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PROTEIN CATALOG 2016 NEXGEN Biotechnologies, Inc. All Rights Reserved.

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Page 1: PROTEIN CATALOG -   · PDF fileThe Next Generation of Biotechnology. SPIDER TOXIN ... sh-PDGF-BB sh-VEGF121 sh-TGF- ... NG-SY-47 NG-PV-MSP CONTENTS SPIDER

PROTEINCATALOG ⓒ 2016 NEXGEN Biotechnologies, Inc. All Rights Reserved.

Page 2: PROTEIN CATALOG -   · PDF fileThe Next Generation of Biotechnology. SPIDER TOXIN ... sh-PDGF-BB sh-VEGF121 sh-TGF- ... NG-SY-47 NG-PV-MSP CONTENTS SPIDER

PIDER nexgenbiotech.com

FIBER PROTEIN

Page 3: PROTEIN CATALOG -   · PDF fileThe Next Generation of Biotechnology. SPIDER TOXIN ... sh-PDGF-BB sh-VEGF121 sh-TGF- ... NG-SY-47 NG-PV-MSP CONTENTS SPIDER

NEXGEN Story

NEXGEN Biotechnologies, Inc., has been 18 years in Korea, specialties on research and de-velopment of recombinant proteins to be used for medical/skincare industry. NEXGEN Biotechnologies, Inc., has been awarded “Korea’s 10 New Technologies” by the Ministry of Commerce, Industry and Energy in Korea(present, Ministry of Knowledge Eco-nomy) in 2005, and appointed as a “National Research Laboratory” in 2006 as well.

NEXGEN Biotechnologies, Inc., has been producing over 50 kinds of special proteins as well as distinctive skincare products “BIOMETICS” which are different from cosmetics.

NEXGEN®

The Next Generation of Biotechnology

Page 4: PROTEIN CATALOG -   · PDF fileThe Next Generation of Biotechnology. SPIDER TOXIN ... sh-PDGF-BB sh-VEGF121 sh-TGF- ... NG-SY-47 NG-PV-MSP CONTENTS SPIDER

SPIDERTOXINPROTEIN

© 2016 NEXGEN Biotechnologies, Inc. All Rights Reserved.

Page 5: PROTEIN CATALOG -   · PDF fileThe Next Generation of Biotechnology. SPIDER TOXIN ... sh-PDGF-BB sh-VEGF121 sh-TGF- ... NG-SY-47 NG-PV-MSP CONTENTS SPIDER

HSP20

H10GD

GDH10

PeptideStefanine

Danieline

Tgenine

Dollarine

ETeline

Tobosmoline

Btale 1

Btale 2

Scoline

Cobrine

Growth Factors/Otherssh-EGF

sh-aFGF

sh-bFGF

sh-IGF-1

sh-IGF-2

sh-KGF

sh-bNGF

sh-CTGF

sh-GD11

sh-GH

SkincareSVP

EGF-SV

BTAL

BTAL-EGF

TRX-CLT

EGF-CLT

SFP

GH-SFP

EGF-SFP

SFP-EGF

GFP(plant-made)

rGFP

EGF-GFP

GFP-EGF

EGF-GH

GH-EGF

GH-EGF-IGF-1

AFPSR

EGF-AFPOP

EGF-AFPSR

HAS3

Hag Fiber

LIN

CHI6

HSP10

sh-IL-2

sh-NOG

sh-PDGF-BB

sh-VEGF121

sh-TGF-α

sh-TGF-β

sh-SCF

sh-THY-b4

sh-PRX1

sh-PRX2

sh-SOD

sh-TRX

Antigens for DiagnosticsNG-HIV-124

NG-HIV-141

NG-HIV-1120

NG-HIV-236

NG-PV-CSP

NG-TB-16

NG-TB-35

NG-TB-85

NG-SY-15

NG-SY-17

NG-SY-47

NG-PV-MSP

CONTENTS

SPIDERTOXINPROTEIN

© 2016 NEXGEN Biotechnologies, Inc. All Rights Reserved.

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Page 6: PROTEIN CATALOG -   · PDF fileThe Next Generation of Biotechnology. SPIDER TOXIN ... sh-PDGF-BB sh-VEGF121 sh-TGF- ... NG-SY-47 NG-PV-MSP CONTENTS SPIDER

·SVP·EGF-SV·BTAL·BTAL-EGF·TRX-CLT·EGF-CLT·SFP·GH-SFP·EGF-SFP·SFP-EGF·GFP(plant-made)·rGFP·EGF-GFP·GFP-EGF

·EGF-GH·GH-EGF·GH-EGF-IGF-1·AFPSR·EGF-AFPOP·EGF-AFPSR·HAS3·Hag Fiber·LIN·CHI6·HSP10·HSP20·H10GD·GDH10

Skincare

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7

·Reduces and prevent wrinkles.

SVP

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-SV concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

The anti-radical activity of NEX-SV protein was determined by the DPPH method.

Tertiary Structure of NEX-SV

Effect on Proliferation of HDFa

Anti-oxidant activity

Features

Trade Name NEX-SV

INCI Name sr-Pectobacterium Polypeptide-1 Arginyl sr-Spider Oligopeptide-1 Dipeptide-19 Hexapeptide-40

CAS # None

Source Escherichia coli

Amino Acid 79

Molecular Weight (kDa) 8.7

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-SV

Application Anti-Wrinkle

Control 0.02 ppm 0.2 ppm

Recombinant Spider Venom Protein

Skincare

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Skincare

The anti-radical activity of NEX-ESV protein was determined by the DPPH method.

Anti-oxidant activity

EGF-SV

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-ESV concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-ESV

Effect on Proliferation of HDFa

Features

Trade Name NEX-ESV

INCI Name sh-Oligopeptide-1 Alanyl sr-Spider Oligopeptide-1

CAS # None

Source Escherichia coli

Amino Acid 103

Molecular Weight (kDa) 11.7

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-ESV

Application Anti-Wrinkle·Skin-Lifting

Control 0.02 ppm 0.2 ppm

Human Epidermal Growth Factor - Spider Venom Hybrid Protein

·Reduces and prevent wrinkles.·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Improves the appearance of age spots.·Reduces pigmentation and skin irregularities.·Improves the texture of the skin and its elasticity.

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BTAL

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-BTAL concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-BTAL

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Botulinum Neurotoxin Type A Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

Trade Name NEX-BTAL

INCI Name In Progress

CAS # None

Source Escherichia coli

Amino Acid 448

Molecular Weight (kDa) 51.3

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-BTAL

Application Skin-Lifting

The anti-radical activity of NEX-BTAL pro-tein was determined by the DPPH method.

