November4th8:00am–5:00pmNovember5th9:30am–12:00pmUniversityofCalifornia,SanFrancisco

MissionBayCampusGenentechHall,ByersAuditorium17004thStreet,SanFranciscoCA

QuickGuide

Schedule.................................................................................................................................2

PresentationDetails...............................................................................................................3

Registration/Check-in.............................................................................................................3

Hotel......................................................................................................................................3

GettingtoBIOMOD................................................................................................................4

TransportationOptions..........................................................................................................5

OnceatUCSFCampus–GettingtoGenentechHall.................................................................5

BuildingSecurity.....................................................................................................................6

Meals.....................................................................................................................................6

Judging...................................................................................................................................6

AwardCategories...................................................................................................................8

SanFrancisco-PlacestoEat...................................................................................................9

OrganizerContactInfo............................................................................................................9

2017BIOMODSponsors.......................................................................................................10

BIOMODHistory...................................................................................................................11

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ScheduleFriday,November3rd,20172:00PMto6:30PM TeamRegistrationattheUniversityofCalifornia 60016thStreet,SanFrancisco,CA94058–GenentechHall CheckinatSecurityonthe1stfloor.PresentyourvalidIDforavisitor’sbadge

ProceedtotheDouglasLabonthe4thFloor–RoomS472PickupyourBIOMODIDbadgeandt-shirt!PracticeyourpresentationinaUCSFConferenceroom(bypriorarrangement)

Saturday,November4th,2017

07:00–07:15AM MakeyourwaytoUCSFMissionBay—GenentechHall.07:15–08:00 Breakfastwillbeavailabletoallregisteredteams. 08:00–08:15 Welcome —OpeningRemarks08:15–08:30 Kansai —DNARandomizer08:30–08:45 Oxford —RibOxSwitch08:45–09:00 YOKABIO —TheTransporter09:00–09:15 NTU-Taiwan —NanoMuscle09:15–09:30 CrystallineEntity —3DMolecularPegboard09:30–09:45 Nano-JLU —Nanoreactor09:45–10:00 MultiBrane —Clearingmicropollutants10:00–10:30 CoffeeBreak10:30–10:45 Biodesigners —Catechinencapsulation10:45–11:00 Season —LinkedDNAnetworks11:00–11:15 Sendai —Self-healingDNA‘n’GEL11:15–11:30 teamHANDAI —DNAUFOCatcher11:30–11:45 UCSanDNAgo —HSV-loadedOrigami11:45–12:00 CapsidConstructors —ArtificialHIVcapsid12:00–12:15PM GroupPhoto12:15–13:30 Lunch13:30–13:45 CGUnion —Biomarkerdetection13:45–14:00 UsydUfold —FortuneCookie:viralbiosensor14:00–14:15 ToeholdCongaNanny —ClawCatchingNorovirus14:15–14:30 MolecularJedis —Lightzaber:sensingmiRNA-14114:30–14:45 UBerCooleculars —LungcancermiRNAɸ29RCAssay14:45–15:00 NCKU-Taiwan —CompetingwithHuR15:00–15:30 RefreshmentBreak15:30–15:45 OhioMOD —TherapeuticStabilityofOrigami15:45–16:00 BONMED —PrecisionSmurf1inhibition16:00–16:15 HUST-China —StarvingcancercellswithSIREN16:15–16:30 Wrapup16:30–17:00 Judgessubmitscores

Sunday,November5,2017Reminder:DaylightSavingTimeendsintheUnitedStatesonSunday,November5at2:00AM.Pleaseremembertosetyourclocksbackby1hourbeforegoingtosleeponSaturdaynight.

