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MD/DO Learner got 15 of 15 possible points on the Biology, Medications, and Surgical Options Post-Test. Total score: 100 % Question Results Question #1 of 15: Multiple choice question Mr. Gregory wants a weight-loss surgery that is likely to help him lose at least 50% of his excess weight. He is willing to make the required diet and exercise changes and obtain behavioral support. Which of the following gastric surgeries is unlikely to help him lose that much weight? Laparoscopic Adjustable Gastric Band Vagal Blocking Therapy Vertical (Sleeve) Gastrectomy Roux-En-Y Gastric Bypass Mr. Gregory is not likely to lose 50% of his excess weight with any of the above surgeries. Response: Laparoscopic Adjustable Gastric Band Vagal Blocking Therapy Feedback: Correct! Vertical (Sleeve) Gastrectomy Roux-En-Y Gastric Bypass Mr. Gregory is not likely to lose 50% of his excess weight with any of the above surgeries.

Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

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Page 1: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

MD/DO Learner got 15 of 15 possible points on the Biology, Medications, and Surgical Options Post-Test.Total score: 100 %

Question ResultsQuestion #1 of 15: Multiple choice question

Mr. Gregory wants a weight-loss surgery that is likely to help him lose at least 50% of his excess weight. He is willing to make the required diet and exercise changes and obtain behavioral support. Which of the following gastric surgeries is unlikely to help him lose that much weight?

Laparoscopic Adjustable Gastric Band

Vagal Blocking Therapy

Vertical (Sleeve) Gastrectomy

Roux-En-Y Gastric Bypass

Mr. Gregory is not likely to lose 50% of his excess weight with any of the above surgeries.

Response:

Laparoscopic Adjustable Gastric Band

Vagal Blocking Therapy

Feedback:

Correct!

Vertical (Sleeve) Gastrectomy

Roux-En-Y Gastric Bypass

Mr. Gregory is not likely to lose 50% of his excess weight with any of the above surgeries.

Page 2: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Question #2 of 15: Multiple choice question

After weight loss surgery, which of the following diet approaches are recommended for optimal weight loss with fewest side effects?

A high-carb diet

Limiting soda intake to no more than 2 per day

Low fat diet taken in 3 meals per day

Small, protein-based meals

Response:

A high-carb diet

Limiting soda intake to no more than 2 per day

Low fat diet taken in 3 meals per day

Small, protein-based meals

Feedback:

Correct!

Question #3 of 15: Multiple choice question

High fat/high sugar foods resemble addictive substances by (choose best answer):

Decreasing serotonin levels

Inhibiting neurons in the nucleus accumbens

Page 3: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Increasing dopamine levels

Decreasing mood

All of the above

Response:

Decreasing serotonin levels

Inhibiting neurons in the nucleus accumbens

Increasing dopamine levels

Feedback:

Correct!

Decreasing mood

All of the above

Question #4 of 15: Multiple choice question

Which of the following medications can produce weight loss but is NOT FDA-approved for weight-loss treatment in non-diabetics?

Bupropion/Naltrexone

Liraglutide

Metformin

Page 4: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Nortriptyline

Response:

Bupropion/Naltrexone

Liraglutide

Metformin

Feedback:

Correct!

Nortriptyline

Question #5 of 15: Multiple choice question

Mr. Murphy is obese and is taking a beta blocker for hypertension. Which provider explanation most accurately and appropriately discusses this with him?

"Your blood pressure medication causes weight gain, but you need it to control your bloodpressure. So, we need to add a weight-loss medication."

"Your blood pressure is well-controlled by your antihypertensive but your medication maycontribute to weight gain. Other medications might control your blood pressure and notcause weight gain. Would you be open to trying one of them?"

"Your anti-hypertensive medication is a good choice because it controls your blood pressurewell and helps with weight loss at the same time."

"Your anti-hypertensive medication is a good choice because it does not cause you to gainweight."

Page 5: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Response:

"Your blood pressure medication causes weight gain, but you need it to control yourblood pressure. So, we need to add a weight-loss medication."

"Your blood pressure is well-controlled by your antihypertensive but your medicationmay contribute to weight gain. Other medications might control your blood pressureand not cause weight gain. Would you be open to trying one of them?"

Feedback:

Correct!

"Your anti-hypertensive medication is a good choice because it controls your bloodpressure well and helps with weight loss at the same time."

"Your anti-hypertensive medication is a good choice because it does not cause you togain weight."

Question #6 of 15: Multiple choice question

Ms. Jessica Lincoln meets criteria for weight-loss medication and has been diagnosed with mild depression. Which of the following weight-loss medications also could help with depression?

Liraglutide

Bupropion/Naltrexone

Phentermine with Topiramate ER

Orlistat

Response:

Liraglutide

Bupropion/Naltrexone

Page 6: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Feedback:

Correct!

Phentermine with Topiramate ER

Orlistat

Question #7 of 15: Multiple choice question

Edith Worthington is obese with obstructive cholestasis and mild malabsorption. She agreed to start weight-loss pharmacotherapy. Which of the following medications is a POOR FIT for her:

Liraglutide

Phentermine with Topiramate ER

Lorcaserin

Orlistat

Response:

Liraglutide

Phentermine with Topiramate ER

Lorcaserin

Orlistat

Feedback:

Correct!

