PUBLICATIONS AND ACADEMIC PRESENTATIONS

(During Ph.D. work)

Published Pap~rs:

1. Nagsen Gautam, R.P. Singh, R. Pratap and S.K. Singh, Liquid chromatographic­tandem mass spectrometry assay for quantitation of a novel antidiabetic S002-853 in rat plasma and its application to pharmacokinetic study. Biomedical Chromatography, 24,692-698 (2010).

2. Nagsen Gautam, H.N. Kushwaha, R. Pratap and S.K. Singh, In-situ absorption, protein binding and pharmacokinetic studies of new synthetic antidiabetic and antidyslipidemic flavone derivative S002-853 in rats. Journal of pharmacy and pharmacology. 62, 604-609 (2010).

3. R.P. Singh, S. Sabarinath, Nagsen Gautam, R.C. Gupta and S.K. Singh, Liquid chromatographic tandem mass spectrometric assay for quantification of 97/78 and its metabolite 97/63, a promising trioxane antimalarial in monkey plasma. Journal of Chromatography B, 877,2074-2080 (2009).

4. R.P. Singh, S. Sabarinath, Nagsen Gautam, R.C. Gupta and S.K. Singh, Pharmacokinetic study of a novel, synthetic trioxane-antimalarial compound 97-78 in rats using LC-MS/MS method for quantification. Arzneimittel-Forschung Drug Research Accepted 9 April, 2010 (In press).

Published Abstracts:

5. Nagsen Gautam, H.N. Kushwaha R. Pratap and S.K. Singh, Excretion study of a novel antidiabetic S002-853 in rat urine and feces quantified by LC-MS/MS method. Medicinal Chemistry Research, 19, S91-92, 2010.

6. H.N. Kushwaha, Nagsen Gautam, and S.K. Singh, Effect of carbamazepine- an antiepileptic on pharmacokinetics profile of an antimalarial trioxane in rats. Medicinal Chemistry Research, 19, S68-69, 2010.

Book Chapter:

1. H.N. Kushwaha, Nagsen Gautam, and S.K. Singh, LC-MS/MS assay for quantification of 97/78 and its metabolite 97/63, a promising trioxane antimalarial in human plasma, 11'11 JSMAS-TRJCON-2009 (ISBN: 978-81-904442-2-4) S.K. Aggrarwal, P.G. Jaison et al. (Editors), p 342-346 (2009).

Academic Presentations in International Conference/ Symposium:

1. Nagsen Gautam and S.K. Singh. A sensitive and . selective liquid chromatographic-tandem mass spectrometry assay for quantitation of a novel antidiabetic flavonoid in rat plasma and its application to pharmacokinetic study. 20'11 International conference on Pharmaceutical and biomedical analysis March, 2009, Agra, India. (Poster)

2. Nagsen Gautam, H.N. Kushwaha and S.K. Singh, Excretion study of a novel antidiabetic S002-853 in rat urine and feces quantified by LC-MS/MS method, 4th International Symposium on Current Trends in Drug Discovery Research, February 17-21,2010 at CDRI, Lucknow, India. (Poster)

3. Nagsen Gautam, H.N. Kushwaha, H. Kumar, R. Pratap and S.K. Singh, Pharmacokinetic and excretion studies of a novel antidiabetic S002-857 in rats. 2nd International Symposium on Dntg Metabolism and Pharmacokinetics, Applications toward Dntg Discovery and Development, February 2010, NIPER, Punjab, India. (Poster)

4. Nagsen Gautam, H. Kumar, H.N. Kushwaha, and S.K. Singh, Pharmacokinetics, SGF/SIF, and in-situ abso~tion study of a novel antidiabetic compound S002-857 synthesized by CDRI, 2n International Symposium on Dntg Metabolism and Pharmacokinetics, Applications toward Drug Discovery and Development, February 2010, NIPER, Punjab, India. (Poster)

5. H.N. Kushwaha, Nagsen Gautam, H. Kumar, and S.K. Singh, Effect of gabapentin - an anti epileptic on pharmacokinetics profile of 97-78, an antimalarial trioxane in rats, 2nd International Symposium on Dntg Metabolism and Pharmacokinetics, Applications toward Drug Discovery and Development, February 2010, NIPER, Punjab, India. (Poster)