Anti-oxidant activity

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Skincare

BTAL-EGF

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-BTALE concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-BTALE

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Botulinum Neurotoxin Type A Protein - Human Epidermal Growth Factor Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

Trade Name NEX-BTALE

INCI Name sr-Clostridium Botulinum Polypeptide-1 sh-Oligopeptide-1

CAS # None

Source Escherichia coli

Amino Acid 502

Molecular Weight (kDa) 57.6

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-BTALE

Application Skin-Lifting· Healing of Wounds

The anti-radical activity of NEX-BTALE pro-tein was determined by the DPPH method.

Anti-oxidant activity

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TRX-CLT

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-TCT concen-tration of 0, 0.02, 0.2, 2 ppm in HDFa cell.

Tertiary Structure of NEX-TCT

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Human Thioredoxin - Chlorotoxin Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Reduces pigmentation and skin irregularities.

Trade Name NEX-TCT

INCI Name sh-Polypeptide-2 sr-Egyptian Scorpion Oligopeptide-1

CAS # None

Source Escherichia coli

Amino Acid 141

Molecular Weight (kDa) 15.7

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-TCT

Application Anti-Wrinkle· Skin-Lifting· Anti-Aging

The anti-radical activity of NEX-TCT protein was determined by the DPPH method.

Anti-oxidant activity

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Skincare

Trade Name NEX-ECT

INCI Name sh-Oligopeptide-1 sr-Egyptian Scorpion Oligopeptide-1

CAS # None

Source Escherichia coli

Amino Acid 90

Molecular Weight (kDa) 10.3

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-ECT

Application Anti-Wrinkle· Skin-Lifting

EGF-CLT

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-ECT concentra-tion of 0, 0.02, 0.2, 2 ppm in HDFa cell.

Tertiary Structure of NEX-ECT

Effect on Proliferation of HDFa

Features

Human Epidermal Growth Factor - Chlorotoxin Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.

The anti-radical activity of NEX-ECT protein was determined by the DPPH method.

Anti-oxidant activity

Control 0.02 ppm 0.2 ppm 2 ppm

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Trade Name NEX-SFP

INCI NameTetrapeptide-39 Hexapeptide-40 Nonapeptide-20 r-Spider Polypeptide-3 Decapeptide-30

CAS # 147883-43-0

Source Escherichia coli

Amino Acid 134

Molecular Weight (kDa) 11.2

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-SFP

Application Anti-Wrinkle

SFPTertiary Structure of NEX-SFP

Features

Spider Fiber Protein

·Improves the texture of the skin and its elasticity.

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Skincare

Trade Name NEX-GS

INCI NameMethionyl sh-Polypeptide-7 Dipeptide-19 sr-Spider Polypeptide-4 Hexapeptide-40

CAS # None

Source Escherichia coli

Amino Acid 325

Molecular Weight (kDa) 33.3

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-GS

Application Anti-Aging·Anti-Wrinkle·Wound healing

GH-SFP

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-GS concentra-tion of 0, 0.01, 0.1 ppm in HDFa cell.

Tertiary Structure of NEX-GS

Effect on Proliferation of HDFa

Thermal stability

Features

Control 0.01 ppm 0.1 ppm

Human Growth Hormone - Spider Fiber Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Improves the appearance of age spots.·Reduces pigmentation and skin irregularities.·Improves the texture of the skin and its elasticity.

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Trade Name NEX-ES

INCI Namesh-Oligopeptide-1 Tripeptide-58 Hexapeptide-40 Decapeptide-41 sr-Spider Polypeptide-3

CAS # None

Source Escherichia coli

Amino Acid 187

Molecular Weight (kDa) 17.4

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-ES

Application Anti-Wrinkle·Skin-Lifting·Wound healing·Anti-Aging

EGF-SFP

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-ES concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-ES

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Human Epidermal Growth Factor - Spider Fiber Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Improves the appearance of age spots.·Reduces pigmentation and skin irregularities.·Improves the texture of the skin and its elasticity.

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Skincare

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-SE concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

Control 0.02 ppm 0.2 ppm

Trade Name NEX-SE

INCI Name In Progress

CAS # None

Source Escherichia coli

Amino Acid 187

Molecular Weight (kDa) 17.4

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-SE

Application Anti-Wrinkle·Skin-Lifting·Wound healing·Anti-Aging

SFP-EGFTertiary Structure of NEX-SE

Effect on Proliferation of HDFa

Features

Spider Fiber Protein - Human Epidemal Growth Factor Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Improves the appearance of age spots.·Reduces pigmentation and skin irregularities.·Improves the texture of the skin and its elasticity.

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Trade Name NEX-GFP

INCI Name Nicotiana benthamiana r-Jellyfish Polypeptide-1

CAS # 147336-22-9

Source Nicotiana benthamiana

Amino Acid 262

Molecular Weight (kDa) 29.5

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-GFP

Application Anti-Oxidant

GFP(plant-made)

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-GFP concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-GFP

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Green Fluorescent Protein, From Plant

·Anti-oxidant that reduces free radicals and inhibits the aged skin cells.·Provides a gorgeous up lifted complexion by reinforcing skin’s defenses.·Reduces and prevents lines and wrinkles by actively generating new skin cells.

The anti-radical activity of NEX-GFP protein was determined by the DPPH method.

Anti-oxidant activity

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Skincare

Trade Name NEX-rGFP

INCI Name sr-Jellyfish Polypeptide-1

CAS # 147336-22-9

Source Escherichia coli

Amino Acid 238

Molecular Weight (kDa) 26.9

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-GFP

Application Anti-Oxidant

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-rGFP concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Control 0.02 ppm 0.2 ppm

rGFPTertiary Structure of NEX-rGFP

Effect on Proliferation of HDFa

Features

Recombinant Green Fluorescent Protein, From E. coli

·Anti-oxidant that reduces free radicals and inhibits the aged skin cells.·Provides a gorgeous up lifted complexion by reinforcing skin’s defenses.·Reduces and prevents lines and wrinkles by actively generating new skin cells.

The anti-radical activity of NEX-rGFP protein was determined by the DPPH method.

