Resume last Update November 2018 1

Education:

MD, PhD pharmacology-Faculty of Medicine-Alexandria University

MBBCH, Alexandria Faculty of Medicine 1984

Master Degree in Pharmacology 1991-Alexandria Faculty of Medicine

Doctor Degree in Pharmacology 1996- Alexandria Faculty of Medicine

Diploma in microbiology 1998,High Institute of health Alexandria University

Languages:English/ French

1. Working Experience: Faculty of Medicine - Alfateh University , Tripoli,

Libya

Participation in teaching, training and exams of clinical pharmacology courses

To undergraduates and junior staff (2000-2005)

2. Faculty of Medicine - Alexandria University (first, second, third and fourth

years).

i. Participating in practical , applied lessons, lectures

ii. Participate in the teaching of team based learning

iii. Participation in teaching and training in clinical pharmacology courses and all

exams

Prof. Inas ElSayed Darwish Hassan Ghoneim Address: 226 Port Said Street- Sporting , Abu Elhol Tower A- flat

4Apartment 10Alexandria

Phone no.: 03 52 33 601 - Office 180 - cellular +20 1099997626

E-mail: inas.darwish@pua.edu.eg.

Military status : exempted

Date of birth: 29/01/1961 Nationality: Egyptian

Status: Married Driving License: Valid

Resume last Update November 2018 2

3. Faculty of Medicine (Division of International Education) - Alexandria

University (first, second, third, fourth and fifth years).

Participation in teaching, training and exams in clinical pharmacology courses

4. Faculty of Dentistry - Alexandria University (second year) from 2006 to 2016

Faculty of Dentistry (International Education Division) - Alexandria

University (second year).

5. Assigned to the Faculty of Medicine - University of Kafr El Sheikh to teach

and establish curricula for the Faculty of Medicine, Dentistry and Physical

Therapy College as well as the curricula of new recruits in the Faculty of

Medicine (since 2016 -2018)

6. Participation in the teaching of pharmacology lectures for postgraduate

students in the MD and Ph.D. Pharmacology and clinical masters and

examinations in the Faculty of Medicine - Alexandria University since 2006

until now.

7. Teaching and exam Pharmacology for doctoral degree in neurosurgery,

Faculty of Medicine since 2007 -2018.

8. Teaching the Master of Nursing College in the field of critical nursing since

2006 until 2017

9. Participation in the preparation, development and teaching of the most recent

courses for postgraduate studies in the department, such as the

Pharmacoeconomic , medicinal plant therapeutics - clinical trials - PhD and

the development of courses for professional diplomas granted by the College

10. Professor / Pharmacology and therapeutic department/Faculty of Pharmacy/

Pharos University in Alexandria

Personal Skills:

I- Teaching and curricula implementation and evaluation 1. Participated in the preparation of books of pharmacology and practical

manuals and the tutorials in Pharmacology for the first and second years and

the third medical undergraduates to Alexandria and kafrelsheikh Universities.

2. Participation in the development of the book of pharmacology of the Faculty

of Dentistry second band

3. Developing the methodological content, coordinating, and issuing a book in

cooperation with the departments of pathology, community medicine,

biochemistry, medical heredity as well as the departments of dermatology and

oncology for the sixth unit for the first three consecutive years 2010-2012.

4. Development of the systematic content of pharmacology - Alexandria

University in the specialties of critical care nursing and emergency medicine

since 2006 and until 2016

5. Participation in the control of the sixth year cumulative and fourth year and

the internal control of pharmacology for the first, second and third years of

Resume last Update November 2018 3

human medicine - Alexandria University, as well as for the clinical and dental

examiners

6. Responsibility and participation in the control tasks of the second division of

the international program throughout the year in various stages

(Partial integrated system and system modules) since 2008-2012.

II- Laboratory and Clinical pharmacology 1. Pharmacokinetic study and its computer programedcalculations

2. Power lab experiments: smooth muscle preparations ( intestine, aortic,

trachea, colon and gastric)ex vivo studies

3. In vivo blood pressure, behavioral tests evaluations

4. Inductions of certain Experimental models as : ulcerative colitis,

epilepsy and Parkinson disease

5. Biochemical measures and assay with kits , ELIZA

Publications

1. A Study on the possible protective and curative effects of Ketotifen,Nigella Sativa

Oil ,Allopurinol with Dimethyl sulphoxide and Prednisolone on

Trinitrobenzinesulphonic acid induced colitis in rats.

