Q O ing Fai8al0 Inter~~~~natio-nal Prize

AN INVITATIONU TO SUBMIT NOMINATIONS FOR THE 1990

KING FAISAL INTERNATIONAL PRIZEIN SCIENCE

O The General Secretariat of the King Faisal InternationalPrize has the pleasure of inviting universities, academies,educational institutions and research centers throughout theworld to nominate qualified candidates for

the King Faisal International Prize in Science, in the field of

2 ~"CHEMISTRY"0 1. A nominee (a living person) must have accomplished an 0

outstanding academic work on the Prize topic; benefitingmankind and enriching human thought in the prize field. 0

2. The work submitted must be original and published.3. The work submitted must not have been previously

awarded a prize by any international organization.4. Nominations by individuals or political parties will not be

accepted.5. Nominations should include:

(a) An official letter by a recognized educational institu-tion, to each nominee, indicating the nominated 0works.

(b) Typed C.V. of the nominee's academic background,experience and published works. 0

(c) Ten copies of the works submitted for nominations.(d) A copy of the nominee's educational certificates. 0(e) Three recent colored photos 10 x 15 cm (4" x 6").(f) Full address and telephone number.

6. Nominations will be evaluated by a Selection Committeeconsisting of highly recognized specialists in the field. 0

0 7. More than one person may share the Prize. 08. The winners' names will be announced in January 1990,

and the Prize will be awarded in an official ceremony atthe headquarters of the King Faisal Foundation in Ri-yadh, Saudi Arabia, at a later date.

K 9. The Prize consists of: 0(a) A certificate in the winner's name containing an ab-

stract of the work that qualified him/her for thePrize.

(b) A gold medal.(c) A sum of three hundred and fifty thousand Saudi Ri-

yals, (approximately US $93,333). 010. The latest date for receiving the complete nomination re-

quirements will be (1st of August, 1989).11. No nomination papers or works will be returned to the 0

senders, whether or not the nominee was awarded the

5 12. Ac e d e slprize.12 All correspondence must be sent by registered airmailto:0

The General Secretariat, King Faisal Intemational PrizeP.O. Box 22476, Riyadh 11495, Kingdom of Saudi Arabia

O11 Telephone: 4652255, Telex: 404667 PRIZE SJ,Fax No: 4658685, Cable: JAEZAH

0(J~c~-7~ o (Jr' c o 1DD cD c

REF-IlComputerizes your REFERENCES

and prepares your BIBLIOGRAPHIESO Maintains a data base of referencesO Searches for any combination of authors, years

of publication, reference title, publication title,keywords or abstract

O Formats bibliographies exactly as you want themO Reads your paper, inserts citations into the paper,

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E Downloads references from MedLine data basessuch as NLM, BRS and DIALOG (optional)

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MMAUAL 15t012DEMO020322 Prospect Ave., Hartford, CT 06106SYSTEMS (203) 247-8500Connecticut residents add 7 /2%'o sales tax.

Circle No. 54 on Readers' Service Card

Brain Structure, Learning, andMemoryEdited by Joel L. Davis and Robert W.Newburgh, Office of Naval Research, andEdward J. Wegman, George MasonUniversity

This new book, based on a AAAS Annual Meetingsymposium, explores the connections between cellularand computational approaches to understanding theneural basis of learning and memory. Incorporating suchdiverse ideas as invertebrate and computer-basedmodels, cerebellar involvement in motor engrams,learning, and the sensory sciences; nonstationary pointprocesses; and models closely tied to vertebrate neuralnets, the contributors not only shed new light onimportant brain functions but also provide an exampleof how neuroscience research should be structured.

$35.00; AAAS members $28.00 (include membership numberfrom Science). 301 pp., 1988. AAAS Selected Symposium 105.Order from: Westview Press, Dept. AAAS, 5500 Central Avenue,Boulder, CO 80301. (Add $2.50 postage and handling for thefirst copy, 75 cents for each additional copy; allow 4-6 weeksfor delivery.)

Published by Westview Press for AAAS

POSITIONS WANTED

Behavioral Research. Seeking position as postdoctoral,doctoral or assistant researcher. Background: M.D. withbroad behavioral sciences interests. B.S., M.B.A. degreesand M.P.H. studies. Box 11332, Norfolk, VA 23517.

Biochemist, M.S. Chemistry, Ph.D. expected June1989, seeks industrial position. Prior experience in bothacademic and industrial laboratories. Several publicationsfrom dissertation. Very broad biochemical, immuno-chemical, and molecular biology background. Box 55,SCIENCE.

POSITIONS WANTED

Cardiovascular Physiologist, Ph.D., seeks position inacademia at assistant professor level. Interest and back-ground in cardiac function during circulatory shock,myocardial ischemia. Seven years ofpostdoctoral experi-ence. Also excellent background in computers. Excellentteacher and research scientist. Curriculum vitae availableon request. Will also consider industry. Prefer Chicagoarea but will consider other locations. Box 52,SCIENCE.

Community Ecologist/Entomologist. Recent Ph.D.(arthropod influences on natural ecosystems) with abackground in plant ecology, biogeochemical cycling(nutrients, heavy metals, radionuclides), soil biology,statistics and population dynamics. Have 14 years ofexperience in terrestrial (from coastal to alpine) andwetlands ecosystems. Publications. Seeks research oppor-tunities in university systems or private sector. Box 56,SCIENCE.

Human Psychophysiologist, Ph.D. Research publica-tions, teaching, and postdoctoral experience in the social,perceptual, and biological foundations ofmotivation andemotion. Seeks academic position offering teaching andresearch opportunities. Box 53, SCIENCE.

Immunologist. Ph.D. Highly skilled scientist with expe-rience in cellular immunity in cancer and infectiousdiseases, hybridoma and monoclonal technology, and cellculture. Creative problem solver with excellent manage-ment and communication skills. Seeking position inacademic medicine or biotechnology R&D. Box 57,SCIENCE.

Molecular Biologist-Computational Genomist,Ph.D., 1978. Established investigator in computationalgenomics and molecular biology. Good publicationsrecord. Considerable computer work on gene structureand evolution. Development of algorithms and softwaresystems for analysis of genetic sequences and recombi-nant DNA. Currently working on application ofcompu-tational genomics to the Human Genome project: gene-detection algorithms, automation in mega-base sequenc-ing, database management systems for the analysis ofglobal genome organization and regulation in complexorganisms. Also working on computer simulations ofgene evolution mechanisms. Invites consultation. Seekslaboratory director/manager position in industry or ten-ured faculty position in academia. Box 58, SCIENCE.

Science Writer/Editor for free-lance assignments. Biolo-gy degree and broad science knowledge. Research andforeign language skills. Douglas Garner, Box 7956,Austin, TX 78713-7956.

POSITIONS OPEN

ASSISTANT PROFESSORANIMAL SCIENCE/SWINE NUTRITION

Tenure-track position beginning 1 September 1989 isavailable for a Ph.D. trained in non-ruminant nutrition.The position is approximately 2/3 teaching and 1/3research. Teaching and research will focus on improve-ment of swine productivity through nutrition and otherareas ofanimal science in the candidate's interest. Closingdate is 30 June 1989. Applicants should send a resume,transcripts, and three letters of recommendation to: Dr.Ronnie D. Green, Search Comnmittee Chairperson,Departmnt ofAnimal Science, Texas Tech Universi-ty,Lubbock, TX 79409-2141. TTU is an Equal Oppor-tunity/Affirmative Aaion Employer.

ASSISTANT PROFESSOR OF PHYSIOLOGYAND PHARMACOLOGY. Tenure-track positionavailable for 1 July 1989. Candidate should have Ph.D.and/or D.D.S., with qualifications and interest to teachdental and graduate students, and conduct researchprimarily in muscle/nervous system physiology (andpharmacology). Send letter of application, curriculumvitae, and names, addresses, and telephone numbers ofthree references to: Dr. Donald B. Doemling, Chair-man, Department of Physiology and Pharmacology,School of Dentistry, Loyola University Medical Cen-tcr, Maywood, IL 60153. Loyola University ofChicago isan Equal Opportunity/Affirmative Action Employer.

POSITIONS OPEN

ASSISTANT PROFESSORUNIVERSITY OF PIITSBURGH

SCHOOL OF MEDICINEDEPARTMENT OF PATHOLOGY

The Department of Pathology at the University ofPittsburgh School of Medicine has two openings at theassistant professor level for molecular biologists with aPh.D. and postdoctoral training. A strong background incloning and hybridization methods is desirable. Respon-sibilities will include the development of an independentresearch program, preferably in the area ofHLA genetic,as well as teaching in the Department's Graduate Pro-gram. The position is available 1 July 1989. Sendcurriculum vitae and three references to: Dr. ThomasJ. Gill III, Chairman, c/o A. Roman-Koller, Uni-versity of Pittsburgh School of Medicine, Depart-ment of Pathology, 776 Scaife Hall, Pittsburgh, PA15261. The University ofPittsburgh is an Equal OpportunityEmployer.

ASSISTANT PROFESSORUNIVERSITY OF MINNESOTA

The Department of Agronomv and Plant Genetics isrequesting applications for a tenure-track, 12-monthresearch and teaching position in weed ecology. Success-ful candidate will develop a weed ecology researchprogram. Research will encompass weed problems inagronomic crops, emphasizing ecological principles ofweed management, the development of principles ofcrop-weed competition, economic thresholds of weeds,an weed seed population dynamics. The individual willcooperate in developing integrated approaches to weedmanagement that will provide environmental protection,and maintain the profitabilitv and sustainabilitv of farm-ing enterprises. Collaboration research with other facultyis expected. The position involves graduate student train-ing and graduate/undergraduate teaching in weed ecolo-gy and plant taxonomy.Minimum qualifications include Ph.D. in a plant sci-

ence by date of appointment and documented researchexperience in terrestrial plant ecologv or weed popula-tion dynamics. Salarv is commensurate with qualifica-tions and experience. Benefits include health, dental, andfaculty life/disability insurance, social security, facultvretirement (2-year waiting period), and opportunities forsabbaticals and quarter leaves. Applications close 15 June1989. The position is available 1 July 1989, or as soonthereafter as possible. Applicants must send a resume, alltranscripts, reprints, a one- to two-page statement ofinterests related to this position, and have their letters ofreference sent independently to: Dr. Donald Wyse,University of Minnesota, Department of Agronomyand Plant Genetics, 411 Borfaug Hall, St. Paul, MN55108. All materials must be received by the closingdate. The University of Minnesota is an Equal OpportunityEducator and Employer atnd specifically intvites and encouragesapplications from women and minorities.

ASSISTANT PROFESSOR, MICROSCOPIST-GENETICIST: Biologv position available 1 August1989. Temporary position contingent on funding. Re-sponsibilities include participation in the undergraduateand graduate life science curriculum, including electronmicroscopy, genetics and genetic engineering. Supervi-sion ofM.S. students and development of an extramural-ly funded research program expected. Closing date: 28April 1989 or until filled. Submit letter of application,resume, official transcripts and three letters of referenceto: Biology Search Committee, School of Science andTechnology, New Mexico Highlands University, LasVegas, NM 87701. New Mexico Highlands University is asmall, state-supported university and is an Equial Opportuni-ty/Affirmative Action Employer.

ASSISTANT/ASSOCIATE PROFESSOR OFPHYSIOLOGY. Ph.D. in physiology required. Oppor-tunity for Chair of three-member Department. Primarilyteaching cardiovascular, muscle, and 1/2 neuro physiolo-gy to freshman medical students. Assist in weekty labora-tories. Emphasis on teaching excellence. Rank and salarycommensurate with qualifications. Start July or sooner.Send by 8 May 1989 curriculum vitae and letter plusnames, addresses, and telephone numbers of three pro-fessional references to: Dr. E. H. Whitten, Universityof Health Sciences, College of Osteopathic Medicine,2105 Independence Boulevard, Kansas City, MO64124. Telephone: 816-221-9698.

PERSONNEL PLACEMENT 375

PersonnelPlacement

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence. SCIENCE reserves the right, in its discretion, todecline to publish advertisements submitted to it.

UNE CLASSIFIED ADVERTISING DEADLINES:Thursday, 10 a.m., 2 weeks prior to issue date (mailedon issue date). For deadlines for display advertising,please contact Scherago Associates.

POSITIONS WANTED: 40¢ per word, plus $4 for use ofbox number, per week. $10 minimum, per week.Prepayment required. This rate is available only toindividuals seeking jobs.

UNE CLASSIFIED (POSITIONS OPEN, COURSES,FELLOWSHIPS, MARKETPLACE, and so forth):$40.00 per line; $400 minimum, per week (minimumcharge covers one inch on a single column; one inchequals 10 lines of 52 characters and spaces per line).No charge for use of box number. No agency commis-sion for ads less than 4 inches. No cash discount.Prepayment required for all foreign ads. Purchaseorders and/or cover letter including billing addressrequired for all other advertising.

To ESTIMATE ad cost:Structure ad copy on a separate page, on lines of 52characters and spaces. Include any desired heading.Each line of heading, and/or extra line spaces, and allpartial lines (including centered reply information) arecounted as full lines. Ad titles located within the textare printed in boldface caps and are only 32 charac-ters per line. In ESTIMATING the cost, multiply totallines x $40.00 = approximate cost of ad. (This is anapproximate cost ONLY: Allow for variation betweenestimated lines and actual typeset lines and the result-ing final cost. Purchase orders must allow for somedegree of flexibility and/or adjustment.)

CANCELLATION POLICY:NOTE: Ad cancellations made after Thursday, TWOweeks prior to issue date incur a 10% productioncharge. Final deadline for cancellations is 12 p.m.Tuesday, ONE week prior to issue date. Cancellationsmust be in writing.

Send copy for- all Positions Wanted ads and UneClassified ads less than 1/6 page in size (39 lines) to:

SCIENCE Classifled Advertising1333 H Street, NW, Room 940

Washington, DC 20005Telophone: 202-326-6555

Send copy for Fractional DIsp1ay ads, 1/6 page andlarger, and all Marketplace ads to:

Scherago Associates, Inc.1515 Broadway

New York, NY 10036Telephone: 212-730-1050

Blind ad replies should be addressed as follows:

Box (give number)SCIENCE

1333 H Street, NWWashington, DC 20005

Biologist, Ph.D. (April 1989). Experience in proteinisolation, purification and characterization, includingHPLC. Seeking challenging postdoctoral position in alaboratory with ongoing research in protein chemistry.Box 47, SCIENCE.

21 APRIL I989

POSITIONS OPEN

The Department of Biology, The University of Ala-bama, invites applications for one or more tenure-trackpositions in molecular biology/molecular genetics at ei-ther the ASSISTANT OR ASSOCIATE PROFES-SOR level. Would also consider temporary 1-year ap-pointments or visiting professorships. Candidates musthave a Ph.D. and postdoctoral experience is preferred.Submit curriculum vitae and the names of three refer-ences by 30 May 1989 to: John K. Hardman, De-partennt of Biology, The University of Alabama,Box 870344, Tuscaloosa, AL 35487-0344. The Uni-versity ofAlabama is an Equal Opportunity/Afirmnative ActionEmployer.

ASSISTANT/ASSOCIATE PROFESSOR-RADIATION ONCOLOGY

Facilities located in a new Cancer Hospital, occupying30,000 square feet, include three Linacs, plus dedicatedintraoperative Linac, hyperthermia, HD Remote After-loading, dedicated CT scanner, two simulators, conven-tional and two 3-D Treatment Planning Workstations.Requirements: At least 1 year of experience in clinicalradiation oncology with demonstrated interest in aca-demic medicine. Send resume to: Dr. Reinhard A.Gahbauer, Radiation Oncology, Ohio State Universi-ty, Doan Hall N-089, 410 West 10th Avenue, Co-lumbus, OH 43210.

ASSOCIATE DIRECTOR FORTECHNOLOGY TRANSFER

The University ofGeorgia is accepting applications forthe position of Associate Director for Technology Trans-fer.

This position operates within the Industrial InterfaceProgram and is responsible for marketing and licensingintellectual property generated by University research.

Applicants should have a good working knowledge ofresearch and some business experience, preferably relatedto the protection and licensing of intellectual property. Aworking knowledge of computer science would be desir-able. Submit application an resume by 19 May 1989 to:Dr. John Ingle, Director, Industrial Interface Pro-gram, The University of Georgia, Office of the VicePresident for Research, Athens, GA 30602. An EqualOpportunity/Afirmative Action Institution.

