sion. “While we recognize the future

diagnostic potential of PET scans, theirbenefit (in AD) has not been demon-strated or confirmed,” an official state-ment says.

William Thies, Ph.D., vice-presi-dent of medical and scientific affairsfor the Alzheimer’s Association, says,“There may be a small group of indi-viduals who, under certain circum-stances or unusual symptoms that areconfusing the diagnosis, might be can-didates for diagnosis using PET.”

He adds that there is no consensuson patient profile or circumstances. Theassociation says the soon-to-be pub-lished “Report of the NeuroimagingWorkgroup of the Alzheimer’s Associa-tion Concerning the Use of MRI andPET for Clinical Diagnosis and Investi-gation of Cognitive Impairment andDementia” may shed further light onpatient parameters.

The Alzheimer’s Association saysits position is reinforced by clinicalpractice guidelines of AAN, which sayfurther studies are needed before rou-

FEATURE:HOTTOPIC

Gary W. Small, M.D.UCLA Center on Aging

R. Edward Coleman, M.D.Department of Nuclear MedicineDuke University Medical Center

PET does have a major

impact before a clinician can

make a diagnosis of AD in

clearly defined patients with

early stage problems.—R. Edward Coleman, M.D.

7R S N A N E W SR S N A N E W S . O R G

tine use of PET can be recommended.However, the AAN assessment andconclusion were published in May2001, six months before the reportappeared in JAMA.

Researchers at the University ofCalifornia Los Angeles (UCLA) and atDuke University Medical Center saythey are convinced that the data pub-lished in JAMA justify routine, earlydetection of AD with PET, and theystrongly disagree with those who saythe issue is moot because “nothing canbe done for these patients anyway.”

Gary W. Small, M.D., director ofthe UCLA Center on Aging and one ofthe authors of the JAMA study, says thesuperior performance of PET can pindown the presence of dementiamonths—even years—ahead of con-ventional clinical diagnosis and givepatients valuable extra months of inde-pendent living.

“There are four FDA-approveddrugs for AD which have been shownin clinical trials to help with memoryand cognition. They can keep you outof a nursing home for an additionalyear,” says Dr. Small. “The drugs helpwith behavior and overall functioning.There are studies showing that after ayear, patients taking a cholinesteraseinhibitor will be at the same level,while those that don’t take the drugcontinue to slide.”

He adds that patients treated at veryearly PET-detected stages of AD couldeven stay with their jobs longer.

R. Edward Coleman, M.D., a pro-fessor of radiology and director of theDepartment of Nuclear Medicine atDuke University MedicalCenter, says early diagno-sis of AD enables patientsto be more involved inplanning their own lives.“It’s clearly shown thatsome of the new treat-ments, particularly thecholinesterase inhibitors,slow the progression ofdisease and keep patientsin the community longer.

Also, PET can rule out other causes ofdementia. So despite what critics say,there are clear reasons to make a diag-nosis of AD early. PET does have amajor impact before a clinician canmake a diagnosis of AD in clearlydefined patients with early stage prob-lems.”

Dr. Coleman, who helped to gatherand assemble data used to prepare theJAMA article and who is a consultant tothe editor of the RSNA journal Radiol-ogy, adds, “I think radiologists areinterested in providing the best care

they can for their patients.They aren’t getting paidmuch for reading PETscans. They get $80 or$90 to read a scan. PET isnot easy to interpret—ittakes a lot of time.”

Dr. Small concludesthat the benefits of earlyAD detection with PETextend deep into the livesof patients and their fami-

lies, “The point of diagnosis is not justto help with treatment—there are alsoother benefits. There have been studiesshowing that the relationship betweencaregivers and patients actuallyimproves when there is an accuratediagnosis.”

He adds that it’s a myth that AD isa totally negative experience: “Care-givers become more empathic and I’vefound that patients and families stopdoctor shopping and going from clinicto clinic. There’s a sense of relief whenthey get an accurate diagnosis. Eventhough it’s not great news, there is lessuncertainty and a sense of how to moveforward.” ■■

More information:■ JAMA Study Abstract

jama.ama-assn.org/issues/v286n17/abs/joc10908.html

■ Alzheimer’s Associationwww.alz.org

A PET study of glucose metabolism in Alzheimer disease. The “early Alzheimer” studywas performed at the stage of questionable Alzheimer disease and illustrates thecharacteristic metabolic deficits of Alzheimer in the parietal and temporal memorycenters of the brain (arrows). Over time, the metabolic deficit spreads throughoutthe brain. At the late stage of disease, metabolic function of the brain in Alzheimeris similar to that of the newborn shown to far right, which corresponds to their similar behavior and functional capacity. Images courtesy of Drs. Daniel Silverman, Gary Small and Michael Phelps from The David Geffen School of Medicine at UCLA.

PET Study of Alzheimer

Normal Early Late Child

8 R S N A N E W S A P R I L 2 0 0 3

MR imaging has made a signifi-cant impact on the ability todiagnose and treat multiple

sclerosis (MS)—the most commonlydiagnosed neurological disorder inyoung adults.

“Radiology did not play much of arole in treating or evaluating MS priorto MR. Some diagnoses of multiplesclerosis could be made with comput-ed tomography, but MR dramaticallyincreased the sensitivity and specifici-ty,” says Robert I. Grossman, M.D.,the Louis Marx Professor and chair-man of the Department of Radiologyat New York University School ofMedicine.

MS affects 250,000 to 300,000Americans, with 200 new cases diag-nosed weekly, according to the Nation-al Institute of Neurological Disordersand Stroke (NINDS).

MS is a life-long chronic diseasethought to be an autoimmune disorder.During an MS attack, patches of thecentral nervous system’s white matterbecome randomly inflamed causingpartial destruction of insulation aroundthe nerve fibers, or myelin, of thebrain and spinal cord. Unfortunatelyno single test can unequivocally diag-nose MS because many other diseaseshave similar symptoms.

“Radiology is used to image thespinal cord disease, gauge brain atro-phy and study the brain’s biochemistryas well as to classify MS by contrastenhancement and by a number of othermetrics,” says Dr. Grossman, whotaught a refresher course at RSNA2002 on white matter disease, specifi-cally, the pathophysiology of MS, itsmanifestations and new MR methodsthat have been applied. Dr. Grossman

is also the recipientof a 1999 JavitsNeuroscienceInvestigator Awardfrom the NationalInstitutes of Healthfor his work onMS.

The first symp-toms of MS areoften vision related—blurred or dou-ble vision, distor-tion of red andgreen or blindnessin one eye. MSalso causes muscu-lar weakness, lossof coordination orbalance, numbness or pain, fatigue andslurred speech. Difficulties with atten-tion, concentration, judgment andmemory are experienced by about halfof people with MS. Cognitive and lan-guage abilities are rarely affected.

Although there is no cure, researchsuggests that early treatment can delaydisability by decreasing the assault of

MS on the nervous system. Treatmentsmay either manage symptoms or slowdisease course by decreasing the num-ber and severity of attacks. The threetherapeutic objectives are halting dis-ease progression, preventing or lessen-ing the number of attacks and improv-ing relapse recovery.

During the last decade, the FDAapproved five new therapies as disease

modifying agents—three interferon-betaproducts, glatiramiracetate and mitox-antrone. Beta interfer-ons stop MS lesioninflammation byrepairing the blood-brain barrier andreducing the lesion’sinflammatory process.A patient may experi-ence a combination ofthe following benefitsdepending on whichbeta interferon is pre-scribed: decreasedrelapse rates, increasedtime between relapses,

decreased attack severity and reducednumber of lesions. Glatiramir acetatesuppresses the autoimmune attack onmyelin and decreases severity andrelapse frequency. Mitoxantrone is achemotherapeutic agent that suppress-es autoimmune action thus lesseningthe number of attacks and slowing dis-ease progression. Steroids are also pre-scribed to lessen swelling and inflam-mation, consequently reducing attackduration and damage.

“In 1993, a paper was published inNeurology where they actually utilizedMR as a surrogate marker of treatmentefficacy. That was the first time thatthe FDA used MR imaging to license adrug, in that case interferon beta-1b.Subsequently, most treatment proto-cols for MS require MR evaluation,”Dr. Grossman says.

The behavior of MS during thefirst five years can provide some indi-cation of the future course of the dis-ease. Although there are many vari-

MR Imaging Advances MS Diagnosis, Treatment

FEATURE:MEDICINEINPRACTICE

Robert I. Grossman, M.D.New York University School of Medicine

Most treatment protocols for MS

require MR evaluation.—Robert I. Grossman, M.D.

9R S N A N E W SR S N A N E W S . O R G

ables, prognosis is based upon subcat-egorization and disease course experi-ence.

Multiple sclerosis can be subcate-gorized as:• Relapsing-remitting—unpredictable

relapses with new symptoms orworsening of existing symptoms fol-lowed by partial or total recovery,which may last for months or years.

• Primary progressive—slow onset andsteadily worsening symptoms lackingdistinct attacks. Disabilities accumu-late and may stabilize or continue formonths or years.

