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- 1 - PROGRAM NEWS UPCOMING UTNP DISTINGUISHED LECTURES Please check www.neuroscience.utoronto.ca for updates. 'Stress, Glucocorticoids and the Hippocampus: A Lifespan Perspectives' SONIA LUPIEN University of Montreal Date: January 14 2009 2pm Location: Rm 3153, Med Sci Building, UofT Host: Evelyn Lambe JAY GIEDD Chief, Unit on Brain Imaging in the Child Psychiatry Branch National Institute of Mental Health Date: March, 2010 Time and day TBD Title: TBD Location: TBD Host: Hazel McBride DAVID BROOKS Professor, MRC Clinical Sciences Centre, Imperial College London Co-Chair, Experimental and Clinical Neuroscience Section Head, Neurology Group Title: TBA Date: Wednesday April 14, 2010 1pm Location: Rm 3153, Med Sci Building, UofT Host: Antonio Strafella CPIN students need to attend 75% of the UTNP Distinguished Lectureship Series each year NEW CPIN STUDENTS We would like to welcome the following students to the Collaborative Program in Neuroscience: Student Name Deg. Supervisor Department Sepehr Ehsani PhD Gerold Schmitt-Ulms LMP Salima Jiwani PhD Karen Gordon IMS UTNP on facebook The University of Toronto Neuroscience Program now has a facebook page: http://www.facebook.com/pages/University-of-Toronto- Neuroscience-Program/212564644049 Become a fan and check out the photos from the UTNP reception at SfN09! NOTICE TO GRADUATING STUDENTS Please notify the CPIN office upon your graduation to ensure that you will receive the notation "completed Collaborative Program in Neuroscience" on your degree transcript as well as a separate certificate suitable for framing from the CPIN office to indicate that you have completed the program's requirements. Please let the office know the address you wish your certificate sent to and please also send us your Thesis Title. If you have transferred from a Master’s degree to a PhD, please notify the CPIN office. www.neuroscience.utoronto.ca University of Toronto Neuroscience Program NEUROSCIENCE NEWSLETTER Volume 26 Number 5 January 2010 Director, UTNP: Michael G. Fehlings MD, PhD Assoc. Dir. UTNP; Director, CPIN: David R. Hampson, PhD Planning & Operations: Alexander A. Velumian, PhD, DSc Program Coordinator: Frazer Howard UTNP Administrative Office: Toronto Western Hospital, Rm. MP 11-315 Collaborative Program in Neuroscience Office: Rm 904, Leslie Dan Faculty of Pharmacy, Toronto ON M5S 3M2 Email:[email protected] | Telephone: 416-978 8761 Fax: 416-978-8511 | Website: www.neuroscience.utoronto.ca

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PROGRAM NEWS

UPCOMING UTNP DISTINGUISHED LECTURES

Please check www.neuroscience.utoronto.ca for updates.

'Stress, Glucocorticoids and the Hippocampus: A Lifespan Perspectives' SONIA LUPIEN University of Montreal Date: January 14 2009 2pm Location: Rm 3153, Med Sci Building, UofT Host: Evelyn Lambe

JAY GIEDD Chief, Unit on Brain Imaging in the Child Psychiatry Branch National Institute of Mental Health Date: March, 2010 Time and day TBD Title: TBD Location: TBD Host: Hazel McBride

DAVID BROOKS Professor, MRC Clinical Sciences Centre, Imperial College London Co-Chair, Experimental and Clinical Neuroscience Section Head, Neurology Group Title: TBA Date: Wednesday April 14, 2010 1pm Location: Rm 3153, Med Sci Building, UofT Host: Antonio Strafella

CPIN students need to attend 75% of the UTNP Distinguished Lectureship Series each year

NEW CPIN STUDENTS

We would like to welcome the following students to the Collaborative Program in Neuroscience:

Student Name Deg. Supervisor Department Sepehr Ehsani PhD Gerold Schmitt-Ulms LMP Salima Jiwani PhD Karen Gordon IMS

UTNP on facebook

The University of Toronto Neuroscience Program now has a facebook page:

http://www.facebook.com/pages/University-of-Toronto-Neuroscience-Program/212564644049

Become a fan and check out the photos from the UTNP reception at SfN09!