P2D102: in Toxicology Letters supplement 1/95. Abstracts of the

International Congress Of toxicology-ICT VIII, Paris,5-9 July 1988."

Chemical Safety for the 21st Century"

2. Study of the effect of cigarette smoke exposure, medroxy progesterone acetate

injection on oxidative damage in female rats.

Alexandria Medical Journal Vol. 41 No. 2 April 1999.

3. Striking by metabolic modulation to protect against intestinal ischemic /

reperfusion injury in rats by different agents.

The 15th Annual conference for the Egyptian Society of Toxicology

Proceedings, Vol. I, 6-7 October, 1999 ,Alexandria University.

4. Can isradipine, quinapril, valsartan and pentoxifylline protect against mucosal

ischemic injury in rats ?

The 15th Annual conference for the Egyptian Society of Toxicology

Proceedings, Vol.II, 6-7 October,1999 ,Alexandria University.

5. Inhibition of tumor necrosis factor - and nitric oxide synthase has a

hepatoprotective effect in carbon-tetrachloride –induced liver injury in rats.

Egyptian Society of Pharmacology and Experimental therapeutics Vol. 20

No.2 July 2001.

6. Can ACE inhibitors or AT1 antagonists protect against an experimental model of

pulmonary fibrosis in rats?

Bulletin of Alexandria Faculty of Medicine Vol. 41 No. 4 October-

December 2005 .

7. “Role of Nigella Sativa oil , thymoquinone with and without pyrimethamine in

Freund‟s adjuvant arthritis in rats”

Bulletin of Alexandria Faculty of Medicine Vol. 42 No. 1 January 2006.

Resume last Update November 2018 4

8. Role of trace metals, selenium and zinc in pilocarpine –induced epilepsy in rats.

Bulletin of Alexandria Faculty of Medicine Vol. 42 No. 1 January 2006.

9. "Role of simvatatin ,tetrandrine and candesartan in experimental induced liver

fibrosis in Rats"

Bulletin of Alexandria Faculty of Medicine Vol. 42 No. 1 January 2006.

10. Effect of Salicylate and retinoic acid on heat shock protein 70(HSP70) and lipid

peroxides in Experimental testicular torsion /detorsion in rats.

Alexandria Medical Journal Vol. 41 No. 4 April 2007.

The International Pharmacy Conference "Recent advances in Pharmaceutical

research and technology"

11. Could vitamin K2 guard against experimentally induced gastric stress ulcers in

rats .Alexandria Medical Journal Vol. 41 No. 4 April 2007

The 16th World Congress of Basic and Clinical Pharmacology, which took

place 17 – 23 July 2010 in Copenhagen, Denmark.

12. Do desipramine [10,11-dihydro-5-[3-(methylamino) propyl]-

5hdibenz[b,f]azepinemonohydrochloride] and fluoxetine[n-methyl-3-phenyl-3-

[(trifluoromethyl)phenoxy]-propan-1-amine] ameliorate the extent of colonic

damage induced by Acetic Acid in Rats?

The Journal of Pharmacology and Experimental Therapeutics. December

2008; 327:602-609

13. Anti – inflammatory activity of JuniperusPhoenicea Part III

The 16th International Conference of the Lebanese Association for the

Advancement of Science proceedings as abstract in 14 November 2009.

14. The possible role of peroxisome proliferator-activated receptors agonists in the

vascular reactivity and myocardial changes induced by long-term blockade of

nitric oxide synthesis in the rat.

IN: The Annual Conference of Pan Arab Society of Interventional Cardiology

„Cardio Alex 2009” June 23-26 2009. Oral Presentation of the Paper; and

won the first prize in the abstract competition.

15. Biochemical modification of oxidative stress induced by monosodium glutamate

in rats with some antioxidants.

16. Menatetrenone and Nigella sativa: A prophylactic role in corticosteroid induced

osteoporosis in rats

The 16th World Congress of Basic and Clinical Pharmacology, which took

place 17 – 23 July 2010 in Copenhagen, Denmark.