ASSOCIATE RESEARCH SCIENTIST. Performresearch in the area of transposition and site-specificrecombination of bacterial transrosons in order to studvand analyze the mechanisms o these processes in vivoand in vitro. Must have a Ph.D. in mofecular biology orbiochemistry. No specific experience required. Requiresa strong background in classical and modern bacterialgenetics; microbiology; protein expression and analysis;DNA sequencing and mutagenesis (including computeranalysis of nucleic acid sequences); plasmid biology; andbacterial conjugation as evidenced by authored publica-tions for scientific journals or 2 years of independentresearch in the discipline. Monday through Friday; 9:00a.m. to 5:00 p.m.; $29,300 per annum. Send resume to:Job Service Technical Unit, Connecticut Departmentof Labor, 200 Folly Brook Boulevard, Wethersfield,CT 06109. Refer to Job Order #3046671.

DIRECTORNORTHWESTERN UNIVERSITYINSTITUTE FOR NEUROSCIENCE

Applications and nominations are invited for the Di-rectorship of the newly formed Institute for Neurosci-ence at Northwestern University. This is a University-wide institute whose members come from ten depart-ments spread across four schools and several teachinghospitals. Current Institute membership exceeds 50 fac-ulty. The Director will be expected to oversee theUniversity-wide commitment to further expand facultyand research activities in the neurosciences. The Directorwill become the incumbent of an endowed Chair inNeuroscience. Candidates are expected to be internation-ally recognized leaders in the field of neuroscience.Those interested should submit an up-to-date curricu-

lum vitae along with the names of four references to:Dr. Robert D. Goldman

ChairmanInstitute for Neuroscience Scarch CommitteeDepartment of Cell Biology and Anatomy

303 East Chicago AvenucChicago, IL 60611-3008

Northwestem University is an Affirmative Action/EqualOpportunity Employer.

POSITIONS OPEN

BIOLOGIST to plan, teach, and coordinate lecturesand laboratory/demonstrations in introductorv biologyand to supervise teaching assistants. Ph.D. in life sciencesrequired with strong interest and demonstrated excel-knce in undergraduate teaching. Ninc-month tenure-track appointment at assistantlassociate professor lcvelcommencing 28 August 1989. Salary competitive; exccl-lent fringe benefits Scnd curriculum vitae, transcripts,and three letters of recommendation by 31 May 1989 to:Personncl, Jacksonvillc State University, Jacksonvillc,AL 36265.

Jacksonville State University is an Equal Opportunity/Af-firmative Action Employer.

CEREBROVASCULAR RESEARCH SCIEN-TIST to join existing faculty in the study ofthe develop-ment, plastici and athology ofneurovascular function.The successf canddate will exhibit evidence of inde-pendent research productivity and the ability to attractexternal funding. Applicants should have experience withpharmacological, physiological and functional methodsrto complement present anatomical, biochemical, andimmunohistochemical techniques. Primary tenure-trackappointment will be in the Department of Neurosurgeryat the assistant or associate professor level. Please sendcurriculum vitae and have three letters of recommenda-tion forwarded to: Keith A. Cmtcher, Ph.D., ResearchDivision, Department ofNe gery, University ofCincnnat incinnat OH 45267.

Full-time CYTOGENETICS SPECIALIST to con-duct prenatal diagnosis that includes chromosome analv-sis from amniotic fluid cells, peripheral blood cel,villous chorion cells, fetus tissue culture cells usingmicroscopy. Must perform high resolution banding tech-nique, replication banding, fragile X analysis, R-bandingusing fluorescent microscopy and computer-assistedchromosome analysis. Involved in clinical aspects ofmolecular cytogenetics. Salary $22,000 per year. Musthave Bachelor's degree in biology and miimum of 3years of experience in the field of cytogenetics. Sendr6sume to: rgia Department ofLabor, 1275 Clar-endon Avenue, Avondale Estates, GA 30002, or to thenearest Georgia Job Service Center. Control #GA5346447.

DIRECTORDEPARTMENT OF BIOPHYSICS

The Johns Hopkins School of Medicine invites ap li-cations for the position of Professor and Director, Dle-partment of Biophysics. The department is expected toexpand its research and research training programs. Thesuccessful candidate will have a distinguished record ofscientific productivity in the field of structural biology.An earned doctorate and evidence of leadership abilityare required. Interested applicants should send theircurriculum vitae, bibliography and the names of threereferences to: Hamilton 0. Smith, M.D., Chairman ofthe Biophysics Search Committee, Johns HopkinsSchool ofMedicine, Room 502A Preclinical TeachingBuilding, 700 North Wolfe Street, Baltimore, MD21205. Equal Opportunity/Affirmative Action Employer.

HOWARD UNIVERSITYDIRECTOR OF UNIVERSITY LIBRARIESApplications are now being accepted for this position.

Appointments will begin 1 July 1989. Applicants shouldhave: an MLS degree or equivalent from an ALA-accredited institution and a second Master's degree orhigher; a doctorate in an academic discipline is desirable;a minimum of 10 years of professional experience,including at least 5 years ofadministrative expenence in amajor academic library. Salary will be commensuratewith qualifications and experience. Preliminary screeningwill begin 1 April 1989. Applications and nominationsshould be sent to: Dr. W,fl,am A. Sadler, Chairman,Review and Advisor Committee, Graduate School ofArts and Sciences, Office of the Dean, Howard Uni-versity, Washington, DC 20059. Applicants must in-dude a current resume and names, adrs, and tele-phone numbers of at least three references. To expediteapplication, three recommnendation letters are to be sentdirectly to the above address. Howard University is anAfirmative Action/Equal Opportunity Employer.

POSITIONS OPEN

ENDOWED CHAIRCANCER RESEARCH

This is a senior position for an established investigatorwho will conduct his/her own program of research andcollaborate with other basic and clinical investigators inthe new Arthur G. James Cancer Hospital and ResearchInstitute at The Ohio State University College of Medi-cine.The Wing Chair of Surgical Oncology will support a

Ph.D. and/or M.D. at the associate or fu0l professor levelin the Department of Surgery whose primary interest isdirected toward the development of the modern tools ofcellular and molecular biology and their applications tothe therapeutic treatment of cancer.The Committee will begin reviewing nominations and

applications on 1 April 1989 and continue until acandidate is chosen.

Please supply curriculum vitae and names and tele-phone numbrs of three references: William B. Farrar,M.D., Director, Division of Surgical Oncology, DoanHall N-907, 410 West 10th Avenue, Columbus, OH43210.The Ohio State University is an Equal Opportunity Employer.

ENVIRONMENTAL ENGINEERTexasgulf Inc., Aurora, North Carolina, has an imme-

diate opening for an environmental engineer. The idealcandidate will have a M.S. degree in environmentalengineering or environmental science, and have an inter-cst in dealing with groundwater studies and containmentand control programs for solid and hazardous wastedisposal. Primary responsibilities will include stayingcurrent on environmental a encv regulations, obtainingregulatory pennits and developing compliance programs.Excellent salary and benefit package. If interested, sendrcsumc to:

Recruiting SupervisorTezasgulf Inc.P.O. Box 48

Aurora, NC 27806Equal Opportunity Employer M/F.

ENVIRONMENTAL SPECIALIST IVPalatka, Florida. Salarv $29,000, the St. Johns River

Water Management District has an opening in appliedriverine or estuarine ecology. Primarv responsibility is toprovide scientific direction in the development and im-plementation of a program to restore and preserve thelower basin of the St. Johns River. Bachelor's degree inthe biological sciences and 7 years ofexperience required.Advanced degree with specialization in estuarine/nverineecology/sediment-water colunn interactions preferred.Send resume with source of ad by 15 May 1989 to: St.Johns River Water Management District, Office ofEmployee Relations, P.O. Box 1429, Palatka, FL32078-1429.

Equal Employment Opportunity/Affirmative ActionEmployer/Veterans Preference.

EXPERIMENTAL PATHOLOGYThe Department of Pathology, Emorv Universitv

School of Medicine, is expanding its program in expen-mental pathologv. We seek candidates at the ASSIST-ANT OR ASSOCIATE PROFESSOR level, tenuredor tenure-track to undertake research in the areas offundamental immunobiology, autoimmunitv, transplan-tation biology, and tumor immunology. Experience withmodern techniques of molecular biology and cellularimmunology would be important determining factors.The incumbent is expected to undertake an active pro-gram of research in experimental pathology. Candidateswho have successfully competed for peer-reviewedgrants, or have ongoing programs, which would lead tosuch support, will receive preference. The incumbent willbe expected to participate in a program of graduateeducation, at the Ph.D. and/or Master's level in experi-mental pathology. Please send curriculum vitae andnames of five references to: Kenneth W. Sell, M.D.,Ph.D., Professor and Chairnan, Department of Pa-thology and Laboratory Medicine, 703 WoodruffMemorial Building, Atlanta, GA 30322. Emory Uni-versity is an Equal Opportunity/Afirmative Acion Employer.Women and minorities are encouraged to apply.

SCIENCE, VOL. 244376

The Elmer V. McCollum ProfessorandChair

Department of BiochemistryThe Johns Hopkins University

School of Hygiene and Public HealthApplications and nominations are invited for the position of Chairperson of theDepartment of Biochemistry at the Johns Hopkins School of Hygiene and PublicHealth. The general research interests of the current faculty include: Biochemis-try-enzyme structure and mechanisms; peptide chemistry; chromatin andnucleic acid chemistry; mechanisms of nucleic acid replication, recombinationand repair; structure and function of cell surface molecules; somatic mutationand antibody diversity; cell metabolism; influence of nutrition in carcinogenesis.Biophysics-structure and interaction of biopolymers in cells; synthesis of oligo-and polynucleotides of designed structure and sequence; structure and functionof the mammalian genetic apparatus; development of antiviral and chemothera-peutic agents; basic mechanisms of carcinogenesis; cellular and molecularmechanisms of aging. The Department also participates in a University-wideconcerted effort in areas of macromolecular assemblies and interactions forwhich it has received considerable Federal and private support.

Candidates must have an outstanding record of research achievement in any areaof biochemistry, biophysics or molecular biology, whether or not the area iscurrently represented in the Department; and the desire and ability to providestrong leadership to an already excellent, vibrant, growing department in theinterdisciplinary setting of the School of Hygiene and Public Health.Interested persons are encouraged to submit a curriculum vitae to:

Dr. Barry ZirkinChairman of the Biochemistry Search Committee

Division of Reproductive BiologyThe Johns Hopkins School of Hygiene and Public Health

615 North Wolfe StreetBaltimore, MD 21205

The Johns Hopkins University is an Equal Opportunity employer

ASSOCIATE EDITOR NWe're looking for a PhD molecular biologist withphysiological orientation to join Science as aneditor. The successful applicant will be able todemonstrate a broad range of interests andsome experience with biochemical approachesto medical problems. Requirements include atleast two or three years of post-doctoral experi-ence and publications in the refereed literature.Science editors have varied responsibilities inmanuscript selection ranging from editing forclarity to soliciting papers. Previous editorialexperience is not required. This is a full-timeposition in our Washington offices.Please send resume and list of publications withcover letter and salary requirements to:

Mr. Gregory StokesAAAS

1333 H Street, NWWashington, DC 20005

EOE

Research Scientist/ImmunologyFRANCE

ROUSSEL-UCLAF is a major pharmaceutical company involved in Chemistryand Biotechnology for pharmaceutical, veterinary and agricultural activities.The Company is seeking an immunologist for its Biotechnology Department

*............ocated in suburban Paris.,........... The successful candidate will join a multidisciplinary group, and head a team of

and cytokines with immunomodulatory properties.-- ~Requirements include a Ph.D and 2/3 years relevant pst-doctoral : international

experiences would be appreciated. Enthusiasm and communication skills areimportant qualities. A substantial experience in cellular immunology will be

-,,,, ,,.,determinant.

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75007~~~~~PAI (FRANCE).S 0

ROUS'SEL UCLAF $ 0000

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m

Pharmacia P-L Biochemicals

Genetics Institute is a company known for its innovative approachto the scientific research, development and manufacture of humantherapeutic agents. The successful application of a sound businessstrategy in the development of our company enhances our strengthand promising future in biotechnology.

DiscoveryResearch

Several openings exist to join our research group at our Cambridge,MA location. We are looking for candidates with a BS/MS in the bio-logical sciences and a minimum of two years' experience in any ofthe following areas.

Molecular BiologyHistology

Cell BiologyMicrobiology

Interested candidates should forward a resume, in confidence,to Susan Fletcher, Genetics Institute, 87 CambridgePark Drive,Cambridge, MA 01240.We offer a stimulating and dynamic work environment plusan excellent salary and comprehensive benefits package.

An Equal Opportunity Employer, M/F/IIV

Genetics InstItute

ENZYMOLOGLIST,MOLECULARBIOLOGY R&D

Pharmacia P-L Biochemicals is a growing subsidiaryof Pharmacia LKB Biotechnology, a world leader inbiotechnology products. We are strongly committed tothe development of advanced products for molecularbiology research, many based on highly purifiedproteins. We have an immediate opening in our R&Dgroup for an experienced enzymologist. The successfulcandidate should have extensive experience in thepurification of "molecular biology" enzymes, preferablyin a commercial setting. Experience in gene cloningand characterization would be a distinct advantage.

This position will offer you plenty of challenge andopportunity, as well as a competitive salary andbenefits package. For consideration, please sendyour resume with salary history to:

S. Hoist, Administrative AssistantPharmacia P-L Biochemicals2202 N Bartlett AvenueMilwaukee, Wisconsin 53202

We are an equal opportunity employer M/F/HN.

Pharmacia

Research ScientistAnimal Science

Pfizer Central Research has an excellent opportunity fora creative scientist at its modem Animal Health Researchfacility in Terre Haute, Indiana. As a member of theanticoccidial project team, you will have an opportunity toexercise ingenuity and originality in developing andconducting basic and applied research toward the in vivoevaluation of potential anticoccidial agents.We are seeking an accomplished scientist who is innova-tive, enthusiastic, has good communication skills and en-joys working as part of a strong multidisciplinary projectteam. You must possess a PhD in Animal Science -Poultry Science. Postdoctoral experience would be anasset; however, educational training, intellectual capa-bilities and leadership traits are most important.Pfizer provides an outstanding opportunity for profes-sional recognition and career growth. We offer excellentcompensation, comprehensive benefits and relocationassistance. Qualified applicants should submit a currentresume with names of three references to: Ms. ChristinaBatjer, Senior Personnel Supervisor, Pfizer Inc., P.O. Box88, Terre Haute, IN 47808. An equal opportunity em-ployer.

POSTDOCTORALRESEARCHERSThe "Biomolecular Mechanisms" sectionof the Los Alamos National Laboratoryhas openings for postdoctoral fellows.Research conducted in this program in-cludes:

1) Studies on the vertebrate rod, asingle photon detector that canregulate its sensitivity over a widedynamic range. We are examiningthe fine control of those geneproducts which regulate the photon-sensitive membrane current in thisphotoreceptor cell.

2) Studies on the microangiopathy ofdiabetes, a primary cause of humanblindness and renal failure. We areexamining the regulation of sodiumtransport and cell volume in mam-malian erythrocytes and the revers-ible impairment of Na+ transport andred cell swelling found in hyperglyce-mic states.

3) The differential excretion of glycatedand unmodified albumins by themammalian nephron is correlatedwith age. We are examining agerelated changes in the biochemicalcomposition and physical propertiesof selected basement membranestructures.

Applicants should have a strong back-ground in protein chemistry and enzymeregulation, a doctoral degree obtained inthe past three years, and must qualify fora Department of Energy "Q" securityclearance. Postdoctoral appointmentsare for one year, renewable for a secondyear. The salary range is $33,640 -

$35,445 per year. Please send acurriculum vitae to Dr. Mark W. Bitensky,Senior Fellow, ADR, MS D434, LosAlamos National Laboratory, Los Alamos,NM 87545. (505) 667-9420.

To apply formally, send resume, employ-ment application, graduate and under-graduate transcripts, and three lettersof reference to Carol M. Rich, HumanResources Development Division,PD-89-059, Los Alamos NationalLaboratory, Los Alamos, NM 87545.

