Quentry for SRS Registry 3 · Quentry for SRS Registry can read treatment plans written by these applications as long as the loading criteria specifications in the user guide are

QUENTRY FOR SRS REGISTRYQUENTRY

QUENTRY.COMVersion 3.1

Software User GuideRevision 1.1Date of issue: 2019-11-12 (ISO 8601)Copyright 2019, Brainlab AG Germany. All rights reserved.

TABLE OF CONTENTS1 GENERAL INFORMATION.............................................................................................5

1.1 Contact Data ........................................................................................................................................5

1.2 Legal Information ...............................................................................................................................6

1.3 Symbols................................................................................................................................................8

1.4 Using the System ...............................................................................................................................9

1.5 Compatibility with Software ...........................................................................................................10

1.6 Training and Documentation ........................................................................................................12

1.7 Technical requirements...................................................................................................................13

1.8 Abbreviations ....................................................................................................................................14

2 PREPARATION AND DATA UPLOAD ...............................................................15

2.1 About SRS Registry .........................................................................................................................15

2.2 Data Requirements...........................................................................................................................17

2.3 Import Criteria ...................................................................................................................................19

2.4 Exporting Data from Treatment Planning Systems...................................................................20

2.5 Cranial Contouring Workflow ........................................................................................................21

3 USING QUENTRY FOR SRS REGISTRY........................................................25

3.1 Getting Started ..................................................................................................................................25

3.2 Tasks ...................................................................................................................................................26

3.3 Forms ..................................................................................................................................................29

3.4 Patients ...............................................................................................................................................36

3.5 Analytics.............................................................................................................................................40

3.6 Patient Follow-Up Report................................................................................................................44

3.7 User and Account Settings ............................................................................................................45

TABLE OF CONTENTS

Software User Guide Rev. 1.1 Quentry for SRS Registry Ver. 3.1 3

TABLE OF CONTENTS

4 Software User Guide Rev. 1.1 Quentry for SRS Registry Ver. 3.1

1 GENERAL INFORMATION1.1 Contact Data

Support

If you cannot find information you need in this guide, or if you have questions or problems, contactBrainlab support:[email protected]

Expected Service Life

Brainlab provides five years of service for software applications. During this period of time,software updates as well as field support are offered.

Feedback

Despite careful review, this user guide may contain errors. Please contact us [email protected] if you have improvement suggestions.

Manufacturer

Brainlab AGOlof-Palme-Str. 981829 MunichGermany

GENERAL INFORMATION


mailto://[email protected]

mailto:[email protected]

1.2 Legal Information

Copyright

This guide contains proprietary information protected by copyright. No part of this guide may bereproduced or translated without express written permission of Brainlab.

Brainlab Trademarks

• Brainlab® is a trademark of Brainlab AG.• Quentry® is a trademark of Brainlab AG.

Non-Brainlab Trademarks

• Microsoft®, Windows® and Internet Explorer® are registered trademarks of MicrosoftCorporation in the US and other countries.

Patent Information

This product may be covered by one or more patents or pending patent applications. For details,see: www.brainlab.com/patent.

Integrated Third-Party Software

This software is based in part on the following work:• The Independent JPEG Group.• The AWS SDK for .NET developed by Amazon.com, Inc.• The ClearCanvas SDK developed by ClearCanvas, Inc.• The Log4Net developed by the Apache Software Foundation.• The Microsoft .NET Framework SDK developed by Microsoft Corp.• The Microsoft .NET Framework (WCF) developed by Microsoft Corp.• The Microsoft DeepZoomTools developed by Microsoft Corp.• The Microsoft DirectX SDK (February 2010) developed by Microsoft Corp.• The Open DICOM developed by Albert Gnandt.• The SharpZipLib (.NET).

CE Label

The CE label indicates that the Brainlab product complies with the essential re-quirements of Council Directive 93/42/EEC (the “MDD”).Quentry for SRS Registry is a part of Quentry, which is a Class I product ac-cording to the rules established by the MDD.

Report Incidents Related to This Product

You are required to report any serious incident that may have occurred related to this product toBrainlab, and if within Europe, to your corresponding national competent authority for medicaldevices.

Sales in US

US federal law restricts this device to sale by or on the order of a physician.