17. Study of Possible Colonic Mucosal and Motility Changes in Experimental Acetic

Acid Induced Colitis in Male Albino Rats under the effect of Oral Barley

Administration in Comparison with Venlafaxine

Journal of Physiology Pharmacology Advances Dec 2012; 2(9): 319-329

Resume last Update November 2018 5

18. Behavioral and neuronal biochemical possible effects in Experimental induced

chronic mild stress in male albino rats under the effect of oral barley

administration in comparison venlafaxine

Int J PhysiolPathoPhysiolPharmacol 2013 June 5(2):128-136.

19. Design, Synthesis and Pharmacodynamic evaluation of some Novel Pyrimidines

as Calcium Channel Blockers

Frontiers in Medicinal Chemistry symposium At; San Francisco, CA from: 22-

26 June 2013

20. Is Curcumine effects comparable to5-aminosalicylic acid or budesonide on a rat

model of ulcerative colitis induced by trinitrobenzene sulfonic acid?

In: The conference proceedings: International conference of Pharmacology and

pharmaceutical Medicine - in Kuala Lumpur, Malaysia during August 22-23,

2013Paper ID Code: MY80000

21. β2-adrenoceptor agonists as potential therapeutic drugs in diabetic peripheral

neuropathy

European Journal of Pharmacology (2015) Volume (746) 89-95.

22. Does serum visfatin represent a biochemical marker to an experimental peripheral

neuropathic pain in mice?

Pharmacology (2015): DOI: 10.1159/000439537

23. Potential neuroprotective role of verapamil in experimentally induced chronic

sciatic nerve constriction in mice

British Journal of Medicine & Medical Research (2015) Vol.8 (9): 781-789.

24. A comparative study of the protective effects of interferon-α2b and spirulina

against carbon tetrachloride induced hepatic fibrosis in mice, role of chitinase-3-

like-1.Alexandria Medical Journal (2010 ) Vol . 52 (1) January: 68-73

25. Role of targeting asymmetric dimethylaRginine in stReptozotocin-induced

diabetic nephRopathy in Rats: effects of tauRine and Rosiglitazone

IE Darwish, CA Ismail, AA Guemei, A Abdelbary .2016.ACTA

ENDOCRINOLOGICA-BUCHAREST 11 (4), 449-456

26. Evaluation of the combined antitumor effect of Gold Nanoparticles/photodynamic

therapy and Cisplatin in Experimental Hepatocellular Carcinoma Cells. (

unpublished)

Research interests

1. Field of specialization: Neuro-gastrointestinal pharmacology and

Pharmacokinetics

2. Master thesis 1991

The effect of captopril on digoxin kinetics in heart failure patients.

3. Doctor Thesis 1996

Resume last Update November 2018 6

A study on the possible protective and curative effects of ketotifen, nigella

sativa oil, allopurinol with dimethylsulphoxide and prednisolone on

trinitrobenzinesulphonic acid induced colitis in rats.

4. Other post doctor degrees

Microbiology Diploma: high institute of Health, Alexandria University 1998

5. Supervised thesis

a. Doctor Degree

- A Study of the possible effects of 5-aminosalicylic acid, budesonide versus

curcumine, tetracycline, pravastatin, and enalaprilat on a rat model of

ulcerative colitis induced by trinitrobenzene sulfonic acid.2010

- A comparative study of the protective and curative effects of interferon-2b,

alfacalcidol and spirulina on carbon tetrachloride induced hepatic fibrosis in

mice 2014

- Antiepileptic drugs and cognitive impairment in a rat alzheimer‟s model

induced by intaventricular injection of colchicine. 2016

- High-throughput drug screening in induced pluripotent stem cell based

facioscapulohumeral muscle dystrophy disease model ( double channel USA

2018)- Not yet discussed

b. Master Degree:

- A comparative study of the protective effect of alendronate , simvastatin , oil

of nigella sativa and menatetrenone on methyl-prednisolone induced

osteoporosis in rats.2010

- The effect of escitalopram and magnesium on the depressive-like behaviour,

hippocampal serotonin turnover and plasma corticosterone level in post-status

epilepticus rats 2014

- Study of the effect of montelukast and celecoxib on renal ischemia reperfusion

injury in rats ( 2016)

- Proposed project to DTDF under title of : Bitter receptor modulation: insider

to management of neurodegenerative and inflammatory disorders.2017

Conferences, Symposia, Workshops: 1. Allergy Day 8th May 1998 . Alexandria

2. The Fifteenth Scientific Conference of the Egyptian Society of Toxicology,

held in Alexandria from 6-7 October 1999. A research paper entitled: Striking

by metabolic modulation to protect against intestinal ischemic / reperfusion

injury in rats by different agents.

