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PTSD and Other Invisible Wounds affecting our Service Members and Veterans 1 Alan Peterson, PhD, ABPP

PTSD and Other Invisible Wounds affecting our Service

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Page 1: PTSD and Other Invisible Wounds affecting our Service

PTSD and Other Invisible Wounds affecting our

Service Members and Veterans

1

Alan Peterson, PhD, ABPP

Page 2: PTSD and Other Invisible Wounds affecting our Service

Alan Peterson, PhD, ABPP• Retired USAF Lt Col Clinical Health Psychologist

• Former Chair, Department of Psychology at Wilford Hall

• Deployed in support of Operations Noble Eagle, Enduring

Freedom, and Iraqi Freedom

• Professor and Chief of Division of Behavioral Medicine at

University of Texas Health Science Center at San Antonio

• Research Health Scientist, San Antonio VA

2

• Professor, University of Texas at

San Antonio

• Director, STRONG STAR

Consortium, Consortium to

Alleviate PTSD, and National

Center for Warrior Resiliency

Page 3: PTSD and Other Invisible Wounds affecting our Service

Signature Injuries of OEF/OIF/OND

• Amputations

• Burns

• Posttraumatic Stress Disorder (PTSD)

• Traumatic Brain Injury (TBI)

Page 4: PTSD and Other Invisible Wounds affecting our Service

How Common is PTSD?

• Affects 7% of Americans

• 4% adult males

• 10% adult females

• Percentage is twice as high in military service members and veterans (14%)

0

2

4

6

8

10

12

14

16

PTSD Prevalence

Males

Females

GeneralPopulation

ServiceMembers &Veterans

Page 5: PTSD and Other Invisible Wounds affecting our Service

Prevalence of Trauma and PTSD in the US

60.7

51.2

8.1

20.4

91.9

79.6

0

10

20

30

40

50

60

70

80

90

100

Men Women

Percen

t (%

)

Trauma

PTSD

Kessler (1995)

Page 6: PTSD and Other Invisible Wounds affecting our Service

Rate of PTSD is Influenced

by the Type of Trauma

Kessler (1995)

0

10

20

30

40

50

60

Disaster Accident Assault Molestation Combat* Rape

Per

cen

t (%

)

Trauma PTSD

Page 7: PTSD and Other Invisible Wounds affecting our Service

Rate of PTSD is Influenced

by the Type of Trauma

0

10

20

30

40

50

60

70

80

90

No Rape Rape

- Threat, - Injury

- Threat, + Injury

+ Threat, - Injury

+ Threat, + Injury

Kilpatrick et al., (1989)

Percentage of Crime Victim Groups With and Without Rape, Life Threat, and Physical Injury

that Developed Crime-Related PTSD

Page 8: PTSD and Other Invisible Wounds affecting our Service

Who is at Greatest Risk for PTSD?

• Those with most significant or

frequent traumas

• Tip-of-the spear military warriors

• Those in blast explosions

resulting in horrific and mutilating

injuries and death

• Those who experience significant risk of personal injury or

death

• Those who experience things no humans should have to

experience

Page 9: PTSD and Other Invisible Wounds affecting our Service

PTSD, PTS(D), or PTS?

• Former Army Vice Chief of Staff Gen Chiarelli

opposed the term “disorder”

• Suggested calling it posttraumatic stress (PTS)

• Others have suggested using the terms:• Combat stress injury

• Combat and operational stress reaction

• Currently accepted term is PTSD• Important to differentiate PTSD from PTS

• Perhaps most important point is that civilian research

has shown PTSD can be treated into remission and in

most cases there is no relapse

Page 10: PTSD and Other Invisible Wounds affecting our Service

Postdeployment PTSD & PTS

in Ft Hood Soldiers

• N = 1416 Soldiers evaluated postdeployment

• PTSD diagnosis using PCL-M plus DSM-IV-TR algorithm

52%

26%22%

0%

10%

20%

30%

40%

50%

60%

No PTS PTS PTSD

Page 11: PTSD and Other Invisible Wounds affecting our Service

Postdeployment PTSD & PTS

in Ft Hood Soldiers

• N = 1416 Soldiers evaluated postdeployment

• PTSD diagnosis using PCL-M plus DSM-IV-TR algorithm

52%

26%22%

0%

10%

20%

30%

40%

50%

60%

No PTS PTS PTSD

PTS(D)?