NOTICE TO GRADUATING STUDENTS Please notify the CPIN office upon your graduation to ensure that you will receive the notation "completed Collaborative Program in Neuroscience" on your degree transcript as well as a separate certificate suitable for framing from the CPIN office to indicate that you have completed the program's requirements. Please let the office know the address you wish your certificate sent to and please also send us your Thesis Title. If you have transferred from a Master’s degree to a PhD, please notify the CPIN office.

www.neuroscience.utoronto.ca University of Toronto Neuroscience Program

NEUROSCIENCE NEWSLETTER

Volume 26 Number 5 January 2010

Director, UTNP: Michael G. Fehlings MD, PhD Assoc. Dir. UTNP; Director, CPIN: David R. Hampson, PhD Planning & Operations: Alexander A. Velumian, PhD, DSc Program Coordinator: Frazer Howard

UTNP Administrative Office: Toronto Western Hospital, Rm. MP 11-315

Collaborative Program in Neuroscience Office: Rm 904, Leslie Dan Faculty of Pharmacy, Toronto ON M5S 3M2

Email:[email protected] | Telephone: 416-978 8761 Fax: 416-978-8511 | Website: www.neuroscience.utoronto.ca

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U OF T NEUROSCIENCE EVENTS AND SEMINARS

KREMBIL NEUROSCIENCE CENTRE GRAND ROUNDS Held Thursdays 7:30-8:30am Main Auditorium, 2 West Wing, Room 401 Toronto Western Hospital

ROTMAN ROUNDS Held Mondays 3:30pm Classroom 842, 8th Floor, Brain Health Complex, Rotman Research Institute

University Of Toronto, Department Of Psychology EBBINGHAUS EMPIRE MEETINGS Held Wednesdays 12:15 – 1:30 Room 3130 (third floor) Sidney Smith Bldg., St. George Campus, 100 St. George St.

"Control of breathing in hypothermia and hibernation; lessons from the cold" Dr. William Milsom Head of Zoology at the University of British Columbia Friday, January 8th from 2-3pm Ramsay Wright Rm 432 If you would like to meet with the speaker please contact Aqsa Malik at [email protected]

UNIVERSITY OF TORONTO 2009-2010 BRAIN AND BEHAVIOUR SEMINAR SERIES Talks begin at 4:00 pm sharp Location: Sidney Smith, Room # 2105

“Rewards, Opiates and Addictions: Changing Cholinergic and Dopaminergic Contributions” John Yeomans, PhD Psychology – St. George January 15 2010

“Sex and the Social Brain” Melissa Holmes, PhD Psychology – Mississauga February 12, 2010

“Making and Erasing Fear Memories” Sheena Josselyn, PhD Physiology, Hospital for Sick Children March 12, 2010

“Two Faces of Hippocampal Neurogenesis and their Functional Consequences” Martin Wojtowicz, PhD Physiology, BRAIN Research Platform April 9, 2010

Samuel Lunenfeld Research Institute of Mount Sinai Hospital “Analysis of Cytoskeletal Signaling Complexes that Regulate Synapse Formation” Dr. Scott Soderling Duke University, Department of Cell Biology Date: Wednesday, January 20, 2010 12pm Location: Mount Sinai Hospital, 60 Murray St. Level 3 Conference Rooms L3-201-202-203 (located on the 3rd floor of 60 Murray St. just before the double doors leading into the Cooper Center) Hosts: Dr. Anne-Claude Gingras (416) 586 – 5027 and Dr. Tony Pawson (416) 586 – 8262

March 22-26, 2010 - Toronto, Canada Organized by Donald T. Stuss, PhD and Robert T. Knight, MD Special Note - we are offering free on-site child care services for conference attendees, please understand that space is limited. http://www.rotman-baycrest.on.ca/index.php?section=5