08:00–08:15AM MakeyourwaytoUCSF,GenentechHall.08:15–09:30 Breakfastwillbeavailabletoallregisteredteams.09:30–11:00 Awards&ClosingCeremony 11:00–12:00PM Socialize+Boxlunch(Untilcheckoutofhotelat12)12:00–13:30 BoardofDirectorsMeeting(Shokat,Rothemund,Murata,Douglas)

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PresentationDetailsAllteampresentationswilltakeplaceinByersAuditoriumintheGenentechHallbuildingontheUniversityofCalifornia,SanFranciscoMissionBayCampus.TheTOTALtimeallottedtoeachteamis15minutes.Thisincludeslaptopsetup(1min),presentslides(10min),audiencequestions(~3min),andexitingthestage+buffertime(1min).Thetimelimitswillbestrictlyenforced,sorehearsinginadvanceisstronglyrecommendedtoavoidbeingcutoff.Theroomisequippedwithaprojectorandscreen.Pleaseremembertobringlaserpointers,converters,adapters,cables,etc.,asthesewillnotbeprovidedbyBIOMOD.Ifyouhaven’talreadydoneso,youmaysignupforapracticesessionhere:http://bit.ly/2yDlWdN.Practicesessionsarestrictlylimitedto30minutes.Thanksinadvanceforarrivingontime,andfinishinginthetimeallotted.

Registration/Check-inAllteamsarerequiredtocheck-inforBIOMODonFriday,November4thbetweenthehoursof13:30–18:30.RegistrationwillbelocatedintheDouglasLabattheUniversityofCalifornia,SanFranciscoMissionBayCampusinGenentechHall.Eachindividualwillberequiredtocheck-inwithvalidIDattheUCSFSecurityDeskonthe1stfloorofGenentechHall.Onceyoureceiveavisitor’sbadge,youmayproceedtothe4thFloorandofficesuiteS472.TogettotheDouglasLabofficesuite,taketheelevatordirectlybehindthesecuritydesktothe4thfloor.Whenyougetofftheelevatorwalktothecarpetedhallwayandproceedtotheright.Turnleftintothe2ndcorridormarked“S401-484”.Walkstraightdownthiscorridorandbeartowardtheright,enteringthecommonareamarkedS472.Proceedthroughthecommonarea,throughthedoubleglassdoorsandintotheS472officesuite.Allteammembersshouldarrivetogetherasagroup.Atregistrationeachteamwillreceive:

• BIOMODID/Securitybadges(whichmustbewornatalltimeswhileontheUCSFcampus)• Lyftvouchercodeworth$50fortransportationtoandfromtheUCSFcampus• Participationcertificates*• BIOMODt-shirts.

*IfthereareteammemberswhoarenotabletoattendtheJamboree,butwhowouldlikeaparticipationcertificate,pleaseemailRebecca(Rebecca@biomod.net)inadvancewiththeirnames.

HotelTheofficialhotelofBIOMOD2017isHotelZelosindowntownSanFrancisco.Address: 12FourthStreet SanFrancisco,CA94103 Check-intimeisat3:00PM Telephone:(415)348-1111 Check-outtimeisat12:00PM

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RoomCreditsParticipantsstayingattheofficialBIOMODhotelareeligiblefora$500perteamroomcredit.Toreceivethiscredit,youMUSThave1)bookedyourroomthroughthelinkprovidedontheregistrationsystemand2)providedyourhotelconfirmationnumber(s)ontheappropriatesectionoftheregistrationsystem.Therearenoexceptionstothis.IfyoudidnotreportyourconfirmationnumbersbeforetheSeptember25thdeadline,youwillnotbeeligiblefortheroomcredit.Thecreditwillbesplitequallyamongteamsdependingonhowmanyroomsyoubookedandwillbeappliedtoyourfinalbillatcheck-out.HotelZelosMap:http://bit.ly/2w6ZXY8

GettingtoBIOMODLocation: UniversityofCalifornia,SanFrancisco MissionBayCampus GenentechHall,ByersAuditoriumAddress: Near17004thStreet,SanFranciscoCA94158. (DirecttaxiorLyfttothisaddress,andthenwalkwestpastByersHalltoGenentechHall)

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TransportationOptionsFrom:HotelZelos(12FourthStreet,SanFrancisco,CA94103)To:theUCSFMissionBayCampus(17004thStreet,SanFrancisco,CA94158)