Anti-oxidant activity

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Trade Name NEX-EGFGFP

INCI Name Methionyl sh-Oligopeptide-1 sr-Jellyfish Polypeptide-1

CAS # None

Source Escherichia coli

Amino Acid 291

Molecular Weight (kDa) 33.2

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-EGFGFP

Application Anti-Wrinkle·Skin-Lifting·Wound healing·Anti-Oxidant

EGF-GFP

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-EGFGFP con-centration of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-EGFGFP

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Human Epidermal Growth Factor - Green Fluorescent Protein Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Improves the appearance of age spots.·Reduces pigmentation and skin irregularities.·Improves the texture of the skin and its elasticity.·Anti-oxidant that reduces free radicals and inhibits the aged skin cells.·Provides a gorgeous up lifted complexion by reinforcing skin’s defenses.

The anti-radical activity of NEX-EGFGFP pro-tein was determined by the DPPH method.

Anti-oxidant activity

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Skincare

Trade Name NEX-GFPEGF

INCI Name sr-Jellyfish Polypeptide-1 sh-Oligopeptide-1

CAS # None

Source Escherichia coli

Amino Acid 291

Molecular Weight (kDa) 33.2

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-GFPEGF

Application Anti-Wrinkle·Skin-Lifting·Wound healing·Anti-Oxidant

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-GFPEGF con-centration of 0, 0.02, 0.2 ppm in HDFa cell.

Control 0.02 ppm 0.2 ppm

GFP-EGFTertiary Structure of NEX-GFPEGF

Effect on Proliferation of HDFa

Features

Green Fluorescent Protein - Human Epidermal Growth Factor Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Improves the appearance of age spots.·Reduces pigmentation and skin irregularities.·Improves the texture of the skin and its elasticity.·Anti-oxidant that reduces free radicals and inhibits the aged skin cells.·Provides a gorgeous up lifted complexion by reinforcing skin’s defenses.

The anti-radical activity of NEX-GFPEGF pro-tein was determined by the DPPH method.

Anti-oxidant activity

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Trade Name NEX-EG

INCI Name sh-Oligopeptide-1 sh-Polypeptide-7 Dipeptide-19

CAS # None

Source Escherichia coli

Amino Acid 244

Molecular Weight (kDa) 28.3

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-EG

Application Anti-Wrinkle·Skin-Lifting·Wound healing·Anti-Aging

EGF-GH

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-EG concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-EG

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Human Epidermal Growth Factor - Growth Hormone Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Improves the appearance of age spots.·Reduces pigmentation and skin irregularities.·Improves the texture of the skin and its elasticity.·Woud healing. ·Growth support for skin cells as like IGF.·Support young and healthy skin.

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Skincare

Trade Name NEX-GE

INCI Name sh-Polypeptide-7 sh-Oligopeptide-1

CAS # None

Source Escherichia coli

Amino Acid 244

Molecular Weight (kDa) 28.3

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-GE

Application Anti-Wrinkle·Skin-Lifting·Wound healing·Anti-Aging

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-GE concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

Control 0.02 ppm 0.2 ppm

GH-EGFTertiary Structure of NEX-GE

Effect on Proliferation of HDFa

Features

Human Growth Hormone - Epidermal Growth Factor Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal and epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Improves the appearance of age spots.·Reduces pigmentation and skin irregularities.·Improves the texture of the skin and its elasticity.·Woud healing.·Growth support for skin cells as like IGF.·Support young and healthy skin.

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Trade Name NEX-GEI

INCI NameMethionyl sh-Polypeptide-7 sh-Oligopeptide-1 sh-Oligopeptide-2

CAS # None

Source Escherichia coli

Amino Acid 315

Molecular Weight (kDa) 36.1

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-GEI

Application Anti-Wrinkle·Anti-Aging· Skin-Lifting· Healing of Wounds

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-GEI concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

Control 0.02 ppm 0.2 ppm

GH-EGF-IGF-1Tertiary Structure of NEX-GEI

Effect on Proliferation of HDFa

Features

Human Growth Hormone - Epidermal Growth Factor - Insulin Like Growth Factor 1, Human Epidermal, Triple Fusion Hybrid Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Growth support for skin cells as like IGF.·Support young and healthy skin.·Improves the appearance of age spots.·Reduces pigmentation and skin irregularities.·Improves the texture of the skin and its elasticity.·Growth support for skin with EGF.·Restore redued activity with age.

The anti-radical activity of NEX-GEI protein was determined by the DPPH method.

Anti-oxidant activity

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Skincare

Trade Name NEX-AFPSR

INCI Name sr-Sea Raven Polypeptide-1

CAS # None

Source Escherichia coli

Amino Acid 129

Molecular Weight (kDa) 14

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-AFPSR

Application Cell proliferation

AFPSRTertiary Structure of NEX-AFPSR

Features

Recombinant Anti-freezing Protein(Sea Raven)

·Stimulates the proliferation of a wide range of epidermal cells.

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Trade Name NEX-EAFPOP

INCI Namesh-Oligopeptide-1 sr-Ocean Pout Oligopeptide-1 Dipeptide-39

CAS # None

Source Escherichia coli

Amino Acid 118

Molecular Weight (kDa) 13.1

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-EAFPOP

Application Cell proliferation

EGF-AFPOP

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-EAFPOP con-centration of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-EAFPOP

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Human Epidermal Growth Factor - Anti-freezing Protein(Ocean Pout) Hybird Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

The anti-radical activity of NEX-EAFPOP pro-tein was determined by the DPPH method.

Anti-oxidant activity

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26

Skincare

Trade Name NEX-EAFPSR

INCI Name sh-Oligopeptide-1 sr-Sea Raven Polypeptide-1

CAS # None

Source Escherichia coli

Amino Acid 182

Molecular Weight (kDa) 20.2

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-EAFPSR

Application Cell proliferation

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-EAFPSR con-centration of 0, 0.02, 0.2 ppm in HDFa cell.

Control 0.02 ppm 0.2 ppm

EGF-AFPSRTertiary Structure of NEX-EAFPSR

Effect on Proliferation of HDFa

Features

Human Epidermal Growth Factor - Anti-freezing Protein(Sea Raven) Hybird Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

The anti-radical activity of NEX-EAFPSR pro-tein was determined by the DPPH method.

Anti-oxidant activity

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Trade Name NEX-HAS3

INCI Name sh-Polypeptide-91

CAS # 39346-43-5

Source Escherichia coli

Amino Acid 553

Molecular Weight (kDa) 63

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-HAS3

Application Anti-Wrinkle·Anti-Aging·Wound healing

HAS3

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-HAS3 concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-HAS3

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Hyaluronic Acid Synthase 3

·Reduces and prevent wrinkles.·Hydrating and moisturising the skin from the inside and with this helps to smooth out wrinkles.·Promote healing and to fight inflammatory conditions of the skin.·Supples smooth skin.