UPCOMING NEUROSCIENCE MEETINGS

“NETWORKS: A FRAMEWORK FOR CROSS-DISCIPLINARY APPLICATIONS" The Institute for Biocomputation and Physics of Complex Systems (BIFI) of the University of Zaragoza, Spain, is organizing the Conference "Networks: A Framework for cross-disciplinary applications" that will take place from February 3 to February 6, 2010. More information can be found at http://bifi.unizar.es/events/bifi2010/ Complex Networks have been the subject of intense research during the last decade. After the burst of activity in this field, it has been increasingly recognized that network theory has become an essential ingredient for understanding and modeling the structure and dynamics of complex systems. The application of complex networks concepts and tools has rapidly spread across disciplines as diverse as Epidemiology, Sociology, Neuroscience and Computer Science. The common methodological framework provided by network theory is thus a crossroads in which different scientific perspectives share efforts and gain knowledge to their own applications. The aim of BIFI2010 is to bring together scientists studying complex systems in Physics, Sociology, Computer Science, Neuroscience and Biology that strongly rely on the use of complex networks for their research. The topics to be covered include, but is not limited to, the following scientific problems: - Predictive power of Network Theory. - Complex Networks in Technology, including communication and wireless networks. - Structure and Dynamics of Biological Networked Systems at all organizational levels (from the genome to ecosystems). - Social Networks.

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- Evolutionary Game and Graphs Dynamics. - Algorithms in and for Complex Networks. - Synchronization in Complex Networks, including Brain and neural networks. - Epidemic Spreading in Heterogeneous Populations.

"PATHWAYS TO RECOVERY: NEW GENERATION, NEW BREAKTHROUGHS, NEW HOPE" 2nd Annual Young Researchers' Conference Friday March 26, 2010 Royal Ottawa Mental Health Centre, Ottawa, ON This conference is aimed at individuals working in the fields of neuroscience, psychology, psychiatry, neurology, and mental health, ingeneral. Call for Presentation Abstracts Abstract Deadline: February 12, 2010 Registration Deadline: March 19, 2010 Featured speakers: Dr. Alain Brunet Researcher, Douglas Institute, Associate Professor, Department of Psychiatry, McGill University

Dr. Steffany A.L. Bennett Associate Professor, Department of Biochemistry, Microbiology, & Immunology, University of Ottawa

Dr. John D Stead Associate Professor, Department of Psychology, Carleton University

For further information and registration, please visit: http://www.imhr.ca/research/youngresearch/conference-e.cfm For any questions please contact: [email protected]

XXXIIND INTERNATIONAL SYMPOSIUM OF THE GRSNC “Enhancing performance for perception and action - Multisensory integration, neuroplasticity & neuroprosthetics” May 10-11, 2010 Université de Montréal The XXXIInd International Symposium of the Groupe de recherche sur le système nerveux central, entitled "Enhancing performance for perception and action – Multisensory integration, neuroplasticity & neuroprosthetics", will be held on May 10-11, 2010 at the Université de Montréal. The preliminary program is now available at: http://www.grsnc.umontreal.ca/32s/prog-prel.html Registration will open on November 17th, 2009. The symposium will be held at the Université de Montréal and is organized by Drs Elaine Chapman, Andrea Green, John Kalaska, and Franco Lepore. The objective is to provide an overview of the various neural mechanisms that contribute to learning new motor and sensory skills, and to adapting to changed circumstances including the use of devices and implants to substitute for lost sensory or motor abilities (brain machine interfaces, BMI). The symposium will focus on recent developments covering four major themes: 1) Mechanisms to enhance motor performance;

2) Mechanisms to enhance sensory performance; 3) Multisensory interactions and its role in enhancing action and perception; 4) Technological interventions to restore action and perception (BMI). Submissions are invited for a limited number of poster presentations. Deadline for poster submissions: March 31st, 2010.