Lyft$8–$11(15min)FromanywhereinSanFranciscoandsurroundingareas.DownloadtheLyftapponyoursmartphoneandsetupanaccount.Useyourphonetoarrangequickcarservice.Thisappusesyoursmartphone’sGPStodetectyourlocationandconnectyouwiththeclosestavailabledriver.Youwillreceiveatextmessagewithaphotographofyourbackground-checkeddriverandtheircar,you’llbeabletotracktheirapproach,andgetatextmessagewhentheyarrive.Paymentcanbesplitamongpassengersandwillbesecurelychargedtothecreditcardonfile.Nocashwillchangehands.Usethestreetaddressof17004thStreet,SanFranciscoforeasiestaccesstoGenentechHall.LyftVouchersInanefforttofurtherhelpoffsetcostsforattendingBIOMOD,wearepleasedtoprovideeachteama$50vouchercodeforLyfttrips.TousethisvoucheryoumustdownloadtheLyftapponyoursmartphoneandsetupanaccount.Note:ifyouarenewLyftuser,youmayalsobeeligibleforotherpromotionalcreditsuponsettingupanewaccount.Visithttps://www.lyft.com/promo-coupon-code-free-ridesfordetails.Youmayusethevouchersforanytrippicking-upordropping-offwithin0.5milesoftheUCSFcampus.Taxi:$14–16(15min)UsethetaxistandattheHotelZelosandtakeataxitoUCSF.Usethestreetaddressof17004thStreet,SanFranciscoforeasiestaccesstoGenentechHall.

OnceatUCSFCampus–GettingtoGenentechHallOnceyouarriveonCampusfromthetaxidropoffareaon4thstreet,walkwestalongCampusWay,pastByersHall,totheentranceofGenentechHallindicatedonthemap.NotethatCampusWayisasidewalkpaththatisjustnorthofGenentechHallandsouthof“KoretQuad”(treesandgrass).EnterthebuildingatmainGenentechHallentrancebetweenthecircularstonestepsandtheByersHallentrance.HereisaMapofUCSFMissionBayCampus:https://www.dropbox.com/s/579hj3w64twg445/UCSF_Mission_Bay_Map.pdf?dl=0

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BuildingSecurityTheGenentechHallbuildingatUCSFwillonlybeaccessiblethroughthemainGenentechHallentrance.YoumustbringIDforsecuritycheck-in,andyoumustwearyourBIOMODIDbadgeatalltimeswhileoncampus.

MealsSaturday: Breakfast,morningsnack,lunch,andafternoonrefreshmentswillbeprovided.Sunday: Breakfastandaboxlunchwillbeavailableforallattendees.Ifyouhaveanyfoodallergiesthatwerenotnotedonyourregistration,pleaseletusknowimmediately.

JudgingOuraimistomaintainanopenandfairprocessforevaluatingeachteam'sperformance.Teamswillbescoredbyjudgesusingapointsystem.Thejudgingprocesswillhavetwostages:onlinecontent(worthupto75points)andlivepresentation(worthupto25points).Onlinecontentscoring

• Maximumcombinedscoreforonlinecontentis75points(=50pointsforwiki+25pointsforinternetvideo)

• Scoreswillbedeterminedbyarange-votingsystem.• Five(5)judgeswillberandomlyassignedtoeachteam.• Judgeswillevaluateeachprojectaccordingtoarubric(seebelow)andassignapointvaluein

eachcategory.• Highestandlowestjudges'totalscoresareexcludedtoremoveoutliers.• Threeremainingjudges'scoreswilleachweightedby1/3andcombinedtodeterminethetotal

scoresforeachcategory.

Website(upto50points)ProjectIdea(20points)

• Relevance:Hastheteammadeastrongcasethattheirprojectideaisscientificallyand/ortechnologicallyinteresting?(5points)

• Specification:Aretheprojectgoalswell-defined?(i.e.Doestheteamexplicitlystatewhatcriterianeedtobemetinordertoconsidertheprojectasuccess?)(5points)

• Feasibility:Wastheproposedsolutionfeasible?(i.e.WasitreasonabletoexpectthatthesolutioncouldbeimplementedbyaBIOMODteaminonesummer?)(5points)

• Merit:Istheproposedsolutionagoodone?Isitparticularlyelegantorinnovative?(5points)