• Secondary progressive—relapsing-remitting MS later develops into aprogressive disability frequently withsuperimposed relapses.

• Benign—complete recovery follow-ing an attack or two.

“I think radiology’s potential con-tribution to multiple sclerosis isextremely high. Hopefully radiologywill help subcategorize patients anddetermine what treatments work andwhich do not. MR and MR spec-troscopy are incredibly powerful toolsthat will enable us to determine specif-ic disease burden in patients as well asdetermine who responds and who doesnot respond to a particular therapy andjudge outcome,” Dr. Grossmanexplains.

Diffusion tensor MR, MR spec-troscopy and magnetization transferhelp to subcategorize disease and toassist with reversible versus irre-versible determination as well aschronicle the natural history ofchanges.

The cost of medical care includingrehabilitation and productivity loss isrelatively high because MS afflicts

young adults. NINDS estimates theeconomic burden of multiple sclerosisis in excess of $2.5 billion annually.

Currently, researchers are explor-ing the relationship of MS to theautoimmune system, genetics andinfectious agents. Most likely, manyfactors will be found that contribute todevelopment of MS.

“Research on whole-brain NAA ison the cutting edge. We actually devel-oped a technique to measure the extentof loss in the brain of NAA, which is aneuronal marker. That is very impor-tant in both treatment trials and in thenatural history of disease,” adds Dr.Grossman. ■■

Three-dimensional spectroscopy of an MS patient.Image courtesy of Drs. Robert Grossman and Oded Gonen.

More Information About MS■ National Institute of Neurological

Disorders and Stroke www.ninds.nih.gov

■ Multiple Sclerosis International Federationwww.ifmss.org.uk

■ National Multiple Sclerosis Societywww.nmss.org

■ Multiple Sclerosis Foundationwww.msfacts.org

■ Multiple Sclerosis Societywww.mssociety.org.uk

1H-MRS + NAA heat-map image

Note the damagein the vicinity ofthe visible lesion

10 R S N A N E W S A P R I L 2 0 0 3

FEATURE:HOTTOPIC

The National Council on RadiationProtection and Measurements(NCRP) has just released a 500-

page report on exposure criteria fordiagnostic ultrasound.

The report, written by a group ofnotables headed by Wesley L. Nyborg,Ph.D., professor emeritus of physics atthe University of Vermont, says thereport focuses on two key issuesregarding ultrasound: the impact onbody tissues when gas bubbles fromcontrast agents implode—calledacoustical cavitation—and the associat-ed issue of how tissues are affectedwhen their temperature is boosted as aresult of ultrasound.

The report also underlines a poten-tial safety issue. Morton W. Miller,Ph.D., a research professor in theDepartment of Obstetrics and Gynecol-ogy at the University of RochesterMedical Center and co-author of theNCRP report, says the document flash-es a cautionary yellow light about thepotential health effects of elevated tis-sue temperatures. “The temperatureincrements of modern diagnostic ultra-sound devices fall within the range ofthose already known to cause birthdefects in laboratory animal models,”Dr. Miller states.

“Additionally, the literature in thisarea—hyperthermia and birth defects—provides no indication of whether ornot the data follow simple linear orthreshold kinetics. This is a very majorfinding, and is cause for concern,” headds.

The NCRP report comes at a timewhen the Food and Drug Administra-tion (FDA) is urging against the over-use of sonograms for the sole purposeof keepsake photos of fetuses. TheFDA, as well as the American Institute

of Ultrasound in Medicine (AIUM),advises against the use of ultrasoundfor nonmedical purposes. A patientexplanation sheet, “Why SonogramsShould Be Performed Only When Med-ically Indicated,” is available on theAIUM Web site at www.aium.org/con-sumer/entertainment/handout.pdf forphysicians and sonographers to photo-copy and distribute to patients.

In addition to concerns about whenultrasound should be used, specialtygroups have worried about user compe-tency.

Paul Carson, Ph.D., professor ofradiological sciences in the Departmentof Radiology at the University ofMichigan Medical Cen-ter, says almost everyspecialist using ultra-sound equipment coulduse a refresher course.Dr. Carson also helpedto author the NCRPreport.

Asked to point outa significant passage inthe report, Dr. Carsonturned to page 434, which contains rec-ommendations relating to the responsi-bility of users of ultrasound equipment.The recommendation states using ultra-sound at a mechanical index (MI) ofunder 0.5 and all thermal indexes (TIs)less than 1.0 “poses negligible riskunder most conditions.” But Dr. Carsonnotes that some contrast agents arelabeled with instructions saying theycan be used at MIs as high as 0.8.

Often, but not always, the higherthe MI, the clearer the image will be.

But the higher the MI, the more likelyit is that the agent’s bubbles will col-lapse, potentially causing very smallpoints of high temperature and capil-lary damage. Dr. Carson explains that aradiologist often can get a perfectlyclear image at an MI below 0.5 andsometimes at 0.1. He says the only rea-son to go to higher MIs is when a radi-ologist can’t see the contrast agent andis sure the failure is not due to the col-lapsing of the microbubbles.

Speculation about damage of diag-nostic ultrasound to human tissue inmedical use is just speculation. Thereport’s executive summary states, “Areview of existing human epidemiolog-

ical studies of patientsexamined with ultra-sound leads to theencouraging conclu-sion that these studiesdo not provide suffi-cient justification forfinding ultrasound tobe the cause of any ofthe adverse effectsinvestigated.”

But that comes with a huge caveat.All of the tests referred to were per-formed with equipment manufacturedprior to 1991. That year, in response toa request from AIUM, the FDA beganto allow an eight-fold increase in spa-tial-peak temporal-average (SPTA) inmany ultrasound machines. At the sametime, the FDA began requiring U.S.manufacturers to put an “output dis-play” on machines showing the rise intemperature—or the TI—in the targettissue, such as TIB for bone, or TIS for

New Report Released on Diagnostic Ultrasound

The FDA, as well as the

American Institute of

Ultrasound in Medicine

(AIUM), advises against

the use of ultrasound for

nonmedical purposes.

Editor’s Notes: The NCRP report,“Exposure Criteria for Medical Diagnostic Ultrasound: II. CriteriaBased on All Known Mechanisms,” Report No. 140, is available for $95 at www.ncrp.com or by calling (301) 657-2652 x28.

The RSNA-ACR patient education Web site, RadiologyInfo™ (www.RadiologyInfo.org), includesextensive information about various diagnostic procedures using ultrasound.

11R S N A N E W SR S N A N E W S . O R G

Continued from page 5

• Provide images that permit theinterpretation of features to beshared with other scientists as wellas with the public

As to his personal experiencestudying the iceman, Dr. Murphysays, “It was an incredible privilegeand a singular honor to be asked toparticipate in this scientific investi-gation along with many internationalscientists. The actual study of themany images was exciting and tiringbecause of the intensity of theeffort.”

He adds, “I had a constant senseof awe because the chance that amummy of such antiquity and excel-lent condition would ever be foundwas extraordinarily unlikely,” hesays. “Finally, then as now, I had astrong sense of reverence and pro-found respect for the person I wasstudying.” ■■

Professor Dieter zur Nedden (left), chairman of Radiology II at The University of Inns-bruck, Austria, and William A. Murphy Jr., M.D., study a stereolithographic model ofthe iceman’s skull created from CT data. The photograph was taken in September 1992in Dr. zur Nedden’s office in Innsbruck.

❚Anatomic Variants Discovered in the Iceman■ Frontal bone pacchionian granulations■ Prominent frontal eminences

(supraorbital ridges)■ Diastema

■ Absent third molars■ Eleven rib-bearing thoracic vertebrae■ Transitional lumbosacral segment

soft tissue or TIC for cranium.Ultrasound images have becomemuch clearer but concerns abouthyperthermia in tissues have alsoincreased.

Dr. Miller says an importantpart of the NCRP report is its ref-erence to and emphasis of the factthat there isn’t a “no effect” levelfor hyperthermia. “There are opin-ions on whether or not thresholdsexist with hyperthermia-inducedbirth defects with some strongsupport for a total absence ofthresholds,” says Dr. Miller. “Butthe bald fact is that present dataare insufficient for identifyingwhether or not thresholds exists;there are only opinions on theirpresence or absence.”

The NCRP report says thatheating tissues, especially fetal tis-sue, above an increment of onedegree Celsius is not advised for aperiod longer than 160 seconds.That is a half-degree below therecommendation of the WorldFederation for Ultrasound in Med-icine. Dr. Miller stresses that noone really knows what the correctnumber is: “Four million babiesare born in the United States everyyear. Nearly all are scanned atleast once by diagnostic ultra-sound in utero. Many are scannedmore than once. There is potentialfor ultrasound-induced hyperther-mia-related birth defects.” ■■

Making Sense of TI and MIThermal Index (TI): An estimate of the potential temper-ature increase (in degrees Celsius) within the ultrasoundfield. Since the mathematical model used to derive thethermal index cannot consider all possible clinical vari-ables, the intended use of the index is to provide a rela-tive indicator of potential biological effects due to ther-mal mechanisms.