Affirmative Action/Equal OpportunityEmployer

University of California

EL©0L)\L$ 0Sm$-(~

CardiovascularResearch

G.D. Searle, a worldwide leader in thepharmaceutical industry, has im-mediate openings for the following

laboratory professionals to work in the Depart-ment of Cardiovascular Diseases Research.Successful candidates will participate in basicand applied research programs directed towardthe discovery of novel cardiovascular thera-peutic agents.

PHD PHARMACOLOGIST - Requires 2 or moreyears experience in cardiovascular research withdemonstrated record of scientific achievement.Position requires basic research skills as wellas ability to function on a drug developmentteam. Basic areas of research activities includehypertension, congestive heart failure and renalfailure.

PHD-PHARMACOLOGIST - POST-DOCTORALPOSITION in cardiovascular research. Oppor-tunity to work in environment that combinesbasic research, ranging from molecular biologyto whole animal pharmacology, and teamapproach to drug discovery.

BS/MS BIOCHEMIST - Requires BS/MS inbiochemistry, pharmacology or biology with aminimum of 3 years laboratory experience;previous experience in receptor binding meth-odology is preferred. Experience in several ofthe following areas is desirable; enzyme assays,column chromatography, electrophoresis,immunoassays. Responsibilities will includeinvestigating the receptor binding properties ofnovel compounds in addition to carrying outbiochemical studies aimed at obtaining a greaterunderstanding of receptor-ligand interactions.Good oral and written communication skills arenecessary.

The above positions are available at the St. Louissite of G.D. Searle R&D in the newly built,modern Life Sciences research facility. Thisoffers a unique opportunity to interact with amultidisciplinary team of scientists in a stimu-lating research environment. G.D. Searle &Company, a wholly owned subsidiary of Mon-santo Company, offers competitive salary andbenefits plans. Qualified applicants should sendresumes in confidence to: Joan M. Lineberry -GMO; G.D. Searle & Company; Monsanto LifeSciences Research Center-BB4E; 700 Chester-field Village Parkway; St. Louis, MO 63198. AnEqual Opportunity Employer.

SE4RLE -I

m

m

POSITIONS OPEN

FACULTY POSMIION AVAILABLETHE UNIVERSITY OF PITTSBURGH

DEPARTMENT OF CRYSTALLOGRAPHYApplications are invited for a tenure-stream junior

faculty appointment in the Department of Crvstallogra-phy. The appointee is expected to develop a strong.research program involving methodological or other newcrystallographic approaches to structural problems im-portant m the biological, physicochemical, or materialssciences. Applications, including curriculum vitae and astatement ofresearch interests, should be sent to: Profes-sor B. M. Craven, Department of Crystallography,University of Pittsburh, Pittsburgh, PA 15260. TheUniversity of Pittsburgh is an Equal Opportunity Employer.Applications from women and members of racial minorities areespecially encouraged.

FACULTY POSITIONTUMOR IMMUNOLOGY

The Division of Oncology, Thomas Jefferson Univer-sity, has a tenure-track positon at the ASSISTANT ORASSOCIATE PROFESSOR level available for Sep-tember 1989. Candidates should have a Ph.D. or anM.D. with Board-eligibility in medical oncology, andhave an active researc program in tumor immunologyor tumor antigen immunochemistry. Send curriculumvitae and a brief description of research interests to: Dr.Michael J. Mastrangelo, Division ofMedical Oncolo-gy, Thomas Jefferson University, 1015 WalnutStreet, Suite 1005, Philadelphia, PA 19107. EqualOpportunity Employer.

Medical College Department of Microbiology andImmunology positions available with suitable experienceand background in immunology and/or virology. (i)Tenure-track position for ASSISTANT/ASSOCIATEPROFESSOR, (ii) several positions for research grantsupported RESEARCH ASSISTANT PROFES-SORS and (iii) RESEARCH ASSOCIATES ORPOSTDOCTORAL FELLOWSHIPS. Sehd by 15May 1989 a letter of interest, a current curriculum vitaeand names of at least three references to: Dr. HermanFriedman, Professor and Chairman, Department ofMedical Microbiology and Immunology, Universityof South Florida, College of Medicine, 12901 BruceB. Downs Boulevard, Tampa, FL 33612. According toFlorida law, applications and meetings regarding thesame are open to the public. USF is an AfirmativeAction/Equal Employment Opportunity Employer.

IMAGE ANALYSIS SYSTEMRESEARCH ASSOCIATE

The Department of Physiology, Morehouse School ofMedicine, is seeking a mature individual to manage amulti-user SUN-based Image Analysis facility. Back-ground in cell biology with programming expenence inUNIX is required; in fluorescence microscopy and videotechnology highly desirable; in computer interfacing andnetworking desirable. Salary commensurate with qualifi-cations and experience. Position available immediatelv.Qualified applicants should submit curriculum vitae to:

Dr. Catherine ChewDepartment of Physiology

Morehouse School of Medicine720 Westview Drive, SW

Atlanta, GA 30310Morehouse School of Medicine is an Affirmative Action!

Equal Opportunity Employer.

IMMUNOLOGIST. The Baptist Medical Centers,Department of Research, has an immediate opening foran established investigator with a Ph.D. and/or M.D. andproven funding in a clinically relevant area of immunolo-gy. Areas of research include, but are not limited to,tumor, transplantation, or nutritional immunology, andimmunotherapeutics or diagnostics. The position offersan exciting opportunity for an industrious scientist with abroad knowledge of immunology to establish and directan immunology program blending basic and clinicalresearch in a hospital setting. Salary commensurate withexperience and qualifications. Generous benefits pack-age. Qualified applicants should send curriculum vitaeand names of three references by 1 June 1989 to: DavidA. Otto, Ph.D. c/o The Baptist Medical Centers,Human Resources Departmcnt, P.O. Box 830605,Birmingham, AL 35283-0605. The Baptist MedicalCenters is an Afirmative Action/Equal Opportunity Employer.

POSITIONS OPEN

IN VIVO NMR SPECTROSCOPY. The Depart-ment of Radiology of the University of Iowa, College ofMedicine, invites applications for a position in NMRspectroscopy. The University Hospitalhas a 1.5 T wholebody MR system with spectroscopic capabilities and hasinitiated research aimed towards eventual clinical applica-tion of in vivo MR spectroscopy. The successful candi-date will develop an active research program and collabo-rate with other investigators. A Ph.D. in chemistry,biochemistry, or related field is required. Experiencewith in vivo NMR is preferred. Academic rank commen-surate with experience. Contact: E. A. Franken, Jr.,M.D., Professor and Head, Department of Radiolo-gy, University of Iowa, Iowa City, IA 52242. Womenand members of minority groups are encouraged to apply. TheUniversity ofIowa is an Affirmative Action/Equal OpportunityEmployer.

INSTRUCTOR-The University of Texas South-western Medical Center at Dallas has an opening at levelof instructor. Successful candidates should have Ph.D. inbiochemistry and strong background in chemistry withminimum of 5 years of experience in lipid chemistry andbiochemistry. Preference will be given to candidates withecperience in phospholipid biochemistry and phospho-lipid metabolism. Lipid extraction, thin-layer chroma-tography and capillary gas chromatography are essentialrequirements; familiarity with methods of enzymologyand radioisotope labelling and high pressure liquid chro-matography are also highly desirable. Responsibility willinclude laboratory aspects of a research project dealingwith need for omega-3 fatty acids for normal develop-ment in the human, including fatty acid analysis ofplasma and red blood cell membranes, lipid subclasses.Send curriculum vitae and three letters of reference by 15May 1989 to: Ricardo Uauy, M.D., Ph.D., Depart-ment of Pediatrics, 5323 Harry Hines Boulevard,Dallas, TX 75235-9063. Affirmative Action/Equal Op-portunity Employer.

University seeksINSTRUCTOROF BIOCHEMIS-TRY. Will be responsible for teaching graduate studentsin laboratory techniques and lectures on topography ofpost-translational modifications ofproteins (i.e. glycosvl-ation, phosphorvlation) in the endoplasmic reticulumand Golgi apparatus of higher and lower eukaryotes.Must have research experience in these subjects and beable to conduct independent research in them. Ap-proaches should include biochemistry, cell biology, andgenetics. Ph.D. in biological science is required. Sendletter and curriculum vitae before 15 June 1989 to:Chair, Instructor Search Committee, Department ofBiochemistry, University of Massachusetts MedicalSchool, 55 Lake Avenue North, Worcester, MA01655. Affirmative Action/Equal Opportunity Employer.

JUNIOR FACULTY POSITION available in thepharmacologyv and biochemistry of antineoplastic agentstargeted agaist specific human cancer types. Studies willinvolve the modulation of anticancer agents with thvmi-dylate synthase as the primary target. The focus will beon metabolism of reduced folates, modulation ofreducedfblate pools, and optimization of drug scheduling fortherapeutic gain. Research will also identif* factors thatinfluence the regulation and turnover of thymidylatesynthase in elucidating the importance of the enzyme as atherapeutic target. Candidates should have the Ph.D.degree with a minimum of 3 years of postdoctoralexperience. A strong background in biochemistrv isadvantageous. Send curriculum vitae and names of threereferences to: Dr. J. A. Houghton, Laboratories forDevelopmental Therapeutics, Dcpartment of Phar-macology, St. Jude Children's Research Hospital,332 North Lauderdale, Mcmphis, TN 38101. EqualOpportunity/Affirmative Action Employer.

MANAGER, VIRUS PRODUCTIONAmbico, Inc., a rapidly growing veterinary biotechnol-

ogy company, located just outside Des Moines, Iowa, isseeking a manager for its Virus Production Department.We wi.l consider candidates with a Master's Degree andat least 3 to 5 years of work experience in cell culturemethodology and virology. Responsibilities will alsoinclude certain developmental activities in collaborationwith our research department. This is an excellentgrowth opportunity for the right individual. Please sendreurnu to: Human Resources, Ambico, Inc., Box 522,Dallas Center, IA 50063.

POSITIONS OPEN

MAGNETIC RESONANCE SPECTROSCOPIST.Applications are invited for a non-tenure-track positionas research assistant professor in the Department ofBiochemistry, University of Virginia, Applicants for thisposition must be expert in e theory of magneticresonance spectroscopy and in the application of thesetechniques to lipid bilayers and biological membranes.They must also have extensive experience in the synthesisof phospho- and sphingolipids and other complex mem-brane lipids. The position will require advanced gradu-ate-level teaching of the theory and applications ofmagnetic resonance spectroscopy. Applicants must holda Ph.D. degree and have at least 4 years of postdoctoralresearch experience. Curriculum vitae, copies ofacademictranscripts and three letters of recommendation shouldbe sent to: Professor T. E. Thompson, Department ofBiochemistry, The University ofVirginia, Charlottes-ville, VA 22908. Applications should be postmarked onor before 11 May 1989. Affirmative Action/Equal Opportu-nity Employer.

MOLECULAR BIOLOGIST, a junior level re-search position in our Department of Physiology andMedicine. We are seeking a scientist with research back-ground in molecular biology and an interest in celldifferentiation. Candidates sfiould have a Ph.D., M.D.,or D.V.M. degree with accomplishments that demon-strate the ability to maintain an independent researchprogram. The appointee will complement the currentresearch in neonatal pulmonary disease conducted by Dr.Robert A. deLemos of this institution actd Drs. Rich-ard J. King and Jacqueline J. Coalson of The Universi-ty of Texas Health Science Center at San Antonio. Theprogram focuses on the physiologic and molecular basesof chronic lung disease.The Southwest Foundation for Biomedical Research is

a nonprofit, private research institution with a staff of45scientists and facilities for DNA sequencing, oligonucle-otide and peptide synthesis, hybridomas, electron mi-croscopy, flow cytometry and computer modeling. It alsohas extensive nonhuman primate resources which includebaboons, rhesus monkevs, and chimpanzees.

Interested candidates should mail curriculum vitae,brief summary of research goals, and names and tele-phone numbers of three references to: Personnel Direc-tor (29), Southwest Foundation for Biomedical Re-search, P.O. Box 28147, San Antonio, TX 78284.Equal Opportunity Employer M/F.

The Section of Endocrinology at the VA Hospital ofthe Indiana University Medical Center seeks MOLECU-LAR BIOLOGIST (Ph.D./M.D.) for a position aspostdoctoral fellow, assistant scientist or assistant profes-sor depending upon previous training and experience.Excellent advancement and career opportunities withcompetitive salary. Applicant would interface with scien-tists activelv studying the molecular and cellular biologyof Vitaniun D and insulin hormone action. Please sendresume, letter describing research experience, and twoletters ofrecommendation to: Drs. S. Manolagas and T.Garvey, Section of Endocrinology and Metabolism,VA Mcdical Center (llE), 1481 West 10th Street,Indianapolis, IN 46202.

MOLECULAR BIOLOGY/IMMUNOLOGYPOSTDOCTORAL ASSOCIATE to collaborate on

design and use of molecular labels for antigen-specific Tcells to be used to examine interaction ofT cells withantigen in vitro and in vivo. Available July 1989. Pleasesend curriculum vitae, statement of research interests,and names and telephone numbers ofthree references to:Robert B. Fritz, Ph.D., Dcpartment ofMicrobiology,Medical College of Wisconsin, 8701 WatertownPlank Road, Milwaukee, WI 53226.

MOLECULAR NEUROBIOLOGY AT McMAS-TER UNIVERSITY. The Department of BiomedicalSciences invites applications for TENURE-TRACKPOSITIONS (Ph.D. or M.D.). The existing strengthsof the Department are in nerve growth and regeneration,neurotransmitters and receptors, smooth muscle andvision. ApXlications, together with curriculum vitae andnames andy addresses of three referees, should be sentbefore 30 June 1989 to: Dr. A. J. McComas, Depart-ment of Biomedical Sciences, McMaster University,1200 Main Street West, Hamilton, Ontario, Canada,L8N 3Z5. Preference will be given to Canadian citizens andpermanent residents in Canada.

SCIENCE, VOL. 244380

Public Service Commission Commission de la fonction-' of Canada publique du Canada

,,i''L: Biologists (51-04)Health and Welfare CanadaHealth Protection BranchOttawa, Ontario

The Bureau of Biologics requires two experienced scientific professionals to head two different areaswithin the Bureau.

Bacterial Antigens andAntisera SectionReference number: S-88-31-8119-47JG-G35

As a Biologist with the Bureau, you will direct the activities of this Section. This involves regulatorycontrol testing and evaluation of the safety and efficacy of various bacterial vaccines and antisera,as well as other biological drugs prepared with biotechnology for human use in the prevention andtreatment of diseases. You will also direct and coordinate development research programs on theabove-mentioned drugs.Requirements include graduation with a doctoral degree from a recognized university in a biologicalscience or a lesser degree with evidence of research experience. You must also possess laboratoryand research experience in microbiology, molecular biology and immunology. Knowledge of English isessential.

Immunology SectionReference number: S-89-31-5221-47JG-G35As a Biologist with the Bureau, you will oversee the activities of this section. Such a responsibilityinvolves regulatory control testing and evaluation of the safety and efficacy of various biological drugsIhormones, enzymes, allergenic products) prepared by different production methods including biotechnology.We will rely on you to act as a consultant in the appraisal and evaluation of new drug submissionsand to evaluate operating procedures of Canadian and foreign pharmaceutical manufacturers. You willalso direct and coordinate development research programs on the above-mentioned drugs.Education includes graduation with a doctoral degree from a recognized university in a biologicalscience or a lesser degree with evidence of research experience. You must also possess laboratory andresearch experience in biochemistry and immunology. Experience in molecular biology and microbiologywould be a definite asset. Knowledge of English is essential.

We offer a salary ranging from $48,139 to $55,591 commensurate with your qualifications andexperience.Please forward your resume and/or application form, quoting the appropriate reference number to:Joan Girling, 613) 996-8054, Public Service Commission of Canada, National Capital Region,171 Slater Street, Ottawa, Ontario K1A OM?.