The anti-radical activity of NEX-HAS3 pro-tein was determined by the DPPH method.

Anti-oxidant activity

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Skincare

Trade Name NEX-Hag Fiber

INCI Name sr-Hagfish Polypeptide-1

CAS # None

Source Escherichia coli

Amino Acid 643

Molecular Weight (kDa) 66.7

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-Hag Fiber

Application Anti-Wrinkle

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Hag Fiber con-centration of 0, 0.02, 0.2 ppm in HDFa cell.

Control 0.02 ppm 0.2 ppm

Hag FiberTertiary Structure of NEX-Hag Fiber

Effect on Proliferation of HDFa

Features

Recombinant Hagfish Fiber

·Improves the texture of the skin and its elasticity.

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Trade Name NEX-LIN

INCI Name sh-Polypeptide-97

CAS # None

Source Escherichia coli

Amino Acid 217

Molecular Weight (kDa) 23.8

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-LIN

Application Anti-Wrinkle·Skin-Lifting

LIN

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-LIN concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-LIN

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Synthetic Human LIN Protein

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces pigmentation and skin irregularities.·Improves the texture of the skin and its elasticity.

The anti-radical activity of NEX-LIN protein was determined by the DPPH method.

Anti-oxidant activity

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Skincare

Trade Name NEX-CHI6

INCI Name sr-Oligopeptide-1

CAS # None

Source Escherichia coli

Amino Acid 187

Molecular Weight (kDa) 17.4

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-CHI6

Application Skin-Lifting·Healing of Wounds

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-CHI6 concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Control 0.02 ppm 0.2 ppm

CHI6Tertiary Structure of NEX-CHI6

Effect on Proliferation of HDFa

Features

Novel Chimeric Polypeptide

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

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The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-HSP20 concen-tration of 0, 0.02, 0.2, 2, 20 ppm in HDFa cell.

The anti-radical activity of NEX-HSP10 pro-tein was determined by the DPPH method.

Anti-oxidant activity

Control 0.02 ppm 0.2 ppm 2 ppm 20 ppm

Effect on Proliferation of HDFa

Trade Name NEX-HSP10

INCI Name In progress

CAS # None

Source Escherichia coli

Amino Acid 102

Molecular Weight (kDa) 10.9

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-HSP10

Application Anti-Wrinkle·Wound healing

HSP10Tertiary Structure of NEX-HSP10

Features

Heat Shock Protein 10

·Stimulates the proliferation of a wide range of epidermal and epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

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Skincare

Trade Name NEX-HSP20

INCI Name In progress

CAS # None

Source Escherichia coli

Amino Acid 182

Molecular Weight (kDa) 20

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-HSP20

Application Anti-Wrinkle · Wound healing

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-HSP20 concen-tration of 0, 0.02, 0.2, 2, 20 ppm in HDFa cell.

Control 0.02 ppm 0.2 ppm 2 ppm 20 ppm

HSP20Tertiary Structure of NEX-HSP20

Effect on Proliferation of HDFa

Features

Heat Shock Protein 20

·Stimulates the proliferation of a wide range of epidermal and epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

The anti-radical activity of NEX-HSP20 pro-tein was determined by the DPPH method.

Anti-oxidant activity

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The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-H10GD con-centration of 0, 0.02, 0.2 ppm in HDFa cell.

Effect on Proliferation of HDFaControl 0.02 ppm 0.2 ppm

Trade Name NEX-H10GD

INCI Name In progress

CAS # None

Source Escherichia coli

Amino Acid 219

Molecular Weight (kDa) 24.4

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-H10GD

Application Anti-Wrinkle·Wound healing

H10GDTertiary Structure of NEX-H10GD

Features

Modified Growth differentiation factor 11(H10- GDF11 Hybrid Protein)

·Stimulates the proliferation of a wide range of epidermal and epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

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Skincare

Trade Name NEX-GDH10

INCI Name In progress

CAS # None

Source Escherichia coli

Amino Acid 219

Molecular Weight (kDa) 24.4

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-GDH10

Application Anti-Wrinkle·Wound healing

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-GDH10 con-centration of 0, 0.02, 0.2 ppm in HDFa cell.

Control 0.02 ppm 0.2 ppm

GDH10Tertiary Structure of NEX-GDH10

Effect on Proliferation of HDFa

Features

Modified Growth differentiation factor 11(GDF11-H10 Hybrid Protein)

·Stimulates the proliferation of a wide range of epidermal and epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

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Peptide·Stefanine·Danieline·Tgenine·Dollarine·ETeline

·Tobosmoline·Btale 1·Btale 2·Scoline·Cobrine

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Peptide

Trade Name NEX-Stefanine

INCI Name Arginyl sh-Pentapeptide-7

CAS # None

Source Synthesized peptide

Amino Acid 6

Molecular Weight (Da) 734.8

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-Stefanine

Application Cell proliferation

Stefanine

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Stefanine con-centration of 0, 300, 600 ppm in HDFa cell.

Tertiary Structure of NEX-Stefanine

Effect on Proliferation of HDFa

Features

Control 300 ppm 600 ppm

Hexapeptide

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

The anti-radical activity of NEX-Stefan-ine protein was determined by the DPPH method.

Anti-oxidant activity

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Trade Name NEX-Danieline

INCI Name sh-Octapeptide-2

CAS # None

Source Synthesized peptide

Amino Acid 8

Molecular Weight (Da) 931

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-Danieline

Application Cell proliferation

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Danieline con-centration of 0, 300, 600 ppm in HDFa cell.

Control 300 ppm 600 ppm

DanielineTertiary Structure of NEX-Danieline

Effect on Proliferation of HDFa

Features

Octapeptide

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

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Peptide

Trade Name NEX-Tgenine

INCI Name Octapeptide-32

CAS # None

Source Synthesized peptide

Amino Acid 8

Molecular Weight (Da) 738.7

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-Tgenine

Application Cell proliferation

Tgenine

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Tgenine con-centration of 0, 300, 600 ppm in HDFa cell.

Tertiary Structure of NEX-Tgenine

Effect on Proliferation of HDFa

Features

Control 300 ppm 600 ppm

Octapeptide

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

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Trade Name NEX-Dollarine

INCI Name Hexapeptide-64

CAS # None

Source Synthesized peptide

Amino Acid 6

Molecular Weight (Da) 701.7

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-Dollarine

Application Cell proliferation

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Dollarine con-centration of 0, 300, 600 ppm in HDFa cell.