Legal Information


https://www.brainlab.com/patent/

No Medical Advice

Neither Brainlab nor Quentry provide any medical advice. Customer is solely responsible for allmedical decisions, including but not limited to the interpretation of any patient data, and anydiagnosis, treatment or treatment plan made by the customer in connection with the use ofQuentry. The customer acknowledges that image capture, image processing and image displayalso depend on the customer's specific computer hardware environment and correspondingsystem settings which are beyond reasonable control of Brainlab. Brainlab does not warrant thatthe image representation through Quentry will be free from any errors such as image distortions,color deviations or poor contrast and brightness values. It is the sole responsibility of the customerand any other user, physician or medical physicist involved to anticipate the possibility of suchdisplay errors in interpreting images visualized through Quentry.

GENERAL INFORMATION


1.3 Symbols

Warnings

WarningWarnings are indicated by triangular warning symbols. They contain safety-criticalinformation regarding possible injury, death or other serious consequences associatedwith device use or misuse.

Cautions

Cautions are indicated by circular caution symbols. They contain important informationregarding potential device malfunctions, device failure, damage to device or damage toproperty.

Notes

NOTE: Notes are formatted in italic type and indicate additional useful hints.

Symbols


1.4 Using the System

Intended Use

Quentry.com is indicated for image data transfer and online storage of medical images andrelated data.Quentry.com is a web-based software for medical professionals that:• Supports doctors to build their global clinical network• Provides an online community, to work in virtual groups, send messages• Provides doctors with tools for secure online image (DICOM) storage, review, and sharing• Provides users with tools for aggregation and graphical visualization of patient data collected

within QuentryIt is not intended for primary diagnosis, detailed treatment planning or treatment of patients.Quentry for SRS Registry provides data capture, storage, enrichment and processing ofradiotherapy and stereotactic radiosurgery data related to patients, diseases, treatments andfollow-ups from various systems.

Intended Patient Population

No restrictions in patient population.

Intended Use Environment

The intended environment is a clinical planning office.

Intended User Profile

The device is generally used by medical professionals and medical organization support staff suchas doctors, their assistants or nursing staff, within a hospital, a clinic, a doctor's office or fromremote locations, such as at home.

Plausibility Review

WarningBefore patient treatment, review the plausibility of all information input to and output fromthe system.

GENERAL INFORMATION


1.5 Compatibility with Software

Compatible Brainlab Medical Software

Quentry for SRS Registry is compatible with the following Brainlab medical software:

Brainlab Medical Software Comment

Patient Data Manager Patient data management software

Viewer Used for viewing DICOM images and Brainlab treat-ment plans and comparing image sets.

iPlan RTiPlan RT Dose

Quentry for SRS Registry can read treatment planswritten by these applications as long as the loadingcriteria specifications in the user guide are met.

Multiple Brain Mets SRSImage FusionSmartBrushCranial SRS

Compatible Brainlab Elements. Quentry for SRSRegistry can read treatment plans created by Multi-ple Brain Mets SRS or Cranial SRS, objects creat-ed by SmartBrush and fusions created by ImageFusion.

Other compatible Brainlab software may become available after the release of this user guide. Ifyou have questions regarding compatibility of software with Quentry for SRS Registry contactBrainlab support.

WarningOnly Brainlab medical software specified by Brainlab may be installed and used with thesystem.

Non-Brainlab Software

Only authorized Brainlab employees may install software on the Brainlab system. Do notinstall or remove any software applications.

Updates

WarningUpdates to the operating system (hotfixes) or third-party software should be performedoutside clinical hours and in a test environment to verify correct operation of the Brainlabsystem. Brainlab monitors the released Windows hotfixes and will know, for some updates,if problems can be expected. Contact Brainlab support if any problems to operating systemhotfixes are encountered.NOTE: This only applies to workstations or servers with the Cranial Contouring workflow orQuentry Gateway installed.

Virus Scanning and Malware

Brainlab recommends protecting the system with state-of-the-art anti-virus software.Be aware that some malware protection software (e.g., virus scanner) settings can negativelyaffect system performance. For example, if real-time scans are performed and each file access ismonitored, then loading and saving patient data may be slow. Brainlab recommends disablingreal-time scans and performing virus scans during non-clinical hours.