Page 12: PTSD and Other Invisible Wounds affecting our Service

Comorbidities of PTSD

• PTSD has many related or comorbid conditions

• Depression

• Sleep Disorders

• Chronic Pain

• Traumatic Brain Injury

• Substance Use Disorders

• Suicide

Page 13: PTSD and Other Invisible Wounds affecting our Service

Need for Military-Relevant

PTSD Research

• U.S. facing potential national health crisis

• Current need for treatment may exceed capacity

• Few studies to guide treatment of PTSD in military

• Medical discharge for post-9/11 veteran for PTSD:

• $500K estimated cost for lifetime disability

• Imperative not to repeat Vietnam scenario

Page 14: PTSD and Other Invisible Wounds affecting our Service

What is the most common

myth about PTSD?

Page 15: PTSD and Other Invisible Wounds affecting our Service

What is the most common

myth about PTSD?

PTSD is a chronic, lifelong

condition that is very

difficult to treat

Page 16: PTSD and Other Invisible Wounds affecting our Service

Institute of Medicine (2008) RAND Report (2008)

Page 17: PTSD and Other Invisible Wounds affecting our Service

Institute of Medicine (2008)

• The committee concludes that the current scientific

evidence for the treatment of PTSD is:

• Sufficient to conclude the efficacy of exposure

therapies

• Inadequate to determine the efficacy of EMDR,

cognitive restructuring, coping skills training, and group

format psychotherapy

• Inadequate to determine the efficacy of PTSD

treatment with pharmacotherapy

Page 18: PTSD and Other Invisible Wounds affecting our Service

Evidence-based Treatment of PTSD in

Civilian Populations

Prolonged Exposure (PE): (Edna Foa, PhD)Involves repeated exposure to:

• Memories of the trauma• Trauma-related situations

Cognitive Processing Therapy (CPT): (Patricia Resick, PhD)

Reduces PTSD symptoms through:• Writing/reading accounts of the trauma• Challenging/modifying trauma-related cognitions

Page 19: PTSD and Other Invisible Wounds affecting our Service

Loss of PTSD Diagnosis in Civilians after Treatment with PE and CPT

0

20

40

60

80

100

Pretreatment 5-Year Follow-Up

Perc

en

t w

ith

PT

SD

Cognitive Processing Therapy (n = 63)

Prolonged Exposure (n = 64)

Resick et al., 2012

Page 20: PTSD and Other Invisible Wounds affecting our Service

Unanswered Questions

• What treatments are most effective for combat- or

deployment-related PTSD in active duty military?

• How must civilian treatments be tailored for military

populations?

• What percentage of service members can remain on

active duty and deploy again after treatment?

• What is the impact of redeployment/re-exposure to

combat trauma after treatment for PTSD?

Page 21: PTSD and Other Invisible Wounds affecting our Service

Unanswered Questions

• What is the impact of comorbid conditions on the

treatment of PTSD and

• TBI

• Insomnia

• Substance Use Disorders

• Chronic Pain

• Suicide Risk

Page 22: PTSD and Other Invisible Wounds affecting our Service

Unanswered Questions

• How does the brain change after effective treatment

for PTSD?

• Are there genetic factors that determine who

develops combat-related PTSD?

• Can PTSD be prevented by using prophylactic

medications?

• What factors are related to risk and resiliency?

Page 23: PTSD and Other Invisible Wounds affecting our Service
Page 24: PTSD and Other Invisible Wounds affecting our Service
Page 25: PTSD and Other Invisible Wounds affecting our Service

www.STRONGSTAR.org

Open treatment studies at:

www.STRONGSTAR.org/treatment

Page 26: PTSD and Other Invisible Wounds affecting our Service

STRONG STAR: South Texas Research Organizational

Network Guiding Studies on Trauma And Resilience

CAP: Consortium to Alleviate PTSD

• Headquartered at UT Health San Antonio

• World’s leading research consortia for diagnosis, prevention &

treatment of combat PTSD and related conditions (sleep

disorders, chronic pain, suicide, TBI, substance use disorders)