3. The World Congress of the Egyptian Association of Drugs and Experimental

Therapy in association with the African, Asian and Arab Association of Drugs

held in Cairo from 3 to 6 December 1999.

Resume last Update November 2018 7

4. In the sixth scientific symposium of the Department of Pharmacology Faculty

of Medicine in partnership with the Faculty of Pharmacy - University of

Alexandria and the Faculty of Medicine, University of Cairo and Ain Shams,

held on 23/12/1997.

5. “Back to nature in fields of therapy.”- and participation speech entitled:

a. “The contribution of nature to current therapeutics.”

6. The sixth annual scientific conference of the basic medical union held in

Alexandria from 26 to 27 November 1998 under the title of the fight against

infection. Infection Control

7. African Conference for the Research of Medical Plants of Al-Fateh University

- College of Pharmacy from 21 to 23 October 2000 Tripoli - Libya under the

title:

i. African Conference on Medical Plant Research

8. The Twenty-fourth Conference of African Medicine of the Council of Medical

Professions in cooperation with FSG Communication LTD, UK, in the

framework of continuing medical education held in Libya from 25-27 May

2003 under the title: Seminar Presentation and International Exhibition

Program

9. The seventh annual scientific conference of the basic medical union held in

Alexandria from 28-29 October 1999 under the title: Recent advances in

diagnosis and treatment

10. The World Conference held in Alexandria from April 26 to 29, 2006 under the

title: Changing Lives/ Bio vision Alexandria 2006

11. Allergy Conference held in Alexandria on 11 May 2006 under the title:

TheAllergy DayEighth

12. The Fourth Scientific Conference of the Egyptian Association for the

Advancement of Basic Medical Sciences held in Alexandria on 13 February

2006 under the title: Physical Exercise in Health and disease

13. The 27th Annual Scientific Conference held at the Faculty of Medicine,

Alexandria, 23-24 March 2006 - titled "Medical research"

14. The 14th Annual Scientific Conference held at Alexandria Medical Syndicate

on 6-8 December 2006 "Recent advances in diagnosis and treatment"

15. And gave a speech entitled: "Newly emerged antibiotics"

16. Fifth scientific conference of the Egyptian Association for the Advancement

of Basic Medical Sciences held in Alexandria on 26 February 2007 under the

title: Breast cancer, hope and cure.

17. - Conference of the Faculty of Medicine VIII and XX held at the Faculty of

Medicine University of Alexandria on 5-6 April 2007 "Hospital and health

care management"

Resume last Update November 2018 8

18. - The twenty-first annual scientific conference and the second in the field of

laboratory medicine held at Alexandria Medical Syndicate on 2-4 May 2007

under the title: "Recent advances in laboratory Medicine"

19. - Thirty-sixth Conference of Allergy and Clinical Immunology held in

Alexandria from 9 to 10 August 2007 under the title: Asthma

postgraduate training program.

20. Allergy Conference held in Alexandria on May 1, 2008 under the titleThe

Tenth Allergy Day.

21. Conference of the Faculty of Medicine XXIX held at the Faculty of Medicine

- University of Alexandria on 14-16 May 2008 under the title: "Future

Medicine"

22. Conference of the Dental Research Center Alexandria II in cooperation with

the Ministry of Health - Faculty of Medicine University of Alexandria on 23-

25 April 2009 under the title: "Seeking Perfection"

23. Conference of the Faculty of Medicine held at the Faculty of Medicine -

University of Alexandria on 11-12 June 2009 under the title: Nanomedicine

from theory to therapy"

24. The sixth scientific conference of the Egyptian Association for the

Advancement of Basic Medical Sciences held in Alexandria on 30 March

2009 under the title: "Parasitic liver diseases"