WarningEnsure that your anti-virus software does not modify any Brainlab directories, specifically:• C:\Brainlab, D:\Brainlab, F:\Brainlab, etc.

Compatibility with Software


• C:\PatientData, D:\PatientData, F:\PatientData, etc.

WarningDo not download or install updates during treatment planning.Contact Brainlab support for further information regarding any of these issues.NOTE: This only applies to workstations or servers with the Cranial Contouring workflow orQuentry Gateway installed.

Microsoft Security Updates for Windows and Driver Updates

Brainlab allows the installation of security patches only. Do not install service packs and optionalupdates. Verify your settings to ensure updates are downloaded and installed correctly and at asuitable time. Do not update drivers on Brainlab platforms.See the Brainlab website for more information about settings and a list of Microsoft SecurityUpdates blocked by Brainlab support.Address: www.brainlab.com/updatesPassword: WindowsUpdates!89NOTE: This only applies to workstations or servers with the Cranial Contouring workflow orQuentry Gateway installed.

GENERAL INFORMATION


https://www.brainlab.com/updates/

1.6 Training and Documentation

Responsibility

WarningThis system solely provides assistance to the healthcare professional and does notsubstitute or replace the healthcare professional's experience and/or responsibility duringits use. It must always be possible for the user to proceed without the assistance of thesystem.Only trained medical personnel may operate system components and accessory instrumentation.

Reading User Guides

This guide describes complex medical software or medical devices that must be used with care.It is therefore important that all users of the system, instrument or software:• Read this guide carefully before handling the equipment• Have access to this guide at all times

Intended Audience

Quentry.com is aimed at medical professionals (physicians, their staff, nurses, etc.) with sufficientunderstanding of the English technical vocabulary related to the fields of medical physics andmedical imaging so as to enable appropriate understanding of the Quentry.com user interface.

Available User Guides

User Guide Contents

Patient Data Manager Soft-ware User Guide

Detailed software instructions on Content Manager and PatientBrowser.

Image Fusion SoftwareUser Guide Detailed software instructions on Image Fusion.

SmartBrush Software UserGuide Detailed software instructions on SmartBrush.

Quentry for SRS RegistrySoftware User Guide Detailed software instructions on Quentry for SRS Registry.

Quentry.com SoftwareUser Guide Detailed software instructions on Quentry.com.

Viewer Software UserGuide Detailed software instructions on Viewer.

Training and Documentation


1.7 Technical requirements

Quentry

Refer to the Quentry.com and Quentry Gateway Software User Guides.

Cranial Contouring Workflow

Refer to the Patient Data Manager, SmartBrush, Viewer and Image Fusion Software UserGuides.

GENERAL INFORMATION


1.8 Abbreviations

Abbreviations

This user guide contains the following abbreviations:

Abbreviation Explanation

AANS American Association of NeuroSurgeons

CTV Clinical Target Volume

CT Computed Tomography

MR Magnetic Resonance

NPA NeuroPoint Alliance

OAR Organs at Risk

PET Positron Emission Tomography

PTV Planning Target Volume

RT Radiotherapy

SRS Stereotactic Radiosurgery

SRT Stereotactic Radiotherapy

WBRT Whole Brain Radiotherapy

Abbreviations


2 PREPARATION AND DATAUPLOAD

2.1 About SRS Registry

Background Information

The Stereotactic Radiosurgery Registry (SRS Registry) is a joint project of the AmericanAssociation of Neurological Surgeons (AANS), NeuroPoint Alliance (NPA) and Brainlab. It hasbeen developed to collect data on the SRS treatment of:• Brain metastases• Benign brain tumors• Arteriovenous malformations (AVMs)

The registry objectives are to:• Define national patterns of care in radiosurgery• Improve healthcare outcomes• Support informed decision making

The AANS created the NPA as a not-for-profit corporation to coordinate projects involving theacquisition, analysis and reporting of clinical data.