Control 300 ppm 600 ppm

DollarineTertiary Structure of NEX-Dollarine

Effect on Proliferation of HDFa

Features

Hexapeptide

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

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Peptide

Trade Name NEX-Eteline

INCI Name Pentapeptide-58

CAS # None

Source Synthesized peptide

Amino Acid 5

Molecular Weight (Da) 521.5

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-Eteline

Application Cell proliferation

ETeline

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Eteline concen-tration of 0, 300, 600 ppm in HDFa cell.

Tertiary Structure of NEX-Eteline

Effect on Proliferation of HDFa

Features

Control 300 ppm 600 ppm

Pentapeptide

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

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Trade Name NEX-Tobosmoline

INCI Name Oligopeptide-147

CAS # None

Source Synthesized peptide

Amino Acid 15

Molecular Weight (Da) 1743.8

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-Tobosmoline

Application Cell proliferation

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Tobosmoline concentration of 0, 300, 600 ppm in HDFa cell.

Control 300 ppm 600 ppm

TobosmolineTertiary Structure of NEX-Tobosmoline

Effect on Proliferation of HDFa

Features

Tobosmoline peptide

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

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Peptide

Trade Name NEX-btale 1

INCI Name In Progress

CAS # None

Source Synthesized peptide

Amino Acid 10

Molecular Weight (Da) 1.18

pH 7.2 ± 0.2

Appearance Odorless solution or Powder

PurityGreater than 98% as determined by Analysis by RP-HPLC

Endotoxin Level Less than 0.1 ng/ug of NEX-btale 1

Application Anti-Wrinkle· Wound healing

Btale 1

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Btale 1 concen-tration of 1, 10, 100 ppm in HDFa cell.

Tertiary Structure of NEX-Btale 1

Effect on Proliferation of HDFa

Features

Control 1 ppm 10 ppm 100 ppm

Decapeptide

·Stimulates the proliferation of a wide range of epidermal and epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

The anti-radical activity of NEX-Btale 1 pro-tein was determined by the DPPH method.

Anti-oxidant activity

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Trade Name NEX-btale 2

INCI Name In Progress

CAS # None

Source Synthesized peptide

Amino Acid 10

Molecular Weight (Da) 1.1

pH 7.2 ± 0.2

Appearance Odorless solution or Powder

PurityGreater than 98% as determined by Analysis by RP-HPLC

Endotoxin Level Less than 0.1 ng/ug of NEX-btale 2

Application Anti-Wrinkle· Wound healing

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Btale 2 concen-tration of 1, 10, 100 ppm in HDFa cell.

Features

Control 1 ppm 10 ppm 100 ppm

·Stimulates the proliferation of a wide range of epidermal and epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

Btale 2Tertiary Structure of NEX-Btale 2

Effect on Proliferation of HDFa

Decapeptide

The anti-radical activity of NEX-Btale 2 pro-tein was determined by the DPPH method.

Anti-oxidant activity

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Peptide

Trade Name NEX-Scoline

INCI Name In Progress

CAS # None

Source Synthesized peptide

Amino Acid 10

Molecular Weight (Da) 1.18

pH 7.2 ± 0.2

Appearance Odorless solution or Powder

PurityGreater than 98% as determined by Analysisby RP-HPLC

Endotoxin Level Less than 0.1 ng/ug of NEX-Scoline

Application Anti-Wrinkle

Scoline

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Scoline con-centration of 0, 300, 600 ppm in HDFa cell.

Effect on Proliferation of HDFa

Features

Decapeptide

·Stimulates the proliferation of a wide range of epidermal and epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

The anti-radical activity of NEX-Scoline pro-tein was determined by the DPPH method.

Anti-oxidant activity

Control 300 ppm 600 ppm

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45

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-Cobrine con-centration of 0, 300, 600 ppm in HDFa cell.

Control 300 ppm 600 ppm

Trade Name NEX-Cobrine

INCI Name In Progress

CAS # None

Source Synthesized peptide

Amino Acid 10

Molecular Weight (Da) 1.13

pH 7.2 ± 0.2

Appearance Odorless solution or Powder

PurityGreater than 98% as determined by Analysisby RP-HPLC

Endotoxin Level Less than 0.1 ng/ug of NEX-Cobrine

Application Anti-Wrinkle

Features·Stimulates the proliferation of a wide range of epidermal and epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.

Cobrine

Effect on Proliferation of HDFa

Decapeptide

The anti-radical activity of NEX-Cobrine pro-tein was determined by the DPPH method.

Anti-oxidant activity

Effect on Proliferation of HDFa

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Growth Factors/Others·sh-EGF·sh-aFGF·sh-bFGF·sh-IGF-1·sh-IGF-2·sh-KGF·sh-bNGF·sh-CTGF·sh-GD11·sh-GH·sh-IL-2·sh-NOG·sh-PDGF-BB

·sh-VEGF121·sh-TGF-α·sh-TGF-β·sh-SCF·sh-THY-b4·sh-PRX1·sh-PRX2·sh-SOD·sh-TRX

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sh-EGF

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-hEGF concen-tration of 0, 0.1, 1 ppm in HDFa cell.

Tertiary Structure of NEX-hEGF

Effect on Proliferation of HDFa

Features

Control 0.1 ppm 1 ppm

Synthetic Human Epidermal Growth Factor

·Stimulates the proliferation of a wide range of epidermal and epidermal cells. ·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen. ·Improves the appearance of age spots.·Reduces pigmentation and skin irregularities. ·Improves the texture of the skin and its elasticity.

Trade Name NEX-hEGF

INCI Name sh-Oligopeptide-1

CAS # 62253-63-8

Source Escherichia coli

Amino Acid 53

Molecular Weight (kDa) 6.2

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-hEGF

Application Anti-Wrinkle·Skin-Lifting·Wound healing

Growth Factors/Others

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Growth Factors/Others

Trade Name NEX-aFGF

INCI Name rh-Polypeptide-11

CAS # 106096-92-8

Source Escherichia coli

Amino Acid 140

Molecular Weight (kDa) 15.8

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-aFGF

Application Anti-Aging·Anti-Wrinkle·Anti-Hair Loss·Hair Growth

sh-aFGFTertiary Structure of NEX-aFGF

Features

Synthetic Human Acidic Fibroblast Growth Factor

·Wound healing. ·Restore redued activity with age. ·Stimulates the synthesis of collagen. ·Stimulation on hair fromation and regeneration. ·Support hair follicle cell and growth.