Mechanical Index (MI): The relative potential formechanical effects. The index is based primarily on thephenomenon of cavitation and considers the biologicaleffects associated with the collapse (implosion) ofmicrobubbles. A microbubble, which can be created andcollapsed by an ultrasound field, is capable of generat-ing extremely high temperatures and causing otherforms of damage when collapsing.

Both the MI and the TI are considered dimensionlessvalues.Courtesy James M. Kofler, Ph.D., AAPM Liaison to the RSNA 2002 Scientific Program Committee.

Radiography Reveals Mummy’s Secrets

12 R S N A N E W S A P R I L 2 0 0 3

FEATURE:MEMBERBENEFITS

RSNA members and subscriberscan take advantage of the fact thatthe world’s largest archive of full-

text life science research is making itquicker and more convenientto keep abreast of the latestresearch in medicine, scienceand technology.

Stanford University-based HighWire Press hasexpanded its content and hasadded new features designedto respond to the needs ofresearchers.

The Web site, launchedin 1995 with online produc-tion of the weekly Journal ofBiological Chemistry, hasassisted in the publication ofRadiology Online (radiolo-gy.rsnajnls.org), Radio-Graphics Online (radio-graphics.rsnajnls.org) andthe RSNA Index to ImagingLiterature (rsnaindex.rsna-jnls.org) since 1999.

The new and expanded featuresavailable to RSNA members and sub-scribers include:• More Content. MEDLINE plus 348

full-text journals are available.• Better Searching. Readers can easily

search available journals by topic orbrowse by topic.

• More Alerting. Users can be alertedto new content that matches their spe-cific interests in HighWire-affiliatedarticles or in MEDLINE.

• Easier Access. More than 473,000free, full-text articles are available.Another 3,000 free articles are addedeach month. For articles that are notoffered for free, readers have accessto abstracts or can view the full articlethrough personal or institutional sub-

scriptions or by pay-per-view access.From the HighWire home page,

highwire.stanford.edu, users canbrowse HighWire-hosted journals,

browse articles or search by topics.Searches can be performed using key-words and the names of authors.

“HighWire Press has opened up anew world of interlinked online infor-mation, not only in radiology, but inrelated fields of medicine,” says AlSimonaitis, RSNA’s online journalmanager.

Of the one million full-text articlesavailable on HighWire Press, more than473,000 are free, including all articlesfrom Radiology and RadioGraphicsthat are two or more years old.

“The articles that are free are clear-ly indicated,” says Richard Newman,associate director for HighWire Press.“The site also has the ability to recog-nize a reader’s location when they per-

form a search, sothat when thesearch results aredisplayed, it indi-cates whether anarticle is free toeveryone or freebecause the read-er is at an institu-tion where a sub-scription isavailable.”

From thehome page,under “BrowseHighWire-hosted

journals,” users can click on “Topic”for a list of topics in the biological,medical, physical and social sciences.Under “Medical Sciences,” they canclick on “Radiology” for a list of radi-ology-related journals and articles ofinterest. The journals are rankedaccording to those publishing most fre-quently on radiology.

“The literature for most large fieldslike radiology is dispersed across manyjournals,” says John Sack, associatepublisher and director of HighWirePress. “In cases like that, the best toolsare usually the alerting services, whichare available via the “My E-MailAlerts” button on the site.”

A user who is interested in bonedensity scans could enter that phrase as

RSNA Members and SubscribersHave Expanded Access to Scientific Literature

If I perform a search within

one of the RSNA journals, I can

be notified the next time some-

thing that satisfies that search

is published.—Richard Newman

13R S N A N E W SR S N A N E W S . O R G

a keyword and the system will alert theuser by e-mail. “The system will notifyyou whenever a new article is pub-lished,” says Sack.

“This capability of being notifiedalso works beautifully for authors,”says Newman. “If you have written anarticle in one of the RSNA journals andyou want to know how important yourarticle is, you can be alerted every timesomebody else cites your article.”

The alerting service is very popular.“I think we have about a million ofthese alerts set up by users of the sys-tem,” says Sack.

After registering for a free accountwith HighWire Press, a user can signup for alerts by clicking on “My E-mailAlerts” on the HighWire Press homepage. RSNA members and other read-ers of RSNA journals can also sign upfor alerts through a content box withinthe journals themselves.

“We try to make sure that wheneverpeople are looking at results, they havethe opportunity to be alerted to futureactivity,” explains Newman. “For

example, if I findan article within anRSNA journal, Ican click on a boxwithin that articlethat says, ‘Alert mewhen this article iscited by someone.’”

“Similarly, if Iperform a searchwithin one of theRSNA journals, Ican be notified thenext time some-thing that satisfiesthat search is pub-lished,” he contin-ues.

Among the journals hosted byHighWire Press, 44 are in the top 100most-cited journals, as ranked by theInstitute of Scientific Information,including The New England Journal ofMedicine and the British Medical Jour-nal. New journal offerings include TheJournal of the American Medical Asso-ciation, the AMA’s Archives journals

and the Annals ofInternal Medicine.

“But probably evenmore important thanadding new journals isthat journals withHighWire are addingback content,” saysSack. “They’re goingback 10, 20, 50, insome cases 100 years,and putting their backcontent online. Andthat’s making this stuffgrow very, very fast.”

“I think the impor-tant thing is that thebest journals are on

HighWire Press,” Sack emphasizes. “Ifa person is going to do literatureresearch, they should start here. Thesite has all of PubMed, plus a millionfull-text articles and features for alert-ing and subject searching.” ■■

John SackHighWire Press

Palm/PDA Service Now Available

HighWire Remote deliverstables of contents, abstracts

and selected full-text materialfrom current RSNA journalissues to hand-held PDAs free ofcharge. Palm OS (PDAs fromPalm, Handspring, Sony, etc.) isnow supported. Support forPocketPCs is under development.If you have a Palm OS PDA, andit is set up to sync with a PC orMacintosh computer, you can tryout the feature. On the HighWiresite (highwire. stanford.edu/),click on “My E-Mail Alerts” andthen scroll down to the “My E-Mail Alerts and PDA Channels”section. Once installed, the appli-cation serves as many journals asthe user selects.

1

2

Click on “My E-Mail Alerts.”

Scroll down to “My E-Mail Alerts and PDA Channels.”

14 R S N A N E W S A P R I L 2 0 0 3

RSNA:MEMBERBENEFITS

Working For You

If you have a colleague who would like to become an RSNA member, youcan download an application at www.rsna.org/about/membership/member-apps.html, or contact the RSNA Membership and Subscription Departmentat (630) 571-7873 or membersh@ rsna.org.

SERVICE TO MEMBERS:Medicine probably has seen more changes overthe past 20 years than in any previous 100-yearperiod. That has changed how radiologists workand how RSNA supportsmembers’ needs. I havealways been impressedthat RSNA’s organizationalstructure, leadership andstaff allow the flexibilityneeded to meet members’changing needs. Success-ful organizations some-times resist change; RSNAinvites it and that is, inlarge measure, the reasonfor RSNA’s continued suc-cess. Through surveys aswell as purchasing behav-ior, members tell us whatthey want. We need tolook, listen and servicetheir needs.

The Marketing andCommunications Depart-ment has a nine-person staff and is involved in all com-munications with members, the media and the public. The department is also responsible for all marketingactivities from creating marketing plans for the variousproduct areas of RSNA and the Research & EducationFoundation, to producing the print pieces to supportthose plans.

WORK PHILOSOPHY:Establish what outcomes you would like to achieve.Plan your work. Build a strong foundation ofresources, labor and procedures. And get the job donecorrectly, on time and within budget. A strong founda-tion, able and willing co-workers and a determinationto overcome obstacles will allow you to successfullycomplete core assignments and will position you toeffectively handle the unexpected.

NEW!

Career ConnectionThe classified advertisement area of RSNA Link has beenreplaced with a larger, more personalized area called CareerConnection (careers.rsna.org). This interactive moduleenables RSNA membersto create and post theirresumes online for free. Italso allows them tosearch for jobs by criteriaincluding keywords, jobfunction, modality, loca-tion and salary.

NEW!

RadioGraphics Simplifies Galley Review for AuthorsRSNA’s Publications Department is mak-ing it easier for authors to review galleysof their manuscripts scheduled for publi-cation in RadioGraphics. Instead of usingthe postal service to deliver edited manu-scripts and author information forms,such as check-off lists, tables and reprint requests, authors nowreceive an e-mail directing them to a secure Web site in whichthey can download the galleys and appropriate forms and faxor mail them back.

RadiologyInfo™ LogoRSNA is offering a print-quality RadiologyInfo™ logo forphysicians to use on their prescription pads or other printedmaterials to remind their patients about the wealth of infor-mation available from the RSNA-ACR patient education

Web site,www.Radiology-Info.org. A logo

is also available to link from a physician’s Web site to Radi-ologyInfo. To download the logos, go to www.Radiology-Info.org/legal/ri-webtns.htm.

As an added benefit, more than 40 radiologic proceduresare available as handouts for physicians to download andreproduce for their patients. To access the handouts, go towww.RadiologyInfo.org/pdf/pdf-menu.htm.