Closing Date: 31 May 1989

C ahIIha dt. Public Service Commission of Canada is an equal opportunity employeri

I2IDAf-ClflV DOCCADI%U DDnfcofnDfUIl EIu

RESEARCH ASSOCIATES wDHtUcIUTncIcnton rnurcoounanir imMOLECULAR BIOLOGY NEURODEGENERATIVE DISEASES

LOCATION:Amgen, an industry leader in advanced biotechnol- McMaster University Faculty of Health Sciences with primary appointment in theogy, develops products for a wide variety of applica- Department of Medicine, Psychiatry, Clinical Epidemiology and Biostatistics, ortions. Recent progress has created an opportunity Biomedical Sciences.for a BS or MS scientist to contribute to on-going RANK: Associate or Full Professorresearch efforts in molecular biology.Qualified applicants should have a BS or MS in QUALIFICATIONS:Molecular Biology, Biochemistry or a related dis- Qualifications for this job will include an MD with subsequent specialtycipline and 2-4 years of experience in Prokaryotic qualifications in psychiatry, internal medicine, clinical pharmacology, or clinicalMolecular Biology or Molecular Genetics. Experi- epidemiology, or completion of a postgraduate degree in a relevant biomedicalence with basic molecular biological techniques science. Under exceptional circumstances, applications from non-MD scientistssuch as library construction, vector construction, will be considered. The successful candidate will be an established independentsuch baslbaryc nsrtn, vectrs investigator with an interest in the investigation and/or treatment of neurodegen-immunoblot analysis and enzyme assays is essen- erative diseases with cognitive impairment. The successful candidate will havetial. Familiarity with Gram positive organisms is an opportunity to work as part of a multi-disciplinary group focused on thehighly desirable. pharmacologic treatment of neurodegenerative diseases, and must have aAmgen offers a stimulating and challenging proven record of success in a multi-disciplinary research programme. Expertiseresearch environment as well as an attractive loca- in the evaluation of methods applied to neuro-cognitive assessment would betion one hour northwest of Los Angeles. Amgen especially valuable.also offers an excellent compensation and benefits SALARY:package. Qualified applicants should send a Salary will be appropriate to experience, rank, and involvement in clinicalresume and a list of 3 references, in confidence, to: activities.

AMGEN, INC. CLOSING DATE: June 30, 1989Recruitment, Dept. #391 Interested applicants should apply in writing, enclosing a curriculum vitae with1900 Oak Terrace Lane the names and addresses of three referees to: DR. STUART M. MacLEOD,Thousand Oaks DEAN, FACULTY OF HEALTH SCIENCES, MCMASTER UNIVERSITY, 1200 MAINCA 91320 STREET WEST, HAMILTON, ONTARIO L8N 3Z5

Opportunity In accordance with immigration requirements, this advertisement is directed toEmpioyer Canadian citizens and permanent residents.

BIOTECHNICAL/RESEARCH OPPORTUNITIES DEaANInterferon Sciences, Inc. is a growing biotechnologycompany located at the heart of the pharmaceutical GRADUATE SCHOOLindustry in central New Jersey. Applications are invited OF BIOMEDICAL SCIENCESat all degree levels for R & D positions in the followingareas: As part of a plan to enhance its effectiveness and impact as

Immunochemistry/Hybridoma a major research center, The University of Medicine and Den-Immunochemist with experience in immunoassay devel- tistry of New Jersey seeks an accomplished Scientist as Deanopment and production and purification of monoclonal of its Graduate School of Biomedical Sciences. The Graduateand polyclonal antibodies (RD101). School consists of 14 departments on two campuses offer-

ing programs leading to the Ph.D., M.D./Ph.D. andProtein Biochemistry D.M.D./Ph.D.

Biochemist with experience in purification and character- The successful candidate will have a Doctoral degree in an ap-ization of proteins, affinity chromatography, and product propriate discipline plus a track record of substantial researchdevelopment (RD1 02). activity sufficient for appointment as a tenured Professor. Ad-

Cell Biology ministrative experience is desirable:Biologist with experience in mammalian cell culture and Review of applications will begin immediately. The Universitycytokine assay development (RD1 03). will continue to accept applications until the position is filled.

Molecular Genetics Applicants should send a complete curriculum vitae and a bnefletter of interest to: Harvey Ozer, M.D., SearchMolecular biologist with experience in cDNA cloning, Committee Chair, Chairman, Department of

and in vitros nutagenesis (RD104)u g e s Microbiologyand MolecularGenetics, UMDNJ-NewJersey Medical School, (S), 185 South Orange

INTERFERON SCIENCES, Avenue, Newark, NJ 07103-2757.V INTERFERON SCIENCES, INC. The UMDNJ is an Affirmative Action/Equal

783 Jersey Avenue Employment Opportunity Employer M/F/HN.

New Brunswick, NJ 08901An Equal Opportunity Employer MIF lU

I I- N EW I ER S EY _

I_The Office of Naval Research, the Air Force Office of Scientific Research, and the Army Research Office are jointly soliciting letters of interestand resumes from qualified candidates to fill liaison scientist positions in their combined office in Tokyo. Candidates are sought who are UScitizens, are currently research scientists or research engineers and who have a Ph.D. or equivalent experience in physical, environmental,engineering, or life sciences. In general, preference is given to candidates from the academic or govenmment sectors. Knowledge of DOD R&Dactivities; relevant, established foreign contacts; and stature in the intemational R&D community are highly desirable features of an applicant'sbackground.

Generally, up to 2-year assignments are available for coverage of the following fields (periods are somewhat negotiable):

Computer Science (continuing requirement)Electro-optics/lasers

Materials/composites/ceramicsChemistry/polymers

BiotechnologySolid State ElectronicsManufacturing ScienceStatistics/Applied Math

Liaison scientists survey research in selected areas of importance to current or potential R&D interests of the sponsoring offices. They interactwith foreign scientists via personal contacts and attendance at meetings and write interpretive reports of their survey efforts.

Candidates should send letters of interest (indicating dates of availability) and resumes to:

Ms. Pearl CanoOffice of Naval Research

International Programs ( Code lilDS)Arlington, Virginia 22217-5000

GA If GLAXO INSTITUTE FOR MOLECULAR BIOLOGY S.A.

The Geneva biotechnology research unit of the largest U.K. pharmaceutical group has a vacancy for a

Biochemistto investigate

membrane receptorssignal transduction mechanisms

The Glaxo Institute for Molecular Biology applies a molecular approach to the discovery of effective newmedicines. Projects include inflammatory diseases, viral therapeutics, neurobiochemistry and theregulation of cell proliferation and differentiation.The Institute has a staff of over 120 people, grouped in small teams of specialists from several domainsof modern biology. We are part of the Glaxo Group, which has an outstanding reputation for the qualityof its research and products. We offer an excellent salary and benefits package, an interactive researchenvironment, and opportunities for career development in one of the most attractive parts of Europe.The ideal candidate will have several years of postdoctoral research experience and a proven trackrecord in the field of membrane receptors or signal transduction mechanisms. Experience with animalcell cutures would be an advantage.If you are interested in this position, please send your curriculum vitae with a list of publications and thenames of three references to: Rita Gloor, Personnel Manager, GLAXO IMB SA, 46, route des Acacias,1211 Geneva 24, Switzerland.

POSITIONS OPEN

MOLECULAR NEUROBIOLOGYNATIONAL INSTITUTE FOR

DRUG ABUSE (NIDA)TENURE-TRACK AND

FELLOWSHIP POSMIIONSThe Addiction Research Center (ARC), NIDA, wish-

es to enhance its programs in molecular neurobiology.Current efforts center on cloning and assessment ofregulated expression of genes relevant to neurotransmis-sion and drug abuse, and solubilization and purificationofdrug receptors. Applicants for postdoctoral fellowshipand tenure-track positions, preferably with expertise inmolecular biologv and/or molecular neurobiology shouldapply to: Dr. George Uhl, Laboratories of MolecularNcurobiology, ARC/NIDA, Box 5180, Baltimore,MD 21224. Federal Government is an Equal OpportunityEmployer.

NEUROBIOLOGIST/NEUROETHOLOGISTCOLORADO STATE UNIVERSITY

Applications and nominations are solicited for aneurobiologist/neuroethologist position at the assistantprofessor level. We seek an individual who is conductingresearch on the cellular and/or molecular basis of behav-ior. Postdoctoral experience is preferred. The tenure-track appointment will be in the biology department, andthe individual will be expected to participate in theUniversitv-wide Program in Neurona Growth and De-velopment. The successful candidate will be expected tomaintain an extramurally funded research program, teachan introductorv course in biologv, and develop a coursein his/her specialtv. Applications should include curricu-lum vitae, selected reprints, brief statement of researchplans and teaching interests, and three letters of recom-mendation. Deadline is 31 Julv 1989. Search mav becontinued if a suitable -candidate is not found. Startingdate: January, or later, 1990. Applications and normina-tions should be sent to: Dr. Phuip N. Lehner, Chair,Search Committee, Departnent ofBiology, ColoradoState University, Fort Collins, CO 80523. CSU is anAfirmative Action/Equal Opportunity Employer. EO Ofice:314 Student Services Building.

NEUROTOXICOLOGY POSTDOCTORAL RE-SEARCH ASSOCIATE POSITION to study xeno-biotic-induced neuronal injunr associated with alter-ations in intracellular ionic homeostasis. Techniques tobe used include intracellular fluorescence probes, cellculture and single cell confocal microscopy. Experiencein biochemical techniques and/or cell culture desired.Starting salary is $20,000 per vear. Send curriculum vitaeand three letters of reference to: Dr. Gary E. Isom,Department of Pharmacology and Toxicology, Pur-due University, West Lafayette, IN 47907. EqualOpportunity/Affirmative Action Employer.

The Department of Pediatrics at the University ofMichigan is seeking Board eligible/certified PEDIAT-RIC HEMATOLOGIST/ONCOLOGISTS. Dutiesinclude patient care, teaching and research activities. TheUniversity of Michigan is an Equal Opportunity/AfirmativeAction Employer. If interested, please send curriculumvitae to: Laurence A. Boxer, M.D., Director, PediatricHematology/Oncology Division, F6515 C. S. MottChildren's HospitaL, 1500 East Medical CenterDrive, Ann Arbor, MI 48109-0238.

PHYSIOLOGIST: Position open for general phvsi-ologist. Primarv responsibilities: not more than 209% oftime teaching medical physiology to medical students,and at least 80% of time for research. Please sendcurriculum vitae detailing teaching experience, researchinterests, grant track record and the names of threereferences to: Dr. Arnold L. Nagler, Associatc Dean,Basic Sciences, New York Collceg of OsteopathicMedicine, Old Westbury, NY 11568. Affirmative Ac-tion/Equal Opportunity Employer.

PLANT MOLECULAR BIOLOGYPostdoctoral position, available June 1989 for muta-

tional analvsis of reglatorv sequences in plant seed-specific genes. A Ph.D. in plant molecular biologybiochemistry, genetics, or with experience in recombi-nant DNA technique preferred. Salarv $24,000 per vear.Send resume to: Dr. Norimoto Murai, Departnent ofPlant Pathology and Crop Physiology, LouisianaState University, Baton Rouge, LA 70803. Tel-phone: 504-388-1380. An Equal Opportunity Employer.

POSITIONS OPEN

PIANT ECOLOGIST. Tenure-track assistant pro-fessor to join active program in ecology and environmen-tal biology. Availabke August 1989. Research area open;wetands ecologist preferred. Responsibilities indudeteaching ecology, botany, and courses in area of special-ty, and maintammg an active research program involvinggraduate students. Ph.D. required; postdoctoral experi-ence preferred. Send curriculum vitae, unofficial tran-scnpts, and names and telephone numbers of at lcastthree refcrences by 29 Ma 1989 to: Dr. Gary Childers,Dqetment ofBlocal Scences, Soudeasten Loui-siam Univeriy, Box 814, Hammond, LA 70402.

POLYMER SCIENCE AND ENGINEERINGUNIVERSITY OF MASSACHUSEITS

Applications and nominations are invited for a tenure-track faculty appointment at the ASSISTANT PRO-FESSOR level in the Department of Polymer Scienceand Engineering to begin September 1989. Candidatesmust have an eamed doctorate and a strong comrnitmnentto research and teaching excellence. Salary commensuratewith qualifications and experience. Applicants shouldsubmit curriculum vitae and an outline of research plans,and arrange for three letters of reference to be sent to:Professor Frank E. Karasz, Search Committee Chair-man, Departmcnt of Polymer Science and Engineer-ing, Umversity of Massachusetts, Amherst, MA01003. Closing date 15 May 1989. The University ofMassachusetts is an Affirmative Action/Equal OpportunityEmployer.

UNIVERSITY OF MINNESOTADEPARTMENT OF PHARMACOLOGY

POSTDOCTORAL ANDRESEARCH ASSOCIATE POSITIONS

The Department of Pharmacology, Universitv of Min-nesota Medical School, has postdoctoral and researchassociate positions available in several fields. Our facultvmembers are well-funded and direct strong interdisci-plinary research programs.

Positions are open to applicants upon receipt of aPh.D. degree.

Areas of emphasis include:Molecular biology, biochemistrv, immunology, and

neurobiology-neurochemistryMolecular doning, opioid receptor, receptor, and

chemical biochemistryIntracellular clectrophysiology, ion channelsDru abuse, neuropharmacologyBiochemical/molecular pharmacologyCancer chemotherapy, ummunopharmacologv, drug

metabolism, enzymologv, and anti-viral drugsInterested applicants should send curriculum vitae,

statement of research interests, and the names of threereferences to: Dr. Horace H. Loh, Professor andHead, Department of Pharmacology, 3-249 MillardHall, 435 Delaware Street SE, Minneapolis, MN55455.

The University of Minnesota is an Equal OpportunityEducator and Employer, and specifically invites and encouragesapplicationsfrom women and minorities.

POSTDOCTORAL ASSOCIATEPostdoctoral associate to research cellular and molecu-

lar mechanisms of cookability loss in legume seeds duringstorage. Eamned Ph.D. degree in a field related to thebiochemistry of plant cells and experience in biopolymerisolation/characerization (e.g. HPLC, IF, PAGE) and inSEM techniques necessarv. Send resume, transcripts, andthree letters of recommendation to: Dr. R. DixonPhillips, Department of Food Science and Technolo-

ty of Georgia Agricultural ExperimentStation, Griffin, GA 30223-1797. Deadline for receiptof application is 15 June 1989. The University ofGeorgia isan Affirmative Action/Equal Opportunity Employer.

POSTDOCTORAL FELLOW/RESEARCH AS-SOCIATE POSMIION. Brigham and Women's Hospi-tal, Harvard Medical School seek Ph.D., M.D. or M.D.,Ph.D. candidate for current position with potential foradvancement. Ongoing projects involve the molecularbasis for the regulation of expression of hvpothalamicand adrenal genes by steroids and second messengersystems. Send curriculum vitae, letter of interest andreferences to: Gail Adler, M.D., Ph.D., Endocrinol-ogy-Hypertension Division, 221 Longwood Avenue,Boston, MA 02115.

POSITIONS OPEN

POSTDOCTORAL ANDRESEARCH ASSOCIATE POSITIONSMOLECULAR VIROLOGY/BIOLOGY

Postdoctoral and research associate positions are avail-able (beginning Summer 1989) to participate in ongoingresearch on the molecular biology, virology, and patho-genesis of the simian and feline immunodeficiency virus-es (SIV and FIV). The applicant would be a member ofan NIH-funded multidisciplinary group developing ani-mal models for AIDS. Newlv constructed laboratorvspace (including BL-3 facilities) is available and isequipped with state-of-the-art instrumentation (includ-ing DNA synthesizer, automated DNA sequencer, PCRcycler, etc.). Applicants should possess a Ph.D., M.D., orD.V.M. degree and have demonstrated skills in basicmolecular biologv techniques. Salarv will be commensu-rate with experience and expertise. tnterested candidatesshould send currculum vitae and the names of threereferences to:

Dr. Philip R. JohnsonDivision of Molecular Virology and Immunology

Department of MicrobiologyGeorgetown University School of Medicine

NIHITwinbrook II12441 Parklawn DriveRockville, MD 20852

Georgetown University is an Equal OpportunitylAfirmative Action Employer.