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Trade Name NEX-bFGF

INCI Name rh-Polypeptide-1

CAS # 106096-93-9

Source Escherichia coli

Amino Acid 154

Molecular Weight (kDa) 17.1

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-bFGF

Application Anti-Aging·Anti-Wrinkle·Anti-Hair Loss·Hair Growth

sh-bFGF

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-bFGF concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-bFGF

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Synthetic Human Basic Fibroblast Growth Factor

·Wound healing.·Restore redued activity with age.·Stimulates the synthesis of collagen.·Stimulation on hair fromation and regeneration.·Support hair follicle cell and growth.

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Growth Factors/Others

Trade Name NEX-IGF-1

INCI Name rh-Oligopeptide-2

CAS # 67763-96-6

Source Escherichia coli

Amino Acid 70

Molecular Weight (kDa) 7.6

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-IGF-1

Application Anti-Aging·Anti-Wrinkle

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-IGF-1 concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Effect on Proliferation of HDFaControl 0.02 ppm 0.2 ppm

sh-IGF-1Tertiary Structure of NEX-aFGF

Features

Synthetic Human Insulin Like Growth Factor 1

·Growth support for skin with EGF.·Restore redued activity with age.·Stimulates the synthesis of collagen.·Support young and healthy skin.

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Trade Name NEX-IGF-2

INCI Name rh-Polypeptide-31

CAS # 67763-97-7

Source Escherichia coli

Amino Acid 66

Molecular Weight (kDa) 7.3

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-IGF-2

Application Anti-Aging·Anti-Wrinkle

sh-IGF-2 Tertiary Structure of NEX-IGF-2

Features

Synthetic Human Insulin Like Growth Factor 2

·Growth support for skin with EGF.·Restore redued activity with age.·Stimulates the synthesis of collagen.·Support young and healthy skin.

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Growth Factors/Others

Trade Name NEX-KGF

INCI Name rh-Polypeptide-3

CAS # 148348-15-6

Source Escherichia coli

Amino Acid 163

Molecular Weight (kDa) 18.9

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-KGF

Application Anti-Wrinkle·Skin Firming·Hair Growth

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-KGF concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

Effect on Proliferation of HDFaControl 0.02 ppm 0.2 ppm

sh-KGFTertiary Structure of NEX-KGF

Features

Synthetic Human Keratinocyte Growth Factor

·Reduces and prevents wrinkles by generating new skin cells. ·Refines texture glides effectively and lights up skin.·Follicles to produce strong hair shaft.

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Trade Name NEX-bNGF

INCI Name sh-Polypeptide-14

CAS # 86923-98-0

Source Escherichia coli

Amino Acid 120

Molecular Weight (kDa) 13.5

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-bNGF

Application Anti-Aging·Anti-Wrinkle·Anti-Hair Loss·Hair Growth

sh-bNGF

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-bNGF concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-bNGF

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Synthetic Human Basic Fibroblast Growth Factor

·Restore the reduced activity with age.·Stimulate the collagen synthesis in aged skin.·Wound healing.·Support hair follicle cells and growth.·Stimulate the hair formation and regeneration.

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54

Growth Factors/Others

Trade Name NEX-CTGF

INCI Name Methionyl sh-Polypeptide-93

CAS # None

Source Escherichia coli

Amino Acid 324

Molecular Weight (kDa) 35.6

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-CTGF

Application Anti-Aging·Anti-Wrinkle

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-CTGF concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Effect on Proliferation of HDFaControl 0.02 ppm 0.2 ppm

sh-CTGFTertiary Structure of NEX-CTGF

Features

Synthetic Human Connective Tissue Growth Factor

·Possesses an Insulin-like Growth Factor (IGF)-binding domain.·Restore redued activity with age.·Stimulates the synthesis of collagen.·Support young and healthy skin.

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Trade Name NEX-GD11

INCI Name Methionyl sh-Polypeptide-92

CAS # None

Source Escherichia coli

Amino Acid 109

Molecular Weight (kDa) 12.4

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-GD11

Application Anti-Aging·Anti-Wrinkle

sh-GD11Tertiary Structure of NEX-GD11

Features

Synthetic Human Growth/Differentiation factor 11

·Restore redued activity with age.·Regenerates the skin cell.·Support young and healthy skin.

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Growth Factors/Others

Trade Name NEX-GH

INCI Name rh-Polypeptide-7

CAS # 12629-01-5

Source Escherichia coli

Amino Acid 191

Molecular Weight (kDa) 22.2

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-GH

Application Anti-Wrinkle·Anti-Aging

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-GH concentra-tion of 0, 0.1, 1 ppm in HDFa cell.

Effect on Proliferation of HDFaControl 0.1 ppm 1 ppm

sh-GHTertiary Structure of NEX-GH

Features

Synthetic Human Growth Hormone

·Stimulates the proliferation of a wide range of epidermal cells.·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Woud healing.·Growth support for skin cells as like IGF.·Support young and healthy skin.

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Trade Name NEX-IL-2

INCI Name rh-Polypeptide-25

CAS # 110942-02-04

Source Escherichia coli

Amino Acid 133

Molecular Weight (kDa) 15.4

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-IL-2

Application Anti-Wrinkle·Anti-Aging

sh-IL-2Tertiary Structure of NEX-IL-2

Features

Synthetic Human Interleukin-2

·Reduces and prevent wrinkles by generating new skin cells.·Stimulates the synthesis of collagen.·Support young and healthy skin.

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Growth Factors/Others

Trade Name NEX-NOG

INCI Name rh-Polypeptide-13

CAS # 148294-77-3

Source Escherichia coli

Amino Acid 204

Molecular Weight (kDa) 23

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-NOG

Application Hair Growth·Improving skin conditions

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-NOG concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Effect on Proliferation of HDFaControl 0.02 ppm 0.2 ppm

sh-NOGTertiary Structure of NEX-NOG

Features

Synthetic Human Noggin

·Inhibits the activity of bone morphogenetic protein 4 (BMP4).·Stimulates the hair growth.

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Trade Name NEX-PDGF-BB

INCI Name rh-Polypeptide-59

CAS # 143784-00-03

Source Escherichia coli

Amino Acid 109

Molecular Weight (kDa) 12.1

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-PDGF-BB

Application Anti-Aging·Wound Healing

sh-PDGF-BBTertiary Structure of NEX-PDGF-BB

Features

Synthetic Human Platelet-Derived Growth Factor BB

·Promotes the growth of skin.·Promotes the wound healing.