NAME:Joseph A. TaylorPOSITION:Director, Marketingand CommunicationsWITH RSNA SINCE:January 18, 1995

WO

RK

ING

FOR

YO

U P

RO

FILE

15R S N A N E W SR S N A N E W S . O R G

Press releases have been sent to the medical news media for the following scientificarticles appearing in the April issue of Radiology (radiology.rsnajnls.org):

Radiology in Public Focus

JOURNALS

“Dietary Caffeine Consumption and Withdrawal:Confounding Variables in Quantitative Cerebral Perfusion Studies?”

Dietary caffeine consumption andwithdrawal are potential sources

of error in the analysis of functionalbrain imaging studies, according to pre-liminary research.

Aaron S. Field, M.D., Ph.D., andcolleagues from the Division of Radio-logical Sciences at Wake Forest Uni-versity School of Medicine in Winston-Salem, N.C., used quantitativeflow-sensitive alternating inversion-recovery perfusion MR imaging toexamine cerebral blood flow in 20adult caffeine users. The subjectsunderwent the procedure twice—90minutes after ingesting a 250 mg doseof caffeine and on another day afteringesting placebo.

The researchers found that in allsubjects, caffeine reduced cerebralblood flow by 23 percent in the anteriorcirculation gray matter and posteriorcirculation gray matter, and by 18 per-cent in white matter.

They write, “The data argue forspecial efforts on the part of brainimaging researchers to control fordietary caffeine effects in future imag-ing studies. … It should be noted thatwhile this study addressed only caf-feine, future studies might address anumber of other potential confoundersof cerebral perfusion and fMRI experi-ments, including tobacco, alcohol andover-the-counter and prescriptiondrugs.”(Radiology 2003; 227:129-135)

“Dynamic Sonography of the Anterior Band of theUlnar Collateral Ligament of the Elbow in Asympto-matic Major League Baseball Pitchers”

Dynamic sonography can revealabnormalities in the anterior band

of the ulnar collateral ligament (UCL)before symptoms occur.

Levon N. Nazarian, M.D., and col-leagues from Thomas Jefferson Univer-sity Hospital in Philadelphia, studiedimages of the pitching arms and non-pitching arms of 26 asymptomaticmajor league professional baseballpitchers prior to the start of their springtraining.

Previous studies haveshown that most sympto-matic tears are the resultof chronic, repetitive trau-ma.

The current researchshows that in pitchingarms, the anterior band isthicker, hypoechoic fociand calcifications aremore common and theulnohumeral joint widensto a greater degree withvalgus stress.

The researchers write, “This base-line information may be useful in eval-uating acute UCL injuries or acuteexacerbations of chronic injuries.Future studies need to evaluate the rela-tive effectiveness of sonography andMR arthrography.”(Radiology 2003; 227:149-154)

“Upper Airway Motion Depicted at Cine MR ImagingPerformed During Sleep: Comparison BetweenYoung Patients With and Those Without ObstructiveSleep Apnea”

Patterns of dynamic airway motionare significantly different between

young patients with and those withoutobstructive sleep apnea.

Lane F. Donnelly, M.D., and col-leagues from Children’s Hospital Med-ical Center in Cincinnati used cine MRimaging to study 16 children with doc-umented obstructive sleep apnea and 16age-matched control subjects.

They found that the patients withobstructive sleep apneawere much more likelyto demonstrate inter-mittent collapse of thenasopharynx andexclusively demon-strated intermittent col-lapse of the hypophar-ynx. The mean changein diameter of thenasopharynx and thehypopharynx was alsosignificantly greater inthe obstructive sleep

apnea group than in the control group. Obstructive sleep apnea in children

can be associated with excessive day-time sleepiness, hyperactivity, attentiondeficit disorder, poor hearing, physicaldebilitation and failure to thrive. Infor-mation cited in the study says approxi-mately two million children in theUnited States are affected.(Radiology 2003; 227:239-245)RSNA press releases are available at

www2.rsna.org/pr/pr1.cfm.

17R S N A N E W SR S N A N E W S . O R G

RESEARCH&EDUCATION:PROFILE

Mentors Key to SuccessfulResearch Career

When A. Aria Tzika,Ph.D., says she ishonest to her roots,she means it. Thenative of Greece

says, “Like Hippocrates, I am interest-ed in promoting cures and the under-standing of diseases. I’m not in thisfield to make a lot of money.” In orderto succeed in research, she says youhave to have good mentors.

“RSNA has two important roles.One is that of helping to promote aca-demic science and medicine, but I thinkRSNA’s most important role is mentor-ship,” Dr. Tzika says.

Early in her medical career, Dr.Tzika’s research interests focused onbiomedical functional MR imaging andspectroscopy of the brain. She was the1995 Eastman Kodak/RSNA ResearchScholar. Her project was “PediatricBrain Tumor Treatment Evaluated byVolume MRI/MRS.”

Through her research project, shefound that clinical proton MR spec-troscopy and hemodynamic MR imag-ing could add insights into the mecha-nism of neurologic disease, allowearlier diagnosis and provide a non-invasive diagnostic method for follow-up treatments.

Dr. Tzika says all of her researchhas been built upon her initial RSNAinvestigations. “RSNA gave me atremendous opportunity as an earlyresearcher,” she says. In 1998, theAmerican Cancer Society gave her$500,000 to continue her studies. “Istretched that grant out for four yearsuntil June of 2002. I am searching fornew grant money now, but these aredifficult days for funding” she adds.

Dr. Tzika is an assistant professorof surgery at Harvard Medical School

in Cambridge, Mass.She is the director ofthe NMR SurgicalLaboratory and anassistant physiologistin the Department ofSurgery at Massachu-setts General Hospitalin Boston. She alsohas an appointment tothe Shriners BurnsInstitute.

Dr. Tzika, a citi-zen of the UnitedStates and Greece,studied biology inGreece. She conduct-ed her post-graduatework in physiologyand anatomy at the University of Cali-fornia at Berkeley. She was a postdoc-toral fellow at the University of Cali-fornia, San Francisco (UCSF).

Her research these days has shiftedfrom imaging and spectroscopy of thebrain to molecular imaging. She says

she’s thrilled that the National Institutesof Health is promoting studies onmolecular imaging and that the 2003topic of interest for the RSNA FellowGrant is molecular imaging. “Thoseexciting studies will give a lot of

answers to basicresearch questions,”she says.

She’s also con-ducting investiga-tions into pediatricbrain tumors, atten-tion deficit hyperac-tivity disorder and, ata more basicresearch level, therole of mitochondriain pathophysiologicalstates.

“I chose academicresearch, not clinicalradiology, because Iam most interested insolving puzzles of

nature,” she says. Clinical work, to her,is “too routine.” While studying atUCSF, she received a lot of exposureand background in what she needs clini-cally to perform her research.

Years after her work as an RSNAScholar, Dr. Tzika continues to supportthe organization. She was a scientificgrant reviewer for the R&E Founda-tion’s Roster of Distinguished Scientif-ic Advisors and has attended nearlyevery RSNA Scientific Assembly sincethe mid-1980s.

How to Succeed as an Academic RadiologyResearcherWhile she loves her work, Dr. Tzikasays it is not easy to be successful inthis type of career. “It is difficult to sur-vive in academic radiology research. Ittakes a huge commitment and you cer-tainly will never be famous,” she adds.

Dr. Tzika says there are two keys tosuccess, “First, you must have a desireto answer intriguing scientific ques-

RSNA has two important roles.

One is that of helping

to promote academic science

and medicine, but I think

RSNA’s most important role

is mentorship.— A. Aria Tzika, Ph.D.

A. Aria Tzika, Ph.D.1995 RSNA Research Scholar

Continued on next page

18 R S N A N E W S A P R I L 2 0 0 3

tions, even though the answers to those questionsmay never be found in your lifetime. I have been verylucky in my career, but most researchers do not get tosee their questions answered.”

Second, Dr. Tzika says you must identify mentorsearly—in college, medical school or even as an asso-ciate professor. She says this is very important foryoung scientists to understand. “Without mentors,you can forget about your research dreams.”

Thanks to phones, faxes and e-mails, mentors canlive in another country and still be close at hand.“Keep your mentors close to you, especially if youare young. They will protect you from misfocusingand they’ll steer you away from trouble,” she advises.

Dr. Tzika doesn’t just talk the talk. She has hadmentors throughout her life. “Both women and menhave helped me. Each recognized a different charac-teristic in me and pushed me. Sometimes I felt like Ididn’t have any choice. Now I realize I was lucky,”she says.

“I would like to mentor others. This is the bestway for me to repay my mentors,” she adds. ■■

Continued from previous page

RSNA:PROGRAM&GRANTANNOUNCEMENTS

Academic Research Enhancement Award (AREA) NIH is continuing to make a special effort to stimulate research ineducational institutions that provide baccalaureate or advanced train-ing for a significant number of the nation’s research scientists butthat have not been major recipients of NIH support.