POSTDOCTORAL ASSOCIATE position(s) avail-able in a neuroscience laboratorv which studies neuro-transmitter release due to pain and analgesia, especiallywith respect to substance P and excitatoryv amino acids.Experience doing HPLC, receptor binding or in vivomicrodialvsis is desirable. Ph.D. in biological sciencesrequired. Send curriculum vitae bv 15 Mav 1989 to:Ahce A. Larson, Ph.D., Department of VeterinaryBiology, University of Minnesota, 1988 Fitch Ave-nue, St. Paul, MN 55108. The University ofMinnesota isan Equal Opportunity Educator and Employer and spec/iJcallyinvites and encourages applications from womett and tniorities.

POSTDOCTORAL FELLOW. Department of Mi-crobiology and Immunology, Stanford University, Stan-ford, California. Position available immediatelv to studvhuman papillomavirus gene expression in human cervicaltissues and in cultivated mammalian cells. Previous expe-rience with these or related viral agents and a doctoratedegree (M.D. or Ph.D.) is required. Support is for 2 to 3years. Please send curriculum vitae, bibliography, and thenames and addresses of three references to: Dr. JoelPalefsky, c/o Dr. Gary K. Schoolnik, Howard HughcsMcdical Institute, Beckman Center, Room 241A,Stanford University School of Medicine, Stanford,CA 94305-5425.

TWO POSTDOCTORAL FELLOWSRESEARCH ASSOCIATES

GEORGETOWN UNIVERSITY,WASHINGTON, D.C.

Two positions are available in well-funded laboratoryto study the structure and function of complementproteins and of antibody immunoconjugates. One posi-tion requires background in carbohydrate or glycopro-tein chemistry, the other position in protein chemistryand/or tissue culture. Applicants with prior experiencemav obtain research facultv appointment. Salarv is com-petitive. Positions are available immediatelv. Please sendcurriculum vitae to: Dr. Carl-Wilhelm Vogel, Depart-mcnt of Biochemistry, Georgetown UniversitySchool of Medicine, 3900 Reservoir Road, N.W.,Washington, DC 20007. Georgetown Untiversity is anEqual Opportunity/Afirtnative Action Employer.

POSTDOCTORAL FELLOWSHIP-Individualwill initiate studies of anticancer agents in patients,animals, and in vitro models in research-orientednetworked computerized clinical chemistrv laboratorv.Position involves interaction with phvsicians/scientists inmajor research programs and extensive core facilities.Expected to participate in design and execution ofclinicalprotocols and experiments, publish and present results,and train in chnical chemistry. Send curriculum vitae to:Marshall Goren, M.D., St. Jude Children's ResearchHospital, P.O. Box 318, Memphis, TN 38101. Tele-phone: 901-522-0367. Equal Opportunity Employ-er/Affirmative Aaion Employer.

SCIENCE, VOL. 244384

A RESEARCH FOUNDATION AFFILlATED TO THEUNIVERSITY OF BERGEN

DIRECTOR, INTERNATIONAL CENTREFOR BIRTH DEFECTS

The International Clearinghouse for Birth DefectsMonitoring Systems, affiliated with WHO as a non-governmental organization, the Naflonal Instituteof Public Health, Norway, and the University ofBergen Norway are establishing an InternationalCentre for Birth Defects, to be located at theUniversity of Bergen. Funding for an initial threeyears period is provided by the Norwegian gov-ernment. The purpose of the Centre is- to co-ordinate the surveillance activities of theClearinghouse' including the definition and im-plementation of criteria, standards and methods

- to promote, co-ordinate and undertake collab-orative research among the Clearnghouse mem-ber programmes, and

-to develop and conduct training programmesfor the staff of the member programmes.

The Director reports to the Board, consisting ofrepresentatives of the founding parties. The Direc-tor organizes, conducts and supervises all activi-ftes and functions of the Centre.

High scientific epidemiological qualifications arerequired, and preference will be given to appli-cants with experience in the clinical and epide-miological aspects of birth defects. Ability to workeffectively in a collaborative environment is es-sential. Skill in written and oral communication inthe English language is necessary.

Salary commensurate with training and experi-ence. A faculty position at the University of Bergenmay be established.

The position will be extended beyond the threeyears period provided an extended or perma-nent funding of the Centre.

Further information may be obtained from Profes-sor Lorentz M Irgens, Medical Birth Registry ofNorway, The Armauer Hansen Building, MFH, Hau-keland Hospital, N-5021 Bergen Norway, tele-phone 5 974667.

Letters of application including curriculum vi-tae, and bibliography, should be sent to theFaculty of Medicine, University of Bergen N-5027Bergen Norway, from where a further writtendescription of the post may be obtained, withinMay 5th, 1989.

ResearchScientists

Triton Biosciences Inc., a subsidiary of ShellOil Company located in the San FranciscoBay Area, is a fully integrated pharmaceuticaland diagnostics company focused on productdevelopment opportunities in the areas ofcancer, AIDS and other serious diseases.We currently have the following openings.

BioassayExperienced researcher to develop sensitivebioassays for proteins in support of processand product development activities and finalproduct release. You should have a PhD inBiochemistry, Microbiology or Immunologyand 3 or more years of experience with assaydevelopment, including direct experience inreceptor binding, growth inhibition, antivirals,enzymes and bioassays. Reply to Job #89008.

Molecular ImmunologyYou should have a PhD in Immunology or Bio-chemistry with experience in the immunologi-cal and molecular characterization of proteinantigens. Background in tumor markers,cancer immunology and immunoassaydevelopment required. Reply to Job #RW.

New Cancer MarkersYou should have a PhD in Biological Scienceswith equivalent expertise in cancer biology.Duties include effective interaction withmultidisciplinary team in evaluating newcancer markers for diagnostic use. Reply toJob #YT.Research AssociateHybridoma DevelopmentYou will perform monoclonal antibody re-search and development for cancer, diag-nostics. Your qualifications should include aBS/MS and experience in all aspects ofhybridoma generation and characterization.Reply to Job #RW2.

Triton offers competitive salaries and bene-fits, including relocation assistance. For con-sideration, send your resume with coverletter highlighting your qualifications andincluding the names of three references toTriton Biosciences Inc., 1501 Harbor BayParkway, Alameda, CA 94501. EEO/AAemployer.

Triton Biosciences Inc.

Molecular BiologistCIBA-GEIGY's Agricultural Division has an excellent opportunityfor a Molecular Biologist to contribute to our genetic engineer-ing and crop improvement program. Long recognized as one ofthe world's foremost producers of crop protection chemicals, wehave made a major commitment to Biotechnology research at ourfacility in Research Triangle Park, NC.The Senior Scientist we seek will design eukaryotic gene expres-sion systems for the production of foreign proteins. Qualified can-didates will have a PhD plus two years of postdoctoral experience.Training should be in the area of Molecular Biology or a relateddiscipline, specializing in foreign gene and protein expression.Experience with yeast and/or insect cell systems is also required.You will find that our career support and advancement oppor-tunities are exceptional. CIBA-GEIGY provides a competitivesalary and generous company-paid benefits, including reloca-tion assistance. Please forward your resume, including three let-ters of professional reference, in confidence to: Dr. Mary-DellChilton, CIBA-GEIGY Corporation, Agricultural Division,P.O. Box 12257, Research Triangle Park, NC 27717. We AreAn Equal Opportunity Employer M/F/H/V.

Science Serving Mankind

T CIBA-GEIGYOUR WORLDWIDE INFLUENCE

STARTS WITH ADVANCED RESEARCH

G.D. Searle is recognized worldwide for innovative science andrespected products. Research is a top priority in our ongoing

commitment to increased growth and industry influence. We now offertwo exceptional opportunities to support our dedication to a leadershiprole in Gastrointestinal Drug Discovery.

SR. RESEARCHINVESTIGATOR/IMMUNOLOGY

An immunopharmacologist to develop innovative new approaches totreating inflammatory bowel diseases (IBD). Duties include the utilizationof animal models of I B D and in vitro assays to develop drugs for mucosalanti-inflammatory activity. The successful candidate will hold a PhD in im-munology, biochemistry or pharmacology with at least 2 years post-doctoral experience.

SR. RESEARCH INVESTIGATOR/MOTILITYAn individual to characterize gastrointestinal smooth muscle function invitro, utilizing contraction models and methods of pharmacologic receptoranalysis. Other responsibilities include integrating biochemistry of smoothmuscle into function at the tissue level. Requirements include a PhD inphysiology or pharmacology with at least 2 years of postdoctoral ex-perience in gastrointestinal motility or a related area.We offer an outstanding professional environment and highly com-petitive compensation, including generous benefits. For confidentialconsideration, please forward your resume to: G.D. Searle & Co.,Human Resources Dept. HY1 1, 4901 Searle Parkway, Skokie, IL60077. Equal Opportunity Employer M/F.

SE4RLE=

NUTRITIONAL EPIDEMIOLOGISTPOSITION OPEN IN THE DIVISION

OF EPIDEMIOLOGYAMERICAN HEALTH FOUNDATION

The American Health Foundation is seeking aNutritional Epidemiologist with an interest inresearch on chronic diseases, especially can-cer. The research will involve extensive col-laboration with a multidisciplinary team, in-cluding clinical nutritionists, biochemists, epi-demiologists, and bio-statisticians. Thesuccessful candidate will have:1) An earned Doctoral degree in Nutrition orNutritional Biochemistry and a Masters degreein Epidemiology, or a combination of othercredentials indicative of expertise in both Nu-trition and Epidemiology;2) Publications in the fields of NutritionalEpidemiology;3) A record of accomplishment in writinggrant applications for peer review;4) Experience in designing, planning, execut-ing, and analyzing epidemiological researchprojects.Interested applicants should apply by sendinga covering letter, including salary require-ments, and CV to:

Division of EpidemiologyAmerican Health Foundation

320 East 43 StreetNew York, New York 10017

Equal Opportunity Employer- M/F/HN.

MOLECULAR GENETICISTLADY DAVIS INSTITUTEFOR MEDICAL RESEARCH

The Lady Davis Institute, a researchdepartment of the Sir Mortimer B.Davis-Jewish General Hospital (aMcGill University teaching hospital),is seeking a molecular geneticist atthe assistanVassociate professorlevel. Applicants should hold Ph.D.and/or M.D. degree(s), have signifi-cant post-doctoral experience andthe potential for developing a vigor-ous independent research programon gene expression at a locus in-volved in human disease. Prefer-ence will be given to candidates withM.D. degrees who are qualified andwilling to spend 20% of their time inthe Division of Genetics of the De-partment of Medicine.Send curriculum vitae, statement ofresearch goals and the names ofthree references to:

Dr. Herbert M. Schulman,Actin0 Director

Lady Davis Institute forMedic3l Resesirch

Sir Mortimer B. Davis-JewishGeneral Hospital

Montreal, Quebec, Canada H3T IE2

DEPARTMENT OF PSYCHIATRY

1._ hmlWe are currently seeking a staffscieritist to join our immunolo-gy group. This position requiresa Ph.D. in Immunology with es-tablished expertise in the areasof Immunochemistry, immuneresponse and/or Cytokine func-tional analysis. The successfulcandidate must communicateeffectively and interact exten-sively with scientists from alldisciplines including moleculargenetics, protein biochemistryand mammalian cell culture.This highly interactive and visi-b le position requires strong or-ganizational skills.We offer a stimulating and dy-namic work environment in ad-dition to an excellent salary andcomprehensive benefitsprogram.Interested candidates shouldforward a resume, in confi-dence, to: Sher Rist, GeneticsInstitute, 87 CambridgeParkDrive, Cambridge, MA 02140.An Equal Opportunity Employer M/F/HN

Genetics Institute

I~~~~~~~~

The Sterling Research Group, the worldwide phar-maceutical research and development organizationof Sterling Drug Inc., announces an opening for aSenior Research Biologist in the PharmacologyDepartment at its Rensselaer, New York facility.

MOLECULARPHARMACOLOGIST

Committed ToScientificExcellence

An excellent opportunity exists for a molecularpharmacologist who has expertise in growth factor,ion channel or neurotransmitter receptor bindingstudies to participate in an interdisciplinary approachto basic research and drug discovery. The successfulcandidate should have a doctoral degree in phar-macology, biochemistry or related discipline and atleast two years of relevant post-doctoral training. Ex-perience in cell and tissue culture methodologieswould also be desirable.Sterling Drug Inc. offers competitive salaries and acomprehensive benefits program, along withoutstanding career opportunities for personal andprofessional growth. For confidential consideration,please forward your resume with salary history/re-quirements to:

Jo Ann FitzgeraldEmployee Relations Administrator

STERLINGRESEARCH GROUPA Division of Sterling Drug Inc.81 Columbia TurnpikeRensselaer, NY 12144A Subsidiary of theEASTMAN KODAK COMPANYEqual Opportunity Employer M/F/H/V

A unique position is available immediately for a 1-2 year postdoctoralposition, which offers an opportunity to gain experience in a highlycompetitive pharmaceutical research environment. The ideal candidatewill have extensive background in solid and/or solution phase peptidesynthesis and a strong knowledge of modern synthetic organic chemistry.The successful candidate will work on molecular modelling and syn-thesis of replacements for endogenous vasopressor peptides. Stimulatingcollaboration with biologists and chemists with international scientificreputations is a hallmark of this opportunity. Development and publica-tion of original ideas will be strongly encouraged.Berlex Laboratories, located in northern New Jersey, is a wholly ownedsubsidiary of a major international pharmaceutical company and offersa competitive salary and benefit package. Our location encouragescontacts in the greater New York City scientific community.Interested scientists should send a resume and brief statement ofcareer goals and research interests to: Joan Bianchini, HumanResource Representative, R&D, BERLEX LABORATORIES, INC.,110 East Hanover Avenue, Cedar Knolls, N.J. 07927. Equal opportunityemployer M/W/H/V

UNIVERSITY OF TORONTOApplications are invited for the position of Assist-ant Professor in the area of Molecular Neurogene-tics as applied to psychiatric disorders. Thisposition requires a Ph.D. or other doctoral degreeand significant post-doctoral experience in molec-ular genetics, molecular neurobiology or anequivalent field. The successful candidate will beexpected to work collaboratively with a multidis-ciplinary neuroscience/neuropsychiatric researchgroup comprised of basic and clinical researchersinvestigating the neurobiology and neurogeneticsof psychiatric disorders. The position requiresdemonstrated ability to conduct independent re-search within a collaborative group and to com-pete for extramural funding.The position is tenure track equivalent supportedinitially by the l'Anson fund. Salary is commensu-rate with rank and experience. The position alsoincludes a one time start up research grant.The University encourages both men and womento apply for positions. In accordance with Canadi-an immigration requirements, this advertisementis directed to Canadian citizens and permanentresidents of Canada.Candidates should submit a letter of application, acurriculum vitae and the names of three refereesfrom whom letters of recommendation may besolicited. Please submit responses to: Dr. Jerry J.Warsh, Director of Research, Clarke Institute ofPsychiatry, 250 College Street, Toronto, Ontario,Canada M5T 1 R8.The successful candidate would be expected totake up the appointment prior to September 1,1989.Closing date for applications is May 19, 1989.

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Agoommomb.,

POSITIONS OPEN

POSTDOCTORAL FELLOWSHIPNIH Staff Fellow/Senior Staff Fellow position is avail-

able at the National Institute on Alcohol Abuse andAlcoholism (NIAAA), for studies of neurotransmitterand hormone receptors and their interactions with cyto-kines and growth factors. Preference is given to appli-cants with experience in molecular biology, protein,purification and receptor biochemistry/pharmacology.Salary is commensurate with experience. Only U.S.citizens or permnanent residents are eligible for this position.Send curriculum vitae and name ofthree references to:

Dr. George Kunos, Laboratory of Physiologic andPharmacologic Studies, NIAAA, 12501 WashingtonAvenue, Rockville, MD 20852. Telephone: 301-443-1234. NIAAA is an Equal Opportunity Employer.

POSTDOCTORALMOLECULAR IMMUNOLOGISTS

Two postdoctoral positions are available in an activeprogram of Transplantation Immunology. One individ-ual will conduct studies on immunological unresponsive-ness induction in transplant recipients using either puri-fied soluble HLA molecules, synthesized peptides, orrecipient cells transfected with donor MHC genes. Thesecond individual will study the regulation of expressionof HLA genes.

Salary is commensurate with experience and begins at$23,196.Send curriculum vitae and names of three references to

Marvin R. Garovoy, M.D., Immunogenetics andTransplantation Laboratory, University ofCalifornia,513 Parassus Avenue, Health Sciences East, Room520, San Francisco, CA 94143.