25. Allergy Day,the Eleventh - Presenting a research at the Allergy Conference

held in Alexandria on 30 April 2009 under the title: "Integrated and

Interactive Allergy diagnosis and Therapy 2009."

a. And delivered a paper entitle

b. Pharmacological hints in asthma treatment"

26. Presentation in Lebanon on 14 November 2009 at a conference: The 16th

International Conference of the Lebanese Association for the a advancement

of Science :

i. Anti – inflammatory activity of JuniperusPhoenicea Part III

27. The Annual Conference of Allergy and Immune Immunology - 19 November

2009 under the title: Allergy and immunology by the Egyptian Society Of

Allergy and Immunology

28. The 150th Annual Conference of the Egyptian Society of Pharmacology and

Experimental Therapy held in Cairo on 15-16 March 2010 under the title:The

ESPET 51st Conference March 15-16, 2010

29. Two papers were presented in Lebanon on 6-7 May 2010 at a global

conference: The International Pharmacy Conference "Recent advances in

Pharmaceutical research and technology"

Resume last Update November 2018 9

30. The first was: Effect of Salicylate and retinoic acid on heat shock protein

70(HSP70) and lipid peroxides in Experimental testicular torsion /detorsion in

rats.

31. The second was: Biochemical Modifications of Oxidative Stress Induced by

Monosodium Glutamate In Rats with some anti-oxidants

32. Participation in two papers at the 16th World Congress of Basic and Clinical

Pharmacology held in Copenhagen, Denmark, July 17-23 The 16th World

Congress of Basic and Clinical Pharmacology, which took place 17 – 23 July

2010 in Copenhagen, Denmark.

33. First: Could vitamin K2 guard against experimentally induced gastric stress

ulcers in rats

34. Second: Menatetrone and nigella sativa: a prophylactic role in corticosteroid

induced osteoporosis in the rat

35. Conference held at the Faculty of Medicine - University of Alexandria on 29-

30 December 2010 under the title: International Conference on Nanomedicine

in Cancer

36. Conference held at the Faculty of Medicine - University of Alexandria on

April 1, 2010 under the title: The third annual healthcare quality and

accreditation symposium-Accreditation- passing over the challenges

37. Scientific Conference of the Egyptian Association for the Advancement of

Basic Medical Sciences held in Alexandria on 22 March 2010 under the title:

"Immunovascular disorders"

38. The 8th Scientific Conference of the Egyptian Association for the

Advancement of Basic Medical Sciences held at the Faculty of Medicine -

Alexandria University on 24 March 2011 under the title: "Diabetes from

theory to therapy"

39. The ninth scientific conference of the Egyptian Association for the

Advancement of Basic Medical Sciences held at the Faculty of Medicine -

Alexandria University on 22 April 2012 under the title: "The integrated

symposium; Hand in Hand to combat renal failure"

40. The 10th Scientific Conference of the Egyptian Association for the

Advancement of Basic Medical Sciences held at the Faculty of Medicine -

Alexandria University on 11 April 2013 under the title: "Medicine and The

search For the Fountain of Youth"

41. The annual conference of the Department of Pharmaceutical Chemistry held at

the Conferences Hall of the Faculty of Pharmacy, University of Alexandria on

May 4, 2013 under the title: Chemistry is life

42. World Congress of Medical Chemistry held in San Francisco, California, 22-

26 June 2013. Under title of :Frontiers in Medicinal Chemistry symposium At;

San Francisco, CA from: 22-26 June 2013

Resume last Update November 2018 10

43. Search as a poster under the title: Design, Synthesis and Pharmacodynamic

evaluation of some Novel Pyrimidines as Calcium Channel Blockers

44. World Congress of Pharmaceutics and Pharmaceutical Medicine held in Kuala

Lumpur and Malaysia; On 22-23 August 2013 , Poster Presentation entitled

45. Is Curcumine effects comparable to5-aminosalicylic acid or budesonide on a

rat model of ulcerative colitis induced by trinitrobenzene sulfonic acid?