Overview of Data Collection

Data fields for the SRS Registry are defined by a scientific committee organized by the NPA. Theregistry collects data on various patient events, such as SRS/SRT treatments, WBRT, surgicalresections and follow-up examinations.The collected data includes:

SRS/SRT Treatments Patient Baselines and Follow-Up

• Lesion volumes and locations• Dose distribution for treated lesions and or-

gans at risk (OARs)• Dose fractionation• Treatment device configuration details

• Lesion volume changes and recurrence• Neurological examination findings• Patient quality of life measures• Adverse events• Survival rates

For further information on data collected, refer to the NPA Stereotactic Radiosurgery RegistryData Dictionary.

How Data is Collected

Quentry and Elements technologies facilitate collection and automated structuring of this complexdata, reducing data entry errors.The process of collecting clinical and imaging data is outlined below.

PREPARATION AND DATA UPLOAD


Step

1. Depending on the event type, data is uploaded to Quentry for SRS Registry:a) SRS/SRT and WBRT treatment data is uploaded via your treatment planning systemconforming to DICOM standards.b) Tumor outlining for surgical resection and follow-up events are uploaded via the CranialContouring workflow or a third-party planning/contouring system. Surgical resection andfollow-up events are uploaded either via the export function of Patient Data Manager ordirectly from the third-party planning/contouring system.

2. Quentry for SRS Registry is used for entry of clinical data using web-based case reportforms, image data enrichment and processing, and storage.

3. The registry data is aggregated, de-identified and reported to the NPA for analysis andquality control. It is available for export or analysis using Analytics or Patient Dash-board.

About SRS Registry


2.2 Data Requirements


Data must be prepared in a specific manner and meet certain criteria for upload to the SRSPatient Registry. You must enter certain parameters into Quentry for SRS Registry, such asNumber of Fractions and Date of Treatment. Therefore, it is recommended to have a printoutfrom the treatment planning system available.NOTE: Certain fields may be automatically populated and will not require user data entry,depending on the source treatment planning system.

Treatment Plan Preparation

Prepare treatment plans as follows:• Include an MR dataset (recommended).

NOTE: If no MR data set is available, automatic OAR segmentation and dose calculation arenot available.

• Outline both the CTV and PTV (recommended).• Name each CTV and PTV meaningfully.• Export DICOM message types: RT Dose, RT Structure Set and RT Plan.

NOTE: It is not possible to import multiple RT Dose, RT Structure Set or RT Plan instancessimultaneously.

• Ensure that all patient data contains the same patient name, ID, date of birth and gender.• Export the complete dose and not just the dose around certain structures.

NOTE: The dose matrix must be defined for the entire tissue.

Preparation of MR Datasets

Quentry for SRS Registry requires MR data sets for the automatic segmentation of OARs.For optimal automatic segmentation, prepare the MR data set according to the following MRscanning parameters:

General MR ImagingRequirements

• High tissue contrast resolution• High signal-to-noise ratio• Always use 3D distortion correction if available

MR Scan Instruc-tions

To achieve the best segmentation results in the cranial region, it is recom-mended to provide at least a T1 and a T2 or FLAIR sequence-based scanwith the following parameters:MR T1 complete head (e.g., MPRAGE):• ≤ 1 mm slice resolution• ≤ 1 mm slice thickness• > 100 slices of the complete head

MR T2 and/or FLAIR:• ≤ 2 mm slice resolution• Full region of interest included



Data Requirements by Event Type

Event Type Data Requirements

SRS/SRT

• Patient's approved SRS/SRT treatment plan• Associated MRI and CT (if used in planning) scans• Image fusion/registration if available

NOTE: If no fusion is available and treatment planning is based on a CTdata set, dose calculation on automatically segmented OARs will not beavailable.

WBRT

• Patient's approved RT treatment plan• Associated MRI and CT (if used in planning) scans• Image fusion/registration if available

NOTE: If no fusion is available and treatment planning is based on a CTdata set, dose calculation on automatically segmented OARs will not beavailable.

Surgical Resection

If surgery took place before SRS/SRT treatment:• Patient's pre-operative MRI scan• Outlined tumor object(s)

If surgery took place after SRS/SRT treatment:• Patient's post-operative MRI scan• Outlined residual tumor object(s)

Follow-Up• MRI scan taken at time of follow-up examination• Outlined tumor object(s) (e.g., new, residual or recurring)

Data Requirements


2.3 Import Criteria

DICOM Data Types Supported by Quentry for SRS Registry

Data type Description

RT Plan Contains treatment plan parameters and a reference toan RT Structure Set.