The University ofCalifomia is an Affirmative Action/EqualOpportunity Employer.

POSTDOCTORAL OPPORTUNITY: A challeng-ing opportunity to study the molecular basis of visualdisorders using x-ray crystallography, nuclear magneticresonance (NMR), magnetic resonance imaging (MRI),and/or light scattering. Applicants with experience inphysical chemistry, physics, biophysics, or engineeringshould send a resume and the names of three refer-ences to: Maria Courogen, Department of Biostruc-ture, SM-20, University of Washington School ofMedicine, Seattle, WA 98195. Salary dependent onqualifications.

POSTDOCTORAL POSMONWe are seeking an experienced membrane biochemist

who will isolate the complete bacterial flagellar motorand determine its structure by electron microscopy. TheStructural Biology Laboratory at Brandeis has extensivefacilities for electron microscopy and image analysis andwill provide as part of this project traming in thesetechniques. Inquiries and applications, including curricu-lum vitae and names of three references, should be sentto:

Dr. David DeRosierRosenstiel Basic Medical Sciences Research Center

Brandeis UniversityP.O. Box 9110

Waltham, MA 02254-9110An Equal Opportunity/Affirmative Action Employer.

POSTDOCTORAL POSMON available immedi-ately. Study the regulation of neurotransmitter release inthe CNS. Funded at $18,000 to $22,000 for up to 3years. Send curriculum vitae and names of three refer-ences to: Joseph Masserano, Ph.D., Department ofPharmacology, (C236), UCHSC, 4200 East 9th Ave-nue, Denver, CO 80262.

POSTDOCTORAL POSMON available. Neuro-chemist needed to study the regulation of the enzymetyrosine hydroxylase in pheochromocytoma cells, bovinechromaffin cells and the rat central nervous system.Preference will be given to candidates with a strongbackground in biochemistry. Send curriculum vitae andthe names of three references to: Norman Weiner,M.D., Department ofPharmacology, Box C236, Uni-versity of Colorado Health Sciences Center, 4200East Ninth Avenue, Denver, CO 80262.

POSITIONS OPEN

POSTDOCTORAL POSITION open for studyinglong-term functioning of identifiable adult neurons andthe behaviors the neurons mediate. Studies include be-havior and its physiological and biochemical substrates.A multidisciplinary center on aging provides addedresources. Competitive stipend is provided for 3 vears.Send r6sume and names of three references to: Dr. BertPeretz, DeparentofPhysiology, University ofKen-tucky Medical Center, ILxington, KY 40536-0084.

POSTDOCTORAL POSITION available to studvDNA photolyase and the mechanism of enzymic photo-repair ofDNA damaged by ultraviolet light. Send curric-ulum vitae and names of three references to: Dr. M.Jorns, Department of Biochemistry, HahnemannUniversity, Broad and Vine, Philadelphia, PA 19102.

POSTDOCTORAL position available for M.D. orPh.D. with experience in molecular biology beginningsummer of 1989 to study the molecular mechanismscontrolling feeding behavior. Approaches being takeninclude a molecular analysis ofneuropeptide genes whichaffect feeding as well as a "reverse genetics" approach toclone mutant mouse genes which affect feedingbehavior.

Please send curriculum vitae, summarv ofresearch, andnames of three references to: Dr. Jeffrey M. Friedman,Howard Hughes Medical Institute, The RockefellerUniversity, 1230 York Avenue, New York, NY10021. An Equal Opportunity Employer.

POSTDOCTORAL POSITION available immedi-ately to study the modulation of epithelial chloridechannels using optical as well as electrophysiologicaltechniques. Applicant should have a Ph.D. with a back-ground in transport or electrophysiology desirable. Sala-ry: $30,000 for the first year. Applications includingcurriculum vitae should be sent to: Dr. Deborah J.Nelson, The University of Chicago, Departennt ofMedicine, Hospital Box 249, 5841 South MarylandAvenue, Chicago, IL 60637. An Equal OpportunityEmployer.

POSTDOCTORAL POSMON available 1 July1989 to study the regulation of swarmer ccll differentia-tion in Proteus mirabilis. Ph.D. in microbiology, molecularbiology or biochemistry required. A strong backgroundin recombinant DNA teehnlo preferred. Closingdate for applications is 30 June 1989. Send curriculumvitae and the names of three references to: Dr. RobertBelas, Center ofMarine Biotechnology, University ofMaryland Systms, 600 East Lombard Strect, Balti-more, MD 21202. Equal Opportunity/Affirmative ActionEmployer.

POSTDOCTORAL POSITIONS available imme-diately to study molecular and cellular mechanisms con-trolling parietal cell HCI secretion. Projects require expe-rience in (i) cell culture/protein isolation/purification or(ii) computer-based video image analysis/epifluorescencetechniques. Salaries competitive. Reply to: Catherine S.Chew, Ph.D., Department of Physiology, MorehouseSchool of Mcdicne, 720 Westview Drive SW, Atlan-ta, GA 30310.

Morehouse School ofMedicine is an Equal Opportunity/Affirmative Aaion Employer.

POSTDOCTORAL POSITIONS IN IMMU-NOLOGY, MOLECULAR BIOLOGY, AND VI-ROLOGY. Several are available in multidisciplinary ex-perimental studies utilizing anti-idiotypic antibodies toexamine the molecular basis of idiotype networks in-duced during viral infections. The viral systems to bestudied include hepatitis B virus, human immunodefi-ciency virus (HIV), simian immunodeficiency virus andsimian virus 40. In addition, positions are also availableto examine the use of anti-idiotypes to mimic varioustoxic substances and in cellular immunology aspects ofHIV and SIV infection. These studies will be performedin the laboratories of Drs. Ronald C. Kennedy andTran C. Chanh. Annual postdoctoral salaries range from$21,070 to $29,266, dependent upon prior relevantpostdoctoral experience. Applicants must have a Ph.D.or M.D. degree or expect to obtain one by the end of1989. Send curriculum vitae, and names, addresses andtelephone numbers of at least three references to: Per-sonnel Director (23), Southwest Foundation for Bio-medical Research, P.O. Box 28147, San Antonio, TX78284. Equal Opportunity Employer M/F.

POSITIONS OPEN

POSTDOCTORALPOSMONS availabk to studymutagenesis and the replication of damaged DNA in E.coli and yeast. Current work indudes molecular analysisof yeast genes concemed with mutagenesis (such asREV3, which encodes a nonessential DNA polymerase)and experiments with vectors carrying a single definedlesion. Applicants should have, or expect soon to receive,a Ph.D., and preferably some experience in molecularbiology. Send curriculum vitae and names of threereferences to: Dr. C. W. Lawrence, Deprment ofBiophysics, Univerrsity of Rochcster Medical Center,Rochester, NY 14642. Telephone: 716-275-2948.The University ofRochester is an Equal Opportunity/Affirma-tive Action Employer.

POSTDOCTORAL POSMIIONS IN MOLECU-LAR NEUROBIOLOGY for individuals interested inan interdisciplinary approach to the study of receptor-operated ion channels, with emphasis on GABAA andexcitatory amino acid receptors. Techniques include mo-kcular biology, radioligand binding, photoaffinitv label-ing, ligand-stimulated ion flux, monoclonal antibodies,patch-clamp electrophysiology, and fluorescence digitalimage analysis. Salary $22,000 to $30,000. Send curricu-lum vitae to: Dr. David Farb, Department ofAnatomyand Cell Biology, SUNY Health Science Center, 450Clarkson Avenue, Brooklyn, NY 11203. Equal Oppor-tunity/Affirmative Action Employer.

TWO POSTDOCTORAL POSITIONS are avail-able to study the metabolic and molecular biologicalchanges in legume plants with enhanced nitrogen fixa-tion and altered ammonia assimilation [Science 241, 951(1988)]. These plants have imnpaired glutamine synthe-tase in their roots and nodules, yet they have increased Nassimilation and specific activity and protein concentra-tion of nitrogenase. Motivated individuals with researchexperience in either plant physiology, molecular biologyor biochemistry are sought. Research approach is anintegration of molecular biology and biochemistry/phy-siology and offers an excellent opportunity to developpersonal initiatives. Ample travel funds are available andlaboratory facilities are excellent. Salary $20,000 to$32,000, depending upon qualifications. Send curricu-lum vitae and letters of recommendation to either Dr.Pat J. Unkefer, Mail Stop C345, Los Alamos Nation-al Laboratory, Los Alamos, NM 87545, Telephone:505-665-2556, or to: Dr. Champa Sengupta-Gopa-Ian, Plant Genetic Engineering Laboratory, NewMexico State University, Las Cruces, NM 88003.Telephone: 505-846-5784. To apply formally, sendresume, employment application, undergraduate andgraduate transcripts, and three letters of reference to:Carol Rich, Human Resources Development Divi-sion PD-89-061, Los Alamos National Laboratory,Los Alamos, NM 87545. Affirmative Action/Equal Op-portunity Employer.

POSTDOCTORAL POSITIONS (TWO)-Avail-able for studies of (i) signal transduction and calcium-dependent second messenger function in liver and/orneurosecretory cells and (ii) mechanisms of cocaine andalcohol interaction with excitation-contraction couplingin cardiac muscle. These research projects will utilze arange of recently developed techniques, including high-speed digital imaging fluorescence microscopy and con-focal laser scanning microscopy. The laboratory is wellfunded and brings together a number of researchers inareas of biochemistry, biophvsics and physiology in aninterdisciplinary approach. Pnror experience in one ofthefollowing areas would be an advantage: inositol lipidmetabolism, intracellular calcium homeostasis, cardiacphysiology. Send curriculum vitae and names of threereferences to: Dr. Andrew P. Thomas, 271 JeffersonAlumni Hall, Thomas Jefferson University, Philadel-phia, PA 19107. Equal Opportunity Employer.

POSTDOCTORAIARESEARCH ASSOCIATE:A Duke University and EPA cooperative study will useoxygen-18 labeling techniques to investigate tissue oxi-dation during exposures to ozone and other inhaledpollutants. Expenence with oxidative or free radicalchemistry and familiarity with instrumentation is pre-ferred. Interested individuals should send curriculumvitae to: Dr. Gary Hatch, Chief, Biochemical Toxicol-ogy Section, MD-82, U.S. EPA, Research TrianglePark, NC 27711. Affirmative Action/Equal OpportunityEmployer.

SCIENCE, VOL. 244388

fSuccessf epligen Corporation

is a leader in theapplication of

Biotechnology to the healthcare market. We are cur-rently developing an AIDSvaccine, AIDS therapeuticand diagnostic products,cancer therapies, andnovel bioprocess reagents.We take pride in the highcaliber of our scientificstaff and our collaborationswith major research insti-tutions and corporatepartners in Europe and theUnited States. The expan-sion of our effort hascreated the followingopportunity:

Research ScientistCell BiologyThis scientist will direct the tissue cultureand cell biology laboratory expressingrecombinant proteins in eukaryotic cells.Responsibilities will include directingresearch using cell-based assays to examineprotein structure and function, and coor-dinating mammalian and insect cell culture.A Ph.D. is required, with a history ofresearch which applies protein chemistryor molecular biology training to cellbiology questions. Experience in studyingcell surface proteins is a plus.Repligen Corporation offers a competitivesalary and excellent benefits and equityparticipation. Please submit a cover letter,resume, and references to: BarbaraFleming, Recruiter, Repligen Corporation,One Kendall Square, Bldg. 700,Cambridge, MA 02139. An Equal Oppor-tunity Employer.

RepliGen|110;'0'''t'0 fffff"'-fft t'V t''"''' ''' ''' '"'f''-'''''" ''' ""'''''''''. '"'''. ''''''-''-

MA9NAGER,ANIMAL PHYSIOLOGYCollagen Corporation, a dynamic and growing biotech-

nology company dedicated to expanding its research, develop-ment, production and marketing of differentiated biomedicalproducts, has an immediate opportunity for a Manager ofAnimal Physiology.

In this critical position, you will assume a leadershiprole, supervising the personnel and directing the activities ofour animal facility. In addition, you will provide support toand be an active participant in all research programs and im-plement the policies of the Institutional Animal Care and UseCommittee (IACUC).

The successful candidate will have the following qualifica-tions: DVM degree and at least 5 years' experience in the careand husbandry of laboratory animals, AALAS certification,familiarity with USDA and NIH animal care guidelines, ex-cellent communication and interpersonal skills, and the abilityto manage a variety of projects simultaneously. Supervisoryexperience is essential. Experience in orthopedic research andanimal modeling is desirable but not essential.

At Collagen, we offer opportunities for career growth anddevelopment in a stimulating environment, in addition to anattractive salary and full benefits. For immediate consideration,please send your resume with references, to: S. Hansen,Human Resources, Collagen Corporation, 2500 Faber Place,Palo Alto, CA 94303. We are an equal opportunity employer.

COLLAGENC O R P 0 R A T I O N

N14

UIcCollege of Medicine at Peoria

Senior Research Specialist.A non-tenure track position available immediately to studynoradrenergic seizure regulation in the Genetically Epilepsy-Prone Rat (GEPR). Experience in neuroanatomy, histology,intracerebrodialysis, HPLC with electrochemical detection,stereotaxic placement of cannulae within the brain and evalua-tion of seizures is necessary. The candidate should have someexpertise in utilization of computers in a research laboratory. APh.D. degree in neuroanatomy, neurophysiology or neurophar-macology is required.

Postdoctoral Research AssociatesPositions now available to study noradrenergic seizure regula-tion in the Genetically Epilepsy-Prone Rat (GEPR). Experiencein stereotaxic lesioning techniques, microdialysis or kindledseizures desirable. Requirements: doctorate with experience inneuropharmacology, neuroanatomy, neurophysiology or arelated discipline. Individuals who have completed the Ph.D.degree within one year of application will be considered for oneposition. For the second position, preference will be given toindividuals with one to two years of relevant postdoctoral expe-rience. Experience in electrophysiology is desirable but notessential.

The University of Illinois is an Affirmative Action/Equal Opportuni-ty Employer.

Send CV and names of three references to:Phillip C. Jobe, Ph.D., Chair, Department of Basic Sciences

University of Illinois College of Medicine at PeoriaP.O. Box 1649, Peoria, IL 61656.

BIOTECHNOLOGYBIOCMA ENGNEER/IENISAt Cetus Corporation, we are committed to maintaining aleading role in the development of biotechnology-basedproducts. Our Process Development Group has an immedi-ate opening for a Biochemical Engineer/Scientist with exper-tise in the area ofdownstream purification.You will have an understanding of the underlying engineer-ing principles of scale-up to rationally extrapolate laboratory/pilot scale purification findings and assess feasibility forcommercialization. You will perforn engineering analysesof purification operations including design and operation oflarge-scale chromatographic separations of proteins, as wellas review all purification process options and develop anengineeing view towards scalability by consulting withappropriate scientists and project engineering staff. Evalu-ation of costs, reliability, throughput and timing will requirea "hands-on" role in conducting research at the bench andpilot scale.We require a PhD, preferably in Chemical Engineering,although other disciplines with relevant experience will beconsidered, and a minimum of 1-2 years' experience inprotein purification. Industrial experience in protein purifi-cation would be an asset.Cetus offers an excellent salary and benefits package alongwith an environment that encourages innovation and growth.For consideration, please send your resume to Cetus Corpo-ration, Box BF, 1400 Fifty-Third Street, Emeryville, CA94608. We are an Equal Opportunity Employer.

CEEuSK_

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,q%I

The Macromolecular Sciences Department of Smith Kline &French Laboratories, located in suburban Philadelphia, PA, isseeking outstanding postdoctoral scientists to conduct struc-ture-function research on proteins and their macromolecularinteractions and the synthetic/genetic design of recognitionmolecules.