May 15-18 2010 Ottawa, Ontario Westin Hotel www.can-acn2010.org

THE 10TH INTERNATIONAL CONFERENCE ON ALZHEIMER’S & PARKINSON’S DISEASES Barcelona, Spain, March 9-13, 2011 2346 professionals from Western and Eastern Europe, the Far East, Middle East, North and South America, and Australia attended AD/PD 2009 in Prague ─ the fastest growing Conference on Alzheimer’s (AD) and Parkinson’s diseases (PD) a premier, landmark biennial conference. www.ad-pd.org

FUNDING ANNOUNCEMENTS

SSHRC MAJOR COLLABORATIVE RESEARCH INITIATIVE PROGRAM SSHRC will be running the next Major Collaborative Research Initiative (MCRI) competition, with letters of intent due at SSHRC on January 31, 2010. The MCRI is SSHRC's largest funding opportunity, aimed at enabling multidisciplinary teams to probe critical questions that demand a multi-lens perspective in the social sciences and humanities. Successful proposals can receive up to $2.5 million over 7 years. The MCRI is also a highly competitive program. To assist those faculty members wishing to lead an MCRI proposal, Research Services has planned, and will offer, strategic support that includes:

• coordination of internal peer review to assist applicants at the Letter of Intent Stage, and to those who are invited to prepare a Full Proposal.

• advice and assistance, in partnership with Divisions, on the mechanics of the proposal, including how to

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identify commitments from other sources, and partners to the proposal.

Program information is available on our website at: http://www.research.utoronto.ca/for-researchers-administrators/funding-sources/funding-opps/?showopp=451

National Alliance for Research on Schizophrenia and Depression (NARSAD) : Independent Investigator Award. NARSAD's) Independent Investigator Award provides support for investigators during the critical period between the initiation of research and the receipt of sustained funding. Basic or clinical investigators are supported, but research must be relevant to schizophrenia, major affective disorders, or other serious mental illnesses. The program is intended to facilitate innovative research opportunities. Deadline for Submissions: March 1, 2010.

FOX FOUNDATION FOR PARKINSON'S RESEARCH, MICHAEL J. (MJFF) : Rapid Response Innovation Awards - Edmond J. Safra Core Program for PD Research. To promote testing of novel hypotheses, funding from our Rapid Response Innovation Awards program quickly supports high-risk, high-reward projects with little to no existing preliminary data, but potential to significantly impact our understanding or treatment of PD. Deadline for Applications: Continuous.

POSITIONS AVAILABLE

UNIVERSITY OF TORONTO & AFFILIATED INSTITUTIONS

CIHR PRE- AND POST DOCTORAL FELLOWSHIP OPPORTUNITIES We are pleased to announce the availability of Canadian Institutes of Health Research-funded graduate student and Post Doctoral Fellowships for our “CIHR Strategic Training Grant in the Development of Biological Therapeutics”. This multi-division University of Toronto program has 14 Principal Mentors and been awarded $1,800,000 over the next 5 years. In the context of this program, “biological therapeutics” is defined as encompassing nucleic acids such as small interfering RNAs (siRNA), peptides and proteins including antibodies, and viruses and viral vectors. Projects will span the gamut from basic to applied research. Depending on the research project, Postdoctoral Fellows and graduate students will receive training in bioinformatics, formulation and delivery of nucleic acids and proteins, and the analysis of the metabolism and fate of these macromolecules in vivo. Areas of application include neuroscience, cancer, and

immunology. Each trainee will have a primary mentor and secondary mentor with whom they spend a minimum of 1 month per year. Our collaborative environment will deepen knowledge and technical skills, promote team oriented research with colleagues, and increase exposure to cross-disciplinary research in the fields of neuroscience, ophthalmology, cancer, immunology, and drug delivery. Finally, through an industrial internship program, this program will also provide opportunities to work (short-term) with the private sector (pharmaceutical and biotechnology companies) to acquire additional technical skills. Please see our Website: http://www.utoronto.ca/biotherapeutics_training/ Please email a CV and a1 page cover letter outlining your suitability and specific interest in working with one of the 14 mentors to: [email protected]