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Growth Factors/Others

Trade Name NEX-VEGF121

INCI Name rh-Polypeptide-9

CAS # None

Source Escherichia coli

Amino Acid 121

Molecular Weight (kDa) 14.05

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-VEGF121

Application Hair Growth

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-VEGF121 con-centration of 0, 0.02, 0.2 ppm in HDFa cell.

Effect on Proliferation of HDFaControl 0.02 ppm 0.2 ppm

sh-VEGF121Tertiary Structure of NEX-VEGF121

Features

Synthetic Human Vascular Endothelial Cell Growth Factor

·Hair growth stimulation through the facilitation of nutrient feeding to hair follicle.·Induces angiogenesis.

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Trade Name NEX-TGF-α

INCI Name rh-Polypeptide-19

CAS # 105186-99-0

Source Escherichia coli

Amino Acid 50

Molecular Weight (kDa) 5.5

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-TGF-α

Application Anti-Wrinkle·Skin Lifting·Skin Firming

sh-TGF-αTertiary Structure of NEX-TGF-α

Features

Synthetic Human Transforming Growth Factor alpha

·Reduces and prevents lines and wrinkles by actively generating new skin cells.·Enhances tone for skin that brimming with vitality & energy.·Nourishes skin that appears smoother, brighter & regains its youthful look.·Eliminates scars on face by forming new skin cells.

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Growth Factors/Others

Trade Name NEX-TGF-β

INCI Name rh-Polypeptide-22

CAS # 98726-64-8

Source Escherichia coli

Amino Acid 390

Molecular Weight (kDa) 44.3

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-TGF-β

Application Anti-Wrinkle·Skin Lifting·Skin Firming

sh-TGF-βTertiary Structure of NEX-TGF-β

Features

Synthetic Human Transforming Growth Factor beta

·Cures aging by inducing the proliferation, growth and differentiation of skin cells.·Refines texture glides (collagen) effectively and light up your skin.·Minimizes wound areas by inducing the formation of new skin cells.

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Trade Name NEX-SCF

INCI Name rh-Polypeptide-4

CAS # 133352-98-4

Source Escherichia coli

Amino Acid 188

Molecular Weight (kDa) 20.9

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-SCF

Application Anti-Aging·Anti-Wrinkle·Hair Growth

sh-SCFTertiary Structure of NEX-SCF

Features

Synthetic Human Stem Cell Factor

·Prevent wrinkle formation by creating new epidermal cells.·Hydrate dry skin and maintain optimal moisture level.

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Growth Factors/Others

Trade Name NEX-THY-b4

INCI Name rh-Oligopeptide-4

CAS # 77591-33-4

Source Escherichia coli

Amino Acid 44

Molecular Weight (kDa) 5.05

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-THY-b4

Application Anti-Wrinkle·Skin Lifting·Hair Growth

sh-THY-b4Tertiary Structure of NEX-THY-b4

Features

Synthetic Human Thymosin Beta-4

·Helps strengthen hair.·Stimulating hair follicles to produce healthier hair.·Support encourages hair growth by activation of hair follicle stem cells.·Stimulates collagen deposition in the wound.

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Trade Name NEX-PRX1

INCI Name rh-Polypeptide-79

CAS # 75227-39-3

Source Escherichia coli

Amino Acid 199

Molecular Weight (kDa) 22.1

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-PRX1

Application Anti-Oxidant·Skin Whitening

sh-PRX1

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-PRX1 concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-PRX1

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Synthetic Human Peroxiredoxin 1

·Anti-oxidant that reduces free radicals and inhibits the aged skin cells.·Provides a gorgeous up lifted complexion by reinforcing skin’s defenses.·Reduces and prevents lines and wrinkles by actively generating new skin cells.

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Growth Factors/Others

Trade Name NEX-PRX2

INCI Name rh-Polypeptide-80

CAS # None

Source Escherichia coli

Amino Acid 198

Molecular Weight (kDa) 21.9

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-PRX2

Application Anti-Oxidant·Skin Whitening

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-PRX2 concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Effect on Proliferation of HDFaControl 0.02 ppm 0.2 ppm

sh-PRX2Tertiary Structure of NEX-PRX2

Features

Synthetic Human Peroxiredoxin 2

·Anti-oxidant that reduces free radicals and inhibits the aged skin cells.·Provides a gorgeous up lifted complexion by reinforcing skin’s defenses.·Reduces and prevents lines and wrinkles by actively generating new skin cells.

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Trade Name NEX-SOD

INCI Name rh-Polypepptide-60

CAS # 9054-89-1

Source Escherichia coli

Amino Acid 178

Molecular Weight (kDa) 18.5

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-SOD

Application Anti-Oxidant·Anti-Aging

sh-SOD

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-SOD concen-tration of 0, 0.02, 0.2 ppm in HDFa cell.

Tertiary Structure of NEX-SOD

Effect on Proliferation of HDFa

Features

Control 0.02 ppm 0.2 ppm

Synthetic Human Superoxide Dismutase

·A free radical scavenger, balances out the number of excess radicals.·Protect skin from free radical skin damage.·Soothes the skin.

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Growth Factors/Others

Trade Name NEX-TRX

INCI Name rh-Polypeptide-2

CAS # 52500-60-4

Source Escherichia coli

Amino Acid 105

Molecular Weight (kDa) 11.7

pH 7.2 ± 0.2

Appearance Odorless solution

Endotoxin Level Less than 0.1 ng/ug of NEX-TRX

Application Anti-Oxidant·Skin Whitening

The HDFa cell proliferation stained with crystal violet and imaged with a 40X object-ive after treatment with NEX-TRX concentra-tion of 0, 0.02, 0.2 ppm in HDFa cell.

Effect on Proliferation of HDFaControl 0.02 ppm 0.2 ppm

sh-TRXTertiary Structure of NEX-TRX

Features

Synthetic Human Thioredoxin

·Anti-oxidant that reduces free radicals and inhibits the aged skin cells.·Provides a gorgeous up lifted complexion by reinforcing skin’s defenses.·Reduces and prevents lines and wrinkles by actively generating new skin cells.