Candidates must have a Ph.D. in Chemistry, Biochemistry,Biophysics or related science. Expenience in one or moreof the following areas would be desirable: (1) proteincharacterization, (2) macromolecular interactions, (3)biophysical methods, (4) chemical modification and recom-binant DNA mutagenesis of proteins, (5) peptide synthesis.We offer an excellent compensation and benefits package andan attractive relocation policy as well as an exciting and activework environment that offers considerable opportunity forpersonal and professional growth. Resumes and names ofthree references should be sent to: Nancy Hasson, EmploymentAdministrator, SO100, Smith Kline & French Laboratories, P.O.Box 1539, King of Prussia, PA 19406-0939. We are an EqualOpportunity Employer, M/F/H/V.I _ j __~~~~~'I|*i-ii -|id5|;0 Z

U.S. PATENT AND TRADEMARK OFFICEPOSITION: Microbiologist/Patent Examiner Opportunity in-volves the scientific and legal evaluation of patent applica-tions involving recombinant DNA, molecular and cellularimmunology, molecular genetics, microorganisms, cell biolo-gy, cell culture, fermentation, enzymology or clinicalchemistry.QUALIFICATIONS: A full 4-year or longer professional curric-ulum in an accredited college or university leading to aBachelor's Degree or higher with specific study in MolecularBiology, Biochemistry, Immunology, Enzymology, Embryolo-gy, Protein Chemistry, Microbiology or Cell Biology.A Ph.D. or M.S. degree with relevant research experience ispreferred. A B.S. degree with significant research experiencewill be considered.Research Experience in any of the following areas would bebeneficial: DNA cloning, protein chemistry, gene expression,sequencing techniques, muteins, hybridoma technologies,monoclonal antibody applications, mammalian or plant celllines, cell culture, immunossays, hybridization techniques,fermentation, enzymatic reaction, diagnostics and automationof clinical analysis.SALARY: Dependent upon experience and qualifications.LOCATION OF POSITION: Arlington, VAFor further information contact:

Patent and Trademark OfficeOffice of Personnel, C&ECPK 1, Suite 700Washington, D.C. 20231703-557-3631Toll free: 800-368-3064

UCLA

CELL AND MOLECULARPHYSIOLOGYThe Department of Physiology invites applications fortenure track faculty positions at the level of

Assistant ProfessorOutstanding candidates working in any area of contem-porary physiology will be considered, but those insmooth muscle, reproduction and development, endocri-nology, sensory transduction, and the cardiovascularsystem are encouraged to apply. Successful candidatesare expected to have a Ph.D. or M.D. with postdoctoralexperience, to provide evidence that they can pursue avigorous, independent research program and to partici-pate in our teaching program.

Resources and an excellent environment exists fordeveloping an academic career within an interactivecommunity. Interested scientists should send their cur-riculum vitae, a statement of present and future researchinterest, and names of three references to: Ernest M.Wright, D.Sc., Professor and Chairman, Department ofPhysiology, UCLA School of Medicine, Los Angeles, CA90024-1751.

The University of Califomia is an Equal OpportunityAffirmative Action Employer.

MOLECULAR BIOLOGIST

Sphinx Biotechnologies is a young and rapidly growing com-pany whose mission is to help sick people through discovery,development, manufacturing and marketing of pharmaceuti-cals targeted towards signal transduction systems involvinglipid second messengers.

Molecular Biologist We are seeking a molecular biologist tointegrate with our discovery and development programs. Thesuccessful candidate will have a Ph.D. in molecular biology,biochemistry or related scientific field, at least three years ofpostdoctoral experience, expertise in the use of recombinantDNA techniques for the expression of proteins, and demon-strated ability to interact with a multidisciplinary research team.

Sphinx Biotechnologies offers excellent compensation andbenefits as well as an attractive relocation policy. We arelocated in the Research Triangle area of North Carolina whichoffers excellent living conditions and outstanding schools. Forconfidential consideration, please forward your curriculumvitae, list of publications and names of three references to:

Sphinx Biotechnologies CorporationPosition 104

Post Office Box 727Durham, NC 27702-0727L

oForest >Ecosystem Analyst

Responsible for analysis and reportingofdata froma national forest monitoring program. Interprettrends and patterns in indicators of forest conditionincluding correlation with spatial and temporaltrends in airpollution and other stressors. RequiresPhD in statistics, forestry, or ecology and 3 years

experience analyzing and reporting forestecosystem data. Knowledge of forest ecology re-

quired. Experience with temporal and spatialanalysis, analysis of covariance, sampling methods,experimental design, SAS, and computer program-ming required as well as excellent written and oralcommunication skills.

Experience with GIS, database management, andecosystem or forest modelling is desired. Submitcover letter, resume, unofficial transcripts and thenames of three professional references by May 5,1989 to:

Human Resources#4510-021/D89

NSI Technology Service1600 SW Western BiCorvallis, OR 9733

An Equal Opportunity EmFA subsidiary of Maflbch Intl

LIFESCIENTIST

Atlanta,Georgia

Office

e Corp.Ivd.3

ployer,1.Corp.

Syracuse Research Corporation, a leaderin the field of assessment of potentially-hazardous substances, is expanding itsbusiness and has openings for ScientificWriters with expertise in one or more ofthe following disciplines:* Mammalian Toxicology* Mammalian Biology/Physiology* Biochemistry* Epidemiology/Biostatistics* Pharmacology* Carcinogenesis/Mutagenesis/Teratogenesis

These non-laboratory positions involvethe written evaluation of published ex-

perimental data concerning the adverseeffects of chemical pollutants upon labanimals and humans and the environ-mental fate of those chemicals. PhD, MSor other advanced Degree preferred.Applicants must have demonstratedskills in technical writing.SRC offers competitive salaries andbenefits and a creative and challengingwork environment. Send resume to:

Syracuse Research Corp.Personnel Dept.Merrill LaneSyracuse, NY 13210

An Equal Opportunity Empnloyer

TOXICOLOGISTSDelta Environmental Consultants, Inc is seeking ex-perienced toxicologists to assume responsibilitiesfor: conducting independent toxicology projects inrelation to environmental impact statements, haz-ardous waste management and endangerment as-sessments; providing project support for site assess-ments, remedial investigations and engineeringactivities conducting multiple exposure pathwayhealth risk assessments; preparing exposure guide-line documents and managing other projects asassigned.

This individual should havea Master's degree in Tox-icology or a related field, at least two years of workexperience as a regulatory or consulting toxicolo-gist and possess strong communication skills, bothoral and written. A working knowledge of industrialhygiene practice would be helpful.

Interested candidates should submit their resumeand salary requirements to: Deborah L Coleman,Director of Benefits and Employment, DELTA ENVi-RONMENTAL CONSULTANTS, INC., 1801 Highway 8,

Suite 114, St. Paul, MN 55112. EOE MIF.

The perfect environment for people

EnvironmentalConsultants, Inc.

Research Assistants/AssociatesBiochemistry/Molecular Biology

Genentech, Inc., a leader in the field of biotechnology,has opportunities available for Research Assistants/Associates. Working on programs to discover new humanpharmaceuticals, these positions offer a challenging oppor-tunity to be a key team participant.1Tpical requirements include a BS/MS in Biochemistry,Molecular Biology, Chemistry or closely related scientificfield. Candidates must have a minimum of 2 years experi-ence in one or more of the following areas: biochemistrytechniques including chromatography, electrophoresis, pro-tein purification and characterization, cell culture andassay development: molecular and cell biology techniquesincluding DNA cloning, expression and sequencing.Genentech, Inc. offers an excellent salary and benefitspackage coupled with the opportunity to make a signifi-cant contribution to our organization. For consideration,please send your resume to Yvonne Davino, HumanResources Dept. RA, Genentech, Inc., 460 Point San BrunoBlvd., South San Francisco, CA 94080. We actively supportand promote affirmative action and equal employmentopportunity. Women and minorities are encouraged toapply

Genentech, Inc.

POSITIONS OPEN

POSTDOCTORAL POSMIIONS (TWO)MICROBIOLOGY/BIOCHEMISTRY/FERMEN-

TATION SCIENCE: Two postdoctoral positionsavailable on or before 1 July 1989 for study of themicrobiology and biochemistry of microbes from ex-treme habitats (temperature, salinity, pH, and substrateavailability). Background in one or more ofthe followingareas preferred: culture of chemolithotrophic and/orobligate anaerobic microorganisms, biochemistry of sul-fur metabolism and/or cellular energy generation reac-tions, fermentor design/operation, cell yield optimiza-tion. Opportunity to interact with a multidisciplinarygroup of microbiologists, engineers and biochemists.Salary range $20,000 to $26,000 per year. Send resumeto: UCLA Center for the Study of Life in ExtremeEnvironments, Department of Microbiology, 5304LS, UCLA, 405 Hilgard Avenue, Los Angeles, CA90024. For further information, write the above addressor call: 213-206-8201.

POSTDOCTORAIJRESEARCH ASSOCIATE.A position is available for an individual with a Ph.D. inpharmacology, biochemnistry, or cell physiology. Thesuccessful applicant will be engaged in rearch involvingthe effects and mechanisms of action of atrial natriureticfactor and cyclic GMP in cultured vascular and renal cels,with particular emphasis on calcium, cyclic nudeotidemetabolism and cell proliferation. Competitive salary andfringe benefits are available. Appointment will be for 1year, with possibility of renewal. Please send curriculumvitae and three letters of reeommcndation to: Dr. AvivHassid, Dqep nt of Pharmacology, Ncw YorkMedical College, Valhalla, NY 10595, or call: 914-993-4135. New York Medical College is an Equal Opportu-nity/Ajfirnative Action Employer.

POSTDOCTORAL RESEARCH ASSOCIATE[Chemist, Cell Biologist, or Immunologist, GS-11/12($28,852 to $34,580)]. Two positions available immedi-ately, second year negotiable, with the U.S. DepartmentofAgculture, Agricultural Research Service VcterinaryToxicology Research Laboratory, College Station, Texas,located on a sixty-acre moder facilit adjacent to theCollege ofVeterinary Medicine, TexasA&M University.One position involves encapsulation of drugs and myco-toxins and the mechanism of interaction of drugs andmycotoxins with cell membranes. The other positioninvolves the preparation of monodonal antibody basedELISA's for detection of drug residues in animal fluids.This research is part of a high priority Agency project ofinterest to FDA and FSIS. Ph.D. obtained in the last 3years is desired. Send applications to: Dr. J. R De-Loach, USDA-ARS-SPA, VTERL Complex, Route5, Box 810, College Station, TX 77840. For applica-tion procedures, contact Carol Gramlich: 301-344-1508. Applications should be marked S-9-010.

An Equal Opportunity Employer.

POSTDOCTORALIRESEARCH ASSOCIATEpositions for studies of mcasurements of redox metabo-lism and oxygen concentrations in viable cells, tissucs,and in vivo. Prefer background in cell biology, nutrition-al sciences, biochemistry, or electron spin resonance.Available immediately but may start later. Send curricu-lum vitae and names of three refcrences to: HaroldSwartz, M.D., Ph.D., Deprtments of Medicinc andBiophysics, University of Illinois, College of Medi-cine at Urbana-Cham 506 Southi Mathews,Urbana, IL 61801.

The University of Illinois is an Affirmative Action/EqualOpportunity Employer.

POSTDOCTORAL RESEARCH ASSOCIATEposition available immediately for 2 years at Texas A&MUniversity, Department ofEntomology, College Station,Texas to study molecular biology of gene expressionusing recombinant forms of a genetically engineeredbacilovirus. Successful applicant should be trained inrecombinant DNA techniques; experience in cell andtissue culture also required for the conduct of theresearch. Salary $22,000 to $25,000. Send curriculumvitae and names of three references preferably by 15 Mav1989 to: Dr. Max D. Summers, Distinguished Profes-sor, Department of Entomology, Texas A&M Uni-versity, College Station, TX 77843.

An Equal Opportunity Employer.

POSTDOCTORAL RESEARCH ASSOCIATEposition available to study the role of trophic factors inncuronal regeneration and in neurodegenerative diseases.Background in cell biology, biochemnistry, or molecularbiology desirable. Send curriculum vitae and narnes ofthrce references to: Dr. F. Hefti, Andrus GerontologyCenter, Univcrsity ofSouthern California, Los Ange-les, CA 90089-0191.

POSTDOCTORALRESEARCH ASSOCIATEpositions (two) available immediately for multidis-ciplinary study of neurotransmitter-receptor interactionsin the CNS. Emphasis on receptor: binding, distribution(autoradiography), regulation, and second messengersystems. Applicants should have some background inneuroanatomy, neuropharmacology and/or neurochem-istry. Salarv commensurate with experience. Send curric-ulum vitae, statement of research interests and the namesof three references to: James K. Wamsley, Ph.D.,Director ofResearch, The Neuropsychiatric Institute,700 First Avenue South, Fargo, ND 58107.

POSTDOCTORAL RESEARCH ASSOCIATEA position is available at the level of postdoctoral

research associate to teach medical physiology to firstyear medical, dental, and pharmacy students, to teachgraduate level course in physiology, to conduct interdis-ciplinary research on the central nervous system effects ofbacterial products and immune response modifiers, andto director support personnel. Other special require-ments are: knowledge and experience in use of HPLCand gas chromatography, knowledge and experience inuse of mass spectrometry, experience in microbiologicaltechniques including growth of bacteria and isolation ofvarious bacerial products and relevant publications. Theannual salary willbe$24,000. Applicants with a Ph.D.degree send curriculum vitae and the names of threereferences to: Dr. Edward G. Schneider, ActinF Chair-man, Department ofPhysiology and Biophysics, Uni-versity of Tennessee, Memphis, 894 Union Avenue,Memphis, TN 38163. An Equal Opportunity/AfirmativeAction Employer. Minorities and women are encouraged toapply.

POSTDOCTORAL RESEARCH POSImIONS-TWO POSTDOCTORAL RESEARCH POSI-TIONS ARE AVAILABLE IMMEDIATELY in aproductive, well-funded NIH group to investigate themechanism of interaction of ethanol and anesthetics withbiological membranes and identify the structural/chemi-cal basis ofacquired tolerance to these agents. Experiencein either biological applications ofNMR/ESR or in state-of-the-art methods of-isolation and analysis ofmembranelipid constituents is required. Facilities include multinu-clear Bruker AM 360 wide-bore NMR and IBMER200D ESR. Highly competitive salarv offered. Sendcurriculum vitae, a brief statement of research interestand names of three references to: Dr. Theodore F.Tarasei, Thomas Jefferson University, Departmentof Pathology and Cell Biology, Room 264 JeffersonAlumni H4 1020 Locust stret, Philadelphia, PA19107. Equal Opportunity Employer.

NAVAL DENTAL RESEARCH INSTITUTEResearch Positions Available for U.S. CitizensDivision Head Position available for IMMUNOLO-

GIST or Immunochemist. Candidates should havePh.D., experience in immunoassay development, immu-nochemical analysis, cell-mediated immumty and humanimmune response mechanisms. Position # LDS 0031.ORAL EPIDEMIOLOGY position available for indi-vidual with M.S. or higher in Epidemiology, PublicHealth, Statistics, Biochemistry or Dentist (publichealth). Candidate must have published in the field oforal epidemiology or clinical research. Position # LDS0034. RESEARCH DENTAL HYGIENIST withM.S. in dental hygiene, chemistry, immunology, ormicrobiology, to conduct research. Requires valid statehygienist license. Position # LDS 0032.

Interested individuals should send resume, LDS# andtwo letters of reference to: Ms. Peggy Hough, StaingDivision, Consolidated Civilian Personnel OfficeBuilding 1-H, Great Lakes, IL 60088-5200.

The United States Navy is an EqualOpportunity and Afirmative Action Employer.

PRE- AND POSTDOCTORAL TRAINING INNEUROBIOLOGY is available through the Cellularand Clinical Neurobiology Program at Wayne StateUniversitv School of Medicine. The 13 participatinginvestigators offer an integrated team-taught curriculumand a wide variety of laboratory experiences, includingmolecular genetic, neurochemical, electrophysiologica,behavioral and clinical analyses of neurotransmitters andreceptors and their possible involvement in neuropsvchi-atric disorders. Graduate fellowship positions, whichprovide a beginning stipend of $11,500 plus insuranceand tuition allowances, are still available for qualifiedapplicants for fall 1989. For further information contact:Dr. Michael Bannon, Celiular and Clinical Neurobi-ology Program, Center for Cell Biology, Sinai Hospi-tal of Detoit, 6767 West Outer Drive, Detroit, MI48235 or call 313493-5167.