46. The annual conference of Clinical Pharmacology department in collaboration

with biological lab, anatomy department , Faculty of kaferelsheikh March

2016 titled : Pharmacogenetics 1

47. The second annual conference of Clinical Pharmacology department in

collaboration with Cardiology and angiology department , Faculty of Medicine

April 2018 titled : New trends in cardiovascular Pharmacotherapy

48. Workshop held at the Faculty of Medicine - University of Alexandria on 14

May 2008 under the title: Accreditation and quality assurance training

49. Workshop held by the Faculty of Medicine - Alexandria University on 13

April 2008 under the title: Curriculum development and implementation "

50. Workshop held by the Faculty of Medicine - Alexandria University on 14

April 2008 under the title : Principles and practice of assessment"

51. Conducted by Professor Nigel DS Bax University of Sheffield

52. Workshop held by Faculty of Medicine - Alexandria University on 15 April

2008 under the title:"Principles of test construction and delivery "

53. Conducted by Professor Nigel DS Bax University of Sheffield

54. Workshop held by the Faculty of Medicine - Alexandria University from 13 to

14 April 2008 under the title: Developing curriculum plans.

55. Conducted by Professor Nigel DS Bax University of Sheffield

56. Workshop held at the Faculty of Medicine - Alexandria University on 16 May

2008 under the title: The future of Medical education Workshop

57. Workshop held at the Faculty of Medicine - Alexandria University on 10 and

13-14 June 2009 "Introduction and detection of nanoparticles in mammalian

cells

58. Workshop held at the Faculty of Medicine - University of Alexandria on 12

June 2009 "Frontiers of nanotechnology workshop"

59. A Workshop held by the Faculty of Medicine - Alexandria University on 10

June 2009 under the title: Overview of the Grants Arena finding Funding and

Writing Winning Proposals"

60. Workshop held under the International Conference of Nanotechnology in

Cancer at the Faculty of Medicine - Alexandria University on 28 December

2010 under the title: Gold nanoparticles: preparation and characterization

workshop

Resume last Update November 2018 11

61. Workshop held at the Faculty of Medicine - Alexandria University on 15

December 2010 under the title: Introduction to e-course

62. Workshop held at the Faculty of Pharmacy - Mansoura University on 8 - 7

February 2010 under the title: Computer Based Drug Design

63. Workshop held in Alexandria on April 1, 2010 under the title: "The third

annual healthcare quality and accreditation symposium, accreditation passing

over the challenges"

64. E- assessment in Pharmacology. IUPHAR satellite symposium –

Pharmacology Education for Clinical Students. – Copenhagen .

65. Workshop held at the Faculty of Pharmaceutical Sciences - University of

Copenhagen on 17 July 2010 "Empowering Effective Teaching in

Pharmacology for a safer tomorrow" –IUPHAR satellite symposium –

Pharmacology Education for Clinical Students. Copenhagen

66. Workshop held under the International Conference of Nanotechnology in

Cancer at the Faculty of Medicine - Alexandria University on 26 December

2010 under the title: Biological Micro Electro Mechanical Systems

(BioMEMS): Fundamentals and Applications Workshops

67. Workshop held at the Faculty of Medicine - Alexandria University on 8 - 7

May 2011 under the title: The use of "Interactive Computerized Simulation

Software Programs" in Pharmacology Practical Classes.

68. Workshop held on 16-18 March 2011 for the training of pharmacists under the

activities The 46th National Congress of Allergy & Immunology & the 3rd

NAIC meeting

69. Workshops of the development of the capacity of faculty members and leaders

at the University of Alexandria:

o Teaching evaluation (T5) July 24-26,2007

o Research Management (R5), January 26-28, 2008

o Teaching with technology (T3) February 2-4,2008

o Preparing Research Project (R3),February 19-21,2008

o University Administration(L2)February 2-4,2008

Financial & Legal Affairs (L3), February 23-25,2008

- Proposed project to STDF under title of : Bitter receptor modulation: insider to

management of neurodegenerative and inflammatory disorders.2017;

resubmitted 2018

- Award from :The Egyptian Association of advancement of Medical Basic

Sciences,

June 2013

- Award from :Pan Arab Society of Interventional Cardiology „Cardio Alex

2009” June 23-26 2009

Resume last Update November 2018 12

- Certificate of Appreciation and Excellence from Elsevier as a reviewer 2015

- Reviewing many research papers for Scientific international Journals as

ACTA Endocrinologica , Alexandria journal of Medicine, Arabian Journal of

medical sciences