AREA funds are intended to support new (“type 1”) and continu-ing (“renewal” or “competing continuation” or “type 2”) health-relat-ed research projects proposed by faculty members of eligible schoolsand components of domestic institutions. To determine the eligibilityof a school or component with regard to this requirement, applicantsshould consult the list of ineligible schools/components on theAREA Web page at grants.nih.gov/grants/funding/area.htm.

• Application Receipt Dates: January 25, May 25, September 25• AIDS-related Application Receipt Dates: May 1, September 1,

January 2

NEW!

BECON 2003 Symposium to Focus on Team Science The Bioengineering Consortium (BECON) of theNational Institutes of Health (NIH) has scheduledits sixth annual Symposium for June 23-24, 2003,at the Natcher Conference Center in Bethesda,Md. The Symposium, “Catalyzing Team Sci-ence,” is aimed at examining the forces thatencourage and discourage team approaches tobiomedical research and exploring ways in whichNIH, academia and others can stimulate andreward team efforts.

A preliminary agenda, along with programand registration information, are available atwww.becon.nih.gov/symposium2003.htm.

Continued from page 3

Options. For life.

North Shore – Long Island Jewish Health SystemAs one of America’s largest health care systems, we are a network of18 hospitals, long term care facilities, trauma centers, and homehealth and hospice agencies, located throughout Long Island,Queens and Staten Island. And this means more options. Moreopportunities. For you. For your career.

Breast Imaging/Women’s Imaging RadiologistThe Department of Radiology is recruiting an additional facultymember to join its breast imaging section. The combined breastimaging centers have eight mammography units, three ultrasoundunits and two stereotactic biopsy devices. Three full field digitalmammography units will be installed. A high volume of breast imagingstudies is performed including mammography, breast ultrasound andbreast interventional procedures. You must be a board-certifiedradiologist preferably with fellowship training or significantexperience in breast/women’s imaging. The department offers anextremely competitive compensation package based on experience.Interested candidates should contact and send CV to: Lawrence P.Davis, MD, FACR, Vice Chair, Department of Radiology, Long IslandJewish Medical Center, 270-05 76th Ave., New Hyde Park, NY 11040Ph: 718-470-7235. Fax: 718-343-3893. E-mail: ldavis@lij.edu

Setting New Standards in Healthcare.

www.northshorelij.com Equal opportunity employer M/F/D/V

Mentors Key to SuccessfulResearch Career

For more information on RSNA R&E Foundation grants,contact Scott Walter at (630) 571-7816 or walter@rsna.org.

19R S N A N E W SR S N A N E W S . O R G

Vanguard Company Spotlight

Siemens Medical Solutions

Siemens MedicalSolutions is demon-strating its continueddedication to the

advancement of radiologic practicewith a $1.5 million pledge to theRSNA Research & Education Founda-tion. The 10-year pledge will endow aSiemens Medical Solutions/RSNAResearch Scholar Award. The firstrecipient will be named later this year.

“RSNA’s leadership role in thefields of scientific research and educa-tion in radiology is crucial to the futureof medicine,” says Thomas N.McCausland, president and chief exec-utive officer of Siemens Medical Solu-tions USA. Siemens previously donated$750,000 in support of the SiemensMedical Solutions/RSNA Research Fel-low Award.

Siemens’ association with theFoundation began in1990 when Siemensbecame a member ofthe RSNA VanguardGroup of companies.Since then, 11 inves-tigators have benefit-ed from Siemens’commitment topatient care. The value of today’sresearch in tomorrow’s practice isapparent in the continuing investiga-tions of 1997 Siemens Medical Solu-tions/RSNA Research Fellow PamelaK. Woodard, M.D. She recentlybecame the principal investigator atWashington University of a three-year,eight-center, $13.5 million study fund-ed by the National Institutes of Health(NIH) to assess the accuracy and utilityof multidetector contrast-enhanced spi-

ral CT in searching for pulmonaryembolisms. She is also the co-investi-gator of a $1.5 million NIH grant to

develop and optimizemethods for performingcoronary artery interven-tions under MRguidance.

Bonnie N. Joe,M.D., Ph.D., from theMallinckrodt Institute ofRadiology at WashingtonUniversity in St. Louis, isthe 2002 Siemens Medical

Solutions/RSNA Research Fellow. Dr.Joe is investigating the technical limita-

tions of current contrast-enhancedbreast MR imaging and spectroscopyand determining how to improve thesetechniques.

Siemens Medical Solutions is aleading supplier of integrated clinical

and IT solutions tothe healthcareindustry. From

imaging systems for use in diagnosis,therapy and treatment to IT solutionsthat increase clinic, office and hospitalefficiency, Siemens’s innovative prod-ucts and services effectively addressthe challenges that the medical commu-nity faces daily. Siemens strives to havea positive impact on a person’s lifelonghealth by creating an efficient health-care system and developing equipmentthat promotes the best possible patientcare. ■■

RSNA’s leadership role in

the fields of scientific

research and education

in radiology is crucial to

the future of medicine.—Thomas N. McCausland

For more information on the RSNAResearch & Education Foundation grantprograms, contact Scott Walter at (630)571-7816 or at walter@rsna.org.

For more information about becomingan RSNA Research & Education FoundationVanguard Company, contact Deborah Krollat (630) 368-3742 or dkroll@rsna.org

RESEARCH&EDUCATION:PROFILE

Siemens Medical Solutions has pledged $1.5 million in additional contributions to theRSNA Research and Education Foundation.

20 R S N A N E W S A P R I L 2 0 0 3

RESEARCH&EDUCATION:OURFUTURE

Research & Education Foundation Donors

Hans D. Rigauts, M.D.Anne C. Roberts, M.D. & John Arnold,M.D.

William D. Routh, M.D.Maryanne Ruggiero-Delliturri, M.D.Kamal B. Russell, M.D.Sadayuki Sakuma, M.D., Ph.D.Mohammad Sarwar, M.D.Michael J. Shanks, M.D.W. Sean Smith, M.D.Valery P. Sobczynski, M.D.Marie V. Spagnoli, M.D.Michael E. Spieth, M.D.Andrew P. Spillett, M.D.Leo J. Spittler, M.D.Martin Steinhoff, M.D.Troy F. Storey, M.D.Arnold M. Strimling, M.D.Steven J. Strober, M.D.Rowena G. Tena, M.D., M.P.H.William T. Thorwarth Jr., M.D.Rommel G. Villacorta, M.D.Kay H. Vydareny, M.D. & WilliamCasarella, M.D.

Simona Waldmann, M.D.Steven F. Waslawski, M.D.W. Richard Webb, M.D.Jerold B. Weinberg M.D.William C. Werthmuller, M.D.Bruce W. White Jr., M.D.Jonathan I. Wiener, M.D.Timothy J. Woisnet, M.D.Wen C. Yang, M.D.Dieter zur Nedden, M.D.

Todd M. Hertzberg, M.D.Brooks A. Horsley, M.D.Dorothy & Frank L. Hussey Jr., M.D.Eric D. Johnson, M.D.John O. Johnson, M.D.Bronwyn Jones, M.D.Stephen B. Kelminson, M.D.Rita M. Kikkawa, M.D.Nicholas C. Kinnas, M.D.Edmond A. Knopp, M.D.Sandra J. Knuth, D.O.Mark J. Kransdorf, M.D.Ronald D. Kunst, M.D.Yen-Zen Kuo, M.D.Faye C. Laing, M.D.Dong-Kyu Lee, M.D.Li Liu, M.D.Arthur G. Livingstone Jr., M.D.Joseph W. Lowry, M.D.Paul A. Lyle, M.D., Ph.D.Tor A. Mattsson, M.D., Ph.D.Patrick L. McCarthy, M.D.Michelle M. McNicholas, M.D.Rui Augusto Corga P. Melo, M.D.Ralph W. Mutchler Jr., M.D.Jean N. Nauwelaers, M.D.Paul A. Neese, M.D.Njideka H. Nyako, M.B.B.S.Kazuyuki Ohgi, M.D.Harvey PickerStuart W. Point, M.D.George M. Prackup, M.D.Gautham P. Reddy, M.D.John H. Rees, M.D.

PLATINUM ($1,000 - $4,999)RSNA

SILVER ($200 - $499)Stephen A. Agatston, M.D.Farida Ahmed, M.D.R. D. Anderson, M.D.Muhammed S. Anwer, M.D.Mohammad Athar, M.D.Richard L. Baron, M.D.Stanley Baum, M.D.Javier Beltran, M.D.Beryl R. Benacerraf, M.D.Paul A. Bilow, M.D.Erik Boijsen, M.D.Leonard R. Bok, M.D., M.B.A.Morton A. Bosniak, M.D.Juergen Brandt, M.D.Stuart E. Braverman, M.D.Michael P. Breen, M.D.Earl R. Brown Jr., M.D.Paul Capito, M.D.Anthony R. Carter, M.D.Robert L. Chiteman, M.D.John V. Cholankeril, M.D.Winston F.B. Clarke, M.D.David P. Colley, M.D.Ira Lee Cox III, M.D.Tommy E. Cupples, M.D.Carol Anne Dolinskas, M.D.Paul H. Dombrowski, M.D.Jerome Dubowy, M.D.Connie L. Emerson, M.D.Erwin H. Engert Jr., M.D.Edrick J. Ferguson, M.D.Pablo A. Gamboa, M.D.Richard H. Gold, M.D.David Goldblatt, M.D.Nancy J. Goldenberg, M.D.Robert B. Golson, M.D.Patricia E. Grant, M.D., M.Sc.Julius Harry Grollman Jr., M.D.Giuseppe Guglielmi, M.D.William J. Halden Jr., M.D.John A. Harding, M.D.Joseph H. Harpole Jr., M.D.Linda A. Heier, M.D.