RESEARCH ASSISTANTCedars-Sinai Medical Center, an 1120-bed teaching

research facility, has a postdoctoral position available inmolecular biology/genetics to analyze genome structure,junction, and evolution around the alpha-globin genecomplex.

Applicants should have a Ph.D. and/or M.D. andexpenence in molecular biology.

For immediate consideration, please send resumes to:Mark W. Sdhmitz

Cedars-Sinai Medical CenterEmployee Relations

8700 1Bcverly BoulevardBrown Building, 1st FloorLos Angeles, CA 90048

RESEARCH ASSOCIATE in neurophysiology, in-volves patch clamping and whole cell recording fromphotoreceptors of Drosophila and larger flies. Studiesconcern the light-dependent cation channel, effect ofvarious agents on the photoresponse, and noise analysisof photoreceptor mutants. Ph.D. in biologv or neuro-physiology with strong experience in single-cell electricalrecording is desirable. Send curriculum vitae, reprintsand three letters of reference to: Dr. R. S. Stephenson,Department of Biological Sciences, Wayne State Uni-versity, Dctroit, MI 48202. Telephone: 313-577-2869. An Equal Opportunity/Afirmative Action Employer.

RESEARCH ASSOCIATEFOR PATHOLOGY

The Department of Pathology and Laboratory Medi-cine at Mount Sinai Medical Center of Greater Miami isseeking an AP/CP Board-certified pathologist to occupya junior faculty position within the department. Thecandidate must have training and experience in DNA insitu hybridization and will be expected to direct a DNAin situ hybridization research laboratory. The candidatemust also have a strong background in surgical pathologyand immunohistochemistry with particular emphasis andexpertise in oncologic pathology and a proven trackrecord of publications in these fields. The position alsoentails teaching of pathology residents and medical stu-dents. Send curriculum vitae to: Morton J. Robinson,M.D., Director, Department ofPathology and Labo-ratory Medicine, Mount Sinai Mcdical Center, 4300Alton Road, Miami Beach, FL 33140.

RESEARCH ASSOCIATE IN MUSCLE PRO-TEIN CHEMISTRY to study structure-function rela-tionships in muscle calcium-regulatory and -transportproteins. Research involves protein/peptide purification,sequencing and chemical modification, working in awell-equipped, established laboratory. Salary dependenton traming and experience. Respond to: Dr. John H.Collins, Department of Biological Chemistry, Uni-versity of Maryland School of Medicine, Baltimore,MD 21201. Equal Opportunity Employer.

RESEARCH FELLOWIN NEUROPHYSIOLOGY

Experience investigating neuroanatomical and neuro-immunohistochemical central nociceptive mechanismswith some commitment to electroneurophysiology. Ded-icated MGH-Harvard Neuroscience Center. Positionavailable 1 September 1989. Salarv range commensuratewith experience. Send credentials to: Dr. Charles Po-Jti, Massachusetts Gencral Hospital, Boston, MA02114.

SCIENCE, VOL. 244392

POSITIONS OPEN POSITIONS OPEN

Health Effects

Research LaboratoryResearch Triangle Park, NC

UPS.

EnvironmentalProtection

RgencyAn Equal Opportunity Employer

The US. Environmental Protection Agency (EPA) isseeking candidates for the position of Director, En-vironmental Toxicology Division, Health EffectsResearch Laboratory (HERL). This position is locatedin Research Triangle Park, NC and is a permanent full-time position witha salary range of $57,158 to $74,303per annum, commensurate with qualifications.HERL has a staffofabout300, over 100 ofwhom holddoctoral level degrees. The Laboratory has a diverseprogram which includes in vitro, animal, humanclinical, and epidemiologial research designed to ad-dress issues related to the health effects of air andwater chemical and biological pollutants.The Environmental Toxicology DMison (ETD) conductsresearch to determine the health effects ofinhaled en-vironmental pollutants. The research is designed todetermine cause and effects relationships at pollutantconcentrations which mimic those occurring in theenvironment. Particular emphasis is placed on thedevelopment and application of improved methodswhich enable significant advancement in theknowledge of the health effects of air pollutants. In-tense investigations center on the pulmonaryand car-diovascular systems, the immune system, hostdefense mechanisms againstinfetious and neoplasticdisease and other extrapulmonary systems which aresusceptible to inhaled pollutants. The Division servesas a primary technical resource within the Agency foractivities requiring expertise in animal inhalationstudies and in the health effects of common airpollutants. The program includes both intramural in-vestigations and extramural arrngements with univer-

sities, industry, private research instions and othergovernmentagencies. The primary responsibilities ofthe Director are to direct and manage the program.This includes developing the program to meet theevolving needs of EPA, presenting the program,developing and managing budgets, supervising thestaff, directing the progress of the program, and en-suring the scientific quality and productivity of theprogram.The preferred candidate for this position wouldpossess the following qualifications:

1. Aovanced degree in a biological or environmentaldiscipline with at least six years of professional ex-perience in either of these areas. Applicable graduatecoursework may be substituted for a portion of thepreferred experience.

2. Experience as a supervisor of a scientific/pro-fessional staff

3. Recognized scientific expertise as evidenced bmultiple publications in peer-reviewed literature andinvitations to participate in national and internationalmeetings/panels.4 Proven ability to provide leadership in directing

the development and progress of a creative and ef-fective multidisciplinary research program.

5. US Citizenship is required.Forward curriculum vitae and names of threereferences priorto May 28, 1989 to: Dr. Lwence WReiter, clo Tel Burrell, HRMD (MD-29), U.S. En-vironmental ProtectionAgency, Research TrianglePark, NC 27711.

BS/MS SCIENTISTS

Pharmaceutical Research

Equal Opportunity Employer

For more than a century, scientists at ELI LILLY AND COMPANY havedeveloped innovative, high quality pharmaceutical products. Lilly invests over$500 million annually in research-and-development programs. More than 3,000scientists at the company's Lilly Research Laboratories are pursuing creativeresearch programs that involve many important health care needs.

To further build its research capabilities, Lilly is seeking self-motivated,innovative scientists to join the Pharmaceutical Research Group and study thephysical and chemical characterization of proteins. The ideal candidate willhave the following qualifications:* Bachelor's or Master's degree in biochemistry, organic chemistry ora related discipline.

* Working knowledge of analytical, physical and protein chemistry.* Skill in quantitative calculations and mathematical concepts.* Experience with chromatography, electrophoresis, spectroscopy andcomputer analysis is desirable.Eli Lilly and Company is committed to scientific excellence. Lilly provides

a stimulating professional atmosphere with many opportunities forcollaborative, multidisciplinary research. The company offers an attractivetotal compensation program. Entry level and salary will be based upon eachcandidate's experience.

For prompt consideration, please forward your resume to:Blake A. CaleyScience Recruitment (PR-1)Eli Lilly and CompanyLilly Corporate CenterIndianapolis, Indiana 46285

POSITIONS OPEN

RESEARCH ASSOCIATEPROFESSIONAL ASSISTANT

The Jackson Laboratory, a center for research inmammalian gcnetics located on the coast of Maine, hasan immediate opening for a research associate/profes-sional assistant to conduct basic research experimentsaimed at understanding the mechanisms of ras proteinaction. Experimental methods will indude in vitro muta-genesis, gene transfer, protein biochemistry and cellgcnetics, induding gene targeting. B.S. and relevantexperience required. Applicants should send curriculumvitae and names of three references to: Harold Wheeler,Employment Managr, The Jackson Laboratory, 600Main Street, B arHarbor, ME 04609. Tcelphone:207-288-3371. Affirmative Action/Equal Opportunity Em-ployer MIF.

UNWERSITY OF SOUTH FLORIDARESEARCH ASSOCIATES. Two-year job assign-

ments available immediately. The Division of PediatricEndocrinology of the USF College of Medicine invitesapplications. Applicants should have M.D. or Ph.D.degrees and additional postgraduate expericnce. Salarycommensurate with training/achievement. Applicantsshould submit curriculum vitae and names of fve refer-ences to: Dr. Barry B. Bercu, Professor of Pediatrics,U sity of South Florida College ofMedicine, AllChildre's Hopital P.O. Box 31020, St. Petersburg,FL 33731-8920. USF is an Affirmative Action/EqualOpporunity Employer.

RESEARCH SCIENTISTRescarch Scientist nceded to develop synthetic meth-

ods for drug absorption research. Require Ph.D. inpolymer chemistry and knowlcdge of using advancedistrumentation techniques like FI-IR, high-resolutionNMR, GPC, pyrolysis GC-MS, and DSC, strong back-ground in polymer structure correlations to desired

ogical properties and a working knowledge of poly-menric drug delivery systems and special requircment formedical polmers. Saary: $36,000 pcr year. Job OrderNo. 3933252. Contact: Utah Job Service, 1234 SouthMain Street, P.O. Box 11750, Salt Lake City, UT84147.

RESEARCH VETERINARIAN to perform surgi-cal procedures to derive germ-free animals and performnecropy. Test all vaccines, reagents and biologic rawmatel (serum) pursuant to federal regulations and in-house standards, utilizing cell culture, virus titration,immunoassay, biochemical analysis and animal testings.Sample vaccmes for federal agencies. Supervise technicalstaff on research projects. Supervise animal care andfacility inspections. Provide veterinary expertise in mar-keting cfforts at trade fairs. Requires D.V.M. or equiva-lent, plus M.S. in microbiology or a closely related field,also requires some experience with animal vaccination,cell culture, virus isolation, virus titration, and immuno-assay. $27,000 per year 40 hours per week; 8:00 a.m. to5:00 p.m. Apply at or send resume to: Job Service ofIowa, 150 Des Moincs Strect, Des Moines, IA 50309.Refer to Job #IA 0224305.

SCIENTIFIC PROGRAMMINGFein-Marquart Associates (FMA) is a small, estab-

lished, computer software research and development firnspecializing in scientific programning and database sys-tems, espeially cheml information systems and labo-ratory information management systems. Projects vary insize and use a variety of sophisticated computer environ-ments-from microcomputers to large mainframes.As part of its current expansion, FMA seeks experi-

enced programmers with scientific degree(s) and Fortranenperence.

Please send resume to: Fein-Marquart Associates,Inc., 7215 York Road, Balimore, MD 21212. Tele-phone: 301-821-5980.

SUPERVISORY RESEARCH CHEMISTS. FAACivil Aeromedical Institute, Oklahoma City, Oklahoma.Two positions in Carecr Civil Service. One position willsupervise the Combustion Toxicology Research Pro-gram; the other position will be responsible for develop-ing the team and new program in Forensic ToxicologyResearch. Contact: Shirley Cox, 405-686-4506, orqualification requirements and application forms. EqualOpportunity Employer.

SENIOR RESEARCH ASSOCIATEPERMANENT POSMON

W1TH ADVANCEMENT POSSIBILITIESExperienced Glycoconjugate Biochemist at a Universi-

ty Hospital. Bench-work-oriented individual with quan-ttative working habits for investigation of carbohydratemoieties of human cancer cell membranes. Doctoraterequired. Technical help available. Outstanding salaryand excellent benefits. Position is not dependent ongrants. Please send curriculum vitae, bibliography anddetails of cxpertise to: Box 54, SCIENCE.

Equal Opporunity Employer M/F.

TOXICOLOGIST-The State of Washington is ac-ccpting applications for State Toxicologist. Requires:knowledge and skill in forensic toxicology; ability toadminister laboratory and statewide toxicology program;Ph.D.; diplomate, American Board ofForensic Toxicolo-gy (or eligible). Respond by 1 June 1989. Send resumeto: George G. Ishii, Search Committee, WashingtonState Patrol, 6604 Martin Way, PQ-11, Olympia,WA 98504. Telephone: 206438-7221.

University of California, Los Angeles (UCLA) Urolo-gy Division seeks Board-certified UROLOGIST withexprtise in renal transplantation for faculty position.Requirements: proven a i1i to organ clinical train-ing; ability to collaborate in immunology research; expc-rience in reconstructive and pediatric urology; exccllntsurgical skills. Applicants should contact: Tic UCLADivns of Urology, Los Angeles, CA 90024-1738.UCLA is an Equal Opportunity/Affirmative Action Employer.

VIROLOGISTWIHANINTEREST

IN ANTIVIRAL AGENTSA virologist with postdoctoral experience and an inter-

cst in antiviral research is being sought to play a majorrole in two recently fully-funded grants. The candidatewill explore the active components of natural productsfound to be effective in vivo for their effect on thereplication cycle and pathogenesis of hepadna and retro-viruses. The successful candidate should have a soundknowledge of molecular biology, tissue culture tech-niques and animal models. In addition, this individualwill supervise the implementation of assays detectinghepatitis B markers as well as markers of hepatocellularcarcinoma. Although this position is nontenure-track,the candidate in time will be encouraged to seek indepen-dent funding topursue related research, which couldleadto a tenure-track position. Salary will be commensuratewith the candidate's qualifications. Please send curricu-lum vitae and letters of reference to: Search Committeefor Virologist, Personnel Department, Fox ChaseCancer Center, 7701 Burholme Avenue, Philadel-phia, PA 19111. The Center is an Equal OpportunityEmployer.

SYMPOSIUM

CALL FOR PAPERSEIGHTH INTERNATIONAL OCEANDISPOSAL SYMPOSIUM (8IODS)

Dubrovnik, Yugoslavia9 to 13 October 1989

The overall objectives and scope of 8IODS are:* Provide a forum for exchangc of ideas and informa-

tion among ivestigators involved in manne pollutionand oceanic disposal research* Enhance the scientific consideration ofwaste dispos-

al and marine pollution processes* Generat mendations and guidelines for future

studies of oceanic disposal practicesThe 8IODS will feature special sessions and invited

keynote speakers. The Co-Chaimen of8IODS are: Dr.Velimir Pravdk, Ruder BAskovic, Zagreb, and Dr.Adam Benovic, Biokical Institute, Dubrovnik, Yugo-slavia.Send 250-word abstract by 31 May 1989 to:

Dr. Iver W. DuedallOg Cdae~Co-ChairaDq tof aphy and

-Ocean BFlorida Institute of Technolgy

Melbourne, FL 32901

To acknowledge and promote excellence in the field oftoxicology, the International Life Sciences Institute(ILSI) annually sponsors the KENNETH MORGAR-ELDGE AWARD. The $5,000 award to be presented atILSrs Annual Meeting, January 1990. Recipient mustaccept in person and present short overview of research.Candidates must be from academia, government orindustry. All documents must be in Engsh. Deadline 1September 1989. For application contact: F. DeLuca,ILSI, 1126 16th Street, NW, Washington, DC20036. Tdelphonc: 202-659-0789.

CONFERENCES

CLINICAL CHRONOBIOLOGYThe International Society for Chronobiology (ISC)

and the National Institutes ofHealth are sponsoring a 1-day conference, 20 June 1989, dealing with the applica-tions of biological rhythms in diagnosis and treatment.The meeting will be hedinLipsett Auditorium in theClinical Center at the NIH. Although there is no regis-tration fee for the meeting, notifcation of intent toattend would be appreciated. Contact: Dr. Kirt Vener,NIAMS, Wcstwood Building, Room 5A-07, Nation-al Institutes of Health, Bethesda, MD 20892; or call:301496-0754. This meeting precedes the XX Confer-ence of the ISC in Bethesda, Maryland, 20-24 June1989.

FELLOWSHIPS

POSTDOCTORAL FELLOWSHIPSLIFE SCIENCES

RESEARCH FOUNDATION (LSRF)The LSRF solicits monies from industry, foundations

and individuals to support postdoctoral fellowships inthe life sciences. Active solicitation offunds continues forwhich we need the assistance of all concerned individuals.

Eligibility: Three-year fellowships will be awarded ona competitive basis to graduates with M.D. or Ph.D.degrees in any field of the life sciences. U.S. citizens areeligible to applywith no restrictions on the laboratory oftheir choice. 7oreig applicants are eligibk for study inU.S. laboratories. Only research in nonprofit institutionswill be supported. Those who are changing their field ofresearch by way of a second postdoctoral or as anindependent rcsearch associate are encouraged to apply.

Timetable: Application deadline is 1 October 1989,for award as early as summer 1990. Awards will beannounced in March 1990.

Plcase note address change for submiting applica-tions:LSRF, c/o Lewis Thomas Laboratorics, Princeton

University, Princeton, NJ 08544.

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SCIENCE, VOL. 244

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