RT Structure Set Contains objects created upon treatment plan exportfrom treatment planning software.

RT Dose Contains the dose information.

REG Contains registrations.

MR, CT, PET Image data

Segmentation Contains created objects (e.g, with SmartBrush).

NOTE: It is only possible to import orthogonal image series of RT Structure Sets.

NOTE: DICOM RT export data is supported, however, the Brainlab proprietary file format, xbrain isnot supported.

NOTE: After import, verify that the contours are properly aligned to the images.

Importing Treatment Plans

To upload dose volumes to Quentry for SRS Registry, the following criteria must be met inDICOM:

Criteria Technical Details in DICOM Terminology

The dose volume to be loaded must representthe overall dose of a single radiotherapy plan.

Dose Summation Type must be PLAN.Doses calculated for two or more RT Plans(MULTI_PLAN) and doses that do not repre-sent the entire plan (FRACTION, BEAM, CON-TROL_POINT) will be rejected.Type BRACHY will be rejected.

The dose must be given in gray units. Dose Units must be GY, not RELATIVE.

Only physical (not effective) and prescriptiondose can be loaded.

Dose Type must be PHYSICAL, and not EF-FECTIVE or ERROR.Dose Reference Structure Type POINT is notsupported.

Image data associated with the dose must beavailable.

An image series must be available that can betraced back via RT Structure Set/RT Plan to in-stances that were exported alongside the doseand resides in the same coordinate system(Frame of Reference).

Associated images must be of modality MR,CT or PET.

Image modalities currently not supported in-clude NM (Nuclear Medicine), XA (X-ray An-giography) and RTIMAGE (Radiotherapy Im-age).

No single pointsImport of single points like MARKER, ISOCEN-TER and REGISTRATION through the DICOMRT Structure Set is not supported.

Further information can be found in the DICOM conformance statement http://www.brainlab.com/dicom.



http://www.brainlab.com/dicom

http://www.brainlab.com/dicom

2.4 Exporting Data from Treatment Planning Systems


There are various ways data can be uploaded to Quentry:• Manual upload from the Quentry web portal• Export from Patient Data Manager• Export from treatment planning system• Upload from local folder using Quentry DICOM Utility

NOTE: Ensure all data of a patient event is uploaded together in one upload.

Exporting Data by Event Type

Event Type Exporting Data

SRS/SRT

Data is exported from treatment planning system via QuentryGateway to Quentry for SRS Registry.NOTE: If your treatment planning system does not support theexport of all relevant imaging data, store all data in a local fold-er and upload it to Quentry for SRS Registry using QuentryDICOM Utility.

WBRT

Data is exported from treatment planning system via QuentryGateway to Quentry for SRS Registry.NOTE: If your treatment planning system does not support theexport of all relevant imaging data, store all data in a local fold-er and upload it to Quentry for SRS Registry using QuentryDICOM Utility.

Surgical Resection

Data can be exported:• Using Cranial Contouring workflow and export to Quentry for

SRS Registry using the Patient Data Manager export func-tionality, or

• From third-party planning/contouring system.

Follow-Up

Data can be exported:• Using Cranial Contouring workflow and export to Quentry for

SRS Registry using the Patient Data Manager export func-tionality, or

• From third-party planning/contouring system.

Exporting Data from Treatment Planning Systems


2.5 Cranial Contouring Workflow

Events

The Cranial Contouring workflow can be used to outline new or residual lesion volumes forsurgical resection or follow-up events.

Event Type Description

SurgicalResection

Upload surgical image data and object information only. If surgery took place before SRS/SRT treatment:• Outline the pre-operative tumor volume on the pre-operative scan in Smart-

Brush and export the data to Quentry.If surgery took place after SRS/SRT treatment:• Outline the residual tumor volume on the post-operative scan in SmartBrush

and export the data to Quentry.

Follow-Up Upload follow-up image data and object information only. Outline the new tumorvolume on the follow-up scan in SmartBrush and export the data to Quentry.

