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7/24/2019 Protein Paper Review
1/1
CHEM-GA 3010 Fall 2015Review Assignment
Reviewer Name: Jonathan OswaldManuscrit title: Unraveling the Mechanism of Protein Disaggregation Through
a ClpB-DnaK nteraction
!lease ran" t#e manuscrit acc$r%ing t$ t#e criteria &el$w 'mar" wit# an ()* !lease ta"e int$acc$unt t#at articles s#$ul% re$rt unu&lis#e% w$r" t#at %escri&es new insig#ts an%+$rc$ncetual &rea"t#r$ug#s $, aeal t$ t#e rea%ers#i $, t#e $urnal
!ot suita"le for pu"licationin chosen #ournal
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,re the conclusions adeuatel* supported"* the data.
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,re the literature references appropriateand correct.
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Do the contents #ustif* the length of themanuscript.
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C$mments t$ t#e aut#$rs
+our paper does a thorough #o" investigating the interactions of the proteins of1protein disaggregation23 using a revolutionar* !M/ method that allows fordetection of meth*l groups of particular amino acids4 found m*self wonderingwhat the true significance of this information was5 *ou presented the importanceof this understanding in a wa* that suggested have a thorough understanding of
this topic alread*2 forgetting to highlight the grand scheme importance4 thin6what is highlighted is the importance of this !M/ techniue2 which can "e usedto stud* protein-protein interactions in a new2 convenient manner4