BRONZE ($1 - $199)German G. Abdo Sarras, M.D.Bibb Allen Jr., M.D.John E. Antoine, M.D.Ronald C. Arildsen, M.D.Craig E. Barnes, M.D.Stephen A. Barrand, M.D.Patricia A. Barry, M.D.Daniel D. Beineke, M.D.Gerald A. Black, M.D.David A. Bluemke, M.D., Ph.D.Michael R. Brand, M.D.Stephen M. Bravo, M.D.Joffa L. Braymer, M.D.George J. Broder, M.D.Lynn S. Broderick, M.D.Ligia Cardona, M.D.Nils-Olov Carlsson, M.D.Evan F. Chambers, M.D.Veena Chandler, M.D.Yeun-Chung Chang, M.D.F. Spencer Chivers, M.D.Haesun Choi, M.D.Ross A. Christensen, M.D.Geoffrey D. Clarke, Ph.D.Jeffrey R. Conaway, M.D.Benjamin F. Cowan, M.D.Francisco O. Cruz, M.D.Kirkland W. Davis, M.D.Carlos F. De Pierris, M.D.Marconi R. Deladisma, M.D.Charles J. DeMarco, M.D.Thomas A. Demlow, M.D.Leif A. Ekelund, M.D.Lorenzo M. Farolan, M.D.Jose L. Ferreira, M.D.Angela J. Feyerabend, M.D.Gerardo M. Figueroa Sanchez, M.D.Joel G. Fletcher, M.D.Stacey A. Funt, M.D.Richard Ghavami, M.D.Raymond A. Gibney, M.D.Josef K. Gmeinwieser, M.D.Damien F. Goudot, M.D.W. Lawrence Greif, M.D.G. Christopher Hammet, M.D.Sue E. Hanks, M.D.

THE BOARD OF TRUSTEES of the RSNA Research & Education Foundation and its recipientsof research and educational grant support gratefully acknowledge the contributions made

to the Foundation between January 31, 2003 and February 27, 2003.

$10,000Vanguard Company since 2000

William M. Angus, M.D., Ph.D.Jonathan Breslau, M.D.Ferenc A. Jolesz, M.D.Marten KlopSolveig & Seymour H. Levitt, M.D.Ingrid & Patrick C. Seynaeve, M.D.

RSNAPRESIDENT’S CIRCLE MEMBERS$1,500 per year

VANGUARD GROUPE-Z-Em, Inc. Alliance Imaging

$15,000

Hologic

$10,000

IGC–Medical Advances

$5,000

EXHIBITOR’S CIRCLE

21R S N A N E W SR S N A N E W S . O R G

Jerome M. Sampson, M.D.Michael A. Sandler, M.D.Larry A. Schwartz Jr., M.D.Lewis I. Segal, M.D.Peter M. Selzer, M.D.Ulf Settergren, M.D.Dipakkumar S. Shah, M.D.William B. Shelton, M.D.Harry S. Shulman, M.D.Ellis L. Silberman, M.D.Suzanne J. Smith, M.D.Nathan Stofberg, M.D.Shoichi D. Takekawa, M.D.Judy K. Tam, M.D.Michael S. Tenner, M.D.Eva Tlusty, M.D.Huan N. Tran, M.D.Jacqueline A. Treschuk-Bahn, M.D.Sabah S. Tumeh, M.D.Helmut G. Unger, M.D.Cornelis F. Van Dijke, M.D., Ph.D.Francisco C. Vargas, M.D.

Gerard J. Murphy, M.D.Kyung J. Nam, M.D.Michael T. Nelson, M.D.Paul T. Niland, M.D.Ron O. Norman, M.D.Wayne J. Normore, M.D.Stephen C. O’Connor, M.D.Reed A. Omary, M.D., M.S.Gustav H. Ooms, M.D.Kazuyuki Oyama, M.D.William E. Palmer, M.D.Matthew T. Pardy, M.D.Mitchell Parver, M.D.Lee J. Phillips, M.D.Marvin Platt, M.D.Thomas F. Pugh Jr., M.D.Nancy L. Putnam, M.D.Robert Rapport, M.D.John M. Rennick, M.D.Melvin J. Richards, M.D.Jaap G. Roukema, M.D.G. Thomas Ruebel, M.D.

Donald R. Hansard, M.D.Curtis L. Harlow, M.D.Richard S. Hartman, M.D.Hiroto Hatabu, M.D., Ph.D.Sergio L. Heredia, M.D.John F. Hiehle Jr., M.D.Pamela L. Hilpert, M.D., Ph.D.Michael T. Hirleman, M.D.Chia-Sing Ho, M.D.Paul Ho, M.D.Evert-Jan M. Imkamp, M.D.Takeshi Johkoh, M.D., Ph.D.Junichi Kageyama, M.D.Donald L. Kahle, M.D.Kishore V. Kamath, M.D.Ruben Kier, M.D.Ray F. Kilcoyne, M.D.Elissa L. Kramer, M.D.George S. Krol, M.D.Wolfgang Lederer, M.D.Hae-Kyung Lee, M.D.Georges B. LeRoux, M.D.Jacques J. Levesque, M.D.Deborah Levine, M.D.Jonathan S. Lewin, M.D.Robert L. Lloyd, M.D.Marcus E. Luetolf, M.D.David J. Lyons, M.D.Frances S. Maeda, M.D.Lee A. Malmed, M.D.Ferdinand L. Manlio, D.O.Klas O. Mare, M.D.James E. McConchie M.D.Jean Y. Meuwly, M.D.Michael J. Morin, M.D.

Lorraine Vazquez de Corral, M.D.Juan D. Vielma, M.D.Otto-Henning Wegener, M.D.Faith A. Weidner, M.D.Michael J. Weiner M.D.Ellen B. Wetter, M.D.Scott D. Wiedenmann, M.D.Francis W. Willi, M.D.Morgan P. Williamson, M.D.Peter W. Wong, M.D.Robert E. Woods, M.D.Wei-Jen Yao, M.D.Tetsuo Yoshida, M.D.Sachiko Yuen, M.D.Christoph L. Zollikofer, M.D.

RESEARCH&EDUCATION:OURFUTURE

BRONZE ($1 - $199), CONTINUED

Robert M. Domke, M.D.In memory of David Millet, M.D.

Jesus D. Guerra, M.D.In honor of Leon Love, M.D.

Leo Hochhauser, M.D.In memory of Derek Harwood-Nash, M.D., D.Sc.

Denton E. MacCarty, M.D.In memory of Robert R. Duhamel, M.D.

Luceil B. North, M.D.In honor of Sandra Oldham, M.D.

Ingrid & Patrick Seynaeve, M.D.In honor of Peggy J. Fritzsche, M.D.

Coralie Shaw, M.D.In honor of Richard H. Greenspan, M.D.

Faith B. & Theodore A. Tristan, M.D.In honor of Adele Swenson

Bonita & David A. Turner, M.D.In memory of Robert T. Turner, M.D.

COMMEMORATIVE GIFTS

Online donations can be made atwww.rsna.org/research/foundation/donation.

Alliance Imaging, Inc., became the firstmember of the new RSNA Exhibitor’sCircle program.

The program enables small- to mid-size companies to annually supportresearch at more modest levels thanthat required for the Foundation’s con-tinuing Vanguard program.

Recognizing the benefits of sup-porting research, Alliance Imagingexpressed interest in joining theExhibitor’s Circle as the program waslaunched at RSNA 2002.

“This program offers the best ofboth worlds to corporate donors,” saysTerry Andrues, Alliance executive vice-president. “Alliance Imaging is able tosupport both our customers and the

radiologic community in tangible waysthat foster responsible corporate stew-ardship.”

Shortly after Alliance’s commit-ment, two other companies joined theExhibitor’s Circle. They are HologicInc., and IGC–Medical Advances Inc.

Benefits of RSNA Exhibitor’s Circle membership include:• Acknowledgment in RSNA publica-

tions including RSNA News, the Buy-er’s Guide, the RSNA MembershipDirectory and the RSNA Research &Education Foundation Annual Report.

• Invitation to a reception forExhibitor’s Circle members andRSNA leaders

• Recognition signs at the Research &

Education Foundation Pavilion• Exhibitor’s Circle signs for exhibit

booth• Special recognition ribbon for corpo-

rate representatives for their annualmeeting badge

Categories• Platinum Circle ($10,000 per year)• Gold Circle ($5,000 per year)• Silver Circle ($2,500 per year)• Bronze Circle ($1,000 per year)

For more information on becoming a mem-ber of the RSNA Exhibitor’s Circle, contactDeborah L. Kroll, Managing Director: FundDevelopment at (630) 368-3742 ordkroll@rsna.org.