• 40 collaborating universities, hospitals, & institutions

• 52 peer-reviewed funded research projects

• 28 active research projects

• 140 collaborating investigators and clinicians

• Over $150 million in peer-reviewed research funding

26

Page 27: PTSD and Other Invisible Wounds affecting our Service

STRONG STAR-CAP

•Vision: To reduce or eliminate combat-

related PTSD in active-duty military and

recently discharged veterans

•Mission: To support multi-disciplinary &

multi-institutional research collaboration with

the synergy to develop new PTSD

prevention & treatment programs that could

not be achieved independently 27

Page 28: PTSD and Other Invisible Wounds affecting our Service

Brief Summary of STRONG STAR Findings

• Resick (2015), Group CPT vs Group PCT for PTSD• PTSD can be effectively treated with group CPT

• Rudd (2015), Brief CBT for Suicide• Suicide attempts reduced by 60%

• Resick (2016), Individual vs Group CPT for PTSD• Individual CPT is more effective than Group CPT

• Taylor (2017), CBTi for insomnia• In-Person CBTi more effective than Web-Based CBTi

• Cigrang (2017), Brief PE in Primary Care• Brief treatment by behavioral consultants is effective

• Foa (2018), Massed vs Spaced PE for PTSD• Both are effective for combat-related PTSD

28

Page 29: PTSD and Other Invisible Wounds affecting our Service

TBI

Page 30: PTSD and Other Invisible Wounds affecting our Service

Traumatic Brain Injury (TBI)

• A traumatically induced structural injury and/or a

physiologic disruption of brain function

• as a result of an external force

• that is indicated by new onset or worsening of

• at least 1 of 5 clinical signs immediately

following the event

Page 31: PTSD and Other Invisible Wounds affecting our Service

VA/DOD Definition of TBI

• At least one of the following clinical signs

immediately following the event:

• Loss of consciousness

• Loss of memory for events immediately before

or after injury

• Alteration in mental state at the time of injury

• Neurologic deficits

• Intracranial lesion

Page 32: PTSD and Other Invisible Wounds affecting our Service

How is TBI Diagnosed?

• Interview

• Physical Examination

• Neurobehavioral Symptom Inventory

• Notes:

• TBI is a historical event

• It is most often retrospectively diagnosed

Page 33: PTSD and Other Invisible Wounds affecting our Service

Severity Classification of TBI

Criteria Mild Moderate Severe

LOC 0 - 30 mins 31 mins - 24 hrs >24 hours

AOC Moment - 24 hrs >24 hours. Severity based on

other criteria

PTA 0 - 1 Day 2 – 7 Days >7 Days

GCS 13 - 15 9 – 12 <9

Structural

Imaging

Normal Normal or

Abnormal

Normal or

Abnormal

Page 34: PTSD and Other Invisible Wounds affecting our Service

How is TBI Treated?

• Mild TBI (concussion)

• Over 30 randomized clinical trials have been

conducted

• No evidence-based treatments have been

identified

• Primary approaches:

• Rest and inactivity

• Clinical Symptom Management

Page 35: PTSD and Other Invisible Wounds affecting our Service

TBI Diagnostic Challenges

• Diagnostic criteria are based largely on patient

self-report, particularly for mild TBI

• Possible threats to diagnostic accuracy:

• Recall bias

• Cognitive difficulties

• Overlap of symptoms in co-morbid conditions

• Other factors

Page 36: PTSD and Other Invisible Wounds affecting our Service

TBI and PTSD Symptom Overlap

TBI• Insomnia

• Memory Problems

• Poor concentration

• Depression

• Anxiety

• Irritability

• Headache

• Dizziness

• Fatigue

• Noise/light intolerance

PTSD• Insomnia

• Memory problems

• Poor concentration

• Depression

• Anxiety

• Irritability

• Re-experiencing

• Avoidance

• Emotional numbing

Page 37: PTSD and Other Invisible Wounds affecting our Service

In Summary

Signature Injuries of OIF/OEF/OND

PTSD

TBI

Burns

Amputations

Page 38: PTSD and Other Invisible Wounds affecting our Service

THE Signature Injury of

OIF/OEF/OND

Blast Trauma

Page 39: PTSD and Other Invisible Wounds affecting our Service

The Salute Seen Around

the World(1:36)

Page 41: PTSD and Other Invisible Wounds affecting our Service

Contact

Alan L. Peterson, PhD

University of Texas Health Science Center at San

Antonio

Office Phone: (210) 562-6700

Cell Phone: (210) 508-5428

Email: [email protected]

Page 42: PTSD and Other Invisible Wounds affecting our Service