Why Choose Transderma?

Trusted Advanced-Technology combined with High-Quality Ingredients yields Superior Products.

Transderma adheres to high cGMP manufacturing standards in order to create consistent, high-quality products with superior effi cacy and safety profi les. Specially selected ingredients are used for the prevention of microbiological or fungal contami-nation, while refi ned-oils maximize delivery potential of active ingredients. In particular, the PLO product line combines the delivery intelligence of traditional lecithin organogels yet main-tains the cosmetic appeal of an elegant, yet effective, robust transdermal gel.

Transderma also offers a wide variety of other vehicles for professional compounding needs.

PLO Gels & Kits

B Y T R A N S D E R M A P H A R M A C E U T I C A L S I N C .©2008 Transderma Pharmaceuticals Inc.TRANS-05-001

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Corporate Head Offi ce2400 Canoe Ave. Coquitlam, BC Canada V3K 6C2

Email. info@transderma.com Web. www.transderma.com

INNOVATORS IN COMPOUNDING

For Information on ordering please contact Xenex Labs.

Toll Free: 1.800.663.1002 Fax: 1.888.552.4993

PLO Kits

Tranderma PLO Kits are conveniently packed with three key com-ponents in separate bottles: Organic phase, Hydrophillic phase, and Ethoxy Diglycol solvent. When incorporated with the active ingredient in the desired proportions, the result is a unique PLO topical base that is tailored to patients’ requirement of drug con-centration and degree of moisturization.

The new PLO Kit now contains a Hydrophillic phase with 30% pluronic. This enables the pharmacists to produce a more robust fi nal gel product and uniquely deliver more active drug to the desired area.

A Matter of Choice – The question of choosing between the use of the PLO Premixed Gel or the PLO Kit is a matter of personal preference. With the versatile PLO Kit, the fi nished product can be customized to meet the unique compounding needs of the prescription, yet is conveniently packed for ease of preparation by the pharmacist.

Provides Greater Compounding Flexibility

Customize Your Delivery

Vehicle!

AVAILABLE IN 100 ML KITS, 500 ML KITS AND 1000 ML KITS. ALSO AVAILABLE SEPARATELYIN 500 ML SIZES OF HYDROPHILLIC AND IN500 ML SIZES ORGANIC

Customize Your Delivery

Vehicle!

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PLO Premixed GelsTransPen Cream

Want to combine effective dermal delivery of actives while ensuring high patient-acceptance and compliance? Are your patients complaining of unappealing and sticky topically compounded therapies?

TransPen Cream is an ideal choice in a penetrating and vanishing compounding cream. TransPen is the newest non-medicated compounding base from the Transderma line of elegant bases. TransPen is a moisturizing oil-in-water emulsion that is specially formulated for its vanishing and penetrating properties. Transpen is used to produce a clean, non-tacky and silky fi nish to the skin including penetrating enhancing ingredients that add extra hydration and emulsifying lubricating properties.

Pharmacists will fi nd many applications for this penetrating and vanishing cream for HRT compounds such as Progesterone, Tri-est and Bi-est, Dermatological compounds such as Tretinoin and Hydroquinone and Pain Compounds such as Clonidine, Gabapentin, Piroxicam and many other actives that can be safely and effectively incorporated into TransPen.

Transderma PLO (Premium Lecithin Organogel) represents the next generation of PLO gels. Transderma PLO Premixed Gels are ready-to-use intradermal bases. Intradermal bases are the mainstay of Local Enhanced Transdermal Delivery. LETD, for example, is an effective, safe alternative to oral NSAID use for local tissue infl am-mation. Transderma PLO Gels are specially made to target local tissues and achieve local therapeutic drug-levels while minimizing blood-level related toxicities.

PLO gels have already gained acceptance as the intradermal ve-hicle of choice for a variety of drugs including diclofenac, ibuprofen, ketoprofen, and progesterone. The benefi ts of Transderma PLO Gels include:

1. High Penetrating-Power – Achieve high, therapeutic tissue-levels while reducing blood-level related side effects2. Ready-to-Use – Reduce compounding time 3. Improved Stability – Remain uniform and appealing for longer periods of time and under different storage conditions4. No skin-irritating pluronic surfactant – Avoid local skin-intolerance reactions5. Cosmetically-Pleasing – a non-greasy, non-tacky, soothing skin moisturizer

DermalPenetrating

Power

NEW!

Easy & Ready to UseThe ultimate penetrating & vanishingcompounding cream

Active Drug Strength Range

Diclofenac 2-5%Ibuprofen 10-20%Ketoprofen 5-15%Progesterone 1%

AVAILABLE IN 100GM AND 500GM SIZES

DermalPenetrating

Power

NEW!

PLO Ultramax Gel

Since transdermal delivery of drugs is effectively used for both acute and chronic therapy, vehicles must meet the demand of varying percentages of actives, and also the pharmacists’ demands for time-effi cient and uniform compounding. There is a trend toward accommodating ever-increasing percentages of active drugs beyond the range of basic PLO gels.

Transderma PLO (Pluronic Lecithin Organogel) Ultramax Gel answers the need for ready-to-use vehicles to incorporate higher percentages of active drugs, without disturbing the elegant na-ture or the effi cacy of the gel.

In addition to aforementioned benefi ts of the Transderma PLO Premixed Gels, Ultramax can be depended upon for its powerful uptake capacity of the following active drugs:

For Increased Amounts of Actives

10%Diclofenac

Active Drug Strength Range

Diclofenac 5-10%

Ibuprofen 10-25%

Ketoprofen 5-20%

Progesterone 5%

AVAILABLE IN 100GMAND 500 GM SIZES

AVAILABLE IN 100GMAND 500GM SIZES

Trusted Advanced-Technology combined with High-Quality Ingredients yields Superior Products.

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