Element Functions

① ② ③

Figure 1

The Cranial Contouring workflow consists of three steps within Elements:• ① VIEWING• ② CO-REGISTRATION• ③ CONTOURING

No. Element Function

① Viewer (optional): View DICOM data available for the selected patient.

② Image Fusion (optional): Fuse the MR data set to previous data sets.

③

SmartBrush: Outline tumor volumes.• Surgical resection:

- If surgery took place before SRS/SRT treatment, outline the pre-operative tumorvolume.

- If surgery took place after SRS/SRT treatment, outline the residual tumor volume.• Follow-up: Outline the new tumor volume.

NOTE: You can import previously contoured objects from third-party systems into theCranial Contouring workflow by pushing the data using a DICOM network connectionusing BL_IMPORT as AET at Port 104. Any DICOM RT data that is pushed to thisAET is evaluated for import conversion. For details, refer to the DICOM ConformanceStatement at: http://www.brainlab.com/en/DICOM. RT Structure Set contours of typePOINT are not imported.



NOTE: For more information on the Element functions, see the Viewer, Image Fusion andSmartBrush Software User Guides.

How to Export Data to Quentry

Once lesion volume contouring is complete, the data can be exported to Quentry.

Step

1. ①

Select Export ①.

2. ①

②

If there are data sets or contoured objects selected that do not belong to the current eventand have previously been uploaded to Quentry, deselect them by selecting X ①. This en-sures they are not uploaded twice.

3. Select Export ②.



Step

4.

Select Quentry as the export destination.The patient data is uploaded to Quentry for SRS Registry.

5. You receive an email notification when the data upload and processing has finished. Youcan then complete the associated tasks that are created for the uploaded event in Quen-try.





3 USING QUENTRY FOR SRSREGISTRY

3.1 Getting Started

Activating Your User Account

If you do not have a Quentry user account, you can sign up for free on the Quentry.comhomepage. Refer to the Quentry.com Software User Guide for more information on:• Creating an account• Activating your account• Logging in

USING QUENTRY FOR SRS REGISTRY


3.2 Tasks

About Tasks

Figure 2

The Tasks screen provides an overview of all patients that have tasks that require completion.

①

Figure 3

To see the tasks for each patient, select the arrow on the corresponding patient row ①.

Tasks


Patient Tasks

Figure 4

When a new patient is uploaded to Quentry for SRS Registry for the first time, two forms requirecompletion:• Baseline form• Disease form

Event Tasks

Figure 5

For every event upload, there is a New Event task, which requires that the event type beselected. There are four event types:• SRS/SRT• Follow-Up• Surgical Resection• Whole Brain RT

Depending on the event selected, two additional forms for the patient are added to Tasks.

Event Selection Forms

SRS/SRT• SRS/SRT Treatment Details• Lesion Definition

Whole Brain RT• Whole Brain RT Treatment Details• Lesion Definition

Surgical Resection• Surgical Resection Treatment Details• Lesion Definition

Follow-Up• Follow-Up Details• Lesion Definition



Status of Tasks

These indications provide an overview of the status of each task in the Tasks screen.

Status Description

! This warning indicates that there are emptymandatory fields in a form.

A progress bar is displayed beside the task toshow the percentage of the task or form that iscomplete.

Submitting Tasks

Figure 6

Once all mandatory fields of a form or task are complete, Submit becomes enabled.

Figure 7

After selecting Submit, you are prompted to CONFIRM TASK SUBMISSION by selecting OK.The task is then removed from the Tasks screen and data will be considered for Analytics andreported to the NPA.NOTE: Both the treatment/follow-up details and Lesion Definition forms must be completed forSubmit to be enabled for the event task.

Tasks


3.3 Forms

Patient and Event Forms

There are two forms that are completed on patient level and two categories of forms that arecompleted on event level. All forms can be accessed or edited from the Tasks screen or thePatients screen.

Patient Forms Event Forms

• Baseline• Disease

• Treatment/follow-up details:- SRS/SRT Treatment Details- Whole Brain RT Treatment Details- Surgical Resection Treatment Details- Follow-Up Details

• Lesion Definition

Navigating Forms

Select the relevant button to enable the function when navigating forms.

Button Function

Navigates to the next section of the form.