CELL AND SYSTEMS BIOLOGY – UNIVERSITY OF TORONTO The Department of Cell & Systems Biology at the University of Toronto

invites applications for a tenure track faculty position to be appointed at the level of Assistant or Associate Professor beginning July 1, 2010. We are interested in outstanding candidates that complement existing strengths in the department in the areas of genomics, cell and developmental biology, and neurophysiology using high-throughput approaches or gene/protein network analyses with genomic, proteomic, or advanced cell biological and imaging tools. We particularly encourage applications from candidates who are addressing fundamental questions in plant and microbial biology but will consider all outstanding candidates within the framework of our department. For more information about the Department of Cell & Systems Biology, please visit our home page at http://www.csb.utoronto.ca/ Candidates should have at least two years of research experience beyond their doctoral degree. In addition to pursuing a vigorous, internationally-recognized research program, the successful candidate will demonstrate potential for excellence in undergraduate and graduate teaching in the molecular life sciences. The successful candidate would also be expected to network with researchers across the university to take advantage of the extensive resources in cell and systems biology at the University of Toronto and its affiliated institutions. Salary will be commensurate with qualifications and experience. Qualified candidates are encouraged to submit their applications online at: www.jobs.utoronto.ca/faculty.htm. Applicants should submit a single pdf file (<2Mb) that includes a cover letter, their curriculum vitae, and statements of research and teaching interests. Applicants should also arrange for at least three confidential letters of recommendation to be sent directly to: Professor Ulrich Tepass, Chair, Department of Cell & Systems Biology, University of Toronto, 25 Harbord Street, Toronto, Ontario M5S 3G5, Canada; or by email to [email protected] by January 15, 2010.

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TA POSITIONS FOR GRADUATE STUDENTS, HUMAN BIOLOGY PROGRAM The Human Biology Program is offering a number of TA positions for Graduate students interested in including teaching as a part of their academic education. TA positions are available in a number of our undergraduate courses. The positions vary and range from 35 hours to 65 hours and the rate of payment is in accordance with the new CUPE 3902 Unit 1 collective agreement. Please see the links below for job position postings information and application form. Please post the job positions on any Graduate bulletin board and/or as an email to your graduate students. If you have any questions please feel free to contact Ron Wilson, Associate Director Human Biology Programs by phone at 416-946-7609 or by e-mail at [email protected]. http://hmb.utoronto.ca/index.php?q=node/168

UNITED STATES

POSTDOCTORAL POSITION, UNIVERSITY OF MICHIGAN A Postdoctoral position in the Molecular & Behavioral Neuroscience Institute and the Department of Neurology the at the University of Michigan is open immediately as part of a 5 year NINDS funded research program to study how aberrant migration of granule cells in the dentate gyrus region of the hippocampus contributes to mesial temporal lobe epilepsy (mTLE). The project entails using a multidisciplinary approach that combines aspects of molecular genetics (transgenic mice and/or transgene delivery using viral vectors) and electrophysiology. Successful applicants must have a recent Ph.D. or M.D. degree and will have had extensive training in electrophysiology (preferably using an in vitro slice preparation) and some familiarity with molecular approaches and/or a background in epilepsy research . Experience with rodent EEG recording considered a plus. Please send (V, brief description of research interests and complete contact information for three references to Dr. Geoffrey G. Murphy ([email protected]). The Molecular & Behavioral Neuroscience Institute 205 Zina Pitcher Place Ann Arbor, MI 48109-0720 734.763.4235 734.647.4130 fax

POSTDOCTORAL POSITIONS, UNIVERSITY OF ROCHESTER Two DoD-funded postdoctoral positions are available immediately. Our laboratory uses state of the art optical techniques to gain insights into the mechanisms controlling brain plasticity during normal development and disease. We are currently looking for highly motivated scientists to join our team and pursue two projects: 1. Explore the use of optogenetic tools to affect the progression of seizure activity in in vitro and in vivo rodent models; 2. Investigate the effects of neuro-active drugs on the growth and metastasis of brain tumors. The University of Rochester provides an excellent research environment with a

large neuroscience faculty and excellent basic and clinical research programs. Rochester is located on the southern shore of Lake Ontario in upstate New York within driving distance of New York City, Toronto and Buffalo and boasts a vibrant arts and cultural life. The Rochester region has been highly ranked for its quality of life and family-friendliness in many different venues. Successful candidates will have a PhD or MD and experience in animal surgery and fluorescence microscopy, as well as demonstrated record of productivity. Candidates interested in the optogenetic project must also have experience in electrophysiology. Salary will follow NIH guidelines. We are especially interested in those candidates who are motivated to develop their independent careers as investigators.