New Exhibitor’s Circle Program Adds First Members

22 R S N A N E W S A P R I L 2 0 0 3

MEETINGWATCH:RSNA2003

News about RSNA 2003

Important Dates for RSNA 2003April 15 Deadline for abstract

submission

April 28 RSNA and AAPM member registration/housing opens

NEW May 27 General registration opens

June 23 Course enrollment opens

Oct. 10 Registration deadline forNon-North American partici-pants to have badge walletmailed

Oct. 31 Final advance registrationdeadline

Nov. 30–Dec. 5 RSNA 89th Scientific Assem-bly and Annual Meeting

NEW!

Electronic Only Advance Regis-tration and Housing BrochureThe first advance registration brochure forRSNA 2003 is available only in electronicformat. Instructions on how to access theAdvance Registration and Housing brochurewill be mailed the week of April 21.

The brochure will be posted on RSNALink (www.rsna.org) as a portable docu-ment format (PDF) file and will be avail-able by fax-on-demand.

RSNA LinkGo to www.rsna.org and click on AdvanceRegistration. The brochure is available asa PDF file for you to view, downloadand/or print.

Fax on DemandBeginning April 21, call (847) 940-2146,then enter your fax number and a docu-ment number.• Document 1300: entire brochure• Document 1375: registration form only

In late June, a hard copy of theRefresher Course Enrollment brochurewill be mailed. An electronic version willalso be available by download or fax.Course enrollment begins June 23.

Online (24 hours a day)www.rsna.org/rsna/advanceregistration/Enter your membershipidentification numberfound on the mailinglabel of your accessinstructions or on thecover of RSNA News.The entire process takesonly a few minutes. Ifyou request hotel reserva-tions, a hotel room deposit will becharged to your credit card.

Fax (24 hours a day)(800) 521-6017 (847) 940-2386 outside the United States and Canada

Phone (Monday – Friday, 8:00 a.m. – 5:00 p.m. CT)(800) 650-7018 (847) 940-2155 outside the UnitedStates and Canada

Please be ready to provide the fol-

lowing information:• Registration information (name,

organization, phone, etc.)• Fax and e-mail address, if

available• Arrival and departure dates• Preferred hotels• Type of hotel room pre-

ferred (single, double, etc.)• Special preferences (smok-

ing, special needs, etc.)• Credit card information (for

hotel deposit)

Mail ExpoExchange/RSNA 2003108 Wilmot Rd., Ste. 400Deerfield, IL 60015-0823

Keep a copy of your completed registration form for your records.

NEWRSNA has added Hostelling Interna-tional – Chicago to its block of hotels.More information will be available inthe May issue of RSNA News.

November 30–December 5McCormick Place, Chicago

Registration FeesBY 10/31 ONSITE

$0 $100 RSNA Member, AAPM Member$0 $0 Member Presenter$0 $0 RSNA Member-in-Training and RSNA Student Member$0 $0 Non-Member Refresher Course Instructor, Paper Presenter,

Poster Presenter, Education or Electronic (infoRAD) Demonstrator$110 $210 Non-Member Resident/Trainee$110 $210 Radiology Support Personnel$520 $620 Non-member Radiologist, Physicist or Physician$520 $620 Hospital Executive, Research and Development Personnel,

Medical Service Organization, Healthcare Consultant, Industry Personnel

$300 $300 One-day registration to view the Technical Exhibits area.

For more information about registration at RSNA 2003, visit www.rsna.org, call (630) 571-7862 or e-mail reginfo@rsna.org.

Advance registration for RSNA 2003 opens April 28 for members of RSNAand AAPM. General registration opens May 27. Once you download theinformation from RSNA Link (www.rsna.org) or have it faxed to you, there arefour easy ways to complete the registration process:

Advance Registration and Housing Begins April 28

23R S N A N E W SR S N A N E W S . O R G

MEETINGWATCH:RSNA2003

2003 Preliminary Program Grid

SATURDAY11/29

FRIDAY12/5

THURSDAY12/4

WEDNESDAY12/3

TUESDAY12/2

MONDAY12/1

SUNDAY11/30

8:30 a.m.

9:00

9:30

10:00

10:30

11:00

11:30

12:00 p.m.

12:30

1:00

1:30

2:00

2:30

3:00

3:30

4:00

4:30

5:00

5:30

6:00

OpeningSession /President’sAddress8:30-10:15

EffectiveInvestmentStrategies*8:30-11:30

RefresherCourses 8:30-10:00

NeuroCase-BasedReview 8:30-10:00

RefresherCourses 8:30-10:00

IV Case-BasedReview8:30-10:00

EssentialsCourse8:30-10:00

EssentialsCourse10:30-12:00

EssentialsCourse10:30-12:00

ScientificSessions 10:30-12:00

ScientificSessions 10:30-12:00

AAPM/RSNAPhysicsTutorial forResidents12:00- 2:00

LunchBreak11:30-1:00

EffectiveInvestmentStrategies,cont.*1:00-4:00

Lunch,PosterSession, &VisitExhibits12:15-2:00

Lunch, Poster Session,& Visit Exhibits12:00-1:30

Lunch, Poster Session,& Visit Exhibits12:00-1:30

Lunch12:00-1:00

EssentialsCourse1:00-2:30

EssentialsCourse1:00-2:30

PlenarySession(RSNA/AAPM Sym-posium)**1:30-2:45

PlenarySession(AnnualOration inRadiationOncology)**1:30-2:45

Lunch12:00-1:00

Lunch, Poster Session,& Visit Exhibits12:00-1:30

Lunch,PosterSession, &VisitExhibits12:00-1:30

ImagingSymposium12:45-3:15

Lunch &VisitEducationExhibits12:00-12:45

RefresherCourses2:00-3:30

ScientificSessions3:00-4:00

ImageInterpreta-tion Panel4:00-5:45 Focus

Sessions 4:30-6:00

NeuroCase-BasedReview 3:30-5:45

IV Case-BasedReview3:30-6:00

Peds Case-BasedReview3:30-5:00

RefresherCourses 4:30-6:00

Oncodiag-nosis Paneland FocusSessions 4:30-6:00

ScientificSessions3:00-4:00

EssentialsCourse2:45-4:15

EssentialsCourse2:45-4:15

RefresherCourses 4:30-6:00

ScientificSessions3:00-4:00

FocusSessions3:00-4:00

PlenarySession(NewHorizons)**1:30-2:45

NeuroCase-BasedReview 1:30-3:00

IV Case-BasedReview1:30-3:00

Peds Case-BasedReview1:30-3:00

PlenarySession(AnnualOration inDiagnosticRadiology)**1:30-2:45

AAPM/RSNAPhysicsTutorial onEquipmentSelection2:15-5:15

RefresherCourses 8:30-10:00

Peds Case-BasedReview8:30-10:00

EssentialsCourse8:30-10:00

RefresherCourses 8:30-10:00

RefresherCourses 8:30-10:00

ScientificSessions10:45-12:15

ScientificSessions /AssociatedSciencesSymposium10:30-12:00

ScientificSessions /AssociatedSciencesSymposium10:30-12:00

ScientificSessions /AssociatedSciencesSymposium10:30-12:00

NeuroCase-BasedReview 10:30-12:00

IV Case-BasedReview10:30-12:00

Peds Case-BasedReview10:30-12:00

Two important changes in the program grid this year are a longer lunch period and the addition of the case-based reviewcourses. More information on these and other important enhancements will be included in the May issue of RSNA News.

*A registration fee is charged for this program. ** Awards/Ceremonies to begin at opening of Plenary Session (1:30-1:45)

24 R S N A N E W S A P R I L 2 0 0 3

Technical Exhibit HoursSun., Nov. 30–Wed., Dec. 3 10:00 a.m.–5:00 p.m.

Thurs., Dec. 4 10:00 a.m.–2:00 p.m.

EXHIBITORNEWS:RSNA2003

RSNA 2003 Exhibitor News

Exhibitor ProspectusThe RSNA 2003 Exhibitor Prospec-tus was mailed in late March. Toachieve maximum available spaceand assignment points, send yourcompleted application to RSNAHeadquarters as soon as possible.The first-round space assignmentdeadline is May 5, 2003.

Important Exhibitor Dates for RSNA 2003May 5 First-round space assignment

deadline

June 24 Exhibitor Planning/Booth Assign-ment Meeting

July 3 Technical Exhibitor Service Kit mails

Oct. 31 Exhibitor Badge deadline

Nov. 30– RSNA 89th Scientific AssemblyDec. 5 and Annual MeetingFor more information, contact RSNA Technical Exhibits at (630) 571-7851 or e-mail:

exhibits@rsna.org. For up-to-date information about technical exhibits at RSNA 2003,go to www.rsna.org/rsna/te/index.html.

June Exhibitor PlanningMeetingBooth assignments will be releasedJune 24 at the Exhibitor PlanningMeeting and Luncheon. Allexhibitors for RSNA 2003 are invit-ed to attend at Rosewood Restau-rant and Banquets near Chicago’sO’Hare International Airport.