ProjectDocumentation(20points)• Clarity:Istheprojectdescriptionwell-writtenandeasytounderstand?Doesitincludethe

backgroundandmotivationoftheproject,methods,results,anddiscussion?Arethefigureseasytounderstand?(10points)

• Transparency:Arealloftherawexperimentaldataandsourcefileseasilyaccessible?Woulditbestraightforwardtoattempttoreproducetheteam'sresults?(5points)

• Layout:Istheteam'sprojectpagearrangedinaclearandlogicalfashion?(5points)

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ProjectExecution(10points)

• Execution:Didtheteamaccomplishwhattheysetouttodo?(10points)

YouTubevideo(upto25points)• Overallimpact:Wasthevideointeresting?Didyouwanttowatchmorethanonce?(10points)• Clarity:Wastheprojectdescribedinasimpleandclearmannerthatcouldbeeasilyunderstood

byawideaudience?(10points)• Production:Wasthesoundandvideohighquality?Weretheimagesfocusedandscaled

properly?(5points)

Presentationscoring(upto25points)• Content:Weretheslidesclearandeasytounderstand?Didtheprojectnarrativehavealogical

flow,withclearlystatedgoalsandresults?(10points)• Delivery:Didthespeaker(s)giveawell-rehearsed,well-pacedpresentation?Didthespeaker(s)

engagewiththeaudienceandmaintaingoodeyecontact?(10points)• Impact:Wasthepresentationinteresting?fun?clever?memorable?(5points)

Judges• JudgeswereselectedfromapoolofBIOMODfacultymentorsandoutsideexperts.• Mentorswillnotevaluatetheirownteam.• The2017BIOMODJamboreeJudgesare:

AliceWilliamsonCarlosCastroChenxiangLin

Ching-PingTsengChristopherSnowEbbeAndersenEdwardChernFrancescoRicci

GriselFierrosRomeroHans-GeorgBraun

HenryHessHuangChao

Jeng-ShiungJanJorgenKjems

JosephSchaefferKalaumariMayoralPeña

KeiFujiwaraKeisukeMorishima

KenKomiya

KishioOnoLIANGCHAOManishGupta

MasahiroTakinouePatrickYue

PhilipLukemanPhilipTinnefeldRobertWangSabaNojoumiSatoshiMurataShelleyWickhamShinichiroNomuraShizhenWangShogoHamadaShuwenGuanSzechengJ.Lo

TakashiNakakukiYonggangKeYu-FonChen

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AwardCategoriesThefollowingprizeswillbeawarded:TopPrizes

• Grandprize=1sthighesttotalcombinedpointsfromwiki+video+presentation• 1strunnerup=2ndhighesttotalcombinedpointsfromwiki+video+presentation• 2ndrunnerup=3rdhighesttotalcombinedpointsfromwiki+video+presentation

Categoryawards

• BestWebsite=1stplace,2ndplace,3rdplace• BestYouTubeVideo=1stplace,2ndplace,3rdplace• BestPresentation=1stplace,2ndplace,3rdplace• AudienceFavorite=1stplace,2ndplace,3rdplace

Projectawards

• Bronze:Teamsatisfiedallminimumrequirementsforjudging(i.e.SubmittedacompleteProjectwikianduploadedaYouTubevideo)

• Silver:SatisfiedcriteriaforBronze,plusatleastonedevice(partofthesystem)intheteam'sdesignisworkedasexpected.

• Gold:SatisfiedcriteriaforSilver,andoverallpointscorefromWiki+YouTube+Jamboreepresentationareintop50%ofallteams.