Page 7: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Question #8 of 15: Multiple choice question

Ruth Petty was prescribed lorcaserin for weight loss. All of the following are topics that should be discussed with her regarding this treatment EXCEPT:

Likely effectiveness of medication

Possible weight regain once medication is stopped

Need for concurrent lifestyle changes and counselor support

Need for a daily injection

Response:

Likely effectiveness of medication

Possible weight regain once medication is stopped

Need for concurrent lifestyle changes and counselor support

Need for a daily injection

Feedback:

Correct!

Question #9 of 15: Multiple choice question

Which of the following commonly occurs following significant weight loss?

Decrease in circulating leptin levels

Increase in resting energy expenditure

Page 8: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Decrease in circulating ghrelin levels

Stimulation of anorexigenic pathways

All of the above

Response:

Decrease in circulating leptin levels

Feedback:

Correct!

Increase in resting energy expenditure

Decrease in circulating ghrelin levels

Stimulation of anorexigenic pathways

All of the above

Question #10 of 15: Multiple choice question

Ms. Lindsay complains of weight gain from taking Quetiapine (Seroquel®) for psychosis. Which of the following antipsychotic medications is likely to produce less weight gain or no weight gain?

Chlorpromazine (Thorazine®)

Ziprasidone (Geodon®)

Olanzipine (Zyprexa®)

Page 9: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Clozapine (Clozaril®)

Response:

Chlorpromazine (Thorazine®)

Ziprasidone (Geodon®)

Feedback:

Correct!

Olanzipine (Zyprexa®)

Clozapine (Clozaril®)

Question #11 of 15: Multiple choice question

Ms. Ellington is moderately obese and needs to be prescribed medication for type 2 diabetes. Which of the following medications being considered is most likely to cause weight gain?

Metformin

GLP-1 Analogs (e.g., exanatide, liraglutide)

Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitors (e.g., canagliflozin, dapagliflozin,empagliflozin)

Sulfonylureas (e.g. glipizide, glimepiride, glyburide)

Response:

Metformin

Page 10: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

GLP-1 Analogs (e.g., exanatide, liraglutide)

Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitors (e.g., canagliflozin, dapagliflozin,empagliflozin)

Sulfonylureas (e.g. glipizide, glimepiride, glyburide)

Feedback:

Correct!

Question #12 of 15: Multiple choice question

Question: Which patient best meets guidelines for weight-loss surgery consideration?

Mr. George, BMI 37, has no comorbidities but says he cannot lose weight on his own.

Ms. Rounds, BMI 35, has diabetes. She has tried diet and exercise with no success.

Ms. Paul, BMI 39, has no comorbidities and does not want to try pharmacotherapy.

Mr. Frank, BMI 31, has issues with impulse control. He sees surgery as his only option forweight loss.

Response:

Mr. George, BMI 37, has no comorbidities but says he cannot lose weight on his own.

Ms. Rounds, BMI 35, has diabetes. She has tried diet and exercise with no success.

Feedback:

Correct!

Page 11: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Ms. Paul, BMI 39, has no comorbidities and does not want to try pharmacotherapy.

Mr. Frank, BMI 31, has issues with impulse control. He sees surgery as his only optionfor weight loss.

Question #13 of 15: Multiple choice question

Ms. Boothe meets all criteria for weight-loss surgery. She prefers to have a surgery that can be reversed even if that means her overall weight loss will be less. Which type of surgery fits that criterion?

“Long Limb” Gastric Bypass

Roux-En-Y Gastric Bypass

Laparoscopic Adjustable Gastric Banding (LAGB)

Vertical (Sleeve) Gastrectomy

Response:

“Long Limb” Gastric Bypass

Roux-En-Y Gastric Bypass

Laparoscopic Adjustable Gastric Banding (LAGB)

Feedback:

Correct!

Vertical (Sleeve) Gastrectomy

Page 12: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Question #14 of 15: Multiple choice question

Which of the following patients is the best candidate for weight-loss pharmacotherapy?

Larry (BMI 26) has had minor success with dieting and exercise.

Walter (BMI 24) has had little success losing weight with diet and exercise.

Olive (BMI 29) has hypertension and dyslipidemia and has tried dieting and exercise to loseweight with no success.

Dina (BMI 30) is seeking pharmacotherapy as a substitution for diet and exercise.

Response:

Larry (BMI 26) has had minor success with dieting and exercise.

Walter (BMI 24) has had little success losing weight with diet and exercise.

Olive (BMI 29) has hypertension and dyslipidemia and has tried dieting and exercise tolose weight with no success.

Feedback:

Correct!

Dina (BMI 30) is seeking pharmacotherapy as a substitution for diet and exercise.

Question #15 of 15: Multiple choice question

Patient: Scott Rowe, age 35

Presentation: Mr. Rowe has a BMI of 29 kg/m2. He also has high cholesterol and hypertensionand takes 20 mg of fluoxetine (SSRI) daily, for depression. He has been unable to lose weight byany other method and indicates that he is interested in pharmacotherapy for weight loss.

Question: After determining that he is indeed eligible for such treatment, which medicationwould NOT be appropriate to prescribe Mr. Rowe?

Page 13: Question Results · Which of the following patients is the best candidate for weight-loss pharmacotherapy? Larry (BMI 26) has had minor success with dieting and exercise. Walter (BMI

Orlistat

Lorcaserin

Phentermine

Phentermine-Topiramate

Response:

Orlistat

Lorcaserin

Feedback:

Lorcaserin can interact with SSRIs; these medications should not be prescribedtogether.

Phentermine

Phentermine-Topiramate