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PureTech Health to Present at the Jefferies 2016 Healthcare Conference in London Boston, Massachusetts, November 2, 2016 PureTech Health plc (“PureTech” or the “Company”, LSE: PRTC), a cross-disciplinary biotech company developing 21 st century medicines, today announced that Daphne Zohar, PureTech Health’s Chief Executive Officer, will present at the Jefferies 2016 London Healthcare Conference on Wednesday, November 16, at 4:00pm GMT. A webcast of the presentation will be available at http://puretechhealth.com/investors.php under the Reports and Presentations tab. About PureTech Health PureTech Health (PureTech Health plc, PRTC.L) is a cross-disciplinary biotech company creating 21 st century medicines that modulate the adaptive human systems. Our therapies target the immune, nervous, and gastro-intestinal systems by addressing the underlying pathophysiology of disease from a systems perspective rather than through a single receptor or pathway. We are advancing more than 20 clinical studies across our pipeline, with five human proof-of-concept studies and multiple pivotal or registration studies expected to read out in the next two years. PureTech Health’s rich and growing research and development pipeline has been developed in collaboration with some of the world’s leading scientific experts, who along with PureTech's experienced team and board analyze more than 650 scientific discoveries per year to identify and advance the opportunities we believe hold the most promise for patients. This process places PureTech Health on the cutting edge of ground-breaking science and technological innovation and leads the Company between and beyond existing disciplines. For more information, visit www.puretechhealth.com or connect with us on Twitter. Forward Looking Statement This press release contains statements that are or may be forward-looking statements, including statements that relate to the company's future prospects, developments and strategies. The forward- looking statements are based on current expectations and are subject to known and unknown risks and uncertainties that could cause actual results, performance and achievements to differ materially from current expectations, including, but not limited to, those risks and uncertainties described in the risk factors included in the company's regulatory filings. These forward-looking statements are based on assumptions regarding the present and future business strategies of the company and the environment in which it will operate in the future. Each forward-looking statement speaks only as at the date of this press release. Except as required by law, regulatory requirement, the Listing Rules and the Disclosure and Transparency Rules, neither the company nor any other party intends to update or revise these forward- looking statements, whether as a result of new information, future events or otherwise. ### Contact: PureTech

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PureTechHealthtoPresentattheJefferies2016HealthcareConferenceinLondonBoston,Massachusetts,November2,2016–PureTechHealthplc(“PureTech”orthe“Company”,LSE:PRTC),across-disciplinarybiotechcompanydeveloping21stcenturymedicines,todayannouncedthatDaphneZohar,PureTechHealth’sChiefExecutiveOfficer,willpresentattheJefferies2016LondonHealthcareConferenceonWednesday,November16,at4:00pmGMT.Awebcastofthepresentationwillbeavailableathttp://puretechhealth.com/investors.phpundertheReportsandPresentationstab.

AboutPureTechHealthPureTech Health (PureTech Health plc, PRTC.L) is a cross-disciplinary biotech company creating 21stcentury medicines that modulate the adaptive human systems. Our therapies target the immune,nervous,andgastro-intestinalsystemsbyaddressingtheunderlyingpathophysiologyofdiseasefromasystemsperspectiveratherthanthroughasinglereceptororpathway.Weareadvancingmorethan20clinical studies across our pipeline, with five human proof-of-concept studies andmultiple pivotal orregistration studies expected to read out in the next two years. PureTech Health’s rich and growingresearchanddevelopmentpipelinehasbeendevelopedincollaborationwithsomeoftheworld’sleadingscientific experts, who along with PureTech's experienced team and board analyze more than 650scientificdiscoveriesperyeartoidentifyandadvancetheopportunitieswebelieveholdthemostpromiseforpatients.ThisprocessplacesPureTechHealthon thecuttingedgeofground-breaking scienceandtechnological innovation and leads the Company between and beyond existing disciplines. For moreinformation,visitwww.puretechhealth.comorconnectwithusonTwitter.

ForwardLookingStatement This press release contains statements that are or may be forward-looking statements, includingstatements that relate to thecompany's futureprospects,developmentsandstrategies.The forward-lookingstatementsarebasedoncurrentexpectationsandaresubjecttoknownandunknownrisksanduncertainties that couldcauseactual results,performanceandachievements todiffermaterially fromcurrent expectations, including, but not limited to, those risks and uncertainties described in the riskfactors included in the company's regulatory filings. These forward-looking statements are based onassumptionsregardingthepresentandfuturebusinessstrategiesofthecompanyandtheenvironmentinwhichitwilloperateinthefuture.Eachforward-lookingstatementspeaksonlyasatthedateofthispressrelease.Exceptasrequiredbylaw,regulatoryrequirement,theListingRulesandtheDisclosureandTransparencyRules,neitherthecompanynoranyotherpartyintendstoupdateorrevisetheseforward-lookingstatements,whetherasaresultofnewinformation,futureeventsorotherwise.

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PureTech

AllisonMeadDirector,CommunicationsandInvestorRelations+16176513156amead@puretechhealth.com