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Antigens for Diagnostics

·NG-HIV-124·NG-HIV-141·NG-HIV-1120·NG-HIV-236·NG-PV-CSP·NG-TB-16

·NG-TB-35·NG-TB-85·NG-SY-15·NG-SY-17·NG-SY-47·NG-PV-MSP

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Antigens for Diagnostics

HIV-1 p24 Ag Recombinant

Catalog No. NG-HIV-124

Quantity As requested

Full Name HIV-1 p24 Ag Recombinant

Description Human Immunodeficiency Virus Type 1 (HIV-1) Antigen, p24, Recombinant contains the most immunoreactive region of HIV-1 p24. Immunoreactive with HIV-1 positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-HIV-124 should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

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Catalog No. NG-HIV-141

Quantity As requested

Full Name HIV-1 gp41 Ag Recombinant

Description Human Immunodeficiency Virus Type 1 (HIV-1) Antigen, gp41, Recombinant contains the most immunoreactive region of HIV-1 gp41. Immunoreactive with HIV-1 positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-HIV-141 should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

HIV-1 gp41 Ag Recombinant

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Antigens for Diagnostics

Catalog No. NG-HIV-1120

Quantity As requested

Full Name HIV-1 gp120 Ag Recombinant

Description Human Immunodeficiency Virus Type 1 (HIV-1) Antigen, gp120, Recombinant contains the most immunoreactive region of HIV-1 gp120. Immunoreactive with HIV-1 positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-HIV-1120 should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

HIV-1 gp120 Ag Recombinant

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

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Catalog No. NG-HIV-236

Quantity As requested

Full Name HIV-2 gp36 Ag Recombinant

Description Human Immunodeficiency Virus Type 2 (HIV-2) Antigen, gp36, Recombinant contains the most immunoreactive region of HIV-2 gp36. Immunoreactive with HIV-2 positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-HIV-236 should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

HIV-2 gp36 Ag Recombinant

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Antigens for Diagnostics

Catalog No. NG-PV-CSP

Quantity As requested

Full Name Pv CSP Ag Recombinant

Description Plasmodium vivax Antigen, CSP, Recombinant contains the most immunoreactive region of Pv CSP. Immunoreactive with Pv positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-PV-CSP should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

Pv CSP Ag Recombinant

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

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Catalog No. NG-TB-16

Quantity As requested

Full Name TB 16 kDa Ag Recombinant

Description Mycobacterium tuberculosis Antigen, 16 kDa, Recombinant contains the most immunoreactive region of TB 16 kDa.Immunoreactive with TB positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-TB-16 should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

TB 16 kDa Ag Recombinant

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Antigens for Diagnostics

Catalog No. NG-TB-35

Quantity As requested

Full Name TB 35 kDa Ag Recombinant

Description Mycobacterium tuberculosis Antigen, 35 kDa, Recombinant contains the most immunoreactive region of TB 35 kDa.Immunoreactive with TB positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-TB-35 should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

TB 35kDa Ag Recombinant

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

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Catalog No. NG-TB-85

Quantity As requested

Full Name TB 85 kDa Ag Recombinant

Description Mycobacterium tuberculosis Antigen, 85 kDa, Recombinant contains the most immunoreactive region of TB 85 kDa.Immunoreactive with TB positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-TB-85 should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

TB 85 kDa Ag Recombinant

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Antigens for Diagnostics

Catalog No. NG-SY-15

Quantity As requested

Full Name Syphilis 15 kDa Ag Recombinant

Description Syphilis Antigen, 15 kDa, Recombinant contains the most immunoreactive region of Syphilis 15 kDa. Immunoreactive with Syphilis positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-SY-15 should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

Syphilis 15 kDa Ag Recombinant

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

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Catalog No. NG-SY-17

Quantity As requested

Full Name Syphilis 17kDa Ag Recombinant

Description Syphilis Antigen, 17 kDa, Recombinant contains the most immunoreactive region of Syphilis 17 kDa. Immunoreactive with Syphilis positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-SY-17 should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

Syphilis 17 kDa Ag Recombinant

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Antigens for Diagnostics

Catalog No. NG-SY-47

Quantity As requested

Full Name Syphilis 47 kDa Ag Recombinant

Description Syphilis Antigen, 47 kDa, Recombinant contains the most immunoreactive region of Syphilis 47 kDa. Immunoreactive with Syphilis positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-SY-47 should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

Syphilis 47 kDa Ag Recombinant

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

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81

Catalog No. NG-PV-MSP

Quantity As requested

Full Name Pv MSP Ag Recombinant

Description Plasmodium vivax Antigen, MSP, Recombinant contains the most immunoreactive region of Pv MSP. Immunoreactive with Pv positive sera.

Source Escherichia coli

Reconstitution Renaturated purified antigen in Phosphate buffered saline (pH7.2) with 0.1% NaN3 as preser-vative.

Applications Suitable for use in ELISA and Western blots as a conjugate. Other applications have not been tested but use in such assays should not necessarily be excluded.

Storage NG-PV-MSP should be stored at -80℃ for long-term and -20℃ less than one month. Please prevent freeze-thaw cycles; Avoid multiple freeze-thaw cycles.

Concentration As available.

Purity > 95% pure as estimated by analysis of Coomassie blue stained SDS-PAGE.

※FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

Pv MSP Ag Recombinant

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Company History

2016. 05 Awarded 2016 No.1 Best patent of Korea “Mass production of r-Spider Toxin Protein by genetic engineering technology” (Hankook Ilbo)2015. 11 Relocating the headquarters of NEXGEN (2F, Building B1, 135, Gasan digital 2-ro, Geumcheon-gu, Seoul, S/Korea)2014. 12 Awarded 2014 No.1 ‘New technology of the Korean Beauty Industry’ (Hankook Ilbo)2014. 09 Identified QMS(Quality Management System : KS Q ISO 9001 : 2009 / ISO 9001 : 2008) by SBC certification institution2008. 11 Relocating the headquarters of NEXGEN to Seoul (371-57, Gasan-dong, Geumcheon-gu, Seoul)2005. 12 Awarded Korea’s 10 Best Technologies of 2005 (Plant-Made Human Protein Pharmaceutical)2001. 12 Awarded “Hiring Disable People” by Daejeon Metropolita city2000. 11 Awarded Employment Promotion Convention by Ministry of Labor 09 Designated as KMP (Korea New Millennium Products) with GM Detection 06 Designated as industrial R&D center (Korea Industrial Technology Association, No. 2000-1808) 04 Approved as Venture Enterprise by Ministry of Small and Medium Business Administration (No. 2000152271-0542)1999. 11 Incorporation

NEXGEN Biotechnologies, Inc.

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NEXGEN Biotechnologies, Inc. I Address: 2F, Building B1, 135, Gasan digital 2-ro, Geumcheon-gu, Seoul, S/KoreaTel: +82 2 857 1671 I E-mail: [email protected]