SpecialAwards• The7thAnnualMolecularRoboticsAward(byMOLBOT,Japan)• AudienceChoiceAward–BestProject• BestTeamT-shirtAward• BestUseofGameEngine

SurveyWeareinterestedinyourfeedbackforhowtoimproveBIOMOD,especiallyfromstudents.Pleasefilloutoursurveyhere:http://bit.ly/biomod17survey

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SanFrancisco-PlacestoEatDowntown(neartheHotelZelos)BlueBottleCoffee–(66MintPlaza,betweenJessieandMissionStreet).Trendycafechainofferingupscalecoffeedrinks&pastries.Hoursare6:30AMto7:30PM,daily.WestfieldCenter–(865MarketStreet).Thislarge,upscaleshoppingcenteroffersmanyinternationaldiningoptionsinthelowerlevelfoodcourt,includingThai,Japanese,Chinese,Mexican,Korean,ItalianandAmericanfare.Hoursare10AMto8:30PMMonday–Saturday;10AMto7PMonSundays.Metreon–(135FourthStreet@MissionStreet).Largeshoppingcenterwithmanyrestaurantandentertainmentoptions,includingMexican,Burgers,Filipino,Thai,Vietnamese,Italian,aswellasicecream,dessertandcoffeeshops.Hoursare10:30AMto9:30PMdaily.Mel’sDrive-In–(801MissionStreet@4thStreet).Old-fashioned,50sstyleAmericandinerfoodservedinaretrodrive-insettingfeaturingat-tablejukeboxes.Hoursare6AMto12AMdaily.PotreroHill(10–15minwalkfromUCSF)Sunflower(288ConnecticutStreetat18th)—ExcellentVietnamesefood$8–12.Pera(145718thSt)–Mediterraneantapas,goodfood.$15–25.LiveSushi(200117thStreetatKansas)—Sushi$11–30.Dogpatch(10–15minwalkfromUCSF)Serpentine(24953rdStreet)—NewAmerican.Goodburgers.$12–30.MoshiMoshi(20923rdStreet,nearthecornerof18th)—Sushi/Japanese.StandardAmericanJapaneserestaurantfare.$15–20.

Mission(10mintaxiorLyftfromUCSF,orBARTfromdowntown@16thand24thStreet)TaqueriaVallarta(303324thStreet,nearHarrison)—Excellentstreettacos.$5–10.TaqueriasElFarolito(2779MissionStreet@24th)—Greatburritos.$8–12.LimónRotisserie(1001SouthVanNessor524Valencia)—AmazingPeruvianfood.$12–20.Yamo(340618thStreet@Mission)—Burmesefood.Holeinthewall,usuallyaline.$8–10.NamuGaji(499DoloresStreet@18th)—Koreanfusion.NexttoBi-RiteIceCream!$14–20.LaTaqueria(2889MissionStreet,near25th)–“BestBurritoinAmerica”Greattacos;Crowded.$10–15.…MANYothergreatoptionsonMissionStreet,ValenciaStreet,and24thStreet.

OrganizerContactInfoRebeccaWheelercell:+1-650-438-2557email:rebecca@biomod.netShawnDouglascell:+1-617-935-7047email:shawn@biomod.net

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2017BIOMODSponsors

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Over1200students,mentors,andjudgeshaveparticipatedsince2011.

BIOMODHistoryTheBIOMODcompetitionwasbegunatHarvardUniversitybytheWyssInstituteforBiologicallyInspiredEngineering,whichconductedthecompetitionduringtheyears2011to2015.Themissionofthecompetitionwastoinspireagenerationofstudentstolearntoengineerbiomoleculesatthenanometerscale.In2016,BIOMODFoundationassumedmanagementofthecompetition.From2011–2015,theleadeventscoordinatorattheWyssInstitutewasJermaineReid,whowasinstrumentalinmakingBIOMODasuccess.JermaineworkedcloselywithMaryTolikas(DirectorofOperations),alongwithAlisonReggio,MaryWozniak,andCaitlinWells.TheBIOMODwebsiteandCompetitionManagementSoftwarewereoriginallydevelopedbyKristianSt.GabrielandByronHinebaugh.TheBIOMODFoundationiscurrentlyrunbyitsboardofdirectors:ShawnDouglas(UCSF),PaulRothemund(Caltech),KevanShokat(UCSF),MaryTolikas(WyssInsitute),andSatoshiMurata(TohokuUniversity),andsupportedbyRebeccaWheeler(leadorganizer),RobertPierce(legal),andRachelDulay(accounting).Thisyear,2017,marksthesecondtimethatBIOMODwillbehostedinCalifornia.