Navigates to the previous section of the form.

Saves any information that has been entered in the form. You cansave intermittently.

Exits the form and goes back to the previous screen.



How to Complete the Baseline Form

Figure 8

Step

1. Complete all sections of the baseline form:• 1. Patient Conditions• 2. Neurological Exam Cranial Nerves• 3. Neurological Exam Motor Sensory/Sensory System• 4. Pre-SRS Treatment(s)• 5. Comments

To navigate to the different sections:• Select Next or Back, or• Select the section title

2. Select Save intermittently to save your work and once the form is complete.NOTE: This does not submit the form.

How to Complete the Disease Form

Step

1. Select a Disease Group, then select a Disease Name.

Forms


Step

2. Based on the selections, additional mandatory fields pop-up.

3. Complete all mandatory fields marked with an asterisk.

4. Select Save.

How to Add Multiple Diseases in Tasks Screen

The option to add multiple diseases is enabled once all mandatory fields for the initial disease arefilled in.

Step

1. Select the Disease task again.This will bring you to the Disease form again.

2. Once all fields are completed, select Save.The new disease will appear below the task on the Tasks screen.

How to Add Multiple Diseases in Patients Screen

The option to add multiple diseases is enabled once all mandatory fields for the initial disease arefilled in.

Step

1. Select the relevant patient row.This opens all patient level forms associated with the patient.

2. Select + Add next to the Disease form or select the form itself.



How to Complete the Treatment/Follow-Up Details Form

Step

1.

The fields and sections to be completed in the form depend on the event.To navigate to the different sections by:• Select Next or Back or,• Select the section title

2. After completing a section, select Next.

3. Select Save intermittently to save your work and once the form is complete.NOTE: This does not submit the form.

How to Complete the Lesion Definition Form for SRS/SRT Events

Step

1.

Upon entering the form, 1. PTV Selection opens.NOTE: You are not able to navigate further until this section is complete.

2. Select all target volume(s)/PTV(s) .

3. Select Next.

Forms


Step

4.

Complete 2. CTV/PTV Matching & PTV Details by filling in the properties for the treat-ment and target volume (PTV) and by selecting the matching CTV(s).Adjust the lesion Location(s), if necessary.

5. Select Save.

How to Complete the Lesion Definition Form for WBRT Events

Step

1.

Upon entering the form, 1. PTV Selection opens.NOTE: You are not able to navigate further until this is complete.

2. Select the target volume (PTV).

3. Select Next.



Step

4.

Complete 2. CTV/PTV Matching & PTV Details by filling in the properties for the treat-ment and target volume (PTV) and by selecting the matching CTV of the whole brain, ifavailable.

5. Select Save.

How to Complete Lesion Definition Form for Surgical Resection Events

②

③

①

Figure 9

Step

1. Deselect all objects that do not represent lesions ①.

2. Fill in lesion properties and adjust the lesion Location, if necessary ②.

3. Select Save ③.

Forms


How to Complete Lesion Definition Form for Follow-Up Events

①

③

②

Figure 10

Step

1. Deselect all objects that do not represent lesions ①.

2. Fill in lesion properties and adjust the lesion Location, if necessary ②.

3. Select Save ③.



3.4 Patients

About Patients

All uploaded patients are listed on the Patients screen. Select My CareTeams from the Patientslist to view all patients in your CareTeams.

Figure 11

How to View or Modify Patient Level Forms

①

②

Figure 12

Step

1. Select the relevant patient row on the Patients screen ①.This displays all patient level forms associated with the patient on the right hand side ②.

2. Select a particular form to review or edit its content.

Patients


How to View or Modify Event Level Forms

Step

1. In the Patients screen, select the patient's name or select the patient row, then Next.This opens all folders associated with this patient.

2.

①

Select a particular folder to review. This displays all event level forms associated with thepatient folder on the right hand side ①.

3. Select the form you would like to review or edit.

How to Update Patient Vital Status

The default for a patient's vital status is Alive. If a change in a patient's vital status occurs, itshould be updated.

①

②

Figure 13

Step

1. Select the row of the relevant patient ①.



Step

2. Select the Vital status form ②.

3. Select either:• Lost to follow-up• Deceased

4.