Advertising at RSNA 2003Many opportunities exist for promoting your exhibit at RSNA 2003—theworld’s largest annual medical meeting. For more information, seewww.rsna.org/advertising/index.html or contact: Jim Drew Judy KapicakDirector of Advertising Advertising Manager(630) 571-7819 (630) 571-7818jdrew@rsna.org jkapicak@rsna.org

NEW

Changes for Exhibitors at RSNA 2003Exhibitors should be aware of a few important changes for RSNA 2003.Industry feedback played a role in some of the changes, while the currentbusiness climate played a role in other changes. All changes are included inthe Exhibitor Prospectus.

Exhibit HoursHours of operation have been modi-fied for the RSNA 2003 TechnicalExhibition. Instead of the traditionalclosing at 6 p.m. Sunday throughWednesday, the technical exhibitionwill close at 5 p.m. Hours will remain10 a.m. to 2 p.m. on Thursday.

Setback RuleThe setback requirement for freeformexhibit display components has beenreduced by one foot. Exhibits of1,400 square feet or less will beallowed a one-foot setback. Exhibitsof 1,500 square feet and over will beallowed a three-foot setback.

Use of GuidewiresExhibit structures can no longer besupported from the overhead steelstructure of the building without priorapproval. Use of guidewires must besubmitted with exhibitor floor plansfor review and approval.

HousingExhibitors will find it easier tosecure housing online this year. Thisincludes securing individual andblock housing. The allotment hasincreased to four rooms per 100square feet. Non-refundable blockhousing is no longer available.

The RSNA 2002 Technical Exhibition repre-sented 657 companies and medical associa-tions from around the world.

NEW

25R S N A N E W SR S N A N E W S . O R G

www.rsna.org

RSNA:ONTHEWEB

RSNA Link www.rsna.orgRadiology Onlineradiology.rsnajnls.orgRadiology Manuscript Centralradiology.manuscriptcentral.com

RadioGraphics Onlineradiographics.rsnajnls.orgRSNA Virtual Journal Clubvjc.rsna.orgEducation Portalwww.rsna.org/education/etoc.html

CME Credit Repositorywww.rsna.org/cmeRSNA Index to Imaging Literaturersnaindex.rsnajnls.org

NEW!RSNA Career Connectionscareers.rsna.org

RadiologyInfo™

RSNA-ACR public informa-tion Web sitewww.radiologyinfo.orgRSNA Online Products and Serviceswww.rsna.org/memberservices

RSNA Research & Education FoundationMake a Donationwww.rsna.org/research/foundation/donation

ec o n n e c t i o n s Your online links to RSNA

RSNA News Available in PDF Back issues of RSNA News arenow available in portable docu-ment format (PDF). The issues,dating back to June 2002, areavailable at www.rsna.org/publi-cations/rsnanews/archive/. Whenthe current issue is posted eachmonth, readers may choose toview the entire issue as a PDF orview each individual section as aWeb page.

Online Registration for RSNA CoursesRSNA will sponsor one spring and onesummer course this year. The springcourse is “PowerRAD 2003: PersonalDigital Image Management and Presen-tation,” which will be held on Saturday,May 31, at RSNA headquarters in OakBrook, Ill. The summer course is “Strate-

gies for Running a Successful RadiologyPractice,” which will be held July 11–13at The Lodge in Oak Brook.

Course objectives are available onpage 3. Online registration is now openat www.rsna.org/education/shortcourses/.

New Procedures added to RadiologyInfo™

RadiologyInfo™ (www.RadiologyInfo.org), the patienteducation Web site co-sponsored by RSNA and ACR,continues to expand. Two interventional procedureswere recently added. Information on uterine fibroidembolization is in the Women’s subsection of Inter-ventional Radiology. Radiofrequency ablation of livertumors is in a new Abdominal subsection.

Cryosurgery and vertebroplasty will added soon.

Membership Applicants Listed OnlineThe names of candidates for RSNA membership are now listed in the “Who’s Who”subsection of RSNA Link (www.rsna.org/about/whoswho/candidates.html). Societymembers are asked to review the names and follow the directions provided if theyhave a question concerning the eligibility of an applicant.

A new list of membership candidates will be posted each month.

Stats for RSNA 2002A two-page recap of RSNA 2002(www.rsna. org/rsna/2002recap.pdf) is posted in the annual meet-ing section under “ProfessionalRegistration” and “TechnicalExhibitors.”

The recap includes statisticson technical exhibits, scientificsessions, refresher courses andfinal registration figures.

Register Now for RSNA 2003Advance registration for RSNA 2003 opens April 28 forRSNA and AAPM members. Within the next few days, youwill receive a flyer explaining how to access the registrationsystem using your Internet browser through RSNA Link orby fax-on-demand service. See page 22 for more detailedinstructions.

Members are encouraged to register early to receive hotellodging of their choice. General registration opens May 27.

Medical Meetings May – June 2003

CALENDAR

MAY 4–9American Roentgen Ray Society (ARRS), 103rd Annual Meeting, San Diego Convention Center, San Diego • www.arrs.org/meeting/

MAY 7–10Society for Pediatric Radiology (SPR), Annual Meeting, Fairmont Hotel, San Francisco • www.pedrad.org

MAY 10Molecular Imaging, ASTRO/ACR Symposium, WashingtonHilton, Washington, D.C. • www.astro.org

MAY 10–13Australian and New Zealand Society of Nuclear Medicine(ANZSNM), 33rd Annual Scientific Meeting, Sheraton on thePark, Sydney, Australia • www.anzsnm.org.au

MAY 10–15ACR Annual Meeting & Chapter Leadership Conference, Washington Hilton, Washington, D.C. • (703) 716-7545

MAY 10–15American College of Medical Physics (ACMP), Annual Meeting, Sagamore Inn, Lake George, N.Y. • www.acmp.org

MAY 10–16International Society for Magnetic Resonance in Medicine(ISMRM), 11th Scientific Meeting and Exhibition, MetroToronto Convention Center, Toronto, Ontario • www.ismrm.org/03/

MAY 11–18Radiology in Italy, Medical College of Wisconsin & the Universities of Brescia and Parma, Parma and Stresa, Italy • www.radiologyintl.com

MAY 18–21Radiology Business Management Association (RBMA), Radiol-ogy Summit, Hyatt Regency San Antonio • www.rbma.org

MAY 31PowerRAD 2003: Digital Image Management and Presenta-tion, RSNA Headquarters, Oak Brook, Ill. • (630) 368-3747or ed-ctr@rsna.org

JUNE 1–410th Congress of the World Federation for Ultrasound in Medi-cine and Biology (WFUMB), Montreal Convention Center,Quebec • (800) 638-5352 or www.aium.org

JUNE 1–4American Board of Radiology (ABR), Oral Exams for Diagnos-tic Radiology, Radiologic Physics, Radiation Oncology,Louisville, Ky. • www.theabr.org

JUNE 2–6European Society of Pediatric Radiology (ESPR), Annual Meet-ing, Magazzini del Cotone-Porto Antico, Genoa, Italy • www.espr2003genoa.org

JUNE 6–7Advanced Course in Grant Writing, RSNA Department ofResearch, RSNA Headquarters, Oak Brook, Ill. • (630) 368-3758 or dor@rsna.org

JUNE 7–10Society for Computer Applications in Radiology (SCAR), 20th Symposium for Computer Applications in Radiology,Hynes Convention Center, Boston Sheraton Hotel, Boston • (703) 757-0054

JUNE 14–16Canadian Association of Medical Radiation Technologists(CAMRT), Annual General Conference, Winnipeg, Manitoba • www.camrt.ca

JUNE 15–17UK Radiological Congress, Birmingham, UK • www.ukrc.org.uk

JUNE 15–19American Medical Association (AMA), Annual Meeting, Hyatt Regency, Chicago • (312) 464-5000

JUNE 17–20European Society of Gastrointestinal and Abdominal Radiology(ESGAR), 14th Annual Meeting and Postgraduate Course,Budapest, Hungary • www.esgar.org

JUNE 21-25Society of Nuclear Medicine (SNM), 50th Annual Meeting,Ernest N. Morial Convention Center, New Orleans • www.snm.org

JUNE 23–24BECON 2003 Symposium on Catalyzing Team Science, Natcher Conference Center, National Institutes of Health,Bethesda, Md. • www.becon1.nih.gov/symposium2003.htm

JUNE 25–28Computer Assisted Radiology and Surgery (CARS), 17th Inter-national Congress and Exhibition, London QEII ConferenceCentre, London • www.cars-int.de

JUNE 26–28National Congress of the Swiss Society of Radiology (SSR),Lucerne • www.sgr-ssr.ch/

JULY 11-13Strategies for Running a Successful Radiology Practice, RSNA Headquarters, Oak Brook, Ill. • (630) 368-3747 orwww.rsna.org/education/shortcourses

NOVEMBER 30–DECEMBER 5RSNA 2003, 89th Scientific Assembly and Annual Meeting,McCormick Place, Chicago • www.rsna.org