Applicants should send their curriculum vitae, list of publications and references, and a letter describing their interests to Ania Majewska ([email protected]).

INTERNATIONAL

SCIENTIFIC EXCELLENCE AND ACADEMIC TRADITION: EARN YOUR PHD IN GOETTINGEN, GERMANY! Open Positions for BSc and MSc Graduates in Göttingen: Join one of our international Master-/PhD programs of the Göttingen GraduateS chool for Neurosciences and Molecular Biosciences/GGNB! BACHELOR STUDENTS who will have graduated by fall 2010 in the life sciences and related natural sciences apply here: International MSc/PhD Program / Max Planck Research School “Neurosciences”:<http://www.gpneuro.uni-goettingen.de> www.gpneuro.uni-goettingen.de MASTER STUDENTS with a background in the neurosciences, molecular life sciences, biophysics or related natural sciences apply here: Graduate School GGNB:

Find detailed information about graduate education and research opportunities offered by our international programs on the websites of our programs.

<http://www.ggnb.uni-goettingen.de>www.ggnb.uni-goettingen.de

APPLICATION DEADLINE: 15 January 2010 We are looking forward to your application! Best wishes from Göttingen, Michael Hörner -- Prof. Dr. Michael Hörner Georg August University Göttingen Coordinator MSc/PhD Neuroscience Program International Max Planck Research School European Neuroscience Institute ENI Grisebachstraße 537077 Göttingen, Germany phone: 49-551-39-12307 /-91244 fax : 49-551-39-12308 email: [email protected] http://www.gpneuro.uni-goettingen.de

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SUBMISSION & CONTACT INFORMATION Email: [email protected] Fax: 416-978-8511 Attn: Frazer Howard Submissions to the newsletter must be made by the 25th of the preceding month. Previous issues of the newsletter are posted on our website at: http://www.neuroscience.utoronto.ca/newsletter If you no longer would like to receive this newsletter, please contact [email protected] with subject line “unsubscribe from UTNP Newsletter”

UTNP DISTINGUISHED LECTURESHIP SERIES SELECTION COMMITTEE MEMBERS

D.R. Hampson / PHARM. SCI. (Chair) M.G. Fehlings / INST. MED. SCIENCE (ex-officio) E. Lambe / PHYSIOLOGY M. Aarts / CELL & SYSTEMS BIO. D. Broussard / PHYSIOLOGY

J. Peever / CELL & SYSTEMS BIOLOGY P. Fletcher / PSYCHOLOGY Gerold Schmitt-Ulms / LAB. MED. PATHOBIOL Taufik Valiante / INST. MED. SCIENCE B. Stefanovic / MEDICAL BIOPHYSICS

COLLABORATIVE GRADUATE PROGRAM IN NEUROSCIENCE COMMITTEE MEMBERS

D.R. Hampson / PHARM. SCI. (Dir) J.O. Dostrovsky / PHYSIOLOGY (Advisor) W.M. Burnham / PHARMACOLOGY P. Carlen / INST. MED. SCIENCE L.F. De Nil / SPEECH LANG. PATHOL. Z. Jia / PHYSIOLOGY M. Lewis / HDAP S. Nag / LAB. MED. PATHOBIOL.

J. Peever / CELL AND SYSTEMS BIOLOGY J. Roder / MOL. GENETICS B.J. Sessle / DENTISTRY M. Shoichet / INST. BIOMAT. & BIOMED. ENG. B. Stefanovic / MEDICAL BIOPHYSICS W. Trimble / BIOCHEMISTRY J.W. Wells / PHARMACY J.S. Yeomans / PSYCHOLOGY K. Zabjek / REHAB. SCI.