If Deceased is selected, also complete:• Date of Mortality• Cause of Mortality

5. Select Save.

Patient Dashboard

Figure 14

The Dashboard allows healthcare professionals to review the history and analyze the data for aparticular patient.The patient dashboard displays a timeline of all events, as well as the following event-based timeseries charts:• Total Lesion Volume• Toxicity (CTCAE)

Patients


• Karnofsky Performance Status• EQ-5D

Other Functionalities

For all other functionalities, refer to the Quentry.com Software User Guide.



3.5 Analytics

Overview

Analytics allows healthcare professionals to analyze the data of the entire population in theiraccount.

Figure 15

Analytics enables a graphical visualization of all submitted data and a means to export allmetadata contributed by the users belonging to the account. A set of graphs are available withwhich you can perform additional filtering and create subsets of these graphs.

Dashboard

①

Figure 16

The DASHBOARD ① tab is where all saved graphs and charts created in Analytics are located.

Analytics


How to Analyze Population Data

Step

1. ①

Select the category of data to be analyzed by selecting the corresponding arrow ①, thenselect the criteria.• POPULATION (e.g., gender, age, vital status)• OUTCOMES (e.g., toxicity, lesion hemorrhage)• DATA QUALITY (e.g., submitted events)

2. ①

②Fill in the appropriate fields in FILTERS and select APPLY ②.

3. Select the type of chart for displaying the data ①:• Column chart• Pie chart• Line chart

NOTE: The chart types available are dependent on the selected data category and crite-ria.



Step

4. ①

Optional: Select the pin ① to define the chart name and save to DASHBOARD.

How to Add Layers to Charts

① ② ③

Figure 17

Step

1. Select + ADD LAYER.

2. Fill in the appropriate filters based on the data criteria you would like to analyze in the lay-er and select APPLY.

3. Edit layer properties as desired:• Edit layer name ①• Hide/unhide layer ②• Delete layer ③

How to Export Data to a CSV File

Step

1. Select the arrow beside EXPORT.

Analytics


Step

2.

Select either Use patient details or De-identify details.

3. When prompted, select Save.

4. Select one of the following options:• Open• Open folder• View downloads

How to Remove a Chart from the Dashboard

Step

1. ①

Select X ① on the chart you would like to remove.

2. When prompted, select OK to remove the chart.



3.6 Patient Follow-Up Report

About the Patient Follow-Up Report

Figure 18

The PATIENT FOLLOW-UP REPORT provides a list of patients requiring a follow-up appointmentbased on timeframes entered in the treatment details/follow-up details forms.

How to Generate a Patient Follow-Up Report

Step

1. Select user name.

2.

Select Reports.

3. Select the PATIENT FOLLOW-UP tab.

4. Select Time Range and Vital Status filters to be applied to results.

5. Optional: To export results to a CSV file, select EXPORT.

Patient Follow-Up Report


3.7 User and Account Settings

Managing Your User Profile

Refer to the Quentry.com Software User Guide for further information on:• Accessing the settings screen• Changing your user details• Changing your password

Managing Your Account Settings

Refer to the Quentry.com Software User Guide for further information on:• Account settings• CareTeam management



User and Account Settings


INDEXA

American Association of Neurological Surgeons....................... 15

Ccareteam management.............................................................. 45careteams...................................................................................36compatible Brainlab medical software........................................10

Ddashboard.................................................................................. 41data analysis.............................................................................. 40data preparation......................................................................... 18DICOM data supported.............................................................. 19Dose Review.............................................................................. 16

EElement functions.......................................................................22events....................................................................................20,21

Ffollow-up..................................................................................... 21

NNeuroPoint Alliance....................................................................15

Ppatient deceased........................................................................ 38

RRegistry Uploader.......................................................................16

SSRS Registry project.................................................................. 16support......................................................................................... 5surgical resection....................................................................... 21

Tthird-party plans..........................................................................19

Uuser account...............................................................................25

Vvital status.................................................................................. 29

INDEX


brainlab.com

Art-No. 60919-84EN

*60919-84EN*

Documents

Quentry for SRS Registry 3 · Quentry for SRS Registry can read treatment plans written by these applications as long as the loading criteria specifications in the user guide are